Evaluation method and estimation method

The method evaluates and classifies internal and external indicators to predict future skin changes, offering personalized recommendations for improving skin condition, addressing the inconsistency in existing methods and enhancing user satisfaction.

WO2025244052A1PCT designated stage Publication Date: 2025-11-27SHISEIDO CO LTD
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Patent Information

Application Number
PCT/JP2025/018338
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-05-22
Filing Date
2025-05-21
Publication Date
2025-11-27

AI Technical Summary

Technical Problem

Existing methods fail to provide personalized and accurate predictions of future skin changes and effective measures to prevent or improve skin condition based on individual mental and physical factors, leading to inconsistent and unsatisfactory recommendations for skin care and lifestyle adjustments.

Method used

A method for evaluating skin condition by classifying internal indicators and external substance indicators, assessing mental and physical levels, and estimating future skin changes using a decision tree or machine learning algorithm, providing personalized recommendations for improving skin condition.

Benefits of technology

Enables comprehensive and accurate estimation of future skin changes, allowing for personalized and effective measures to improve skin condition, increasing user satisfaction and reliability of recommendations.

✦ Generated by Eureka AI based on patent content.

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Abstract

Provided is a method that enables fundamental intervention to prevent deterioration of a future skin condition, by estimating how the skin of an individual will change in the future on the basis of latent functions in the body, through skin diagnosis. An evaluation method according to one embodiment of the present invention is for evaluating mind and body level with respect to a skin condition. The method includes a step of classifying an index in the body, an index of a substance released from the body to the outside of the body, and / or a body language index on the basis of a change due to a stimulus from the outside and a persistence of the change.
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Description

Evaluation and estimation methods

[0001] The present invention relates to evaluation and estimation methods.

[0002] The condition of skin varies from person to person depending on factors such as age, living environment (such as ultraviolet rays), and lifestyle habits (such as diet and exercise). It is generally said that ageing leads to an increase in age spots and wrinkles. The rate at which skin aging progresses varies from user to user depending on various factors such as the user's body composition, immunity, and blood flow.

[0003] For example, one method for diagnosing signs of aging is to evaluate the level of gene expression (Patent Document 1).

[0004] Japanese Patent Application Laid-Open No. 2022-69443

[0005] Users are very interested in how their skin will change in the future and what kind of skin care, diet, exercise, etc. they should adopt to prevent deterioration of their skin or improve their skin.

[0006] Therefore, skin diagnosis is required to predict how one's skin will change in the future and to take fundamental measures based on the underlying functions in the body that can prevent future skin deterioration.

[0007] An evaluation method according to one embodiment of the present invention is a method for evaluating the physical and mental effects of skin condition, and includes a step of classifying internal indicators, indicators of substances released from the body to the outside, and / or body language indicators based on changes due to external stimuli and the persistence of such changes.

[0008] The present invention can identify internal indicators that indicate potential physical and mental functions that affect skin condition and / or indicators of substances released from the body to the outside, and from these indicators it is possible to estimate the degree and direction of future skin changes.

[0009] FIG. 1 is a sequence diagram of a method according to a first embodiment of the present invention. FIG. 2 is an example of classification of indices according to an embodiment of the present invention. FIG. 3 is a diagram for explaining evaluation of mental and physical extent according to an embodiment of the present invention. FIG. 4 is a diagram for explaining evaluation of mental and physical extent according to an embodiment of the present invention. FIG. 5 is a diagram for explaining evaluation of mental and physical extent according to an embodiment of the present invention. FIG. 6 is a sequence diagram of a method according to a second embodiment of the present invention. FIG. 7 is a display example of an estimation result according to an embodiment of the present invention. FIG. 8 is a display example of an estimation result according to an embodiment of the present invention. FIG. 9 is a display example of an estimation result according to an embodiment of the present invention. FIG. 10 is a sequence diagram of a method according to a third embodiment of the present invention. FIG. 11 is a table of calculation of classification grades and directionality and degree of change N years from now according to an embodiment of the present invention. FIG. 12 is a sequence diagram of a method according to a fourth embodiment of the present invention. FIG. 13 is a diagram for explaining momentum of skin change over time according to an embodiment of the present invention. FIG. 14 is a diagram for explaining future skin conditions according to an embodiment of the present invention. FIG. 15 is a display example of an estimation result according to an embodiment of the present invention. FIG. 16 is a diagram illustrating an overall configuration according to an embodiment of the present invention. FIG. 17 is a diagram illustrating the functional configuration of an estimation device according to an embodiment of the present invention. FIG. 18 is a diagram illustrating the hardware configuration of an estimation device according to an embodiment of the present invention.

[0010] Hereinafter, an embodiment of the present invention will be described with reference to the drawings.

[0011] First Embodiment FIG. 1 is a sequence diagram of a method (a method for evaluating the mental and physical effects of skin condition) according to a first embodiment of the present invention.

[0012] In step 11 (S11), actual measured values ​​of the subject's internal indicators and / or indicators of substances released from the body to the outside are obtained. The actual measured values ​​of the internal indicators and / or indicators of substances released from the body to the outside can be values ​​obtained using a general measuring device suitable for the indicators, evaluation values ​​obtained from a medical interview, etc. The timing of the actual measurement of the internal indicators and / or indicators of substances released from the body to the outside can be the same or different from the timing of classifying the indicators. For example, the results of a health check, measurements taken by other measuring institutions or personal wearable devices, estimated values ​​from images captured by a camera on a mobile device, self-reported values, and predicted values ​​or extrapolated values ​​from these can also be used.

[0013] For example, indicators of the body and / or indicators of substances released from the body to the outside include height, weight, BMI, grip strength, bone density, muscle mass, lean body mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR value, movement frequency, hearing, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, immunity, inflammation, oxidation, brain waves, minerals, vitamins, walking posture, facial distortion, taste, vision, blood vessel shape, etc.

[0014] The intestinal environment can be assessed using, for example, the amount of IgA in stool or blood, a medical interview regarding the color, shape, consistency and frequency of stool, images of stool, one or more values ​​of the type, amount and diversity of intestinal bacteria, and evaluation results.

[0015] Immunity and inflammation can be measured, for example, by quantifying related proteins and using the related proteins as actual measured values.

[0016] Oxidation can be estimated from saliva or related indicators, or the amount of oxidizing and antioxidant factors in the blood can be quantified, and the amount of oxidizing and antioxidant factors can be used as an actual measurement value.

[0017] The BMI can be an actual measurement value such as a value calculated from a weight scale and a height gauge.

[0018] The autonomic nervous system can measure pulse waves, and the calculated values ​​of low frequency information (LF) and high frequency information (HF) as well as the measured values ​​of the autonomic nervous system state through an app for measuring the autonomic nervous system can be used as actual measurements.

[0019] Actual glycation values ​​can be calculated using a glycation measuring device that can measure through the skin of the arm, measurement results of HbA1C and glucoalbumin in the blood, or estimated glycation values ​​through the tongue, etc.

[0020] The amount of sebaceous gland secretions can be measured as the amount of inflammatory lipids in sweat, the amount of aging substances, etc.

[0021] Skin gases can be collected by placing the palm of the hand in a specific gas collection bag, and skin gas indicators can be identified by combining gas chromatography and mass spectrometry, and the calculated quantitative values ​​can be used as actual measured values.

[0022] The timing of measurement may be changed depending on the nature of change and continuity. For example, in the case of BMI, if there is no direct influence such as diet or disease, measurement may be performed once every six months, and the same measurement value may be used for six months.

[0023] Note that step 12 and step 11 may be reversed.

[0024] In step 12 (S12), the internal indicators and / or the indicators of substances released from the body to the outside are classified based on the changes caused by external stimuli and the persistence of the changes, which are related to the skin condition. Figure 2 shows an example of the classification of indicators according to one embodiment of the present invention. Note that a rapid change is also referred to as a large change, and a slow change is also referred to as a small change.

[0025] [Classification of Intracorporeal Indicators and / or Indicators of Substances Released from the Body to the Outside] Here, classification of intracorporeal indicators and / or indicators of substances released from the body to the outside will be described. The classification of intracorporeal indicators and / or indicators of substances released from the body to the outside is determined by the degree of change due to external stimuli (for example, it may be divided into two categories: large (i.e., fast) and small (i.e., slow), or may be divided into three or more categories such as large, medium, and small), or the presence or absence of change, and whether or not the change is persistent. Note that changes due to external stimuli include changes due to environmental stress, psychological stress, lifestyle habits, etc. Specifically, environmental stress includes ultraviolet rays, dryness, friction, temperature and humidity, pollen, atmospheric fine particles (PM2.5), light such as blue light, etc.; psychological stress includes stress caused by changes in interpersonal relationships, work, further education, home environment, etc.; lifestyle habits include poor diet, bathing habits, lack of sleep, lack of exercise, etc.; and changes due to external stimuli may be any change caused by any stimulus.

[0026] The internal indicators, indicators of substances released from the body to the outside, and / or body language indicators are one or more of the following: small (i.e., slow) changes in response to external stimuli and the changes are persistent; large (i.e., fast) changes in response to external stimuli and the changes are not persistent; large (i.e., fast) changes in response to external stimuli and the changes are persistent; or small (i.e., slow) changes in response to external stimuli and the changes are not persistent. Examples of substances released from the body to the outside include skin gases and voiceprints. Examples of body language indicators include walking speed, walking posture, movement frequency, and facial distortion.

[0027] For example, indicators that change little (i.e., slowly) in response to external stimuli (external actions) and whose changes are sustained include one or more of height, weight, BMI, grip strength, bone density, muscle mass, lean mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing.Indicators that change greatly (i.e., quickly) in response to external stimuli and whose changes are not sustained include one or more of brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio. - Indicators that change significantly (i.e., quickly) in response to external stimuli and whose changes are sustained include one or more of the following: immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone. - Indicators that change only slightly (i.e., slowly) in response to external stimuli and whose changes are not sustained include one or more of the following: metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen.

