Floor-standing cryogenic storage refrigerator
By designing the roller shutter channel and sample retrieval mechanism of the vertical low-temperature storage refrigerator, sample storage and retrieval can be achieved without opening the entire compartment door, which solves the problem of the impact of temperature changes on biological samples and improves storage efficiency and sample viability.
Patent Information
- Application Number
- PCT/CN2025/070480
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-07-29
- Filing Date
- 2025-01-03
- Publication Date
- 2026-02-05
AI Technical Summary
Existing low-temperature storage refrigerators require frequent opening of the door during sample handling, leading to temperature fluctuations and affecting the viability of biological samples.
Design a vertical low-temperature storage refrigerator that uses a roller shutter channel assembly and a sample shovel mechanism. Samples are lifted and retrieved through a transfer window, avoiding the need to open the entire door. Combined with the gripping mechanism, the multi-functional area can be moved freely and kept warm.
This reduces the time samples are exposed to non-low-temperature environments, maintains sample viability, and improves storage efficiency and safety.
Smart Images

Figure CN2025070480_05022026_PF_FP_ABST
Abstract
Description
Vertical low-temperature storage refrigerator TECHNICAL FIELD
[0001] The present application relates to the technical field of sample storage, in particular to a vertical low-temperature storage refrigerator. BACKGROUND
[0002] In the field of biological sample storage, low-temperature access equipment is used for low-temperature storage of biological samples such as blood samples, vaccines, and virus seeds, so that the samples can be stored in a low-temperature state and remain active.
[0003] The low-temperature refrigerator used in the application number 20211110816 exposes the entire low-temperature area behind the door when accessing the sample, which is opened by a hinge, and then performs the taking and placing operation of the low-temperature storage object. Frequent temperature changes have an adverse effect on the preservation of objects in the low-temperature area, especially in the field of biological sample storage, biological samples are particularly sensitive to temperature changes and are easily inactivated. Therefore, the inventor designed a vertical low-temperature storage refrigerator. SUMMARY
[0004] This section aims to summarize some aspects of the embodiments of the present application and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the abstract and title of the specification to avoid obscuring the purpose of this section, abstract and title, and such simplifications or omissions cannot be used to limit the scope of the present application.
[0005] In view of the above or existing problems in the prior art, the present application is proposed.
[0006] Therefore, the purpose of the present application is to provide a vertical low-temperature storage refrigerator, which can access the sample without opening the entire cabin door, and only needs to lift the transfer window to the corresponding basket access port through the roller blind, so as to avoid exposing the samples in other baskets and improve the storage activity of the samples.
[0007] To solve the above technical problems, the present application provides the following technical scheme: a vertical low-temperature storage refrigerator, comprising a sample storage cabin and an operation cabin; the operation cabin is arranged on the side of the sample storage cabin, and the operation cabin can store, transport and pick up tubes in the sample storage cabin;
[0008] A roller blind passage assembly is arranged on the sample storage cabin and arranged in the operation cabin; a sample scooping mechanism is arranged in the operation cabin, the roller blind passage assembly and the sample scooping mechanism can be lifted, and the sample scooping mechanism can store and scoop the corresponding sample in the sample storage cabin through the roller blind passage assembly.
[0009] As a preferred scheme of the vertical low-temperature storage refrigerator, the roller shutter passage assembly comprises a roller shutter and a delivery window formed on the roller shutter; the roller shutter can drive the delivery window to rise and fall, and the sample scooping mechanism can access the sample storage cabin through the delivery window.
[0010] As a preferred scheme of the vertical low-temperature storage refrigerator, the roller shutter passage assembly further comprises a roller storage device arranged on the roller shutter, which can drive the roller shutter to rise and fall and can store the roller shutter.
[0011] As a preferred scheme of the vertical low-temperature storage refrigerator, the roller storage device comprises an upper roller shaft and a lower roller shaft; the upper roller shaft is arranged at the upper end of the roller shutter, and the lower roller shaft is arranged at the lower end of the roller shutter; the upper roller shaft can drive the roller shutter to rise and store, and the lower roller shaft can drive the roller shutter to fall and store.
