RAPD inspection system and method using HMD, and application using same

Abstract

Provided are a RAPD inspection system and method using an HMD, and an application using the same. The RAPD inspection system using an HMD according to an embodiment of the present invention includes: a pupil stimulation unit for performing pupil stimulation for independently applying light to the two pupils of a body and thereby changing the size of the pupils; a stimulation information acquisition unit for acquiring stimulation information including information about the size of the pupils which changes according to the amount of the light; an abnormality determination unit for determining the presence of an abnormality, that is, the presence of an RAPD in the pupils, using the stimulation information; a correction information generation unit for generating correction information for checking the degree of the RAPD and using the correction information to further obtain additional stimulation information when a RAPD is determined to be present as a result of the determination regarding the presence of an abnormality; and a test result output unit for combining the stimulation information and the additional stimulation information to output a test result for the two pupils.

Description

RAPD inspection system, method, and application using HMD

[0001] The present invention relates to a RAPD examination system and method using an HMD and to applications using the same, and more particularly, to a RAPD examination system and method using an HMD and applications using the same, which can more easily perform RAPD examination and output the results using an HMD device that can be worn by a user on the human body, such as a VR or MR device, and can emit light to the pupil.

[0002]

[0003] In general, when an abnormality in the afferent pathway is suspected but no abnormality was found in a previous light reflex test, an alternating light test is performed to examine for relative afferent pupillary movement disorder. When the light reflex is abnormal due to a lesion of the afferent nerves in the light reflex from the retina to the midbrain, it is called an afferent pupillary defect (APD), and a relative afferent pupillary defect (RAPD) refers to a case in which the light reflex is different in both eyes due to a unilateral or asymmetrical lesion in the afferent nerve pathway.

[0004] If a relative afferent pupillary defect can be consistently observed by alternately illuminating both pupils, this can be an important sign suggesting a lesion in one optic nerve, optic chiasm, or optic tract.

[0005] For this purpose, a conventional test was performed. The conventional test is configured to perform an alternating light test to measure the RAPD, which involves (1) having the subject look at a distant target in a dark place, (2) rapidly shining a penlight alternately on both eyes for 3 to 5 seconds and checking the pupillary response of the eyes, and performing an evaluation after repeating the test several times (here, checking the dilation and constriction of the pupils during the time of shining the light). (3) Perform the alternating light test in cycles of 2 to 3 times, and if the sizes of the two eyes are different, perform a dark-light joint test. (4) If one or both eyes do not respond or are weak to the direct or opposite eye, a pupillary accommodation response test is performed.

[0006] In the case of these conventional tests, there is a problem in that the results vary depending on the skill of the examiner because they are performed using a pen light.

[0007] As a prior art related to this, there is KR10-2355455.

[0008]

[0009] In order to solve the problems of the prior art as described above, one embodiment of the present invention provides a RAPD test system using an HMD capable of performing RAPD test using an HMD device, a method, and an application using the same.

[0010]

[0011] According to one aspect of the present invention for solving the above-mentioned problem, a RAPD inspection system using an HMD is provided.

[0012] The RAPD test system using the HMD includes a pupil stimulation unit that independently applies illumination to each of two pupils of the body to perform pupil stimulation to change the size of the pupils; a stimulus information acquisition unit that acquires stimulus information including information on the size of the pupil that changes according to the amount of illumination; an abnormality determination unit that determines whether or not the RAPD of the pupil is abnormal using the stimulus information; a correction information generation unit that generates correction information for confirming the degree of the RAPD when the abnormality determination result determines that it is the RAPD and further acquires additional stimulus information using the correction information; and a test result output unit that accumulates the stimulus information and the additional stimulus information and outputs a test result for the two pupils.

[0013] The pupil stimulation unit may include at least two lighting modules capable of applying the lighting to each of the two pupils; and a darkroom creation module formed to include at least one of the lighting modules and formed to create a darkroom in each of the two pupils to prevent the inflow of light from the outside.

[0014] The above stimulus information acquisition unit may include an initial pupil size information acquisition module that acquires the initial pupil size information, wherein the stimulus information includes at least one of initial pupil size information, first pupil size change information, and second pupil size change information; and a change pupil size information acquisition module that acquires the first pupil size change information, which is a change in the sizes of the two pupils, by emitting a maximum amount of light to one of the two pupils for a preset period of time, and acquires the second pupil size change information, which is a change in the sizes of the two pupils, by emitting a maximum amount of light to the remaining pupil for the preset period of time.

[0015] The above initial pupil size information may include information on the change in the size of the two pupils obtained by maintaining the light in the pupil stimulator for a preset period of time without turning it on.

[0016] The above abnormality determination unit may include a maximum average value acquisition module that obtains a maximum average value, which is an average value of the maximum size of the two pupils when the light does not exist, using the stimulus information; a pupil response value acquisition module that obtains a pupil response value when the light is emitted to one of the two pupils using the maximum average value; and an abnormality determination result acquisition module that determines the abnormality using the pupil response value and obtains the abnormality determination result.

[0017] The above pupil response value acquisition module can, when the light is emitted to either of the two pupils, distinguish between the main pupil, which is the pupil from which the light is emitted, and the auxiliary pupil, which is the pupil from which the light is not emitted, and acquire the size values ​​of the main pupil and the auxiliary pupil, respectively, derive the average size value of the two pupils, and then acquire the pupil response value using the maximum average value.

