Mixtures for fungal control in corn
Fungicidal mixtures of Compound I or I-B with additional fungicides address resistance issues and enhance efficacy against corn pathogens, offering safer and more effective disease control.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- CORTEVA AGRISCIENCE LLC
- Filing Date
- 2025-11-04
- Publication Date
- 2026-05-15
AI Technical Summary
Current fungicides face challenges such as resistance development in pathogens, limited efficacy, and the need for safer, more effective formulations with reduced dosage and cost.
Development of fungicidal mixtures comprising Compound I or Compound I-B, combined with additional fungicides, including sterol biosynthesis inhibitors and other modes of action, to enhance efficacy against plant pathogens in corn.
The mixtures exhibit enhanced efficacy against fungal pathogens in corn, providing improved disease control with reduced toxicity to plants and lower application rates.
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Figure US2025053987_15052026_PF_FP_ABST
Abstract
Description
MIXTURES FOR FUNGAL CONTROL IN CORN1. CROSS REFERENCE TO RELATED APPLICATIONS
[0001] This application claims the benefit of U. S. Provisional Patent Application Serial No.63 / 718,603 filed November 9, 2024, and U. S. Provisional Patent Application Serial No.63 / 825,658 filed June 18, 2025, which are expressly incorporated by reference herein.2. FIELD OF THE INVENTION
[0002] Aspects of this disclosure relate to fungicidal mixtures and / or compositions containing (a) the Compound I and (b) at least one additional fungicide, including one or more commercial fungicides, to provide control of a plant fungal pathogen, and in particular effective against a pathogen in com.3. BACKGROUND
[0003] Fungicides are compounds of either natural or synthetic origin which act to treat or protect plants against damage caused by fungi and / or the ensuing disease. Currently the practice of agriculture relies on the use of fungicides. Using fungicides also allows a grower to increase the yield, quality of crop, and further increase the value of the crop.
[0004] However, no one fungicide is useful in all situations and repeated usage of a single fungicide frequently leads to the development of resistance of that particular pathogen and moreover, sometimes to other related fungicides. Research is being conducted to produce new fungicides, and to new combinations of fungicides that are safer, have better performance, require lower dosages, are easier to use, and cost less.4. SUMMARY
[0005] The present disclosure provides mixtures and / or compositions thereof comprising the compound of Formula 1:, i.e Compound I.
[0006] The present disclosure also provides mixtures and / or compositions thereof comprising the compound of Formula I-B:Compound I-B.
[0007] Further, this disclosure provides methods or processes that use Compound I or Compound I-B alone, but also provides using these compositions. The mixtures and / or compositions thereof are capable of preventing or curing, or both, disease in corn.
[0008] In some aspects, the mixtures disclosed herein exhibit enhanced efficacy. “Enhanced efficacy” in the present disclosure occurs when the activity of two or more compounds exceeds the sum of the activities of the compounds when used alone.
[0009] Surprisingly, these mixtures and / or compositions may have enhanced efficacy against pathogens in com. In accordance with this disclosure, mixtures and compositions are provided along with methods of their manufacture and methods for their use.
[0010] In one aspect, the present disclosure provides for a mixture of two compounds, wherein one of the compounds is the compound of Formula I. In one aspect, the present disclosure provides for a mixture of two compounds, wherein one of the compounds is the compound of Formula I-B. In one aspect, the present disclosure provides for a mixture of three compounds, wherein one of the compounds is the compound of Formula I. In one aspect, the present disclosure provides for a mixture of three compounds, wherein one of the compounds is the compound of Formula I-B.
[0011] In one aspect of this disclosure provided are mixtures including the compound of Formula 1 and at least one additional fungicide(s). In one aspect of this disclosure provided are mixtures including the compound of Formula I-B and at least one additional fungi cide(s).Additional fungicides include sterol biosynthesis inhibitors, respiration inhibitors, dihydroorotate dehydrogenase inhibitors, signal transduction inhibitors with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitors (FRAC Group P01), adenosine deaminase inhibitors, chemical multi-site inhibitors, methionine biosynthesisinhibitors, MAP / histidine kinase inhibitors, actin / myosin / fimbrin function inhibitors, tubulin dynamics modulators, fungicides with unknown mode of action, newly developed fungicides, and any combinations thereof.5. DETAILED DESCRIPTION5.1. Definitions
[0012] Various terms used in the specification and claims herein are defined as set forth below, unless otherwise specifically defined in this disclosure. All technical and scientific terms not defined herein have the meaning commonly understood by a person skilled in the art to which this disclosure belongs.
[0013] "Phytologically acceptable amount" refers to an amount of a compound that kills or inhibits the plant disease for which control is desired but is not significantly toxic to the plant. This amount will generally be from about 0.1 to about 1000 ppm (parts per million), with 1 to 500 ppm being preferred. The exact concentration of compound required varies with the fungal disease to be controlled, the type of formulation employed, the method of application, the particular plant species, climate conditions, and the like. A suitable application rate is typically in the range from about 0.10 to about 4 pounds / acre (about 0.01 to 0.45 grams per square meter, g / m2).
[0014] As used herein, the term "salt" refers to salts which are suitable for use in agriculture, i.e. they affect humans and lower animals without undue toxicity, irritation, allergic response and the like, and are commensurate with a reasonable benefit / risk ratio in agriculture. These salts are well known in the art. Salts of the compounds described herein include those derived from suitable inorganic and organic acids and bases. Examples of acid addition salts are salts of an amino group formed with inorganic acids such as hydrochloric acid, hydrobromic acid, phosphoric acid, sulfuric acid and perchloric acid or with organic acids such as acetic acid, oxalic acid, maleic acid, tartaric acid, citric acid, succinic acid or malonic acid or by using other methods used in the art such as ion exchange. Other salts include, but are not limited to, adipate, alginate, ascorbate, aspartate, benzenesulfonate, benzoate, bisulfate, borate, butyrate, camphorate, camphorsulfonate, citrate, cyclopentanepropionate, digluconate, dodecyl sulfate, ethanesulfonate, formate, fumarate, glucoheptonate, glycerophosphate, gluconate, hemisulfate,heptanoate, hexanoate, hydroiodide, 2-hydroxy-ethanesulfonate, lactobionate, lactate, laurate, lauryl sulfate, malate, maleate, malonate, methanesulfonate, 2-naphthalenesulfonate, nicotinate, nitrate, oleate, oxalate, palmitate, pamoate, pectinate, persulfate, 3 -phenylpropionate, phosphate, pivalate, propionate, stearate, succinate, sulfate, tartrate, thiocyanate, p-toluenesulfonate, undecanoate, valerate salts, and the like. Salts derived from appropriate bases include alkali metal, alkaline earth metal, and ammonium salts. Representative alkali or alkaline earth metal salts include sodium, lithium, potassium, calcium, magnesium, and the like. Further agriculturally acceptable salts include, when appropriate, nontoxic ammonium, quaternary ammonium, and amine cations formed using counterions such as halide, hydroxide, carboxylate, sulfate, phosphate, nitrate, lower alkyl sulfonate and aryl sulfonate.5.2. Additional interpretational conventions
[0015] The compounds described herein may exist as solvates, especially hydrates, and unless otherwise specified, all such solvates and hydrates are intended. Hydrates may form during manufacture of the compounds or compositions comprising the compounds, or hydrates may form over time due to the hygroscopic nature of the compounds. Compounds of the present technology may exist as organic solvates as well, including -dimethylformamide (DMF), ether, and alcohol solvates, among others. The identification and preparation of any particular solvate is within the skill of the ordinary artisan of synthetic organic or medicinal chemistry and are readily attainable using the textbook and other general synthetic references disclosed herein.
[0016] Throughout this application, the text refers to various aspects of the present compounds, compositions, and methods. The various aspects described are meant to provide a variety of illustrative examples and should not be construed as descriptions of alternative species. Rather, it should be noted that the descriptions of various aspects provided herein may be of overlapping scope. The aspects discussed herein are merely illustrative and are not meant to limit the scope of the present technology.
[0017] For the purposes of this specification and appended claims, unless otherwise indicated, all numbers expressing amounts, sizes, dimensions, proportions, shapes, formulations, parameters, percentages, parameters, quantities, characteristics, and other numerical values used in the specification and claims, are to be understood as being modified in all instances by theterm “about” even though the term “about” may not expressly appear with the value, amount or range. Accordingly, unless indicated to the contrary, the numerical parameters set forth in the following specification and attached claims are not and need not be exact, but may be approximate and / or larger or smaller as desired, reflecting tolerances, conversion factors, rounding off, measurement error and the like, and other factors known to those of skill in the art depending on the desired properties sought to be obtained by the presently disclosed subject matter. For example, the term “about,” when referring to a value can be meant to encompass variations of, in some aspects ± 100%, in some aspects ± 50%, in some aspects ± 20%, in some aspects ± 10%, in some aspects ± 5%, in some aspects ±1%, in some aspects ± 0.5%, and in some aspects ± 0.1% from the specified amount, as such variations are appropriate to perform the disclosed methods or employ the disclosed compositions.
[0018] As used herein and in the appended claims, singular articles such as “a,” “an” and “the” and similar referents in the context of describing the elements (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The use of the term “at least one” followed by a list of one or more items (for example, “at least one of A and B”) is to be construed to mean one item selected from the listed items (A or B) or any combination of two or more of the listed items (A and B), unless otherwise indicated herein or clearly contradicted by context. The terms “comprising,” “having,” “including,” and “containing” are to be construed as open-ended terms (i.e., meaning “including, but not limited to,”) unless otherwise noted.Recitation of ranges of values herein are merely intended to serve as a shorthand method of referring individually to each separate value falling within the range, including the upper and lower bounds of the range, unless otherwise indicated herein, and each separate value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g., “such as”) provided herein, is intended merely to better illuminate the aspects and does not pose a limitation on the scope of the claims unless otherwise stated. No language in the specification should be construed as indicating any non-claimed element as essential.5.3. Mixtures5.3.1. Components
[0019] The present disclosure provides mixtures and / or compositions thereof comprising the compound of Formula I:
[0020] The present disclosure also provides mixtures and / or compositions thereof comprising the compound of Formula I-B:
[0021] In one aspect, the compound of Formula I is 4-(difluoromethoxy)benzyl 4-(((ethyl(methyl)amino)methylene)amino)-2,5-dimethylbenzoate, or a salt, solvate, or hydrate thereof.
[0022] In one aspect, the compound of Formula I-B is 4-(difluoromethoxy)benzyl 4-(((ethyl(methyl)amino)methylene)amino)-2,5-dimethylbenzoate hydrochloride, or a solvate, or hydrate thereof.
[0023] Throughout the disclosure, reference to the compounds of Formula I and Formula I-B is read as also including all regioisomers, structural isomers, geometrical isomers, rotational isomers, tautomers, and stereoisomers, for example diastereomers, enantiomers, and mixtures thereof. In one aspect, the compound of Formula I-B is simply being specifically recited as the hydrochloride salt form of the compound of Formula I, and of course Formula I-B is covered under Formula I since it is defined above that all salts, solvates, or hydrates are within the scope of Formula I.
[0024] The compounds of Formula I and Formula I-B may also contain linkages (e.g., carbon-carbon bonds) wherein bond rotation is restricted about that particular linkage e.g., restriction resulting from the presence of a ring or a double bond. Accordingly, any cis / trans and E / Z isomers are expressly included in the present disclosure.
[0025] The compounds of Formula I and Formula I-B may also be present in multiple tautomeric forms. Where one or more tautomeric forms exist, the disclosure expressly includes all such tautomeric forms of the compounds described herein, even though only a single tautomeric form may be represented.
[0026] The compounds of Formula I and Formula I-B may exist in one or more crystalline or polymorphic forms. All crystalline forms and polymorphs of the compounds of the disclosure are expressly included in the present disclosure.
[0027] The structures of Formula I and Formula I-B, as well as their syntheses and fungicidal applications via agricultural formulation or composition, are disclosed in patent application No. PCT / US2024 / 027678, which is herein incorporated in its entirety. The compounds of Formula I and Formula I-B display some fungicidal activity in the reference above.
[0028] In one aspect, the mixtures disclosed herein exhibit enhanced efficacy.
[0029] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I:and at least one additional fungicide selected from the group consisting of fungicides with modes of action defined in the Fungicide Resistance Action Committee (FRAC)’s FRAC Classification of Fungicides poster (https: / / www.frac.info / docs / default-source / publications / frac-mode-of-action-poster / frac-moa-poster-2024.pdf), including nucleic acids metabolism, cytoskeleton and motor protein, respiration, amino acid and protein synthesis, signal transduction, lipid synthesis or transport / membrane integrity or function, melanin synthesis in cell wall, sterol biosynthesis in membranes, cell wall biosynthesis, host plant defense induction,chemicals with multi-site activity, unknown; and newly developed fungicides; and any combinations thereof. The fungicides with unknown mode of action are selected from the group consisting of cymoxanil, tecloftalam, triazoxide, flusulfamide, diclomezine, cyflufenamid, flutianil, ferimzone, tebufloquin, picarbutrazox, validamycin, and dodine. The newly developed fungicides are selected from the group consisting of aminotipyr, bifemetstrobin, cyclobunofen, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof.
[0030] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B:and at least one additional fungicide selected from the group consisting of: fungicides with modes of action defined in the Fungicide Resistance Action Committee (FRAC)’s FRAC Classification of Fungicides poster (https: / / www.frac.info / docs / default-source / publications / frac-mode-of-action-poster / frac-moa-poster-2024.pdf), including nucleic acids metabolism, cytoskeleton and motor protein, respiration, amino acid and protein synthesis, signal transduction, lipid synthesis or transport / membrane integrity or function, melanin synthesis in cell wall, sterol biosynthesis in membranes, cell wall biosynthesis, host plant defense induction, chemicals with multi-site activity, unknown, and newly developed fungicides, and any combinations thereof. The fungicides with unknown mode of action are selected from the group consisting of cymoxanil, tecloftalam, triazoxide, flusulfamide, diclomezine, cyflufenamid, flutianil, ferimzone, tebufloquin, picarbutrazox, validamycin, and dodine. The newly developed fungicides are selected from the group consisting of aminotipyr, bifemetstrobin, carmeconazolecyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound XI 0, and mixtures thereof.Additional Fungicides and Modes of action
[0031] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors of complex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), uncouplers of oxidative phosphorylation, signal transduction inhibitors with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitors (FRAC Group P01), actin / myosin / fimbrin function inhibitors, adenosine deaminase inhibitors, methionine biosynthesis inhibitors, MAP / histidine kinase inhibitors, dihydroorotate dehydrogenase inhibitors, tubulin dynamics modulators, chemical multi-site inhibitors, unknown mode of action fungicides, newly developed fungicides, and any combinations thereof.
[0032] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of: sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors of complex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), uncouplers of oxidative phosphorylation, signal transduction inhibitors with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitors (FRAC Group P01), actin / myosin / fimbrin function inhibitors, adenosine deaminase inhibitors, methionine biosynthesis inhibitors, MAP / histidine kinase inhibitors, dihydroorotate dehydrogenase inhibitors, tubulin dynamics modulators, chemical multi-site inhibitors, unknown mode of action fungicides, newly developed fungicides, and any combinations thereof.
[0033] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of: sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors of complex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), uncouplers of oxidative phosphorylation, signal transduction inhibitors with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitors (FRAC Group P01), actin / myosin / fimbrin function inhibitors, adenosine deaminase inhibitors, methionine biosynthesis inhibitors, MAP / histidine kinase inhibitors, dihydroorotate dehydrogenase inhibitors, tubulin dynamics modulators, chemical multi-site inhibitors, unknown mode of action fungicides, and any combinations thereof.
[0034] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of: sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors of complex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), uncouplers of oxidative phosphorylation, signal transduction inhibitors with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitors (FRAC Group P01), actin / myosin / fimbrin function inhibitors, adenosine deaminase inhibitors, methionine biosynthesis inhibitors, MAP / histidine kinase inhibitors, dihydroorotate dehydrogenase inhibitors, tubulin dynamics modulators, chemical multi-site inhibitors, unknown mode of action fungicides, and any combinations thereof.
[0035] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide with modes of action selected from the group consisting of: sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors of complex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), and any combinations thereof.
[0036] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide with modes of action selected from the group consisting of: sterol biosynthesis inhibitors (SBIs), succinate dehydrogenase inhibitors ofcomplex II (SDHIs), quinone outside inhibitors of complex III (MET III Qo), quinone inside inhibitors of complex III (MET III Qi), and any combinations thereof.
[0037] Aminotipyr is the common name for 4-[(5-methylthiazol-2-yl)oxy]benzyl 2-amino-6-methylpyridine-3 -carboxylate or 4-[(5-methylthiazol-2-yl)oxy]benzyl 2-amino-6-methylnicotinate.
[0038] Acibenzolar-S-methyl is the common name for S-methyl benzo[1,2,3]thiadiazole-7-carbothioate.
[0039] Azoxystrobin is the common name for methyl (2E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl} -3 -methoxy acrylate.
[0040] Benzovindiflupyr is the common name for N-[(1RS,4SR)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide.
[0041] Bixafen is the common name for N-(3',4'-dichloro-5-fluoro[1,1'-biphenyl]-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide.
[0042] Boscalid is the common name for 2-chloro-jV-(4'-chlorobiphenyl-2-yl)nicotinamide.
[0043] Bupirimate is the common name for 5-butyl-2-ethylamino-6-methylpyrimidin-4-yl dimethyl sulfamate.