[0012] As a preferred scheme of the vertical low-temperature storage refrigerator, the operation cabin is further provided with a grabbing mechanism, which can rotate and lift to grab the sample; the grabbing mechanism can be connected with the sample scooping mechanism.
[0013] As a preferred scheme of the vertical low-temperature storage refrigerator, the grabbing mechanism comprises a grabbing lifting assembly, a grabbing rotating assembly and a grabbing hand; the grabbing rotating assembly is arranged on the grabbing lifting assembly, and the grabbing hand is arranged on the grabbing rotating assembly; the grabbing lifting assembly can drive the grabbing rotating assembly to rise and fall, the grabbing rotating assembly can drive the grabbing hand to rotate, and the grabbing hand can grab the sample.
[0014] As a preferred scheme of the vertical low-temperature storage refrigerator, the side end of the grabbing mechanism is provided with a transfer tank storage area; the transfer tank storage area can place a transfer tank; the grabbing mechanism can grab the sample in the transfer tank.
[0015] As a preferred scheme of the vertical low-temperature storage refrigerator, the operation cabin is provided with a tank passage arranged on one side of the transfer tank storage area; the tank passage is provided with a tank operation door; the transfer tank enters the transfer tank storage area through the tank passage.
[0016] As a preferred scheme of the vertical low-temperature storage refrigerator, the side of the grabbing mechanism is further provided with a code scanning mechanism; the grabbing mechanism can grab the sample to the code scanning mechanism to scan the code.
[0017] As a preferred scheme of the vertical low-temperature storage refrigerator, the sample shoveling mechanism comprises a sample taking and placing lifting assembly, a taking and placing gripper assembly, and a turning support; the turning support is arranged on the sample taking and placing lifting assembly, the taking and placing gripper assembly is arranged on the turning support, the turning support can vertically slide on the sample taking and placing lifting assembly, the turning support turns around the sample taking and placing lifting assembly, and the taking and placing gripper assembly can take the sample and place it to a target position.
[0018] As a preferred scheme of the vertical low-temperature storage refrigerator, the taking and placing gripper assembly comprises a first telescopic part, a second limiting and clamping part, and a grabbing part; the second limiting and clamping part is arranged on the first telescopic part, the grabbing part is arranged on the second limiting and clamping part, the grabbing part can shovel the sample, the first telescopic part can drive the second limiting and clamping part and the grabbing part to move in a telescopic manner, the second limiting and clamping part can move in a telescopic manner on the first telescopic part, and the grabbing part can move in a telescopic manner on the second limiting and clamping part.
[0019] As a preferred scheme of the vertical low-temperature storage refrigerator, the second limiting and clamping part comprises a second driving part, a support frame, and a limiting strip; the second driving part can drive the support frame to move on the first telescopic part, the limiting strip is arranged on the inner side of the support frame, and the limiting strip can extrude the grabbing part.
[0020] As a preferred scheme of the vertical low-temperature storage refrigerator, the grabbing part comprises a pushing-out part, a shovel gripper, and an elastic part; the elastic part is arranged on the inner side of the shovel gripper, the pushing-out part is connected with the elastic part, the limiting strip can extrude and limit the elastic part on the shovel gripper, and the pushing-out part can push the elastic part and the shovel gripper away from the extrusion and limitation of the limiting strip.
[0021] As a preferred scheme of the vertical low-temperature storage refrigerator, a heat preservation isolation door is arranged in the operation cabin, and the heat preservation isolation door can open and close the roller shutter passage assembly.
[0022] As a preferred scheme of the vertical low-temperature storage refrigerator, a basket is arranged in the sample storage cabin, and the transfer window can be lifted to correspond to the storage groove on the basket.
[0023] As a preferred scheme of the vertical low-temperature storage refrigerator, an observation window and an operation end are arranged on the operation cabin; the observation window can observe the working state inside the operation cabin, and the operation end can issue an order and display the state inside the sample storage cabin.
