A subsassembly of a medicament delivery device for preventing a rigid needle shield from coming loose

Abstract

The present disclosure generally relates to medicament delivery devices, and particularly concerns a subassembly (35, 70, 82, 90, 112, 170) for preventing a rigid needle shield (43) from coming loose.

Description

[0001] A SUBSASSEMBLY OF A MEDICAMENT DELIVERY DEVICE FOR PREVENTING A RIGID NEEDLE SHIELD FROM COMING LOOSE

[0002] TECHNICAL FIELD

[0003] The present disclosure generally relates to medicament delivery devices, and particularly concerns a subassembly for preventing a rigid needle shield from coming loose.

[0004] BACKGROUND

[0005] A number of medical conditions require injections. These days, a number of different injection devices exist, including various types of pen injectors, autoinjectors and infusion devices for large volume injections. Although many of these devices have enabled major improvements in the management of a number of medical conditions, various limitations do still exist in the current technology. In considering these problems, the applicant has appreciated that various developments could be made to help improve the medicament delivery devices on the market today, for example concerning removal and handling of rigid needle shields that cover a needle of a syringe prior to use.

[0006] SUMMARY

[0007] An object of the present disclosure is to provide a subassembly for a medicament delivery device, which solves, or at least mitigates problems of the prior art.

[0008] According to a first aspect of the present disclosure, there is provided a subassembly of a medicament delivery device, which medicament delivery device extends from a proximal end adapted to face an injection site, to a distal end, along a longitudinal axis, the subassembly comprising: a cap arrangeable at a proximal end of the medicament delivery device to cover a needle shield, a cap cover arranged coaxial with and inside the cap, the cap cover comprising a cover structure arranged in a proximal opening of the cap, a distally facing surface configured to engage with a proximally facing surface of the cap when the cap is moved proximally with respect to the cap cover for removal of the cap from the medicament delivery device, a compartment for accommodating a removable needle shield, and radially inwards extending protrusions that engage with the distal end of the removable needle shield when the cap cover moves proximally, wherein the cap comprises at least one radially inwards extending structure that at least partly blocks a path for the removable needle shield out from the compartment of the cap cover such that the removable needle shield remains at least partly in the compartment after removal of the cap from the medicament delivery device.

[0009] Embodiments of the present disclosure advantageously provides for maintaining the removable needle shield, preferably a so-called rigid needle shield, RNS, inside the cap cover after removal from a syringe in a medicament delivery device. In other words, embodiments of the present invention advantageously prevent the removable needle shield from falling out from the cap cover and be lost and possible cause littering.

[0010] In the present disclosure, when the term “distal direction” is used, this refers to the direction pointing away from the dose delivery site during use of the medicament delivery device. When the term “distal part / end” is used, this refers to the part / end of the delivery device, or the parts / ends of the components thereof, which under use of the medicament delivery device is / are located furthest away from the dose delivery site. Correspondingly, when the term “proximal direction” is used, this refers to the direction pointing towards the dose delivery site during use of the medicament delivery device. When the term “proximal part / end” is used, this refers to the part / end of the delivery device, or the parts / ends of the members thereof, which under use of the medicament delivery device is / are located closest to the dose delivery site.

[0011] Further, the term “longitudinal”, “longitudinally”, “axially” or “axial” refer to a direction extending from the proximal end to the distal end, typically along the device or components thereof in the direction of the longest extension of the device and / or component. Similarly, the terms “transverse”, “transversal” and “transversally” refer to a direction generally perpendicular to the longitudinal direction.

[0012] Further, the terms “circumference”, “circumferential”, “circumferentially” refer to a circumference or a circumferential direction 301 relative to an axis 102, typically a central axis extending in the direction of the longest extension of the device and / or component. Similarly, “radial” or “radially” refer to a direction 302 extending radially relative to the axis, and “rotation”, “rotational” and “rotationally” refer to rotation relative to the axis.

[0013] According to one embodiment, the at least one radially inwards extending structure of the cap maybe at least one snap arm arranged in a slot of the cap cover. A snap arm provides for engaging the cap with the cap cover in a simple yet robust way.

[0014] According to one embodiment, the snap-arm may comprise a radially inwards extending protrusion that engages with the slot of the cap cover. The protrusion strengthens the engagement between the cap and cap cover since it can reach further into the slot.

[0015] According to one embodiment, the at least one snap arm maybe configured to pinch on the removable needle shield to prevent it from falling out from the compartment. A snap-arm is flexible, e.g., or springy or resiliently deformable such that it can snap into an original position when released from a deformed state. That is, if the removable needle shield push on the snaparm it will counter-act with a force which pinches the removable needle shield against an opposite surface. Hereby, an efficient mechanism for maintaining the removable needle shield in the cap cover is provided.

[0016] According to one embodiment, the subassembly may comprise two snap arms arranged on opposite sides of the compartment. Hereby, an even more efficient mechanism for maintaining the removable needle shield in the cap cover is provided. According to one embodiment, a distance between the snap-arms maybe less than a diameter of the removable needle shield.

[0017] According to one embodiment, the protrusions of the snap-arms maybe configured to pinch on the removable needle shield. Thus, the protrusions is the part of the snap-arms that reach the furthest radially inwards, thereby efficiently pinching on the removable needle shield.

[0018] According to one embodiment, the distally facing surface that may be configured to engage with the proximally facing surface of the cap is part of the cover structure.

[0019] According to another embodiment, the at least one radially inwards extending structure of the cap may be arranged proximally with respect to the cover structure of the cap cover. In other words, instead of being an internal structure, the radially inwards extending structure maybe arranged as an external structure that advantageously blocks part of the opening in the cover structure out from the compartment where the removable needle shield is located.

[0020] According to one embodiment, the at least one radially inwards extending structure of the cap maybe the proximal-most part of the subassembly.

[0021] According to one embodiment, the cap cover may comprise a distally extending hook having a proximally facing surface that engages with a distally facing surface of the cap so that a longitudinal gap between the at least one radially inwards extending structure and the cover structure of the cap cover is maintained larger than a minimum play. In other words, there is always ensured that the cover structure does not reach as far proximally as the at least one radially inwards extending structure, not even as far as the distal part of the at least one radially inwards extending structure.

[0022] According to one embodiment, the at least one radially inwards extending structure of the cap may extend to a position directly proximal of an opening of the cover structure of the cap cover into the compartment. Hereby, a reliable blocking of the removable needle shield is provided.

[0023] According to one embodiment, the radially inwards extending structure may at least partly block an opening in the cap cover into the compartment where the removable needle shield is located.

[0024] According to one embodiment, the radially inwards extending structure may reduce an available escape diameter of an opening in the cap cover to a diameter less than a diameter of the removable needle shield. The escape diameter is the maximum diameter an object can have and still escape fully from the compartment of the cap cover through the proximal opening. If the diameter of the removable needle shield is larger than the available escape diameter it cannot exit through the opening in the cap cover.

[0025] According to one embodiment, the at least one radially inwards extending structure of the cap may be arranged distally with respect to the cover structure of the cap cover. Moving the at least one radially inwards extending structure of the cap inside the cap body advantageously provides for avoiding any slots or other interruptions in the cap structure that the at least one radially inwards extending structure must slide through.