[0044] Chlorothalonil is the common name for tetrachlorisophthalonitrile.
[0045] Fungicidal copper derivatives include, but are not limited to, copper hydroxide, copper oxides and copper salts. Preferred Fungicidal copper derivatives are copper oxides and copper salts. Copper salts belong to chemical multi-site inhibitors. Preferred copper salts include, but are not limited to, copper oxychloride. Copper oxychloride is the common name for dicopper chloride trihydroxide.
[0046] Cyclobunofen is the common name for the mixture of 80-100% A-[(15,25’)-2-(2,4-dibromophenyl)cyclobutyl]-2-nitrobenzamide and 20-0% of the (1?,2?)-enantiomer.
[0047] Cyflufenamid is the common name for (Z)-N-[α-(cyclopropylmethoxyimino)-2,3-difluoro-6-(trifluoromethyl)benzyl]-2-phenylacetamide.
[0048] Cyproconazole is the common name for (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol.
[0049] Cyprodinil is the common name for 4-cyclopropyl-6-methyl-7V-phenylpyrimidin-2-amine.
[0050] Difenoconazole is the common name for 3-chloro-4-[(2RS,4RS;2RS,4SR)-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether.
[0051] Epoxiconazole is the common name for rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole.
[0052] Famoxadone is the common name for (RS)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione.
[0053] Fenbuconazole is the common name for 4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butyronitrile.
[0054] Fenpicoxamid is the common name for (3S,6S,7R,8R)-8-benzyl-3-{3-[(isobutyryloxy)methoxy]-4-methoxypyridine-2-carboxamido}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl isobutyrate.
[0055] Fenpropidin is the common name for 1-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine.
[0056] Fenpropimorph is the common name for cis-4-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine.
[0057] Florylpicoxamid is the common name for (1S)-2,2-bis(4-fluorophenyl)-1-methylethyl N-[(3-acetoxy-4-methoxy-2-pyridyl)carbonyl]-L-alaninate.
[0058] Fluazinam is the common name for 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine.
[0059] Fludioxonil is the common name for 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile.
[0060] Fluindapyr is the common name for 3-(difluoromethyl)-N-[(3RS)-7-fluoro-2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl]-1-methylpyrazole-4-carboxamide.
[0061] Fluopyram is the common name for N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]ethyl}-α,α,α-trifluoro-o-toluamide.
[0062] Fluoxastrobin is the common name for (E)-{2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yloxy]phenyl}(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone O-methyloxime.
[0063] Fluoxytioconazole is the common name for 4-({6-[(2RS)-2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1H-1,2,4-triazol-1-yl)propyl]-3-pyridyl}oxy)benzonitrile.
[0064] Flutriafol is the common name for (RS)-2,4'-difluoro-α-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol.
[0065] Fluxapyroxad is the common name for 3-(difluoromethyl)-l-methyl-7V-(3’,4’,5’-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide.
[0066] Folpet is the common name for N-(trichloromethanesulfenyl)phthalimide, N-(trichloromethylthio)phthalimide.
[0067] Inpyrfluxam is the common name for 3-(difluoromethyl)-N-[(R)-2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl]-1-methylpyrazole-4-carboxamide.
[0068] Ipflufenoquin is the common name for 2-[2-(7,8-difluoro-2-methylquinolin-3-yloxy)-6-fluorophenyl]propan-2-ol.
[0069] Isofetamid is the common name for N-[1,1-dimethyl-2-(4-isopropoxy-o-tolyl)-2-oxoethyl]-3-methylthiophene-2-carboxamide.
[0070] Isoflucypram is the common name for N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methylpyrazole-4-carboxamide.
[0071] Mancozeb is the common name for manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt.
[0072] Mefentrifluconazole is the common name for 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol.
[0073] Metarylpicoxamid is the common name for (2S,3S)-3-(o-tolyl)butan-2-yl N-{[4-methoxy-3-(propanoyloxy)-2-pyridyl]carbonyl}-L-alaninate.
[0074] Metconazole is the common name for (1RS,5RS;1RS,5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol.
[0075] Metominostrobin is the common name for (E)-2-methoxyimino-N-methyl-2-(2-phenoxyphenyl)acetamide.
[0076] Metrafenone is the common name for 3'-bromo-2,3,4,6'-tetramethoxy-2',6-dimethylbenzophenone.
[0077] Metyltetraprole is the common name for 1-(2-{[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl}-3-methylphenyl)-1,4-dihydro-4-methyl-5H-tetrazol-5-one.
[0078] Myclobutanil is the common name for (RS)-2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile.
[0079] Penconazole is the common name for (RS)-1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole.
[0080] Penthiopyrad is the common name for (JR5’)-; V-[2-(l,3-dimethylbutyl)-3-thienyl]-l-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide.
[0081] Picoxystrobin is the common name for methyl (2E)-3-methoxy-2-[2-(6-(trifluoromethyl)-2-pyridyloxymethyl)phenyl]acrylate.
[0082] Propiconazole is the common name for (2RS,4RS;2RS,4SR)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole.
[0083] Proquinazid is the common name for 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one.
[0084] Prothioconazole is the common name for (RS)-2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-1,2,4-triazole-3-thione.
[0085] Pydiflumetofen is the common name for 3-(difluoromethyl)-JV-methoxy-l-methyl-JV-[(7?5’)-l-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide.
[0086] Pyraclostrobin is the common name for methyl N-{2-[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxymethylphenyl]-(N-methoxy)carbamate.
[0087] Pyrapropoyne is the common name for (Z)-N-{2-[3-chloro-5-(cyclopropylethynyl)-2-pyridyl]-2-(isopropoxyimino)ethyl}-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide.
[0088] Pyraziflumid is the common name for N-(3',4'-difluorobiphenyl-2-yl)-3-(trifluoromethyl)pyrazine-2-carboxamide.
[0089] Pyridachlometyl is the common name for 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5 -phenylpy ridazine.
[0090] Pyriofenone is the common name for (5-chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,6-trimethoxy-o-tolyl)methanone.
[0091] Quinaminoprole is the common name for N-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}ethyl)quinazolin-4-amine.
[0092] Quinofumelin is the common name for 3-(4,4-difluoro-3,4-dihydro-3,3-dimethylisoquinolin- 1 -yl)quinoline.
[0093] Quinoxyfen is the common name for 5,7-dichloro-4-quinolyl 4-fluorophenyl ether.
[0094] Spiroxamine is the common name for 8-tert-butyl-1,4-dioxaspiro[4.5]decan-2-ylmethyl(ethyl)(propyl)amine.
[0095] Sulfur is the common name for sulfur.
[0096] Fungicidal sulfur derivatives include, but are not limited to, sulfides, polysulfides, sulfate salts. Preferred fungicidal sulfur derivatives are polysulfides. Preferred polysulfides are inorganic polysulfides. Inorganic polysulfides belong to chemical multi-site inhibitors. Preferred inorganic poly sulfides include, but are not limited to, calcium polysulfide.
[0097] Tebuconazole is the common name for (S)-1-p-chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol.
[0098] Tetraconazole is the common name for (RS)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl 1,1,2,2-tetrafluoroethyl ether.
[0099] Trifloxystrobin is the common name for methyl (E)-methoxyimino-{(E)-α-[1-(α,α,α-trifluoro-m-tolyl)ethylideneaminooxy]-o-tolyl}acetate.
[0100] The fungicidal activity for the above-mentioned fungicides is described in The Online Pesticide Manual by the British Crop Production Council. Each one of these compounds can be obtained commercially through vendors such as Sigma Aldrich, TCI Chemical and the like, but if not, these compound can be synthesized according to the references mentioned herein which detail general synthetic procedures in organic chemistry to get to the final compound.
[0101] Bifemetstrobin is the common name for methyl (2Z)-3-methoxy-2-[(4-methylbiphenyl-3-yl)oxy]prop-2-enoate). The preparation and fungicidal activity of bifemetstrobin is described in patent publication No. WO 2021 / 153760A1 (incorporated by reference in its entirety for all purposes). The fungicidal activity of bifemetstrobin is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0102] Carmeconazole is the common name for methyl (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoate. The preparation and fungicidal activity of carmeconazole is described in patent publication No. WO 2019093522 Al (incorporated by reference in its entirety for all purposes). The fungicidal activity of carmeconazole is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0103] Cyclobunofen is the common name for the mixture of 80-100% N-[(1S,2S)-2-(2,4-dibromophenyl)cyclobutyl]-2-nitrobenzamide and 20–0% of the (1R,2R)-enantiomer. The preparation and fungicidal activity of cyclobunofen is described in patent publication No. WO 2025051203 Al (incorporated by reference in its entirety for all purposes). The fungicidal activity of cyclobunofen is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0104] Enprocymid is the common name for N-cyclopropyl-N-[2-(2,4-dichlorophenyl)allyl]-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide. The preparation and fungicidal activity of enprocymid is described in patent publication No. CN 113845480 A (incorporated by reference in its entirety for all purposes). The fungicidal activity of enprocymid is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0105] Feneptamidoquin is the common name for mixture of 80-100% N-[(1S)-1-benzyl-1,3-dimethylbutyl]-8-fluoroquinoline-3-carboxamide and 20–0% of the (1R)-isomer. The preparation and fungicidal activity of feneptamidoquin is described in patent publication No. WO 2017 / 153380A1 (incorporated by reference in its entirety for all purposes). The fungicidal activity of feneptamidoquin is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0106] Flufenoxadiazam is the common name for 2'-fluoro-4-[5-(trifluoromethyl)-l,2,4-oxadiazol-3-yl]benzanilide. The preparation and fungicidal activity of flufenoxadiazam is described in patent publication No. WO 2015 / 185485 Al (incorporated by reference in its entirety for all purposes). The fungicidal activity of flufenoxadiazam is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0107] Flumetyl sulforim is the common name for 5-fluoro-3,4-dihydro-4-imino-3-methyl-1-tosylpyrimidin-2(1H)-one, 5-fluoro-4-imino-3-methyl-1-[(4-methylphenyl)sulfonyl]-3,4-dihydropyrimidin-2(1H)-one. The preparation and fungicidal activity of flumetylsulforim is described in patent publication No. WO 2014 / 105845 Al (incorporated by reference in its entirety for all purposes). The fungicidal activity of flumetylsulforim is also described in The Online Pesticide Manual, by the British Crop Production Council.
[0108] The structure of Formula X-A and the preparation of compounds of Formula X-A is disclosed in patent publication No. WO 2017 / 055473 Al (incorporated by reference in its entirety for all purposes), wherein n, Al, A2, A3, A4, R5, R6, R7, and R8 of Formula X-A are defined. The compounds of Formula X-A display some fungicidal activity in the reference above.
[0109] The preferred compound of Formula X-A is the compound N-methoxy-N-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzyl)cyclopropanecarboxamide (XI), also known as cyprometoxazam. The preparation of Compound XI is disclosed in patent publication No. WO 2017 / 055473 Al. Compound XI displays some fungicidal activity in the reference above.
[0110] The structure of Formula X-B and the preparation of compounds of Formula X-B is disclosed in patent publication No. WO 2020 / 056090 Al (incorporated by reference in its entirety for all purposes), wherein E, L, J, A, and T are defined. The compounds of Formula X-B display some fungicidal activity in the reference above.X-B
[0111] The preferred compound of Formula X-B is the compound ethyl 1-(4-((2-(trifluoromethyl)-1,3-dioxolan-2-yl)methoxy)benzyl)-1H-pyrazole-4-carboxylate (X2). The preparation of Compound X2 is disclosed in patent publication No. WO 2020 / 056090 Al. Compound X2 displays some fungicidal activity in the reference above.X2
[0112] The structure of Formula X-C and the preparation of compounds of Formula X-C is disclosed in patent publication No. WO 2021 / 146522 Al (incorporated by reference in its entirety for all purposes), wherein Rl, R2, R3, R4a, R4b, R5, R5b, X, Z, W, L are defined. The compounds of Formula X-C display some fungicidal activity in the reference above.X-C
[0113] The preferred compound of Formula X-C is the compound 1-(4-cyclohexylphenyl)ethyl (4-formamido-3-hydroxypicolinoyl)-L-alaninate (X3). The preparation of Compound X3 is disclosed in patent publication No. WO 2021 / 146522 Al. Compound X3 displays some fungicidal activity in the reference above.
[0114] The structure of Formula X-D and the preparation of compounds of Formula X-D is disclosed in patent publication No. WO 2021 / 244952 Al (incorporated by reference in its entirety for all purposes), wherein A, Rl, R2, R3, R4, R5, R6, R7, and R8 are defined. The compounds of Formula X-D display some fungicidal activity in the reference above.
[0115] The preferred compounds of Formula X-D are the compounds 2-(N-(2,6-difluoropyridin-4-yl)tetrahydro-2H-pyran-4-carboxamido)-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide (X4a), 2-(N-(2,6-difluoropyridin-4-yl)oxetane-3-carboxamido)-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide (X4b), and 2-(N-(2,6-difluoropyridin-4-yl)tetrahydrofuran-2-carboxamido)-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide (X4c). The preparations of Compound X4a, X4b, and X4c are disclosed in patent publication No. WO 2021 / 244952 Al. Compounds X4a, X4b, and X4c display some fungicidal activity in the reference above.
[0116] The compound (E)-3-methyl-N-(1-(naphthalen-2-yl)ethylidene)benzohydrazide (X5) and its preparation is disclosed in patent publication No. WO 2016 / 123191 Al (incorporated by reference in its entirety for all purposes). Compound X5 displays some fungicidal activity in the reference above.
[0117] The structure of Formula X-F and the preparation of compounds of Formula X-F is disclosed in patent publication No. WO 2020 / 193387 Al (incorporated by reference in its entirety for all purposes), wherein Rl, R2, R3, and R4 are defined. The compounds of Formula X-F display some fungicidal activity in the reference above.
[0118] The preferred compound of Formula X-F is the compound methyl (Z)-2-(5-cyclohexyl-2-methylphenoxy)-3-methoxyacrylate (X6), also known as metcyclofenstrobin. The preparation of Compound X6 is disclosed in patent publication No. WO 2020 / 193387 Al. Compound X6 displays some fungicidal activity in the reference above.
[0119] The structure of Formula X-G and the preparation of compounds of Formula X-G is disclosed in patent publication No. WO 2020 / 127780 Al (incorporated by reference in its entirety for all purposes), wherein Rl, R2, R3, R4, R5, R6, R7, R8, Q, A, T, and L are defined. The compounds of Formula X-G display some fungicidal activity in the reference above.
[0120] The preferred compound of Formula X-G is the compound (S)-3-(3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl)-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4 / f- 1,2,4-oxadiazine (X7). The preparation of Compound X7 is disclosed in patent publication No. WO 2020 / 127780 Al. Compound X7 displays some fungicidal activity in the reference above.X7
[0121] The structure of Formula X-H and the preparation of compounds of Formula X-H is disclosed in patent publication No. WO 2020 / 208095 Al (incorporated by reference in its entirety for all purposes), wherein Rl, R2, R3, and R4 are defined. The compounds of Formula X-H display some fungicidal activity in the reference above.X-H
[0122] The preferred compound of Formula X-H is the compound (2S,3S)-3-(3,5-dichloropyridin-2-yl)butan-2-yl (3-((isobutyryloxy)methoxy)-4-methoxypicolinoyl)- / .-alaninate (X8). The preparation of Compound X8 is disclosed in patent publication No. WO 2020 / 208095 Al. Compound X8 displays some fungicidal activity in the reference above.
[0123] The structure of Formula X-J and the preparation of compounds of Formula X-J are disclosed in patent publication No. WO 2024 / 115546 Al (incorporated by reference in itsentirety for all purposes), where R1, R2, R3, R4, R5, R6, R8, R9, A1, A2, A3, B1, B2, and Z1are defined. The compounds of Formula X-J display some fungicidal activity in the reference above.X-J
[0124] The preferred compound of Formula X-J is the compound (5-(2,4-difluorophenyl)isoxazol-3-yl)(4-(1,5-dimethyl-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)methanone (X9). The preparation of Compound X9 is disclosed in patent publication No. WO 2024 / 115546 Al. Compound X9 displays some fungicidal activity in the reference above.
[0125] The structure of Formula X-K and the preparation of compounds of Formula X-K are disclosed in patent publication No. WO 2025 / 088176 Al (incorporated by reference in its entirety for all purposes), where R1and R5are defined. The compounds of Formula X-K display some fungicidal activity in the reference above.X-K
[0126] The preferred compound of Formula X-K is the compound ethyl (Z)-l-(4-((2-ethoxy-3,3,3-trifluoroprop-l-en-l-yl)oxy)benzyl)-1H-pyrazole-4-carboxylate (X10). The preparation of Compound X10 is disclosed in patent publication No. WO 2025 / 088176 A1. Compound X10 displays some fungicidal activity in the reference above.X10
[0127] Sterol biosynthesis inhibitors (SBIs) are a known class of fungicides in the art and include, but are not limited to, C14-demethylase inhibitors (DMI fungicides), for example prothioconazole, epoxiconazole, cyproconazole, myclobutanil, metconazole, difenoconazole, tebuconazole, tetraconazole, fenbuconazole, propiconazole, mefentrifluconazole, fluoxytioconazole, flutriafol, and penconazole, as well as Delta 14-reductase inhibitors, for example, fenpropidin, fenpropimorph and spiroxamine.