[0024] The beneficial effects of the present application are as follows: the present application can drive the delivery window to ascend and descend through the rolling storage part, so as to match the corresponding storage groove on the basket in the sample storage cabin; the sample shoveling mechanism can be used to ascend and descend through the delivery window to shovel the sample on the basket, so as to avoid exposing other samples that do not need to be extracted, and reduce the adverse effects on the samples in the sample storage cabin; the grabbing mechanism, the transfer tank storage area and the code scanning mechanism are arranged together, so that the grabbing mechanism can be used to grab and transport the samples and scan the samples, and only one grabbing mechanism can realize the free movement of multiple functional areas; the rolling shutter channel assembly can be closed through the setting of the heat preservation isolation door, so as to further heat the sample storage cabin. BRIEF DESCRIPTION OF DRAWINGS
[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor. Among them:
[0026] Fig. 1 is a schematic diagram of the overall structure of the vertical low-temperature storage refrigerator.
[0027] Fig. 2 is a front view of the vertical low-temperature storage refrigerator.
[0028] Fig. 3 is a sectional view of the vertical low-temperature storage refrigerator at A-A in Fig. 2.
[0029] Fig. 4 is a schematic diagram of the sample shoveling mechanism of the vertical low-temperature storage refrigerator.
[0030] Fig. 5 is a schematic diagram of the rolling shutter channel assembly of the vertical low-temperature storage refrigerator.
[0031] Fig. 6 is a schematic diagram of the basket of the vertical low-temperature storage refrigerator.
[0032] Fig. 7 is an enlarged schematic diagram of the sample shoveling mechanism of the vertical low-temperature storage refrigerator.
[0033] Fig. 8 is an enlarged schematic diagram of the taking and placing gripper assembly of the vertical low-temperature storage refrigerator.
[0034] Fig. 9 is an exploded schematic diagram of the taking and placing gripper assembly of the vertical low-temperature storage refrigerator.
[0035] Fig. 10 is a schematic diagram of the grabbing mechanism of the vertical low-temperature storage refrigerator.
[0036] Figures: sample storage cabin, 1; operation cabin, 2; roller shutter passage assembly, 3; sample shoveling mechanism, 4; roller shutter; 31; transfer window, 32; roller housing, 33; upper roller shaft, 331; lower roller shaft, 332; grabbing mechanism, 5, grabbing lifting assembly, 51; grabbing rotating assembly, 52; grabber, 53; transfer tank, 991; tank body operation door, 992; code scanning mechanism, 6; sample taking and placing lifting assembly, 41; taking and placing grabber assembly, 42; turning support, 43; first telescopic piece, 421; second limiting clamping piece, 422; grabbing piece, 423; second driving piece, 4221; support frame, 4222; limiting strip, 4223; pushing-out piece, 4231; shovel grabber, 4232; tensioning piece, 4233; heat preservation isolation door, 7; basket, 8; observation window, 993; operation end, 994; DETAILED DESCRIPTION
[0037] In order to make the above objectives, features and advantages of the present application more obvious and easy to understand, the specific embodiments of the present application will be described in detail below with reference to the accompanying drawings.
[0038] In the following description, a large number of specific details are set forth in order to provide a thorough understanding of the present application, but the present application can also be implemented in other ways different from those described herein, and those skilled in the art can make similar generalizations without departing from the concept of the present application, so the present application is not limited to the specific embodiments disclosed below.
[0039] Secondly, the "one embodiment" or "embodiment" referred to herein means that the specific features, structures or characteristics can be included in at least one implementation of the present application. "In one embodiment" appearing in different places in the specification does not mean the same embodiment, nor is it an embodiment that is separate or alternative to other embodiments. Embodiment 1
[0040] Referring to FIGS. 1-4, the first embodiment of the present application provides a vertical low-temperature storage refrigerator, which includes a sample storage cabin 1 and an operation cabin 2. The sample storage cabin 1 is configured to store samples at low temperature, and the operation cabin 2 is configured to access, transfer and pick tubes of the samples in the sample storage cabin 1. The sample storage cabin 1 is provided with a roller shutter passage assembly 3, and a sample shoveling mechanism 4 is configured to shovel and transfer the samples in the sample storage cabin 1 through the roller shutter passage assembly 3.