[0026] According to one embodiment, the radially inwards extending structure arranged distally with respect to the cover structure of the cap cover may be arranged to reduce an available escape diameter of an opening in the cap cover to a diameter less than a diameter of the removable needle shield. As above, the escape diameter is the maximum diameter an object can have and still escape fully from the compartment of the cap cover through the proximal opening. If the diameter of the removable needle shield is larger than the available escape diameter it cannot exit through the opening in the cap cover. In this case, with the radially inwards extending structure arranged distally with respect to the cover structure of the cap cover the removable needle shield maybe prevented to even reach the opening in the cap cover. According to one embodiment, the radially inwards extending structure may be arranged to engage with a proximal surface of the removable needle shield to prevent it from escaping through a proximal opening in the cap cover.

[0027] In embodiments, the proximal surface of the removable needle shield may be the proximal-most surface of the removable needle shield. In other words, the radially inwards extending structure is in front of the removable needle shield and inside a main body of the cap cover.

[0028] According to a second aspect of the present disclosure, there is provided a subassembly of a medicament delivery device, which medicament delivery device extends from a proximal end adapted to face an injection site, to a distal end, along a longitudinal axis, comprising: a cap arrangeable at a proximal end of the medicament delivery device to cover a needle shield, a cap cover arranged coaxial with and inside the cap, the cap cover comprising a cover structure arranged in a proximal opening of the cap, a distally facing surface configured to engage with a proximally facing surface of the cap when the cap is moved proximally with respect to the cap cover for removal of the cap from the medicament delivery device, a compartment for accommodating a removable needle shield, and radially inwards extending protrusions that engages with the distal end of the removable needle shield when the cap cover moves proximally, wherein the cap cover comprises a tubular body forming the compartment, the tubular body comprising a flexible arm fixed at both ends, the flexible arm is bent radially inwards to hold the removable needle shield in place in the compartment.

[0029] It was thus realized that an alternative way to prevent the removable needle shield from escaping from the cap cover is to provide the tubular body of the cap cover with at least one flexible arm that hold the removable needle shield in place. Stated in another way, the at least one flexible arm are configured to maintain the removable needle shield, preferably a so-called rigid needle shield, RNS, inside the cap cover after removal from a syringe in a medicament delivery device. According to one embodiment, where a centre portion of the flexible arm may pinch the removable needle shield against the opposite side of the compartment. Thus, the flexible arm is bent such that a centre portion of the flexible arm is the part of the flexible arm that reaches furthest radially inwards towards the removable needle shield. From a manufacturing point of view, this is likely the easiest to achieve.

[0030] According to one embodiment, one end of the flexible arm may be proximally arranged with respect to the other end of the flexible arm. That is the flexible arm may lay at least partly in a proximal-distal alignment which may facilitate manufacturing and provides an efficient mechanism for holding the removable needle shield in place.

[0031] According to one embodiment, the ends of the flexible arm may be aligned along an axis parallel with the longitudinal axis. The flexible arm may be a straight element or ribbon structure that reaches in parallel with the longitudinal axis.

[0032] According to one embodiment, the subassembly may comprise two flexible arms. This improves the ability of the subassembly to hold the removable needle shield in place.

[0033] According to one embodiment, the two flexible arms maybe arranged on opposite sides of the tubular body. This further improves the ability of the subassembly to hold the removable needle shield in place.

[0034] According to a third aspect of the present disclosure, there is provided a subassembly of a medicament delivery device, which medicament delivery device extends from a proximal end adapted to face an injection site, to a distal end, along a longitudinal axis, comprising: a cap arrangeable at a proximal end of the medicament delivery device to cover a needle shield, a cap cover arranged coaxial with and inside the cap, the cap cover comprising a cover structure arranged in a proximal opening of the cap, a distally facing surface configured to engage with a proximally facing surface of the cap when the cap is moved proximally with respect to the cap cover for removal of the cap from the medicament delivery device, a compartment for accommodating a removable needle shield, and radially inwards extending protrusions that engages with the distal end of the removable needle shield when the cap cover moves proximally, and a clip comprising at least one leg that is arranged between the removable needle shield and an inner surface of a wall of the compartment, the clip being arranged to squeeze the removable needle shield in a radial inwards direction to hold the removable needle shield in place in the compartment.

[0035] It was thus realized that an alternative way to prevent the removable needle shield from escaping from the cap cover is to arrange a clip in the cap cover that squeeze on the removable needle shield to hold it in place. Stated in another way, the clip is configured to maintain the removable needle shield, preferably a so-called rigid needle shield, RNS, inside the cap cover after removal from a syringe in a medicament delivery device.

[0036] According to one embodiment, the clip may be attached to the removable needle shield. Thus, to reduce the number of parts, the clip maybe part of the removable needle shield.

[0037] According to one embodiment, the clip may be squeezed by a radially inwards facing wall of the cap cover. Thus, the clip is tightly fitted between the wall and the removable needle shield to provide a strong force on the removable needle shield to maintain it in the cap cover.

[0038] According to one embodiment, a diameter of the volume inside the cap cover maybe tapered such that when the cap cover moves proximally with respect to the clip, the clip squeezes harder on the removable needle shield. The tapered shape of the cap cover provides an efficient way to increase the force on the removable needle shield as the cap cover moves proximally.

[0039] According to one embodiment, the clip may be a C-clip.

[0040] According to a fourth aspect of the present disclosure, there is provided a subassembly of a medicament delivery device, which medicament delivery device extends from a proximal end adapted to face an injection site, to a distal end, along a longitudinal axis, comprising: a cap arrangeable at a proximal end of the medicament delivery device to cover a needle shield, a cap cover arranged coaxial with and inside the cap, the cap cover comprising a cover structure arranged in a proximal opening of the cap, a distally facing surface configured to engage with a proximally facing surface of the cap when the cap is moved proximally with respect to the cap cover for removal of the cap from the medicament delivery device, a compartment for accommodating a removable needle shield, and radially inwards extending protrusions that engages with the distal end of the removable needle shield when the cap cover moves proximally, wherein the cap cover comprises a transversal arm on a proximal end that blocks a pathway of the removable needle shield out from the compartment through an opening on the cover structure, the transversal arm being arranged proximal to the opening.

[0041] It was thus realized that an alternative way to prevent the removable needle shield from escaping from the cap cover is to equip the cap cover with a transversal arm that blocks the pathway. Stated in another way, the transversal arm is configured to maintain the removable needle shield, preferably a so-called rigid needle shield, RNS, inside the cap cover after removal from a syringe in a medicament delivery device.

[0042] According to one embodiment, the transversal arm may be attached to the cap cover by a hinge on one end of the transversal arm and comprises a hook on the opposite end of the transversal arm that locks under a flange of the cap cover. In other words, the transversal arm maybe rotated about the hinged connected between an open position and a closed position. In the closed position the removable needle shield cannot escape from the cap cover through the proximal opening. To be able to move the transversal arm, as provide by the hinged connection, provides advantages during assembly of the medicament delivery device.

[0043] According to one embodiment, the cap may comprise a proximally extending flange that at least partly covers the hook of the transversal arm when locked to the flange of the cap cover. In this way, the flange of the cap blocks the hook of the transversal arm to disengage from the flange of the cap cover.