[0128] Preferred sterol biosynthesis inhibitors (SBIs) for use in com are cyproconazole, difenoconazole, flutriafol, epoxiconazole, fenbuconazole, fenpropimorph, mefentrifluconazole, metconazole, propiconazole, prothioconazole, tebuconazole, and tetraconazole. More preferred sterol biosynthesis inhibitors (SBIs) for use in corn are prothioconazole, cyproconazole, metconazole, difenoconazole, tebuconazole, tetraconazole, propiconazole, mefentrifluconazole, and flutriafol.
[0129] In one aspect, the disclosure provides for a mixture comprising a Compound I and one additional fungicide. In one aspect, the disclosure provides for a mixture comprising a Compound I and two additional fungicides. In one aspect, the disclosure provides for a mixture comprising a Compound I-B and one additional fungicide. In one aspect, the disclosure provides for a mixture comprising a Compound I-B and two additional fungicides.
[0130] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from sterol biosynthesis inhibitors (SBIs). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consistingof prothioconazole, epoxiconazole, cy proconazole, myclobutanil, metconazole, difenoconazole, tebuconazole, tetraconazole, fenbuconazole, propiconazole, mefentrifluconazole, fluoxytioconazole, flutriafol, penconazole, fenpropidin, fenpropimorph, spiroxamine, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of cy proconazole, difenoconazole, flutriafol, epoxiconazole, fenbuconazole, fenpropimorph, mefentrifluconazole, metconazole, propiconazole, prothioconazole, tebuconazole, tetraconazole, and mixtures thereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of prothioconazole, cyproconazole, metconazole, difenoconazole, tebuconazole, tetraconazole, propiconazole, mefentrifluconazole, flutriafol, and mixtures thereof.
[0131] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from sterol biosynthesis inhibitors (SBIs). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of prothioconazole, epoxiconazole, cyproconazole, myclobutanil, metconazole, difenoconazole, tebuconazole, tetraconazole, fenbuconazole, propiconazole, mefentrifluconazole, fluoxytioconazole, flutriafol, penconazole, fenpropidin, fenpropimorph, spiroxamine, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of cyproconazole, difenoconazole, flutriafol, epoxiconazole, fenbuconazole, fenpropimorph, mefentrifluconazole, metconazole, propiconazole, prothioconazole, tebuconazole, tetraconazole, and mixtures thereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of prothioconazole, cyproconazole, metconazole, difenoconazole, tebuconazole, tetraconazole, propiconazole, mefentrifluconazole, flutriafol, and mixtures thereof.
[0132] Uncouplers of oxidative phosphorylation are a known class of fungicides in the art and include, but are not limited to, dinitrophenyl crotonates, such as binapacryl, meptyldinocap, and dinocap, and 2,6-dinitroaniline compounds such as fluazinam.
[0133] Preferred uncoupler of oxidative phosphorylation for use in com is fluzainam.
[0134] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicides selected from uncouplers of oxidative phosphorylation. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and fluazinam.
[0135] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicides selected from uncouplers of oxidative phosphorylation. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and fluazinam.
[0136] Succinate dehydrogenase inhibitors of complex II (SDHIs) are a known class of fungicides in the art and include, but are not limited to, fluindapyr, fluxapyroxad, inpyrfluxam, benzovindiflupyr, isofetamid, isoflucypram, penthiopyrad, bixafen, pydiflumetofen, boscalid, pyrapropoyne, pyraziflumid, and fluopyram.
[0137] Preferred succinate dehydrogenase inhibitors of complex II (SDHIs) for use in corn are benzovindiflupyr, bixafen, fluindapyr, fluopyram, fluxapyroxad, inpyrfluxam, isofetamid, isoflucypram, penthiopyrad, and pydiflumetofen. More preferred succinate dehydrogenase inhibitors of complex II (SDHIs) for use in corn are benzovindiflupyr, bixafen, fluindapyr, fluopyram, fluxapyroxad, inpyrfluxam, isoflucypram, penthiopyrad, and pydiflumetofen.
[0138] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from succinate dehydrogenase inhibitors of complex II (SDHIs). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of fluindapyr, fluxapyroxad, inpyrfluxam, benzovindiflupyr, isofetamid, isoflucypram, penthiopyrad, bixafen, pydiflumetofen, boscalid, pyrapropoyne, pyraziflumid, fluopyram, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected fromthe group consisting of benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, inpyrfluxam, isofetamid, isoflucypram, pydiflumetofen, and mixtures thereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, inpyrfluxam, isofetamid, isoflucypram, pydiflumetofen, and mixtures thereof.
[0139] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from succinate dehydrogenase inhibitors of complex II (SDHIs). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of fluindapyr, fluxapyroxad, inpyrfluxam, benzovindiflupyr, isofetamid, isoflucypram, penthiopyrad, bixafen, pydiflumetofen, boscalid, pyrapropoyne, pyraziflumid, fluopyram, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, inpyrfluxam, isofetamid, isoflucypram, pydiflumetofen, and mixtures thereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of benzovindiflupyr, bixafen, fluindapyr, fluxapyroxad, inpyrfluxam, isofetamid, isoflucypram, pydiflumetofen, and mixtures thereof.
[0140] Quinone outside inhibitors of complex III (MET III Qo) are a known class of fungicides in the art and include, but are not limited to, pyraclostrobin, fluoxastrobin, azoxystrobin, trifloxystrobin, picoxystrobin, metominostrobin, metyltetraprole, and famoxadone.
[0141] Preferred quinone outside inhibitors of complex III (MET III Qo) for use in corn are azoxystrobin, fluoxastrobin, metyltetraprole, picoxystrobin, pyraclostrobin, and trifloxystrobin.
[0142] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from quinone outside inhibitors of complex III (MET III Qo). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from thegroup consisting of pyraclostrobin, fluoxastrobin, azoxystrobin, trifloxystrobin, picoxystrobin, metominostrobin, metyltetraprole, famoxadone, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of azoxystrobin, fluoxastrobin, metyltetraprole, picoxystrobin, pyraclostrobin, trifloxystrobin, and mixtures thereof.
[0143] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from quinone outside inhibitors of complex III (MET III Qo). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of pyraclostrobin, fluoxastrobin, azoxystrobin, trifloxystrobin, picoxystrobin, metominostrobin, metyltetraprole, famoxadone, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of azoxystrobin, fluoxastrobin, metyltetraprole, picoxystrobin, pyraclostrobin, trifloxystrobin, and mixtures thereof.
[0144] Chemical multi-site inhibitors are a known class of fungicides in the art and include, but are not limited to, thio- and dithiocarbamates, such as mancozeb; organochlorine compounds, such as chlorothalonil; phthalimides such as folpet; and inorganics such as copper oxychloride, sulfur, and inorganic polysulfides such as calcium polysulfide.
[0145] Preferred chemical multi-site inhibitors for use in corn are chlorothalonil, folpet, copper oxychloride, and mancozeb. More preferred chemical multi-site inhibitor for use in corn is folpet.
[0146] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from chemical multi-site inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of thio- and dithiocarbamates, organochlorine compounds, phthalimides, copper oxychloride, calcium polysulfide, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of chlorothalonil, folpet, copper oxychloride, mancozeb, and mixturesthereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and folpet.
[0147] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from chemical multi-site inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of thio- and dithiocarbamates, organochlorine compounds, phthalimides, copper oxychloride, calcium polysulfide, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of chlorothalonil, folpet, copper oxychloride, mancozeb, and mixtures thereof. In one particularly preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and folpet.
[0148] Quinone inside inhibitors of complex III (MET III Qi) are a known class of fungicides in the art and include, but are not limited to, fenpicoxamid, florylpicoxamid, and metarylpicoxamid.
[0149] Preferred quinone inside inhibitors of complex III (MET III Qi) for use in corn are fenpicoxamid and florylpicoxamid.
[0150] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from quinone inside inhibitor of complex III (MET III Qi). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of fenpicoxamid, florylpicoxamid, and metarylpicoxamid. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of fenpicoxamid, florylpicoxamid, and mixtures thereof.
[0151] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from quinone inside inhibitor of complex III (MET III Qi). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from thegroup consisting of fenpicoxamid, florylpicoxamid, and metarylpicoxamid. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of fenpicoxamid, florylpicoxamid, and mixtures thereof.
[0152] Signal transduction inhibitors with unknown mechanism (FRAC Group El) are a known class of fungicides in the art and include, but are not limited to, proquinazid and quinoxyfen.
[0153] Preferred Signal transduction inhibitor with unknown mechanism (FRAC Group El) for use in corn is proquinazid.
[0154] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from signal transduction inhibitors with unknown mechanism (FRAC Group El). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of proquinazid, quinoxyfen, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and proquinazid.
[0155] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from signal transduction inhibitors with unknown mechanism (FRAC Group El). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of proquinazid, quinoxyfen, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and proquinazid.
[0156] Host plant defense induction salicylate related inhibitors (FRAC Group P01) are a known class of fungicides in the art and include acibenzolar-S-methyl.
[0157] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from host plant defense induction salicylate related inhibitors (FRAC Group P01). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and acibenzolar-S-methyl.
[0158] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from host plant defense induction salicylate related inhibitors (FRAC Group P01). In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and acibenzolar-S-methyl.
[0159] Actin / myosin / fimbrin function inhibitors are a known class of fungicides in the art and include, but are not limited to, metrafenone and pyriofenone.
[0160] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from actin / myosin / fimbrin function inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of metrafenone, pyriofenone, and mixtures thereof.
[0161] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from actin / myosin / fimbrin function inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of metrafenone, pyriofenone, and mixtures thereof.
[0162] Adenosine deaminase inhibitors are a known class of fungicides in the art and include, but are not limited to, bupirimate.
[0163] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from adenosine deaminase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and bupirimate.
[0164] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from adenosine deaminase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and bupirimate.
[0165] Methionine biosynthesis inhibitors are a known class of fungicides in the art and include, but are not limited to, cyprodinil.
[0166] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from methionine biosynthesis inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and cyprodinil.
[0167] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from methionine biosynthesis inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and cyprodinil.
[0168] MAP / histidine kinase inhibitors are a known class of fungicides in the art and include, but are not limited to, fludioxonil.
[0169] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from MAP / histidine kinase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and fludioxonil.
[0170] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from MAP / histidine kinase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and fludioxonil.
[0171] Dihydroorotate dehydrogenase inhibitors are a known class of fungicides in the art and include, but are not limited to, feneptamidoquin, ipflufenoquin and quinofumelin.
[0172] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from dihydroorotate dehydrogenase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of feneptamidoquin, ipflufenoquin, quinofumelin, and mixtures thereof.
[0173] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from dihydroorotate dehydrogenase inhibitors. In one more preferred aspect, the disclosure provides for a mixture comprising acompound of Formula I-B and at least one additional fungicide selected from the group consisting of feneptamidoquin, ipflufenoquin, quinofumelin, and mixtures thereof.
[0174] Tubulin dynamics modulators are a known class of fungicides in the art and include pyridachlometyl.
[0175] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from tubulin dynamics modulators. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and pyridachlometyl.
[0176] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from tubulin dynamics modulators. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and pyridachlometyl.
[0177] Unknown mode of action fungicides are a known class in the art and include, but are not limited to, cyflufenamid.
[0178] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from unknown mode of action fungicides. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and cyflufenamid.
[0179] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from unknown mode of action fungicides. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and cyflufenamid.
[0180] Newly developed fungicides include, but are not limited to, aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, and Compound X10. Preferred newly developed fungicides are aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, and Compound XI 0.
[0181] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from the group consisting of feneptamidoquin, flufenoxadizam, flumetylsulforim, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and flufenoxadizam.
[0182] In one preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of FormulaX-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I and at least one additional fungicide selected from aminotipyr, bifemetstrobin, carmeconazole, cyclobunofen, enprocymid, feneptamidoquin, flufenoxadiazam, flumetylsulforim, quinaminoprole, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound XI 0, and mixtures thereof. In one more preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and at least one additional fungicide selected from the group consisting of feneptamidoquin, flufenoxadizam, flumetylsulforim, and mixtures thereof. In one most preferred aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and flufenoxadizam.
[0183] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and one additional fungicide. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and one additional fungicide. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and two additional fungicides. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and two additional fungicides.
[0184] “Enhanced efficacy” in the present disclosure refers to the simultaneous activity of two or more compounds resulting in a higher collective activity than the sum of the activities of the individual compounds.
[0185] In another aspect, the at least one additional fungicide may include 2-(thiocyanatomethylthio)-benzothiazole, 2-phenylphenol, 8-hydroxyquinoline sulfate, acibenzolar-S-methyl, ametoctradin, aminopyrifen, aminotipyr, amisulbrom, antimycin, azaconazole, azoxystrobin, benalaxyl, benomyl, benthiavalicarb-isopropyl, benzovindiflupyr, benzylaminobenzene-sulfonate (BABS) salt, bicarbonates, bifemetstrobin, biphenyl, bismerthiazol, bitertanol, bixafen, blasticidin-S, borax, Bordeaux mixture, boscalid,bromuconazole, bupirimate, calcium polysulfide, captafol, captan, carbendazim, carboxin, carpropamid, carvone, chlazafenone, chloroinconazide, chloroneb, chlorothalonil, chlozolinate, copper hydroxide, copper octanoate, copper oxychloride, copper sulfate, copper sulfate (tribasic), cuprous oxide, cyazofamid, carmeconazole, cyclobunofen, enprocymid, cyclobutrifluram, cyflufenamid, cymoxanil, cy proconazole, cyprodinil, dazomet, debacarb, diammonium ethylenebis-(dithiocarbamate), dichlofluanid, dichlorophen, diclocymet, diclomezine, dichloran, diethofencarb, difenoconazole, difenzoquat ion, diflumetorim, dimethomorph, dimoxystrobin, diniconazole, diniconazole-M, dinobuton, dinocap, diphenylamine, dithianon, dodemorph, dodemorph acetate, dodine, dodine free base, edifenphos, enestrobin, enestroburin,epoxiconazole, ethaboxam, ethoxyquin, etridiazole, famoxadone, fenamidone, fenarimol, fenbuconazole, feneptamidoquin, fenfuram, fenhexamid, fenopyramid, fenopyramid, fenoxanil, fenpiclonil, fenpropidin, fenpropimorph, fenpyrazamine, fentin, fentin acetate, fentin hydroxide, ferbam, ferimzone, fluazinam, flubeneteram, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, flumorph, fluopicolide, fluopyram, fluoroimide, fluoxapiprolin, fluoxastrobin, fluoxytioconazole, fluquinconazole, flusilazole, flusulfamide, flutianil, flutolanil, flutriafol, fluxapyroxad, folpet, formaldehyde, fosetyl, fosetyl-aluminium, fuberidazole, furalaxyl, furametpyr, gal quin, guazatine, guazatine acetates, GY-81, hexachlorobenzene, hexaconazole, hymexazol, imazalil, imazalil sulfate, imibenconazole, iminoctadine, iminoctadine triacetate, iminoctadine tris(albesilate), inpyrfluxam, iodocarb, ipconazole, ipfenpyrazolone, iprobenfos, iprodione, iprovalicarb, isofetamid, isoflucypram, isoprothiolane, isopyrazam, isotianil, kasugamycin, kasugamycin hydrochloride hydrate, kresoxium-methyl, laminarin, mancopper, mancozeb, mandipropamid, maneb, mefenoxam, mepanipyrim, mepronil, meptyl-dinocap, mercuric chloride, mercuric oxide, mercurous chloride, metalaxyl, metalaxyl-M, metam, metam-ammonium, metam-potassium, metam-sodium, metarylpicoxamid, metconazole, methasulfocarb, methyl iodide, methyl isothiocyanate, metiram, metominostrobin, metrafenone, mildiomycin, myclobutanil, nabam, nitrothal-isopropyl, nuarimol, octhilinone, ofurace, oleic acid (fatty acids), orysastrobin, oxadixyl, oxathiapiprolin, oxine-copper, oxpoconazole fumarate, oxycarboxin, pefurazoate, penconazole, pencycuron, penflufen, pentachlorophenol, pentachlorophenyl laurate, penthiopyrad, phenylmercury acetate, phosphonic acid, phthalide, picarbutrazox, picoxystrobin,polyoxin B, polyoxins, polyoxorim, potassium bicarbonate, potassium hydroxyquinoline sulfate, probenazole, prochloraz, procymidone, propamocarb, propamocarb hydrochloride, propiconazole, propineb, proquinazid, prothioconazole, pydiflumetofen, pyrametostrobin, pyraoxystrobin, pyraclostrobin, pyraziflumid, pyrazophos, pyribencarb, pyributicarb, pyrifenox, pyrimethanil, pyriofenone, pyrisoxazole, pyroquilon, quinoclamine, quinoxyfen, quintozene, seboctylamine, sedaxane, silthiofam, simeconazole, sodium 2-phenylphenoxide, sodium bicarbonate, sodium pentachlorophenoxide, spiroxamine, sulfur, fungicidal sulfur derivatives, SYP-Z048, tar oils, tebuconazole, tebufloquin, tecnazene, tetraconazole, thiabendazole, thifluzamide, thiophanate-methyl, thiram, tiadinil, tolclofos-methyl, tolprocarb, tolylfluanid, triadimefon, triadimenol, triazoxide, tricyclazole, tridemorph, trifloxystrobin, triflumizole, triforine, triticonazole, validamycin, valifenalate, valiphenal, vinclozolin, zineb, ziram, zoxamide, (S)-N-(3,5-dichlorophenyl)-2-(methoxymethyl)-succinimide, 1,2-di chloropropane, l,3-dichloro-l,l,3,3-tetrafluoroacetone hydrate, l-chloro-2,4-dinitronaphthalene, l-chloro-2-nitropropane, 2-(2-heptadecyl-2-imidazolin-l-yl)ethanol, 2,3-dihydro-5-phenyl-l,4-dithi-ine 1,1,4,4-tetraoxide, 2-methoxy ethylmercury acetate, 2-methoxy ethylmercury chloride, 2-methoxyethylmercury silicate, 3-(4-chlorophenyl)-5-methylrhodanine, 4-(2-nitroprop-l-enyl)phenyl thiocyanateme, ampropylfos, anilazine, azithiram, barium polysulfide, Bayer 32394, benodanil, benquinox, bentaluron, benzamacril; benzamacril-isobutyl, benzamorf, binapacryl, bi s(m ethylmercury) sulfate, bis(tributyltin) oxide, buthiobate, cadmium calcium copper zinc chromate sulfate, carbamorph, CECA, chlobenthiazone, chloraniformethan, chlorfenazole, chlorquinox, climbazole, copper bis(3-phenylsalicylate), copper zinc chromate, coumoxystrobin, cufraneb, cupric hydrazinium sulfate, cuprobam, cyclafuramid, cypendazole, cyprofuram, decafentin, dichlobentiazox, dichlone, dichlozoline, diclobutrazol, dimethirimol, dinocton, dinosulfon, dinoterbon, dipymetitrone, dipyrithione, ditalimfos, dodicin, drazoxolon, EBP, enoxastrobin, ESBP, etaconazole, etem, ethirim, fenaminstrobin, fenaminosulf, fenapanil, fenitropan, fenpicoxamid, florylpicoxamid, flufenoxystrobin, fluopimomide, fluotrimazole, furcarbanil, furconazole, furconazole-cis, furmecyclox, furophanate, glyodine, griseofulvin, halacrinate, Hercules 3944, hexylthiofos, ICIA0858, ipfentrifluconazole, ipflufenoquin, isopamphos, isovaledione, mandestrobin, mebenil, mecarbinzid, mefentrifluconazole,metazoxolon, methfuroxam, methylmercury dicyandiamide, metsulfovax, metyltetraprole, milneb, mucochloric anhydride, myclozolin, A-3,5-dichlorophenyl-succinimide, N-3-nitrophenylitaconimide, natamycin, N-ethylmercurio-4-toluenesulfonanilide, nickel bis(dimethyldithiocarbamate), OCH, phenylmercury dimethyldithiocarbamate, phenylmercury nitrate, phosdiphen, prothiocarb; prothiocarb hydrochloride, pyracarbolid, pyrapropoyne, pyridachlometyl, pyridinitril, pyrisoxazole, pyroxychlor, pyroxyfur, quinacetol; quinacetol sulfate, quinaminoprole, quinazamid, quinconazole, quinofumelin, rabenzazole, salicylanilide, SSF-109, sultropen, tecoram, thiadifluor, thicyofen, thiochlorfenphim, thiophanate, thioquinox, tioxymid, triamiphos, triarimol, triazbutil, trichlamide, triclopyricarb, triflumezopyrim, urbacid, zarilamid, compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound X1 (also known as cyprometoxazam), Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6 (also known as metcyclofenstrobin), Compound X7, Compound X8, Compound X9, Compound X10, and any combinations thereof