[0041] Specifically, the sample storage cabin 1 and the operation cabin 2 are provided side by side, and the operation cabin 2 can access, transfer and pick tubes of the samples in the sample storage cabin 1.
[0042] The sample storage cabin 1 is provided with a roller shutter passage assembly 3, and the roller shutter passage assembly 3 is arranged in the operation cabin 2; the operation cabin 2 is provided with a sample shoveling mechanism 4, and the roller shutter passage assembly 3 and the sample shoveling mechanism 4 can be lifted, and the sample shoveling mechanism 4 can store and shovel the corresponding sample in the sample storage cabin 1 through the roller shutter passage assembly 3.
[0043] Preferably, the roller shutter passage assembly 3 can be lifted along with the sample shoveling mechanism 4, so that the sample shoveling mechanism 4 can smoothly pass through the roller shutter passage assembly 3 to store or shovel the sample.
[0044] In summary, the sample storage cabin 1 is provided with the roller shutter passage assembly 3 which can be lifted, and the target sample can be shoveled by the sample shoveling mechanism 4 which can be lifted, and other samples which do not need to be shoveled do not need to be exposed, so that the internal sample will not lose activity due to temperature change. Embodiment 2
[0045] Referring to FIGS. 1-10, the second embodiment of the present application is described. In the previous embodiment, the vertical low-temperature storage refrigerator includes a sample storage cabin 1 and an operation cabin 2. The sample storage cabin 1 can store the sample at low temperature, and the operation cabin 2 can access, transfer and pick the sample in the sample storage cabin 1. The roller shutter passage assembly 3 is arranged on the sample storage cabin 1, and the sample shoveling mechanism 4 passes through the roller shutter passage assembly 3 to shovel and transfer the sample in the sample storage cabin 1.
[0046] Specifically, the sample storage cabin 1 and the operation cabin 2 are provided. The operation cabin 2 is arranged on the side of the sample storage cabin 1, and can access, transfer and pick the sample in the sample storage cabin 1.
[0047] The sample storage cabin 1 is provided with a roller shutter passage assembly 3, and the roller shutter passage assembly 3 is arranged in the operation cabin 2; the operation cabin 2 is provided with a sample shoveling mechanism 4, and the roller shutter passage assembly 3 and the sample shoveling mechanism 4 can be lifted, and the sample shoveling mechanism 4 can store and shovel the corresponding sample in the sample storage cabin 1 through the roller shutter passage assembly 3.
[0048] Preferably, the roller shutter passage assembly 3 can be lifted along with the sample shoveling mechanism 4, so that the sample shoveling mechanism 4 can smoothly pass through the roller shutter passage assembly 3 to store or shovel the sample.
[0049] Further, the roller shutter passage assembly 3 includes a roller shutter 31 and a transmission window 32 arranged on the roller shutter 31. The roller shutter 31 can drive the transmission window 32 to be lifted, and the sample shoveling mechanism 4 can access the sample in the sample storage cabin 1 through the transmission window 32.
[0050] Further, the roller shutter passage assembly 3 further comprises a roller shutter storage device 33, which is arranged on the roller shutter 31 and can drive the roller shutter 31 to ascend and descend and can store the roller shutter 31.
[0051] Preferably, the roller shutter 31 can be lifted and stored by the roller shutter storage device 33, and the transmission window 32 can be lifted by the lifting movement of the roller shutter 31, the transmission window 32 can correspondingly match each layer of sample storage slots on the basket in the sample storage cabin 1, and the sample storage slots on each layer of the basket can be accessed or scooped by the sample scooping mechanism 4 through the transmission window 32.
[0052] Preferably, the roller shutter storage device 33 can drive the roller shutter 31 and the sample scooping mechanism 4 to ascend and descend together.
[0053] Preferably, the transmission window 32 can correspond to the sample storage slots on the corresponding basket, and other sample storage slots on the basket can be closed to reduce unnecessary temperature changes, and frequent access to samples will not adversely affect the samples in the basket.