[0018] The above correction information generation unit may include an RAPD determination module that determines whether or not the RAPD is present using the result of the determination of whether or not the abnormality is present; an adjusted illumination intensity information generation module that generates adjusted illumination intensity information to match the RAPD pupil response value, which is the pupil response value of the pupil determined to be the RAPD among the two pupils, with the normal pupil response value, which is the pupil response value of the remaining pupils; and a measurement repetition module that obtains the additional stimulus information using the correction information including the adjusted illumination intensity information.

[0019] The above test result includes actual measurement values ​​for the two pupils and information on size change over time for the two pupils using accumulated stimulus information, which is information that accumulates the stimulus information and the additional stimulus information, and the actual measurement values ​​include the initial pupil size information, the first pupil size change information, the second pupil size change information, and the final pupil size change information, and the size change information over time is expressed as a graph and can be output by correcting measurement error values ​​by applying a filter as needed.

[0020] According to one aspect of the present invention, a RAPD test method using an HMD is provided. The RAPD test method using an HMD includes: a pupil stimulation step of performing pupil stimulation by independently applying illumination to two pupils of a body using a pupil stimulation unit to change the size of the pupils; a stimulus information acquisition step of acquiring stimulus information including information on the size of the pupil that changes according to the amount of illumination using a stimulus information acquisition unit; an abnormality determination step of determining whether the pupil is RAPD or not using the stimulus information through an abnormality determination unit; a correction information generation step of generating correction information for confirming the degree of the RAPD using a correction information generation unit when the abnormality determination result determines the RAPD and further acquiring additional stimulus information using the correction information; and a test result output step of accumulating the stimulus information and the additional stimulus information using a test result output unit and outputting a test result for the two pupils.

[0021] According to one aspect of the present invention, an application utilizing a RAPD test method using an HMD is provided. The application utilizing the RAPD test method using the HMD is stored in a storage medium of a digital terminal to perform a pupil stimulation step of independently applying illumination to two pupils of a body to change the size of the pupils; a stimulus information acquisition step of acquiring stimulus information including information on the size of the pupil that changes according to the amount of illumination using a stimulus information acquisition unit; an abnormality determination step of determining whether the pupil is RAPD or not using the stimulus information through an abnormality determination unit; a correction information generation step of generating correction information for confirming the degree of the RAPD using a correction information generation unit when the abnormality determination result determines the RAPD and further acquiring additional stimulus information using the correction information; and a test result output step of accumulating the stimulus information and the additional stimulus information using a test result output unit and outputting a test result for the two pupils.

[0022]

[0023] The RAPD inspection system, method and application using the same using an HMD according to one embodiment of the present invention have the effect of enabling RAPD inspection to be performed with high accuracy regardless of the skill level of the inspector by using an HMD device.

[0024]

[0025] Figure 1 is a block diagram of a RAPD inspection system using an HMD according to an embodiment of the present invention.

[0026] Figure 2 is a block diagram of the pupil stimulation unit of Figure 1.

[0027] Figure 3 is a block diagram of the stimulus information acquisition unit of Figure 1.

[0028] Fig. 4 is a block diagram of the abnormality judgment unit of Fig. 1.

[0029] Fig. 5 is a block diagram of the correction information generation unit of Fig. 1.

[0030] Figure 6 is a flowchart of a RAPD test method using an HMD according to one embodiment of the present invention.

[0031] Figure 7 is a flowchart of step S13 of Figure 6.

[0032] Figure 8 is a flowchart of step S15 of Figure 6.

[0033] Figure 9 is a flowchart of step S17 of Figure 6.

[0034] Fig. 10 is an example diagram of an inspection result output unit and an output of step S19 according to one embodiment of the present invention.

[0035]

[0036] Hereinafter, some embodiments of the present disclosure will be described in detail with reference to exemplary drawings. When adding reference numerals to components in each drawing, identical components may have the same numerals as much as possible even if they are shown in different drawings. In addition, when describing the present embodiments, if it is determined that a detailed description of a related known configuration or function may obscure the gist of the technical idea of ​​the present invention, the detailed description may be omitted. When "includes," "has," "consists of," etc. are used in this specification, other parts may be added unless "only" is used. When a component is expressed in the singular, it may include a case in which the plural is included unless there is a special explicit description.

[0037] Additionally, terms such as first, second, A, B, (a), (b), etc. may be used to describe components of the present disclosure. These terms are only intended to distinguish the components from other components, and the nature, order, sequence, or number of the components are not limited by the terms.

[0038] In a description of the positional relationship of components, when it is described that two or more components are "connected," "combined," or "connected," it should be understood that the two or more components may be directly "connected," "combined," or "connected," but that the two or more components may also be further "interposed" with another component to be "connected," "combined," or "connected." Here, the other component may be included in one or more of the two or more components that are "connected," "combined," or "connected" to each other.

[0039] In the description of the temporal flow relationship related to components, operation methods, or manufacturing methods, for example, when the temporal or flow relationship is described as “after”, “following”, “next to”, “before”, etc., it may also include cases where it is not continuous, unless “immediately” or “directly” is used.

[0040] Meanwhile, when numerical values ​​or corresponding information (e.g., levels, etc.) for components are mentioned, even without separate explicit description, the numerical values ​​or corresponding information may be interpreted as including an error range that may occur due to various factors (e.g., process factors, internal or external impact, noise, etc.).