[0186] In another aspect, the additional fungicides may include 2-(thiocyanatomethylthio)-benzothiazole, 2-phenylphenol, 8-hydroxyquinoline sulfate, acibenzolar-S-methyl, ametoctradin, aminopyrifen, aminotipyr, amisulbrom, antimycin, azaconazole, azoxystrobin, benalaxyl, benomyl, benthiavalicarb-isopropyl, benzovindiflupyr, benzylaminobenzene-sulfonate (BABS) salt, bicarbonates, bifemetstrobin, biphenyl, bismerthiazol, bitertanol, bixafen, blasticidin-S, borax, Bordeaux mixture, boscalid, bromuconazole, bupirimate, calcium polysulfide, captafol, captan, carbendazim, carboxin, carpropamid, carvone, chlazafenone, chloroinconazide, chloroneb, chlorothalonil, chlozolinate, copper hydroxide, copper octanoate, copper oxychloride, copper sulfate, copper sulfate (tribasic), cuprous oxide, cyazofamid, carmeconazole, cyclobunofen, enprocymid, cyclobutrifluram, cyflufenamid, cymoxanil, cyproconazole, cyprodinil, dazomet, debacarb, diammonium ethylenebis-(dithiocarbamate), dichlofluanid, dichlorophen, diclocymet, diclomezine, dichloran, diethofencarb, difenoconazole, difenzoquat ion, diflumetorim, dimethomorph, dimoxystrobin, diniconazole, diniconazole-M, dinobuton,dinocap, diphenylamine, dithianon, dodemorph, dodemorph acetate, dodine, dodine free base, edifenphos, enestrobin, enestroburin, epoxiconazole, ethaboxam, ethoxyquin, etridiazole, famoxadone, fenamidone, fenarimol, fenbuconazole, feneptamidoquin, fenfuram, fenhexamid, fenopyramid, fenoxanil, fenpiclonil, fenpropidin, fenpropimorph, fenpyrazamine, fentin, fentin acetate, fentin hydroxide, ferbam, ferimzone, fluazinam, flubeneteram, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, flumorph, fluopicolide, fluopyram, fluoroimide, fluoxapiprolin, fluoxastrobin, fluoxytioconazole, fluquinconazole, flusilazole, flusulfamide, flutianil, flutolanil, flutriafol, fluxapyroxad, folpet, formaldehyde, fosetyl, fosetyl-aluminium, fuberidazole, furalaxyl, furametpyr, gal quin, guazatine, guazatine acetates, GY-81, hexachlorobenzene, hexaconazole, hymexazol, imazalil, imazalil sulfate, imibenconazole, iminoctadine, iminoctadine triacetate, iminoctadine tris(albesilate), inpyrfluxam, iodocarb, ipconazole, ipfenpyrazolone, iprobenfos, iprodione, iprovalicarb, isofetamid, isoflucypram, isoprothiolane, isopyrazam, isotianil, kasugamycin, kasugamycin hydrochloride hydrate, kresoxium-methyl, laminarin, mancopper, mancozeb, mandipropamid, maneb, mefenoxam, mepanipyrim, mepronil, meptyl-dinocap, mercuric chloride, mercuric oxide, mercurous chloride, metalaxyl, metalaxyl-M, metam, metam-ammonium, metam-potassium, metam-sodium, metarylpicoxamid, metconazole, methasulfocarb, methyl iodide, methyl isothiocyanate, metiram, metominostrobin, metrafenone, mildiomycin, myclobutanil, nabam, nitrothal-isopropyl, nuarimol, octhilinone, ofurace, oleic acid (fatty acids), orysastrobin, oxadixyl, oxathiapiprolin, oxine-copper, oxpoconazole fumarate, oxycarboxin, pefurazoate, penconazole, pencycuron, penflufen, pentachlorophenol, pentachlorophenyl laurate, penthiopyrad, phenylmercury acetate, phosphonic acid, phthalide, picarbutrazox, picoxystrobin, polyoxin B, polyoxins, polyoxorim, potassium bicarbonate, potassium hydroxyquinoline sulfate, probenazole, prochloraz, procymidone, propamocarb, propamocarb hydrochloride, propiconazole, propineb, proquinazid, prothioconazole, pydiflumetofen, pyrametostrobin, pyraoxystrobin, pyraclostrobin, pyraziflumid, pyrazophos, pyribencarb, pyributicarb, pyrifenox, pyrimethanil, pyriofenone, pyrisoxazole, pyroquilon, quinoclamine, quinoxyfen, quintozene, seboctylamine, sedaxane, silthiofam, simeconazole, sodium 2-phenylphenoxide, sodium bicarbonate, sodium pentachlorophenoxide, spiroxamine, sulfur, fungicidal sulfur derivatives, SYP-Z048, tar oils, tebuconazole, tebufloquin,tecnazene, tetraconazole, thiabendazole, thifluzamide, thiophanate-methyl, thiram, tiadinil, tolclofos-methyl, tolprocarb, tolylfluanid, triadimefon, triadimenol, triazoxide, tricyclazole, tridemorph, trifloxystrobin, triflumizole, triforine, triticonazole, validamycin, valifenalate, valiphenal, vinclozolin, zineb, ziram, zoxamide, (S)-N-(3,5-dichlorophenyl)-2-(methoxymethyl)-succinimide, 1,2-dichloropropane, l,3-dichloro-l,l,3,3-tetrafluoroacetone hydrate, l-chloro-2,4-dinitronaphthalene, l-chloro-2-nitropropane, 2-(2-heptadecyl-2-imidazolin-l-yl)ethanol, 2,3-dihydro-5-phenyl-l,4-dithi-ine 1,1,4,4-tetraoxide, 2-methoxyethylmercury acetate, 2-methoxyethylmercury chloride, 2-methoxyethylmercury silicate, 3-(4-chlorophenyl)-5-methylrhodanine, 4-(2-nitroprop- 1 -enyl)phenyl thiocyanateme, ampropylfos, anilazine, azithiram, barium polysulfide, Bayer 32394, benodanil, benquinox, bentaluron, benzamacril; benzamacril-isobutyl, benzamorf, binapacryl, bis(methylmercury) sulfate, bis(tributyltin) oxide, buthiobate, cadmium calcium copper zinc chromate sulfate, carbamorph, CECA, chlobenthiazone, chloraniformethan, chlorfenazole, chlorquinox, climbazole, copper bis(3-phenylsalicylate), copper zinc chromate, coumoxystrobin, cufraneb, cupric hydrazinium sulfate, cuprobam, cyclafuramid, cypendazole, cyprofuram, decafentin, dichlobentiazox, dichlone, dichlozoline, diclobutrazol, dimethirimol, dinocton, dinosulfon, dinoterbon, dipymetitrone, dipyrithione, ditalimfos, dodicin, drazoxolon, EBP, enoxastrobin, ESBP, etaconazole, etem, ethirim, fenaminstrobin, fenaminosulf, fenapanil, fenitropan, fenpicoxamid, florylpicoxamid, flufenoxystrobin, fluopimomide, fluotrimazole, furcarbanil, furconazole, furconazole-cis, furmecyclox, furophanate, glyodine, griseofulvin, halacrinate, Hercules 3944, hexylthiofos, ICIA0858, ipfentrifluconazole, ipflufenoquin, isopamphos, isovaledione, mandestrobin, mebenil, mecarbinzid, mefentrifluconazole, metazoxolon, methfuroxam, methylmercury dicyandiamide, metsulfovax, metyltetraprole, milneb, mucochloric anhydride, myclozolin, N-3,5-dichlorophenyl-succinimide, N-3-nitrophenylitaconimide, natamycin, N-ethylmercurio-4-toluenesulfonanilide, nickel bis(dimethyldithiocarbamate), OCH, phenylmercury dimethyldithiocarbamate, phenylmercury nitrate, phosdiphen, prothiocarb; prothiocarb hydrochloride, pyracarbolid, pyrapropoyne, pyridachlometyl, pyridinitril, pyrisoxazole, pyroxychlor, pyroxyfur, quinacetol; quinacetol sulfate, quinaminoprole, quinazamid, quinconazole, quinofumelin, rabenzazole, salicylanilide, SSF-109, sultropen,tecoram, thiadifluor, thicyofen, thiochlorfenphim, thiophanate, thioquinox, tioxymid, triamiphos, triarimol, triazbutil, trichlamide, triclopyricarb, triflumezopyrim, urbacid, zarilamid, Compound XI (also known as cyprometoxazam), Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6 (also known as metcyclofenstrobin), Compound X7, Compound X8, Compound X9, Compound X10, and any combinations thereof.5.3.2. Fungicidal Mixtures
[0187] In one aspect, the disclosure provides for a mixture wherein the mixture comprises the compound of Formula I and at least one additional fungicide compound.
[0188] In one aspect, the disclosure provides for a mixture wherein the mixture comprises the compound of Formula I and one additional fungicide compound.
[0189] In one aspect, the disclosure provides for a mixture wherein the mixture includes one additional fungicide compound, and wherein the one additional fungicide compound has a different mode of action from the compound of Formula I.
[0190] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and one additional fungicide wherein the additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cy proconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and bifemetstrobin, feneptamidoquin, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof.
[0191] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and one additional fungicide wherein the additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cy proconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and bifemetstrobin, feneptamidoquin, Compound XI, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and one additional fungicide wherein the additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin.
[0193] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and one additional fungicide wherein the additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and one additional fungicide wherein the additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and one additional fungicide wherein the additional fungicide is selected from thegroup consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cy proconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin.
[0196] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and one additional fungicide wherein the additional fungicide is selected from the group consisting of azoxystrobin, benzovindiflupyr, bixafen, cyproconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, mefentrifluconazole, metconazole, penthiopyrad, picoxystrobin, propiconazole, prothioconazole, pydiflumetofen, pyraclostrobin, tebuconazole, tetraconazole, trifloxystrobin, difenoconazole, flufenoxidiazam, folpet, fenpicoxamid, inpyrfluxam, isoflucypram, metyltetraprole, and proquinazid.
[0197] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and one additional fungicide wherein the additional fungicide is selected from the group consisting of azoxystrobin, benzovindiflupyr, bixafen, cyproconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, mefentrifluconazole, metconazole, penthiopyrad, picoxystrobin, propiconazole, prothioconazole, pydiflumetofen, pyraclostrobin, tebuconazole, tetraconazole, trifloxystrobin, difenoconazole, flufenoxidiazam, folpet, fenpicoxamid, inpyrfluxam, isoflucypram, metyltetraprole, and proquinazid.
[0198] In one aspect, the disclosure provides for a mixture comprising a compound of Formula I and two additional fungicides wherein each additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole,cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides for a mixture comprising a compound of Formula I-B and two additional fungicides wherein each additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides a fungicidal mixture comprising (a) a compound of Formula I and (b) acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin,fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides a fungicidal mixture comprising (a) a compound of Formula I-B and (b) at least one additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, and trifloxystrobin. In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is aminotipyr.
[0203] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is aminotipyr.
[0204] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is acibenzolar-S-methyl.
[0205] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is acibenzolar-S-methyl.
[0206] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is azoxystrobin.
[0207] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is azoxystrobin.
[0208] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is benzovindiflupyr.
[0209] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is benzovindiflupyr.
[0210] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is bifemetstrobin.
[0211] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is bifemetstrobin.
[0212] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is bixafen.
[0213] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is bixafen.
[0214] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is boscalid.
[0215] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is boscalid.
[0216] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is bupirimate.
[0217] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is bupirimate.
[0218] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is carmeconazole.
[0219] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is carmeconazole.
[0220] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is chlorothalonil.
[0221] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is chlorothalonil.
[0222] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is copper oxychloride.
[0223] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is copper oxychloride.
[0224] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is cyclobunofen.
[0225] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is cyclobunofen.
[0226] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is cyflufenamid.
[0227] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is cyflufenamid.
[0228] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is cyproconazole.
[0229] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is cyproconazole.
[0230] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is cyprodinil.
[0231] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is cyprodinil.
[0232] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is difenoconazole.
[0233] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is difenoconazole.
[0234] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is enprocymid.
[0235] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is enprocymid.
[0236] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is epoxiconazole.
[0237] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is epoxiconazole.
[0238] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is famoxadone.
[0239] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is famoxadone.
[0240] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fenbuconazole.
[0241] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fenbuconazole.
[0242] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is feneptamidoquin.
[0243] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is feneptamidoquin.
[0244] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fenpicoxamid.
[0245] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fenpicoxamid.
[0246] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fenpropidin.
[0247] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fenpropidin.
[0248] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fenpropimorph.
[0249] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fenpropimorph.
[0250] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is florylpicoxamid.
[0251] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is florylpicoxamid.
[0252] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluazinam.
[0253] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluazinam.
[0254] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fludioxonil.
[0255] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fludioxonil.
[0256] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is flufenoxadiazam.
[0257] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is flufenoxadiazam.
[0258] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluindapyr.
[0259] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluindapyr.
[0260] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluopyram.
[0261] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluopyram.
[0262] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is flutriafol.
[0263] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is flutriafol.
[0264] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is flumetylsulforim.
[0265] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is flumetylsulforim.
[0266] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluxapyroxad.
[0267] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluxapyroxad.
[0268] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluoxastrobin.
[0269] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluoxastrobin.
[0270] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is fluoxytioconazole.
[0271] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is fluoxytioconazole.
[0272] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is folpet.
[0273] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is folpet.
[0274] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is inpyrfluxam.
[0275] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is inpyrfluxam.
[0276] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is ipflufenoquin.
[0277] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is ipflufenoquin.
[0278] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is isofetamid.
[0279] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is isofetamid.
[0280] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is isoflucypram.
[0281] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is isoflucypram.
[0282] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is mancozeb.
[0283] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is mancozeb.
[0284] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is mefentrifluconazole.
[0285] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is mefentrifluconazole.
[0286] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is metarylpicoxamid.
[0287] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is metarylpicoxamid.
[0288] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is metconazole.
[0289] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is metconazole.
[0290] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is metominostrobin.
[0291] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is metominostrobin.
[0292] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is metrafenone.
[0293] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is metrafenone.
[0294] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is metyltetraprole.
[0295] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is metyltetraprole.
[0296] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is myclobutanil.
[0297] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is myclobutanil.
[0298] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is penconazole.