[0044] According to one embodiment, the transversal arm may be arranged to intercept the longitudinal axis.

[0045] There is further provided a medicament delivery device comprising the subassembly according to any one of the herein disclosed aspects or embodiments.

[0046] Generally, all terms used in the claims are to be interpreted according to their ordinary meaning in the technical field, unless explicitly defined otherwise herein. All references to "a / an / the member, apparatus, component, means, etc.” are to be interpreted openly as referring to at least one instance of the member, apparatus, component, means, etc., unless explicitly stated otherwise.

[0047] BRIEF DESCRIPTION OF THE DRAWINGS

[0048] The specific embodiments of the inventive concept will now be described, by way of example, with reference to the accompanying drawings, in which:

[0049] Fig. 1 is a perspective view of a medicament delivery device according to embodiments of the present disclosure;

[0050] Figs. 2A-B are perspective views of a cap according to embodiments of the present disclosure;

[0051] Figs. 3A-B are perspective views of a cap cover according to embodiments of the present disclosure;

[0052] Fig. 4A is a cross-section of a subassembly according to embodiments of the present disclosure;

[0053] Fig. 4B is a cross-section of a subassembly according to embodiments of the present disclosure; Fig. 4C is a cross-section of a subassembly according to embodiments of the present disclosure;

[0054] Figs. 5A-B are perspective views of a cap according to embodiments of the present disclosure;

[0055] Figs. 6A-B are perspective views of a cap cover according to embodiments of the present disclosure;

[0056] Fig. 7A is a cross-section of a subassembly according to embodiments of the present disclosure;

[0057] Fig. 7B is a cross-section of a subassembly according to embodiments of the present disclosure;

[0058] Fig. 7C is a cross-section of a subassembly according to embodiments of the present disclosure;

[0059] Fig. 7D is a cross-section of a subassembly according to embodiments of the present disclosure;

[0060] Figs. 8 is a perspective view of a cap cover according to embodiments of the present disclosure;

[0061] Fig. 9 is a cross-section of a subassembly according to embodiments of the present disclosure;

[0062] Fig. 10 is a cross-section of a subassembly according to embodiments of the present disclosure;

[0063] Fig. 11 is a perspective views of a cap according to embodiments of the present disclosure;

[0064] Figs. 12 is a perspective view of a cap cover according to embodiments of the present disclosure;

[0065] Fig. 13 is a cross-section of a subassembly according to embodiments of the present disclosure; Fig. 14 is a perspective views of a cap according to embodiments of the present disclosure;

[0066] Fig. 15 is a cross-section of the cap in fig. 14;

[0067] Figs. 16-17 are perspective views of a cap cover according to embodiments of the present disclosure;

[0068] Fig. 18 is a cross-section of the cap over in figs. 16-17;

[0069] Fig. 19 is a cross-section of a subassembly according to embodiments of the present disclosure;

[0070] DETAILED DESCRIPTION

[0071] The inventive concept will now be described more fully hereinafter with reference to the accompanying drawings, in which exemplifying embodiments are shown. The inventive concept may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided by way of example so that this disclosure will be thorough and complete, and will fully convey the scope of the inventive concept to those skilled in the art. Like numbers refer to like members throughout the description.

[0072] Fig. 1 shows an example of a medicament delivery device 1 such as an autoinjector according to embodiments of the present disclosure. The medicament delivery device 1 is configured to expel medicament from a medicament container via a medicament delivery member such as a needle, to a user at a dose delivery site. The medicament delivery device 1 extends from a proximal end la to a distal end ib relative to the axis 102.

[0073] The medicament delivery device 1 comprises a housing 3 with a window 4. The housing 3 has a proximal end 3a and a distal end 3b. A cap 5 is configured to cover a retractable needle shield that extends out from the proximal end 3 a of the housing 3. The cap 5 maybe removed from the housing by a linear motion along the longitudinal axis 102 in the proximal direction. In some embodiments, the device 1 comprises a curved interface 7 between the distal end 5b of the cap 5 and the proximal end 3a of housing 3 of the medicament delivery device 1. When the cap 5 is rotated about the longitudinal axis 102 with respect to the housing 3 the curved interface causes a proximal motion of the cap 5 while being rotated.

[0074] The cap 5 covers a needle shield that is typically spring -loaded and is retractable to expose a needle when pushed against an injection site for an injection action.

[0075] A medicament container is placed inside the housing 3 from which medicament is expelled under the action of a spring -loaded plunger.

[0076] Figs. 2A and 2B are perspective views of a cap 5 according to an embodiment of the present disclosure.

[0077] The cap 5 comprises a curved distally facing surface 9 that is part of the curved interface 7. The curved distally facing surface 9 interacts with a proximally facing surface of the housing 3 to cause the proximal motion of the cap 5 while being rotated.

[0078] The cap 5 comprises a proximally facing surface 11 in proximity to its proximal end 5a. The proximally facing surface 11 assists in moving a cap cover by engaging with a distally facing surface of the cap cover.

[0079] The proximally facing surface 11 generally forms a flange 12 with an opening 13. That is, the proximally facing surface 11 circumvents a central opening 13 in the cap 5. The opening maybe centred about the longitudinal axis 102. The flange 12 may comprise at least one distally extending grooves 15 to accommodate for a guiding pin 33 of the cap cover.

[0080] The cap 5 comprises at least one radially inwards extending structure 17 that reaches at least partly radially into the opening 13 such as to block a path through the opening 13. In this embodiment the at least one radially inwards extending structure 17 of the cap is at least one snap arm 17. The snap arm 17 comprises a fixed end 17a and a free end 17b where the free end 17b can flex or move with respect to the fixed end 17a. The fixed end 17a is the proximal end of the snap arm 17 and the free end 17b is the distal end of the snap arm 17.

[0081] The snap-arm 17 comprises a radially inwards extending protrusion 19 reaching radially into the opening 13. The cap 5 comprises two snap arms 17 arranged on opposite sides longitudinal axis 102.

[0082] The cap 5 comprises a main proximal opening 20 circumvented by a proximally extending flange 22.

[0083] Figs. 3A and 3B are perspective views of a cap cover 21 according to an embodiment of the present disclosure. The cap cover 21 comprises a cover structure 23 shaped as a flange on a proximal end 25a of the tubular main 25 body of the cap cover 23. The cover structure 23 comprises a distally facing surface 27.

[0084] The cap cover 21 has an inner compartment 29 for accommodating a removable needle shield. Furthermore, the cap cover 21 comprises radially inwards extending protrusions 31 on its distal end 25b that engage with a distal end of the removable needle shield when the cap cover 21 moves proximally.

[0085] The cap cover 21 here comprises a guiding pin 33 that reaches radially outwards from the main tubular body 25 of the cap cover. The guiding pin 33 is arranged to slide in the groove 15 of the cap 5.

[0086] The cap cover 21 comprises a slot 34, in this embodiment there are two opposing slots 34.