[0028] In step 13 (S13), the mental and physical level of the skin condition is evaluated. Specifically, the internal indicators and / or indicators of substances released from the body to the outside are classified, and the mental and physical level is evaluated based on the actual measured values ​​of the indicators belonging to the same classification, grades obtained by dividing the actual measured values ​​according to the distribution of past measurements and the degree of impact on the skin, etc., and then the levels are compared between different classifications. For example, if the mental and physical level is evaluated so that the mental and physical state has a potentially positive effect on the skin, the classification with a higher mental and physical level can be evaluated as a group of indicators that have a positive effect on the subject's skin. If the evaluations are equal, it is desirable to prioritize an indicator classification that shows little change due to external stimuli (external action) and that shows persistent change. However, the prioritized classification can be changed depending on the user's characteristics and situation. For example, if the user desires some kind of change quickly, it is desirable to prioritize an indicator classification that shows large change due to external stimuli and that shows persistent change. If the user is already engaged in work with an irregular work schedule, it is possible to lower the priority of an indicator classification that shows large change due to external stimuli but does not show persistent change. Furthermore, measures to further increase the index of high mental and physical condition or measures to increase the index of low mental and physical condition may be proposed.

[0029] FIG. 3 is a diagram illustrating the evaluation of physical and mental conditions according to one embodiment of the present invention. Indicators belonging to each category are measured, and the measured values ​​are divided into, for example, 10 grades. The average value of each index grade for each category is calculated, and the average value is then calculated. The calculated average values ​​are compared, and the strengths and weaknesses of the potential physical and mental abilities (influence levels) are determined based on the magnitude relationship of the average values. The number of grades and the number of grades may be the same or different for each category (for example, axis, circulation, quality), and are determined appropriately. Two or more indexes within a category may be used, or only one index may be used. In the case of a single index, the average value for each category is not calculated, and the grade of that single index is used.

[0030] While Figure 3 shows the results of one measurement of each index, the index may be measured intermittently multiple times or at least once over a certain period (seconds, minutes, hours, days, etc.). In this case, the change in the measurement results over that period may be calculated from each measurement result, and the resulting grade may be used to evaluate the level of each category. Alternatively, the average value of each measurement value or any one of the measurement values ​​may be used to grade the level of each category. The number of times and timing of measurement for each index may be determined according to the identification of the index, etc.

[0031] As shown in Figure 4, after evaluating the level of each category and before calculating the level of each category (e.g., a comparison such as B < A < C), two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., classification of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 4, index X corresponds to muscle mass, and index Y corresponds to albumin. Since evaluation between categories can be performed by referring to the results of evaluation between indices, more accurate recommendations are possible.

[0032] As shown in Figure 5, after determining strengths and weaknesses, two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., categories of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 5, indicator X corresponds to muscle mass, and indicator Y corresponds to albumin. In addition to evaluating strengths and weaknesses, evaluation can also be performed between specific indices, thereby increasing the accuracy of recommendations for improving future skin, body, and mental conditions.

[0033] [Physical and mental level] The physical and mental level is one or more of the following: the level of ability to have a positive effect on the skin through the body and mind, the level of ability to develop the skin in a positive direction through the body and mind, and the level of ability to produce good skin through the body and mind. Note that it may also be the level of ability to improve skin evaluation by a third party through the body and mind.

[0034] This method of assessing the mental and physical condition of the user's skin is evaluated from multiple angles using multiple mental and physical indices, which has the advantage of allowing for comprehensive and potential calculation of the user's skin. However, while comprehensive, the complex relationships between the indices make it difficult for users to prioritize. The lack of prioritization can make it difficult to understand one's own potential condition and to determine whether it is good or bad. Therefore, the section that classifies the mental and physical indices, corresponding to the classification unit 102 described below, is configured to classify the values ​​indicating the degree of the user's skin-related mental and physical condition based on the ease of change and the persistence of that change, and evaluate the level of each classification. In other words, for example, if a user understands their potential condition based on their mental and physical condition and desires good skin in the future, they can prioritize methods for achieving good skin and indices for achieving good skin, thereby enabling them to take measures with a high degree of satisfaction while maintaining comprehensive judgment of whether it is good or bad. This increases the user's satisfaction, reliability, selectivity, and feasibility of recommendations and solutions, such as skin care, lifestyle, and dietary improvements, that improve their potential condition.

[0035] Furthermore, in the method for evaluating the physical and mental condition, by measuring the indicators multiple times or for a certain period of time, it is possible to evaluate the grade and strengths and weaknesses based on the changes in the indicators. Furthermore, in the method of Figure 4, it is possible to perform an evaluation between categories by referring to the results of the evaluation between indicators, which enables more accurate recommendations. Furthermore, in the method of Figure 5, it is possible to perform an evaluation between specific indicators in addition to the evaluation of strengths and weaknesses, which increases the accuracy of recommendations for improving future skin, body, and mental conditions.

[0036] In step 14 (S14), measures are proposed to improve future skin conditions (for example, if there is a high possibility of skin deterioration, reduce the degree of change or change the direction of change, and if there is no change, maintain the current condition or lead to change in a better direction) depending on the results of the mental and physical condition assessment. For example, measures include cosmetics, extracts from foods, beauty treatments, lifestyle habits such as eating habits, exercise habits, and sleep habits. Measures are proposed to further increase the indicators of high mental and physical conditions, or measures to increase the indicators of low mental and physical conditions.

[0037] [Skin Condition] Skin condition mainly includes skin shape, color, and internal skin condition. It is known that skin condition changes due to environmental stress, psychological stress, and lifestyle habits. However, skin shape, color, and internal skin condition do not necessarily change at the same time or in the same direction. The presence or absence of change and the direction of change may differ depending on the skin index.

[0038] In particular, it is believed that wrinkles, age spots, and other changes in skin over time worsen uniformly. However, the amount and severity of wrinkles and age spots vary greatly from person to person. Some people have more or less than the average for their actual age. Examples include moisture, complexion, clarity, firmness, wrinkles, age spots, sagging, dullness, and pores. ・When skin condition is moist, the skin index is one or more of the following: moisture content, amount of water evaporation, permeability to substances, number of textures, uniformity of texture, and size of keratinocytes. ・When skin condition is complexion, the skin index is one or more of the following: a* value, area of ​​redness, unevenness of color (unevenness of redness), and intensity of redness. ・When skin condition is transparency, the skin index is one or more of the following: transparency, brightness, and L* value. - If the skin condition is firm, the skin index is one or more of elasticity, viscosity, softness, elongation rate, return rate after stretching, and return speed after stretching. - If the skin condition is wrinkles, the skin index is one or more of wrinkle area, number of wrinkles, maximum wrinkle depth, variance of multiple wrinkle areas, and change in skin surface shape. - If the skin condition is spots, the skin index is one or more of number of spots, spot density, spot area, maximum spot area, and maximum spot density. - If the skin condition is sagging, the skin index is one or more of change in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines.

[0039] Second Embodiment FIG. 6 is a sequence diagram of a method (method for estimating future skin conditions) according to a second embodiment of the present invention.

[0040] In step 21 (S21), actual measured values ​​of the subject's internal indicators and / or indicators of substances released from the body to the outside are obtained. The actual measured values ​​of the internal indicators and / or indicators of substances released from the body to the outside can be values ​​obtained using a general measuring device suitable for the indicators, evaluation values ​​obtained from a medical interview, etc. The timing of the actual measurement of the internal indicators and / or indicators of substances released from the body to the outside can be the same or different from the timing of classifying the indicators. For example, the results of a health check, measurements taken by other measuring institutions or personal wearable devices, estimated values ​​from images captured by a camera on a mobile device, self-reported values, and predicted values ​​or extrapolated values ​​from these can also be used.

[0041] The intestinal environment can be assessed using, for example, the amount of IgA in stool or blood, a medical interview regarding the color, shape, consistency and frequency of stool, images of stool, one or more values ​​of the type, amount and diversity of intestinal bacteria, and evaluation results.

[0042] Immunity and inflammation can be measured, for example, by quantifying related proteins and using the related proteins as actual measured values.

[0043] Oxidation can be estimated from saliva or related indicators, or the amount of oxidizing and antioxidant factors in the blood can be quantified, and the amount of oxidizing and antioxidant factors can be used as an actual measurement value.

[0044] The BMI can be an actual measurement value such as a value calculated from a weight scale and a height gauge.

[0045] The amount of sebaceous gland secretions can be measured as the amount of inflammatory lipids in sweat, the amount of aging substances, etc.

[0046] The actual measured values ​​of the autonomic nervous system can be calculated values ​​of low frequency information (LF) and high frequency information (HF) by measuring the pulse wave, or the measured values ​​of the autonomic nervous system state through an app for measuring the autonomic nervous system. The autonomic nervous system includes, for example, the degree of imbalance between the parasympathetic nervous system and the sympathetic nervous system calculated using the low frequency information (LF) and high frequency information (HF).

[0047] Actual glycation values ​​can be calculated using a glycation measuring device that can measure through the skin of the arm, measurement results of HbA1C and glucoalbumin in the blood, or estimated glycation values ​​through the tongue, etc.

[0048] The timing of measurement may be changed depending on the nature of change and continuity. For example, in the case of BMI, if there is no direct influence such as diet or disease, measurement may be performed once every six months, and the same measurement value may be used for six months.

[0049] Note that step 21 and step 22 may be reversed.

[0050] In step 22 (S22), the internal indicators and / or the indicators of substances released from the body to the outside are classified based on the changes caused by external stimuli and the continuity of the changes, which are related to the skin condition.

