Composition for preventing or treating allergic diseases comprising SOCS3 inhibitor as active ingredient
The use of SOCS3 inhibitors in a pharmaceutical composition addresses the side effects and recurrence issues of existing therapies by regulating the JAK-STAT pathway, effectively suppressing immune responses and reducing allergic reactions.
WO2026111036A1PCT designated stage Publication Date: 2026-05-28KOREA UNIV RES & BUSINESS FOUND
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- KOREA UNIV RES & BUSINESS FOUND
- Filing Date
- 2025-02-13
- Publication Date
- 2026-05-28
Smart Images
Figure KR2025002128_28052026_PF_FP_ABST
Abstract
The present invention relates to: a compound for inhibiting SOCS3 activity; a pharmaceutical composition for treating allergic diseases, comprising same as an active ingredient; and the like. More specifically, compounds capable of binding were derived from a drug database through AI-based SOCS3 binding site simulation, and it has been confirmed that these compounds actually inhibit SOCS3 and increase JAK2 kinase activity and the degree of STAT3 phosphorylation, and thus can be used for preventing or treating allergic diseases.
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