[0054] Further, the roller shutter storage device 33 comprises an upper roller shaft 331 and a lower roller shaft 332, the upper roller shaft 331 is arranged at the upper end of the roller shutter 31, and the lower roller shaft 332 is arranged at the lower end of the roller shutter 31, the upper roller shaft 331 can drive the roller shutter 31 to ascend and store, and the lower roller shaft 332 can drive the roller shutter 31 to descend and store.
[0055] Further, the operation cabin 2 is further provided with a grabbing mechanism 5, which can rotate and lift to grab samples, and the grabbing mechanism 5 can be connected with the sample scooping mechanism 4.
[0056] Preferably, the sample scooping mechanism 4 can be lifted to the side of the grabbing mechanism 5 to cooperate with the grabbing mechanism 5.
[0057] Further, the grabbing mechanism 5 comprises a grabbing lifting assembly 51, a grabbing rotating assembly 52, and a grabbing hand 53, the grabbing rotating assembly 52 is arranged on the grabbing lifting assembly 51, the grabbing hand 53 is arranged on the grabbing rotating assembly 52, the grabbing lifting assembly 51 can drive the grabbing rotating assembly 52 to ascend and descend, the grabbing rotating assembly 52 can drive the grabbing hand 53 to rotate, and the grabbing hand 53 can grab samples.
[0058] Further, the grabbing mechanism 5 is provided with a transfer tank storage area at the side end, the transfer tank storage area can place a transfer tank 991, and the grabbing mechanism 5 can grab samples in the transfer tank 991.
[0059] Further, the operation cabin 2 is provided with a tank passage, which is arranged on one side of the transfer tank storage area, and the tank passage is provided with a tank operation door 992, and the transfer tank 991 enters the transfer tank storage area through the tank passage.
[0060] Preferably, the transfer tank 991 can be placed into the transfer tank storage area through the tank operation door 992, and the sample can be grabbed by the grabbing mechanism 5 or placed into the transfer tank 991.
[0061] Further, the grabbing mechanism 5 is further provided with a code scanning mechanism 6, and the grabbing mechanism 5 can rotate to the code scanning mechanism 6 to scan the code.
[0062] Preferably, the grabbing mechanism 5 is provided with the code scanning mechanism 6 and the transfer tank storage area on the side, and the sample shoveling mechanism 4 can be lifted and moved to the side of the grabbing mechanism 5; the grabbing mechanism 5 can freely move among the above three functional areas, and does not need to be additionally provided with the grabbing mechanism 5, thereby saving the cost.
[0063] Further, the sample shoveling mechanism 4 comprises a sample taking and placing lifting assembly 41, a taking and placing gripper assembly 42, and a turning support 43; the turning support 43 is arranged on the sample taking and placing lifting assembly 41, the taking and placing gripper assembly 42 is arranged on the turning support 43, the turning support 43 can vertically slide on the sample taking and placing lifting assembly 41, the turning support 43 can turn around the sample taking and placing lifting assembly 41, and the taking and placing gripper assembly 42 can grab the sample and store it in a target position.
[0064] Preferably, the turning support 43 is provided with at least one set, and the taking and placing gripper assembly 42 can stretch and grab the sample, and the taking and placing gripper assembly 42 can pass through the delivery window 32 to stretch and shovel the sample / biological plate rack in the sample storage cabin 1; or the sample / biological plate rack can be placed into the sample storage cabin 1.
[0065] Preferably, the sample taking and placing lifting assembly 41 can drive the turning support 43 and the taking and placing gripper assembly 42 to lift, and the turning support 43 can drive the taking and placing gripper assembly 42 to change the direction.
[0066] Further, the taking and placing gripper assembly 42 comprises a first stretching member 421, a second limiting and clamping member 422, and a grabbing member 423; the second limiting and clamping member 422 is arranged on the first stretching member 421, and the grabbing member 423 is arranged on the second limiting and clamping member 422; the grabbing member 423 can shovel the sample, the first stretching member 421 can drive the second limiting and clamping member 422 and the grabbing member 423 to stretch and move, the second limiting and clamping member 422 can stretch and move on the first stretching member 421, and the grabbing member 423 can stretch and move on the second limiting and clamping member 422.