[0051] [Classification of Intracorporeal Indicators and / or Indicators of Substances Released from the Body to the Outside] Here, classification of intracorporeal indicators and / or indicators of substances released from the body to the outside will be described. The classification of intracorporeal indicators and / or indicators of substances released from the body to the outside is determined by the degree of change due to external stimuli (for example, it may be divided into two categories: large (i.e., fast) and small (i.e., slow), or may be divided into three or more categories such as large, medium, and small), or the presence or absence of change, and whether or not the change is persistent. Note that changes due to external stimuli include changes due to environmental stress, psychological stress, lifestyle habits, etc. Specifically, environmental stress includes ultraviolet rays, dryness, friction, temperature and humidity, pollen, atmospheric fine particles (PM2.5), light such as blue light, etc.; psychological stress includes stress caused by changes in interpersonal relationships, work, further education, home environment, etc.; lifestyle habits include poor diet, bathing habits, lack of sleep, lack of exercise, etc.; and changes due to external stimuli may be any change caused by any stimulus.

[0052] The internal indicators, indicators of substances released from the body to the outside, and / or body language indicators are one or more of the following: small (i.e., slow) changes in response to external stimuli and the changes are persistent; large (i.e., fast) changes in response to external stimuli and the changes are not persistent; large (i.e., fast) changes in response to external stimuli and the changes are persistent; or small (i.e., slow) changes in response to external stimuli and the changes are not persistent. Examples of substances released from the body to the outside include skin gases and voiceprints. Examples of body language indicators include walking speed, walking posture, movement frequency, and facial distortion.

[0053] For example, indicators that change little (i.e., slowly) in response to external stimuli (external actions) and whose changes are sustained include one or more of height, weight, BMI, grip strength, bone density, muscle mass, lean mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing.Indicators that change greatly (i.e., quickly) in response to external stimuli and whose changes are not sustained include one or more of brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio. - Indicators that change significantly (i.e., quickly) in response to external stimuli and whose changes are sustained include one or more of the following: immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone. - Indicators that change only slightly (i.e., slowly) in response to external stimuli and whose changes are not sustained include one or more of the following: metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen.

[0054] In step 23 (S23), the mental and physical level of the skin condition is evaluated. Specifically, the internal indicators and / or indicators of substances released from the body to the outside are classified, and the mental and physical level is evaluated based on the actual measured values ​​of the indicators belonging to the same classification, grades obtained by dividing the actual measured values ​​according to the distribution of past measurements and the degree of impact on the skin, etc., and then the levels are compared between different classifications. For example, if the mental and physical level is evaluated so that the mental and physical state has a potentially positive effect on the skin, the classification with a higher mental and physical level can be evaluated as a group of indicators that have a positive effect on the subject's skin. If the evaluations are similar, it is desirable to prioritize an indicator classification that shows little change due to external stimuli (external action) and that shows persistent change. However, the prioritized classification can be changed depending on the user's characteristics and situation. For example, if the user desires some kind of change quickly, it is desirable to prioritize an indicator classification that shows large change due to external stimuli and that shows persistent change. If the user is already engaged in work with an irregular work schedule, it is possible to lower the priority of an indicator classification that shows large change due to external stimuli but does not show persistent change.

[0055] FIG. 3 is a diagram illustrating the evaluation of physical and mental conditions according to one embodiment of the present invention. Indicators belonging to each category are measured, and the measured values ​​are divided into, for example, 10 grades. The average value of each index grade for each category is calculated, and the average value is then calculated. The calculated average values ​​are compared, and the strengths and weaknesses of the potential physical and mental abilities (influence levels) are determined based on the magnitude relationship of the average values. The number of grades and the number of grades may be the same or different for each category (for example, axis, circulation, quality), and are determined appropriately. Two or more indexes within a category may be used, or only one index may be used. In the case of a single index, the average value for each category is not calculated, and the grade of that single index is used.

[0056] While Figure 3 shows the results of one measurement of each index, the index may be measured intermittently multiple times or at least once over a certain period (seconds, minutes, hours, days, etc.). In this case, the change in the measurement results over that period may be calculated from each measurement result, and the resulting grade may be used to evaluate the level of each category. Alternatively, the average value of each measurement value or any one of the measurement values ​​may be used to grade the level of each category. The number of times and timing of measurement for each index may be determined according to the identification of the index, etc.

[0057] As shown in Figure 4, after evaluating the level of each category and before calculating the level of each category (e.g., a comparison such as B < A < C), two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., classification of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 4, index X corresponds to muscle mass, and index Y corresponds to albumin. Since evaluation between categories can be performed by referring to the results of evaluation between indices, more accurate recommendations are possible.

[0058] As shown in Figure 5, after determining strengths and weaknesses, two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., categories of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 5, indicator X corresponds to muscle mass, and indicator Y corresponds to albumin. In addition to evaluating strengths and weaknesses, evaluation can also be performed between specific indices, thereby increasing the accuracy of recommendations for improving future skin, body, and mental conditions.

[0059] [Physical and mental level] The physical and mental level is one or more of the following: the level of ability to have a positive effect on the skin through the body and mind, the level of ability to develop the skin in a positive direction through the body and mind, and the level of ability to produce good skin through the body and mind. Note that it may also be the level of ability to improve skin evaluation by a third party through the body and mind.

[0060] This method of assessing the mental and physical condition of the user's skin is evaluated from multiple angles using multiple mental and physical indices, which has the advantage of allowing for comprehensive and potential calculation of the user's skin. However, while comprehensive, the complex relationships between the indices make it difficult for users to prioritize. The lack of prioritization can make it difficult to understand one's own potential condition and to determine whether it is good or bad. Therefore, the section that classifies the mental and physical indices, corresponding to the classification unit 102 described below, is configured to classify the values ​​indicating the degree of the user's skin-related mental and physical condition based on the ease of change and the persistence of that change, and evaluate the level of each classification. In other words, for example, if a user understands their potential condition based on their mental and physical condition and desires good skin in the future, they can prioritize methods for achieving good skin and indices for achieving good skin, thereby enabling them to take measures with a high degree of satisfaction while maintaining comprehensive judgment of whether it is good or bad. This increases the user's satisfaction, reliability, selectivity, and feasibility of recommendations and solutions, such as skin care, lifestyle, and dietary improvements, that improve their potential condition.

[0061] Furthermore, in the method for evaluating the physical and mental condition, by measuring the indicators multiple times or for a certain period of time, it is possible to evaluate the grade and strengths and weaknesses based on the changes in the indicators. Furthermore, in the method of Figure 4, it is possible to perform an evaluation between categories by referring to the results of the evaluation between indicators, which enables more accurate recommendations. Furthermore, in the method of Figure 5, it is possible to perform an evaluation between specific indicators in addition to the evaluation of strengths and weaknesses, which increases the accuracy of recommendations for improving future skin, body, and mental conditions.

[0062] In step 24 (S24), one or more classifications are used to estimate the future skin condition. For example, based on the relationship between the physical and mental condition and the future skin condition, the future skin condition is estimated from the results of the physical and mental condition assessment in S23. For example, a threshold is set for each specific indicator based on the results of the previous studies, and a decision tree (classification or regression) method is used to create multiple branches depending on whether the value is greater or smaller than that threshold. The number of branches is greater than two, with no upper limit. The future skin condition is estimated from the results of a decision tree or machine learning algorithm created in advance. Furthermore, the physical and mental condition is assessed, and measures are proposed based on the results of an analysis of strengths and weaknesses.

[0063] Examples of skin conditions include skin moisture, barrier, complexion, transparency, firmness, pores, wrinkles, age spots, sagging, dullness, uneven skin tone, etc. For example, skin moisture can be estimated from one of the following categories: a small change due to external stimuli and a persistent change, a large change due to external stimuli and a persistent change, or a large change due to external stimuli and a persistent change. Alternatively, the category may be a small change due to external stimuli and a persistent change, or a large change due to external stimuli and a persistent change. Specifically, the estimation is performed using one or more of BMI, stratum corneum SCCA1, glycation, oxidation, grip strength, etc. When using multiple indicators, the estimation can be performed by branching based on the reference value for each indicator.

[0064] For example, the skin color can be estimated from one of the following categories: a category in which the change due to external stimuli is small and the change is persistent, a category in which the change due to external stimuli is large and the change is not persistent, or a category in which the change due to external stimuli is large and the change is persistent. Alternatively, a category in which the change due to external stimuli is small and the change is persistent, or a category in which the change due to external stimuli is large and the change is not persistent may be used. Specifically, the skin color can be estimated using one or more of BMI, stratum corneum SCCA1, oxidation, grip strength, autonomic nerves, etc. When using multiple indicators, the estimation can be performed by branching based on the reference value for each indicator.

[0065] For example, skin transparency can be estimated from one of the following categories: a category in which external stimuli cause little change but the change is persistent, a category in which external stimuli cause great change but the change is not persistent, or a category in which external stimuli cause great change but the change is persistent.It can also be a category in which external stimuli cause great change but the change is not persistent, or a category in which external stimuli cause great change but the change is persistent.Specifically, it can be estimated using one or more of BMI, stratum corneum SCCA1, oxidation, glycation, grip strength, etc.When using multiple indicators, it can also be estimated by branching based on the reference value for each indicator.

[0066] For example, skin firmness can be estimated from one of the following categories: a small change caused by external stimuli and the change is persistent; a large change caused by external stimuli and the change is not persistent; or a large change caused by external stimuli and the change is persistent.It can also be a small change caused by external stimuli and the change is persistent; or a large change caused by external stimuli and the change is persistent.Specifically, it can be estimated using one or more of BMI, stratum corneum SCCA1, oxidation, glycation, grip strength, autonomic nerves, etc.When using multiple indicators, it can also be estimated by branching based on the reference value of each indicator.