[0299] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is penconazole.
[0300] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is penthiopyrad.
[0301] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is penthiopyrad.
[0302] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is picoxystrobin.
[0303] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is picoxystrobin.
[0304] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is propiconazole.
[0305] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is propiconazole.
[0306] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is proquinazid.
[0307] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is proquinazid.
[0308] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is prothioconazole.
[0309] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is prothioconazole.
[0310] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pydiflumetofen.
[0311] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pydiflumetofen.
[0312] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pyraclostrobin.
[0313] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pyraclostrobin.
[0314] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pyrapropoyne.
[0315] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pyrapropoyne.
[0316] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pyraziflumid.
[0317] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pyraziflumid.
[0318] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pyridachlometyl.
[0319] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pyridachlometyl.
[0320] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is pyriofenone.
[0321] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is pyriofenone.
[0322] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is quinaminoprole.
[0323] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is quinaminoprole.
[0324] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is quinofumelin.
[0325] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is quinofumelin.
[0326] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is quinoxyfen.
[0327] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is quinoxyfen.
[0328] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is spiroxamine.
[0329] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is spiroxamine.
[0330] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is calcium polysulfide.
[0331] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is calcium polysulfide.
[0332] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is tebuconazole.
[0333] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is tebuconazole.
[0334] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is tetraconazole.
[0335] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is tetraconazole.
[0336] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is trifloxystrobin.
[0337] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is trifloxystrobin.
[0338] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound XI (also known as cy prometoxazam),.
[0339] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound XI (also known as cy prometoxazam),.
[0340] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X2.
[0341] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X2.
[0342] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X3.
[0343] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X3.
[0344] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X4a.
[0345] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X4a.
[0346] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X4b.
[0347] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X4b.
[0348] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X4c.
[0349] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X4c.
[0350] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X5.
[0351] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X5.
[0352] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X6 (also known as metcyclofenstrobin).
[0353] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X6 (also known as metcyclofenstrobin).
[0354] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X7.
[0355] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X7.
[0356] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X8.
[0357] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X8.
[0358] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X9.
[0359] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X9.
[0360] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and one additional fungicide which is Compound X10.
[0361] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and one additional fungicide which is Compound X10.
[0362] In one aspect, the disclosure provides for a mixture wherein the mixture comprises the compound of Formula I and two additional fungicide compounds.
[0363] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin.
[0364] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is selected from the group consisting of succinate dehydrogenase inhibitors (SDHI), sterol biosynthesis inhibitors (SBI), MET III Qi inhibitors, MET III Qoinhibitors, chemical multi-site inhibitors (MSI), and any combinations thereof.
[0365] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is a succinate dehydrogenase inhibitor (SDHI).
[0366] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is a sterol biosynthesis inhibitor (SBI).
[0367] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is a MET III Qi inhibitor.
[0368] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is a MET III Qoinhibitor.
[0369] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is a chemical multi-site inhibitor (MSI).
[0370] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is selected from the group consisting of azoxystrobin, benzovindiflupyr, cyproconazole, difenoconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, fluxapyroxad, inpyrfluxam, isoflucypram, mefentrifluconazole, metarylpicoxamid, metominostrobin, metyltetraprole, propiconazole, prothioconazole, pyraclostrobin, tebuconazole, tetraconazole, and trifloxystrobin.
[0371] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is azoxystrobin.
[0372] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is benzovindiflupyr.
[0373] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is propiconazole.
[0374] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is cyproconazole.
[0375] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is difenoconazole.
[0376] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is florylpicoxamid.
[0377] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is fluindapyr.
[0378] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is fluopyram.
[0379] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is flutriafol.
[0380] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is fluxapyroxad.
[0381] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is inpyrfluxam.
[0382] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is isoflucypram.
[0383] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is mefentrifluconazole.
[0384] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is metarylpicoxamid.
[0385] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is metominostrobin.
[0386] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is metyltetraprole.
[0387] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is prothioconazole.
[0388] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is pyraclostrobin.
[0389] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is tebuconazole.
[0390] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is tetraconazole.
[0391] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is picoxystrobin and the other is trifloxystrobin.
[0392] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad.
[0393] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is selected from the group consisting of succinate dehydrogenase inhibitors (SDHI), sterol biosynthesis inhibitors (SBI), MET III Qi inhibitors, MET III Qoinhibitors, chemical multi-site inhibitors (MSI), and any combinations thereof.
[0394] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is a succinate dehydrogenase inhibitor (SDHI).
[0395] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is a sterol biosynthesis inhibitor (SBI).
[0396] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is a MET III Qi inhibitor.
[0397] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is a MET III Qoinhibitor.
[0398] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is a chemical multi-site inhibitor (MSI).
[0399] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is selected from the group consisting of azoxystrobin, benzovindiflupyr, cyproconazole, difenoconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, inpyrfluxam, isoflucypram, mefentrifluconazole, metarylpicoxamid, metominostrobin, metyltetraprole, propiconazole, prothioconazole, pyraclostrobin, tebuconazole, tetraconazole, and trifloxystrobin.
[0400] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is azoxystrobin.
[0401] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is propiconazole.
[0402] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is cyproconazole.
[0403] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is difenoconazole.
[0404] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is florylpicoxamid.
[0405] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is fluindapyr.
[0406] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is fluopyram.
[0407] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is flutriafol.
[0408] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is inpyrfluxam.
[0409] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is isoflucypram.
[0410] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is mefentrifluconazole.
[0411] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is metarylpicoxamid.
[0412] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is metominostrobin.
[0413] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is metyltetraprole.
[0414] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is prothioconazole.
[0415] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is pyraclostrobin.
[0416] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is tebuconazole.
[0417] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is tetraconazole.
[0418] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is fluxapyroxad and the other is trifloxystrobin.
[0419] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen.
[0420] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is selected from the group consisting of succinate dehydrogenase inhibitors (SDHI),sterol biosynthesis inhibitors (SBI), MET III Qi inhibitors, MET III Qoinhibitors, chemical multi-site inhibitors (MSI), and any combinations thereof.
[0421] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is a succinate dehydrogenase inhibitor (SDHI).
[0422] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is a sterol biosynthesis inhibitor (SBI).
[0423] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is a MET III Qi inhibitor.
[0424] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is a MET III Qoinhibitor.
[0425] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is a chemical multi-site inhibitor (MSI).
[0426] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is selected from the group consisting of azoxystrobin, benzovindiflupyr, cyproconazole, difenoconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, fluxapyroxad, inpyrfluxam, isoflucypram, mefentrifluconazole, metarylpicoxamid, metominostrobin, metyltetraprole, picoxystrobin, propiconazole, prothioconazole, pyraclostrobin, tebuconazole, tetraconazole, and trifloxystrobin.
[0427] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is azoxystrobin.
[0428] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is benzovindiflupyr.
[0429] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is propiconazole.
[0430] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is cyproconazole.
[0431] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is difenoconazole.
[0432] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is florylpicoxamid.
[0433] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is fluindapyr.
[0434] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is fluopyram.
[0435] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is flutriafol.
[0436] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is fluxapyroxad.
[0437] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is inpyrfluxam.
[0438] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is isoflucypram.
[0439] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is mefentrifluconazole.
[0440] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is metarylpicoxamid.
[0441] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is metominostrobin.
[0442] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is metyltetraprole.
[0443] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is picoxystrobin.
[0444] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is prothioconazole.
[0445] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is pyraclostrobin.
[0446] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is tebuconazole.
[0447] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is tetraconazole.
[0448] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is pydiflumetofen and the other is trifloxystrobin.
[0449] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol.
[0450] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is selected from the group consisting of succinate dehydrogenase inhibitors (SDHI), sterol biosynthesis inhibitors (SBI), MET III Qi inhibitors, MET III Qoinhibitors, chemical multi-site inhibitors (MSI), and any combinations thereof.
[0451] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is a succinate dehydrogenase inhibitor (SDHI).
[0452] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is a sterol biosynthesis inhibitor (SBI).
[0453] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is a MET III Qi inhibitor.
[0454] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is a MET III Qoinhibitor.
[0455] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is a chemical multi-site inhibitor (MSI).
[0456] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is selected from the group consisting of azoxystrobin, benzovindiflupyr, cyproconazole, difenoconazole, florylpicoxamid, fluindapyr, fluopyram, inpyrfluxam, isoflucypram, mefentrifluconazole, metarylpicoxamid, metominostrobin, metyltetraprole, propiconazole, prothioconazole, pyraclostrobin, tebuconazole, tetraconazole, and trifloxystrobin.
[0457] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is azoxystrobin.
[0458] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is benzovindiflupyr.
[0459] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is propiconazole.
[0460] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is cyproconazole.
[0461] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is difenoconazole.
[0462] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is florylpicoxamid.
[0463] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is fluindapyr.
[0464] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is fluopyram.
[0465] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is inpyrfluxam.
[0466] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is isoflucypram.
[0467] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is mefentrifluconazole.
[0468] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is metarylpicoxamid.
[0469] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is metominostrobin.
[0470] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is metyltetraprole.
[0471] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is prothioconazole.
[0472] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is pyraclostrobin.
[0473] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is tebuconazole.
[0474] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is tetraconazole.
[0475] In one aspect, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein one additional fungicide is flutriafol and the other is trifloxystrobin.5.3.3. Ranges / Concentrations
[0476] In one aspect, the mixtures disclosed herein are present at a weight ratio of a compound of Formula I to the at least one additional fungicide that exhibits enhanced efficacy.
[0477] In one aspect, the mixtures disclosed herein are present at a weight ratio of a compound of Formula I-B to the at least one additional fungicide that exhibits enhanced efficacy.
[0478] In various aspects, at least one additional fungicide and a compound of Formula I in the composition may be used in a wide variety of weight ratios. For example, in a two-component mixture, the weight ratio of a compound of Formula I to an active ingredient, the weight ratios in Table Al may be used. However, in general, weight ratios less than about 10:1 to about 1: 10 are preferred.
[0479] In various aspects, at least one additional fungicide and a compound of Formula I-B in the composition may be used in a wide variety of weight ratios. For example, in a two-component mixture, the weight ratio of a compound of Formula I-B to an active ingredient, the weight ratios in Table A2 may be used. However, in general, weight ratios less than about 10: 1 to about 1: 10 are preferred.
[0480] Weight ratios of a mixture of a compound of Formula I to another active ingredient may also be depicted as X: Y; wherein X is the parts by weight of a compound of Formula I and Y is the parts by weight of the active ingredient. The numerical range of the parts by weight for X is 0 < X < 100 and the parts by weight for Y is 0 < Y < 100 and is shown graphically in Table Bl. By way of non-limiting example, the weight ratio of a compound of Formula I to an active ingredient may be 20: 1.
[0481] Ranges of weight ratios of a compound of Formula I to an active ingredient may be depicted as X1:Y1 to X2:Y2, wherein X and K are defined as above.
[0482] Weight ratios of a mixture of a compound of Formula I-B to another active ingredient may also be depicted as X: Y; wherein X is the parts by weight of a compound of Formula I-B and Y is the parts by weight of the active ingredient. The numerical range of the parts by weight for X is 0 < X < 100 and the parts by weight for Y is 0 < Y < 100 and is shown graphically in Table B2. By way of non-limiting example, the weight ratio of a compound of Formula I-B to an active ingredient may be 20: 1.
[0483] Ranges of weight ratios of a compound of Formula I-B to an active ingredient may be depicted as X1:Y1 to X2:Y2, wherein X and Y are defined as above.
[0484] In one embodiment, the range of weight ratios may beXr. Yi to X2X2, wherein Xi > Yi and X2 < Y2. By way of non-limiting example, the range of a weight ratio of Formula I to an active ingredient may be between 3: 1 and 1:3, inclusive of the endpoints. By way of nonlimiting example, the range of a weight ratio of Formula I-B to an active ingredient may be between 3:1 and 1:3, inclusive of the endpoints.
[0485] In another embodiment, the range of weight ratios may be X1:Y1 to X2:Y2, wherein X1 > Y2. By way of non-limiting example, the range of weight ratio of Formula I to an active ingredient may be between 15:1 and 3:1, inclusive of the endpoints. By way of nonlimiting example, the range of weight ratio of Formula I-B to an active ingredient may be between 15:1 and 3:1, inclusive of the endpoints.
[0486] In another embodiment, the range of weight ratios may eXiXi to X2X2, wherein Xi < Yi and X2 < Y2. By way of non-limiting example, the range of weight ratios of Formula I to an active ingredient may be between about 1:3 and about 1:20, inclusive of the endpoints. By way of non-limiting example, the range of weight ratios of Formula I-B to an active ingredient may be between about 1:3 and about 1:20, inclusive of the endpoints.
[0487] In various aspects, each one of the at least one additional fungicide and also the compound of Formula I in the composition is present at a concentration of 10 nanogram per milliliter (ng / mL), 50 ng / mL, 100 ng / mL, 500 ng / mL, 1 microgram per milliliter (ug / mL), 10 ug / mL, 50 ug / mL, 75 ug / mL, 0.1 milligram per milliliter (mg / mL), 0.2 mg / mL, 0.3 mg / mL, 0.4 mg / mL, even 0.5 mg / mL. In various aspects, each one of the at least one additional fungicide and also the compound of Formula I-B in the composition is present at a concentration of 10 ng / mL, 50 ng / mL, 100 ng / mL, 500 ng / mL, 1 ug / mL, 10 ug / mL, 50 ug / mL, 75 ug / mL, 0.1 mg / mL, 0.2 mg / mL, 0.3 mg / mL, 0.4 mg / mL, even 0.5 mg / mL. In some aspects, at least one additional fungicide and a compound of Formula I in the composition is present at a concentration of 1 mg / mL, 2 mg / mL, 3 mg / mL, 4 mg / mL or 5 mg / mL. In some aspects, at least one additional fungicide and a compound of Formula I-B in the composition is present at a concentration of 1 mg / mL, 2 mg / mL, 3 mg / mL, 4 mg / mL or 5 mg / mL. In some aspects, at least one additional fungicide and also the compound of Formula I in the composition is present at a concentration of 10 mg / mL, 20 mg / mL, 30 mg / mL, 40 mg / mL or 50 mg / mL. In some aspects, at least one additional fungicide and also the compound of Formula I-B in the composition is present at a concentration of 10 mg / mL, 20 mg / mL, 30 mg / mL, 40 mg / mL or 50 mg / mL. In some aspects, at least one additional fungicide and a compound of Formula I in the composition is present at a concentration of at least 100 mg / mL, 125 mg / mL, 150 mg / mL, 175 mg / mL, or 200 mg / mL. In some aspects, at least one additional fungicide and a compound of Formula I-B in thecomposition is present at a concentration of at least 100 mg / mL, 125 mg / mL, 150 mg / mL, 175 mg / mL, or 200 mg / mL.
[0488] In some other aspects, at least one additional fungicide and a compound of Formula I in the composition is present at a concentration of at least 250 mg / mL. In some other aspects, at least one additional fungicide and a compound of Formula LB in the composition is present at a concentration of at least 250 mg / mL.
[0489] In some other aspects, at least one additional fungicide and a compound of Formula I in the composition is present at a concentration from 0.1 mg / mL to 0.01 mg / mL. In some other aspects, at least one additional fungicide and a compound of Formula LB in the composition is present at a concentration from 0.1 mg / mL to 0.01 mg / mL.
[0490] In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 1: 100. In certain aspects, the weight ratio of the compound of Formula LB to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 1:100.
[0491] In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 10: 1. In certain aspects, the weight ratio of the compound of Formula LB to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 10:1.
[0492] In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 2:1. In certain aspects, the weight ratio of the compound of Formula LB to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 2: 1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 3:1. In certain aspects, the weight ratio of the compound of Formula LB to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 3: 1. In certain aspects, the weight ratio of the compound of Formula I to each additionalfungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 4:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 4: 1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 5:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 5:1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 6:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 6: 1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 7:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 7:1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 8:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 8: 1. In certain aspects, the weight ratio of the compound of Formula I to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 9:1. In certain aspects, the weight ratio of the compound of Formula I-B to each additional fungicide at which the fungicidal effect is lies within the range of between about 1: 1 and about 9:1.
[0493] In some aspects the fungicidal compositions described herein may comprise, with respect to the composition, from about 1 gram active ingredient per liter (g ai / L) to about 10 kilograms active ingredient per liter (kg ai / L), from about 5 g ai / L to about 10 kg ai / L, from about 10 g ai / L to about 10 kg ai / L, from about 20 g ai / L to about 10 kg ai / L, from about 25 g ai / L to about 10 kg ai / L, from about 30 g ai / L to about 10 kg ai / L, from about 40 g ai / L to about10 kg ai / L, from about 25 g ai / L to about 10 kg ai / L, from about 50 g ai / L to about 10 kg ai / L, from about 60 g ai / L to about 10 kg ai / L, from about 70 g ai / L to about 10 kg ai / L, from about 80 g ai / L to about 10 kg ai / L, from about 90 g ai / L to about 10 kg ai / L, from about 100 g ai / L to about 10 kg ai / L, from about 200 g ai / L to about 10 kg ai / L, from about 500 g ai / L to about 10 kg ai / L, from about 750 g ai / L to about 10 kg ai / L, of the compound of Formula I. In some aspects the fungicidal compositions described herein may comprise, with respect to the composition, from about 1 gram active ingredient per liter (g ai / L) to about 10 kilograms active ingredient per liter (kg ai / L), from about 5 g ai / L to about 10 kg ai / L, from about 10 g ai / L to about 10 kg ai / L, from about 20 g ai / L to about 10 kg ai / L, from about 25 g ai / L to about 10 kg ai / L, from about 30 g ai / L to about 10 kg ai / L, from about 40 g ai / L to about 10 kg ai / L, from about 25 g ai / L to about 10 kg ai / L, from about 50 g ai / L to about 10 kg ai / L, from about 60 g ai / L to about 10 kg ai / L, from about 70 g ai / L to about 10 kg ai / L, from about 80 g ai / L to about 10 kg ai / L, from about 90 g ai / L to about 10 kg ai / L, from about 100 g ai / L to about 10 kg ai / L, from about 200 g ai / L to about 10 kg ai / L, from about 500 g ai / L to about 10 kg ai / L, from about 750 g ai / L to about 10 kg ai / L, of the compound of Formula LB.