[0041] FIG. 1 is a block diagram of a RAPD inspection system using an HMD according to an embodiment of the present invention, FIG. 2 is a block diagram of a pupil stimulation unit of FIG. 1, FIG. 3 is a block diagram of a stimulation information acquisition unit of FIG. 1, FIG. 4 is a block diagram of an abnormality determination unit of FIG. 1, and FIG. 5 is a block diagram of a correction information generation unit of FIG. 1.

[0042] Hereinafter, a RAPD inspection system (1, hereinafter referred to as inspection system for convenience) using an HMD according to one embodiment of the present invention will be described in detail using FIGS. 1 to 5.

[0043] An inspection system (1) according to one embodiment of the present invention is configured to emit light to two pupils of a human body according to conditions using an HMD, measure the size of the pupils that expand or contract in response to the light, process the size, and output an RAPD inspection result.

[0044] To this end, an inspection system (1) according to one embodiment of the present invention is formed to include a pupil stimulation unit (11), a stimulation information acquisition unit (13), an abnormality determination unit (15), a correction information generation unit (17), and an inspection result output unit (19), as illustrated in FIG. 1.

[0045] The pupil stimulation unit (11) is configured to perform pupil stimulation by independently applying light to each of the two pupils of the body to change the size of the pupils. In one embodiment of the present invention, the pupil stimulation unit (11) is configured using a VR device, but the present invention is not limited thereto, and various HMD devices capable of emitting light to each of the two pupils may be used as the pupil stimulation unit (11). The pupil stimulation unit (11) may include a lighting module (111) and a darkroom generation module (113), as illustrated in FIG. 2.

[0046] At least two lighting modules (111) may be provided to provide illumination to each of the two pupils, and the darkroom generation module (113) may be formed to include at least one lighting module and may be formed to create a darkroom in each of the two pupils to prevent the inflow of light from the outside. The darkroom generation module (113) does not necessarily have to be formed so that no light leaks in, and if it can create a space below a set illuminance, the space can be defined as a darkroom.

[0047] The stimulus information acquisition unit (13) is configured to acquire stimulus information including pupil size information that changes according to the amount of light. Here, the stimulus information may include at least one of initial pupil size information, first pupil size change information, and second pupil size change information. For this purpose, the stimulus information acquisition unit (13) may include an initial pupil size information acquisition module (131) and a change pupil size information acquisition module (133), as illustrated in FIG. 3.

[0048] The initial pupil size information acquisition module (131) is configured to acquire initial pupil size information. In the present invention, the initial pupil size information includes size change information of two pupils acquired when the pupil stimulator (11) is kept off-light for a preset period of time. In this case, when the sizes of the two pupils no longer change within the preset period of time, or the sizes of the two pupils at the preset period of time can be included in the size change information as maximum size information of the two pupils. In addition, maximum size information of the two pupils can be acquired for each pupil.

[0049] The change pupil size information acquisition module (133) is configured to acquire first pupil size change information, which is a change in the size of the two pupils, by emitting the maximum amount of light to one of the two pupils for a preset period of time, and to acquire second pupil size change information, which is a change in the size of the two pupils, by emitting the maximum amount of light to the other pupil for a preset period of time. Hereinafter, the pupil on the side from which light is emitted is defined as the main pupil, and the pupil on the side from which light is not emitted is defined as the auxiliary pupil. In addition, the first pupil size change information and the second pupil size change information may each include minimum size information, which is a reduced minimum size of the two pupils.

[0050] The abnormality determination unit (15) is configured to determine whether the RAPD of the pupil is abnormal or not using stimulus information. To this end, the abnormality determination unit (15) according to one embodiment of the present invention may be configured to include a maximum average value acquisition module (151), a pupil response value acquisition module (153), and an abnormality determination result acquisition module (155), as illustrated in FIG. 4.

[0051] The maximum average value acquisition module (151) is configured to acquire the maximum average value, which is the average of the maximum sizes of the two pupils when there is no illumination, using stimulus information.

[0052] The pupil response value acquisition module (153) is configured to acquire the pupil response value when light is emitted to either of the two pupils using the maximum average value. Here, the pupil response value acquisition module (153) distinguishes between the main pupil, which is the pupil from which light is emitted, and the auxiliary pupil, which is the pupil from which light is not emitted, when light is emitted to either of the two pupils, and acquires the size values ​​of the main pupil and the auxiliary pupil, respectively, derives the average size value of the two pupils, and then acquires the pupil response value using the maximum average value.

[0053] The abnormality determination result acquisition module (155) is configured to determine whether there is an abnormality using the pupil response value and obtain the abnormality determination result.

[0054] The abnormality determination result acquisition module (155) of the present invention performs a comparison between the pupil response value and the previously stored normal pupillary movement data, and if the pupil response value is outside the normal pupillary movement data range, it determines that there is an abnormality in the main pupil, and can obtain the abnormality determination result for the main pupil.

[0055] In addition, the abnormality determination result acquisition module (155) of the present invention performs a comparison between the pupil response value and the previously stored normal pupillary movement data, and if the pupil response value does not fall outside the normal pupillary movement data range, it determines that there is no abnormality in the primary pupil, and can acquire the abnormality determination result for the primary pupil.