[0087] Fig. 4A is a cross-section of a subassembly 35 comprising the abovedescribed cap 5 arranged to cover the retractable needle shield 37. The cap cover 21 is arranged coaxial with and inside the cap 5. The cover structure 23 of the cap cover 21 is arranged in the proximal opening 20 of the cap 5. The distally facing surface 27 of the cover structure 21 faces the proximally facing surface 11 of the cap 5. Is this initial state of the subassembly 35, the cap 5 is releasably locked to the housing 3 by a rounded protrusion 39 fitted in an opening 41 in the cap 5.

[0088] A removable needle shield 43 is accommodated in the compartment 29 of the cap cover 21. The removable needle shield 43 is preferably a so-called rigid needle shield, RNS, that protects the needle 45 of the syringe 47.

[0089] The radially inwards extending protrusions 31 of the cap cover 21 comprises a proximally facing surface 49 that engages with the distal end 43b of the removable needle shield 43 when the cap cover 21 is moved distally.

[0090] The protrusions 19 of the snap-arms 17 of the cap 5 reach through the slots 34 in the cap cover 21 and towards the removable needle shield 43.

[0091] Fig 4B is a cross-section of the subassembly 35 when the cap 5 has moved proximally indicated by arrow 304 so that the proximally facing surface 11 of the cap 5 has engaged with the distally facing surface 27 of the cap cover 21 so that the cover 21 is pushed in the proximal direction 304. The locking between the protrusion 39 of the housing 3 and the opening 41 of the cap 5 is disengaged. The engagement between the protrusions 31 of the cap cover 31 and the distal end 43b of the removable needle shield 43 causes a proximal motion of the removable needle shield 43 with respect to the needle 45 when the cap cover 21 moves proximally.

[0092] The protrusions 19 of the snap-arms 17 of the cap 5 that reach through the slots 34 in the cap cover 21 are now proximally located with respect to the removable needle shield 43.

[0093] Fig 4C is a cross-section of the subassembly 35 when the subassembly has been removed from the housing 3. The protrusions 19 of the snap-arms 17 at least partly blocks a path for the removable needle shield 43 out from the compartment 29 of the cap cover 21 through its proximal opening 36. In this way, the removable needle shield 43 remains at least partly in the compartment 29 after removal of the cap 5 from the medicament delivery device 1 housing 3. The at least one snap arm 17 is configured to pinch on the removable needle shield 43 to prevent it from falling out from the compartment 29. In this case, the two oppositely located snap-arms 17 pinch on the removable needle 43 as it moves proximally. The removable needle shield 43 is somewhat tapered so that at least one diameter of the removable needle 43 is larger than the distance between the protrusion 19. In other words, the protrusions can capture the removable needle 43 between them.

[0094] Figs. 5A and 5B are perspective views of a cap 50 according to an embodiment of the present disclosure.

[0095] The cap 50 comprises the curved distally facing surface 9 at the distal end 5b, the flange 12, the openings 13, 20 and 41, and the flange 22 as discussed above with reference to cap 5 in figs 2A-B.

[0096] The cap 50 comprises a radially inwards extending structure 52, in this embodiment a single radially inwards extending structure 52 in the form of a pin or arm that reaches to a position proximal of the flange 22 and the opening 20 of the cap 50. There is thus a longitudinal gap 54 between the flange 22 and the radially inwards extending structure 52. Furthermore, the radially inwards extending structure 52 reaches to a position proximal of the opening 13 in the cap 50 such that the opening 13 is partly blocked.

[0097] The flange 12 of the cap comprises a through-hole 55.

[0098] Figs. 6A and 6B are perspective views of a cap cover 56 according to an embodiment of the present disclosure.

[0099] The cap cover 56 comprises the main tubular body 25, the compartment 29, the protrusions 31, the distally facing surface 27, and the cover structure 23 discussed above with reference to the cap cover 21 in figs 3A-B. The cap cover 56 comprises a longitudinal guide slot 58 in the cover structure 23 and the main body 25 in which a guide plate 59 of the cap 50 is fitted to guide the proximal motion between the cap 50 and the cap cover 56.

[0100] The cap cover 56 comprises distally extending arms 61 with a hook 63 having a proximally facing surface 65. The arms 61 can be fitted in a respective one of the through-holes 55 of the cap 50.

[0101] The cap cover 56 further comprises the proximal opening 36 which is partly blocked by the radially inwards extending structure 52 of the cap 50.

[0102] Fig. 7A is a cross-section of a subassembly 70 comprising the above-described cap 50 arranged to cover the retractable needle shield 37.

[0103] The cap cover 56 is arranged coaxial with and inside the cap 50. The cover structure 23 of the cap cover 56 is arranged in the proximal opening 20 of the cap 5. The distally facing surface 27 of the cover structure 56 faces the proximally facing surface 11 of the cap 50. Is this initial state of the subassembly 70, the cap 50 is releasably locked to the housing 3 by a rounded protrusion 39 fitted in an opening 41 in the cap 50.

[0104] A removable needle shield 43 is accommodated in the compartment 29 of the cap cover 21. The removable needle shield 43 is preferably a so-called rigid needle shield, RNS, that protects the needle 45 of the syringe 47.

[0105] The radially inwards extending protrusions 31 of the cap cover 21 comprises a proximally facing surface 49 that engages with the distal end 43b of the removable needle shield 43 when the cap cover 56 is moved distally.

[0106] The radially inwards extending structure 52 of the cap 50 is arranged proximally with respect to the cover structure 23 of the cap cover 23. More specifically, in this embodiment, the at least one radially inwards extending structure 52 of the cap 50 is the proximal-most part of the subassembly 70. This further advantageously provides a feature that prevents that the medicament delivery device 1 can be placed vertically and upright on a flat surface. The radially inwards extending structure 52 preferably extends to a position directly proximal of the opening 36 of the cover structure 23 of the cap cover 56 into the compartment 29.

[0107] The distally extending hooks 63 each having a proximally facing surface 65 can engages with a distally facing surface 67 of the cap 50 so that a longitudinal gap 54 between the at least one radially inwards extending structure 52 and the cover structure 23 of the cap cover 56 is maintained larger than a minimum play. The distally facing surface 67 is on the flange 12 of the cap 50.

[0108] Fig 7B is a cross-section of the subassembly 70 when the cap 50 has moved proximally indicated by arrow 304 so that the proximally facing surface 11 of the cap 50 has engaged with the distally facing surface 27 of the cap cover 21 so that the cap cover 56 is pushed in the proximal direction 304. The locking between the protrusion 39 of the housing 3 and the opening 41 of the cap 50 is disengaged. The engagement between the protrusions 31 of the cap cover 31 and the distal end 43b of the removable needle shield 43 causes a proximal motion of the removable needle shield 43 with respect to the needle 45 when the cap cover 56 moves proximally.

[0109] Figs 7C and 7D cross-sections of the subassembly 70 when the subassembly 70 has been removed from the housing 3.

[0110] The radially inwards extending structure 52 blocks a path for the removable needle shield 43 out from the compartment 29 of the cap cover 56. In other words, the removable needle shield 43 remains in the compartment 29 after removal of the cap 50 from the medicament delivery device 1.

