Method for preparing tembotrione-containing weeding composition

Abstract

The present invention relates to the technical field of the preparation of weeding compositions. Disclosed in the present invention is a method for preparing a tembotrione-containing weeding composition. The method specifically comprises the following steps: charging tembotrione, oxaziclomefone and a modified coconut oil barrel-mixing auxiliary agent in a stirring kettle, fully stirring same, pumping the mixture into a high-speed shearing machine, shearing same, then pumping same into a sand mill, and fully sanding same. In the method for preparing a tembotrione-containing weeding composition, since coconut oil itself has anti-inflammatory, antioxidant, anticancer, skin moisturizing and other properties, in the present technical solution, the coconut oil is modified, i.e., the modified coconut oil barrel-mixing auxiliary agent is prepared and added into the composition, such that by reducing the contact angle between a medicine liquid and leaves and the surface tension of the medicine liquid, the drying time can be shortened, a synergistic effect is generated on the weeding composition, and the weeding effect of the weeding composition is improved. In addition, the dosage is reduced, while the weeding effect is ensured.

Description

Preparation method of herbicidal composition containing tembotrione Technical Field

[0001] The invention relates to the technical field of herbicide composition preparation, in particular to a method for preparing a herbicide composition containing tembotrione. Background Art

[0002] Referring to a Chinese patent application (Publication No. CN108077282A), a synergistic herbicide composition containing the active ingredients tembotrione and oxaziclomefone is described. The weight ratio of the active ingredients tembotrione to oxaziclomefone can range from 1:50 to 50:1. Efficacy tests have shown that the composition exhibits positive characteristics such as strong complementarity, significant synergistic effects, a broadened herbicidal spectrum, reduced application rates, extended application periods, high crop safety, reduced environmental pollution, and strong environmental compatibility. However, this composition relies solely on the interaction between tembotrione and oxaziclomefone to enhance herbicidal efficacy, which is relatively limited. Therefore, the present invention provides a method for preparing a herbicide composition containing tembotrione to address these issues. Summary of the Invention

[0003] (1) Technical problems solved

[0004] In view of the deficiencies in the prior art, the present invention provides a method for preparing a herbicidal composition containing tembotrione, which solves the problems mentioned in the above background technology.

[0005] (2) Technical solution

[0006] To achieve the above objectives, the present invention is implemented through the following technical scheme: a method for preparing a herbicide composition containing tembotrione, which specifically comprises the following steps: adding tembotrione, oxaziclomefone and modified coconut oil as a barrel mix adjuvant into a stirring kettle, stirring thoroughly, pumping into a high-speed shearing machine for shearing, and then pumping into a sand mill for thorough sand grinding.

[0007] Preferably, the weight ratio of tembotrione to oxaziclomefone is 1:50 to 50:1, and the mass content of tembotrione and oxaziclomefone in the composition is 80 to 95%.

[0008] Preferably, the specific modification method of the modified coconut oil barrel mix auxiliary agent is:

[0009] (1) Take 10 mL of coconut oil and place it in a 200 mL round-bottom flask. Add 40 mL of 2% NaOH-CH3OH solution and shake to mix the two thoroughly.

[0010] (2) Place the round-bottom flask in an oil bath and heat it;

[0011] (3) Add 80 mL of 3% H2SO4-CH3OH solution and continue heating in the oil bath. After the reaction, cool the sample to room temperature.

[0012] (4) Then transfer the sample to a 250 mL separatory funnel and add 10 mL of 20 g / L NaHCO3 solution. Let it stand for stratification, remove the water layer, and wash 2-3 times.

[0013] (5) Add 10 mL of distilled water, let it stand for stratification, remove the water layer, and wash 2-3 times;

[0014] (6) Finally, add 4.0 g of anhydrous Na2SO4 for drying and filter with filter paper. The collected filtrate is the modified coconut oil barrel mix additive.

[0015] Preferably, in step (2) and step (3), the oil bath temperature is both 75-85°C.

[0016] Preferably, the oil bath heating time in step (2) is 10-20 minutes, and the oil bath heating time in step (3) is 8-12 minutes.

[0017] Preferably, the composition can be formulated into any one of powder, granules, solution, emulsifiable concentrate, emulsion, concentrated suspension and aerosol.