[0056] The correction information generation unit (17) is configured to generate correction information for confirming the degree of RAPD when the result of the abnormality determination is determined to be RAPD, and to further acquire additional stimulus information using the correction information. To this end, the correction information generation unit (17) according to one embodiment of the present invention is configured to include an RAPD determination module (171), an adjusted illumination intensity information generation module (173), and a measurement repetition module (175), as illustrated in FIG. 5.

[0057] The RAPD judgment module (171) is configured to determine whether or not there is an RAPD using the result of the abnormality judgment. Here, the RAPD judgment module (171) can determine the main pupil as an RAPD if it obtains the result of the abnormality judgment that there is an abnormality in the main pupil.

[0058] When a specific pupil is determined to be RAPD in the RAPD determination module (171), the adjusted illumination intensity information generation module (173) can generate adjusted illumination intensity information to match the RAPD pupil response value, which is the pupil response value of the pupil determined to be RAPD among the two pupils, with the normal pupil response value, which is the pupil response value of the remaining pupils.

[0059] Here, the controlled illumination intensity information can be expressed by the following mathematical expression 1.

[0060] [Mathematical Formula 1]

[0061] L = Initial light intensity * (1-RAPD pupil response) / (1-normal pupil response)

[0062] (where L: controlled lighting intensity information)

[0063] When the adjusted illumination intensity information is obtained, the measurement repetition module (175) of the present invention can be configured to obtain additional stimulus information using correction information including the adjusted illumination intensity information. The measurement repetition module (175) of the present invention can be configured to re-obtain the response values ​​of the two pupils using the adjusted illumination intensity information, use the same to check whether the response values ​​of the two pupils are included in the normal pupil sway data range, and repeat the measurement a preset number of times to obtain additional stimulus information. The measurement repetition module (175) can repeat the measurement a preset number of times even if the response values ​​of the two pupils are included in the normal pupil sway data range, and if the response values ​​of the two pupils are still outside the normal pupil sway data range, it can repeatedly obtain the adjusted illumination intensity information using the mathematical expression 1 and then perform the measurement using the corresponding information. Even in this case, the measurement repetition module (175) of one embodiment of the present invention can be configured to repeat the measurement a preset number of times.

[0064] The test result output unit (19) of the present invention is configured to output the test result by accumulating stimulus information and additional stimulus information. The test result output from the test result output unit (19) of the present invention may include actual measured values ​​for two pupils and information on size changes over time for the two pupils using the accumulated stimulus information. For example, the test result may include the time at which the change in pupil size over time was recorded, the intensity of light entering the left pupil, the size of the left pupil, the intensity of light entering the right pupil, and the size of the right pupil.

[0065] To illustrate the test results of the present invention using a more detailed example, the test results may include the intensity of light entering the left pupil when no light is emitted, the maximum size of the left pupil, the intensity of light entering the right pupil, and the maximum size of the right pupil.

[0066] Additionally, the test results may include the intensity of light entering the left pupil when light is emitted into the left pupil, the minimum size of the left pupil, the intensity of light entering the right pupil, and the minimum size of the right pupil.

[0067] Additionally, the test results may include the intensity of light entering the left pupil when light is emitted into the right pupil, the minimum size of the left pupil, the intensity of light entering the right pupil, and the minimum size of the right pupil.

[0068] The actual measurement values ​​output as a test result may include initial pupil size information, first pupil size change information, second pupil size change information, and final pupil size change information, and the final pupil size change information may include the intensity of light entering the two pupils and the average size value of the two pupils at the corresponding time using the last measured stimulus information. An example of such actual measurement value output is illustrated in Fig. 10a.

[0069] The Value result screen illustrated in Fig. 10a is an actual measurement value output screen that shows the pupil size values ​​measured as maximum and minimum values ​​in each case. Here, Max Pupil refers to the maximum pupil size value in the initial dark environment.

[0070] OS Light refers to the minimum pupil size when light first enters the left pupil, and OD Light refers to the minimum pupil size when light first enters the right pupil (initial light intensity = 1). The reason why OS Light and OD Light use the initial examination data where light enters each pupil is to check the pupil response when the same light intensity is emitted to the pupil.

[0071] Last Pupil refers to the intensity of light entering each pupil during the last examination and the average pupil size value when the last light entered each pupil.

[0072] In the screen of Fig. 10a, the light intensity was adjusted to 0.89 to make the size of the OD the same as the OS during the last inspection, and at that time, it can be confirmed that the average size of the pupil is 3.31 when light of intensity 1 enters the left, and the average size of the pupil is 3.23 when light of intensity 0.89 enters the right.

[0073] Information on size changes over time is expressed as a graph, and a filter can be applied as needed to output a graph that compensates for measurement errors. Here, the filter is applied using a filtering level value input from an external administrator or user, and can be expressed as the following mathematical equation (2).

[0074] [Equation 2]

[0075] N(n)=N(n-1)*(1-F)+N(n)*F

[0076] (Here, N(n): nth frame value, F: filtering degree value)

[0077] Figure 10b shows an example of outputting size change information over time.