[0067] Preferably, the first telescopic member 421 comprises a mounting base, a motor, a gear and a movable toothed plate; the motor and the gear are arranged on the mounting base, and the movable toothed plate is slidable on the mounting base; the motor drives the gear to rotate, and the gear drives the movable toothed plate to move forward and backward; the movable toothed plate is connected with the second limiting and clamping member 422, and the movable toothed plate drives the second limiting and clamping member 422 to move forward and backward when the movable toothed plate moves.
[0068] Preferably, through the movement of the first telescopic member 421 and the second limiting and clamping member 422, the sample or the sample board rack can be effectively scooped by the grabbing member 423.
[0069] Further, the second limiting and clamping member 422 comprises a second driving member 4221, a supporting frame 4222 and a limiting strip 4223; the second driving member 4221 can drive the supporting frame 4222 to move on the first telescopic member 421; the limiting strip 4223 is arranged on the inner side of the supporting frame 4222, and the limiting strip 4223 can extrude the grabbing member 423.
[0070] Preferably, the second driving member 4221 can be composed of a magnetic motor, a sliding rail and a sliding block; of course, the second driving member 4221 can also be a driving mechanism in the prior art, as long as it can drive.
[0071] Further, the grabbing member 423 comprises a pushing member 4231, a shovel plate gripper 4232 and an elastic member 4233; the inner side of the shovel plate gripper 4232 has the elastic member 4233, the pushing member 4231 is connected with the elastic member 4233, the limiting strip 4223 can extrude and limit the elastic member 4233 on the shovel plate gripper 4232, and the pushing member 4231 can push the elastic member 4233 and the shovel plate gripper 4232 to escape from the extrusion and limitation of the limiting strip 4223.
[0072] Preferably, the elastic member 4233 can be in the form of a spring, and the limiting strip 4223 in the supporting frame 4222 can extrude the shovel plate gripper 4232, so that the two groups of shovel plate grippers 4232 move towards the center, thereby pressing the board rack or the sample by the shovel plate grippers 4232.
[0073] Preferably, the pushing member 4231 is a center shaft motor, which can push the shovel plate gripper 4232 to escape from the limiting strip 4223 on the supporting frame 4222, so that the elastic member 4233 escapes from the extrusion of the limiting strip 4223, and the elastic member 4233 drives the two groups of shovel plate grippers 4232 to expand outward, thereby releasing the clamping limitation, and facilitating the board rack or the sample to be placed in a specific position.
[0074] Preferably, the shovel gripper 4232 can be pushed into the supporting frame 4222 by the pusher 4231, and the sample can be clamped by extruding the elastic member 4233 by the limiting strip 4223; of course, the shovel gripper 4232 can also be clamped by the supporting frame 4222 driven by the secondary driving member 4221, and the selection can be made according to the situation in the cabin.
[0075] Further, the operation cabin 2 is provided with a heat preservation isolation door 7, and the heat preservation isolation door 7 can open and close the roller shutter passage assembly 3.
[0076] Preferably, when the sample is not accessed, the roller shutter passage assembly 3 can be closed by the heat preservation isolation door 7, and the sample storage cabin 1 can be further heat preserved.
[0077] Further, the sample storage cabin 1 is provided with a basket 8, and the transfer window 32 can be lifted to correspond to the storage groove on the basket 8.
[0078] Preferably, the sample storage cabin 1 can be provided with a 360-degree rotatable basket 8.
[0079] Preferably, a plurality of groups of sample storage grooves are vertically arranged on the basket 8, and each storage groove can store a sample or a sample board rack.
[0080] Further, the operation cabin 2 is provided with an observation window 993 and an operation end 994; the observation window 993 can observe the internal working state of the operation cabin 2, and the operation end 994 can issue commands and display the internal state of the sample storage cabin 1.