[0494] In one aspect,, the disclosure provides for a mixture containing a compound of Formula I and two additional fungicides wherein the weight ratio of the compound of Formula I to one additional fungicide may be from 10:1 to 1:10; and the weight ratio of the compound of Formula I to the other additional fungicide may be from 100: 1 to 1: 100, from 95: 1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5.
[0495] In one aspect, the disclosure provides for a mixture containing a compound of Formula I-B and two additional fungicides wherein the weight ratio of the compound of Formula I-B to the one additional fungicide may be from 10: 1 to 1: 10; and the weight ratio of the compound of Formula I-B to the other additional fungicide may be from 100: 1 to 1: 100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5.
[0496] In one aspect, the weight ratio of (a) the compound of Formula I to (b) an at least one additional fungicide may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) an at least one additional fungicide may be 1:1.
[0497] In one aspect, the weight ratio of (a) the compound of Formula I-B to (b) an at least one additional fungicide may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I-B to (b) an at least one additional fungicide may be 1:1.
[0498] In one aspect, the weight ratio of (a) the compound of Formula I to (b) aminotipyr may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) aminotipyr may be 1:1.
[0499] In one aspect, the weight ratio of (a) the compound of Formula I to (b) acibenzolar-S-methyl may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) acibenzolar-S-methyl may be 1: 1.
[0500] In one aspect, the weight ratio of (a) the compound of Formula I to (b) azoxystrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) azoxystrobin may be 1:1.
[0501] In one aspect, the weight ratio of (a) the compound of Formula I to (b) benzovindiflupyr may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) benzovindiflupyr may be 1:1.
[0502] In one aspect, the weight ratio of (a) the compound of Formula I to (b) bifemetstrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) bifemetstrobin may be 1:1.
[0503] In one aspect, the weight ratio of (a) the compound of Formula I to (b) bixafen may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) bixafen may be 1:1.
[0504] In one aspect, the weight ratio of (a) the compound of Formula I to (b) boscalid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) boscalid may be 1:1.
[0505] In one aspect, the weight ratio of (a) the compound of Formula I to (b) bupirimate may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) bupirimate may be 1:1.
[0506] In one aspect, the weight ratio of (a) the compound of Formula I to (b) carmeconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1: 2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) carmeconazole may be 1:1.
[0507] In one aspect, the weight ratio of (a) the compound of Formula I to (b) chlorothalonil may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10,from 3: 1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) chlorothalonil may be 1:1.
[0508] In one aspect, the weight ratio of (a) the compound of Formula I to (b) copper oxychloride may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) copper oxychloride may be 1:1.
[0509] In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyclobunofen may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyclobunofen may be 1:1.
[0510] In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyflufenamid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyflufenamid may be 1:1.
[0511] In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyproconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyproconazole may be 1:1.
[0512] In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyprodinil may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) cyprodinil may be 1:1.
[0513] In one aspect, the weight ratio of (a) the compound of Formula I to (b) difenoconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) difenoconazole may be 1:1.
[0514] In one aspect, the weight ratio of (a) the compound of Formula I to (b) enprocymid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) enprocymid may be 1:1.
[0515] In one aspect, the weight ratio of (a) the compound of Formula I to (b) epoxiconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) epoxiconazole may be 1:1.
[0516] In one aspect, the weight ratio of (a) the compound of Formula I to (b) famoxadone may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) famoxadone may be 1:1.
[0517] In one aspect, the weight ratio of (a) the compound of Formula I to (b) feneptomidoquin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) feneptomidoquin may be 1:1.
[0518] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenbuconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10,from 3: 1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenbuconazole may be 1:1.
[0519] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpicoxamid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpicoxamid may be 1:1.
[0520] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpropidin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpropidin may be 1:1.
[0521] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpropimorph may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fenpropimorph may be 1:1.
[0522] In one aspect, the weight ratio of (a) the compound of Formula I to (b) florylpicoxamid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) florylpicoxamid may be 1:1.
[0523] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluazinam may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluazinam may be 1:1.
[0524] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fludioxonil may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fludioxonil may be 1:1.
[0525] In one aspect, the weight ratio of (a) the compound of Formula I to (b) flufenoxadiazam may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) flufenoxadiazam may be 1:1.
[0526] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluindapyr may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluindapyr may be 1:1.
[0527] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluopyram may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluopyram may be 1:1.
[0528] In one aspect, the weight ratio of (a) the compound of Formula I to (b) flutriafol may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1: 2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) flutriafol may be 1:1.
[0529] In one aspect, the weight ratio of (a) the compound of Formula I to (b)flumetylsulforim may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) flumetylsulforim may be 1:1.
[0530] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluxapyroxad may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluxapyroxad may be 1:1.
[0531] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluoxytioconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluoxytioconazole may be 1:1.
[0532] In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluoxastrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) fluoxastrobin may be 1:1.
[0533] In one aspect, the weight ratio of (a) the compound of Formula I to (b) folpet may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) folpet may be 1:1.
[0534] In one aspect, the weight ratio of (a) the compound of Formula I to (b) inpyrfluxam may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) inpyrfluxam may be 1:1.
[0535] In one aspect, the weight ratio of (a) the compound of Formula I to (b) ipflufenoquin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) ipflufenoquin may be 1:1.
[0536] In one aspect, the weight ratio of (a) the compound of Formula I to (b) isofetamid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) isofetamid may be 1:1.
[0537] In one aspect, the weight ratio of (a) the compound of Formula I to (b) isoflucypram may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) isoflucypram may be 1:1.
[0538] In one aspect, the weight ratio of (a) the compound of Formula I to (b) mancozeb may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) mancozeb may be 1:1.
[0539] In one aspect, the weight ratio of (a) the compound of Formula I to (b) mefentrifluconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) mefentrifluconazole may be 1:1.
[0540] In one aspect, the weight ratio of (a) the compound of Formula I to (b) metarylpicoxamid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) metarylpicoxamid may be 1:1.
[0541] In one aspect, the weight ratio of (a) the compound of Formula I to (b) metconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) metconazole may be 1:1.
[0542] In one aspect, the weight ratio of (a) the compound of Formula I to (b) metominostrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) metominostrobin may be 1:1.
[0543] In one aspect, the weight ratio of (a) the compound of Formula I to (b) metrafenone may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) metrafenone may be 1:1.
[0544] In one aspect, the weight ratio of (a) the compound of Formula I to (b) metyltetraprole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) metyltetraprole may be 1:1.
[0545] In one aspect, the weight ratio of (a) the compound of Formula I to (b) myclobutanil may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) myclobutanil may be 1:1.
[0546] In one aspect, the weight ratio of (a) the compound of Formula I to (b) penconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) penconazole may be 1:1.
[0547] In one aspect, the weight ratio of (a) the compound of Formula I to (b) penthiopyrad may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) penthiopyrad may be 1:1.
[0548] In one aspect, the weight ratio of (a) the compound of Formula I to (b) picoxystrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) picoxystrobin may be 1:1.
[0549] In one aspect, the weight ratio of (a) the compound of Formula I to (b) propiconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) propiconazole may be 1:1.
[0550] In one aspect, the weight ratio of (a) the compound of Formula I to (b) proquinazid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1: 2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) proquinazid may be 1:1.
[0551] In one aspect, the weight ratio of (a) the compound of Formula I to (b) prothioconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) prothioconazole may be 1:1.
[0552] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pydiflumetofen may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pydiflumetofen may be 1:1.
[0553] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyraclostrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyraclostrobin may be 1:1.
[0554] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyrapropoyne may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyrapropoyne may be 1:1.
[0555] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyraziflumid may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyraziflumid may be 1:1.
[0556] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyridachlometyl may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyridachlometyl may be 1:1.
[0557] In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyriofenone may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) pyriofenone may be 1:1.
[0558] In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinaminoprole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinaminoprole may be 1:1.
[0559] In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinofumelin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinofumelin may be 1:1.
[0560] In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinoxyfen may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) quinoxyfen may be 1:1.
[0561] In one aspect, the weight ratio of (a) the compound of Formula I to (b) spiroxamine may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1: 2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) spiroxamine may be 1:1.
[0562] In one aspect, the weight ratio of (a) the compound of Formula I to (b) calcium polysulfide may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,Illfrom 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) calcium poly sulfide may be 1:1.
[0563] In one aspect, the weight ratio of (a) the compound of Formula I to (b) tebuconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) tebuconazole may be 1:1.
[0564] In one aspect, the weight ratio of (a) the compound of Formula I to (b) tetraconazole may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) tetraconazole may be 1:1.
[0565] In one aspect, the weight ratio of (a) the compound of Formula I to (b) trifloxystrobin may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) trifloxystrobin may be 1:1.
[0566] In one aspect, the weight ratio of (a) the compound of Formula I to (b) one of the compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, or Compound X10 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2,from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) one of the compounds of Formula X-A, compounds of Formula X-B, compounds of Formula X-C, compounds of Formula X-D, compounds of Formula X-F, compounds of Formula X-G, compounds of Formula X-H, compounds of Formula X-J, compounds of Formula X-K, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, or Compound X10 may be 1:1.
[0567] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X1 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X1 may be 1:1.
[0568] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X2 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15,from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X2 may be 1:1.
[0569] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X3 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1: 2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X3 may be 1:1.
[0570] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4a may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4a may be 1:1.
[0571] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4b may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4b may be 1:1.
[0572] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4c may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X4c may be 1:1.
[0573] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X5 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X5 may be 1:1.
[0574] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X6 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X6 may be 1:1.
[0575] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X7 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X7 may be 1:1.
[0576] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X8 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X8 may be 1:1.
[0577] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X9 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3: 1 to 1:2, or from 2: 1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X9 may be 1:1.
[0578] In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X10 may be from 100:1 to 1:100, from 95:1 to 1:95, from 90:1 to 1:90, from 85:1 to 1:85, from 80:1 to 1:80, from 75:1 to 1:75, from 70:1 to 1:70, from 65:1 to 1:65, from 60:1 to 1:60, from 55:1 to 1:55, from 50:1 to 1:50, from 45:1 to 1:45, from 40:1 to 1:40, from 35:1 to 1:35, from 30:1 to 1:30, from 25:1 to 1:25, from 20:1 to 1:20, from 15:1 to 1:15, from 10:1 to 1:10, from 5:1 to 1:5, from 4:1 to 1:4, from 3:1 to 1:3, from 2:1 to 1:2, from 30:1 to 1:50, from 30:1 to 1:40, from 30:1 to 1:20, from 30:1 to 1:10, from 30:1 to 1:5, from 25:1 to 1:45, from 25:1 to 1:35, from 25:1 to 1:15, from 25:1 to 1:5, from 20:1 to 1:40, from 20:1 to 1:30, from 20:1 to 1:10, from 20:1 to 1:5, from 15:1 to 1:35, from 15:1 to 1:25, from 15:1 to 1:5, from 12:1 to 1:25, from 12:1 to 1:15, from 12:1 to 1:5, from 12:1 to 1:2, from 10:1 to 1:20, from 10:1 to 1:8, from 10:1 to 1:5, from 10:1 to 1:2, from 5:1 and 1:15, from 5:1 to 1:8, from 5:1 to 1:4, from 5:1 to 1:2, from 3:1 to 1:10, from 3:1 to 1:8, from 3:1 to 1:2, or from 2:1 to 1:5. In one aspect, the weight ratio of (a) the compound of Formula I to (b) Compound X10 may be 1:1.
[0579] In one aspect, the mixtures disclosed herein are present in an amount that exhibits enhanced efficacy.5.3.4. Formulations
[0580] In one aspect, the disclosure provides for a fungicidal composition comprising a fungicidally effective amount of any one of the mixtures of any one of the previous aspects and an agriculturally acceptable carrier.
[0581] In one aspect, the disclosure provides for a fungicidal composition comprising a fungicidally effective amount of the compound of Formula I and an agriculturally acceptable carrier.
[0582] In one aspect, the disclosure provides for a fungicidal composition comprising a fungicidally effective amount of the compound of Formula I-B and an agriculturally acceptable carrier.
[0583] In one aspect, the disclosure provides for a fungicidal composition comprising a fungicidally effective amount of any one of the mixtures of any one of the previous aspects and an agriculturally acceptable carrier.
[0584] In one aspect, the mixtures disclosed herein are present at a weight ratio of a compound of Formula I to the at least one additional fungicide that exhibits enhanced efficacy in the composition.
[0585] In one aspect, the mixtures disclosed herein are present at a weight ratio of a compound of Formula I-B to the at least one additional fungicide that exhibits enhanced efficacy in the composition.
[0586] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and bifemetstrobin, feneptamidoquin, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof, together with a phytologically acceptable carrier.
[0587] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I-B and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and bifemetstrobin, feneptamidoquin, Compound X1, Compound X2, Compound X3, Compound X4a, Compound X4b, Compound X4c, Compound X5, Compound X6, Compound X7, Compound X8, Compound X9, Compound X10, and mixtures thereof, together with a phytologically acceptable carrier.
[0588] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone,quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and mixtures thereof, together with a phytologically acceptable carrier.
[0589] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I-B and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyl tetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and mixtures thereof, together with a phytologically acceptable carrier.
[0590] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, quinofumelin, quinoxyfen, spiroxamine, calciumpolysulfide, tebuconazole, tetraconazole, trifloxystrobin, and mixtures thereof, together with a phytologically acceptable carrier.
[0591] The compositions of the present disclosure are preferably applied in the form of a formulation comprising a composition of (a) a compound of Formula I-B and (b) an additional fungicide selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, flumetylsulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole, metarylpicoxamid, metconazole, metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and mixtures thereof, together with a phytologically acceptable carrier.
[0592] The present disclosure contemplates all vehicles by which the mixtures of this disclosure may be formulated for delivery and used as a fungicide. Typically, formulations are applied to plant foliage or to the root system, or the surrounding soil, or even to a seed, as aqueous suspensions or emulsions. Such suspensions or emulsions may be produced from water-soluble, water-suspendible, or emulsifiable formulations which are solids, usually known as wettable powders; or liquids, usually known as emulsifiable concentrates (EC), aqueous suspensions, or suspension concentrates (SC). Moreover, formulations such as suspensions (OD, FS), pastes, pastilles and gel formulations are within the scope of the compositions disclosed herein. In some aspects, the composition is diluted. In some aspects, the composition is undiluted.
[0593] As will be readily appreciated, any material to which any fungicide mixture of this disclosure can be added may be used, provided they yield the desired utility without significant interference with the activity of these compositions as antifungal agents.
[0594] Concentrated formulations may be dispersed in water, or other liquids, for application, or formulations may be dust-like or granular, which may then be applied without further treatment. The formulations can be prepared according to procedures that are known and conventional in the agricultural chemical art. Methods to make and use agricultural compositions comprising the compound of Formula I and at least one additional fungicide can be found in, for example, references such as, Hance et al. Weed Control Handbook (8th ed., Blackwell Scientific, Oxford, 1989); Mollet, H. and Grubenmann, A.: Formulation Technology: Emulsions, Suspensions, Solid Forms (Wiley VCH Verlag, Weinheim, 2001); Perry's Chemical Engineers' Handbook (4th ed., McGraw-Hill, New York, 1963); Browning, et al. "Agglomeration" in Chemical Engineering, Dec. 4, 1967, 147-48; Klingman, Weed Control as a Science (J. Wiley & Sons, New York, 1961); and US 3,060,084, US 3,299,566, US 4,172,714, US 4,144,050, US 3,920,442, US 5,180,587, US 5,232,701, US 5,208,030, EP 707445, GB 2,095,558, and WO9113546, each of which is incorporated by reference in its entirety.
[0595] Wettable powders, which may be compacted to form water-dispersible granules, comprise a fungicide mixture of this disclosure, a carrier and agriculturally acceptable surfactants. The concentration of the fungicide mixture in the wettable powder is usually from about 10% to about 90% by weight, more preferably about 25% to about 75% by weight, based on the total weight of the formulation. In the preparation of wettable powder formulations, the fungicide mixture can be compounded with any of the finely divided solids, such as prophyllite, talc, chalk, gypsum, Fuller's earth, bentonite, attapulgite, starch, casein, gluten, montmorillonite clays, diatomaceous earths, purified silicates or the like. In such operations, the finely divided carrier is ground or mixed with the composition in a volatile organic solvent. Effective surfactants, comprising from about 0.5% to about 10% by weight of the wettable powder, include sulfonated lignins, naphthalenesulfonates, alkylbenzenesulfonates, alkyl sulfates, and nonionic surfactants, such as ethylene oxide adducts of alkyl phenols.
[0596] Some aspects of the disclosure provide a fungicidal composition - in any of the aspects described herein comprising a compound of Formula I and any at least one additional fungicide - formulated in a composition of an emulsifiable concentrate (i.e., an emulsion concentrate or EC) that contains an effective amount of the compound of Formula I.
