Application device and analyte monitoring system

Abstract

Provided are an application device and an analyte monitoring system. The application device is an application device configured to apply a monitoring device to a host. The monitoring device comprises an on-body unit and a sensor. The application device comprises a housing, an auxiliary mechanism releasably retained in the housing, and a driving mechanism. The application device further comprises a first trigger mechanism arranged in a travel path of the auxiliary mechanism. The auxiliary mechanism, after being released by the housing, moves toward the proximal end under the action of the driving mechanism, and in the process of the auxiliary mechanism moving toward the proximal end, the first trigger mechanism enables an engagement part to move relative to the on-body unit, so that the engagement part does not protrude from the bottom of the on-body unit. In this way, an application device and an analyte monitoring system that are highly reliable and easy for a user to use can be provided.

Description

Application device and analyte monitoring system Technical Field

[0001] This disclosure relates to the biomedical engineering industry, specifically to an application device and an analyte monitoring system. Background Technology

[0002] For clinical diagnosis or personal health monitoring, continuous monitoring of physiological parameters in a user's body is frequently required. For example, for diabetic patients, it is essential to monitor glucose levels in real-time and continuously on a daily basis so that glucose levels can be regulated promptly through methods such as dietary adjustments or medication, thereby reducing the occurrence of complications caused by abnormal glucose levels. Currently, continuous monitoring devices (such as continuous glucose monitoring systems (CGM)) are commonly used to continuously monitor glucose levels in the body.

[0003] Continuous monitoring devices typically include a sensor and an on-body unit electrically connected to the sensor. Generally, an implantation device, including an implantation needle, is used to guide the sensor subcutaneously into the host to monitor analytes. The on-body unit then receives and transmits the analyte signals sensed by the sensor. Because the sensor needs to be implanted subcutaneously, the implanted portion of the sensor and the tip of the implantation needle usually need to be sterilized and sealed before leaving the factory to minimize the impact of bacteria or foreign objects on the host's health. Currently, a novel sterilization and sealing structure relies on the locking action of a needle shank extending from the bottom of the on-body unit with a sterilization cap to seal the internal sensor and sharp objects.

[0004] However, if the needle handle is still protruding from the bottom of the protruding unit when the implantation assist device pushes the continuous monitoring device to the host, it may lead to incomplete push and increased pain for the user. If the needle handle retraction is designed to occur before pushing the continuous monitoring device, it usually requires additional operation by the user before the implantation action, or the addition of complex mechanical linkage structures to the implantation assist device. This design not only increases the structural complexity and manufacturing cost of the implantation assist device, but also may introduce the risk of retraction failure due to tolerances between components, wear, or improper user operation. It may also cause user confusion, making it unclear whether the retraction has been successful or whether the application stage has been reached. If retraction fails, the protruding mating components may come into contact with the user's skin during subsequent application, causing discomfort or even injury. Summary of the Invention

[0005] This disclosure is made in view of the above-mentioned state of the prior art, and its purpose is to provide a highly reliable application device and analyte monitoring system that is easy for users to use.

[0006] Therefore, a first aspect of this disclosure provides an application device for applying a monitoring device to a host, the monitoring device including a body unit and a sensor, the application device including a housing, an auxiliary mechanism releasably held in the housing, and a drive mechanism, the auxiliary mechanism including a moving body for accommodating the monitoring device and a puncture member, the housing having a proximal end that is close to the host during operation and a distal end that is far from the host, the puncture member including an engagement portion extending from the bottom of the body unit in a standby state, and the puncture member configured to place the sensor at least partially under the skin of the host, the drive mechanism applying force to the auxiliary mechanism toward the proximal end, the application device including a first triggering mechanism disposed on the travel path of the auxiliary mechanism, the auxiliary mechanism moving toward the proximal end under the action of the drive mechanism after being released by the housing, the first triggering mechanism causing the engagement portion to move relative to the body unit so that the engagement portion does not protrude from the bottom of the body unit.

[0007] In the application device of this disclosure, a first triggering mechanism disposed on the travel path of the auxiliary mechanism enables the joint protruding from the bottom of the body unit to move relative to the body unit as the auxiliary mechanism approaches its proximal end, achieving a posture where the joint no longer protrudes from the bottom of the body unit. That is, this disclosure integrates the action of retracting the joint into the process of the drive mechanism pushing the auxiliary mechanism, automating the process. This design eliminates the need for the user to perform an additional operation of retracting the joint before applying the monitoring device to the host, simplifying user operation and eliminating the need for complex linkage structures, thus reducing the risk of mechanical failure and improving the reliability and safety of the application device. Therefore, according to this disclosure, a user-friendly and highly reliable application device can be provided.

[0008] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the bottom of the joint does not protrude from the proximal end of the housing during the entire application process of the auxiliary mechanism. This reduces the likelihood of the joint coming into contact with the host's skin during application.

[0009] Additionally, in the application device according to the first aspect of this disclosure, optionally, the first triggering mechanism is triggered when the bottom of the joint moves to the proximal end of the housing or before the bottom of the joint moves to the proximal end of the housing. This allows the joint to be easily retracted to a position that does not protrude from the bottom of the body unit before it comes into contact with the host's skin.

[0010] Additionally, in the application device according to the first aspect of this disclosure, optionally, the puncture member is releasably held in the moving body, and the first triggering mechanism is disposed on the travel path of the puncture member, causing the moving body to release the puncture member as the moving body and the puncture member approach the proximal end together. In this case, releasing the puncture member by the moving body through the first triggering mechanism facilitates relative movement between the joint and the upper body unit so that the joint does not protrude from the bottom of the upper body unit.

[0011] Additionally, in the application device according to the first aspect of this disclosure, optionally, before the oncounit is applied to the host, the puncture member is released in advance so that the puncture member assists in placing the sensor at least partially under the host's skin in an orientation where the engagement does not protrude from the bottom of the oncounit. In this case, it is convenient to retract the engagement to a position where it does not protrude from the bottom of the oncounit before the engagement contacts the host's skin, without affecting the sharp object's assistance in inserting the sensor into the host's subcutaneous tissue.

[0012] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the moving body includes a holding portion, and the puncture member includes a locking portion that is releasably interlocked with the holding portion. This allows the puncture member to be releasably disposed on the moving body through the cooperation of the holding portion and the locking portion.

[0013] Additionally, in the application device according to the first aspect of this disclosure, the application device may optionally include a second drive mechanism. The second drive mechanism applies force to the puncture member toward the distal end. When the puncture member is released by the moving body, the puncture member moves toward the distal end under the action of the second drive mechanism. In this case, the second drive mechanism enables the joint to move toward the distal end to a position that does not protrude from the bottom of the body unit after the puncture member is released. Furthermore, it facilitates automatic needle return after the puncture member assists in implanting the sensor subcutaneously into the host.

[0014] Additionally, in the application device according to the first aspect of this disclosure, optionally, the moving body holds the puncture member in segments. The application device further includes a second triggering mechanism disposed on the travel path of the puncture member. The first triggering mechanism causes the puncture member to be initially released by the moving body so that the joint does not protrude from the bottom of the body unit. The second triggering mechanism causes the puncture member to be released a second time by the moving body. The puncture member, released a second time, leaves the host under the action of the second driving mechanism. In this case, it is convenient to achieve segmented retraction of the puncture member during the pushing of the monitoring device. Compared to setting a separate triggering mechanism only at an appropriate position so that the puncture member simultaneously achieves the two purposes of joint retraction and leaving the host during a one-time retraction, this design of using the first triggering mechanism and the second triggering mechanism to achieve segmented retraction helps to ensure that the joint is retracted to a position that does not protrude from the bottom of the body unit before moving to the proximal end of the housing, and does not affect the puncture member's auxiliary implantation function of assisting in implanting the sensor under the host skin, thereby improving the reliability of the application device.

[0015] Additionally, in the application device according to the first aspect of this disclosure, optionally, the retaining portion has a first retaining surface and a second retaining surface facing the proximal end. In a standby state, the locking portion contacts and is restricted by the first retaining surface; after the first triggering mechanism is invoked, the locking portion separates from the first retaining surface, and under the action of the second driving mechanism, the puncture member moves to contact the second retaining surface and is restricted by the second retaining surface; after the second triggering mechanism is invoked, the locking portion separates from the second retaining surface, and the puncture member continues to move towards the distal end to leave the host under the action of the second driving mechanism. Thus, a retaining member with a simple structure can be provided, which helps to optimize the internal structural arrangement and overall miniaturization of the application device.

[0016] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the first triggering mechanism includes a protruding structure disposed on the travel path of the puncture member. This protruding structure of the first triggering mechanism is referred to as the first protruding structure. When the first triggering mechanism is invoked, the first protruding structure acts on the locking portion or the retaining portion, causing it to deform and separate the locking portion from the retaining portion. Thus, a triggering member with a simple structure can be provided, which helps to optimize the internal structural arrangement and overall miniaturization of the application device.

[0017] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the application device includes a second triggering mechanism disposed on the travel path of the puncture member. The second triggering mechanism includes a protruding structure disposed on the travel path of the puncture member. This protruding structure of the second triggering mechanism is referred to as the second protruding structure. When the second triggering mechanism is activated, the second protruding structure acts on the locking portion or the retaining portion, causing it to deform and separate the locking portion from the retaining portion. Thus, a triggering member with a simple structure can be provided, which helps to optimize the internal structural arrangement of the application device and to promote the overall miniaturization of the application device.

[0018] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the deformation of the locking portion or the retaining portion is smaller when the first protruding structure acts on the locking portion or the retaining portion compared to the second protruding structure. In this case, by using a design with different deformations through two triggers, it is convenient to arrange the two retaining surfaces of the retaining portion continuously, simplifying the structure of the retaining portion.

[0019] Furthermore, in the application device according to the first aspect of this disclosure, optionally, both the first protruding structure and the second protruding structure are formed on the inner wall of the housing and protrude toward the central axis of the application device. This provides two simple triggering structures, which helps optimize the internal structural arrangement and overall miniaturization of the application device. Moreover, in a scheme where the puncture member can automatically retract from the host's subcutaneous tissue, a single protruding structure can achieve one-time retraction. Based on this, only one additional protruding structure needs to be added to automatically and reliably achieve two-stage retraction of the puncture member during the application device's pushing process. That is, the reliability of the application device can be significantly improved with minimal design modifications.

[0020] Additionally, in the application device according to the first aspect of this disclosure, optionally, the end of the second protruding structure is closer to the central axis of the application device than the end of the first protruding structure.

[0021] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the first protruding structure and the second protruding structure are sequentially formed on the inner wall of the housing along a direction from the distal end to the proximal end. This facilitates the sequential two-stage retraction of the puncture member as it moves in the direction from the distal end to the proximal end.

[0022] Additionally, in the application device according to the first aspect of this disclosure, optionally, the moving body has a cutout generally along the central axis of the application device, the first retaining surface and the second retaining surface are arranged adjacent to the cutout, the first protruding structure and the second protruding structure protrude toward the central axis via the cutout, and the locking portion includes an arm extending generally along the central axis and a protrusion linked to the arm and protruding away from the central axis generally along a direction orthogonal to the central axis, the protrusion of the locking portion passing through the cutout to keep the piercing member in a held state. Thus, the locking portion can be held while maintaining a simplified structure.

[0023] Furthermore, in the application device according to the first aspect of this disclosure, optionally, when the first triggering mechanism is invoked, the arm of the locking portion is pressed towards the central axis by the first protruding structure, causing the protrusion of the locking portion to leave the first retaining surface to initially release the puncture member; when the second triggering mechanism is invoked, the arm of the locking portion is pressed towards the central axis by the second protruding structure, causing the protrusion of the locking portion to leave the second retaining surface to release the puncture member a second time. This facilitates a two-stage release of the puncture member.

[0024] Additionally, in the application device according to the first aspect of this disclosure, optionally, the puncture member includes a sharp object and a support seat releasably held in the moving body and supporting the sharp object, the engagement portion being formed on the sharp object and the locking portion being formed on the support seat.

[0025] Additionally, in the application device according to the first aspect of this disclosure, optionally, during the process of the auxiliary mechanism approaching the proximal end, the first triggering mechanism actuates the monitoring device to cause it to move relative to the joint and move a distance relative to the joint toward the proximal end so that the joint does not protrude from the bottom of the body unit.

[0026] Additionally, in the application device according to the first aspect of this disclosure, optionally, during the process of the auxiliary mechanism approaching the proximal end, the first triggering mechanism actuates the needle handle to cause it to move relative to the monitoring device and move a distance relative to the monitoring device toward the distal end so that the engagement portion does not protrude from the bottom of the body unit.

[0027] Additionally, in the application device according to the first aspect of this disclosure, the application device may optionally include a cap having an inner cavity, the cap being configured to couple with the engagement portion to form a sealed space accommodating at least a portion of the sensor, wherein when the cap is coupled with the engagement portion, the tail portion of the sensor is located within the sealed space. This facilitates the isolation of the sensor from external contamination in a standby state.

[0028] Additionally, in the application device according to the first aspect of this disclosure, optionally, the housing includes a holding portion, the moving body includes a locking portion releasably interlocked with the holding portion, and the application device includes a push triggering mechanism for triggering the housing to release the moving body. The push triggering mechanism includes a pressing portion and an actuating portion, wherein the holding of the moving body by the housing is released by applying an action to the pressing portion to cause the actuating portion to actuate the holding portion or the locking portion to separate the two.

[0029] Furthermore, in the application device according to the first aspect of this disclosure, optionally, the pressing part and the actuating part are integrally formed with the housing and disposed at the distal end of the housing. This simplifies the structural design of the push-triggered mechanism and improves its stability.

[0030] A second aspect of this disclosure provides an analyte monitoring system, including a monitoring device and an application device as described in the first aspect of this disclosure. The monitoring device includes an on-body unit and a sensor. The application device is used to apply the monitoring device to a host, wherein the sensor in the monitoring device applied to the host is at least partially located subcutaneously in the host for monitoring the analyte. In this second aspect of the disclosure, the analyte monitoring system includes an application device that is user-friendly and highly reliable, thereby providing a user-friendly and highly reliable analyte monitoring system.

[0031] According to this disclosure, an application device and an analyte monitoring system that are easy to use and highly reliable can be provided. Attached Figure Description

[0032] This disclosure will now be explained in further detail by way of example only with reference to the accompanying drawings.

[0033] Figure 1 is an overview diagram illustrating the application of the analyte monitoring system involved in this embodiment example.

[0034] Figure 2 is a schematic diagram showing a first-view view of the medical device involved in the example of this disclosure.

[0035] Figure 3 is a schematic diagram showing a second perspective of the medical device involved in the example of this disclosure.

[0036] Figure 4 is a block diagram illustrating the electronic device of the medical device according to the example of this disclosure.

[0037] Figure 5A is a first-view schematic diagram showing the overall appearance of the analyte monitoring system involved in the example of this disclosure.

[0038] Figure 5B is a first-view cross-sectional schematic diagram illustrating the analyte monitoring system according to the example of this disclosure.

[0039] Figure 5C is a first-view overall appearance schematic diagram showing another embodiment of the analyte monitoring system involved in the example of this disclosure.

[0040] Figure 5D is a cross-sectional schematic diagram showing the analyte monitoring system of Figure 5C as described in this disclosure example, along section line AA.

[0041] Figure 5E is a schematic diagram showing the cap and housing in Figure 5D after relative screwing, as described in the example of this disclosure.

[0042] Figure 6 is a schematic diagram of the overall appearance of the analyte monitoring system according to an example of this disclosure from a second perspective.

[0043] Figure 7A is a schematic diagram illustrating the first state of decoupling between the cap and the housing as described in the example of this disclosure.

[0044] Figure 7B is a schematic diagram illustrating a second state of decoupling between the cap and the housing as described in the example of this disclosure.

[0045] Figure 8A is a schematic diagram showing a first view of a first embodiment of the housing involved in the present disclosure.

[0046] Figure 8B is a schematic diagram showing a second view of a first embodiment of the housing involved in the present disclosure.

[0047] Figure 9A is a schematic diagram illustrating a second embodiment of the housing according to an example of this disclosure.

[0048] Figure 9B is a schematic diagram illustrating a third embodiment of the housing according to the examples of this disclosure.

[0049] Figure 10A is a schematic diagram showing a cap that mates with the housing of Figure 9A.

[0050] Figure 10B is a schematic diagram showing a cap that mates with the housing of Figure 9B.

[0051] Figure 11A is an exploded schematic diagram illustrating the analyte monitoring system according to an example of this disclosure.

[0052] Figure 11B is a structural schematic diagram from a first perspective illustrating another embodiment of the gasket involved in the example of this disclosure.

[0053] Figure 11C is a structural schematic diagram showing a second view of the gasket shown in Figure 11B, which is involved in the example of this disclosure.

[0054] Figure 12A is a perspective view showing the first housing involved in the example of this disclosure.

[0055] Figure 12B is a perspective view showing the first housing involved in the example of this disclosure from a second perspective.

[0056] Figure 12C is a schematic cross-sectional view illustrating the first housing involved in the example of this disclosure.