[0111] The radially inwards extending structure 52 at least partly blocks the opening 36 in the cap cover 56 into the compartment where the removable needle shield 43 is located. Since the radially inwards extending structure 52 extends to an overlapping position of the opening 36 it reduces an available escape diameter of the opening 36 in the cap cover 56 to a diameter less than a diameter of the removable needle shield 43. Fig. 8 is a perspective view of a cap cover 8o of a subassembly 82. The cap cover comprises the protrusions 31 with distally facing surface 49, the cover structure 23, the distally extending hooks 63, and tubular main body 25 forming the compartment 29, discussed above.

[0112] Furthermore, the cap cover 80 comprises a flexible arm 84 fixed at both ends 84a and 84b.

[0113] In some embodiments, the cap cover may comprise two flexible arms 80. The two flexible arms may be arranged on opposite sides of the tubular body 25.

[0114] Fig. 9 is a cross-section of the subassembly 82 comprising the cap cover 80 in fig. 8. The flexible arm 84 is bent radially inwards to hold the removable needle shield 43 in place in the compartment 29.

[0115] The centre portion 86 of the flexible arm pinches the removable needle shield 43 against the opposite side 88 of the compartment 29. The opposite side 88 maybe an inner wall 88 of the cap cover 80 delimiting the compartment 29 of the cap cover 80.

[0116] The flexible arm 84 comprises a proximal end 84a and a distal end 84b. In this embodiment, the ends 84a-b of the flexible arm 84 are aligned with the longitudinal axis 102. The flexible arm 84 maybe shaped as a ribbon.

[0117] Fig. 10 is a cross-section of a subassembly 90 according to a further aspect. The subassembly 90 comprises a cap 50 and a cap cover 56 such as the once described with reference to figs 7A-C.

[0118] As above a removable needle shield 43 is accommodated in the compartment 29 of the cap cover 21. The removable needle shield 43 is preferably a so- called rigid needle shield, RNS, that protects the needle 45 of the syringe 47.

[0119] The radially inwards extending protrusions 31 of the cap cover 56 comprises a proximally facing surface 49 that engages with the distal end 43b of the removable needle shield 43 when the cap cover 56 is moved distally. In addition, the subassembly 90 comprises a clip 92 comprising at least one leg 94 that is arranged between the removable needle shield 43 and an inner surface 96 of a wall of the compartment 29. The clip 92 is arranged to squeeze the removable needle shield 43 in a radial inwards direction to hold the removable needle shield 43 in place in the compartment 29. In other words, the clip holds the removable needle shield 43 such that it maintains in the compartment 29 when the subassembly is removed from the housing 3 of the medicament delivery device 1.

[0120] The clip 92 is squeezed by a radially inwards facing wall 96 of the cap cover 56. For example, the inner wall 96 maybe tapered such that the clip, or the legs 94 thereof, is radially squeezed when the cap cover 56 moves proximally with respect to the clip 90. The clip 92 maybe a so-called C-clip.

[0121] In some embodiments, the clip 92 is attached to the removable needle shield 43. Alternatively, the clip 92 is part of the removable needle shield 43.

[0122] Fig. 11 is perspective view a cap no of a subassembly 112 according to the present disclosure. The cap 110 comprises the curved distally facing surface 9 at the distal end 5b, the flange 12, the openings 13, 20, and the flange 22 as discussed above with reference to cap 5, 50 in figs 2A-B, and figs 5A-B. The cap 110 comprises the through-hole 55 in the flange 12 as discussed with reference to cap 50.

[0123] Fig. 12 is a cap cover 114 of subassembly 112 according to the present disclosure. The cap cover 114 comprises the tubular body 25 that forms a compartment for the removable needle shield. The cap cover 114 comprises a transversal arm 116 on a proximal end 114a that at least partly blocks the opening 36 of the cover structure 23 through which a removable needle shield may otherwise escape the compartment in the cap cover 114.

[0124] The transversal arm 116 is arranged to intercept the longitudinal axis (102).

[0125] The transversal arm 166 is attached to the cap cover structure 23 by a hinge

[0126] 118 on one end of the transversal arm 116. The transversal arm 116 comprises a hook 120 on its opposite end. The hook that locks under a flange 122 of the cap cover. The flange 122 maybe part of the cap cover structure 23.

[0127] The cap cover 114 comprises the hooks 63 that are arranged through eh through-holes 55 of the cap no, like the embodiment of figs 7A-C.

[0128] Fig. 13 is a cross-section of the subassembly 112 comprising the cap 110 and the cap cover 114. The cap cover 114 is arranged coaxial with and inside the cap 110. The cap cover comprises the cover structure 23 arranged in a proximal opening 20 of the cap no. The proximally facing surface 11 of the cap 110 can engage with the distally facing surface 27 of the cap cover 114 when the cap 110 is moved proximally with respect to the cap cover 114 for removal of the cap 110 from the medicament delivery device.

[0129] The compartment 29 is adapted to for accommodating a removable needle shield. The radially inwards extending protrusions 31 of the cap cover 114 engages with a distal end of the removable needle shield when the cap cover 114 moves proximally, like the above discussed embodiment.

[0130] The cap cover 114 comprises the transversal arm 116 on a proximal end 114a that blocks a pathway of the removable needle shield out from the compartment 29 through the opening 36 of the cover structure 23. The transversal arm 116 is arranged proximal to the opening 36.

[0131] The flange 20 the cap no that extends proximally at least partly covers the hook 120 of the transversal arm 116 to prevent accidental release of the transversal arm.

[0132] Fig. 14 is perspective view of a cap 150 according to an embodiment of the present disclosure. Fig. 15 is a cross-section of the cap 150.

[0133] The cap 150 comprises the curved distally facing surface 9 at the distal end 5b, the flange 12, the openings 13, 20 and 41, and the flange 22 as discussed above with reference to cap 5 in figs 2A-B. The cap 150 further comprises a radially inwards extending structure 152, in this embodiment a single radially inwards extending structure 152 in the form of a pin or arm that is arranged inside the cap 150. The inwards extending structure 152 is distally arranged with respect to the flange 22 and the proximally facing surface 11, and therefore also the opening 20 of the cap 150. Furthermore, the radially inwards extending structure 152 reaches to a position in the opening 13 in the cap 150 such that the opening 13 is partly blocked.

[0134] The flange 12 of the cap 150 comprises through-holes 55.

[0135] The cap 150 further comprises a pocket 153 in the flange 12 with a proximally facing surface 154 that is distally located with respect to the surface 11.

[0136] Figs. 16 and 17 are perspective views of a cap cover 156 according to an embodiment of the present disclosure.

[0137] The cap cover 156 comprises the main tubular body 25, the compartment 29, the protrusions 31, the distally facing surface 27, and the cover structure 23 discussed above with reference to the cap cover 21 in figs 3A-B.

[0138] The cap cover 56 comprises a longitudinal guide slot 58 in the main body 25 in which the radially extending structure 152 of the cap 150 is fitted to guide the proximal motion between the cap 150 and the cap cover 156. The longitudinal slot 58 does not reach through the cover structure 23.

[0139] The cap cover 156 comprises distally extending arms 61 with a hook 63 having a proximally facing surface 65. The arms 61 can be fitted in a respective one of the through-holes 55 of the cap 150.

