Anti-aging composition containing fermented propolis

Abstract

The present invention relates to a composition containing fermented propolis extract as an active ingredient and a method for preparing the same. The composition containing fermented propolis extract according to the present invention as an active ingredient may be used for various purposes such as improving wrinkles or skin elasticity, whitening, moisturizing, antioxidation or anti-inflammatory properties, and the composition can show better effects by increasing the content of artepillin C through the method for preparing the composition according to the present invention.

Claims

1. The first step involves producing propolis extract by cold extraction of raw propolis wax at a temperature of 5°C to 40°C, The second stage involves ultrasonic extraction of the propolis extract obtained in the first stage, The third step involves fermenting the extract obtained in the second step with a fermentation strain, The process includes a fourth step of solvent extraction of 20-40% by weight of 1,3-butylene glycol based on the total weight of the extract fermented in the third step, The aforementioned propolis is green propolis. The aforementioned low-temperature extraction is performed using a solvent selected from the group consisting of ethanol, propyl alcohol, and butyl alcohol. A method for producing a fermented propolis extract in which the artepillin C content is increased compared to an extract obtained by heat extraction of raw green propolis by heating it in a water bath at 60 degrees Celsius with a solvent solution of 1,3-butylene glycol and distilled water in a 50:50 ratio, stirring for 1 hour.

2. The method for producing a fermented propolis extract with increased artepillin C content according to claim 1, wherein the second stage of ultrasonic extraction is performed at a wavelength of 10 kHz to 40 kHz and a temperature of 10°C to 40°C.

3. The third stage fermentation strains are Lactobacillus acidophilus, Lactobacillus casei, and Lactobacillus bulgaricus. Artepillin C according to claim 1, characterized by being one or more selected from the group consisting of Lactobacillus bulgaricus, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus confusus, Lactobacillus fermentum, Lactobacillus brevis, and Thermus thermophilus. A method for producing fermented propolis extract with increased content of C).

4. The method for producing a fermented propolis extract with increased artepillin C content according to claim 1, wherein the third stage of fermentation is cultured for 65 to 80 hours.

5. A fermented propolis extract produced by the manufacturing method described in claim 1.

6. A cosmetic composition for improving skin wrinkles or skin elasticity, comprising the fermented propolis extract described in claim 5 as an active ingredient, wherein the propolis is green propolis.

7. A cosmetic composition for skin whitening, comprising the fermented propolis extract described in claim 5 as an active ingredient, wherein the propolis is green propolis.

8. A cosmetic composition for antioxidant purposes for the skin, comprising the fermented propolis extract described in claim 5 as an active ingredient, wherein the propolis is green propolis.

9. An anti-inflammatory cosmetic composition comprising the fermented propolis extract described in claim 5 as an active ingredient, wherein the propolis is green propolis.

10. The cosmetic composition according to any one of claims 6 to 9, wherein the fermented propolis extract is contained in an amount of 0.01 to 15% by weight relative to the total weight of the cosmetic composition.

11. The aforementioned fermentation involves Lactobacillus acidophilus, Lactobacillus casei, and Lactobacillus bulgaricus. A cosmetic composition according to any one of claims 6 to 9, comprising one or more strains selected from the group consisting of Lactobacillus bulgaricus, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus confusus, Lactobacillus fermentum, Lactobacillus brevis, and Thermus thermophilus.

12. A method for improving skin wrinkles or skin elasticity, comprising the steps of administering or applying a composition containing the fermented propolis extract described in Claim 5 to a subject or the skin of a subject, and improving skin wrinkles or skin elasticity on the subject or the skin of a subject, wherein the propolis is green propolis.

13. The cosmetic composition according to claim 7, comprising the steps of administering or applying a composition containing fermented propolis extract to a subject or the skin of a subject, and improving the whitening of the skin on the subject or the skin of the subject.

14. A method for antioxidant treatment of skin, comprising the steps of administering or applying a composition containing the fermented propolis extract described in Claim 5 to a subject or the skin of a subject, and inhibiting or reducing the oxidation of the subject or the skin of a subject, wherein the propolis is green propolis.

15. The cosmetic composition according to claim 9, comprising the steps of administering or applying a composition containing fermented propolis extract to a subject or the skin of a subject, and suppressing or reducing the occurrence of inflammation in the subject or the skin of a subject.

Images