[0057] Figure 12D is a schematic diagram showing a first view of the first housing shown in Figure 5C, which is relevant to the example of this disclosure.

[0058] Figure 12E is a schematic diagram showing a second view of the first housing shown in Figure 5C, which is relevant to the example of this disclosure.

[0059] Figure 13 is an exploded schematic diagram showing the first housing, auxiliary mechanism, and first drive mechanism involved in the example of this disclosure.

[0060] Figure 14A is a schematic cross-sectional view showing the motion subject involved in the example of this disclosure being held.

[0061] Figure 14B is a schematic cross-sectional view showing the motion subject involved in the example of this disclosure when it is released.

[0062] Figure 15A is an exploded schematic diagram from a first perspective showing the second housing and auxiliary mechanism involved in the example of this disclosure.

[0063] Figure 15B is an exploded schematic diagram from a second perspective illustrating the second housing and auxiliary mechanisms involved in the example of this disclosure.

[0064] Figure 15C is an exploded schematic diagram from a third perspective showing the second housing and auxiliary mechanism involved in the example of this disclosure.

[0065] Figure 15D is a schematic diagram showing a first view of the second housing shown in Figure 5C, which is relevant to the example of this disclosure.

[0066] Figure 15E is a schematic diagram showing a second view of the second housing shown in Figure 5C, which is relevant to the example of this disclosure.

[0067] Figure 16A is an exploded schematic diagram from a first perspective showing the moving body, the second drive mechanism, and the puncture member involved in the example of this disclosure.

[0068] Figure 16B is an exploded schematic diagram from a second perspective showing the moving body, the second drive mechanism, and the puncture member involved in the example of this disclosure.

[0069] Figure 17A is a schematic cross-sectional view showing the puncture member being held according to the example of this disclosure.

[0070] Figure 17B is a schematic cross-sectional view showing the puncture member involved in the example of this disclosure being released.

[0071] Figure 18A is a first-view cross-sectional view showing the instrument kit involved in the example of this disclosure before the application of the medical device.

[0072] Figure 18B is a second-view cross-sectional view showing the instrument kit involved in the example of this disclosure before the application of the medical device.

[0073] Figure 18C is a cross-sectional view showing a first perspective of the instrument kit involved in the present disclosure being applied to a medical device.

[0074] Figure 18D is a cross-sectional view showing a second perspective of the instrument kit applied in a medical device according to an example of this disclosure.

[0075] Figure 18E is a cross-sectional view showing the medical device being applied to a host by the device kit according to the example of this disclosure.

[0076] Figure 18F is a cross-sectional view showing the puncture component of the instrument kit according to the example of this disclosure in a second state after the medical device has been applied.

[0077] Figure 18G is a cross-sectional view showing the puncture component of the instrument kit according to the example of this disclosure in the third state after the medical device has been applied.

[0078] Figure 19A is a cross-sectional view showing the moving body of the device kit according to the example of this disclosure locked again in the first retaining part after the medical device has been applied.

[0079] Figure 19B is a schematic diagram illustrating the second retaining part of another embodiment of the present disclosure.

[0080] Figure 19C is a schematic diagram illustrating the first and second protruding structures involved in the examples of this disclosure.

[0081] Figure 19D is a schematic diagram illustrating the motion process of the initial retraction of the joint involved in the example of this disclosure.

[0082] Figure 19E is a schematic diagram illustrating the movement process of the secondary retraction of the puncture member involved in the example of this disclosure.

[0083] Figure 20A is an exploded view showing a first embodiment of the puncture member according to the example of this disclosure.

[0084] Figure 20B is a schematic diagram showing a first view of the assembled first embodiment of the puncture member according to the example of this disclosure.

[0085] Figure 20C is a cross-sectional view showing a first embodiment of the puncture member according to the example of this disclosure.

[0086] Figure 20D is a schematic diagram showing a second view of the assembled first embodiment of the puncture member involved in the example of this disclosure.

[0087] Figure 20E is an exploded schematic diagram showing a second embodiment of the puncture member involved in the example of this disclosure.

[0088] Figure 20F is a schematic diagram showing a first view of the assembled second embodiment of the puncture member involved in the example of this disclosure.

[0089] Figure 20G is a schematic diagram showing a support seat in a second embodiment of the puncture member according to the example of this disclosure.

[0090] Figure 20H is a cross-sectional view showing a second embodiment of the puncture member involved in the examples of this disclosure.

[0091] Figure 20I is a schematic diagram showing a plurality of sharp object fixing arms in a second embodiment of the puncture member involved in the examples of this disclosure.

[0092] Figure 20J is a schematic diagram showing a second view of the assembled second embodiment of the puncture member involved in the example of this disclosure.

[0093] Figure 20K is a cross-sectional view illustrating a third embodiment of the puncture member involved in the examples of this disclosure.

[0094] Figure 20L is a cross-sectional view illustrating a fourth embodiment of the puncture member involved in the examples of this disclosure.

[0095] Figure 20M is a cross-sectional view illustrating a fifth embodiment of the puncture member involved in the examples of this disclosure.

[0096] Figure 20N is a cross-sectional view illustrating a sixth embodiment of the puncture member according to the examples of this disclosure.

[0097] Figure 21A is an exploded view from a first perspective of the sterilization assembly involved in the example of this disclosure.

[0098] Figure 21B is an exploded view of a second perspective of the sterilization component involved in the example of this disclosure.

[0099] Figure 22A is a structural schematic diagram showing a first-view view of the base involved in the example of this disclosure.

[0100] Figure 22B is a structural schematic diagram showing a second view of the base involved in the example of this disclosure.

[0101] Figure 23 is a schematic diagram illustrating the structure of the sensor involved in the example of this disclosure.

[0102] Figure 24 is a schematic diagram showing the sensor disposed on the base according to the example of this disclosure.

[0103] Figure 25A is a schematic diagram showing a first embodiment of the sealing cap according to an example of this disclosure, which is covered on a support portion.

[0104] Figure 25B is a cross-sectional view along the XX section line in Figure 25A.

[0105] Figure 25C is a structural schematic diagram from a first perspective illustrating a first embodiment of the sealing cap according to an example of this disclosure.

[0106] Figure 25D is a structural schematic diagram from a second perspective of a first embodiment of the sealing cap according to the example of this disclosure.

[0107] Figure 26 is a schematic diagram illustrating the structure of the sharp object involved in the example of this disclosure.

[0108] Figure 27 is a schematic diagram showing the structure of the first sealing element involved in the example of this disclosure.

[0109] Figure 28A is a schematic diagram showing a first-view view of a sharp object assembled on a base according to an example of this disclosure.

[0110] Figure 28B is a schematic diagram showing a second view of a sharp object assembled on a base according to an example of this disclosure.

[0111] Figure 28C is a schematic diagram showing the limited depth portion abutting against the sealing cap according to the example of this disclosure.

[0112] Figure 28D is a schematic diagram illustrating a second embodiment of the base according to the example of this disclosure.

[0113] Figure 28E is an exploded view showing a second embodiment of the base, sealing cover, and sensor involved in the example of this disclosure.

[0114] Figure 28F is a schematic diagram showing the assembly of the second embodiment of the base, the sealing cover, and the sensor according to the example of this disclosure.

[0115] Figure 28G is a schematic diagram illustrating a second embodiment of the sealing cap according to the example of this disclosure.

[0116] Figure 29A is a schematic diagram illustrating the structure of the cap involved in the example of this disclosure.

[0117] Figure 29B is a cross-sectional view of the cap of Figure 29A as described in this disclosure example, along the YY section line.

[0118] Figure 29C is a structural schematic diagram illustrating another embodiment of the cap according to the example of this disclosure.

[0119] Figure 29D is a cross-sectional view of the cap of Figure 29C, which is related to the example of this disclosure, along the ZZ section line.

[0120] Figure 30A is a schematic diagram showing a first-view view of the cap being assembled on the base according to an example of this disclosure.

[0121] Figure 30B is a schematic diagram showing a second view of the cap being assembled on the base according to an example of this disclosure.

[0122] Figure 30C is a cross-sectional view showing the sterilization component involved in the example of this disclosure.

[0123] Figure 31A is a schematic diagram showing the cap before coupling with a sharp object, as described in the example of this disclosure.

[0124] Figure 31B is a schematic diagram showing the coupling of a cap with a sharp object according to an example of this disclosure.

[0125] Figure 32A is a schematic diagram showing the cap and base before coupling, as described in the example of this disclosure.

[0126] Figure 32B is a schematic diagram showing another perspective of the cap and base before coupling, as described in the example of this disclosure.

[0127] Figure 32C is a schematic diagram showing the cap and base coupled according to the example of this disclosure.

[0128] Figure 32D is a schematic diagram showing another perspective of the cap coupled to the base as described in the example of this disclosure.

[0129] Figure 33A is a schematic diagram showing the electronic device and base involved in the example of this disclosure before assembly.

[0130] Figure 33B is a schematic diagram showing the electronic device and base according to the example of this disclosure after assembly.

[0131] Figure 33C is a schematic diagram showing the spring and connector before assembly according to the example of this disclosure.

[0132] Figure 33D is a schematic diagram showing the spring and connector assembly involved in the example of this disclosure.

[0133] Figure 33E is a schematic diagram illustrating the structure of the connector involved in the example of this disclosure.

[0134] Figure 33F is a schematic diagram illustrating another embodiment of the base, spring, and circuit board involved in the examples of this disclosure.

[0135] Figure 33G is an exploded view showing the base, spring, and circuit board in Figure 33F.

[0136] Figure 33H is a schematic diagram showing another perspective of the shrapnel in Figure 33F.

[0137] Figure 34A is a schematic diagram illustrating the assembly of the top cover and base according to the example of this disclosure.

[0138] Figure 34B is a schematic diagram illustrating the assembly of the top cover and base according to an example of this disclosure.

[0139] Figure 34C is a magnified schematic diagram of region A in Figure 34B.

[0140] Figure 35 is a schematic diagram showing the assembly of the housing with the sterilization assembly containing the electronic device and the top cover according to the example of this disclosure. Detailed Implementation

[0141] Hereinafter, preferred embodiments of the present disclosure will be described in detail with reference to the accompanying drawings. In the following description, the same reference numerals are used for the same components, and repeated descriptions are omitted. Furthermore, the drawings are merely schematic diagrams, and the proportions of the components or the shapes of the components may differ from actual figures.

[0142] It should be noted that the terms "comprising" and "having" and any variations thereof in this disclosure, such as a process, method, system, product, or device that includes or has a series of steps or units, are not necessarily limited to those steps or units that are explicitly listed, but may include or have other steps or units that are not explicitly listed or that are inherent to such processes, methods, products, or devices.

[0143] It should be noted that in this article, relative position and direction terms such as "above", "facing upward", "below", "facing downward", "up and down direction", "left side", "facing left side", "left", "facing left side", "right side", "facing right side", "right side", "facing right side", "left and right direction", "front", "facing forward", "back", "facing backward", and "front and back direction" are used with reference to the usual operating posture and should not be considered as restrictive.

[0144] First, let me introduce the relevant terminology used in this disclosure.

[0145] "Decoupling" can refer to removing coupling.

[0146] "Tightness" can refer to the degree of tightness between components.

[0147] In some examples, the analyte monitoring system disclosed herein may also be referred to as an analyte monitoring device, analyte monitor, analyte concentration information acquisition device, or biomonitoring device, etc. Additionally, the sensors involved in the examples of this disclosure may also be referred to as monitoring probes, sensing probes, or electrode probes, etc.

[0148] In this disclosure, the analyte monitoring system can target one or more of the following: glucose, acetylcholine, amylase, bilirubin, cholesterol, human chorionic gonadotropin (hCG), creatine kinase, creatine, creatine anhydride, DNA, fructosamine, glutamine, growth hormone, hormones, ketone bodies, lactate, oxygen, peroxides, prostate-specific antigen (PSA), prothrombin, RNA, thyroid-stimulating hormone (TSH), or troponin. In some examples, different analyte levels can be obtained by changing the sensing layer of the sensor.

[0149] For ease of description, the following description uses glucose as the analyte and glucose concentration as the corresponding analyte level. It should be noted that this does not constitute a limitation of this disclosure, and unless there is a contradiction, the description applies equally to other analyte levels.

[0150] The analytical substance monitoring system described in this disclosure is illustrated below with reference to the accompanying drawings.

[0151] Figure 1 is an application overview diagram illustrating the analyte monitoring system 1 according to an example of this embodiment. In some examples, the analyte monitoring system 1 may include a medical device 800 and an application device 1000, wherein the medical device 800 may be applied to a host via the application device 1000, and the host may obtain physiological information through the medical device 800 applied to itself. In some examples, the medical device 800 may be applied to a desired location. In this disclosure, the medical device 800 may also be referred to as a monitoring device 800.

[0152] In some examples, the analyte monitoring system 1 may include a reading device 900 (see Figure 1) that is communicatively connected to the medical device 800. The medical device 800, applied to the host, may transmit the acquired physiological information to the reading device 900, for example, wirelessly, thereby enabling the host to read and monitor its own physiological information.

[0153] In addition, this disclosure also provides an instrument kit 90, which may include the application device 1000 disclosed herein for applying the medical device 800 to a host.

[0154] In some examples, medical device 800 can be configured to acquire the host's analyte levels. In some examples, medical device 800 can be a sensing device. In some examples, medical device 800 can be an analyte sensor device that can generate information about a specific analyte in the body fluid based on the body fluid, such as reacting with the analyte in the body fluid and generating analyte information. In this case, the sensor 820 reacts with the analyte in the body fluid, thereby facilitating the acquisition of analyte information in the body fluid. For example, medical device 800 can be applied to the host's body surface and at least partially located under the host's skin to acquire the host's subcutaneous glucose concentration.

[0155] The following describes the medical device 800 involved in the examples of this disclosure. It should be noted that, for other analytes, those skilled in the art can perform analysis on other analytes by making slight modifications to the medical device 800 used to obtain glucose levels.

[0156] Figure 2 is a schematic diagram showing a first view of the medical device 800 according to the present disclosure example. Figure 3 is a schematic diagram showing a second view of the medical device 800 according to the present disclosure example.

[0157] In some examples, the medical device 800 may include a sensor 820 and an applicator 860 (see Figure 2 or Figure 3). In some examples, the sensor 820 may be supported on the applicator 860. In this disclosure, the applicator 860 may also be referred to as a body unit 860.

[0158] In some examples, sensor 820 can be placed partially or entirely under the skin of the host. In other words, sensor 820 can be placed at least partially under the skin. This allows for the monitoring of physiological information in the subcutaneous tissue fluid.

[0159] In some examples, after being placed subcutaneously, sensor 820 can react with glucose in the subcutaneous tissue fluid to generate glucose information for the host. The patch 860 can be applied to the host's body surface. In some examples, patch 860 can also receive the glucose information generated by sensor 820. In some examples, patch 860 can also provide the sensor 820 with the electrical energy required to acquire physiological information. This facilitates continuous monitoring by sensor 820 under the host's skin.

[0160] In some examples, sensor 820 may have an implantable portion that can be implanted under the host's skin. In some examples, the implantable portion of sensor 820 may be elongated. In some examples, the implantable portion may be rigid. This facilitates placement under the host's skin. In other examples, the implantable portion may also be flexible, in which case the host's foreign body sensation can be reduced. In some examples, after the implantable portion is implanted into the host, its depth can reach the dermis and be located in the interstitial space of the skin, so that sensor 820 can collect glucose information from the interstitial fluid.

[0161] In some examples, the dressing portion 860 may also include a hole 862 extending from the upper surface to the lower surface (see Figure 2 or Figure 3), and when the sensor 820 is fitted onto the dressing portion 860, the axis of the sensor 820 may pass through the hole 862. In this case, a sharp object 270 (described later) can be inserted subcutaneously through the hole, thereby facilitating the placement of the sensor 820 subcutaneously.

[0162] In some examples, the implantation site may include a working electrode and a counter electrode. In this disclosure, a sensing layer including a glucosidase may be disposed on the working electrode. The sensor 820, placed subcutaneously, can generate a current signal by reacting with glucose in tissue fluid or blood via the glucosidase on the working electrode, forming a circuit with the counter electrode. This current signal is then analyzed to obtain glucose concentration information. In some examples, the current signal generated by the sensor 820 can be transmitted to the dressing 860.

[0163] In some examples, the implantation site may also include a reference electrode. In some examples, the reference electrode may form a known and fixed potential difference with the tissue fluid or blood. In this case, the potential difference between the working electrode and the tissue fluid or blood can be measured by the potential difference formed between the reference electrode and the working electrode. This allows for a more accurate determination of the voltage generated by the working electrode. Consequently, the electronics 880 of the dressing 860 (described later) can automatically adjust and maintain a stable voltage at the working electrode according to a preset voltage value, so that the measured current signal can more accurately reflect the glucose concentration information in the tissue fluid or blood. In some examples, the number of reference electrodes may be one or more, for example, two.