[0140] The cap cover 156 further comprises the proximal opening 36 which is partly blocked, form inside the cap cover 156 by the radially inwards extending structure 152 of the cap 150 such that the removable needle shield 43 cannot escape out from the cap cover 156. The cap cover 156 comprises a guide protrusion 159 that is arranged opposite the slot 58 and that extends distally from the surface 27 and radially from the body 25 of the cap cover 156. The guide protrusion 156 is configured to be fitted in the pocket 153 of the cap 150 to prevent rotational motion between the cap 150 and the cap cover 156.

[0141] Fig. 19 is a cross-section of a subassembly 170 comprising the cap 150 and the cap cover 156.

[0142] The cap cover 156 is arranged coaxial with and inside the cap 150. The cap cover 156 comprises the cover structure 23 arranged in a proximal opening 20 of the cap 150. The proximally facing surface 11 of the cap 150 can engage with the distally facing surface 27 of the cap cover 156 when the cap 150 is moved proximally with respect to the cap cover 156 for removal of the cap 150 from the medicament delivery device.

[0143] The compartment 29 is adapted for accommodating a removable needle shield. The radially inwards extending protrusions 31 of the cap cover 156 engages with a distal end of the removable needle shield when the cap cover 156 moves proximally, like the above discussed embodiments.

[0144] The radially inwards extending structure 52 of the cap 150 is arranged distally with respect to the cover structure 23 of the cap cover 156 and protrudes radially inwards into the space 29 or the opening 36 such that an available escape diameter of the opening 36 is reduced to a diameter less than a diameter of the removable needle shield. This means that if the removeable needle shield is removed from the syringe, it cannot escape out from the compartment 29 through the opening 36.

[0145] The radially inwards extending structure 152 is arranged proximally relative to the removable needle shield to prevent it from escaping through the proximal opening 36 or even to reach to the opening 36. In other words, the distally facing surface 160 of the radially inwards extending structure 152 is configured to engage with a proximal surface of the removable needle shield. Embodiments of the present disclosure may be applied to various medicament delivery devices. In one possible implementation, the medicament delivery maybe an autoinjector.

[0146] A medicament delivery device (such as an autoinjector) may generally include various other components. For example, a sensor unit which may recognize medicament delivery events, such as the needle inserted into an attachment portion of e.g., a pad, injection started, and medicament delivery operation ends, a memory unit which is configured to store the recorded data during the medicament delivery operation, a connectivity unit configured to transmit the stored data to a smart device or the network directly, a processing unit configured to control the entire system and processes the data before transmitting it, and / or user interface units that are configured to provide feedback to the patient, such as status LEDs, haptic, and / or audio feedback.

[0147] When the medicament delivery device is placed into the attachment portion, the sensors inside of the pad are configured to recognize the event and give feedback to the patient via haptic / visual or audio elements.

[0148] When the medicament delivery finishes, the sensors are configured to recognize the event and give feedback to the patient again. Further, the collected data is stored in the memory unit and may be transmitted to the smart device / network via the connectivity unit after the medicament delivery event finishes.

[0149] The sensor can be one of or the combination of the following: a mechanical switch, a Hall-effect sensor, an accelerometer.

[0150] The mechanical switch, hall-effect sensor, or accelerometer can be used for detection of the insertion of a needle into an injection port.

[0151] The accelerometer can be used for detecting medicament delivery events.

[0152] Possible wireless communication methods include Bluetooth and Cellular Networks. Bluetooth connectivity requires a smart device to transmit the stored data to the network and it requires a pairing action between the pad and the smart device before being able to use the supporting pad in case of 2-way connection. But it’s a cheaper alternative and it requires less space on PCB. A i-way connection does not require pairing.

[0153] The cellular network does not require any pairing process, it can be used as a plug-n-play device, no prior setup is needed, but it’s more expensive and it requires more space on PCB.

[0154] Depending on the requirements of the product any of those two technologies can be used.

[0155] Such processing units or processing circuitry may comprise a logic circuit or control unit including a microprocessor, microcontroller, programmable digital signal processor or another programmable device. The processing circuitry may also, or instead, each include an application specific integrated circuit, a programmable gate array or programmable array logic, a programmable logic device, or a digital signal processor. Where the processing circuitry includes a programmable device such as the microprocessor, microcontroller or programmable digital signal processor mentioned above, the processor may further include computer executable code that controls operation of the programmable device.

[0156] The medicament delivery devices described herein can be used for the treatment and / or prophylaxis of one or more of many different types of disorders. Exemplary disorders include, but are not limited to: rheumatoid arthritis, inflammatory bowel diseases (e.g. Crohn’s disease and ulcerative colitis), hypercholesterolaemia, diabetes (e.g. type 2 diabetes), psoriasis, migraines, multiple sclerosis, anaemia, lupus, atopic dermatitis, asthma, nasal polyps, acute hypoglycaemia, obesity, anaphylaxis and allergies. Exemplary types of drugs that could be included in the medicament delivery devices described herein include, but are not limited to, antibodies, proteins, fusion proteins, peptibodies, polypeptides, pegylated proteins, protein fragments, protein analogues, protein variants, protein precursors, and / or protein derivatives. Exemplary drugs that could be included in the medicament delivery devices described herein include, but are not limited to (with non-limiting examples of relevant disorders in brackets): etanercept (rheumatoid arthritis, inflammatory bowel diseases (e.g. Crohn’s disease and ulcerative colitis)), evolocumab (hypercholesterolaemia), exenatide (type 2 diabetes), secukinumab (psoriasis), erenumab (migraines), alirocumab (rheumatoid arthritis), methotrexate (amethopterin) (rheumatoid arthritis), tocilizumab (rheumatoid arthritis), interferon beta-ia (multiple sclerosis), sumatriptan (migraines), adalimumab (rheumatoid arthritis), darbepoetin alfa (anaemia), belimumab (lupus), peginterferon beta-ia' (multiple sclerosis), sarilumab (rheumatoid arthritis), semaglutide (type 2 diabetes, obesity), dupilumab (atopic dermatitis, asthma, nasal polyps, allergies), glucagon (acute hypoglycaemia), epinephrine (anaphylaxis), insulin (diabetes), atropine and vedolizumab (inflammatory bowel diseases (e.g. Crohn’s disease and ulcerative colitis)). Pharmaceutical formulations including, but not limited to, any drug described herein are also contemplated for use in the medicament delivery devices described herein, for example pharmaceutical formulations comprising a drug as listed herein (or a pharmaceutically acceptable salt of the drug) and a pharmaceutically acceptable carrier. Pharmaceutical formulations comprising a drug as listed herein (or a pharmaceutically acceptable salt of the drug) may include one or more other active ingredients, or may be the only active ingredient present.

[0157] The inventive concept has mainly been described above with reference to a few examples. However, as is readily appreciated by a person skilled in the art, other embodiments than the ones disclosed above are equally possible within the scope of the inventive concept, as defined by the appended claims. In particular, whilst various distinct embodiments have been described with reference to the drawings, it will be appreciated that components of these distinct embodiments maybe interchanged to provide further embodiments.