[0078] The Graph result screen shown in Fig. 10b is a screen showing the change in pupil size over time. In the graph, none Light refers to the part where the pupil is dilated in a dark state, and in one embodiment of the present invention, it may refer to initial pupil size information. OS Light indicates the reaction of the left pupil to light when light enters only the left eye, and OD Light indicates the reaction of the right pupil to light when light enters only the right eye. In addition, the line indicates the size of the left pupil, and the red line indicates the size of the right pupil. The graph in the background area indicates the range (area) of the Hippus Normal Data. In Fig. 10b, each box is represented by 3 boxes, which means that the preset measurement time is 3 seconds. However, in the present invention, the preset measurement time is not limited to 3 seconds, and a preset measurement time greater or less than that may be applied. In a specific embodiment of the present invention, the preset measurement time is defined as 5 seconds.

[0079] Smooth Option is an option that applies a Low Pass Filter to smooth out changes in the size and bounce of the pupil. It corresponds to the filter in the description above, and the number below Smooth Option corresponds to the filtering degree value in the description above. If you do not want to apply Smooth Option, you can set the filtering degree value to 1 and output the original data through the calculation of the above-described mathematical formula 2.

[0080] Meanwhile, FIGS. 6 to 9 illustrate a RAPD test method using an HMD according to an embodiment of the present invention. FIG. 6 is a flowchart of a RAPD test method using an HMD according to an embodiment of the present invention, FIG. 7 is a flowchart of step S13 of FIG. 6, FIG. 8 is a flowchart of step S15 of FIG. 6, and FIG. 9 is a flowchart of step S17 of FIG. 6.

[0081] For convenience of explanation, the following description uses the system of FIG. 1, but the present invention is not limited thereto and various devices, apparatuses or systems capable of performing similar operations may be used.

[0082] An inspection method (10) according to one embodiment of the present invention is configured to emit light to two pupils of a human body according to conditions using an HMD, measure the size of the pupils that expand or contract in response to the light, process the size, and output an RAPD inspection result.

[0083] To this end, an inspection method (10) according to one embodiment of the present invention is formed to include a pupil stimulation step (S11), a stimulation information acquisition step (S13), an abnormality determination step (S15), a correction information generation step (S17), and an inspection result output step (S19), as illustrated in FIG. 6.

[0084] The pupil stimulation step (S11) is configured to perform pupil stimulation by independently applying light to each of the two pupils of the body using a pupil stimulation unit to change the size of the pupils. In one embodiment of the present invention, the pupil stimulation step (S11) is performed using a VR device, but the present invention is not limited thereto, and the pupil stimulation step (S11) can be performed using various HMD devices capable of emitting light to each of the two pupils.

[0085] The stimulus information acquisition step (S13) is configured to acquire stimulus information including pupil size information that changes according to the amount of light using a stimulus information acquisition unit. Here, the stimulus information may include at least one of initial pupil size information, first pupil size change information, and second pupil size change information. For this purpose, the stimulus information acquisition step (S13) may include an initial pupil size information acquisition step (S131) ​​and a changed pupil size information acquisition step (S133), as illustrated in FIG. 7.

[0086] The initial pupil size information acquisition step (S131) ​​is configured to acquire initial pupil size information. In the present invention, the initial pupil size information includes size change information of two pupils acquired when the light is not turned on and maintained for a preset period of time in the pupil stimulation step (S11). At this time, when the sizes of the two pupils no longer change within the preset period of time, or the sizes of the two pupils at the preset period of time can be included in the size change information as maximum size information of the two pupils. In addition, maximum size information of the two pupils can be acquired for each pupil.

[0087] The step of obtaining change pupil size information (S133) is configured to obtain first pupil size change information, which is a change in the sizes of the two pupils, by emitting the maximum amount of light to one of the two pupils for a preset period of time, and to obtain second pupil size change information, which is a change in the sizes of the two pupils, by emitting the maximum amount of light to the other pupil for a preset period of time. Hereinafter, the pupil on the side from which light is emitted is defined as the main pupil, and the pupil on the side from which light is not emitted is defined as the auxiliary pupil. In addition, the first pupil size change information and the second pupil size change information may each include minimum size information, which is a reduced minimum size of the two pupils.

[0088] The abnormality determination step (S15) is configured to determine whether the RAPD of the pupil is abnormal using stimulus information in the abnormality determination unit. To this end, the abnormality determination step (S15) according to one embodiment of the present invention may be configured to include a maximum average value acquisition step (S151), a pupil response value acquisition step (S153), and an abnormality determination result acquisition step (S155), as illustrated in FIG. 8.

[0089] The maximum average value acquisition step (S151) is configured to acquire the maximum average value, which is the average of the maximum sizes of the two pupils when there is no light, using stimulus information.

[0090] The pupil response value acquisition step (S153) is configured to acquire the pupil response value when light is emitted to either of the two pupils using the maximum average value. Here, the pupil response value acquisition step (S153) distinguishes between the main pupil, which is the pupil from which light is emitted, and the auxiliary pupil, which is the pupil from which light is not emitted, when light is emitted to either of the two pupils, and acquires the size values ​​of the main pupil and the auxiliary pupil, respectively, and derives the average size value of the two pupils, and then acquires the pupil response value using the maximum average value.

[0091] The step of obtaining the result of determining whether there is an abnormality (S155) is configured to obtain the result of determining whether there is an abnormality by using the pupil response value to determine whether there is an abnormality.

[0092] The step (S155) of obtaining the result of determining whether there is an abnormality of the present invention performs a comparison between the pupil response value and the previously stored normal pupil movement data, and if the pupil response value is outside the range of normal pupil movement data, it is determined that there is an abnormality in the main pupil, and the result of determining whether there is an abnormality in the main pupil can be obtained.