[0164] In some examples, the applicator 860 is configured to adhere to the surface of a host. In some examples, an adhesive patch 870 (see Figure 2 or Figure 3) is provided on one side of the applicator 860 for adhesion to the host. The applicator 860 can be applied to and secured to the surface of the host via the adhesive patch 870.

[0165] In some examples, the adhesive sheet 870 may be part of the application portion 860. That is, the application portion 860 may also include the adhesive sheet 870 with adhesive properties.

[0166] Figure 4 is a block diagram illustrating the electronic device 880 of the medical device 800 according to the example of this disclosure.

[0167] In some examples, referring to Figure 4, the dressing portion 860 may also include an electronic device 880. The electronic device 880 can receive glucose information generated by the sensor 820. In some examples, the electronic device 880 can further process the glucose information. In other examples, the electronic device 880 can also transmit the received glucose information to an external device, such as the reading device 900 described below. Additionally, the electronic device 880 can also power the sensor 820.

[0168] In some examples, electronic device 880 may include a power supply module 882, a switch module 884, and a processing module 886 (see Figure 4). The power supply module 882 can supply power to the sensor 820 and / or the processing module 886, the switch module 884 can control the on / off state between the power supply module 882 and the sensor 820 and / or the processing module 886, and the processing module 886 can process the signal (e.g., glucose information) generated by the sensor 820.

[0169] In some examples, the applicator 860 has an initial mode configured as an open circuit and an operating mode configured as a closed circuit. In this case, the applicator 860 is configured as an open circuit when in the initial mode, thereby saving power consumption before the applicator 860 enters the operating state. In some examples, the switch module 884 can be in an open state when the applicator 860 is configured as the initial mode, and the switch module 884 can be in a closed state when the applicator 860 is configured as the operating mode. That is, the switch module 884 can switch the applicator 860 from the initial mode to the operating mode. In this case, controlling the switching of the applicator 860 from the initial mode to the operating mode by the switch module 884 can effectively reduce power consumption before operation.

[0170] In some examples, the electronic device 880 may also include a storage module 888 (see Figure 4). The storage module 888 can store the signals generated by the sensor 820. Additionally, in some examples, the electronic device 880 may also include a communication module 890 (see Figure 4). The communication module 890 can communicate with external devices (e.g., smart terminal devices). In some examples, the communication module 890 can be a Bluetooth module, an NFC module, a Wi-Fi module, etc. In some examples, the smart terminal device can be a smartphone, a smartwatch, a tablet, a computer, etc.

[0171] In some examples, the applicator 860 can be configured to be activated from an initial mode to an operating mode by magnetic or optical action. In this case, activating the applicator 860 from the initial mode to the operating mode by a non-contact component such as magnetic or optical action can help to miniaturize the applicator 860.

[0172] In other examples, the switch module 884 may also be configured as a magnetically controlled switch. For example, in the initial mode, the switch module 884 may be in an open state, and when the magnetic force acting on the switch module 884 changes, the switch module 884 may switch from the open state to the closed state, thereby activating the applicator 860 from the initial mode to the working mode.

[0173] In some examples, the application device 1000 may include a magnet. When the medical device 800 is not yet applied to the host, the switching module 884 of the electronic device 880 may be in an open state because the electronic device 880 of the medical device 800 is currently near the magnet. When the medical device 800 is applied to the host, the switching module 884 of the electronic device 880 may be activated to a closed state because the electronic device 880 of the medical device 800 is currently away from the magnet.

[0174] Additionally, in some examples, the power module 882 of the electronic device 880 can also be configured to provide power to the sensor 820. In some examples, when the electronic device 880 is in an initial mode, the power module 882 can be disconnected from the sensor 820, and when the electronic device 880 is activated to an operating mode (i.e., when the switch module 884 is closed), the power module 882 can be connected to the sensor 820 to provide power to the sensor 820.

[0175] In some examples, as described above, the applicator 860 can be configured to communicate with an external device via wireless or wired communication. In this case, by configuring the applicator 860 to communicate with an external device, the analyte information acquired by the sensor 820 can be read in real time or periodically. In some examples, the external device can be a reading device 900.

[0176] In some examples, as described above, the medical device 800 can communicate with the reading device 900. In some examples, the reading device 900 can be a display with communication capabilities. In some examples, the communication function of the reading device 900 can be implemented through wireless or wired communication. Wireless communication methods can include Bluetooth, NFC, Wi-Fi, etc. Wired communication methods can include USB, fiber optic, etc.

[0177] In other examples, the reading device 900 may also be a smart terminal with an application installed that is compatible with the medical device 800. The smart terminal can be a laptop, tablet, smartphone, etc.

[0178] As described above, the medical device 800 of this disclosure can be applied to a host via the application device 1000. Hereinafter, the analyte monitoring system 1 of this disclosure will be described in detail with reference to the accompanying drawings.

[0179] Figure 5A is a first-view overall appearance schematic diagram of the analyte monitoring system 1 according to the present disclosure example; Figure 5B is a first-view cross-sectional schematic diagram of the analyte monitoring system 1 according to the present disclosure example. Figure 5C is a first-view overall appearance schematic diagram of another embodiment of the analyte monitoring system 1 according to the present disclosure example; Figure 5D is a cross-sectional schematic diagram of the analyte monitoring system 1 of Figure 5C according to the present disclosure example along section line AA. Figure 5E is a schematic diagram of the cap 700 and the housing 10 of Figure 5D according to the present disclosure example after being screwed relative to each other. Figure 6 is a second-view overall appearance schematic diagram of the analyte monitoring system 1 according to the present disclosure example. Figure 5A shows a schematic diagram of the cap 700 and the housing 10 when coupled, and Figure 5B does not show the sensor 820.

[0180] In some examples, referring to Figures 5A and 5B, the analyte monitoring system 1 of this disclosure is a single-unit structure, with the medical device 800 pre-assembled into the application device 1000 at the factory stage. The analyte monitoring system 1 can be provided to the user in a single package, allowing the user to directly apply the medical device 800 to the host via the application device 1000 without any assembly steps during use.

[0181] In some examples, referring to Figure 5B, the analyte monitoring system 1 may include an application device 1000 and a medical device 800. In some examples, the medical device 800 may be releasably held in the application device 1000.

[0182] In some examples, the analyte monitoring system 1 may include a cap 700 coupled to the application device 1000. In some examples, the cap 700 may have a sealed space that accommodates at least a portion of the sensor 820. This allows at least a portion of the sensor 820 to be isolated from external contaminants.

[0183] In some examples, referring to Figure 5B, the application device 1000 may include a housing 10. In some examples, a cap 700 may be coupled to the housing 10. Thus, a medical device 800 can be covered within the application device 1000.

[0184] In some examples, the cap 700 may be removably coupled to the housing 10. In some examples, removing the cap 700 may expose the medical device 800 held in the application device 1000. In some examples, when the cap 700 is removed, a user may use the application device 1000 to apply the medical device 800 to the host.

[0185] In some examples, referring to Figure 5A, the dimensions of the end of the housing 10 near the cap 700 can match the dimensions of the cap 700. For example, the inner diameter of the end of the housing 10 near the cap 700 can be the same as the outer diameter of the cap 700. This improves the tightness of the coupling between the housing 10 and the cap 700.

[0186] In some examples, referring to Figure 5A, the housing 10 may have a cylindrical profile. In this case, it facilitates the user's application of force to the housing 10, thereby facilitating the relative screwing of the housing 10 and the cap 700 to expose the medical device 800. In some examples, referring to Figure 5C, the housing 10 may have an elliptical profile.

[0187] Unless otherwise specified, the following explanation will use the analyte monitoring system 1 in Figure 5A as an example.

[0188] As described above, the medical device 800 may include a sensor 820 and an applicator 860. The sensor 820 may extend from the bottom of the applicator 860. In some examples, the cap 700 is configured to provide a sealed space for the tail 821 of the sensor 820. This allows for the isolation of external contaminants before the sensor 820 is implanted into the host.

[0189] In some examples, referring to Figure 5B, the instrument kit 90 may include a sharp object 270. In some examples, the sharp object 270 may be configured such that its tail 821, carrying a sensor 820, penetrates the subcutaneous tissue of the host.

[0190] In some examples, the cap 700 may be coupled to at least one of the medical device 800 or the sharp object 270 to form a sealed space accommodating at least a portion of the sensor 820. For example, the cap 700 may be coupled to the medical device 800, or to the sharp object 270, or simultaneously to both the medical device 800 and the sharp object 270 to form the aforementioned sealed space.

[0191] In some examples, the cap 700 may also be configured to provide a sealed space for the tail of the sharp object 270. In some examples, the sharp object 270 may pass through the applicator 860 and extend from the bottom of the applicator 860, and the portion of the sharp object 270 extending out of the applicator 860 may be accommodated in the sealed space.

[0192] In some examples, the sharp object 270 may have a space for carrying and accommodating the sensor 820, which may be at least partially accommodated within the sharp object 270. In some examples, the sharp object 270 and the sensor 820 may be at least partially located within the aforementioned sealed space.

[0193] In some examples, the sharp object 270 may not have space to support and accommodate the sensor 820. In this case, the angle between the sensor 820 and the sharp object 270 can be properly set so that the tail 821 of the sensor 820 fits against the sharp object 270.

[0194] In some examples, referring to Figure 5B, the cap 700 may include a mating portion 720. In some examples, the mating portion 720 may be coupled to at least one of the medical device 800 and the sharp object 270. This allows for the formation of a sealed space accommodating at least a portion of the sensor 820.

[0195] In some examples, the mating part 720 has a chamber 710 configured to receive at least a portion of the sensor 820. In some examples, the tail of the sharp object 270 and the tail 821 of the sensor 820 can be jointly received in the chamber 710. Thus, a sealed space can be provided for the tail of the subcutaneously penetrable sharp object 270 and the tail 821 of the subcutaneously implanted sensor 820.

[0196] In some examples, referring to FIG5B, the sharp object 270 may have a needle-like portion 272 and a cap portion 276. The mating portion 720 may couple with the end of the cap portion 276 near the applicator portion 860 to form the aforementioned sealing space. In some examples, the mating portion 720 may form the sealing space by relative screwing with the end of the cap portion 276 near the applicator portion 860. In some examples, the sealing space may also be formed by snap-fit, male-female mating, or other methods.

[0197] In some examples, the cap 700 may include a bottom cover 770 that engages with the mating portion 720. In some examples, the bottom cover 770 may be coupled to the housing 10 of the application device 1000. In some examples, the bottom cover 770 may be removably coupled to the housing 10.

[0198] Figure 7A is a schematic diagram showing a first state in which the cap 700 is decoupled from the housing 10 according to an example of this disclosure. Figure 7B is a schematic diagram showing a second state in which the cap 700 is decoupled from the housing 10 according to an example of this disclosure.

[0199] In some examples, referring to Figures 5A and 7A, the housing 10 may have a joining feature 191, and the bottom cover 770 may have a joining feature 791. For ease of description, the joining feature 191 of the housing 10 will be referred to as the first joining feature 191, and the joining feature of the bottom cover 770 will be referred to as the second joining feature 791.

[0200] In some examples, the bottom cover 770 can be coupled to the housing 10 by the engagement of the first engagement feature 191 and the second engagement feature 791.

[0201] In some examples, the end of the application device 1000 that is away from the host during use may be referred to as the distal end, and the end of the application device 1000 that is facing the host during use may be referred to as the proximal end. In some examples, referring to FIG. 7B, the first engagement feature 191 may have a first engagement surface 1911 facing the distal end. In some examples, referring to FIG. 7B, the second engagement feature 791 may have a second engagement surface 7911 facing the proximal end. When the first engagement surface 1911 abuts against the second engagement surface 7911, the cap 700 may be coupled to the housing 10. Here, the distal end may refer to the end of the application device 1000 that is away from the host during use, and the proximal end may refer to the end of the application device 1000 that is facing the host during use.

[0202] In some examples, the housing 10 may include a proximal end portion having a first engagement feature 191. In some examples, the first engagement feature 191 may extend circumferentially along the housing 10. In some examples, the first engagement feature 191 may be an annular opening formed at the proximal end portion (see FIG. 7B). In some examples, the first engagement feature 191 may be formed as a guide groove at the proximal end portion, such as an annular groove formed as the inner wall of the proximal end portion.

[0203] As described above, the bottom cover 770 may have a second engagement feature 791. In some examples, the second engagement feature 791 may be a protrusion formed on the periphery of the bottom cover 770 (see FIG. 7B). In some examples, the second engagement feature 791 may be a spring arm formed on the periphery of the bottom cover 770 (see FIG. 29C, described later).

[0204] In some examples, the bottom cover 770 can move along the first engagement feature 191 to separate from the application device 1000. In some examples, the bottom cover 770 can move along the first engagement feature 191 to disengage the first engagement feature 191 and the second engagement feature 791 to decouple the bottom cover 770 and the application device 1000.

[0205] In some examples, during the decoupling of the cap 700 from the housing 10, the second engagement feature 791 and the first engagement feature 191 can move relative to each other. In some examples, the second engagement feature 791 can move along the extension path of the first engagement feature 191. In some examples, the movement path of the second engagement feature 791 relative to the first engagement feature 191 can be an arc.

[0206] In some examples, the engagement of the first engagement feature 191 and the second engagement feature 791 can be disengaged by relatively twisting the housing 10 and the cap 700. In some examples, the cap 700 can be disengaged from the housing 10 by rotating it relative to the housing 10 by a preset angle.

[0207] In some examples, the cap 700 can be decoupled from the sharp object 270 in response to decoupling from the housing 10. In some examples, the medical device 800 held in the application device 1000 can be exposed by relatively twisting the housing 10 and the cap 700.

[0208] The angle of the arc corresponding to the movement path of the second engagement feature 791 relative to the first engagement feature 191 is set to the aforementioned preset angle. In some examples, the preset angle may be the same as the angle at which the cap 700 is coupled to the sharp object 270. In some examples, the relative turning direction when decoupling the cap 700 and the housing 10 may be opposite to the relative turning direction when coupling the cap 700 and the sharp object 270.

[0209] In some examples, the angle corresponding to the path defined by the first engagement feature 191 can be equal to a preset angle. Thus, when the second engagement feature 791 is moved from the starting position to the ending position along the first engagement feature 191, the cap 700 can be decoupled from the housing 10.

[0210] In some examples, the angle corresponding to the path defined by the first engagement feature 191 can be greater than a preset angle. The user can rotate the second engagement feature 791 along the extension path of the first engagement feature 191 by a preset angle through observation or other means to decouple the cap 700 from the housing 10.

[0211] In some examples, referring to Figure 5A, the housing 10 may have a first indicator 192, and the cap 700 may have a second indicator 792. In some examples, the cap 700 is coupled to the housing 10 when the first indicator 192 and the second indicator 792 are aligned. When the analyte monitoring system 1 is removed from the packaging, it can be determined whether the analyte monitoring system 1 has undergone any undesirable morphological changes before use based on whether the first indicator 192 and the second indicator 792 are aligned.

[0212] In some examples, during the decoupling of the cap 700 from the housing 10, the first indicator 192 and the second indicator 792 can move relative to each other. In some examples, the movement path of the second indicator 792 relative to the first indicator 192 can be an arc, and the angle corresponding to the arc can be equal to a preset angle.

[0213] In some examples, after the cap 700 is screwed relative to the housing 10 at a preset angle, the cap 700 can then be moved away from the housing 10 to decouple it from the housing 10 (see Figures 5A, 7A and 7B).

[0214] Figure 8A is a schematic diagram showing a first view of a first embodiment of the housing 10 according to the present disclosure example; Figure 8B is a schematic diagram showing a second view of a first embodiment of the housing 10 according to the present disclosure example.

[0215] In some examples, referring to Figures 8A and 8B, housing 10 may have a decoupling groove 193. In some examples, decoupling groove 193 may communicate with first engagement feature 191. In some examples, decoupling groove 193 may be configured to provide a path for decoupling cap 700 from housing 10. In some examples, decoupling groove 193 may be located at one end of first engagement feature 191, for example, at the end position of first engagement feature 191.

[0216] In some examples, the second engagement feature 791 can move from the end of the first engagement feature 191 away from the decoupling groove 193 to the end near the decoupling groove 193. In some examples, when the second engagement feature 791 moves to the end of the first engagement feature 191 near the decoupling groove 193, the second engagement feature 791 can enter the decoupling groove 193. In some examples, the second engagement feature 791 can move away from the housing 10 along the extending direction of the decoupling groove 193. Thus, the decoupling of the cap 700 and the housing 10 can be completed.

[0217] In some examples, the housing 10 may have at least one first engagement feature 191, for example, one, two, three, or four first engagement features 191. In some examples, when the housing 10 has multiple first engagement features 191, the multiple first engagement features 191 may be symmetrically arranged near the proximal end of the housing 10. This allows for stable coupling of the cap 700 to the application device 1000. In some examples, the number of second engagement features 791 may be the same as the number of first engagement features 191.