[0018] (3) Beneficial effects

[0019] The present invention provides a method for preparing a herbicidal composition containing tembotrione. Compared with the prior art, the method has the following advantages: Since coconut oil itself has anti-inflammatory, antioxidant, anti-cancer, and skin-moisturizing properties, the present invention modifies it to prepare a modified coconut oil tank mix adjuvant, which is then added to the composition. This method can reduce the contact angle between the liquid and the leaves and the liquid surface tension, thereby shortening the drying time, thereby synergizing the herbicidal composition and improving its weed control effect. Furthermore, while maintaining the weed control effect, the dosage is reduced. DETAILED DESCRIPTION

[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Example 1

[0021] The herbicidal composition containing tembotrione is obtained by the following method:

[0022] 10 g of tembotrione, 80 g of oxazolidinone and 10 g of modified coconut oil barrel mix additive were put into a stirring tank, stirred thoroughly, pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

[0023] Among them, the specific modification method of the modified coconut oil barrel mix additive is:

[0024] (1) Take 10 mL of coconut oil and place it in a 200 mL round-bottom flask. Add 40 mL of 2% NaOH-CH3OH solution and shake to mix the two thoroughly.

[0025] (2) Place the round-bottom flask in an oil bath at 75°C and heat for 10 minutes;

[0026] (3) Add 80 mL of 3% H2SO4-CH3OH solution and continue heating in an oil bath at 75 °C for 8 minutes. After the reaction, cool the sample to room temperature.

[0027] (4) Then transfer the sample to a 250 mL separatory funnel and add 10 mL of 20 g / L NaHCO3 solution. Let it stand to separate the layers, remove the water layer, and wash twice.

[0028] (5) Add 10 mL of distilled water, let it stand to separate the layers, remove the water layer, and wash twice;

[0029] (6) Finally, add 4.0 g of anhydrous Na2SO4 for drying and filter with filter paper. The collected filtrate is the modified coconut oil barrel mix additive. Example 2

[0030] The herbicidal composition containing tembotrione is obtained by the following method:

[0031] 45 g of tembotrione, 50 g of oxaziclomefone and 5 g of modified coconut oil barrel mix additive were put into a stirring tank, stirred thoroughly, pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

[0032] Among them, the specific modification method of the modified coconut oil barrel mix additive is:

[0033] (1) Take 10 mL of coconut oil and place it in a 200 mL round-bottom flask. Add 40 mL of 2% NaOH-CH3OH solution and shake to mix the two thoroughly.

[0034] (2) Place the round-bottom flask in an oil bath at 80°C and heat for 15 minutes;

[0035] (3) Add 80 mL of 3% H2SO4-CH3OH solution and continue heating in an 80°C oil bath for 10 minutes. After the reaction, cool the sample to room temperature.

[0036] (4) Then transfer the sample to a 250 mL separatory funnel and add 10 mL of 20 g / L NaHCO3 solution. Let it stand to separate the layers, remove the water layer, and wash three times.

[0037] (5) Add 10 mL of distilled water, let it stand to separate the layers, remove the water layer, and wash twice;

[0038] (6) Finally, add 4.0 g of anhydrous Na2SO4 for drying and filter with filter paper. The collected filtrate is the modified coconut oil barrel mix additive. Example 3

[0039] The herbicidal composition containing tembotrione is obtained by the following method:

[0040] 40 g of tembotrione, 40 g of oxazithromycin and 20 g of modified coconut oil barrel mix additive were put into a stirring tank, stirred thoroughly, pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

[0041] Among them, the specific modification method of the modified coconut oil barrel mix additive is:

[0042] (1) Take 10 mL of coconut oil and place it in a 200 mL round-bottom flask. Add 40 mL of 2% NaOH-CH3OH solution and shake to mix the two thoroughly.

[0043] (2) Place the round-bottom flask in an oil bath at 85°C and heat for 20 minutes;

[0044] (3) Add 80 mL of 3% H2SO4-CH3OH solution and continue heating in an oil bath at 85 °C for 12 minutes. After the reaction, cool the sample to room temperature.

[0045] (4) Then transfer the sample to a 250 mL separatory funnel and add 10 mL of 20 g / L NaHCO3 solution. Let it stand to separate the layers, remove the water layer, and wash three times.

[0046] (5) Add 10 mL of distilled water, let it stand to separate the layers, remove the water layer, and wash three times;

[0047] (6) Finally, add 4.0 g of anhydrous Na2SO4 for drying and filter with filter paper. The collected filtrate is the modified coconut oil barrel mix additive.