[0597] Some aspects of the disclosure provide a fungicidal composition - in any of the aspects described herein comprising a compound of Formula I-B and any at least one additional fungicide - formulated in a composition of an emulsifiable concentrate (i.e., an emulsion concentrate or EC) that contains an effective amount of the compound of Formula I-B.
[0598] Emulsifiable concentrates of a fungicide mixture of this disclosure comprise a convenient concentration of the fungicide mixture, such as from about 1% to about 50% by weight, in a suitable liquid, based on the total weight of the emulsifiable concentrate formulation. The components of the fungicide mixture, jointly or separately, are dissolved in a carrier, which is either a water-miscible solvent or a mixture of water-immiscible organic solvents, and emulsifiers. The concentrates may be diluted with water and oil to form spray mixtures in the form of oil-in-water emulsions.
[0599] Emulsifiers which can be advantageously employed herein can be readily determined by those skilled in the art and include various nonionic, anionic, cationic and amphoteric emulsifiers, or a blend of two or more emulsifiers. Examples of nonionic emulsifiers useful in preparing the emulsifiable concentrates include the polyalkylene glycol ethers and condensation products of alkyl and aryl phenols, aliphatic alcohols, aliphatic amines or fatty acids with ethylene oxide, propylene oxides such as the ethoxylated alkyl phenols and carboxylic esters solubilized with the polyol or polyoxyalkylene. Cationic emulsifiers include quaternary ammonium compounds and fatty amine salts. Anionic emulsifiers include the oil-soluble salts (e g., calcium) of alkylaryl sulfonic acids, oil-soluble salts or sulfated polyglycol ethers and appropriate salts of phosphated polyglycol ether.
[0600] Representative organic liquids which can be employed in preparing the emulsifiable concentrates of the present disclosure are the aromatic liquids such as xylene, propyl benzene fractions, or mixed naphthalene fractions, mineral oils, substituted aromatic organic liquids such as dioctyl phthalate, kerosene, dialkyl amides of various fatty acids, particularly the dimethyl amides of fatty glycols and glycol derivatives such as the n-butyl ether, ethyl ether or methyl ether of diethylene glycol, and the methyl ether of triethylene glycol. Mixtures of two or more organic liquids are also often suitably employed in the preparation of the emulsifiable concentrate. The preferred organic liquids are xylene, and propyl benzene fractions, with xylenebeing most preferred. The surface-active dispersing agents are usually employed in liquid formulations and in the amount of from 0.1 to 20 percent by weight of the combined weight of the dispersing agent with the compositions. The formulations can also contain other compatible additives, for example, plant growth regulators and other biologically active compounds used in agriculture.
[0601] Aqueous suspensions comprise suspensions of one or more water-insoluble compounds, dispersed in an aqueous vehicle at a concentration in the range from about 5% to about 70% by weight, based on the total weight of the aqueous suspension formulation.Suspensions are prepared by finely grinding the components of the mixture either together or separately, and vigorously mixing the ground material into a vehicle comprised of water and surfactants chosen from the same types discussed above. Other ingredients, such as inorganic salts and synthetic or natural gums, may also be added to increase the density and viscosity of the aqueous vehicle. It is often most effective to grind and mix at the same time by preparing the aqueous mixture and homogenizing it in an implement such as a sand mill, ball mill, or pistontype homogenizer.
[0602] The composition may also be applied as a granular formulation, which is particularly useful for applications to the soil. Granular formulations usually contain from about 0.5% to about 70% by weight of the fungicides, based on the total weight of the granular formulation, dispersed in a carrier which consists entirely or in large part of coarsely divided attapulgite, bentonite, diatomite, clay or a similar inexpensive substance. Such formulations are usually prepared by dissolving the fungicide mixture in a suitable solvent and applying it to a granular carrier which has been pre-formed to the appropriate particle size, in the range of from about 0.5 to about 3 millimeters (mm). Such formulations may also be prepared by making a dough or paste of the carrier and the composition and crushing and drying to obtain the desired granular particle.
[0603] Dusts containing the fungicide mixtures are prepared simply by intimately mixing the mixture in powdered form with a suitable dusty agricultural carrier, such as, for example, kaolin clay, ground volcanic rock, and the like. Dusts can suitably contain from about 1% to about 70% by weight of the fungicide mixture / carrier combination.
[0604] The formulations may contain agriculturally acceptable adjuvant surfactants to enhance deposition, wetting and penetration of the composition onto the target crop and organism. These adjuvant surfactants may optionally be employed as a component of the formulation or as a tank mix. The amount of adjuvant surfactant will vary from 0.01 percent to 1.0 percent volume / volume (v / v) based on a spray -volume of water, preferably 0.05 to 0.5 percent. Suitable adjuvant surfactants include ethoxylated nonyl phenols, ethoxylated synthetic or natural alcohols, salts or the esters of sulfosuccinic acids, ethoxylated organosilicones, ethoxylated fatty amines and blends of surfactants with mineral or vegetable oils.
[0605] In one aspect, the composition comprises a mixture comprising a compound of Formula I and at least one additional fungicide. In one aspect, the composition comprises the mixture of at least one of the additional fungicide and the compound of Formula I and a phytologically acceptable carrier. Preferably, the mixture of at least one of the additional fungicide and the compound of Formula I of the present disclosure are applied in the form of a composition.
[0606] In various aspects, the phytologically acceptable carrier includes, but is not limited to, one or more of: solvents, dispersants, emulsifiers e.g. solubilizers, protective colloids, surfactants and adhesion agents, organic and inorganic thickeners, bactericides, anti-freezing agents, antifoaming agents, if appropriate colorants and tackifiers or binders (e.g. for seed treatment formulations).
[0607] In this context, suitable solvents for a formulation include water, alcohols such as methanol, ethanol, propanol, butanol or cyclohexanol, glycols, ketones such as cyclohexanone and gamma-butyrolactone, or a solvent such as mineral oil fractions of medium to high boiling point, kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e.g. toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes or their alkylated naphthalene derivatives, or a fatty acid or fatty acid dimethylamides, fatty acid esters and strongly polar solvents, e.g. amines such as N- methylpyrrolidone.
[0608] In various aspects, the phytologically acceptable carrier(s) is liquid. In various aspects, the phytologically acceptable carrier(s) is solid. In such aspects, a solid carrier mayinclude, but is not limited to, magnesium sulfate, magnesium oxide, silicates, silica gels, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, talc, kaolins, limestone, calcium sulfate, fertilizers, such as, e.g., ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and materials such of like of corn meal, tree bark meal, wood meal and nutshell meal, and cellulose powders.
[0609] The formulations may additionally contain other phytologically acceptable carriers, such as adjuvant surfactants to enhance deposition, wetting, and penetration of the compounds onto the target crop and organism. These adjuvant surfactants may optionally be employed as a component of the formulation or as a tank mix. The amount of adjuvant surfactant will typically vary from 0.01 to 1.0 percent by volume, based on a spray -volume of water, preferably 0.05 to 0.5 volume percent. Suitable adjuvant surfactants include, but are not limited to ethoxylated nonyl phenols, ethoxylated synthetic or natural alcohols, salts or the esters of sulfosuccinic acids, ethoxylated organosilicones, ethoxylated fatty amines, blends of surfactants with mineral or vegetable oils, crop oil concentrate (mineral oil (85%) + emulsifiers (15%)); nonylphenol ethoxylate; benzylcocoalkyldimethyl quaternary ammonium salt; blend of petroleum hydrocarbon, alkyl esters, organic acid, and anionic surfactant; C9 - Cl 1 alkylpolyglycoside; phosphated alcohol ethoxylate; natural primary alcohol (C12 - C16) ethoxylate; di-sec-butylphenol EO-PO block copolymer; polysiloxane-methyl cap; nonylphenol ethoxylate + urea ammonium nitrate; emulsified methylated seed oil; tridecyl alcohol (synthetic) ethoxylate (8EO); tallow amine ethoxylate (15 EO); PEG(400) dioleate-99. These types of formulations may also include oil-in-water emulsions, such are described, and the procedures to make them are explained in U. S. Patent Application Serial No. 11 / 495,228, the disclosure of which is hereby incorporated in its entirety by reference herein.
[0610] Bactericides may be added for preservation and stabilization of the composition. Examples for suitable bactericides are those based on dichlorophene and benzylalcohol hemi formal (Proxel® from ICI or Acticide® RS from Thor Chemie and Kathon® MK from Rohm & Haas) and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
[0611] Examples for anti-foaming agents are silicone emulsions (such as e g. Silikon® SRE, Wacker, Germany or Rhodorsil®, Rhodia, France), long chain alcohols, fatty acids, salts of fatty acids, fluoroorganic compounds and mixtures thereof.
[0612] Suitable colorants are pigments of low water solubility and water-soluble dyes.
[0613] Examples to be mentioned under the designations rhodamine B, C. I., C. I. solvent red 1, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1, pigment blue 80, pigment yellow 1, pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48: 1, pigment red 57:1, pigment red 53:1, pigment orange 43, pigment orange 34, pigment orange 5, pigment green 3.
[0614] Example Formulation
[0615] Below is merely an example agricultural formulation that one skilled in the art could make with the formulation methods, the compounds and the carriers disclosed herein.
[0616] Suspensions formulation (either SC, OD, FS)
[0617] In an agitated ball mill, mix 20 parts by weight a mixture of the at least one additional fungicide and a compound of Formula I with 20 parts by weight, each, of block copolymer of ethylene oxide and propylene oxide (e.g. Pluronic® P-105) and alkylnaphthalene sulfonate condensate sodium salt (e.g. Morwet® D-425) dispersing / wetting agents. Further, 60 parts by weight of fatty acid alkylester organic solvent is added and vigorous mixing gives a suspension concentrate. Dilution with water provides a stable suspension of the formulation. The at least one additional fungicide and the compound of Formula I combined together is 40% by weight.5.3.5. Methods of use
[0618] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant. In one preferred aspect, the disclosure provides for a method wherein the plant is a com.
[0619] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the compositions of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant. In one preferred aspect, the disclosure provides for a method wherein the plant is a com.
[0620] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease (pathogen) is selected from: Anthracnose {Colletotrichum graminicola, Glomerella tucumanensis), Aspergillus ear and kernel rot {Aspergillus flavus), banded leaf and sheath spot {Rhizoctonia solani, Rhizoctonia microsclerotia), black bundle disease {Acremonium strictum, Cephalosporium acremonium), black kernel rot {Marasmiellus spp.), brown spot, black spot, stalk rot {Physoderma maydis), Cephalosporium kernel rot {Acremonium strictum, Cephalosporium acremonium), charcoal rot {Macrophomina phaseolina), Corticium ear rot {Thanatephorus cucumeris, Corticium sasakii), Curvularia leaf spot {Curvularia spp.), Didymella leaf spot {Didymella exitalis), Diplodia ear rot, stalk rot, leaf spot, leaf streak {Diplodia spp ), dry ear rot, cob, kernel and stalk rot {Nigrospora oryzae), ear rots {Alternaria spp., Aspergillus spp., Botrytis cinerea, Fusarium culmorum, Cunninghamella spp., Curvularia pallescens, Rhizopus spp., Gonatobotrys simplex, Doratomyces stemonitis, Cephalotrichum stemonitis, Pithomyces maydicus, Scopulariopsis brumptii), ergot {Claviceps gigantea), eyespot {Aureobasidium zeae, Kabatiella zeae), Fusarium kernel, root and stalk rot, seed rot, stalk rot, ear rot, and seedling blight {Fusarium spp., Gibberella spp.), gray ear rot {Botryosphaeria zeae, Physalospora zeae), gray leaf spot, Cercospora leaf spot {Cercospora sorghi, Cercospora zeae-maydis), Helminthosporium root rot {Exserohilum pedicellatum, Helminthosporium pedicellatum), Cladosporium rot {Cladosporium spp.), leaf spots {Alternaria alternata, Ascochyta maydis, Ascochyta tritici, Ascochyta zeicola, Bipolaris victoriae, Helminthosporium victoriae, Cochliobolus victoriae, Cochliobolus sativus, Bipolaris sorokiniana, Epicoccum nigrum, Exserohilum prolatum, Drechslera prolata, Graphium penicillioides, Leptosphaeria maydis, Leptothyrium zeae, Ophiosphaerella herpotricha, Paraphaeosphaeria michotii, Phoma spp., Septaria spp.), Northern corn leaf blight {Setosphaeria turcica, white blast, stalk rot, stripe {Exserohilum turcicum, Helminthosporium turcicum), Northern corn leaf spot {Cochliobolus carbonum), Helminthosporium ear rot {Bipolaris zeicola, Helminthosporium carbonum), Penicillium ear rot, blue eye, blue mold {Pennicillium spp.), Phaeocytostroma stalk rot and root rot {Phaeocytostroma ambiguum,Phaeocytosporella zeae), Phaeosphaeria leaf spot {Phaeosphaeria maydis, Sphaerulina maydis), Physalospora ear rot, Botryosphaeria ear rot {Botryosphaeria festucae, Physalospora zeicola), Pyrenochaeta stalk rot and root rot {Phoma terrestris, Pyrenochaeta terrestris), red kernel disease, ear mold, leaf and seed rot {Epicoccum nigrum), Rhizoctonia ear rot, root rot, stalk rot {Rhizoctonia spp.), root rots {Alternaria alternata, Cercospora sorghi, Dictochaeta fertilis, Fusarium spp., Gibberella spp., Microdochium bolleyi, Mucor spp., Periconia circinata, Rhizopus arrhizus) Rostratum leaf spot, Helminthosporium leaf disease, ear and stalk rot {Setosphaeria rostrata, Helminthosporium rostratum, rusts {Puccinia spp., Physopella spp.), brown rust of corn {Puccinia polysora), Sclerotium ear rot, Southern blight Sclerotium rolfsii), seed rot-seedling blight {Bipolaris spp., Helminthosporium spp., Diplodia maydis, Exserohilum spp., Fusarium spp., Gibberella spp., Macrophomina phaseolina, Penicillium spp., Phomopsis spp., Rhizoctonia spp., Sclerotium rolfsii, Spicaria spp.), Selenophoma leaf spot (Selenophoma sp.), sheath rot (Gaeumannomyces graminis), shuck rot (Myrothecium gramineum), silage mold Monascus spp.), smuts {Ustilago spp., Ustilaginoidea virens, Sphacelotheca reiliana, Sporisorium holci-sorghi), Southern corn leaf blight and stalk rot {Cochliobolus heterostrophus, Bipolaris maydis, Helminthosporium maydis), stalk rots (Cercospora sorghi, Fusarium spp., Nectria haematococca, Mariannaea elegans, Mucor spp., Rhopographus zeae, Spicaria spp.), storage rots {Aspergillus spp., Penicillium spp.), tar spot {Phyllachora maydis, Monographella maydis, Coniothyrium phyllachorae), Trichoderma ear rot and root rot {Trichoderma viride, Trichoderma lignorum, Hypocrea spp.), white ear rot, root and stalk rot {Stenocarpella maydis, Diplodia zeae), yellow leaf blight (Ascochyta ischaemi, Phyllosticta maydis, Mycosphaerella zeae-maydis) and Zonate leaf spot {Gloeocercospora sorghi.
[0621] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease (pathogen) is selected from tar spot {Phyllachora maydis), grey leaf spot {Cercospora zeae-maydis), northern corn leaf blight {Exserohilum turcicum), common rust {Puccinia sorghi), southern rust {Puccinia polysora), common smut {Ustilago maydis), Fusarium ear and stalk rot {Fusarium verticillioides), anthracnose leaf blight(Colletotrichum graminicola), yellow leaf blight (Phyllosticta), eyespot (Kabatiella zeae), southern com leaf blight Bipolaris maydis). Helminthosporium leaf spot and ear rot (Bipolaris, Drechslera, or Exserohilum), charcoal stalk rot (Macrophomina phaseo na), Gibberella stalk and ear rot Gibberella zeae), Diplodia stalk and ear rot (Stenocarpella maydis), anthracnose stalk rot Colletotrichum graminicola), Aspergillus ear rot (Aspergillus flaws), storage mold (Aspergillus or Penicillium).
[0622] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease (pathogen) is selected from grey leaf spot (Cercospora zeae-maydis), northern corn leaf blight (Exserohilum turcicum), southern rust (Puccini a polysora), common smut (Ustilago maydis) and Fusarium ear and stalk rot (Fusarium verticillioides).
[0623] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease is selected from: Anthracnose, Aspergillus ear and kernel rot, banded leaf and sheath spot, black bundle disease, black kernel rot, brown spot, black spot, stalk rot, Cephalosporium kernel rot, charcoal rot, Corticium ear rot, Curvularia leaf spot, Didymella leaf spot, Diplodia ear rot, stalk rot, leaf spot, leaf streak, dry ear rot, cob, kernel and stalk rot, ear rots, ergot, eyespot, Fusarium kernel, root and stalk rot, seed rot, stalk rot, ear rot, and seedling blight, gray ear rot, gray leaf spot, Cercospora leaf spot, Helminthosporium root rot, Cladosporium rot, leaf spots, Northern corn leaf blight, white blast, stalk rot, stripe, Northern corn leaf spot, Helminthosporium ear rot, Penicillium ear rot, blue eye, blue mold, Phaeocytostroma stalk rot and root rot, Phaeosphaeria leaf spot, Physalospora ear rot, Botryosphaeria ear rot, Pyrenochaeta stalk rot and root rot, red kernel disease, ear mold, leaf and seed rot, Rhizoctonia ear rot, root rot, stalk rot, root rots Rostratum leaf spot, Helminthosporium leaf disease, ear and stalk rot, rusts, brown rust of corn, Sclerotium ear rot, Southern blight, seed rot-seedling blight, Selenophoma leaf spot, sheath rot, shuck rot, silage mold, smuts, Southerncorn leaf blight and stalk rot, stalk rots, storage rots, tar spot, Trichoderma ear rot and root rot, white ear rot, root and stalk rot, yellow leaf blight and Zonate leaf spot.