[0218] Figure 9A is a schematic diagram illustrating a second embodiment of the housing 10 according to an example of this disclosure. Figure 9B is a schematic diagram illustrating a third embodiment of the housing 10 according to an example of this disclosure. Figure 10A is a schematic diagram illustrating a cap 700 that mates with the housing 10 of Figure 9A. Figure 10B is a schematic diagram illustrating a cap 700 that mates with the housing 10 of Figure 9B.

[0219] In some examples, housing 10 may be coupled to cap 700 in such a way that it is at least partially received in cap 700.

[0220] In some examples, as described above, the first engagement feature 191 may have a first engagement surface 1911 facing the distal end. In some examples, as described above, the second engagement feature 791 may have a second engagement surface 7911 facing the proximal end. When the first engagement surface 1911 abuts against the second engagement surface 7911, the cap 700 may be coupled to the housing 10.

[0221] In some examples, referring to Figures 9A and 9B, the first joining feature 191 may be a circumferential rib formed near the proximal end. In some examples, referring to Figures 10A and 10B, the second joining feature 791 may be a circumferential rib formed on the cap 700.

[0222] In some examples, a decoupling structure may be present between two adjacent first engagement features 191. In some examples, the second engagement feature 791 can be disengaged from the first engagement feature by relative rotation of the cap 700 and the housing 10. This allows the cap 700 to be decoupled from the housing 10. In some examples, the decoupling structure may refer to a portion near the end where no other structure is formed, for example, a portion where the first engagement feature 191 is not formed; in this case, there is no need to additionally provide the decoupling groove 193 mentioned above. Thus, when the second engagement feature 791 is operated to correspond to the decoupling structure, it can be released in a direction away from the housing 10, thereby decoupling the cap 700 and the housing 10.

[0223] In some examples, at least a portion of the structure of the second engagement feature 791 may be a tearable feature. In some examples, referring to FIG10B, the tearable feature may have a breakable portion 713. In some examples, the breakable portion can be removed in a direction away from the central axis CA. This allows for at least partial disengagement of the engagement between the first engagement feature 191 and the second engagement feature 791.

[0224] In some examples, referring to Figure 10B, the breakable portion may be formed with discontinuous circumferential ribs, and the cap 700 may be connected to the housing 10 when the discontinuous circumferential ribs abut against the first engagement feature 191. When the tearable feature is torn open, the discontinuous circumferential ribs may disengage from the first engagement feature 191. In some examples, the breakable portion may also be formed with continuous circumferential ribs.

[0225] In some examples, referring to FIG10B, the tearable feature may have a protrusion 7131. In some examples, the protrusion may be attached to the breakable portion. This facilitates user removal of the breakable portion. In some examples, the protrusion 7131 may serve as a second indicator 792 of the cap, cooperating with the first indicator 192 of the housing 10. The functions of the first indicator 192 and the second indicator 792 can be referred to the relevant description in the first embodiment of the housing 10 according to this disclosure.

[0226] In some examples, the second engagement feature 791 includes a circumferential rib disposed opposite to the tearable feature. When the tearable portion is removed, the engagement of the second engagement feature 791 with the circumferential rib disposed opposite to the tearable feature can be released by relative rotation of the cap 700 and the housing 10. This allows the engagement between the cap 700 and the housing 10 to be made accessible.

[0227] Embodiments of this disclosure include:

[0228] A. A method of using an analyte monitoring system, the analyte monitoring system comprising an application device having a housing, a cap removably coupled to the housing, a medical device held in the application device, and a sharp object fitted to the medical device, the method of use comprising: relative screwing the housing and the cap to expose the medical device held in the application device, wherein the cap decouples from the sharp object in response to decoupling from the housing.

[0229] In some examples, Embodiment A may be combined with any one or more of the following additional elements: Element 1: The cap is rotated by a predetermined angle relative to the housing to decouple from the housing. Element 2: The housing includes a proximal end having a first engagement feature. Element 3: The first engagement feature extends circumferentially along the housing. Element 4: The first engagement feature is a guide groove, an annular opening, or a circumferential rib formed at the proximal end. Element 5: The cap has a second engagement feature. Element 6: The second engagement feature is a protrusion or circumferential rib formed on the cap. Element 7: The second engagement feature moves along the extension path of the first engagement feature. Element 8: The movement path of the second engagement feature relative to the first engagement feature is an arc, the angle corresponding to the arc being equal to the predetermined angle. Element 9: The housing has a first indicator portion, and the cap has a second indicator portion, wherein the first indicator portion and the second indicator portion move relative to each other during the decoupling of the cap from the housing. Element 10: The movement path of the second indicator relative to the first indicator is an arc, and the angle corresponding to the arc is equal to the preset angle. Element 11: After the cap and the housing are rotated relative to each other at the preset angle, the second engagement feature moves from one end of the first engagement feature to the other end, and the cap moves away from the housing to decouple from the housing. Element 12: In response to an action applied to the cap along the central axis of the application device, the second engagement feature is released along the decoupling groove. Element 13: The housing of the application device also has an engagement feature along which the bottom cover moves to separate from the application device.

[0230] Figure 11A is an exploded view of the analyte monitoring system 1 according to an example of this disclosure. Figure 11B is a first-view structural schematic diagram of another embodiment of the gasket 60 according to an example of this disclosure. Figure 11C is a second-view structural schematic diagram of the gasket 60 shown in Figure 11B according to an example of this disclosure.

[0231] In this disclosure, the device kit 90 may include an application device 1000 for applying a medical device 800 to a host. In some examples, referring to FIG11A, the application device 1000 may include a housing 10 providing a space for movement, and an auxiliary mechanism 20 (described later) configured to move within the space for movement of the housing 10. The housing 10 may have a proximal end that is close to the host during operation and a distal end that is distant from the host. The auxiliary mechanism 20 may be releasably retained in the housing 10 and may house the medical device 800. The auxiliary mechanism 20 may be configured to move relative to the housing 10 and be driven toward the host when released to apply the medical device 800 to the host. It is understood that, herein, "proximal end" may be understood as the end that is close to the host during operation, and "distal end" may be understood as the end that is distant from the host during operation.

[0232] In some examples, the housing 10 may have a movable space, and the auxiliary mechanism 20 may be releasably retained within the housing 10. In some examples, the auxiliary mechanism 20 may be movable within the movable space of the housing 10 when it is released. Additionally, in some examples, the housing 10 may also define the application site of the medical device 800 on the host's body surface.

[0233] In some examples, referring to FIG11A, housing 10 may include a first housing 100 and a second housing 140. In some examples, the second housing 140 may be fitted onto the first housing 100. The first housing 100 and the second housing 140, when fitted together, may form a space for movement. The first housing 100 may releasably hold the auxiliary mechanism 20. In some examples, the first housing 100 may define the application site of the medical device 800 on the host's body surface. In some examples, the second housing 140 may define the application site of the medical device 800 on the host's body surface.

[0234] In some examples, the second housing 140 may be fixedly assembled to the first housing 100. In some examples, the first housing 100 and the second housing 140 may be integrally formed.

[0235] In some examples, the second housing 140 may define a path of movement for the auxiliary mechanism 20. After being released by the first housing 100, the auxiliary mechanism 20 may move relative to the second housing 140 along the path defined by the second housing 140 and apply the medical device 800 to the application site. In this disclosure, the axes of the first housing 100 and the second housing 140 may be substantially parallel to the central axis CA of the application device 1000.

[0236] In some examples, referring to FIG11A, the auxiliary mechanism 20 may include a motion body 200 and a receiving portion 250. In some examples, the motion body 200 may be releasably held in the first housing 100. In some examples, the motion body 200 may be configured to move along a movement path defined by the second housing 140 when released. In some examples, the receiving portion 250 may be disposed in the motion body 200 and may be configured to releasably hold the medical device 800. In some examples, after release, the motion body 200 may move toward the proximal end of the housing 10, and the receiving portion 250 may also move toward the proximal end of the housing 10 to apply the medical device 800, received within the receiving portion 250, to the host.

[0237] In some examples, referring to Figure 11A, the instrument kit 90 may include a sharp object 270 and a support 280 for supporting the sharp object 270 and fitted to the moving body 200. Hereinafter, for ease of description, the sharp object 270 and the support 280 may be referred to as a whole as the puncture member 260.

[0238] In some examples, the puncture member 260 may be disposed within the moving body 200. When the moving body 200 is released, it can be driven proximally and, through the puncture member 260, place the medical device at least partially under the skin of the host. Specifically, the puncture member 260 may be disposed within the moving body 200 through the receiving portion 250. After the moving body 200 is released, it can move proximally towards the housing 10, and the receiving portion 250 and the puncture member 260 also move proximally towards the housing 10 to apply the medical device 800, received within the receiving portion 250, to the host. In some examples, the puncture member 260 may penetrate subcutaneously into the host, thereby placing the medical device 800 at least partially under the host's skin.

[0239] In some examples, the implantable subcutaneous component (e.g., a sensor) in the medical device 800 can have a certain degree of rigidity. Therefore, the sensor can be implanted subcutaneously without the need for the puncture member 260. In other words, the device kit 90 may also exclude the puncture member 260, allowing the sensor to be implanted subcutaneously based on its own rigidity.

[0240] In some examples, referring to FIG11A, the application device 1000 may further include a first drive mechanism 30. In some examples, the first drive mechanism 30 may be configured to apply an action to the auxiliary mechanism 20 in a proximal manner. In some examples, when the auxiliary mechanism 20 is released, the first drive mechanism 30 may drive the auxiliary mechanism 20 toward the host. Thus, the medical device 800, releasably held in the auxiliary mechanism 20, can be automatically applied to the host.

[0241] In some examples, the first actuation mechanism 30 may be configured to apply an action to the motion body 200 in a proximal manner. When the motion body 200 is released, it may be driven proximally by the first actuation mechanism 30 to push the medical device 800, housed within the receiving portion 250, toward the host, for example, toward the application site defined by the receiving housing 10. Alternatively, the medical device 800 may be at least partially placed subcutaneously in the host via the puncture member 260.

[0242] In other examples, the application device 1000 may not include the first drive mechanism 30. In this case, the motion body 200 may also be manually driven to move towards the proximal end when it is released.

[0243] Figure 12A is a perspective view of the first housing 100 according to an example of this disclosure; Figure 12B is a perspective view of the first housing 100 according to a second view. Figure 12C is a cross-sectional view of the first housing 100 according to an example of this disclosure. Figure 12D is a schematic diagram showing the first view of the first housing 100 shown in Figure 5C according to an example of this disclosure. Figure 12E is a schematic diagram showing the second view of the first housing 100 shown in Figure 5C according to an example of this disclosure.

[0244] In some examples, as described above, housing 10 may include a first outer shell 100. In some examples, the first outer shell 100 may be formed as a hollow cylindrical shell extending vertically along the central axis CA of the application device 1000. In some examples, the first outer shell 100 may be formed as a cylindrical shell with an opening only at its proximal end.

[0245] In some examples, referring to FIG12A, the first housing 100 may include a peripheral portion 110 and a distal portion 120. In some examples, the distal portion 120 may be formed on the peripheral portion 110 in a manner close to the distal end of the housing 10. In some examples, the central axis CA may pass through the geometric center of the distal portion 120.

[0246] In some examples, referring back to Figure 8A or Figure 8B, the first engagement feature 191 may be disposed on the first housing 100. In some examples, the first engagement feature 191 may be formed at the proximal end of the first housing 100. This facilitates coupling of the housing 10 with the cap 700.

[0247] In other examples, the first engagement feature 191 may also be provided on the second housing 140 (described later).

[0248] In some examples, referring to FIG12A, the first housing 100 may include a first retaining portion 130. In some examples, the first retaining portion 130 may be configured to releasably retain the moving body 200. In some examples, the first retaining portion 130 may be located at the distal end 120. In some examples, the first retaining portion 130 may extend from the distal end 120 along the central axis CA toward the proximal end of the application device 1000. In this case, when the moving body 200 is held at the distal end 120, the moving body 200 may be located within the hollow portion of the peripheral portion 110, and when the moving body 200 is released, the moving body 200 may move substantially along the axial direction of the peripheral portion 110. That is, when the moving body 200 is released, the moving body 200 may move substantially along the central axis CA.

[0249] In some examples, the first retaining part 130 can be releasably interlocked with the retained part (e.g., the first locking part 236 of the moving body 200, which will be described later below) by at least one of the following structures: a latch, a hook, a bolt, or a pin. In this case, the first retaining part 130 and the first locking part 236 are releasably interlocked by at least one of the following structures: a latch, a hook, a bolt, or a pin, thereby providing an interlocking method that is easy to release.

[0250] In some examples, the number of first retaining portions 130 can be one or more, such as 1, 2, 3, or 4. In some examples, if there are multiple first retaining portions 130, the multiple first retaining portions 130 can be symmetrically arranged at the end 120. In the embodiment shown in FIG12A, the number of first retaining portions 130 can be 1.

[0251] In some examples, the first holding portion 130 may have a distal surface, and the first locking portion 236 may have a proximal surface. When the moving body 200 is held, the distal surface of the first holding portion 130 and the proximal surface of the first locking portion 236 may engage with each other. In some examples, when the moving body 200 is released, the distal surface of the first holding portion 130 and the proximal surface of the first locking portion 236 may separate from each other.

[0252] In some examples, at least a portion of the first retaining part 130 may be L-shaped or hook-shaped. This facilitates the formation of a structure such as a snap fastener to interlock with the first locking part 236.

[0253] In some examples, referring to FIG12C, the first retaining portion 130 may include an arm 132 extending generally along the central axis CA, and a protrusion 134 linked to the arm 132 and projecting toward the central axis CA in a direction generally orthogonal to the central axis CA. In some examples, the arm 132 of the first retaining portion 130 may extend from the distal end 120. In this case, when the protrusion 134 of the first retaining portion 130 engages with the first locking portion 236, the first retaining portion 130 can be easily released from the first locking portion 236 by actuating the arm 132 to actuate the protrusion 134.

[0254] In some examples, the arm 132 of the first retaining portion 130 may be elastic. In some examples, the arm 132 of the first retaining portion 130 may be elastic in a direction substantially orthogonal to the central axis CA.

[0255] In some examples, the arm 132 of the first retaining part 130 may tend to contract toward the central axis CA in the direction from the distal end to the proximal end. That is, in the natural state (i.e., without external force), the end of the arm 132 closer to the proximal end is closer to the central axis CA than the end of the arm 132 closer to the distal end. In other examples, the arm 132 may also be approximately parallel to the central axis CA.

[0256] In some examples, arm 132 can pivot when acted upon in a direction generally orthogonal to the central axis CA. For instance, when acted upon in a manner away from the central axis CA and in a direction generally orthogonal to the central axis CA, arm 132 can pivot so that the proximal end of arm 132 moves away from the central axis CA. This allows for easy release of the held component.

[0257] In some examples, the first retaining portion 130 can swing when the arm 132 is acted upon in a direction generally orthogonal to the central axis CA. For example, when the arm 132 is acted upon in a manner away from the central axis CA and in a direction generally orthogonal to the central axis CA, the arm 132 can swing so that the proximal end of the arm 132 moves away from the central axis CA.

[0258] In some examples, the first retaining portion 130 can pivot or swing with the connection point between the first retaining portion 130 and the distal end portion 120 as the fulcrum.

[0259] In some examples, the arm 132 of the first retaining portion 130 can be brought closer to the central axis CA in the direction from the distal end to the proximal end, and the protrusion 134 of the first retaining portion 130 can protrude toward the central axis CA. In this case, the first locking portion 236 can be held on the inner side (near the central axis CA) by bringing the first retaining portion 130 inward as a whole, and the first locking portion 236 can be released by actuating the first retaining portion 130 on the outer side (away from the central axis CA), thereby facilitating the holding and releasing of the first locking portion 236.

[0260] In other examples, the arm 132 of the first retaining portion 130 may be moved away from the central axis CA in a direction from the distal end to the proximal end, and the protrusion 134 of the first retaining portion 130 may protrude away from the central axis CA. In this case, by dispersing the first retaining portion 130 as a whole outward, the first locking portion 236 can be retained on the outer side (away from the central axis CA), and by actuating the first retaining portion 130 toward the inner side (closer to the central axis CA), the first locking portion 236 can be released, thereby facilitating the retention and release of the first locking portion 236.

[0261] However, the examples disclosed herein are not limited thereto. The concept of the present invention is that the first retaining part 130 forms a structure such as a buckle, hook, latch, or pin to retain the retained part, and releases the retained part by removing the buckle, hook, latch, or pin from its original position. Based on this concept, the arm 132 of the first retaining part 130 and the protrusion 134 of the first retaining part 130 can also move closer or protrude in other directions when a buckle can be formed.

[0262] In some examples, the protrusion 134 of the first retaining portion 130 may have a distally facing surface. In some examples, the distally facing surface of the protrusion 134 may be approximately orthogonal to the central axis CA. The retained component (e.g., the first locking portion 236 of the moving body 200 described below) can be held in place and prevented from moving towards the proximal end by overlapping / abutting against the distally facing surface of the protrusion 134. When the arm 132 of the first retaining portion 130 is actuated to disengage the distally facing surface of the protrusion 134 from its original position, i.e., no longer abutting against the retained component, the retained component will be released.