[0093] In addition, the step (S155) of obtaining the result of determining whether there is an abnormality of the present invention compares the pupil response value with the previously stored normal pupil movement data, and if the pupil response value does not fall outside the range of normal pupil movement data, it is determined that there is no abnormality in the main pupil, and the result of determining whether there is an abnormality in the main pupil can be obtained.

[0094] The correction information generation step (S17) is configured to generate correction information to confirm the degree of RAPD in the correction information generation unit when the result of the abnormality determination is determined to be RAPD, thereby obtaining additional stimulus information using the correction information. To this end, the correction information generation step (S17) according to one embodiment of the present invention is configured to include an RAPD determination step (S171), an adjusted illumination intensity information generation step (S173), and a measurement repetition step (S175), as illustrated in FIG. 9.

[0095] The RAPD determination step (S171) is configured to determine whether or not RAPD exists using the abnormality determination result. Here, the RAPD determination step (S171) can determine the primary pupil as RAPD if the abnormality determination result determines that there is an abnormality in the primary pupil.

[0096] In the RAPD determination step (S171), if a specific pupil is determined to be RAPD, the adjusted illumination intensity information generation step (S173) can generate adjusted illumination intensity information to match the RAPD pupil response value, which is the pupil response value of the pupil determined to be RAPD among the two pupils, with the normal pupil response value, which is the pupil response value of the remaining pupils.

[0097] Here, the adjusted illumination intensity information can be expressed by the above mathematical expression 1.

[0098] When the adjusted illumination intensity information is obtained, the measurement repetition step (S175) of the present invention can be configured to obtain additional stimulus information using correction information including the adjusted illumination intensity information. The measurement repetition step (S175) of the present invention can be configured to re-obtain the response values ​​of the two pupils using the adjusted illumination intensity information, use this to check whether the response values ​​of the two pupils are included in the normal pupil sway data range, and repeat the measurement a preset number of times to obtain additional stimulus information. The measurement repetition step (S175) can repeat the measurement a preset number of times even if the response values ​​of the two pupils are included in the normal pupil sway data range, and when the response values ​​of the two pupils are still outside the normal pupil sway data range, the adjusted illumination intensity information can be obtained repeatedly using the mathematical expression 1, and then the measurement can be performed using the information. Even in this case, the measurement repetition step (S175) of one embodiment of the present invention can be configured to repeat the measurement a preset number of times.

[0099] The test result output step (S19) of the present invention is configured to output the test result by accumulating stimulus information and additional stimulus information using the test result output unit. The test result output in the test result output step (S19) of the present invention may include actual measured values ​​for two pupils and information on size changes over time for the two pupils using the accumulated stimulus information. For example, the test result may include the time at which the change in pupil size over time was recorded, the intensity of light entering the left pupil, the size of the left pupil, the intensity of light entering the right pupil, and the size of the right pupil.

[0100] To illustrate the test results of the present invention using a more detailed example, the test results may include the intensity of light entering the left pupil when no light is emitted, the maximum size of the left pupil, the intensity of light entering the right pupil, and the maximum size of the right pupil.

[0101] Additionally, the test results may include the intensity of light entering the left pupil when light is emitted into the left pupil, the minimum size of the left pupil, the intensity of light entering the right pupil, and the minimum size of the right pupil.

[0102] Additionally, the test results may include the intensity of light entering the left pupil when light is emitted into the right pupil, the minimum size of the left pupil, the intensity of light entering the right pupil, and the minimum size of the right pupil.

[0103] The actual measurement values ​​output as a test result may include initial pupil size information, first pupil size change information, second pupil size change information, and final pupil size change information, and the final pupil size change information may include the intensity of light entering the two pupils and the average size value of the two pupils at the corresponding time using the last measured stimulus information. An example of such actual measurement value output is illustrated in Fig. 10a.

[0104] The Value result screen illustrated in Fig. 10a is an actual measurement value output screen that shows the pupil size values ​​measured as maximum and minimum values ​​in each case. Here, Max Pupil refers to the maximum pupil size value in the initial dark environment.

[0105] OS Light refers to the minimum pupil size when light first enters the left pupil, and OD Light refers to the minimum pupil size when light first enters the right pupil (initial light intensity = 1). The reason why OS Light and OD Light use the initial examination data where light enters each pupil is to check the pupil response when the same light intensity is emitted to the pupil.

[0106] Last Pupil refers to the intensity of light entering each pupil during the last examination and the average pupil size value when the last light entered each pupil.

[0107] In the screen of Fig. 10a, the light intensity was adjusted to 0.89 to make the size of the OD the same as the OS during the last inspection, and at that time, it can be confirmed that the average pupil size is 3.31 when light of intensity 1 enters the left, and the average pupil size is 3.23 when light of intensity 0.89 enters the right.

[0108] Information on size changes over time is expressed as a graph, and a filter can be applied as needed to output a graph that compensates for measurement errors. Here, the filter is applied using a filtering degree value input from an external administrator or user, and can be expressed as the mathematical expression 2 above.

[0109] Figure 10b shows an example of outputting size change information over time.