[0067] 7 and 8 are examples of displaying estimation results according to one embodiment of the present invention. For example, the following may be displayed: 1. Result data of individual indicators (actual measurement values ​​or grades) - Results of internal indicators - Results of indicators released from the body to the outside - Body language indicators - Mental indicator results 2. Current skin measurement results - Skin results 3. Predicted skin measurement results - Potential skin results - Momentum of skin condition (accelerated aging (momentum in N years): shows standard changes and your own changes. Can be an image, video, or diagram) 4. Classification results of mental and physical level - Type classification - Strengths / weaknesses 5. Counseling - Advice - Solution proposal

[0068] 9 shows an example of a display of the estimation results according to one embodiment of the present invention. The display method may be a diagram chart, or electronic media such as a smart mirror or smart glasses, images, or videos.

[0069] In step 25 (S25), measures are proposed to improve future skin conditions (e.g., reduce the degree of change) according to the results of the estimation of future skin conditions. For example, measures include cosmetics, extracts from foods, meals (meals provided at stores, boxed lunches, etc.), beauty treatments, lifestyle habits such as eating habits, exercise habits, and sleep habits, exercise, etc. The method of providing the contents of the measures is not limited and may be an image, text, etc.

[0070] For example, meal recommendations are displayed as shown in Figure 10. - People with weak A: The index of change due to external stimuli is small and the indicator of the sustainability of the change is weak. For example, when combined with meals, weaknesses: A: The index of change due to stimuli is small and sustained → It contains many elements that enhance the index of supporting the body's axis and foundation. Therefore, as a dietary measure, menus rich in protein and calcium to support the muscles and bones are suggested, and the level of recommendation is presented according to the classification level based on the ingredient content and cooking method based on a specific menu. For example, for lipophilic ingredients, low-temperature cooking is more likely to be recommended for ingredients such as vitamins that are easily broken down by heat, or for people with weak B: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Meal content: Enhances the index of circulation. Specifically, foods containing ginger, Siberian ginseng, etc. are likely to be recommended. - People with weak C: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Dietary content: Ingredients that improve indicators related to the quality of the body, such as inflammation and oxidation, are recommended. For example, kale, which is known for its antioxidant properties, is often recommended.

[0071] [Skin Condition] Skin condition mainly includes skin shape, color, and internal skin condition. It is known that skin condition changes due to environmental stress, psychological stress, and lifestyle habits. However, skin shape, color, and internal skin condition do not necessarily change at the same time or in the same direction. The presence or absence of change and the direction of change may differ depending on the skin index.

[0072] In particular, it is believed that wrinkles, age spots, and other changes in skin over time worsen uniformly. However, the amount and severity of wrinkles and age spots vary greatly from person to person. Some people have more or less than the average for their actual age. Examples include moisture, complexion, clarity, firmness, wrinkles, age spots, sagging, dullness, and pores. ・When skin condition is moist, the skin index is one or more of the following: moisture content, amount of water evaporation, permeability to substances, number of textures, uniformity of texture, and size of keratinocytes. ・When skin condition is complexion, the skin index is one or more of the following: a* value, area of ​​redness, unevenness of color (unevenness of redness), and intensity of redness. ・When skin condition is transparency, the skin index is one or more of the following: transparency, brightness, and L* value. - If the skin condition is firm, the skin index is one or more of elasticity, viscosity, softness, elongation rate, return rate after stretching, and return speed after stretching. - If the skin condition is wrinkles, the skin index is one or more of wrinkle area, number of wrinkles, maximum wrinkle depth, variance of multiple wrinkle areas, and change in skin surface shape. - If the skin condition is spots, the skin index is one or more of number of spots, spot density, spot area, maximum spot area, and maximum spot density. - If the skin condition is sagging, the skin index is one or more of change in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines.

[0073] In this method for estimating skin condition, a plurality of psychosomatic indices are used to estimate the skin condition. In the second embodiment, when the skin condition is estimated using step 23, it is possible to prioritize measures for the user, particularly measures related to lifestyle habits, based on the difference in the degree of classification, which has the advantage of enabling highly accurate recommendations.

[0074] It is known that lifestyle habits affect skin condition. However, the degree of impact and the skin factors they affect vary among multiple users. Currently, the same advice is given, making it difficult to say that it is optimized. Therefore, until now, advice has focused on lifestyle habits that have previously affected a user, depending on the user's experience, or preventative measures have been implemented. However, even for the same user and the same lifestyle, the same skin changes do not necessarily occur when those habits are disrupted, making it difficult to estimate the user's skin condition. This invention estimates skin condition based on the level of mental and physical health, thereby determining the potential mental and physical abilities, strengths, and weaknesses related to skin, regardless of the impact of lifestyle habits or the user's individual characteristics, making skin condition estimation easier. Correction based on lifestyle habits and mental indicators such as drinking, smoking, sleep, and fatigue is also recommended. If correction is implemented, the accuracy of skin condition estimation is likely to increase.

[0075] Furthermore, the second embodiment can be implemented by switching steps 23 and 24. In this case, since the mental and physical conditions of the skin are evaluated from multiple angles using multiple mental and physical indices, there is an advantage that the user's skin can be calculated in a latent and comprehensive manner.

[0076] However, while it is comprehensive, when it comes to users understanding their own physical and mental state, selecting and implementing measures, the fact that there are too many indicators and they are all the same can cause confusion, making it difficult for users to fully understand their own underlying condition, and making judgments about the pros and cons of measures, or choosing the right measures.

[0077] Therefore, the part that classifies the mental and physical indicators, which corresponds to the classification unit 102 described later, is configured to classify the values ​​indicating the degree of the mental and physical state related to the user's skin based on the ease of change and the persistence of that change, and to evaluate the degree of each classification.

[0078] For example, if a user wishes to have good skin in the future, they can understand their potential condition based on their physical and mental state, judge whether it is good or bad, and receive suggested measures based on the priority of the index classification, which will increase their satisfaction.

[0079] This will increase users' satisfaction, trust, and readiness to implement recommendations and solutions, such as skin care, lifestyle, and dietary improvements that will improve underlying conditions.

[0080] <Third embodiment> Fig. 11 is a sequence diagram of a method according to a third embodiment of the present invention (a method for estimating the momentum of skin changes over time (indicating whether or not there will be a change in skin condition over the next N years, the degree of change, and the direction of change)).

[0081] Skin momentum indicates the presence, directionality, and presence or absence of skin changes over time. The greater the positive momentum, the greater the skin changes in the positive direction, and the smaller the positive momentum, the less the skin changes. After classification, skin momentum can be calculated by branching using a decision tree using indicators related to internal indices and / or indicators related to substances released from the body to the outside, or by referring to a table combining the levels of the three physical and mental classifications. Figure 12 is a table showing the classification grade and the calculation of the directionality and degree of change after N years.

[0082] In step 31 (S31), actual measured values ​​of the subject's internal indicators and / or indicators of substances released from the body to the outside are obtained. The actual measured values ​​of the internal indicators and / or indicators of substances released from the body to the outside can be values ​​measured using a general measuring device suitable for the indicators, evaluation values ​​obtained through a medical interview, etc. The timing of the actual measurement of the internal indicators and / or indicators of substances released from the body to the outside can be the same or different from the timing of classifying the indicators. For example, the results of a health check, the results of measurements taken by other measuring institutions or personal wearable devices, estimated values ​​from images captured by a camera on a mobile device, self-reported values, and predicted or extrapolated values ​​from these can also be used.

[0083] The intestinal environment can be assessed using, for example, the amount of IgA in stool or blood, a medical interview regarding the color, shape, consistency and frequency of stool, images of stool, one or more values ​​of the type, amount and diversity of intestinal bacteria, and evaluation results.

[0084] Immunity and inflammation can be measured, for example, by quantifying related proteins and using the related proteins as actual measured values.

[0085] Oxidation can be estimated from saliva or related indicators, or the amount of oxidizing and antioxidant factors in the blood can be quantified, and the amount of oxidizing and antioxidant factors can be used as an actual measurement value.

[0086] The BMI can be an actual measurement value such as a value calculated from a weight scale and a height gauge.

[0087] The amount of sebaceous gland secretions can be measured as the amount of inflammatory lipids in sweat, the amount of aging substances, etc.

[0088] The actual measured values ​​of the autonomic nervous system can be calculated values ​​of low frequency information (LF) and high frequency information (HF) by measuring the pulse wave, or the measured values ​​of the autonomic nervous system state through an app for measuring the autonomic nervous system. The autonomic nervous system includes, for example, the degree of imbalance between the parasympathetic nervous system and the sympathetic nervous system calculated using the low frequency information (LF) and high frequency information (HF).

[0089] Actual glycation values ​​can be calculated using a glycation measuring device that can measure through the skin of the arm, measurement results of HbA1C and glucoalbumin in the blood, or estimated glycation values ​​through the tongue, etc.

[0090] The timing of measurement may be changed depending on the nature of change and continuity. For example, in the case of BMI, if there is no direct influence such as diet or disease, measurement may be performed once every six months, and the same measurement value may be used for six months.

[0091] Note that step 31 and step 32 may be reversed.

[0092] With regard to step 31, the time point at which all actual measurements of substances inside the body and / or released from the body to the outside, which are necessary for estimating the momentum of skin change over time, have been completed, corresponds to the present in Fig. 14. If all actual measurement values ​​are measured when estimating the momentum of skin change over time, the time of actual measurement corresponds to the present in Fig. 14. If the timing of actual measurement of the indices is different, for example, if past health checkup results or the like are used for some indices and actual measurement values ​​at the time of estimating the momentum of skin change over time are used for other indices, the time at which momentum is estimated corresponds to the present in Fig. 14.