[0263] In other words, the first retaining part 130 can be a structure such as a latch, hook, latch, or pin formed on the first housing 100 (e.g., the distal end 120 of the first housing 100). For example, the first retaining part 130 can be formed as a structure that can be decomposed into at least two parts, such as a finger-shaped, straight, L-shaped, J-shaped, or Z-shaped part, at least one part (e.g., an arm connected to the first housing 100) can pivot, and the other part (e.g., a protrusion protruding outward from the arm and abutting against the retained member) can move away from the initial position as it pivots, thereby releasing the hook, latch, top, support, etc., from the retained member.

[0264] In some examples, referring to FIG12B, the first housing 100 may include a first limiting portion 180. In some examples, the first limiting portion 180 may be configured to maintain the balance of the moving body 200 in a plane orthogonal to the central axis CA of the application device 1000. This reduces the probability of the moving body 200 wobbling, which could lead to the failure of the application device 1000.

[0265] In some examples, the first limiting portion 180 may extend generally along the central axis CA of the application device 1000. In some examples, the first limiting portion 180 may extend along the central axis CA in a direction from the distal end to the proximal end. In some examples, the first limiting portion 180 may be provided at the distal end 120. In some examples, the first retaining portion 130, the first limiting portion 180, and the first housing 100 may be integrally formed.

[0266] In some examples, the number of first limiting parts can be one or more. For example, the number of first limiting parts can be 1, 2, 3 or 4, etc.

[0267] In some examples, the number of first limiting portions 180 may be two. For example, referring to Figures 12A and 12B, the first limiting portions may include first limiting portion 180a and first limiting portion 180b. First limiting portions 180a and first limiting portions 180b may be disposed on opposite sides of the central axis CA. Preferably, first limiting portions 180a and first limiting portions 180b may be disposed on opposite sides of the central axis CA generally along the direction in which the first retaining portion 130 can be actuated. In this situation, since the first holding part 130 is in contact with the first locking part 236, when the first holding part 130 is actuated, the first locking part 236 will be subjected to the action applied by the first holding part 130 in the actuation direction of the first holding part 130 and / or in the opposite direction to the actuation direction, which will cause the moving body 200 to tend to wobble. However, the wobble of the moving body 200 can be suppressed by the action of the first limiting part 180. Thus, the assembly accuracy of the moving body 200 with other structural components (such as the second housing 140, the piercing member 260, etc.) can always be maintained.

[0268] In some examples, the first limiting part 180a may be an arm respectively disposed on both sides of the first holding part 130. In some examples, the second limiting part 180b may be disposed opposite to the first holding part 130.

[0269] Figure 13 is an exploded view showing the first housing 100, auxiliary mechanism 20, and first drive mechanism 30 involved in the example of this disclosure; Figure 14A is a cross-sectional view showing the moving body 200 involved in the example of this disclosure when it is held; Figure 14B is a cross-sectional view showing the moving body 200 involved in the example of this disclosure when it is released. It should be noted that Figures 14A and 14B mainly illustrate the holding and releasing of the moving body 200 by the first holding part 130, and do not illustrate the first drive mechanism 30 and other components.

[0270] In some examples, as described above, the auxiliary mechanism 20 may include a motion body 200 and a receiving portion 250 disposed on the motion body 200. The motion body 200 may be releasably held on the first housing 100. In some examples, the motion body 200 may be releasably held by a first holding portion 130. After being released, the motion body 200 may be driven proximally to push the medical device 800, housed within the receiving portion 250, toward the host.

[0271] In some examples, referring to Figure 13, a first drive unit 30 may be provided between the moving body 200 and the first housing 100. The first drive unit 30 can apply force to the moving body 200 in a proximal manner. After the moving body 200 is released, it can be driven proximal by the first drive unit 30 to push the medical device 800 housed in the receiving portion 250 toward the host.

[0272] In other examples, as described above, the application device 1000 may also exclude the first drive unit 30. In this case, when the motion body 200 is released, the motion body 200 may also be pushed toward the host by human force, thereby pushing the medical device 800 housed in the receiving part 250 toward the host.

[0273] In some examples, the moving body 200 may include a first bottom 210, a second bottom 220, and a sidewall 230 connecting the first bottom 210 and the second bottom 220 (see FIG13). The first bottom 210 may be located near the distal end, the second bottom 220 may be located near the proximal end, and the receiving portion 250 may be disposed on the second bottom 220.

[0274] In some examples, a hollow portion may be formed between the first bottom 210, the second bottom 220, and the sidewall 230. In some examples, the puncture member 260 may be disposed within the hollow portion of the moving body 200.

[0275] In some examples, the first drive mechanism 30 may be disposed between the auxiliary mechanism 20 and the first housing 100. In some examples, the two ends of the first drive mechanism 30 may abut against the first housing 100 and the auxiliary mechanism 20, respectively.

[0276] In some examples, the auxiliary mechanism 20 may include a positioning part 212 for positioning the first drive mechanism 30. In some examples, the positioning part 212 may be disposed on the second bottom 220. In some examples, the positioning part 212 may be disposed on the second bottom 220 in a manner surrounding the hollow portion. Thus, the first drive mechanism 30 can apply a stable driving force to the moving body 200 through the positioning part 212.

[0277] In some examples, the positioning portion 212 may be a protrusion extending distally from the second bottom 220 along the central axis CA. In some examples, the positioning portion 212 may be a columnar protrusion. In some examples, the positioning portion 212 may be cylindrical. In some examples, the distal end of the positioning portion 212 may have a groove for receiving the first drive mechanism 30. Thus, the first drive mechanism 30 can stably abut against the auxiliary mechanism 20.

[0278] In some examples, the positioning portion 212 may include a plurality of support frames 214 formed on the first bottom 210 and arranged around the hollow portion 200 (see FIG. 13). In some examples, the plurality of support frames 214 may be formed on the sidewall 230 and symmetrically arranged around the hollow portion. In some examples, the side of the support frame 214 near the distal end may have a groove 213 for supporting the first drive mechanism. Thus, the first drive mechanism 30 can stably abut against the plurality of support frames in a manner that fits the moving body to apply a stable driving force to the auxiliary mechanism.

[0279] In some examples, multiple support frames 214 may be formed on the sidewall 230 of the moving body 200. In some examples, the moving body 200 and the positioning part 212 may be integrally formed.

[0280] Figure 15A is an exploded schematic diagram showing a first view of the second housing 140 and auxiliary mechanism 10 according to an example of this disclosure. Figure 15B is an exploded schematic diagram showing a second view of the second housing 140 and auxiliary mechanism 10 according to an example of this disclosure. Figure 15C is an exploded schematic diagram showing a third view of the second housing 140 and auxiliary mechanism 10 according to an example of this disclosure. Figure 15D is a schematic diagram showing a first view of the second housing 140 shown in Figure 5C according to an example of this disclosure. Figure 15E is a schematic diagram showing a second view of the second housing 140 shown in Figure 5C according to an example of this disclosure.

[0281] In some examples, the second housing 140 may have an opening slot 141 through which the positioning part 212 extends (see FIG. 15A). Thus, during the assembly of the auxiliary mechanism 20 into the second housing 140, the positioning part 212 can extend through the second housing 140 to abut against the first drive structure 30.

[0282] In some examples, the positioning part 212 may be provided at the first bottom 210. In this case, the positioning part 212 can also more stably define the position at which the first drive mechanism 30 applies force to the moving body 200.

[0283] In some examples, the first drive mechanism 30 may have an energy storage state and an energy release state. When the first drive mechanism 30 switches from the energy storage state to the energy release state, it can release energy and act on the moving body 200 in a proximal manner. When the moving body 200 is held, the first drive mechanism 30 may exist in the energy storage state between the moving body 200 and the first housing 100. When the moving body 200 is released, the first drive mechanism 30 may switch from the energy storage state to the energy release state and act on the moving body 200 in a proximal manner.

[0284] In some examples, the first drive mechanism 30 can have a compressed state and an extended state, and can release energy when switching from the compressed state to the extended state. In some examples, the first drive mechanism 30 can be a compressible elastic component. In some examples, the first drive mechanism 30 can be a spring. Thus, an actuation mechanism for the moving body 200 can be provided through a simplified structural design.

[0285] In some examples, referring to Figures 12A or 12B, the distal end 120 may have a positioning portion 122. In some examples, the positioning portion 122 may be cylindrical. In this case, the other end of the first drive mechanism 30 may be fitted onto the positioning portion 122. In some examples, the positioning portion 122 may be hollow cylindrical. In this case, the other end of the first drive mechanism 30 may be fitted onto or embedded in the positioning portion 122. In some examples, the positioning portion 122 may consist of at least two arc-shaped columns.

[0286] Furthermore, the application device 1000 disclosed herein is not limited thereto. In some examples, the application device 1000 may not include the first drive mechanism 30. In this case, when the moving body 200 is released, the moving body 200 can also be moved toward the proximal end by manually applying an action to the moving body 200.

[0287] In some examples, referring to FIG13, the moving body 200 may include a first locking part 236 configured to releasably interlock with the first holding part 130. Thus, the moving body 200 can be releasably held in the first holding part 130 by the cooperation of the first locking part 236 with the first holding part 130.

[0288] In some examples, the first locking part 236 may be provided on the side wall 230 of the moving body 200. That is, the first locking part 236 may be provided on the side wall 230 of the moving body 200. The first locking part 236 may cooperate with the first retaining part 130 to retain the moving body 200 in the first housing 100.

[0289] In some examples, the number of first locking portions 236 can be one or more, such as 1, 2, 3, or 4. In some examples, the number of first locking portions 236 can be the same as the number of first retaining portions 130. In the embodiment shown in FIG13, the number of first locking portions 236 is 1.

[0290] In some examples, if there are multiple first holding parts 130, there are also multiple first locking parts 236. On the projection along the central axis CA, the positions of the multiple first locking parts 236 may be the same as the positions of the multiple first holding parts 130.

[0291] In some examples, the first locking portion 236 can be formed as a snap fastener. Specifically, the first locking portion 236 can have a proximal surface, to which the first retaining portion 130 can retain the moving body 200 by overlapping, abutting, or engaging, and to which the first retaining portion 130 can release the moving body 200 by moving away from the surface (see Figures 14A and 14B). That is, the first retaining portion 130 and the first locking portion 236 can be formed as an interlocking structure, with the projections of the first retaining portion 130 and the first locking portion 236 overlapping in the direction along the central axis CA. The first retaining portion 130 retains the first locking portion 236 through this overlapping portion, and the first retaining portion 130 and / or the first locking portion 236 can move away from each other to eliminate the overlapping portion, thereby releasing the first locking portion 236. In some examples, the first retaining part 130 and / or the first locking part 236 can be actuated in a manner that is opposite to each other, thereby releasing the first locking part 236 from the first retaining part 130.

[0292] In some examples, the first locking portion 236 may be approximately parallel to or away from the central axis CA in the direction from the proximal end to the distal end. In this case, the first locking portion 236 may be closer to the central axis CA than the first retaining portion 130, thereby facilitating interlocking with the inwardly retracting first retaining portion 130.

[0293] In other examples, the first locking portion 236 may be approximately parallel to or toward the central axis CA in the direction from the proximal end to the distal end. In this case, the first locking portion 236 may be further away from the central axis CA than the first retaining portion 130, thereby facilitating interlocking with the outwardly distributed first retaining portion 130.

[0294] In some examples, the first locking portion 236 may be formed in such a way that it is recessed from the outer surface of the sidewall 230 toward the central axis CA. In some examples, the first locking portion 236 may be formed as a hollow structure, for example, a through hole extending through the sidewall 230 in a direction approximately orthogonal to the central axis CA. In some examples, a notch communicating with the first locking portion 236 may be formed in the moving body 200, and the actuating portion 504 may be arranged at the distal end through the notch.

[0295] In some examples, the first locking portion 236 may also be formed such that the periphery of the first bottom 210 protrudes from the sidewall 230 along a direction orthogonal to the central axis CA, in which case the first bottom 210 and the sidewall 230 may be fixedly connected. In other examples, the first locking portion 236 may also be in the form of an inverted hook or an L-shape.

[0296] The examples disclosed herein are not limited thereto. As described above, the concept of the present invention is to form a fastener, hook, latch, or pin structure between the first retaining portion 130 and the first locking portion 236 for interlocking. In this case, the first locking portion 236 may have a surface facing the proximal end of the applying device 1000, and the first retaining portion 130 retains the first locking portion 236 by engaging the proximal end surface of the first retaining portion 130 with the distal end surface of the first retaining portion 130, and the first retaining portion 130 releases the first locking portion 236 by separating the proximal end surface of the first locking portion 236 from the distal end surface of the first retaining portion 130.

[0297] In some examples, referring to Figures 14A and 14B, the first holding portion 130 can be formed in an L-shape, and the first locking portion 236 can be formed as a hollow structure disposed on the side wall 230. When the moving body 200 is held, as shown in Figure 14A, the protrusion 134 of the first holding portion 130 is located within the hollow structure of the first locking portion 236, thereby supporting the moving body 200 and holding it. When the moving body 200 is released, as shown in Figure 14B, the arm 132 of the first holding portion 130 pivots in a direction away from the central axis CA, causing the protrusion 134 to move away from the central axis CA. The protrusion 134 leaves the hollow structure of the first locking portion 236, thereby releasing the moving body 200. Under the action of the first drive mechanism 30, the moving body 200 moves towards the proximal end.

[0298] Additionally, in some examples, the application device 1000 may also include a first triggering mechanism 50 configured to separate the first holding portion 130 from the first locking portion 236 to release the moving body 200 (see Figures 12A, 12C, 14A, or 14B). Thus, the moving body 200 can be conveniently released via the first triggering mechanism 50.

[0299] In some examples, the application device 1000 may include a triggering mechanism for triggering the housing 10 to release the moving body 200. In some examples, the application device 1000 may include a triggering mechanism for triggering the first housing 100 to release the moving body 200. In this disclosure, this triggering mechanism may also be referred to as a push triggering mechanism. Specifically, in some examples, the application device 1000 may further include a first triggering mechanism 50. The first triggering mechanism 50 is configured to trigger a first holding portion 130 to release the moving body 200 by the first holding portion 130. In some examples, the first triggering mechanism 50 may be configured to actuate the first holding portion 130 and / or the first locking portion 236 in a manner that moves them away from each other to release the moving body 200. For example, the first triggering mechanism 50 may be configured to actuate the first holding portion 130 to move away from the central axis CA to release the holding of the first locking portion 236, thereby releasing the moving body 200. In other words, the first triggering mechanism 50 can be configured to actuate the first holding part 130 and / or the first locking part 236 so that the two are moved away from each other, thereby releasing the first locking part 236.

[0300] In some examples, the number of first triggering mechanisms 50 can be one or more. For example, the number of first triggering mechanisms 50 can be 1, 2, 3, or 4, etc. In some examples, the number of first holding parts 130 can be one or more. For example, the number of first holding parts 130 can be 1, 2, 3, or 4, etc. In some examples, the number of first holding parts 130 can be the same as the number of first triggering mechanisms 50.

[0301] In some examples, the number of first locking parts 236 can be one or more. For example, the number of first locking parts 236 can be 1, 2, 3 or 4, etc. In some examples, the number of first locking parts 236 can be the same as the number of first holding parts 130.

[0302] In some examples, multiple first trigger mechanisms 50 can be symmetrically arranged. For example, when the number of first trigger mechanisms 50 is two, the two first trigger mechanisms 50 can be symmetrically arranged. In some examples, the number of notches 290 can be two. In some examples, the two notches 290 can be symmetrically arranged. In some examples, when the number of first trigger mechanisms 50 is two, the moving body 200 may not have the first marking portion 239, and the support 280 may not have the second marking portion 281, because the support 280 can then have a symmetrical structure, eliminating the need for identification of the assembly direction with the moving body 200.

[0303] In some examples, the first triggering mechanism 50 may include a pressing part 502 and an actuating part 504 (see Figures 14A and 14B). That is, the push triggering mechanism may include a pressing part 502 and an actuating part 504. In some examples, the first triggering mechanism 50 may include a pressing part 502 that can be pressed during operation, and an actuating part 504 configured to be linked with the pressing part 502 and capable of actuating the first holding part 130.

[0304] In some examples, the first triggering mechanism 50 may be mounted on the distal end 120. In some examples, the first triggering mechanism 50 may be formed on the distal end 120. In some examples, applying an action to the pressing part 502 may cause the actuating part 504 to actuate the first holding part 130, thereby releasing the first holding part 130 from holding the moving body 200 and thus releasing the moving body 200. In some examples, applying an action to the pressing part 502 may cause the actuating part 504 to actuate the first holding part 130 or the first locking part 236 to separate the two and thus release the moving body 200. That is, in some examples, applying an action to the pressing part 502 may cause the actuating part 504 to actuate the first holding part 130 or the first locking part 236 to separate the two and release the first housing 100 from holding the moving body.