[0048] Comparative Example 1

[0049] The herbicidal composition containing tembotrione is obtained by the following method:

[0050] 10 g of tembotrione, 80 g of oxazolidinone and 10 g of coconut oil barrel mix additive were put into a stirring tank, stirred thoroughly, pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

[0051] Comparative Example 2

[0052] The herbicidal composition containing tembotrione is obtained by the following method:

[0053] 20 g of tembotrione and 80 g of oxazithromycin were put into a stirring tank, stirred thoroughly, and then pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

[0054] Comparative Example 3

[0055] The herbicide is tembotrione.

[0056] Comparative Example 4

[0057] The herbicide is oxazithromycin.

[0058] Seed treatment:

[0059] Select seeds of crabgrass, grass, retroflexus, and ramie that are full and undamaged, wash them with a 0.3% sodium hypochlorite solution, and set aside;

[0060] Crabgrass: Soak in 300mg / L GA3 for 48 hours and set aside;

[0061] Barnyard grass: soak in 1000mg / L GA3 for 24 hours and set aside;

[0062] Amaranthus retroflexus: Soak the seeds in 200 mg / L GA3 for 24 hours under light conditions and set aside.

[0063] Crown chrysanthemum: Soak the hemp seeds in 60℃ warm water for 30 minutes, then take them out and soak them in 300mg / L GA3 for 24 hours. When the seeds turn white, set aside.

[0064] Pretreated, uniformly grown seeds of crabgrass, barnyard grass, Amaranthus retroflexus, and chrysanthemum were planted in pots of identical dimensions. The test soil consisted of a 2:2:1 mixture of nutrient soil, vermiculite, and wood ash. The soil was kept moist during the incubation process. A foliar spray method was used for the test. When the weeds reached the two-leaf, one-heart stage, they were sprayed with a 3WP-2000 mobile spray tower. The results are shown in Table 1.

[0065]

[0066]

[0067] Wherein, CK is the number or fresh weight of weeds in the control area (i.e., the area without treatment); PT is the number or fresh weight of weeds in the treated area.

[0068] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0069] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0070] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A method for preparing a herbicidal composition containing tembotrione, characterized in that: The specific steps include: Cyclosulfuron, oxazithromycin and modified coconut oil barrel mix additives were put into a stirring kettle, stirred thoroughly, pumped into a high-speed shearing machine for shearing, and then pumped into a sand mill for thorough sand grinding.

2. The method for preparing a herbicidal composition containing tembotrione according to claim 1, characterized in that: The weight ratio of tembotrione to oxazithromycin is 1:50 to 50:1, and the mass content of tembotrione and oxazithromycin in the composition is 80 to 95%.

3. The method for preparing a herbicidal composition containing tembotrione according to claim 1, characterized in that: The specific modification method of the modified coconut oil barrel mix auxiliary agent is: (1) Take 10 mL of coconut oil into a 200 mL round-bottom flask, add 40 mL of 2% NaOH-CH3OH solution, and shake to mix the two thoroughly; (2) Place the round-bottom flask in an oil bath and heat it; (3) Add 80 mL of 3% H2SO4-CH3OH solution and continue heating in the oil bath. After the reaction, cool the sample to room temperature. (4) Then transfer the sample to a 250 mL separatory funnel and add 10 mL of 20 g / L NaHCO3 solution. Allow to stand for stratification, remove the water layer, and wash 2-3 times. (5) Add 10 mL of distilled water, let stand to separate the layers, remove the water layer, and wash 2-3 times; (6) Finally, add 4.0 g of anhydrous Na2S04 for drying and filter using filter paper. The collected filtrate is the modified coconut oil barrel mix additive.

4. The method for preparing a herbicidal composition containing tembotrione according to claim 3, characterized in that: In step (2) and step (3), the oil bath temperature is 75-85°C.

5. The method for preparing a tembotrione-containing herbicidal composition according to claim 3, characterized in that: The oil bath heating time in step (2) is 10-20 minutes, and the oil bath heating time in step (3) is 8-12 minutes.

6. The method for preparing a tembotrione-containing herbicidal composition according to claim 3, characterized in that: The composition can be formulated into any one of powder, granule, solution, emulsifiable concentrate, emulsion, concentrated suspension and aerosol.

7. A herbicidal composition containing tembotrione, characterized in that: Specifically include: Tank mix adjuvant of tembotrione, oxazithromycin and modified coconut oil.

8. Use of the tembotrione-containing herbicidal composition according to any one of claims 1 to 6 for controlling annual and perennial grass weeds and broadleaf weeds in corn fields.

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