[0093] In step 32 (S32), the internal indicators and / or the indicators of substances released from the body to the outside are classified based on the changes caused by external stimuli and the continuity of the changes, which are related to the skin condition.

[0094] [Classification of Intracorporeal Indicators and / or Indicators of Substances Released from the Body to the Outside] Here, classification of intracorporeal indicators and / or indicators of substances released from the body to the outside will be described. The classification of intracorporeal indicators and / or indicators of substances released from the body to the outside is determined by the degree of change due to external stimuli (for example, it may be divided into two categories: large (i.e., fast) and small (i.e., slow), or may be divided into three or more categories such as large, medium, and small), or the presence or absence of change, and whether or not the change is persistent. Note that changes due to external stimuli include changes due to environmental stress, psychological stress, lifestyle habits, etc. Specifically, environmental stress includes ultraviolet rays, dryness, friction, temperature and humidity, pollen, atmospheric fine particles (PM2.5), light such as blue light, etc.; psychological stress includes stress caused by changes in interpersonal relationships, work, further education, home environment, etc.; lifestyle habits include poor diet, bathing habits, lack of sleep, lack of exercise, etc.; and changes due to external stimuli may be any change caused by any stimulus.

[0095] The internal indicators, indicators of substances released from the body to the outside, and / or body language indicators are one or more of the following: small (i.e., slow) changes in response to external stimuli and the changes are persistent; large (i.e., fast) changes in response to external stimuli and the changes are not persistent; large (i.e., fast) changes in response to external stimuli and the changes are persistent; or small (i.e., slow) changes in response to external stimuli and the changes are not persistent. Examples of substances released from the body to the outside include skin gases and voiceprints. Examples of body language indicators include walking speed, walking posture, movement frequency, and facial distortion.

[0096] For example, indicators that change little (i.e., slowly) in response to external stimuli (external actions) and whose changes are sustained include one or more of height, weight, BMI, grip strength, bone density, muscle mass, lean mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing.Indicators that change greatly (i.e., quickly) in response to external stimuli and whose changes are not sustained include one or more of brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio. - Indicators that change significantly (i.e., quickly) in response to external stimuli and whose changes are sustained include one or more of the following: immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone. - Indicators that change only slightly (i.e., slowly) in response to external stimuli and whose changes are not sustained include one or more of the following: metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen.

[0097] In step 33 (S33), the mental and physical level of the skin condition is evaluated. Specifically, the internal indicators and / or indicators of substances released from the body to the outside are classified, and the mental and physical level is evaluated based on the actual measured values ​​of the indicators belonging to the same classification, grades obtained by dividing the actual measured values ​​according to the distribution of past measurements and the degree of impact on the skin, etc., and then the levels are compared between different classifications. For example, if the mental and physical level is evaluated so that the mental and physical state has a potentially positive effect on the skin, the classification with a higher mental and physical level can be evaluated as a group of indicators that have a positive effect on the subject's skin. If the evaluations are equal, it is desirable to prioritize an indicator classification that shows little change due to external stimuli (external action) and that shows persistent change. However, the prioritized classification can be changed depending on the user's characteristics and situation. For example, if the user desires some kind of change quickly, it is desirable to prioritize an indicator classification that shows large change due to external stimuli and that shows persistent change. If the user is already engaged in work with an irregular work schedule, it is possible to lower the priority of an indicator classification that shows large change due to external stimuli but does not show persistent change.

[0098] FIG. 3 is a diagram illustrating the evaluation of physical and mental conditions according to one embodiment of the present invention. Indicators belonging to each category are measured, and the measured values ​​are divided into, for example, 10 grades. The average value of each index grade for each category is calculated, and the average value is then calculated. The calculated average values ​​are compared, and the strengths and weaknesses of the potential physical and mental abilities (influence levels) are determined based on the magnitude relationship of the average values. The number of grades and the number of grades may be the same or different for each category (for example, axis, circulation, quality), and are determined appropriately. Two or more indexes within a category may be used, or only one index may be used. In the case of a single index, the average value for each category is not calculated, and the grade of that single index is used.

[0099] While Figure 3 shows the results of one measurement of each index, the index may be measured intermittently multiple times or at least once over a certain period (seconds, minutes, hours, days, etc.). In this case, the change in the measurement results over that period may be calculated from each measurement result, and the resulting grade may be used to evaluate the level of each category. Alternatively, the average value of each measurement value or any one of the measurement values ​​may be used to grade the level of each category. The number of times and timing of measurement for each index may be determined according to the identification of the index, etc.

[0100] As shown in Figure 4, after evaluating the level of each category and before calculating the level of each category (e.g., a comparison such as B < A < C), two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., classification of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 4, index X corresponds to muscle mass, and index Y corresponds to albumin. Since evaluation between categories can be performed by referring to the results of evaluation between indices, more accurate recommendations are possible.

[0101] As shown in Figure 5, after determining strengths and weaknesses, two or more interrelated indices (e.g., muscle mass and albumin, intestinal environment and sleep) belonging to different categories (i.e., categories of changes due to external stimuli and the persistence of those changes) may be compared. In Figure 5, indicator X corresponds to muscle mass, and indicator Y corresponds to albumin. In addition to evaluating strengths and weaknesses, evaluation can also be performed between specific indices, thereby increasing the accuracy of recommendations for improving future skin, body, and mental conditions.

[0102] [Physical and mental level] The physical and mental level is one or more of the following: the level of ability to have a positive effect on the skin through the body and mind, the level of ability to develop the skin in a positive direction through the body and mind, and the level of ability to produce good skin through the body and mind. Note that it may also be the level of ability to improve skin evaluation by a third party through the body and mind.

[0103] This method of assessing the degree of mental and physical condition has the advantage of being able to comprehensively calculate the user's skin-related mental and physical condition from multiple angles using multiple mental and physical indices. However, while comprehensive, when a user tries to understand their own mental and physical condition, the excessive number of indices can cause confusion, making it difficult for the user to fully understand their own underlying condition, making it difficult to determine whether it is good or bad, and making it difficult to prioritize treatment. Therefore, the section that classifies mental and physical indices, corresponding to the classification unit 102 described below, is configured to classify the user's skin-related mental and physical condition based on values ​​indicating the degree of change and the persistence of that change, and evaluate the degree of each classification. In other words, for example, if a user desires better skin in the future, they can understand their underlying condition based on their mental and physical condition, and can achieve a high level of satisfaction while maintaining a comprehensive judgment of whether it is good or bad. This increases the user's satisfaction and trust in recommendations and solutions, such as skin care, lifestyle, and dietary improvements, that will improve their underlying condition.

[0104] Furthermore, in the method for evaluating the physical and mental condition, by measuring the indicators multiple times or for a certain period of time, it is possible to evaluate the grade and strengths and weaknesses based on the changes in the indicators. Furthermore, in the method of Figure 4, it is possible to perform an evaluation between categories by referring to the results of the evaluation between indicators, which enables more accurate recommendations. Furthermore, in the method of Figure 5, it is possible to perform an evaluation between specific indicators in addition to the evaluation of strengths and weaknesses, which increases the accuracy of recommendations for improving future skin, body, and mental conditions.

[0105] In step 34 (S34), the momentum of skin changes over time is estimated using one or more classifications. For example, based on the relationship between mental and physical condition and the momentum of skin changes over time, the momentum of skin changes over time is estimated as a result of the mental and physical condition evaluation in S33. For example, based on the results of the previous studies, a threshold is set for each specific indicator, and depending on whether the value is greater or smaller than that threshold, a decision tree (classification or regression) method is used to perform multiple branches. The number of branches is greater than two, with no upper limit. The momentum of skin changes over time is estimated from the results of a decision tree or machine learning algorithm created in advance. Furthermore, the mental and physical condition is evaluated, and measures are proposed based on the results of an analysis of strengths and weaknesses.

[0106] 7 and 8 are examples of displaying estimation results according to one embodiment of the present invention. For example, the following may be displayed: 1. Result data of individual indicators (actual measurement values ​​or grades) - Results of internal indicators - Results of indicators released from the body to the outside - Body language indicators - Mental indicator results 2. Current skin measurement results - Skin results 3. Predicted skin measurement results - Potential skin results - Momentum of skin condition (accelerated aging (momentum in N years): shows standard changes and your own changes. Can be shown as images, videos, or diagrams) 4. Classification results of mental and physical level - Type classification - Strengths / weaknesses 5. Counseling - Advice - Solution proposals

[0107] 9 shows an example of displaying the estimation results according to one embodiment of the present invention. The display method may be a diagram chart, or electronic media such as a smart mirror or smart glasses, images, or videos.

[0108] In step 35 (S35), measures are proposed to improve future skin conditions (e.g., reduce the degree of change) based on the results of estimating the momentum of skin changes over time. For example, the measures may include cosmetics, extracts from foods, meals (meals provided at stores, boxed lunches, etc.), beauty treatments, lifestyle habits such as eating habits, exercise habits, and sleep habits, exercise, etc. The method of providing the contents of the measures may be, for example, images or text, and is not limited thereto.

[0109] For example, meal recommendations are displayed as shown in Figure 10. - People with weak A: The index of change due to external stimuli is small and the indicator of the sustainability of the change is weak. For example, when combined with meals, weaknesses: A: The index of change due to stimuli is small and sustained → It contains many elements that enhance the index of supporting the body's axis and foundation. Therefore, as a dietary measure, menus rich in protein and calcium to support the muscles and bones are suggested, and the level of recommendation is presented according to the classification level based on the ingredient content and cooking method based on a specific menu. For example, for lipophilic ingredients, low-temperature cooking is more likely to be recommended for ingredients such as vitamins that are easily broken down by heat, or for people with weak B: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Meal content: Enhances the index of circulation. Specifically, foods containing ginger, Siberian ginseng, etc. are likely to be recommended. - People with weak C: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Dietary content: Ingredients that improve indicators related to the quality of the body, such as inflammation and oxidation, are recommended. For example, kale, which is known for its antioxidant properties, is often recommended.