[0158] Embodiments of the invention are defined in the following clauses. 1. A subassembly (35, 70) of a medicament delivery device (1), which medicament delivery device (1) extends from a proximal end (la) adapted to face an injection site, to a distal end (ib), along a longitudinal axis (102), the subassembly (35, 70) comprising: a cap (5, 50) arrangeable at the proximal end (la) of the medicament delivery device (1) to cover a needle shield (37), a cap cover (21, 56) arranged coaxial with and inside the cap (5, 50), the cap cover (21, 56) comprising a cover structure (23) arranged in a proximal opening (20) of the cap (5, 50), a distally facing surface (27) configured to engage with a proximally facing surface (11) of the cap (5, 50,150) when the cap (5, 50) is moved proximally with respect to the cap cover (21, 56) for removal of the cap (5, 50) from the medicament delivery device (1), a compartment (29) for accommodating a removable needle shield (43), and radially inwards extending protrusions (31) that engage with the distal end (43b) of the removable needle shield (43) when the cap cover (21, 56) moves proximally, wherein the cap (5, 50) comprises at least one radially inwards extending structure (17, 52) that at least partly blocks a path for the removable needle shield (43) out from the compartment (29) of the cap cover (21, 56) such that the removable needle shield (43) remains at least partly in the compartment (29) after removal of the cap (5, 50) from the medicament delivery device (1).

[0159] 2. The subassembly (35) of clause 1, wherein the at least one radially inwards extending structure (17) of the cap (5) is at least one snap arm (17) arranged in a slot (126) of the cap cover.

[0160] 3. The subassembly (35) of clause 2, the snap-arm (17) comprising a radially inwards extending protrusion (19) that engages with the slot (34) of the cap cover (21). 4. The subassembly (35) of clause 3, wherein the at least one snap arm (17) is configured to pinch on the removable needle shield (43) to prevent it from falling out from the compartment (29).

[0161] 5. The subassembly (35) of any one of clause 3-4, comprising two snap arms (17) arranged on opposite sides of the compartment (29).

[0162] 6. The subassembly (35) of clause 5, wherein a distance between the snaparms (17) is less than a diameter of the removable needle shield (43).

[0163] 7. The subassembly (35) of any one of clauses 3-6, wherein the protrusions (19) of the snap-arms (17) are configured to pinch on the removable needle shield (43).

[0164] 8. The subassembly (35) of any one of clauses 2-7, wherein the distally facing surface (27) configured to engage with the proximally facing surface (11) of the cap (5) is part of the cover structure (23).

[0165] 9. The subassembly (70) of clause 1, wherein the at least one radially inwards extending structure (52) of the cap (50) is arranged proximally with respect to the cover structure (23) of the cap cover (56).

[0166] 10. The subassembly (70) of clause 9, wherein the at least one radially inwards extending structure (52) of the cap (50) is the proximal-most part of the subassembly (70).

[0167] 11. The subassembly (70) of any one of clauses 9-10, wherein the cap cover (56) comprises a distally extending hook (63) having a proximally facing surface (65) that engages with a distally facing surface (67) of the cap (50) so that a longitudinal gap (56) between the at least one radially inwards extending structure (52) and the cover structure (23) of the cap cover (56) is maintained larger than a minimum play.

[0168] 12. The subassembly (70) of any one of clauses 9-11, the at least one radially inwards extending structure (52) of the cap (50) extends to a position directly proximal of an opening (36) of the cover structure of the cap cover (56) into the compartment (29).

[0169] 13 The subassembly (70) of any one of clauses 9-12, wherein the radially inwards extending structure (52) at least partly blocks an opening (36) in the cap cover (56) into the compartment (29) where the removable needle shield (43) is located.

[0170] 14 The subassembly (70) of any one of clauses 9-12, wherein the radially inwards extending structure (52) is arranged to reduce an available escape diameter of an opening (36) in the cap cover (56) to a diameter less than a diameter of the removable needle shield (43).

[0171] 15. The subassembly (170) of clause 1, wherein the at least one radially inwards extending structure (52) of the cap (150) is arranged distally with respect to the cover structure (23) of the cap cover (156).

[0172] 16. The subassembly (170) of clause 15, wherein the radially inwards extending structure (52) is arranged to reduce an available escape diameter of an opening (36) in the cap cover (156) to a diameter less than a diameter of the removable needle shield (43).

[0173] 17. The subassembly (170) of any of clauses 15 or 16, wherein the radially inwards extending structure (52) is arranged to engage with a proximal surface of the removable needle shield (43) to prevent it from escaping through a proximal opening (36) in the cap cover (156).

[0174] 18. The subassembly (170) of clause 17, wherein the proximal surface of the removable needle shield (43) is the proximal-most surface of the removable needle shield (43).

[0175] 19. A subassembly (82) of a medicament delivery device (1), which medicament delivery device extends from a proximal end (la) adapted to face an injection site, to a distal end (ib), along a longitudinal axis (102), comprising: a cap (5, 50) arrangeable at a proximal end (la) of the medicament delivery device (1) to cover a needle shield (37), a cap cover (80) arranged coaxial with and inside the cap (5, 50), the cap cover (80) comprising a cover structure (23) arranged in a proximal opening (20) of the cap (5, 50), a distally facing surface (27) configured to engage with a proximally facing surface (11) of the cap (5, 50) when the cap (5, 50) is moved proximally with respect to the cap cover (80) for removal of the cap (5, 50) from the medicament delivery device (1), a compartment (29) for accommodating a removable needle shield (23), and radially inwards extending protrusions (31) that engages with the distal end (43b) of the removable needle shield (43) when the cap cover (80) moves proximally, wherein the cap cover (80) comprises a tubular body (302) forming the compartment, the tubular body (25) comprising a flexible arm (84) fixed at both ends (84a, 84b), the flexible arm (84) is bent radially inwards to hold the removable needle shield (43) in place in the compartment (29).

[0176] 20. The subassembly (82) according to clause 19, where a centre portion (86) of the flexible arm (84) pinches the removable needle shield (43) against the opposite side (88) of the compartment (29).

[0177] 21. The subassembly (82) according to any one of clauses 19-20, wherein one end (84a) of the flexible arm (84) is proximally arranged with respect to the other end (84b) of the flexible arm (84).

[0178] 22. The subassembly (82) according to any one of clauses 19-21, wherein the ends (84a, 84b) of the flexible arm are aligned along an axis parallel with the longitudinal axis (102).

[0179] 123. The subassembly (82) according to any one of clauses 19-22, comprising two flexible arms (84).

[0180] 24. The subassembly (82) according to clause 23, the two flexible arms (84) being arranged on opposite sides of the tubular body (25). 25. A subassembly (90) of a medicament delivery device (1), which medicament delivery device (1) extends from a proximal end (la) adapted to face an injection site, to a distal end (ib), along a longitudinal axis (102), the subassembly (90) comprising: a cap (5, 50) arrangeable at the proximal end (la) of the medicament delivery device (1) to cover a needle shield (37), a cap cover (21, 56) arranged coaxial with and inside the cap (5, 50), the cap cover (21, 56) comprising a cover structure (23) arranged in a proximal opening (20) of the cap (5, 50), a distally facing surface (27) configured to engage with a proximally facing surface (11) of the cap (5, 50) when the cap (5, 50) is moved proximally with respect to the cap cover (21, 56) for removal of the cap (5, 50) from the medicament delivery device (1), a compartment (29) for accommodating a removable needle shield (43), and radially inwards extending protrusions (31) that engage with the distal end (43b) of the removable needle shield (43) when the cap cover (21, 56) moves proximally, and a clip (92) comprising at least one leg (94) that is arranged between the removable needle shield (43) and an inner surface (96) of a wall of the compartment (29), the clip (92) being arranged to squeeze the removable needle shield (43) in a radial inwards direction to hold the removable needle shield (43) in place in the compartment (29).

