Bispecific antibody against human c-met and human EGFR, and use thereof

WO2025247296A1PCT designated stage Publication Date: 2025-12-04IMBIORAY (HANGZHOU) BIOMEDICINE CO LTD
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Patent Information

Application Number
PCT/CN2025/097888
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-05-30
Filing Date
2025-05-29
Publication Date
2025-12-04

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Abstract

Provided in the present application is a bispecific antibody, which contains a first antigen-binding fragment against a human mesenchymal-epithelial transition factor (c-Met) and a second antigen-binding fragment against a human epidermal growth factor receptor (EGFR). In addition, further provided in the present application is the medical and biological use of the bispecific antibody.
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Citation Information

Patent Citations

  • Bispecific EGFR / c-Met antibodies

    CN104955838A

  • Antibodies binded with EGFR and cMET

    CN111094351A

  • Stable formulations comprising bispecific EGFR / C-MET antibodies

    CN116194485A

  • High concentration bispecific antibody formulations

    CN117177740A