[0110] [Skin Condition] Skin conditions mainly include wrinkles, age spots, sagging skin, moisture, complexion, transparency, and firmness. While skin condition is known to change due to environmental stress, psychological stress, and lifestyle habits, these skin conditions in particular have been thought to worsen over time. However, the amount and severity of wrinkles and age spots vary greatly from person to person. It is known that some people have more or fewer wrinkles and age spots than average for their actual age. Recently, we measured skin changes in the same individual every three years and found that even for these skin conditions, the direction of change is not uniform, and that skin condition significantly improves in groups with specific physical and mental conditions. This led to the creation of a method that is advantageous in and capable of presenting the momentum of skin condition. By using the present invention, it is possible to indicate the presence, direction, and severity of age-related changes in skin conditions such as wrinkles, age spots, and sagging skin, which have previously been thought to uniformly worsen, and to propose measures to improve momentum.

[0111] For example, the skin condition is one or more of wrinkles, age spots, and sagging. ・When the skin condition is wrinkles, the skin index is one or more of wrinkle area, number of wrinkles, maximum wrinkle depth, variance of multiple wrinkle areas, and morphological change of the skin surface. ・When the skin condition is age spots, the skin index is one or more of number of age spots, age spot density, age spot area, maximum age spot area, and maximum age spot density. ・When the skin condition is sagging, the skin index is one or more of change in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines. ・When the skin condition is moisturized, the skin index is one or more of moisture content, amount of moisture evaporation, substance permeability, number of textures, uniformity of texture, and size of keratinocytes.・When the skin condition is complexion, the skin index is one or more of the following: a* value, redness area, unevenness of color (unevenness of redness), and intensity of redness. ・When the skin condition is transparency, the skin index is one or more of the following: transparency, brightness, and L* value. ・When the skin condition is firmness, the skin index is one or more of the following: elasticity, viscosity, softness, elongation rate, return rate after stretching, and return speed after stretching.

[0112] In this skin estimating method, skin momentum N years from now is estimated using multiple indices within the body and / or indices related to substances released from the body to the outside. In the third embodiment, when recommending skin momentum N years from now using step 33, there is an advantage that the recommendation can be made with high accuracy. Note that the method for estimating skin momentum may be, for example, the directionality and degree of skin change compared with an average value, where the average value is the average value of skin change in the same age group, etc.

[0113] It is known that skin condition after N years varies not only due to direct care such as skin care, but also due to lifestyle habits and personal habits. However, there are few indicators of the body or of substances released from the body that are clearly related to skin condition after N years. By using the present invention, it becomes possible to estimate skin momentum after N years and propose appropriate measures. As a result, it becomes possible to prevent skin deterioration due to aging and obtain skin that does not change with age.

[0114] <Fourth embodiment> Fig. 13 is a sequence diagram of a method according to a fourth embodiment of the present invention (a method for estimating the momentum of skin changes over time (indicating whether or not there will be a change in skin condition over the next N years, the degree of change, and the direction of change)).

[0115] In step 41 (S41), actual measured values ​​of mind and body indices that affect the skin condition after a certain period from the time of measurement are obtained.

[0116] [Mental and physical indices] For example, the mental and physical indices may be one or more of SCCA1, HbA1C, LDL cholesterol, sebum amount, calcium amount, bone density, HDL cholesterol, blood CRP, total protein, intestinal environment, AGEs, and lifestyle habits (meat intake, METS, niacin, etc.). For example, the mental and physical indices may include positive emotions and negative emotions.

[0117] In step 42 (S42), the "momentum of skin change over time" is estimated based on the "actual measured values ​​of mind-body indices that affect skin condition a certain period after measurement" in S41, based on the correlation between the "mental and physical indices that affect skin condition a certain period after measurement" and the "momentum of skin change over time." For example, a decision tree (classification or regression) technique is used to estimate the "momentum of skin change over time" from the "mental and physical indices that affect skin condition a certain period after measurement."

[0118] 7 and 8 are examples of displaying estimation results according to one embodiment of the present invention. For example, the following may be displayed: 1. Result data of individual indicators (actual measurement values ​​or grades) - Results of internal indicators - Results of indicators released from the body to the outside - Body language indicators - Mental indicator results 2. Current skin measurement results - Skin results 3. Predicted skin measurement results - Potential skin results - Momentum of skin condition (accelerated aging (momentum in N years): shows standard changes and your own changes. Can be shown as images, videos, or diagrams) 4. Classification results of mental and physical level - Type classification - Strengths / weaknesses 5. Counseling - Advice - Solution proposals

[0119] 9 shows an example of a display of the estimation results according to one embodiment of the present invention. The display method may be a diagram chart, or electronic media such as a smart mirror or smart glasses, images, or videos.

[0120] In step 43 (S43), measures are proposed to improve future skin conditions (e.g., to reduce the degree of change) based on the results of estimating the momentum of skin changes over time. Examples of such measures include cosmetics, beauty treatments, extracts from foods, diet (meals provided at stores, boxed lunches, etc.), lifestyle habits, exercise, etc.

[0121] For example, meal recommendations are displayed as shown in Figure 10. - People with weak A: The index of change due to external stimuli is small and the indicator of the sustainability of the change is weak. For example, when combined with meals, weaknesses: A: The index of change due to stimuli is small and sustained → It contains many elements that enhance the index of supporting the body's axis and foundation. Therefore, as a dietary measure, menus rich in protein and calcium to support the muscles and bones are suggested, and the level of recommendation is presented according to the classification level based on the ingredient content and cooking method based on a specific menu. For example, for lipophilic ingredients, low-temperature cooking is more likely to be recommended for ingredients such as vitamins that are easily broken down by heat, or for people with weak B: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Meal content: Enhances the index of circulation. Specifically, foods containing ginger, Siberian ginseng, etc. are likely to be recommended. - People with weak C: The index of change due to external stimuli is large and the indicator of the sustainability of the change is weak. → Dietary content: Ingredients that improve indicators related to the quality of the body, such as inflammation and oxidation, are recommended. For example, kale, which is known for its antioxidant properties, is often recommended.

[0122] [Skin Condition] For example, the skin condition is one or more of wrinkles, age spots, and sagging. ・If the skin condition is wrinkles, the skin index is one or more of wrinkle area, number of wrinkles, maximum wrinkle depth, variance of multiple wrinkle areas, and morphological change of the skin surface. ・If the skin condition is age spots, the skin index is one or more of number of age spots, age spot density, age spot area, maximum age spot area, and maximum age spot density. ・If the skin condition is sagging, the skin index is one or more of change in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines. ・If the skin condition is dull, the skin index is one or more of dullness, melanin level, and yellowish dullness. ・If the skin condition is uneven skin tone, the skin index is uneven skin tone.

[0123] In this skin estimating method, skin momentum N years from now is estimated using multiple psychosomatic indices. In the fourth embodiment, when skin momentum N years from now is estimated using step 43, there is an advantage that measures for the user, particularly measures related to future lifestyle habits, can be recommended with high accuracy. Note that the method for estimating skin momentum may be, for example, the direction and degree of skin change compared to an average value, where the average value is the average value of skin changes for people of the same age.

[0124] It is known that lifestyle habits affect skin condition. However, the degree of impact and the skin factors they affect vary among multiple users. Currently, the same advice is given, making it difficult to say that it is optimized. Therefore, until now, advice has focused on lifestyle habits that have previously affected a user, depending on the user's experience, or preventative measures have been implemented. However, even for the same user and the same lifestyle, the same skin changes do not necessarily occur when those habits are disrupted, making it difficult to estimate the user's skin condition. This invention estimates skin condition based on the level of mental and physical health, thereby determining the potential mental and physical abilities, strengths, and weaknesses related to skin, regardless of the impact of lifestyle habits or the user's individual characteristics, making skin condition estimation easier. Correction based on lifestyle habits and mental indicators such as drinking, smoking, sleep, and fatigue is also recommended. If correction is implemented, the accuracy of skin condition estimation is likely to increase.

[0125] Since the mental and physical condition of the skin is evaluated from multiple angles using multiple mental and physical indices, it has the advantage of being able to make latent and comprehensive calculations of the user's skin.

[0126] However, while it is comprehensive, when it comes to users' understanding of their own physical and mental state, the excessive number of indicators can cause confusion, making it difficult for them to fully understand their own underlying condition and making it difficult to judge whether it is good or bad.

[0127] Therefore, the part that classifies the mental and physical indicators, which corresponds to the classification unit 102 described later, is configured to classify the values ​​indicating the degree of the mental and physical state related to the user's skin based on the ease of change and the persistence of that change, and to evaluate the degree of each classification.

[0128] That is, for example, if a user desires good skin in the future, the user can understand his or her potential condition based on the state of his or her mind and body, and can make a highly satisfactory judgment while maintaining comprehensiveness in determining whether it is good or bad.

[0129] This will increase users' confidence in and belief in recommendations and solutions, such as skin care, lifestyle and dietary improvements that will improve underlying conditions.

[0130] The "momentum of skin changes over time" and "future skin condition" will be described with reference to FIGS. 14 and 15.

[0131] 14 is a diagram illustrating the momentum of skin change over time according to an embodiment of the present invention, which indicates whether or not there will be a change in skin condition (e.g., one or more of wrinkles, age spots, sagging, dullness, and uneven skin tone) over the next N years, as well as the degree and direction of the change.