[0305] In some examples, the actuating part 504 may be configured to apply an action to the first retaining part 130 in a direction substantially orthogonal to the central axis CA of the applying device. In this case, when the actuating part 504 is driven, the first retaining part 130 can be actuated away from or closer to the central axis CA, thereby enabling the first retaining part 130 to unlock from the locked component (e.g., the first locking part 236) in a manner away from or closer to the central axis CA.

[0306] In some examples, the actuating part 504 may extend along a direction having a preset angle with the central axis CA. In some examples, the preset angle may not be zero. In this case, when the actuating part 504 is applied at an appropriate angle, the actuating part 504 can apply an action to the first holding part 130 in a direction orthogonal to the central axis CA of the applying device to actuate the first holding part 130.

[0307] In some examples, the actuator 504 can be acted upon along its extending direction to actuate the first holding part 130. For example, when the preset angle is 90 degrees, the actuator 504 can be acted upon in a direction orthogonal to the central axis CA to actuate the first holding part 130. Thus, the actuator 504 can actuate the first holding part 130 to release the first locking part 236 by moving it closer to or further away from the central axis CA.

[0308] In some examples, when the preset included angle is between 0 and 90 degrees or between 90 and 180 degrees, such as preset included angles of 20, 30, 40, 45, 60, 70, 80, 100, 120, 130, 135, 150, 160, or 170 degrees, the action applied to the actuator 504 along its extension direction can be decomposed into an action parallel to the central axis CA and an action orthogonal to the central axis CA. Thus, by acting orthogonally to the central axis CA, the first holding part 130 can be actuated to release the first locking part 236 by moving closer to or further away from the central axis CA.

[0309] In some examples, the actuator 504 may extend along a direction having a predetermined angle with the central axis CA and toward the distal end. This allows for easy application of action to the actuator 504 from the distal end.

[0310] In some examples, the actuating part 504 can be acted upon along the direction of the central axis of the applying device 1000 to actuate the first holding part 130. In some examples, when the actuating part 504 is acted upon along the direction of the central axis CA, the actuating part 504 can act upon the first holding part 130 in a direction orthogonal to the central axis CA.

[0311] In some examples, the actuating part 504 may be coupled to the first retaining part 130. In some examples, in response to the application of an action to the actuating part 504, the first retaining part 130 may be driven to swing away from or towards the central axis CA of the application device 1000 with the connection position of the first retaining part 130 and the distal end 120 as the fulcrum.

[0312] In some examples, the actuating part 504 can be acted upon along the central axis CA of the applying device 1000. In this case, the first holding part 130 and the actuating part 504 can form a lever system as a whole, with the connection point of the first holding part 130 and the distal end 120 as the fulcrum. When the actuating part 504 is driven by an action along the central axis CA, a torque can be generated to actuate the first holding part 130 to swing along the direction close to or away from the central axis CA with the aforementioned connection point as the fulcrum. As a result, the first holding part 130 can release the first locking part 236 in a manner that moves close to or away from the central axis CA.

[0313] In some examples, referring to Figure 12E, the first triggering mechanism 50 may have a rib 51. In some examples, the rib 51 may be formed on the actuating portion 504. Thus, when an action is applied to the first triggering mechanism 50, the risk of breakage of the actuating portion 504 can be reduced.

[0314] In some examples, the actuating part 504 may be connected to the proximal side of the first holding part 130. In some examples, the actuating part 504 may be connected to the arm 134 of the first holding part 130. In some examples, the actuating part 504 may be connected to the proximal side of the arm of the first holding part 130. This facilitates actuation of the first holding part 130.

[0315] In some examples, the distal end 120 may have a through structure. In some examples, the actuating part 504 may be connected to the first retaining part 130 and extend to the through structure in a predetermined direction. The predetermined direction may refer to a direction having a predetermined angle with the central axis CA. Thus, the actuating part 504 can be acted upon through the through structure, improving operational convenience. In some examples, the through structure may be an opening formed in the distal end 120.

[0316] In some examples, the actuating part 504 and the first retaining part 130 can be integrally formed. In this case, the overall rigidity and stability of the actuating part 504 and the first retaining part 130 can be improved, which is suitable for transmitting the torque that can drive the first retaining part 130 to swing.

[0317] In some examples, the end of the actuating part 504 near the first holding part 130 may have a curved structure. In this case, the lever arm length of the first holding part 130 and the actuating part 504 as a whole can be increased, thereby generating a torque sufficient to actuate the first holding part 130 to swing with a small force. In other words, a small force can be applied to the actuating part 504 to actuate the first holding part 130. In addition, the curved structure can serve as a support point to improve the overall stability of the first holding part 130 and the actuating part 504; furthermore, the curved structure can change the direction of the force applied to the actuating part 504, so that the force applied to the actuating part 504 can be effectively transmitted to the first holding part 130 and actuate the first holding part 130 to swing in a direction close to or away from the central axis CA.

[0318] In some examples, when the effect applied to the first trigger mechanism 50 disappears, the first trigger mechanism 50 and the first holding part 130 can return to their initial positions.

[0319] As described above, applying an action to the pressing part 502 can actuate the first holding part 130 by the actuating part 504. In some examples, the pressing part 502 may be connected to the actuating part 504.

[0320] In some examples, the pressing part 502 and the actuating part 504 can be integrally formed. This simplifies the structural design of the first triggering mechanism 50 and improves its stability.

[0321] In some examples, the pressing part 502 may be located at the distal end 120. In some examples, the pressing part may be located in a through structure at the distal end 120. Thus, the first holding part 130 can release the first locking part 236 by a simple operation.

[0322] In some examples, the pressing portion 502 may be generally disc-shaped. In some examples, the pressing portion 502 may be generally frustum-shaped. In some examples, the pressing portion 502 may be generally flush with the end portion 120. In some examples, the pressing portion 502 may extend through the end portion 120.

[0323] In some examples, the pressing part 502 may be located on the periphery of the housing.

[0324] In some examples, the application device 1000 may also include a gasket 60 fitted to and covering the through structure (see FIG11A). In some examples, the first trigger mechanism 50 can be driven by applying an action at the location of the gasket 60.

[0325] In some examples, the shape of the gasket 60 may be similar to or the same as the shape of the housing 10. For example, referring to Figure 11A, when the housing 10 is cylindrical, the gasket 60 may be teardrop-shaped. As another example, referring to Figure 5C, when the housing 10 is elliptical, the gasket 60 may be elliptical.

[0326] In some examples, see Figure 11A, the upper surface of the gasket 60 may have multiple ring-shaped pleats. This allows the gasket 60 to be easily pressed and deformed.

[0327] In some examples, referring to Figure 11B, the upper surface of the pad 60 may have multiple dot-like protrusions. This increases the roughness of the upper surface of the pad 60, thereby helping to prevent slippage during pressing.

[0328] In some examples, the gasket 60 may have a gasket positioning portion 61 (see FIG11C). In some examples, the gasket positioning portion 61 may be disposed on the side of the gasket 60 near the first trigger mechanism 50.

[0329] In some examples, the gasket positioning portion 61 may be annular (see FIG. 11C). In some examples, when the gasket 60 is assembled in a through structure, the gasket positioning portion 61 may surround the first trigger mechanism 50. In this case, by having the gasket positioning portion 61 surround the first trigger mechanism 50, the positional offset of the gasket 60 can be reduced, thereby facilitating the user to accurately apply an action to the gasket 60 to drive the first trigger mechanism 50.

[0330] In some examples, the first triggering mechanism 50, the first holding part 130, and the housing can be integrally formed. This simplifies the overall structural design of the application device.

[0331] In some examples, as described above, the actuating part 504 of the first triggering mechanism 50 can actuate the first holding part 130 to release the first holding part 130 from holding the moving body 200, thereby releasing the moving body 200.

[0332] In some examples, the actuating portion 504 may be formed as a structure extending from the pressing portion 502 toward the first retaining portion 130 (see FIG. 14A). In some examples, the number of actuating portions 504 may be one or more, such as 1, 2, 3, or 4. In some examples, the number of actuating portions 504 may be the same as the number of first retaining portions 130.

[0333] As described above, the first holding portion 130 can be parallel to the central axis CA in the direction toward the proximal end. The actuating portion 504 is configured to actuate the first holding portion 130 so that the end of the first holding portion 130 near the proximal end moves away from the central axis CA, thereby releasing the holding of the moving body 200.

[0334] Before the actuating part 504 actuates the first holding part 130, the first holding part 130 interlocks with the first locking part 236 to hold the moving body 200 (see FIG. 14A). When the actuating part 504 actuates the first holding part 130 (for example, by pressing the pressing part 502 in the direction towards the proximal end), under the actuation action of the actuating part 504, the first holding part swings in a direction away from the central axis CA, so that the protrusion 134 of the first holding part 130 disengages from the first locking part 236, thereby releasing the interlock between the first holding part 130 and the first locking part 236, thereby releasing the moving body 200 (see FIG. 14B).

[0335] In some examples, the second housing 140 may include a first defining mechanism 150 and a second defining mechanism 170 (see FIG. 15A). In some examples, the first defining mechanism 150 and the second defining mechanism 170 may be in communication with each other. In some examples, the first defining mechanism 150 and the second defining mechanism 170 may be hollow cylindrical structures. In some examples, the first defining mechanism 150 may releasably hold the moving body 200 and may define the movement path of the moving body 200. In some examples, the second defining mechanism 170 may define the receiving position of the medical device 800.

[0336] In some examples, referring to FIG12B, the first housing 100 may have a third retaining portion 124. In some examples, referring to FIG15B, the second housing 140 may have a third locking portion 142. In some examples, the third retaining portion 124 may be coupled to the third locking portion 142. In some examples, the third retaining portion 124 may be releasably interlocked with the third locking portion 142 by at least one of a latch, hook, latch, or pin.

[0337] In some examples, during the assembly of the first housing 100 and the second housing 140, the third retaining part 124 may be aligned with the third locking part 142.

[0338] In some examples, the number of third retaining parts 124 can be one or more, such as 1, 2, 3, or 4. In some examples, if there are multiple third retaining parts 124, the multiple third retaining parts 124 can be symmetrically arranged on the inner wall of the first housing 100.

[0339] In some examples, the number of third locking parts 142 can be one or more, such as 1, 2, 3, or 4. In some examples, if there are multiple third locking parts 142, the multiple third locking parts 142 can be symmetrically arranged on the periphery of the second housing 140.

[0340] In some examples, referring to FIG. 12D, the first housing 100 may have a fourth retaining portion 1241. In some examples, referring to FIG. 15D, the second housing 140 may have a fourth locking portion 1421. In some examples, the fourth retaining portion 1241 may be coupled to the fourth locking portion 1421. This helps to prevent the second housing 140 from disengaging from the first housing 100. In some examples, the fourth retaining portion 1241 may be releasably interlocked with the fourth locking portion 1421 by at least one of a latch, hook, latch, or pin.

[0341] In some examples, during the assembly of the first housing 100 and the second housing 140, the fourth retaining part 1241 may be aligned with the fourth locking part 1421.

[0342] In some examples, the number of fourth retaining parts 1241 can be one or more, such as 1, 2, 3, or 4. In some examples, if there are multiple fourth retaining parts 1241, the multiple fourth retaining parts 1241 can be symmetrically arranged on the inner wall of the first housing 100.

[0343] In some examples, the number of fourth locking parts 1421 can be one or more, such as 1, 2, 3, or 4. In some examples, if there are multiple fourth locking parts 1421, the multiple fourth locking parts 1421 can be symmetrically arranged on the periphery of the second housing 140.

[0344] In some examples, referring to FIG12B, the first housing 100 may have a third marking portion 125. In some examples, referring to FIG15B, the second housing 140 may have a fourth marking portion 143. In some examples, during the assembly of the first housing 100 and the second housing 140, the third marking portion 125 may be aligned with the fourth marking portion 143.

[0345] In some examples, the third marking portion 125 may be coupled to the fourth marking portion 143. In some examples, the coupling between the third marking portion 125 and the fourth marking portion 143 may be a male-female mating mechanism. For example, the shape of the third marking portion 125 may be a groove, and the shape of the fourth marking portion 143 may be a protrusion.

[0346] In some examples, the third marking portion 125 may abut against the fourth marking portion 143 in the circumferential direction of the housing 10. This can suppress undesirable relative rotation between the first housing 100 and the second housing 140.

[0347] In some examples, the number of third identifier parts 125 can be one or more. For example, the number of third identifier parts 125 can be one, two, three, or four. In some examples, the number of fourth identifier parts 143 can be one or more. For example, the number of fourth identifier parts 143 can be one, two, three, or four. In some examples, the number of third identifier parts 125 and the number of fourth identifier parts 143 can be the same.

[0348] In some examples, during the assembly of the first housing 100 and the second housing 140, the third retaining portion 124 and the third locking portion 142 can be aligned by aligning the third marking portion 125 with the fourth marking portion 143. This facilitates the alignment of the third retaining portion 124 and the third locking portion 142 during assembly.

[0349] In some examples, in the application device 1000 according to this disclosure, the housing 10 may include a first outer shell 100 having a first holding portion 130 and a second outer shell 140 fitable to the first outer shell 100. The second outer shell 140 may have a first limiting mechanism 150 and a second limiting mechanism 170 communicating with each other. The second limiting mechanism 170 may be configured to define the receiving position of the medical device 800. The auxiliary mechanism 20 may be fitted to the first limiting mechanism 150 and movable along the first limiting mechanism 150 when the moving body 200 is released by the first holding portion 130. In this case, the movement of the moving body 200 is defined by the first limiting mechanism 150 of the second outer shell 140, and the receiving position of the medical device 800 is defined by the second limiting mechanism 170 of the second outer shell 140, thereby facilitating more accurate application of the medical device 800 to the host.

[0350] In some examples, the first limiting mechanism 150 may have a limiting portion 151 (see FIG. 15B). The limiting portion 151 may restrict the moving body 200, thereby preventing undesirable rotation of the moving body 200. In some examples, the limiting portion 151 may be a groove and / or a ridge. In some examples, the limiting portion 151 may include a ridge 154 disposed on the inner wall of the first limiting mechanism 150 and extending generally along the central axis CA. In some examples, the limiting portion 151 may also include a groove 152 disposed on the inner wall of the first limiting mechanism 150 and extending generally along the central axis CA. In some examples, the length of the ridge 154 and the groove 152 may be less than the height of the first limiting mechanism 150, and the ridge 154 and the groove 152 may be generally collinear in the direction of the central axis CA.

[0351] In some examples, the number of limiting portions 151 can be one or more, such as 1, 2, 3, or 4. In some examples, multiple limiting portions 151 can be evenly distributed on the sidewall of the first limiting mechanism 150.

[0352] In some examples, the ridge 154 of the limiting portion 151 can engage with the limiting portion 232 of the moving body 200, which includes a groove structure, thereby preventing undesirable rotation of the moving body 200. In some examples, the moving body 200 can be assembled to the first limiting mechanism 150 along the groove 152. Thus, the groove 152 can provide a guiding effect during assembly.

[0353] In some examples, the limiting portion 151 may also include a slot 156 provided on the first limiting mechanism 150 (see FIG. 15B). In some examples, the slot 156 may be used to provide engagement space for the protrusion 234 of the moving body 200.

[0354] In some examples, the slot 156 can also be configured to expose the first locking portion 236 when the moving body 200 is held in the first holding portion 130. In this case, the first holding portion 130 can hold the first locking portion 236 through the slot 156; in addition, by forming the slot 156 for exposing the first locking portion 236 in the first limiting mechanism 150, sufficient movement stroke can be provided for the moving body 200 with a smaller spatial structure, which is beneficial to improving the integration of the application device.

[0355] In some examples, the first defining mechanism 150 may further include reinforcing ribs 158 disposed on its inner wall (see Figure 15B). In some examples, the reinforcing ribs 158 may extend generally along the direction of the central axis CA. In some examples, the number of reinforcing ribs 158 may be multiple, such as 2, 3, 4, 6, etc. In some examples, the reinforcing ribs 158 may be evenly distributed on the inner wall of the first defining mechanism 150. In some examples, the reinforcing ribs 158 may provide line contact when the moving body moves relative to the first housing.

[0356] In some examples, the first limiting mechanism 150 can restrict the travel of the moving body 200 in the direction along the central axis CA. In this case, by limiting the travel of the moving body 200 in the direction along the central axis CA by the first limiting mechanism 150, the medical device 800 housed in the receiving portion 250 can be pushed a predetermined distance more accurately, thereby enabling the medical device 800 to be applied to the host more accurately.

[0357] Additionally, in some examples, when projected along the central axis CA, the receiving portion 250 may at least partially coincide with the wall of the first limiting mechanism 150, and the distal end of the moving body 200 may at least partially coincide with the wall of the first limiting mechanism 150 (see FIG. 14A). In this case, by making the receiving portion 250 and the moving body 200 at least partially coincide with the wall of the first limiting mechanism 150, the travel distance of the moving body 200 along the first limiting mechanism 150 can be effectively limited with a simplified structure.

