Bicistronic gene expression systems and methods of use

WO2025240607A8PCT designated stage Publication Date: 2026-06-18REJUVENATE BIO INC
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
REJUVENATE BIO INC
Filing Date
2025-05-14
Publication Date
2026-06-18

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Abstract

Provided herein are polynucleotides comprising at least two coding sequences for expression of coding sequences of interest in a cell and two transcriptional regulatory elements. The transcriptional regulatory elements may be tissue specific. Also provided are vectors, recombinant viral genomes, and recombinant virus compositions comprising said polynucleotides, as well as associated methods.
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