[0132] - If the basis for change is one's current skin, the larger the positive momentum, the larger the positive value of the skin condition N years from now will be compared to the present.- If the basis for change is a vector connecting two points on a coordinate system where the average value of the current general skin condition and the average value of the skin condition N years from now are plotted, the larger the positive momentum, the larger the angle in the positive direction of the vector connecting the average value of the current general skin condition and one's skin condition N years from now will be.- If the basis for change is the difference between the average value of the current general skin condition and the average value of the skin condition N years from now, the larger the positive momentum, the larger the positive value of the difference between one's current skin condition and the skin condition N years from now will be.

[0133] [Future Skin Condition] FIG. 15 is a diagram illustrating a future skin condition according to one embodiment of the present invention. The future skin condition is the skin condition N years from now (e.g., one or more of wrinkles, age spots, sagging, moisture, complexion, transparency, firmness, dullness, and uneven skin tone). For example, the future wrinkle condition is one or more of the following: wrinkle area, number of wrinkles, maximum wrinkle depth, variance of multiple wrinkle areas, and morphological change of the skin surface N years from now. For example, the future age spot condition is one or more of the following: number of age spots, age spot density, age spot area, maximum age spot area, and maximum age spot density N years from now. For example, the future sagging condition is one or more of the following: change in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines N years from now. For example, the future moisture state is one or more of the following after N years: moisture content, moisture evaporation rate, substance permeability, number of textures, texture uniformity, and size of keratinocytes. For example, the future complexion state is one or more of the following after N years: a* value, redness area, uneven skin tone (unevenness of redness), and intensity of redness. For example, the future transparency state is one or more of the following after N years: transparency, brightness, and L* value. For example, the future firmness state is one or more of the following after N years: elasticity, viscosity, softness, elongation, return rate after stretching, and speed of return to original state after stretching. For example, the future dullness state is one or more of the following after N years: dullness, melanin value, and yellowish dullness. For example, the future uneven skin tone state is uneven skin tone after N years.

[0134] The future skin condition of FIG. 15 may be shown as a facial image, facial video, or facial illustration. For example, as shown in FIG. 16 , the skin condition of the present and the future several years and several decades from now is shown. There is no limitation on how many years from now an image or video is shown. Furthermore, since the future skin condition changes depending on the influence of lifestyle habits, environment, etc., the future skin condition may be shown separately for when a lifestyle is disrupted and when a desirable lifestyle is maintained, for example.

[0135] <Overall Configuration> FIG. 17 is a diagram showing the overall configuration according to one embodiment of the present invention.

[0136] Configuration Example 1 The system 1 includes an estimation device 10 and an index value measurement device 20. Each of these will be described below.

[0137] <<Estimation Device>> The estimation device 10 can execute some or all of the methods of the first to fourth embodiments. For example, the estimation device 10 is a personal computer, a tablet, a smartphone, or the like.

[0138] <<Index Value Measurement Device>> The index value measurement device 20 is a device that measures the values ​​of various indexes. There may be two or more index measurement devices. Furthermore, when transmitting to the estimation device 10, actual measured values ​​of the multiple measurement devices may be integrated via another terminal.

[0139] [Configuration Example 2] The system 1 includes an estimation device 10, a terminal 11, and an index value measurement device 20. Each of these will be described below.

[0140] <<Estimation Device>> The estimation device 10 can execute some or all of the methods of the first to fourth embodiments. For example, the estimation device 10 is a server or the like made up of one or more computers.

[0141] <<Terminal>> The terminal 11 transmits data measured by the index value measurement device 20 to the estimation device 10. The terminal 11 also displays data received from the estimation device 10. Note that the terminal 11 may execute part of the processing of the estimation device 10 described in this specification. For example, the terminal 11 is a personal computer, a tablet terminal, a smartphone, smart glasses, etc.

[0142] <<Index Value Measurement Device>> The index value measurement device 20 is a device that measures the values ​​of various indexes.

[0143] The estimation device 10 or the terminal 11 may have the function of the index value measurement device 20 .

[0144] 18 is a diagram showing the functional configuration of an estimation device 10 according to an embodiment of the present invention. The estimation device 10 includes an acquisition unit 101, a classification unit 102, an evaluation unit 103, an estimation unit 104, and a proposal unit 105. The estimation device 10 also functions as the acquisition unit 101, the classification unit 102, the evaluation unit 103, the estimation unit 104, and the proposal unit 105.

[0145] The acquisition unit 101 acquires values ​​of various indicators of the subject 30 (for example, actual measured values ​​of indicators inside the body and / or indicators of substances released from the body to the outside, and actual measured values ​​of mental and physical indicators that affect the skin condition a certain period of time after measurement).

[0146] The classification unit 102 classifies the indicators inside the body and / or the indicators of substances released from the body to the outside based on the change caused by an external stimulus and the continuity of the change.

[0147] The evaluation unit 103 evaluates the mental and physical level of the skin condition. The evaluation unit 103 classifies the indices of the inside of the body and / or the indices of substances released from the inside of the body to the outside, and evaluates the mental and physical level based on the actual measured values ​​of the indices belonging to the same classification. The evaluation unit 103 classifies the indices of the inside of the body and / or the indices of substances released from the inside of the body to the outside, and evaluates the mental and physical level based on the actual measured values ​​of the indices belonging to the same classification, and compares the levels between different classifications.

[0148] The estimation unit 104 estimates future skin conditions using one or more classifications of indices of internal body conditions and / or indices of substances released from the body to the outside. The estimation unit 104 estimates momentum of skin changes over time using one or more classifications of indices of internal body conditions and / or indices of substances released from the body to the outside. The estimation unit 104 estimates momentum of skin changes over time based on actual measured values ​​of mind-body indices that affect the skin condition a certain period after the time of measurement.

[0149] The proposing unit 105 proposes measures to improve future skin condition (displaying the measures on the estimation device 10 or the terminal 11).

[0150] 19 is a diagram showing the hardware configuration of the estimation device 10 according to one embodiment of the present invention. The same applies to the terminal 11.

[0151] The estimation device 10 can include a control unit 1001, a main memory unit 1002, an auxiliary memory unit 1003, an input unit 1004, an output unit 1005, and an interface unit 1006. Each of these will be described below.

[0152] The control unit 1001 is a processor (for example, a CPU (Central Processing Unit), a GPU (Graphics Processing Unit), etc.) that executes various programs installed in the auxiliary storage unit 1003 .

[0153] The main memory unit 1002 includes a non-volatile memory (Read Only Memory (ROM)) and a volatile memory (Random Access Memory (RAM)). The ROM stores various programs, data, etc. required for the control unit 1001 to execute various programs installed in the auxiliary memory unit 1003. The RAM provides a working area into which the various programs installed in the auxiliary memory unit 1003 are expanded when executed by the control unit 1001.

[0154] The auxiliary storage unit 1003 is an auxiliary storage device that stores various programs and information used when the various programs are executed.

[0155] The input unit 1004 is an input device through which the operator of the estimation device 10 inputs various instructions to the estimation device 10 .

[0156] The output unit 1005 is an output device that outputs the internal state of the estimation device 10 and the like.

[0157] The interface unit 1006 is a communication device for connecting to a network and communicating with other devices.

[0158] The system 1 may be configured as follows: - When using the results of a health checkup, measurements from other measurement institutions or personal wearable devices, estimated values ​​from images captured by a camera on a mobile device, or self-reported values, the index value measurement device 20 is not required, and data may be sent to the estimation device via a network from an external measurement device, the user's mobile device, a mirror that can display information (such as a smart mirror), etc. - Customers are invited to a store or shop, and a skin diagnosis, recommendations, and solutions are provided. - After a diagnosis is conducted at a store or shop, the diagnosis results are transferred to the user's personal computer or mobile device, where the diagnosis results, recommendations, and solutions can be viewed.

[0159] In the second to fourth embodiments, the method of presenting the results of the skin diagnosis includes a method of presenting the future skin condition, momentum of skin change over time, recommendations, and solutions on a single screen, a method of presenting them sequentially on multiple screens, etc. - In the present invention, both the above-mentioned estimation of the future skin condition and the estimation of the momentum of skin change over time are performed, and each estimation result can be presented to the user and recommendations and solutions can be provided according to each estimation result.

[0160] Although the examples of the present invention have been described in detail above, the present invention is not limited to the specific embodiments described above, and various modifications and changes are possible within the scope of the gist of the present invention as set forth in the claims.

[0161] This international application claims priority based on Japanese Patent Application No. 2024-083707, filed on May 22, 2024, the entire contents of which are incorporated herein by reference.

[0162] REFERENCE SIGNS LIST 1 System 10 Estimation device 11 Terminal 20 Index value measurement device 30 Subject 101 Acquisition unit 102 Classification unit 103 Evaluation unit 104 Estimation unit 105 Proposal unit 1001 Control unit 1002 Main memory unit 1003 Auxiliary memory unit 1004 Input unit 1005 Output unit 1006 Interface unit

Claims

1. A method for evaluating the physical and mental effects of skin condition, comprising a step of classifying internal indicators, indicators of substances released from the body to the outside, and / or body language indicators based on changes due to external stimuli and the persistence of such changes.

2. The evaluation method according to claim 1, wherein the classification of the internal indicators and / or indicators of substances released from the body to the outside is determined by the degree or presence of change due to external stimuli and whether or not the change is persistent.

3. The evaluation method according to claim 1, wherein the indicators of the body and / or the indicators of substances released from the body to the outside are one or more of the following: a small change in response to external stimuli and the change is persistent; a large change in response to external stimuli and the change is not persistent; a large change in response to external stimuli and the change is persistent; or a small change in response to external stimuli and the change is not persistent.