[0181] 26. The subassembly (90) according to clause 25, wherein the clip (92) is attached to the removable needle shield (120).

[0182] 27. The subassembly (90) according to any one of clauses 25-26, wherein the clip (92) is squeezed by a radially inwards facing wall (96) of the cap cover.

[0183] 28. The subassembly (90) according to any one of clauses 25-27, wherein a diameter of the volume inside the cap cover (56) is tapered such that when the cap cover (56) moves proximally with respect to the clip (92), the clip squeezes harder on the removable needle shield (43).

[0184] 29. The subassembly (90) according to clause 25, where the clip (92) is a C- clip.

[0185] 30. A subassembly (112) of a medicament delivery device (1), which medicament delivery device (1) extends from a proximal end (la) adapted to face an injection site, to a distal end (ib), along a longitudinal axis (102), the subassembly (90) comprising: a cap (110) arrangeable at the proximal end (la) of the medicament delivery device (1) to cover a needle shield (37), a cap cover (114) arranged coaxial with and inside the cap (110), the cap cover (114) comprising a cover structure (23) arranged in a proximal opening (20) of the cap (110), a distally facing surface (27) configured to engage with a proximally facing surface (11) of the cap (110) when the cap (110) is moved proximally with respect to the cap cover (114) for removal of the cap (110) from the medicament delivery device (1), a compartment (29) for accommodating a removable needle shield (43), and radially inwards extending protrusions (31) that engages with the distal end (43b) of the removable needle shield (43) when the cap cover (114) moves proximally, wherein the cap cover (114) comprises a transversal arm (116) on a proximal end (114a) that blocks a pathway of the removable needle shield (43) out from the compartment (31) through an opening (36) of the cover structure (23), the transversal arm (116) being arranged proximal to the opening (36).

[0186] 31. The subassembly (112) according to clause 30, wherein the transversal arm (116) is attached to the cap cover (114) by a hinge (118) on one end of the transversal arm and comprises a hook (120) on the opposite end of the transversal arm (116) that locks under a flange (122) of the cap cover. 32. The subassembly (112) according to clause 31, the cap comprises a proximally extending flange that at least partly covers the hook of the transversal arm when locked to the flange of the cap cover.

[0187] 33. The subassembly (112) according to any one of clauses 30-32, the transversal arm (116) is arranged to intercept the longitudinal axis (102).

[0188] 34. A medicament delivery (1) device comprising the subassembly (35, 70, 82, 90, 112) according to any one of the preceding clauses.

Claims

CLAIMS1. A subassembly (35, 70, 170) of a medicament delivery device (1), which medicament delivery device (1) extends from a proximal end (la) adapted to face an injection site, to a distal end (ib), along a longitudinal axis (102), the subassembly (35, 70) comprising: a cap (5, 50, 150) arrangeable at the proximal end (la) of the medicament delivery device (1) to cover a needle shield (37), a cap cover (21, 56, 156) arranged coaxial with and inside the cap (5, 50, 150), the cap cover (21, 56, 156) comprising a cover structure (23) arranged in a proximal opening (20) of the cap (5, 50, 150), a distally facing surface (27) configured to engage with a proximally facing surface (11) of the cap (5, 50, 150) when the cap (5, 50, 150) is moved proximally with respect to the cap cover (21, 56, 156) for removal of the cap (5, 50, 150) from the medicament delivery device (1), a compartment (29) for accommodating a removable needle shield (43), and radially inwards extending protrusions (31) that engage with the distal end (43b) of the removable needle shield (43) when the cap cover (21, 56, 156) moves proximally, wherein the cap (5, 50, 150) comprises at least one radially inwards extending structure (17, 52, 152) that at least partly blocks a path for the removable needle shield (43) out from the compartment (29) of the cap cover (21, 56, 156) such that the removable needle shield (43) remains at least partly in the compartment (29) after removal of the cap (5, 50, 150) from the medicament delivery device (1).

2. The subassembly (35) of claim 1, wherein the at least one radially inwards extending structure (17) of the cap (5) is at least one snap arm (17) arranged in a slot (126) of the cap cover.

3. The subassembly (35) of claim 2, the snap-arm (17) comprising a radially inwards extending protrusion (19) that engages with the slot (34) of the cap cover (21).

4. The subassembly (35) of any one of claims 3, wherein the protrusions (19) of the snap-arms (17) are configured to pinch on the removable needle shield (43).

5. The subassembly (35) of any one of claims 2-4, wherein the distally facing surface (27) configured to engage with the proximally facing surface (11) of the cap (5) is part of the cover structure (23).

6. The subassembly (70) of claim 1, wherein the at least one radially inwards extending structure (52) of the cap (50) is arranged proximally with respect to the cover structure (23) of the cap cover (56).

7. The subassembly (70) of claim 6, wherein the at least one radially inwards extending structure (52) of the cap (50) is the proximal-most part of the subassembly (70).

8. The subassembly (70) of any one of claims 6-7, wherein the cap cover (56) comprises a distally extending hook (63) having a proximally facing surface (65) that engages with a distally facing surface (67) of the cap (50) so that a longitudinal gap (56) between the at least one radially inwards extending structure (52) and the cover structure (23) of the cap cover (56) is maintained larger than a minimum play.

9. The subassembly (70) of any one of claims 6-8, the at least one radially inwards extending structure (52) of the cap (50) extends to a position directly proximal of an opening (36) of the cover structure of the cap cover (56) into the compartment (29).

10. The subassembly (70) of any one of claims 6-9, wherein the radially inwards extending structure (52) at least partly blocks an opening (36) in the cap cover (56) into the compartment (29) where the removable needle shield (43) is located.

11. The subassembly (70) of any one of claims 6-10, wherein the radially inwards extending structure (52) is arranged to reduce an available escapediameter of an opening (36) in the cap cover (56) to a diameter less than a diameter of the removable needle shield (43).

12. The subassembly (170) of claim 1, wherein the at least one radially inwards extending structure (152) of the cap (150) is arranged distally with respect to the cover structure (23) of the cap cover (156).

13. The subassembly (170) of claim 12, wherein the radially inwards extending structure (152) is arranged to reduce an available escape diameter of an opening (36) in the cap cover (156) to a diameter less than a diameter of the removable needle shield (43).

14. The subassembly (170) of any of claims 12 or 13, wherein the radially inwards extending structure (152) is arranged to engage with a proximal surface of the removable needle shield (43) to prevent it from escaping through a proximal opening (36) in the cap cover (156).

15. The subassembly (170) of claim 14, wherein the proximal surface of the removable needle shield (43) is the proximal-most surface of the removable needle shield (43).

Images