[0081] In summary, the transfer window 32 can be lifted by the rolling storage member 33 to match the corresponding storage groove on the basket in the sample storage cabin 1, and the sample can be scooped by the sample scooping mechanism 4 lifting through the transfer window 32, so that other samples that do not need to be extracted are avoided from being exposed, and the adverse effect on the samples in the sample storage cabin 1 is reduced; the grabbing mechanism 5, the transfer tank storage area and the code scanning mechanism 6 are arranged together, and the sample scooping mechanism 4 can be lifted to the side of the grabbing mechanism 5, so that the grabbing mechanism 5 can be used to grab and transport the sample and scan, and only one grabbing mechanism 5 can realize the free movement of multiple functional areas; the roller shutter passage assembly 3 can be closed by the heat preservation isolation door 7, and the sample storage cabin 1 can be further heat preserved; the sample can be accessed by the sample scooping mechanism 4, and the sample can be prevented from falling off during the scooping and transferring process, and the sample or the board rack can be placed after being transferred to a specific position.
[0082] It is important to note that the construction and arrangement of the application shown in the various exemplary embodiments is illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review the present disclosure will readily appreciate that many modifications can be made to the embodiments without departing from the spirit and scope of the application, as described in the claims (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc. and the like). For example, the position of elements can be reversed or otherwise varied and the nature or number of elements can be altered or varied. Accordingly, all such modifications are intended to be included within the scope of the present application. The order or sequence of any process or method steps can be varied or re-sequenced without departing from the spirit of the application. Any "apparatus" or "device" described herein can be embodied in many different forms and a "means" for performing any function described herein can include any of the apparatus or structures described herein. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present application. Accordingly, the present application is not limited to the particular embodiments described in the specification.
[0083] In addition, for purposes of brevity of description, it is not the intention of the
[0084] It will be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions can be made. Such development efforts might be complex and time-consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art having the benefit of this disclosure.
[0085] It should be noted that the above-mentioned embodiments are only used to illustrate the technical solutions of the present application but not to limit the present application, and although the present application is described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or equivalent replaced without departing from the spirit and scope of the present application, and all should be included in the scope of the claims of the present application.
Claims
1. A vertical low-temperature storage refrigerator, characterized by: Including sample storage cabin (1), and operation cabin (2);The sample storage cabin (1) side is provided with operation cabin (2), the operation cabin (2) can be carried out sample storage cabin (1) will carry out sample access, transfer, pick tube; The sample storage cabin (1) is provided with rolling shutter passage component (3), and rolling shutter passage component (3) is arranged in operation cabin (2);Sample spade mechanism (4) is arranged in the operation cabin (2), and the rolling shutter passage component (3) and sample spade mechanism (4) can be lifted, and the sample spade mechanism (4) can be stored in the sample storage cabin (1) by rolling shutter passage component (3) to the corresponding sample of storage spade.
2. The upright cryogenic storage freezer of claim 1, wherein: The rolling shutter passage component (3) includes rolling shutter (31), and the transmission window (32) is opened in the rolling shutter (31);The rolling shutter (31) can drive the transmission window (32) to lift, and the sample spade mechanism (4) can access the sample storage cabin (1) through the transmission window (32).
3. The upright cryogenic storage freezer of claim 2, wherein: The rolling shutter passage component (3) further includes rolling storage (33), and the rolling storage (33) is arranged on the rolling shutter (31), and the rolling storage (33) can drive the rolling shutter (31) to lift and can store the rolling shutter (31).
4. The upright cryogenic storage freezer of claim 3, wherein: The rolling storage (33) includes upper winding shaft (331) and lower winding shaft (332);The upper winding shaft (331) is arranged at the upper end of the rolling shutter (31), and the lower winding shaft (332) is arranged at the lower end of the rolling shutter (31), and the upper winding shaft (331) can drive the rolling shutter (31) to rise and store, and the lower winding shaft (332) can drive the rolling shutter (31) to descend and store.
5. The upright cryogenic storage freezer of claim 1, wherein: The operation cabin (2) is further provided with a grabbing mechanism (5), and the grabbing mechanism (5) can rotate and lift to grab the sample, and the grabbing mechanism (5) can be connected with the sample spade mechanism (4).