[0358] Additionally, in some examples, a protrusion is provided on the distal end of the moving body 200, protruding in a direction generally orthogonal to the central axis CA and away from the central axis CA. In this case, the protrusion forms a latch with the wall of the first limiting mechanism 150, thereby effectively limiting the excessive travel of the moving body 200 toward the proximal end.

[0359] As described above, the auxiliary mechanism may include a positioning part 212 for positioning the first drive mechanism 30. In some examples, the positioning part 212 may be disposed on the side of the receiving part 250 facing the distal end.

[0360] In some examples, the second limiting mechanism 170 may have an opening slot 141 through which the positioning part 212 extends. In some examples, the opening slot 141 may extend from the second limiting mechanism 170 to the first limiting mechanism 150. In this case, the movement stroke of the moving body 200 along the central axis CA can be further limited by the cooperation of the positioning part 212 and the moving body 200.

[0361] In some examples, the number of openings 141 can be the same as the number of support frames for the positioning part 212. Thus, the positioning part 212 can extend through the second housing 140 to abut against the first drive mechanism 30.

[0362] Additionally, in some examples, the first limiting mechanism 150 can suppress the rotation of the moving body 200. In this case, by suppressing the rotation of the moving body 200, it is possible to prevent undesirable rotation of the puncture member 260 during application.

[0363] Additionally, in some examples, the first defining mechanism 150 may include grooves and / or ridges that are continuously or discontinuously disposed on the inner wall, generally along the direction of the central axis CA. In this case, by engaging the moving body 200 with the grooves and / or ridges of the first defining mechanism 150, undesirable rotation of the moving body 200 within the first defining mechanism 150 can be effectively suppressed.

[0364] Additionally, in some examples, the moving body 200 may include a groove and / or ridge disposed on the outer wall of the side wall 230 generally along the direction of the central axis CA. In this case, by engaging the groove and / or ridge of the moving body 200 with the groove and / or ridge of the first defining mechanism 150, undesirable rotation of the moving body 200 within the first defining mechanism 150 can be effectively suppressed.

[0365] Additionally, in some examples, the first limiting mechanism 150 and the second limiting mechanism 170 may be hollow cylindrical, and the inner diameter of the first limiting mechanism 150 may not be greater than the inner diameter of the second limiting mechanism 170. In this case, by setting the first limiting mechanism 150 and the second limiting mechanism 170 to hollow cylindrical shapes, it is convenient for the auxiliary mechanism 20 to move along the first limiting mechanism 150 and the second limiting mechanism 170.

[0366] Additionally, in some examples, when the moving body 200 is released, the moving body 200 can move along the first limiting mechanism 150 and the receiving portion 250 can move along the second limiting mechanism 170. In this case, by moving the moving body 200 along the first limiting mechanism 150 and the receiving portion 250 along the second limiting mechanism 170, the medical device 800 housed in the receiving portion 250 can be applied more accurately to the desired location on the host's body surface.

[0367] In some examples, a limiting portion 232 may be provided on the side wall 230 of the moving body 200 (see FIG15B). The limiting portion 232 may cooperate with the limiting portion 151 of the first limiting mechanism 150 to suppress undesirable rotation of the moving body 200.

[0368] In some examples, the restricted portion 232 may include a groove 235 formed on the outer wall of the sidewall 230. In some examples, the groove 235 may be formed between two side-by-side ridges. In some examples, the restricted portion 232 may also include an arm 233 formed by the sidewall 230 extending distally along the direction of the groove 235. In some examples, the restricted portion 232 may also include a protrusion 234 projecting from the arm 233 along a direction generally orthogonal to the central axis CA and away from the central axis CA. In some examples, the number of restricted portions 232 may be one or more, such as 1, 2, 3, or 4. In some examples, the number of restricted portions 232 may be the same as the number of restrictive portions 151. In some examples, the multiple restricted portions 232 may be evenly distributed on the sidewall 230. In some examples, the arm 233 may be elastic.

[0369] In some examples, when projected along a direction approximately orthogonal to the central axis CA, the projection surface of the protrusion 234 of the restricted portion 232 can be further away from the central axis CA than the projection of the slot 156 of the restricting portion 151. Furthermore, the projection of the ridge 154 can substantially align with the projection of the slot 235. Additionally, the projection of the protrusion 234 can substantially align with the projection of the slot 152. In some examples, the length and / or width of the receiving portion 250 can be greater than the diameter of the first limiting mechanism 150.

[0370] In some examples, the sidewall 230 of the moving body 200 may have a moving body limiting portion 238 (described later). The moving body limiting portion 238 can restrict the puncture member 260 disposed within the moving body 200, thereby preventing undesirable rotation of the puncture member 260. In some examples, the moving body limiting portion 238 may be formed as a groove and / or a ridge. In some examples, the moving body limiting portion 238 may be two ridges arranged side by side and a groove located between the two ridges.

[0371] In some examples, referring to FIG15C, the second housing 140 may include a magnet receiving portion 252. As described above, the application device 1000 may include a magnet. In some examples, the magnet receiving portion 252 may be configured to receive a magnet.

[0372] In some examples, the auxiliary mechanism 20 may have a passage 254 through which the magnet receiving portion 252 extends. In some examples, the magnet receiving portion 252 may pass through the passage 254 during the assembly of the auxiliary mechanism 20 into the second housing 140.

[0373] In some examples, the passage 254 may be provided on the side of the auxiliary mechanism 20 that has the receiving portion 250. In this case, by bringing the passage 254 closer to the receiving portion 250, when the medical device 800 has not yet been applied to the host (i.e., when the auxiliary mechanism 20 is assembled to the second housing 140), the magnet housed in the passage 254 can be brought closer to the medical device 800 housed in the receiving portion 250, thereby helping to keep the switching module 884 of the electronic device 880 in the off state.

[0374] In some examples, see Figure 15A or Figure 15D, the second defining mechanism 170 may have a profile that matches the portion of the first housing 100 near its proximal end.

[0375] In some examples, the second limiting mechanism 170 may have a surface 171 that mates with the first housing 100. In some examples, the fourth locking portion 1421 may be disposed on the surface 171. In some examples, the surface 171 may be a plane (see FIG. 15D).

[0376] In some examples, referring to Figure 15D, the second limiting mechanism 170 may have an outwardly protruding arcuate structure 172. In this case, space for movement of the cap 700 can be provided during the relative twisting of the housing 10 and the cap 700.

[0377] In some examples, the arcuate structure 172 may be formed on the surface 171. In some examples, the arcuate structure 172 may protrude from the surface 171.

[0378] In some examples, the first housing 100 may have a first limiting structure 111 (see FIG. 12D). When the first housing 100 is assembled with the second housing 140, one end of the first limiting structure 111 may abut against the arcuate structure 172. In some examples, the first limiting structure 111 may abut against the arcuate structure 172 from above. This helps to limit the relative orientation of the first housing 100 and the second housing 140 after assembly.

[0379] As described above, the third retaining portion 124 can be coupled to the third locking portion 142. In some examples, when the third retaining portion 124 is coupled to the third locking portion 142, the second housing 140 can be restricted to move in a direction away from the first housing 100. In some examples, the first housing 100 and the second housing 140 can be fixedly assembled by coupling the third retaining portion 124 to the third locking portion 142 and abutting the first limiting structure 111 against the arcuate structure 172.

[0380] In some examples, referring to Figure 12D, the first housing 100 may also have a second confinement structure 112. In some examples, referring to Figure 15D, the second housing 140 may also have a confinement structure 173.

[0381] In some examples, after the first housing 100 and the second housing 140 are assembled, the second restraining structure 112 and the restraining structure 173 can abut against each other in the circumferential direction. This helps to prevent the first housing 100 and the second housing 140 from rotating in the circumferential direction.

[0382] In some examples, the second limiting structure 112 may be configured to guide the second housing 140 into the first housing 100. The second limiting structure 112 may extend along a predetermined assembly direction of the first housing 100 and the second housing 140. In this case, assembling the first housing 100 and the second housing 140 in such a manner that the limiting structure 173 moves along the second limiting structure 112 can help to assemble the first housing 100 and the second housing 140 in the correct orientation.

[0383] In some examples, referring to FIG15D, the first engagement feature 191 may be disposed on the second housing 140. In some examples, the first engagement feature 191 may be formed at the proximal end of the second housing 140. This facilitates coupling of the housing 10 and the cap 700.

[0384] Embodiments of this disclosure include:

[0385] B. An instrument kit for applying a medical device, the instrument kit comprising an application device for applying the medical device to a host, the application device including a housing and an auxiliary mechanism, the housing including a proximal end that is close to the host during operation and a distal end that is distant from the host, the auxiliary mechanism releasably holding the medical device and movable relative to the housing when released, the auxiliary mechanism being configured to be driven in a direction toward the proximal end when released to place the medical device at least partially under the skin of the host.

[0386] In some examples, Embodiment B may be combined with any one or more of the following additional elements. Element 1: The auxiliary mechanism includes a motion body releasably held in the housing and configured to be movable relative to the housing when released, and a receiving portion disposed in the motion body and configured to receive and accommodate the medical device. Element 2: The housing includes a first retaining portion configured to releasably hold the motion body, and the motion body includes a first locking portion configured to releasably interlock with the first retaining portion. Element 3: The application device further includes a first triggering mechanism configured to disengage the first retaining portion from the first locking portion to release the motion body. Element 4: It also includes a sharp object and a support configured to support the sharp object and fitted to the motion body, wherein when the motion body is released, the motion body is driven toward the proximal end and, through the sharp object, places the medical device at least partially under the skin of the host.

[0387] Element 5: The application device further includes a first drive mechanism configured to apply an action to the auxiliary device in a manner toward the proximal end and to drive the motion body toward the host when the auxiliary device is released. Element 6: The housing includes a first outer shell having the first retaining portion and a second outer shell fitable to the first outer shell, the second outer shell having a first limiting mechanism and a second limiting mechanism in communication with each other, the auxiliary mechanism being fitted to the first limiting mechanism and movable along the first limiting mechanism when the motion body is released by the first retaining portion. Element 7: The first retaining portion has a surface facing the distal end, and the first locking portion has a surface facing the proximal end; when the motion body is held, the surface of the first retaining portion facing the distal end engages with the surface of the first locking portion facing the proximal end; when the motion body is released, the surface of the first retaining portion facing the distal end separates from the surface of the first locking portion facing the proximal end. Element 8: The first retaining portion has an arm extending generally along the central axis of the application device, and a protrusion linked to the arm and projecting generally along a direction orthogonal to the central axis of the application device. Element 9: The arm of the first retaining portion is elastic in a direction substantially orthogonal to the central axis of the application device. Element 10: The arm of the first retaining portion is pivotable or swingable toward or away from the central axis of the application device. Element 11: The arm of the first retaining portion approaches the central axis of the application device in a direction from the distal end to the proximal end, and the protrusion of the first retaining portion protrudes toward the central axis of the application device. Element 12: The arm of the first retaining portion moves away from the central axis of the application device in a direction from the distal end to the proximal end, and the protrusion of the first retaining portion protrudes away from the central axis of the application device. Element 13: The first locking portion moves away from or substantially parallel to the central axis of the application device in a direction from the proximal end to the distal end. Element 14: The first locking portion approaches or substantially parallel to the central axis of the application device in a direction from the proximal end to the distal end. Element 15: The first housing includes a hollow cylindrical periphery and a distal end disposed near one end of the periphery, wherein the first retaining portion is disposed at the distal end.

[0388] Element 16: The first housing further includes a first limiting portion extending generally along the central axis of the application device, the first limiting portion being configured to maintain the balance of the moving body in a plane orthogonal to the central axis of the application device. Element 17: The first limiting portion is disposed at the distal end, and the first retaining portion, the first limiting portion, and the first housing are integrally formed. Element 18: The first triggering mechanism includes a pressing portion that can be pressed during operation, and an actuating portion configured to be linked with the pressing portion and actuate the first retaining portion. Element 19: The actuating portion extends along a direction having a predetermined angle with the central axis of the application device. Element 20: The actuating portion extends along a direction having a predetermined angle with the central axis of the application device and toward the distal end.

[0389] Element 21: The first retaining portion is actuated in response to an action applied to the actuating portion along its extension direction. Element 22: The first retaining portion is actuated in response to an action applied to the actuating portion along the central axis of the application device. Element 23: The actuating portion is connected to the first retaining portion. Element 24: The actuating portion and the first retaining portion are integrally formed. Element 25: The first retaining portion is driven to swing away from or towards the central axis of the application device with the connection point between the first retaining portion and the distal end portion as a fulcrum in response to an action applied to the actuating portion. Element 26: The distal end portion has a through structure, and the actuating portion is connected to the first retaining portion and extends to the through structure in a predetermined direction. Element 27: The end of the actuating portion near the first retaining portion has a curved structure. Element 28: The pressing portion is located in the through structure. Element 29: The first triggering mechanism, the first retaining portion, and the first housing are integrally formed. Element 30: The first triggering portion is configured to be actuated along the central axis of the application device. Element 31: When the moving body is released, the moving body is movable along the first limiting mechanism and the receiving portion is movable along the second limiting mechanism. Element 32: The first limiting mechanism restricts the travel of the moving body in the direction along the central axis of the application device. Element 33: Projected along the central axis of the application device, the receiving portion at least partially coincides with the wall of the first limiting mechanism, and the end of the moving body near the distal end at least partially coincides with the wall of the first limiting mechanism. Element 34: The first triggering mechanism and the first holding mechanism are integrally formed in the housing.

[0390] In some examples, embodiment B, and embodiments combining embodiment B with any one or more of the corresponding elements 1 to 34, can be combined with embodiment A or a combination of embodiment A and its corresponding elements.

[0391] Figure 16A is an exploded view from a first perspective showing the moving body 200, the second drive mechanism 40, and the puncture member 260 involved in the present disclosure example; Figure 16B is an exploded view from a second perspective showing the moving body 200, the second drive mechanism 40, and the puncture member 260 involved in the present disclosure example; Figure 17A is a cross-sectional view showing the puncture member 260 involved in the present disclosure example when it is held; Figure 17B is a cross-sectional view showing the puncture member 260 involved in the present disclosure example when it is released.

[0392] In some examples, the moving body 200 and the puncture member 260 may be integrally fixedly connected. In other examples, the moving body 200 and the puncture member 260 may be detachably assembled and coupled. In some examples, the puncture member 260 may be releasably held by the moving body 200.

[0393] In some examples, as described above, the moving body 200 may have a first bottom 210 near its distal end, a second bottom 220 near its proximal end, and a sidewall 230 connecting the first bottom 210 and the second bottom 220. In some examples, a hollow portion may be formed between the first bottom 210, the second bottom 220, and the sidewall 230. In some examples, referring to FIG16A, a receiving portion 250 may be disposed in the second bottom 220 and facing the proximal end. In some examples, a piercing member 260 may be disposed within the hollow portion. In some examples, the second bottom 220 may have a through hole 226. Additionally, in some examples, the piercing member 260 may pass through the through hole 226.

[0394] In some examples, the puncture member 260 may be releasably disposed on the moving body 200, and the puncture member 260 may be configured to be movable relative to the receiving portion 250 when released. For example, when the puncture member 260 is released, it may move relative to the receiving portion 250 in a direction away from the host.

[0395] In some examples, the application device 1000 may also include a second drive mechanism 40 (see FIG. 16A). The second drive mechanism 40 may be configured to apply an action to the puncture member 260 in a distal manner. When the puncture member 260 is released, the puncture member 260 may be driven distally by the second drive mechanism 40 to disengage the puncture member 260 from the host.

[0396] In other examples, the application device 1000 may not include the second drive mechanism 40. In this case, the puncture member 260 can be manually driven away from the host. For example, in some examples, the puncture member 260 may also be integrally connected to the motion body 200, and the puncture member 260 may be moved away from the host by manually moving the motion body 200 in a direction away from the host.

[0397] In some examples, the puncture member 260 may be releasably disposed within the hollow portion of the moving body 200. In some examples, the puncture member 260 may move along the hollow portion of the moving body 200 when released. In this case, the hollow portion is formed by the first bottom 210, the second bottom 220, and the sidewall 230, and the receiving portion 250 is disposed in the second bottom 220, and the puncture member 260 is disposed in the hollow portion, thereby facilitating the movement of the puncture member 260 relative to the receiving portion 250 when released. Thus, when the medical device 800 is applied to the host, the puncture member 260 is released and moves relative to the receiving portion 250, thereby enabling the puncture member 260 to leave the host.

[0398] In other examples, the puncture component 260 may also be fixedly mounted on the moving body 200. In this case, when the medical device 800 is applied to the host, the moving body 200 can be manually removed from the host as a whole, thereby allowing the puncture component 260 to also leave the host.

[0399] Additionally, in some examples, the first limiting mechanism 150 may also include a protrusion 160 disposed on the inner wall (see Figure 15B, which will be described in detail later).

