A derivative of compound bixanthene and bi(cyclopenta[ b]chromene)

A novel synthesis process for Bixanthene and Bi(cyclopenta[Z?]chromene compounds using hydroxybenzaldehydes and cycloalkanones with secondary amines and acids, and carbodiimides, simplifies the production of these compounds, improving their structural and reactivity profiles.

WO2026115580A1PCT designated stage Publication Date: 2026-06-04DESAI ARPITA +2
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
DESAI ARPITA
Filing Date
2025-11-28
Publication Date
2026-06-04

AI Technical Summary

Technical Problem

Existing synthetic routes for cyclopenta[c] chromene compounds are complex, require noble metals or alkalis, and yield low results, limiting the production of these important bioactive compounds.

Method used

A novel synthesis process involving the reaction of hydroxybenzaldehydes and cycloalkanones with secondary amines and acids, followed by carbodiimides and peptide coupling reagents, in specific solvents, to form a six-membered ring structure in Bixanthene and Bi(cyclopenta[Z?]chromene derivatives.

Benefits of technology

This process simplifies the synthesis of Bixanthene and Bi(cyclopenta[Z?]chromene compounds, enhancing their electronic delocalization and steric configuration, optimizing structural integrity and reactivity, and facilitating the formation of unique interplay of electronic interactions and steric effects.

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Abstract

The present invention relates to a Derivative Compound of Bixanthene and Bi(cyclopenta[b]chromene) of formula I. More particularly, the present invention relates to a process for preparation of a Derivative Compound of Bixanthene and Bi(cyclopenta[b]chromene) of formula I. Further, the present invention relates to Derivative Compound of Bixanthene and Bi(cyclopenta[b]chromene) with potent anti-cancer activity as pharmaceutical agents and their pharmaceutically acceptable salts and their pharmaceutically acceptable solvents or mixture thereof.a derivative of compound bixanthene and bi(cyclopenta[ b]chromene)
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