4. The indicators that change little due to external stimuli and whose changes are persistent are height, weight, BMI, grip strength, bone density, muscle mass, lean body mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing; the indicators that change much due to external stimuli and whose changes are not persistent are brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio; The evaluation method according to claim 1, wherein the indicators that change significantly and sustainably due to external stimuli are immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone; the indicators that change only slightly and sustainably due to external stimuli are metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen; and the body language indicators are walking speed, walking posture, movement frequency, and facial distortion.

5. The evaluation method according to claim 1, wherein the internal indicators and / or indicators of substances released from the body to the outside are classified, and the physical and mental condition is evaluated based on the actual measured values ​​of indicators belonging to the same classification.

6. The evaluation method according to claim 5, wherein the level of the mind and body is one or more of the level of ability of the body and mind to have a positive effect on the skin, the level of ability of the body and mind to develop the skin in a positive direction, and the level of ability of the body and mind to produce good skin.

7. The evaluation method according to claim 1, further comprising the steps of classifying the indices within the body and / or the indices of substances released from the body to the outside, evaluating the degree of mental and physical condition based on the actual measured values ​​of indices belonging to the same classification, and comparing the degree between different classifications.

8. A method for proposing measures to improve future skin condition based on the evaluation method described in any one of claims 1 to 7.

9. A method for estimating future skin conditions, comprising a step of classifying indicators within the body and / or indicators of substances released from the body to the outside based on changes due to external stimuli and the persistence of those changes, and using one or more of the classifications.

10. The estimation method described in claim 9, wherein the classification of the internal indicators and / or indicators of substances released from the body to the outside is determined by the degree or presence of change due to external stimuli, and whether or not the change is persistent.

11. The estimation method described in claim 9, wherein the indicators within the body and / or indicators of substances released from the body to the outside are one or more of the following: indicators that change little in response to external stimuli but the change is persistent; indicators that change big in response to external stimuli but the change is not persistent; indicators that change big in response to external stimuli but the change is persistent; indicators that change little in response to external stimuli but the change is not persistent.

12. The indicators that change little due to external stimuli and whose changes are persistent are height, weight, BMI, grip strength, bone density, muscle mass, lean body mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing; the indicators that change much due to external stimuli and whose changes are not persistent are brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio; The method of claim 9, wherein the indicators that change significantly and sustainably due to external stimuli are immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone, and the indicators that change only slightly and sustainably due to external stimuli are metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen.

13. The estimation method according to claim 9, wherein the internal indicators and / or indicators of substances released from the body to the outside are classified, and the physical and mental condition is evaluated based on the actual measured values ​​of indicators belonging to the same classification.

14. The estimation method according to claim 13, wherein the physical and mental level is one or more of the level of ability to have a positive effect on the skin through the body and mind, the level of ability to develop the skin in a positive direction through the body and mind, and the level of ability to produce good skin through the body and mind.

15. The estimation method according to claim 9, further comprising a step of classifying the indices within the body and / or the indices of substances released from the body to the outside, evaluating the degree of mental and physical condition based on the actual measured values ​​of indices belonging to the same classification, and comparing the degree between different classifications.

16. A method for proposing measures to improve future skin condition based on the estimation method described in any one of claims 9 to 15.

17. An estimation method comprising a step of classifying indicators within the body and / or indicators of substances released from the body to the outside based on changes due to external stimuli and the persistence of those changes, and estimating the momentum of changes in the skin over time using one or more of the classifications.

18. The estimation method described in claim 17, wherein the classification of the internal indicators and / or indicators of substances released from the body to the outside is determined by the degree or presence of change due to external stimuli, and whether or not the change is persistent.

19. The estimation method described in claim 17, wherein the indicators of the body and / or indicators of substances released from the body to the outside are one or more of the following: indicators that change little in response to external stimuli but the change is persistent; indicators that change big in response to external stimuli but the change is not persistent; indicators that change big in response to external stimuli but the change is persistent; indicators that change little in response to external stimuli but the change is not persistent.

20. The indicators that change little due to external stimuli and whose changes are persistent are height, weight, BMI, grip strength, bone density, muscle mass, lean body mass, vascular density, blood pressure, advanced glycation end products, LDL cholesterol level, eGFR level, physical flexibility, walking speed, sleep characteristics, personality traits, movement frequency, and hearing; the indicators that change much due to external stimuli and whose changes are not persistent are brain waves, body temperature, heart rate, body water content, blood flow, autonomic nerves, intestinal environment, blood glycation level, sebaceous gland secretions, cerebral blood flow, potassium, sodium, walking speed, sense of smell, estrogen, testosterone, and estrogen / progesterone ratio; The method of claim 17, wherein the indicators that change significantly and sustainably due to external stimuli are immunity, inflammation, stratum corneum SCCA1, oxidation, brain waves, minerals, vitamins, psychological state (stress, motivation), fatigue, sleep state, ferritin, glycoalbumin, ALP, albumin, total protein, walking posture, facial distortion, taste, vision, and progesterone, and the indicators that change only slightly and sustainably due to external stimuli are metabolism / excretion, sweat rate, basal metabolic rate, active metabolic rate, amount of toxic substances in urine, urinary urea, urinary protein, and urea nitrogen.

21. The estimation method according to claim 17, wherein the internal indicators and / or indicators of substances released from the body to the outside are classified, and the physical and mental condition is evaluated based on the actual measured values ​​of indicators belonging to the same classification.

22. The estimation method according to claim 21, wherein the physical and mental level is one or more of the level of ability to have a positive effect on the skin through the body and mind, the level of ability to develop the skin in a positive direction through the body and mind, and the level of ability to produce good skin through the body and mind.

23. The estimation method according to claim 17, further comprising a step of classifying the indices within the body and / or the indices of substances released from the body to the outside, evaluating the degree of mental and physical condition based on the actual measured values ​​of indices belonging to the same classification, and comparing the degree between different classifications.

24. A method for proposing measures to improve future skin condition based on the estimation method described in any one of claims 17 to 23.

25. The estimation method according to claim 9, wherein the skin condition is one or more of moisture, complexion, transparency, and firmness.

26. The estimation method according to claim 17, wherein the skin condition is one or more of wrinkles, age spots, and sagging.

27. The estimation method according to claim 25, wherein when the skin condition is moist, the skin index is one or more of the following: moisture content, amount of water evaporation, substance permeability, number of textures, uniformity of texture, and size of keratinocytes.

28. The estimation method according to claim 25, wherein when the skin condition is a complexion, the skin index is one or more of the a* value, the area of ​​redness, unevenness of color (unevenness of redness), and intensity of redness.

29. The estimation method according to claim 25, wherein when the skin condition is transparency, the skin index is one or more of transparency, brightness, and L* value.

30. The estimation method according to claim 25, wherein when the skin condition is firmness, the skin index is one or more of elasticity, viscosity, softness, elongation rate, return rate after stretching, and return speed after stretching.

31. The estimation method according to claim 26, wherein when the skin condition is wrinkles, the skin index is one or more of the wrinkle area, the number of wrinkles, the maximum wrinkle depth, the variance of multiple wrinkle areas, and the change in skin surface shape.

32. The estimation method according to claim 26, wherein when the skin condition is blemishes, the skin index is one or more of the number of blemishes, the darkness of the blemishes, the area of ​​the blemishes, the maximum area of ​​the blemishes, and the maximum density of the blemishes.

33. The estimation method according to claim 26, wherein when the skin condition is sagging, the skin indicator is one or more of the following: changes in the chin circumference, nasolabial folds, size of eye bags, sagging eyelids, and marionette lines.

34. The estimation method according to claim 17, wherein the momentum of the skin change over time indicates whether or not there will be a change in skin condition over the next N years, the degree of change, and the direction of change.

35. A method for proposing measures to improve future skin condition based on the estimation method described in claim 34.

36. An estimation method for estimating the momentum of skin changes over time based on actual measurements of mental and physical indices.

37. The estimation method according to claim 36, which estimates whether or not there will be a change in skin condition over the next N years, the degree of change, and the direction of change.

38. The estimation method according to claim 36, wherein the skin condition is one or more of wrinkles, age spots, sagging, moisture, complexion, transparency, and firmness.

39. The estimation method according to claim 38, wherein when the skin condition is wrinkles, the skin index is one or more of the wrinkle area, the number of wrinkles, the maximum wrinkle depth, the variance of multiple wrinkle areas, and changes in the shape of the skin surface.

40. The estimation method according to claim 38, wherein when the skin condition is blemishes, the skin index is one or more of the number of blemishes, the darkness of the blemishes, the area of ​​the blemishes, the maximum area of ​​the blemishes, and the maximum density of the blemishes.

41. The estimation method according to claim 38, wherein when the skin condition is sagging, the skin indicator is one or more of the following: changes in the circumferential line around the chin, nasolabial folds, size of bags under the eyes, sagging eyelids, and marionette lines.

42. The estimation method described in claim 36, wherein the physical and mental indicators are one or more of SCCA1, HbA1C, LDL cholesterol, sebum amount, calcium amount, bone density, HDL cholesterol, blood CRP, total protein, intestinal environment, AGEs, and lifestyle habits.

43. A method for proposing measures to improve future skin condition based on the estimation method described in any one of claims 36 to 42.

44. The evaluation method according to claim 1, wherein the indicators within the body and / or the indicators of substances released from the body to the outside are related to skin condition.

45. The estimation method according to claim 9, wherein the indicators within the body and / or the indicators of substances released from the body to the outside are related to skin condition.

46. ​​The estimation method according to claim 17, wherein the indicators within the body and / or the indicators of substances released from the body to the outside are related to skin condition.

47. The estimation method according to claim 36, wherein the physical and mental indicators are indicators that affect the skin condition a certain period after measurement.

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