Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels
WO2024123815A8PCT designated stage expired Publication Date: 2025-07-03VERTEX PHARMACEUTICALS INC
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Patent Information
- Application Number
- PCT/US2023/082576
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2022-12-06
- Filing Date
- 2023-12-05
- Publication Date
- 2025-07-03
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Figure US2023082576_03072025_PF_FP_ABST
Abstract
Provided in this application is a process for making a compound of formula (I) and pharmaceutically acceptable salts thereof, which are useful as inhibitors of sodium channels. Also provided in this application is a process for making a compound of formula (II) and pharmaceutically acceptable salts thereof, which are useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.
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