[0110] The Graph result screen shown in Fig. 10b is a screen showing the change in pupil size over time. In the graph, none Light refers to the part where the pupil is dilated in a dark state, and in one embodiment of the present invention, it may refer to initial pupil size information. OS Light refers to the reaction of the left pupil to light when light enters only the left eye, and OD Light refers to the reaction of the right pupil to light when light enters only the right eye. In addition, the green line indicates the size of the left pupil, and the red line indicates the size of the right pupil. The graph in the background area indicates the range (area) of the Hippus Normal Data. In Fig. 10b, each cell is represented by three cells, which means that the preset measurement time is three seconds. However, in the present invention, the preset measurement time is not limited to three seconds, and a preset measurement time greater or less than that may be applied. In a specific embodiment of the present invention, the preset measurement time is defined as five seconds.

[0111] The Smooth Option applies a Low Pass Filter to smooth out pupil size changes and bounce values. It corresponds to the filter described above, and the numbers below the Smooth Option correspond to the filtering degree described above. If you do not wish to apply the Smooth Option, setting the filtering degree to 1 will allow the original data to be output through the calculation of Equation 2 described above.

[0112] The RAPD test method using an HMD according to the embodiments of the present invention described above can be implemented as an application (computer program) stored in a storage medium of a computer.

[0113] Here, the computer may include a RAPD inspection system using an HMD.

[0114] The computer's operating system may be an operating system such as Windows or Macintosh, which is installed on general PCs such as desktops and laptops, or a mobile-only operating system such as iOS or Android, which is installed on mobile devices such as smartphones and tablet PCs.

[0115] The RAPD examination method using the HMD according to the embodiments of the present invention described above may be implemented as an application (i.e., a computer program) installed by default on a computer or installed by a user, and may be stored (recorded) on a computer-readable storage medium.

[0116] According to embodiments of the present invention, an RAPD test method using an HMD is implemented and an application (computer program) stored and executed in a storage medium of a computer may perform a pupil stimulation step of independently applying illumination to two pupils of a body to change the size of the pupils; a stimulus information acquisition step of acquiring stimulus information including information on the size of the pupil that changes according to the amount of illumination using a stimulus information acquisition unit; an abnormality determination step of determining whether the pupil is RAPD or not using the stimulus information using an abnormality determination unit; a correction information generation step of generating correction information for confirming the degree of the RAPD using a correction information generation unit when the abnormality determination result determines the RAPD and further acquiring additional stimulus information using the correction information; and a test result output step of accumulating the stimulus information and the additional stimulus information using a test result output unit and outputting a test result for the two pupils.

[0117] In this way, in order for a computer to read a program recorded on a storage medium and execute the RAPD inspection method using an HMD according to the embodiments implemented as a program, the application (application program) described above may include code (Code) coded in a computer language such as C, C++, JAVA, or machine language that can be read by a computer processor (CPU).

[0118] Such code may include functional code related to functions defining the aforementioned functions, and may also include control code related to execution procedures required for the computer's processor to execute the aforementioned functions according to a predetermined procedure.

[0119] Additionally, such code may further include memory reference related code regarding where in the internal or external memory of the computer the additional information or media required for the computer's processor to execute the aforementioned functions should be referenced.

[0120] Additionally, if the computer's processor needs to communicate with any other computer or server, etc., located remotely in order to execute the functions described above, the code may further include communication-related code regarding how the computer's processor should communicate with any other computer or server, etc. located remotely, using the computer's communication module (e.g., wired and / or wireless communication module), and what information or media should be sent and received during the communication.

[0121] In addition, the functional program for implementing the present embodiments and the code and code segments related thereto may be easily inferred or changed by programmers in the technical field to which the present invention pertains, taking into consideration the system environment of the computer that reads the storage medium and executes the program.

[0122] Additionally, a computer-readable storage medium recording the aforementioned program can be distributed across network-connected computer systems, allowing the computer-readable code to be stored and executed in a distributed manner. In this case, one or more of the multiple distributed computers can execute some of the functions described above and transmit the results to one or more of the other distributed computers. The computer receiving the results can also execute some of the functions described above and provide the results to the other distributed computers.

[0123] As described above, a computer-readable storage medium that records an application for executing a RAPD inspection method using an HMD according to embodiments of the present invention may include, for example, a ROM, a RAM, a CD-ROM, a magnetic tape, a floppy disk, an optical media storage device, etc.

[0124] In addition, a computer-readable storage medium recording an application, which is a program for executing a RAPD inspection method using an HMD according to embodiments of the present invention, may be a storage medium (e.g., a hard disk, etc.) included in an application provider server including an application store server, a web server related to an application or a corresponding service, or the application provider server itself, or another computer recording the program or its storage medium.

[0125] A computer capable of reading a storage medium recording an application program for executing a RAPD test method using an HMD according to embodiments of the present invention may include not only general PCs such as general desktops or laptops, but also mobile terminals such as smart phones, tablet PCs, PDAs (Personal Digital Assistants), and mobile communication terminals, and should be interpreted as all computing-capable devices.

[0126] The above description is merely an illustrative illustration of the technical idea of ​​the present invention, and those skilled in the art will appreciate that various modifications and variations can be made without departing from the essential characteristics of the present invention. Therefore, the embodiments disclosed in the present invention are intended to illustrate, rather than limit, the technical idea of ​​the present invention, and the scope of the technical idea of ​​the present invention is not limited by these embodiments. The scope of protection of the present invention should be interpreted by the following claims, and all technical ideas within a scope equivalent thereto should be interpreted as being included in the scope of the rights of the present invention.