[0624] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease is selected from: tar spot, grey leaf spot, northern corn leaf blight, common rust, southern rust, common smut, Fusarium ear and stalk rot, anthracnose leaf blight, yellow leaf blight, eyespot, southern com leaf blight, Helminthosporium leaf spot and ear rot, charcoal stalk rot, Gibberella stalk and ear rot, Diplodia stalk and ear rot, anthracnose stalk rot, Aspergillus ear rot and storage mold.
[0625] In one aspect, the disclosure provides for a method of treating a plant for the control of a fungal pathogen, wherein any one of the mixtures or compositions thereof of any one of the previous aspects is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant wherein the disease is selected from grey leaf spot, northern corn leaf blight, southern rust, common smut and Fusarium ear and stalk rot.
[0626] In one preferred aspect, the disclosure provides for a method of treating a plant of corn, comprising the application of any one of the mixtures or compositions of any one of the previous aspects to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant, for control of an undesirable fungal pathogen selected from the group consisting of Colletotrichum graminicola, Glomerella tucumanensis, Aspergillus flavus, Rhizoctonia solani, Rhizoctonia microsclerotia, Acremonium strictum, Cephalosporium acremonium, Marasmiellus spp., Physoderma maydis, Acremonium strictum, Cephalosporium acremonium, Macrophomina phaseolina, Thanatephorus cucumeris, Corticium sasakii, Curvularia spp., Didymella exitalis, Diplodia spp., Nigrospora oryzae, Alternaria spp., Aspergillus spp., Botrytis cinerea, Fusarium culmorum, Cunninghamella spp., Curvularia pallescens, Rhizopus spp., Gonatobotrys simplex, Doratomyces stemonitis, Cephalotrichum stemonitis, Pithomyces maydicus, Scopulariopsis brumptii, Claviceps gigantea, Aureobasidium zeae, Kabatiella zeae, Fusarium spp., Gibberella spp., Botryosphaeria zeae, Physalospora zeae, Cercospora sorghi, Cercospora zeae-maydis, Exserohilum pedicellatum, Helminthosporium pedicellatum, Cladosporium spp., Alternariaalternata, Ascochyta maydis, Ascochyta tritici, Ascochyta zeicola, Bipolaris victoriae, Helminthosporium victoriae, Cochliobolus victoriae, Cochliobolus salivas, Bipolaris sorokiniana, Epicoccum nigrum, Exserohilum prolatum, Drechslera prolata, Graphium penicillioides, Leptosphaeria maydis, Leptothyrium zeae, Ophiosphaerella herpotricha, Paraphaeosphaeria michotii, Phoma spp., Septoria spp., Setosphaeria turcica, Exserohilum turcicum, Helminthosporium turcicum, Cochliobolus carbonum, Bipolaris zeicola, Helminthosporium carbonum, Pennicillium spp., Phaeocytostroma ambiguum, Phaeocytosporella zeae, Phaeosphaeria maydis, Sphaerulina maydis, Botryosphaeria festucae, Physalospora zeicola, Phoma terrestris, Pyrenochaeta terrestris, Epicoccum nigrum, Rhizoctonia spp., Alternaria alternata, Cercospora sorghi, Dictochaeta fertilis, Fusarium spp., Gibberella spp., Microdochium bolleyi, Mucor spp., Periconia circinata, Rhizopus arrhizus Setosphaeria rostrata, Helminthosporium rostratum, Puccinia spp., Physopella spp., Puccinia polysora, Sclerotium rolfsii, Bipolaris spp., Helminthosporium spp., Diplodia maydis, Exserohilum spp., Fusarium spp., Gibberella spp., Macrophomina phaseolina, Penicillium spp., Phomopsis spp., Rhizoctonia spp., Sclerotium rolfsii, Spicaria spp., Selenophoma sp., Gaeumannomyces graminis, Myrothecium gramineum, Monascus spp., Ustilago spp., Ustilaginoidea virens, Sphacelotheca reiliana, Sporisorium holci-sorghi, Cochliobolus heterostrophus, Bipolaris maydis, Helminthosporium maydis, Cercospora sorghi, Fusarium spp., Nectria haematococca, Mariannaea elegans, Mucor spp., Rhopographus zeae, Spicaria spp., Aspergillus spp., Penicillium spp., Phyllachora maydis, Monographella maydis, Coniothyrium phyllachorae, Trichodermaviride, Trichoderma lignorum, Hypocrea spp., Stenocarpella maydis, Diplodia zeae, Ascochyta ischaemi, Phyllosticta maydis, Mycosphaerella zeae-maydis and Gloeocercospora sorghi, and any combinations thereof.
[0627] In one preferred aspect, the disclosure provides for a method of treating a plant of corn, comprising the application of any one of the mixtures or compositions of any one of the previous aspects to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant, for control of an undesirable fungal pathogen selected from the group consisting of Puccinia sp. (PUCCSP), Ustilago maydis (USTIMA), Exserohilum turcicum (SETOTU), Phyllachora maydis (PHYRMA), Cercospora zeae-maydis (CERCZM), Puccinia polysora(PUCCPY), Puccinia polysora, Fusarium verticillioides (FUSAVR), Colletotrichum graminicola, Phyllosticta maydis, Aureobasidium zeae, Helminthosporium maydis, Helminthosporium carbonum, Ma...
Claims
CLAIMSWhat is claimed:
1. A fungicidal mixture comprising:a) a fungicidally effective amount of the Compound of Formula I:(Compound I)and / or salts, solvates, or hydrates thereof;b) at least one additional fungicide selected from sterol biosynthesis inhibitor (SBI), succinate dehydrogenase inhibitor of complex II (SDHI), quinone outside inhibitor of complex III (MET III Qo), quinone inside inhibitor of complex III (MET III Qi), uncouplers of oxidative oxidative phosphorylation, signal transduction inhibitor with unknown mechanism (FRAC Group El), host plant defense induction salicylate related inhibitor (FRAC Group P01), actin / myosin / fimbrin function inhibitor, adenosine deaminase inhibitor, methionine biosynthesis inhibitor, MAP / histidine kinase inhibitor, dihydroorotate dehydrogenase inhibitor, tubulin dynamics modulator, chemical multi-site inhibitor, unknown mode of action fungicide, newly developed fungicides, and combinations thereof.
2. The mixture of claim 1, wherein the at least one additional fungicide is selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bifemetstrobin, bixafen, boscalid, bupirimate, chlorothalonil, copper oxychloride, cyflufenamid, cyproconazole, cyprodinil, Compound XI (also known as cyprometoxazam), difenoconazole, epoxiconazole, famoxadone, fenbuconazole, feneptamidoquin, fenpicoxamid, fenpropidin, fenpropimorph, florylpicoxamid, fluazinam, fludioxonil, flufenoxadiazam, fluindapyr, fl umetyl sulforim, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, fluoxytioconazole, folpet, inpyrfluxam, ipflufenoquin, isofetamid, isoflucypram, mancozeb, mefentrifluconazole,metarylpicoxamid, metconazole, Compound X6 (also known as metcyclofenstrobin), metominostrobin, metrafenone, metyltetraprole, myclobutanil, penconazole, penthiopyrad, picoxystrobin, propiconazole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin, pyrapropoyne, pyraziflumid, pyridachlometyl, pyriofenone, quinofumelin, quinoxyfen, spiroxamine, calcium polysulfide, tebuconazole, tetraconazole, trifloxystrobin, and mixtures thereof.
3. The mixture of claim 1, wherein the at least one additional fungicide is selected from the group consisting of azoxystrobin, benzovindiflupyr, bixafen, cyproconazole, florylpicoxamid, fluindapyr, fluopyram, flutriafol, fluxapyroxad, fluoxastrobin, mefentrifluconazole, metconazole, penthiopyrad, picoxystrobin, propiconazole, prothioconazole, pydiflumetofen, pyraclostrobin, tebuconazole, tetraconazole, trifloxystrobin, difenoconazole, flufenoxidiazam, folpet, fenpicoxamid, inpyrfluxam, isoflucypram, metyltetraprole, proquinazid, and mixtures thereof4. The mixture of any one of claims 1-3, wherein the mixture comprises Compound I and one additional fungicide compound.
5. The mixture of any one of claims 1-3, wherein the mixture comprises Compound I and two additional fungicide compounds.
6. The mixture of claim 5, wherein the two additional fungicide compounds are picoxystrobin and azoxystrobin, picoxystrobin and benzovindiflupyr, picoxystrobin and cyproconazole, picoxystrobin and difenoconazole, picoxystrobin and florylpicoxamid, picoxystrobin and fluindapyr, picoxystrobin and fluopyram, picoxystrobin and flutriafol, picoxystrobin and fluxapyroxad, picoxystrobin and inpyrfluxam, picoxystrobin and isoflucypram, picoxystrobin and mefentrifluconazole, picoxystrobin and metarylpicoxamid, picoxystrobin and metominostrobin, picoxystrobin and metyltetraprole, picoxystrobin and propiconazole, picoxystrobin and prothioconazole, picoxystrobin and pyraclostrobin, picoxystrobin and tebuconazole, picoxystrobin and tetraconazole, picoxystrobin and trifloxystrobin, fluxapyroxad and azoxystrobin, fluxapyroxad and cyproconazole, fluxapyroxad and difenoconazole, fluxapyroxad and florylpicoxamid, fluxapyroxad and fluindapyr, fluxapyroxad and fluopyram,fluxapyroxad and flutriafol, fluxapyroxad and inpyrfluxam, fluxapyroxad and isoflucypram, fluxapyroxad and mefentrifluconazole, fluxapyroxad and metarylpicoxamid, fluxapyroxad and metominostrobin, fluxapyroxad and metyltetraprole, fluxapyroxad and propiconazole, fluxapyroxad and prothioconazole, fluxapyroxad and pyraclostrobin, fluxapyroxad and tebuconazole, fluxapyroxad and tetraconazole, fluxapyroxad and trifloxystrobin, pydiflumetofen and azoxystrobin, pydiflumetofen and benzovindiflupyr, pydiflumetofen and cy proconazole, pydiflumetofen and difenoconazole, pydiflumetofen and florylpicoxamid, pydiflumetofen and fluindapyr, pydiflumetofen and fluopyram, pydiflumetofen and flutriafol, pydiflumetofen and fluxapyroxad, pydiflumetofen and inpyrfluxam, pydiflumetofen and isoflucypram, pydiflumetofen and mefentrifluconazole, pydiflumetofen and metarylpicoxamid, pydiflumetofen and metominostrobin, pydiflumetofen and metyltetraprole, pydiflumetofen and picoxystrobin, pydiflumetofen and propiconazole, pydiflumetofen and prothioconazole, pydiflumetofen and pyraclostrobin, pydiflumetofen and tebuconazole, pydiflumetofen and tetraconazole, pydiflumetofen and trifloxystrobin, flutriafol and azoxystrobin, flutriafol and benzovindiflupyr, flutriafol and cyproconazole, flutriafol and difenoconazole, flutriafol and florylpicoxamid, flutriafol and fluindapyr, flutriafol and fluopyram, flutriafol and inpyrfluxam, flutriafol and isoflucypram, flutriafol and mefentrifluconazole, flutriafol and metarylpicoxamid, flutriafol and metominostrobin, flutriafol and metyltetraprole, flutriafol and propiconazole, flutriafol and prothioconazole, flutriafol and pyraclostrobin, flutriafol and tebuconazole, flutriafol and tetraconazole, or flutriafol and trifloxystrobin.
7. The mixture of any one of claims 1-6, wherein the mixture provides control or prevention of a disease selected from the group consisting of Anthracnose, Aspergillus ear and kernel rot, banded leaf and sheath spot, black bundle disease, black kernel rot, brown spot, black spot, stalk rot, Cephalosporium kernel rot, charcoal rot, Corticium ear rot, Curvularia leaf spot, Didymella leaf spot, Diplodia ear rot, stalk rot, leaf spot, leaf streak, dry ear rot, cob, kernel and stalk rot, ear rots, ergot, eyespot, Fusarium kernel, root and stalk rot, seed rot, stalk rot, ear rot, and seedling blight, gray ear rot, gray leaf spot,Cercospora leaf spot, Helminthosporium root rot, Cladosporium rot, leaf spots, Northern corn leaf blight, white blast, stalk rot, stripe, Northern corn leaf spot, Helminthosporium ear rot, Penicillium ear rot, blue eye, blue mold, Phaeocytostroma stalk rot and root rot, Phaeosphaeria leaf spot, Physalospora ear rot, Botryosphaeria ear rot, Pyrenochaeta stalk rot and root rot, red kernel disease, ear mold, leaf and seed rot, Rhizoctonia ear rot, root rot, stalk rot, root rots Rostratum leaf spot, Helminthosporium leaf disease, ear and stalk rot, rusts, brown rust of corn, Sclerotium ear rot, Southern blight, seed rot-seedling blight, Selenophoma leaf spot, sheath rot, shuck rot, silage mold, smuts, Southern corn leaf blight and stalk rot, stalk rots, storage rots, tar spot, Trichoderma ear rot and root rot, white ear rot, root and stalk rot, yellow leaf blight, Zonate leaf spot, and any combinations thereof.
8. The mixture of any one of claims 1-6, wherein the mixture provides control of a fungal pathogen, and the pathogen is selected from the group consisting of Puccinia sp.(PUCCSP), Ustilago maydis (USTIMA), Exserohilum turcicum (SETOTU), Phyllachora maydis (PHYRMA), Cercospora zeae-maydis (CERCZM), Puccinia polysora (PUCCPY), Puccinia polysora, Fusarium verticillioides (FUSAVR), Colletotrichum graminicola, Phyllosticta maydis, Aureobasidium zeae, Helminthosporium maydis, Helminthosporium carbonum, Macrophomina phaseolina, Gibberella zea, Diplodia maydis, Colletotrichum graminicola, Aspergillus spp.
9. A fungicidal composition comprising a fungicidally effective amount of any one of the mixtures of Claims 1-6 and an agriculturally acceptable carrier.
10. Use of the compound of Formula IFormula Ior an acceptable salt, solvate, or hydrate thereof for control of a fungal pathogen and / or a disease in corn.
11. Use of the mixture of any one of claims 1-6 or the composition of claim 9 for control of a fungal pathogen and / or a disease in corn.
12. The use of any one of claims 10 and 11, wherein the disease is selected from the group consisting of Anthracnose, Aspergillus ear and kernel rot, banded leaf and sheath spot, black bundle disease, black kernel rot, brown spot, black spot, stalk rot, Cephalosporium kernel rot, charcoal rot, Corticium ear rot, Curvularia leaf spot, Didymella leaf spot, Diplodia ear rot, stalk rot, leaf spot, leaf streak, dry ear rot, cob, kernel and stalk rot, ear rots, ergot, eyespot, Fusarium kernel, root and stalk rot, seed rot, stalk rot, ear rot, and seedling blight, gray ear rot, gray leaf spot, Cercospora leaf spot, Helminthosporium root rot, Cladosporium rot, leaf spots, Northern corn leaf blight, white blast, stalk rot, stripe, Northern corn leaf spot, Helminthosporium ear rot, Penicillium ear rot, blue eye, blue mold, Phaeocytostroma stalk rot and root rot, Phaeosphaeria leaf spot, Physalospora ear rot, Botryosphaeria ear rot, Pyrenochaeta stalk rot and root rot, red kernel disease, ear mold, leaf and seed rot, Rhizoctonia ear rot, root rot, stalk rot, root rots Rostratum leaf spot, Helminthosporium leaf disease, ear and stalk rot, rusts, brown rust of corn, Sclerotium ear rot, Southern blight, seed rot-seedling blight, Selenophoma leaf spot, sheath rot, shuck rot, silage mold, smuts, Southern corn leaf blight and stalk rot, stalk rots, storage rots, tar spot, Trichoderma ear rot and root rot, white ear rot, root and stalk rot, yellow leaf blight and Zonate leaf spot.
13. The use of any one of claims 10 and 11, wherein the pathogen is selected from the group consisting of Puccinia sp. (PUCCSP), Ustilago maydis (USTIMA), Exserohilum turcicum (SETOTU), Phyllachora maydis (PHYRMA), Cercospora zeae-maydis (CERCZM), Puccinia polysora (PUCCPY), Puccinia polysora, Fusarium verticillioides (FUSAVR), Colletotrichum graminicola, Phyllosticta maydis, Aureobasidium zeae, Helminthosporium maydis, Helminthosporium carbonum, Macrophomina phaseolina, Gibberella zea, Diplodia maydis, Colletotrichum graminicola, Aspergillus spp.
14. A method for control of fungal pathogen in corn, wherein the compound of Formula I or a salt, solvate, or hydrate thereof is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant.
15. A method for control of fungal pathogen in corn, wherein the mixture of any one of claims 1-6 or the composition of claim 9 is applied to one of the plant, foliage of the plant, a plant seed, and an area adjacent to the plant.