Microspheres containing antibodies having melanin production inhibitory effects and their uses

Abstract

The present invention relates to microspheres containing antibodies having melanin production inhibitory efficacy and the uses thereof. Specifically, the present invention relates to microspheres containing antibody peptides having melanin production inhibitory activity, a cosmetic composition for skin whitening containing said microspheres as an active ingredient, and a pharmaceutical composition for the prevention or treatment of skin pigmentation disorders. The microspheres according to the present invention are designed to stably contain antibody peptides having melanin production inhibitory efficacy within them and to effectively penetrate into the skin, thereby further enhancing skin whitening efficacy. Accordingly, the microspheres according to the present invention can be usefully used as materials for functional cosmetics for skin whitening and pharmaceuticals for pigmentation disorders.

Description

Technology Field

[0001] The present invention relates to microspheres containing antibody peptides having melanin production inhibitory efficacy, and to cosmetics for skin whitening and treatments for skin pigmentation utilizing the same. Background Technology

[0002] Skin pigmentation is caused by the overproduction of melanin and can be triggered by UV exposure, inflammatory responses, genetic factors, and the like. Existing melanin-inhibiting technologies have limited efficacy and suffer from the problem of insufficient delivery systems, making it difficult to penetrate sufficiently into the skin. Accordingly, there is a need for a technology capable of penetrating deep into the skin to provide a sustained whitening effect. The problem to be solved

[0003] The present invention aims to provide a technology capable of effectively delivering microspheres containing antibody peptides that inhibit melanin deep into the skin. Through this, the invention seeks to solve the problems of existing technologies and contribute to improving the effects of skin whitening and the treatment of pigmentation disorders. means of solving the problem

[0004] The present invention provides microspheres comprising antibody peptides having melanin production inhibitory activity, which can be utilized to develop functional cosmetic and pharmaceutical compositions. The microspheres are designed to stably deliver antibodies upon application to the skin, maintain efficacy, and effectively inhibit melanin production. Furthermore, the microspheres of the present invention may be composed of natural and synthetic polymers with excellent biocompatibility and possess the function of effectively penetrating the skin barrier to release active ingredients over a long period. This can improve upon the short-term effectiveness issues associated with existing cosmetics or pharmaceuticals.

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[0007] Effects of the invention

[0008] . Specific details for implementing the invention

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Claims

Claim 1 Microspheres containing an antibody peptide having melanin production inhibitory activity. Claim 2 A microsphere according to claim 1, characterized in that the antibody peptide is included in an amount of 1 to 10 weight percent based on the total weight of the microsphere. Claim 3 A cosmetic composition for skin whitening comprising the microspheres of claim 1 as an active ingredient. Claim 4 A cosmetic composition for skin whitening according to claim 1, wherein the microspheres have melanin production inhibitory activity and tyrosinase inhibitory activity. Claim 5 A cosmetic composition for skin whitening according to claim 4, characterized in that the composition comprises formulations such as skin lotion, toner, cream, essence, cleansing foam, shampoo, and body lotion. Claim 6 A pharmaceutical composition for the prevention or treatment of skin pigmentation disorders comprising the microspheres of claim 1 as an active ingredient. Claim 7 A pharmaceutical composition for the prevention or treatment of skin pigmentation disorders according to claim 6, characterized in that the skin pigmentation disorder is selected from the group consisting of melasma, freckles, black spots, nevi, drug-induced pigmentation, post-inflammatory pigmentation, and hyperpigmentation occurring in dermatitis. Claim 8 In claim 1, the microspheres are characterized by having hydrophilic or hydrophobic properties and having a surface modified to increase skin absorption rate. Claim 9 In claim 1, the microsphere is characterized by comprising nano-sized particles and being manufactured to maximize skin penetration efficiency. Claim 10 A cosmetic composition for skin whitening characterized in that a functional cosmetic containing the microspheres of claim 1 can be combined alone or with a vitamin C derivative, arbutin, kojic acid, or niacinamide to enhance the whitening function.

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