Claims

1. A pupil stimulation unit that performs pupil stimulation by independently applying light to each of the two pupils of the body to change the size of the pupils; A stimulus information acquisition unit that acquires stimulus information including information on the size of the pupil that changes according to the amount of light of the above lighting; An abnormality judgment unit that determines whether the RAPD of the pupil is abnormal or not using the above stimulus information; As a result of the above abnormality determination, if it is determined to be the RAPD, a correction information generation unit that generates correction information to confirm the degree of the RAPD and obtains additional stimulus information using the correction information; and A RAPD test system using an HMD, comprising: a test result output unit that accumulates the above stimulus information and the above additional stimulus information and outputs the test results for the two pupils.

2. In paragraph 1, The above pupil stimulation part is, At least two lighting modules are provided so as to apply said lighting to each of said two pupils; and A RAPD examination system using an HMD, comprising: a darkroom generating module formed to include at least one of the above lighting modules and formed to create a darkroom in each of the two pupils to prevent the inflow of light from the outside; 3. In paragraph 2, The above stimulus information acquisition unit is, The above stimulus information includes at least one of initial pupil size information, first pupil size change information, and second pupil size change information, An initial pupil size information acquisition module for acquiring the above initial pupil size information; and A RAPD examination system using an HMD, comprising: a change pupil size information acquisition module that acquires first pupil size change information, which is a change in the size of the two pupils, by emitting a maximum amount of light to one of the two pupils for a preset period of time, and acquires second pupil size change information, which is a change in the size of the two pupils, by emitting a maximum amount of light to the other pupil for the preset period of time.

4. In paragraph 3, A RAPD examination system using an HMD, wherein the above initial pupil size information includes information on changes in the size of the two pupils obtained by maintaining the light in the pupil stimulator for a preset period of time without turning on the light.

5. In paragraph 4, The above abnormality judgment department is, A maximum average value acquisition module that acquires a maximum average value, which is an average value of the maximum size of the two pupils when the light does not exist, by using the above stimulus information; A pupil response value acquisition module that acquires a pupil response value when the light is emitted to one of the two pupils using the maximum average value; and A RAPD inspection system using an HMD, comprising an abnormality determination result acquisition module that determines whether there is an abnormality using the pupil response value and obtains the abnormality determination result.

6. In paragraph 5, The above pupil response value acquisition module is, A RAPD examination system using an HMD, which, when the light is emitted to either of the two pupils, distinguishes between the main pupil, which is the pupil from which the light is emitted, and the auxiliary pupil, which is the pupil from which the light is not emitted, obtains the size values ​​of the main pupil and the auxiliary pupil, respectively, derives the average size value of the two pupils, and then obtains the pupil response value using the maximum average value.

7. In paragraph 6, The above correction information generation unit, A RAPD judgment module that uses the above abnormality judgment result to confirm whether the above RAPD exists or not; When the above RAPD is confirmed, an adjusted illumination intensity information generation module that generates adjusted illumination intensity information to match the RAPD pupil response value, which is the pupil response value of the pupil determined to be the RAPD among the two pupils, with the normal pupil response value, which is the pupil response value of the remaining pupil; and A RAPD examination system using an HMD, comprising: a measurement repetition module for obtaining the additional stimulus information using the correction information including the adjusted illumination intensity information; 8. In paragraph 7, The above test results include actual measurement values ​​for the two pupils and information on size changes over time for the two pupils using accumulated stimulus information, which is information that accumulates the stimulus information and the additional stimulus information. The above actual measurement value includes the initial pupil size information, the first pupil size change information, the second pupil size change information and the final pupil size change information, A RAPD inspection system using an HMD in which the above time-dependent size change information is expressed as a graph and the measurement error value is corrected by applying a filter as necessary.

9. A pupil stimulation step in which pupil stimulation is performed by independently applying light to each of the two pupils of the body using a pupil stimulation unit to change the size of the pupils; A stimulus information acquisition step for acquiring stimulus information including information on the size of the pupil that changes according to the amount of light of the lighting using a stimulus information acquisition unit; An abnormality judgment step for judging whether the RAPD of the pupil is abnormal or not by using the above stimulus information through an abnormality judgment unit; In the case where the result of the above abnormality determination is determined to be the RAPD, a correction information generation step for generating correction information to confirm the degree of the RAPD using a correction information generation unit and obtaining additional stimulus information using the correction information; and A RAPD test method using an HMD, comprising: a test result output step for accumulating the stimulus information and the additional stimulus information using a test result output unit and outputting the test results for the two pupils; 10. A pupil stimulation step in which pupil stimulation is performed by independently applying light to each of the two pupils of the body to change the size of the pupils; A stimulus information acquisition step for acquiring stimulus information including information on the size of the pupil that changes according to the amount of light of the above lighting; An abnormality determination step for determining whether the RAPD of the pupil is abnormal or not using the above stimulus information; In the case where the result of the above abnormality determination is determined to be the RAPD, a correction information generation step for generating correction information to confirm the degree of the RAPD and obtaining additional stimulus information using the correction information; and An application stored in a storage medium of a digital terminal to perform a test result output step of accumulating the above stimulus information and the above additional stimulus information and outputting the test results for the two pupils;

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