Biosensor and system for measuring concentration of glucose in saliva
The biosensor system for saliva-based glucose measurement addresses skin damage and discomfort by using a voltage-controlled biosensor with a reagent layer to accurately measure glucose concentration, minimizing anion interference.
WO2026116756A1PCT designated stage Publication Date: 2026-06-04DONG WOON ANATECH CO LTD
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- DONG WOON ANATECH CO LTD
- Filing Date
- 2025-10-14
- Publication Date
- 2026-06-04
AI Technical Summary
Technical Problem
Existing self-diagnosis testing methods using blood samples cause skin damage, increase infection risk, and induce pain and fear, prompting a need for non-invasive alternatives like saliva-based testing that minimizes interference from anions.
Method used
A biosensor system for measuring glucose in saliva using a saliva glucose measuring device with a reagent layer containing glucose dehydrogenase and an electron transfer agent, applying a voltage of 150mV to 300mV to minimize anion interference and accurately measure glucose concentration.
Benefits of technology
The system effectively suppresses anion attraction, allowing precise glucose concentration measurement in saliva, thereby predicting blood glucose levels without skin damage or discomfort.
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Smart Images
Figure KR2025016111_04062026_PF_FP_ABST
Abstract
The present invention provides a biosensor for detecting glucose in saliva by using a saliva glucose measurement device, the biosensor comprising: an electrically insulated substrate; a plurality of electrodes disposed on the substrate and including a working electrode and a reference electrode for detecting glucose in the saliva; and a reagent layer disposed on the plurality of electrodes, wherein the reagent layer is disposed in a saliva inflow path which is located in the biosensor and configured to allow the saliva to flow thereinto. The reagent layer includes glucose dehydrogenase (GDH) and an electron transfer mediator, the saliva glucose measurement device is configured to apply a voltage to the working electrode and the reference electrode, the working electrode and the reference electrode are configured to transmit, to the saliva glucose measurement device, a current signal generated due to an oxidation / reduction reaction between the glucose dehydrogenase and the glucose in the saliva according to the applied voltage, and the value of the applied voltage is included in a numerical range of 150 mV to 300 mV.
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