6. The upright cryogenic storage freezer of claim 5, wherein: The grabbing mechanism (5) includes grabbing lifting assembly (51), grabbing rotating assembly (52) and gripper (53);The grabbing rotating assembly (52) is arranged on the grabbing lifting assembly (51), and the gripper (53) is arranged on the grabbing rotating assembly (52), the grabbing lifting assembly (51) can drive the grabbing rotating assembly (52) to lift, the grabbing rotating assembly (52) can drive the gripper (53) to rotate, and the gripper (53) can grab the sample.
7. The upright cryogenic storage freezer of claim 5, wherein: The side end of the grabbing mechanism (5) is provided with a transfer tank storage area, and the transfer tank (991) can be placed in the transfer tank storage area, and the grabbing mechanism (5) can grab the sample in the transfer tank (991).
8. The upright cryogenic storage freezer of claim 7, wherein: The operation cabin (2) is provided with a tank passage, and the tank passage is arranged on one side of the transfer tank storage area, and the tank passage is provided with a tank operation door (992), and the transfer tank (991) enters the transfer tank storage area through the tank passage.
9. The upright cryogenic storage freezer of claim 5, wherein: The side of the grabbing mechanism (5) is further provided with a code scanning mechanism (6), and the grabbing mechanism (5) can grab the sample and rotate to the code scanning mechanism (6) for code scanning.
10. The upright cryogenic storage freezer of claim 1, wherein: The sample shoveling mechanism (4) comprises a sample taking and placing lifting assembly (41), a taking and placing gripper assembly (42), and a steering support (43); the steering support (43) is arranged on the sample taking and placing lifting assembly (41), the taking and placing gripper assembly (42) is arranged on the steering support (43), the steering support (43) can vertically slide on the sample taking and placing lifting assembly (41), the steering support (43) can steer around the sample taking and placing lifting assembly (41), and the taking and placing gripper assembly (42) can take and store samples to a target position.
11. The upright cryogenic storage freezer of claim 10, wherein: The taking and placing gripper assembly (42) comprises a first telescopic member (421), a second limiting and clamping member (422), and a grabbing member (423); the second limiting and clamping member (422) is arranged on the first telescopic member (421), the grabbing member (423) is arranged on the second limiting and clamping member (422), the grabbing member (423) can shovel and take samples, the first telescopic member (421) can drive the second limiting and clamping member (422) and the grabbing member (423) to move telescopically, the second limiting and clamping member (422) can move telescopically on the first telescopic member (421), and the grabbing member (423) can move telescopically on the second limiting and clamping member (422).
12. The upright cryogenic storage freezer of claim 11, wherein: The second limiting and clamping member (422) comprises a second driving member (4221), a support frame (4222), and a limiting strip (4223); the second driving member (4221) can drive the support frame (4222) to move on the first telescopic member (421), the limiting strip (4223) is arranged on the inner side of the support frame (4222), and the limiting strip (4223) can extrude the grabbing member (423).
13. The upright cryogenic storage freezer of claim 12, wherein: The grabbing member (423) comprises a pushing member (4231), a shovel gripper (4232), and an elastic member (4233); the elastic member (4233) is arranged on the inner side of the shovel gripper (4232), the pushing member (4231) is connected with the elastic member (4233), the limiting strip (4223) can extrude and limit the elastic member (4233) on the shovel gripper (4232), and the pushing member (4231) can push the elastic member (4233) and the shovel gripper (4232) to be separated from the extrusion and limitation of the limiting strip (4223).
14. The upright cryogenic storage freezer of claim 1, wherein: The operation cabin (2) is provided with a heat preservation isolation door (7), and the heat preservation isolation door (7) can open and close the roller shutter channel assembly (3).
15. The upright cryogenic storage freezer of claim 2, wherein: The sample storage cabin (1) is provided with a basket (8), and the transfer window (32) can be lifted to correspond to the storage groove on the basket (8).
16. The upright cryogenic storage freezer of claim 1, wherein: The operation cabin (2) is provided with an observation window (993) and an operation end (994); the observation window (993) can observe the working state inside the operation cabin (2), and the operation end (994) can issue orders and display the internal state of the sample storage cabin (1).
Citation Information
Patent Citations
Polypeptides comprising immunoglobulin single variable domains targeting TNFα and il-23
WO2021110816A1