[0400] In some examples, a second drive mechanism 40 may be provided between the second bottom 220 of the moving body 200 and the puncture member 260. The second drive mechanism 40 is configured to apply an action to the puncture member 260 distally. When the puncture member 260 is released, the second drive mechanism 40 can apply an action to the puncture member 260 distally to disengage it from the host. In some examples, the second drive mechanism 40 may be located between the support 280 of the puncture member 260 and the second bottom 220 of the moving body 200. This facilitates the second drive mechanism 40 in applying an action to the puncture member 260 away from the receiving portion 250.

[0401] In some examples, as described above, the moving body 200 may include a sidewall 230. In some examples, the moving body 200 may include a limiting portion 238 disposed on the sidewall 230 (see FIG. 16B). The puncture member 260 may have a restrictive portion 285 (see FIG. 16B). When the puncture member 260 is assembled with the moving body 200, the moving body 200 may limit the restrictive portion 285 by means of the limiting portion 238 to limit the movement of the puncture member 260. In some examples, the number of limiting portions 238 may be one or more, such as one, two, three, or four. In some examples, multiple limiting portions 238 may be evenly distributed on the inner wall of the sidewall 230.

[0402] In some examples, the moving body 200 may further include a second retaining portion 242 (see Figures 16A and 16B). The piercing member 260 may have a second locking portion 286 (see Figures 16A and 16B). When the piercing member 260 is assembled with the moving body 200, the moving body 200 may interlock with the piercing member 260 via the second retaining portion 242 to retain the piercing member 260. In some examples, the retention of the piercing member 260 by the second retaining portion 242 may be a releasable retention. In some examples, the number of second retaining portions 242 may be one or more, such as one, two, three, or four. In one example, a plurality of second retaining portions 242 may be evenly distributed on the sidewall 230.

[0403] Additionally, in some examples, the motion body 200 can be configured to suppress rotation of the puncture member 260. In this case, by suppressing unwanted rotation of the puncture member 260 during application, the user experience during the application of the medical device 800 can be improved. In some examples, the motion body 200 can suppress unwanted rotation of the puncture member 260 during application via the application limiting portion 238.

[0404] Additionally, in some examples, the moving body 200 may include grooves and / or ridges disposed on the inner wall of the sidewall 230 generally along the central axis CA. In this case, by having the grooves and / or ridges disposed on the inner wall of the sidewall of the moving body 200 engage with the grooves and / or ridges of the puncture member 260, undesirable rotation of the puncture member 260 during application can be effectively suppressed. That is, in some examples, the limiting portion 238 of the moving body 200 may be grooves and / or ridges disposed on the inner wall of the sidewall 230 generally along the central axis CA.

[0405] In some examples, the limiting portion 238 of the moving body 200 may be formed as a groove structure. In some examples, the limiting portion 238 may include two ridges arranged side by side on the inner wall of the side wall 230 generally along the direction of the central axis CA, and a groove formed between the two ridges.

[0406] In some examples, the second retaining portion 242 of the moving body 200 can be a cut 242 formed on the sidewall 230 (see Figures 16A and 16B). That is, in some examples, the moving body 200 can have a cut 242 that is generally along the direction of the central axis CA (see Figures 16A and 16B). In this case, by providing a cut 242 along the direction of the central axis CA on the moving body 200, it is convenient to apply force to the piercing member 260 disposed in the hollow portion of the moving body 200.

[0407] In some examples, a protrusion 160 may be provided on the inner wall of the first limiting mechanism 150, which can protrude toward the central axis CA via a cut 242. In this case, when the moving body 200 moves along the first limiting mechanism 150, the protrusion 160 on the inner wall of the first limiting mechanism 150 can act on the piercing member 260 via the cut 242 of the moving body 200, thereby providing a triggering mechanism for the piercing member 260 with a simplified structure.

[0408] In some examples, the second retaining portion 242 may include a first cut 244, a second cut 246, and a third cut 248 that extend generally along the central axis CA and are interconnected. The first cut 244 may be proximal, and the third cut 248 may be distal. In some examples, the width of the second cut 246 may differ from the width of the first cut 244 and the width of the third cut 248. In some examples, the width of the second cut 246 may be greater than the widths of the first cut 244 and the third cut 248.

[0409] In some examples, the puncture member 260 may include a sharp object 270 and a support 280 supporting the sharp object 270 (see Figures 16A and 16B). In some examples, the support 280 of the puncture member 260 may be disposed within the hollow portion of the moving body 200, and the receiving portion 250 may be disposed at the second bottom 220, which may have a through hole 226 through which the sharp object 270 may pass. In this case, by providing the sharp object 270 through the through hole 226 of the second bottom 220, the sharp object 270 can engage with the medical device 800 housed within the receiving portion 250, thereby facilitating the placement of the medical device 800, at least partially, under the skin of the host via the puncture member 260.

[0410] Additionally, in some examples, the moving body 200 may also include a positioning structure 224 (see FIG. 14A) disposed on the second bottom 220 for positioning the second drive mechanism 40. In some examples, the positioning structure 224 may be cylindrical. In some examples, the positioning structure 224 may be hollow cylindrical. In this case, the second drive mechanism 40 can be positioned by fitting it onto the positioning structure 224, thereby defining the driving position of the second drive mechanism 40.

[0411] Additionally, in some examples, when the puncture member 260 is held, the distance between the support 280 and the first bottom 210 may be no less than the length of the sharp object 270 protruding from the receiving portion 250. In this case, by setting the distance between the support 280 and the first bottom 210 to be no less than the length of the sharp object 270 protruding from the receiving portion 250, space can be provided for the puncture member 260 to move away from the host, thereby reducing undesirable harm to the host caused by the puncture member 260.

[0412] In other examples, the sharp object 270 and the support 280 can be configured to be detachably assembled. This facilitates the separate sterilization of the sharp object 270.

[0413] In some examples, the confined portion 285 of the puncture member 260 may be formed as a ridge structure (see FIG. 16B). In some examples, the confined portion 285 may include two grooves arranged side-by-side on the sidewall of the support 280 generally along the central axis CA, and a ridge formed between the two grooves. In some examples, the number of confined portions 285 may be one or more, such as one, two, three, or four. In some examples, the number of confined portions 285 may be equal to the number of limiting portions 238.

[0414] Additionally, in some examples, the support 280 may include grooves and / or ridges disposed on the outer wall generally along the central axis CA. In this case, the grooves and / or ridges of the support 280 engage with grooves and / or ridges on the inner side wall of the moving body 200, thereby effectively suppressing undesirable rotation of the puncture member 260. That is, the limiting portion 285 of the puncture member 260 may be formed as grooves and / or ridges disposed on the outer wall generally along the central axis CA. The limiting portion 285 of the puncture member 260 may engage with the limiting portion 238 of the moving body 200 to suppress undesirable rotation of the puncture member 260.

[0415] Additionally, in some examples, the puncture member 260 may include a second locking portion 286 (see FIG. 17A) configured to releasably interlock with the second retaining portion 242. Thus, the puncture member 260 can be releasably retained in the second retaining portion 242 through the engagement of the second locking portion 286 with the second retaining portion 242. In some examples, the second locking portion 286 may be provided on the support 280 of the puncture member 260.

[0416] In some examples, the second locking portion 286 may include an arm 287 extending generally along the central axis CA, and a protrusion 288 linked to the arm 287 and projecting generally in a direction orthogonal to the central axis CA away from the central axis CA (see Figures 16A and 16B). In this case, when the piercing member 260 is placed within the hollow portion of the moving body 200, it overlaps with the cut 242 of the moving body 200 via the second locking portion 286 (see Figure 17A), thereby enabling the piercing member 260 to be held with a simplified structure. In some examples, the arm 287 of the second locking portion 286 may be elastic in a direction generally orthogonal to the central axis CA of the application device 1000.

[0417] As described above, the moving body 200 may have a cut 242 generally along the central axis CA. In some examples, when the piercing member 260 is held, the protrusion 288 of the second locking portion 286 may pass through the cut 242. In this case, by engaging the protrusion 288 of the second locking portion 286 with the cut 242 of the moving body 200, the second locking portion 286 can be held with a simplified structure.

[0418] Additionally, in some examples, when the puncture member 260 is released, the arm 287 of the second locking part 286 can be pressed toward the central axis CA. This allows for easy release of the second locking part 286.

[0419] Additionally, in some examples, the second retaining part 242 and the second locking part 286 can be releasably interlocked by at least one of the following structures: a latch, a hook, a bolt, or a pin. In this case, the second retaining part 242 and the second locking part 286 are releasably interlocked by at least one of the following structures, thereby providing an interlocking method that is easy to release.

[0420] In some examples, the second locking portion 286 of the puncture member 260 may be formed as a shoulder structure. In some examples, the second locking portion 286 may include an arm 287 extending distally in a direction generally along the central axis CA, and a protrusion 288 projecting from the end of the arm 287 in a direction generally orthogonal to and away from the central axis CA. In some examples, the arm 287 may be elastic. In some examples, the arm 287 may gradually move away from the central axis CA in a distal direction. In some examples, when projected along the central axis CA, the projection plane of the protrusion 288 may wholly or partially coincide with the projection plane of the first incision 244. In some examples, the number of second locking portions 286 may be one or more, such as one, two, three, or four. In some examples, the number of second locking portions 286 may be equal to the number of second retaining portions 242.

[0421] Additionally, in some examples, the width of the distal surface of the protrusion 288 may be less than the width of the second cut 246 and may be greater than the width of the first cut 224 and the second cut 246.

[0422] In some examples, when assembling the first limiting mechanism 150 and the moving body 200, the protrusion 160 provided on the inner wall of the first limiting mechanism 150 can pass sequentially through the third cut 248, the second cut 246, and the first cut 244. In this case, by providing the first cut 244, the protrusion 160 can protrude out of the moving body 200; by providing the second cut 246, a holding mechanism for the piercing member 260 can be provided; and by providing the third cut 248, a structure that facilitates assembly can be provided. The protrusion 160 enters the first cut 244 through the third cut 248 and the second cut 246, and the protrusion 288 of the second locking portion 286 protrudes through the second cut 246, thereby providing a retention mechanism for the piercing member 260. Additionally, the protrusion 160 can abut against the protrusion 288 of the second locking portion 286 through the first cut 244, thus providing a triggering mechanism for releasing the second locking portion 286. In some examples, the widths of the second cut 246 and the first cut 244 may be the same.

[0423] In some examples, the protrusion 160 can act on the second locking portion 286 in a direction orthogonal to the central axis CA. In this case, the second locking portion 286 is biased inward and separated from the host (see Figure 17B).

[0424] In some examples, after the puncture member 260 is released by the moving body 200, the second drive mechanism 40 drives the puncture member 260 toward the distal end to remove the puncture member 260 from the host.

[0425] In some examples, the second drive mechanism 40 may have the same or similar configuration as the first drive mechanism 30; for details regarding the characteristics of the second drive mechanism 40, please refer to the description of the characteristics of the first drive mechanism 30. In some examples, the second drive mechanism 40 may be a spring. Thus, an actuation mechanism for the puncture member 260 can be provided through a simplified structural design.

[0426] In some examples, the second drive mechanism 40 may be disposed between the support 280 and the second bottom 220, and when the puncture member 260 is held, the distance between the support 280 and the first bottom 210 is not less than the depth to which the sensor 820 is implanted subcutaneously. In this case, by providing sufficient space for movement for the puncture member 260, it is possible to facilitate the removal of the puncture member 260 from the host.

[0427] In some examples, the moving body 200 also includes a first marking portion 239 disposed on the side wall 230 (see FIG. 16B). In some examples, the first marking portion 239 may be used to limit the assembly direction of the support 280 to the moving body 200.

[0428] In some examples, the support 280 may include a second marking portion 281 that can be coupled to the first marking portion 239 (see FIG. 16B). In this case, the moving body 200 and the support 280 can have a unique assembly orientation.

[0429] In some examples, the first marking portion 239 may be a rib or groove formed on the sidewall 230 and extending along the central axis CA, and the second marking portion 281 may be a groove or rib formed on the support 280.

[0430] In some examples, when the puncture member 260 is triggered to unlock, the puncture member 260 can be driven to a position close to the distal end 120. In some examples, the puncture member 260 can be driven to a position abutting the distal end 120. Thus, the puncture member 260 can retract with its maximum stroke, reducing the risk of exposure of the puncture member 260.

[0431] In some examples, when the puncture member 260 is released, it can transition along a first path defined by the moving body 200 to a second path defined by the first housing 100.

[0432] In some examples, the process of the puncture member 260 being released and moving relative to the moving body 200 may include a first state in which the movement path is defined by the moving body 200, a second state in which the movement path is defined by the moving body 200 and the first housing 100, and a third state in which the movement path is defined by the first housing 100. This allows the puncture member 260 to leave the host along a predetermined path.

[0433] In some examples, referring to FIG12B, the first housing 100 may include a limiting portion 123 extending from the distal end 120. The limiting portion 123 may be used to receive the puncture member 260 and define the movement path of the puncture member 260.

[0434] In some examples, the support 280 may also include a notch 290 (see FIG. 16B). When the support 280 is assembled to the application device 1000, the notch 290 may be disposed on the same side as the first retaining portion 130. In this case, when the piercing member 260 transitions from the first path defined by the moving body 200 to the second path defined by the first housing 100, the first retaining portion 130 and / or the actuating portion 504 can pass through the notch, thereby allowing the piercing member 260 to enter the second path without obstruction.

[0435] In some examples, the puncture member 260 may have a positioning portion 289 disposed on the support 280 (see FIG. 16A). In some examples, the positioning portion 289 may be a columnar structure. One end of the second drive mechanism 40 may be sleeved on the positioning portion 289 of the puncture member 260, and the other end of the second drive mechanism 40 may be sleeved on the positioning portion 224 of the moving body 200 (see FIG. 14A). In this way, the second drive mechanism 40 is disposed between the moving body 200 and the puncture member 260.

[0436] In some examples, the application device 1000 also provides a triggering mechanism to disengage the second retaining portion 242 from the second locking portion 286, thereby releasing the piercing member 260 from the moving body 200. In this disclosure, this triggering mechanism may be referred to as a retraction triggering mechanism. That is, in some examples, the application device 1000 further includes a second triggering mechanism configured to separate the second retaining portion 242 from the second locking portion 286 to release the piercing member 260. Thus, the piercing member 260 can be conveniently released via the second triggering mechanism.

[0437] As described above, the second locking portion 286 is formed as a shoulder structure capable of abutting against the second retaining portion 242, thereby being held by the second retaining portion 242 in the form of a snap fastener. In some examples, a retraction trigger mechanism is provided, which can actuate the second retaining portion 242 or the second locking portion 286 to separate the second retaining portion 242 from the second locking portion 286.

[0438] In some examples, a retraction trigger mechanism acting on the second retaining portion 242 and the second locking portion 286 can be provided on the travel path of the second locking portion 286. This retraction trigger mechanism can be invoked when the moving body 200 moves towards the proximal end. In some examples, the retraction trigger mechanism can be a protrusion provided on the travel path of the second locking portion 286. In this case, when the second locking portion 286 passes the protrusion, the arm 287 of the second locking portion 286 can be compressed towards the central axis CA and undergo elastic deformation, causing the protrusion 288 of the second locking portion 286 to separate from the second cut 246 and the third cut 248.

[0439] In some examples, as previously described, a protrusion 160 is provided on the inner wall of the first limiting mechanism 150 (see Figure 15B). When the moving body 200 moves along the first limiting mechanism 150, the first cut 244, the second cut 246, and the third cut 248 of the moving body 200 can pass through this protrusion. Furthermore, when the piercing member 260 is held within the hollow portion of the moving body 200, the second locking portion 286 of the piercing member 260 is deformed by the pressure of the protrusion 160 and moves away from the junction of the second cut 246 and the third cut 248, thereby releasing the piercing member 260.

[0440] Furthermore, when assembling the moving body 200 and the first limiting mechanism 150, the protrusion 160 can sequentially pass through the third cut 248, the second cut 246, and the first cut 244 until the moving body 200 is assembled with the first limiting mechanism 150. By using the protrusion 160 on the inner wall of the first limiting mechanism 150, and the first cut 244, the second cut 246, and the third cut 248 on the side wall 230 of the moving body 200, a retraction triggering mechanism during movement can be provided without negatively impacting the assembly of the moving body 200 with the first limiting mechanism 150.

[0441] In some examples, after the application of the instrument kit 1 is completed, the motion body 200 can be applied in the proximal-to-distal direction to lock the motion body 200 back into the first holding part 130.

[0442] Figure 18A is a first-view cross-sectional view showing the medical device 800 applied to the device kit 1 according to the present disclosure example; Figure 18B is a second-view cross-sectional view showing the medical device 800 applied to the device kit 1 according to the present disclosure example. Figure 18C is a cross-sectional view showing a first perspective of the application of the medical device 800 by the device kit 1 according to the present disclosure example; Figure 18D is a cross-sectional view showing a second perspective of the application of the medical device 800 by the device kit 1 according to the present disclosure example; Figure 18E is a cross-sectional view showing the application of the medical device 800 by the device kit 1 according to the present disclosure example to the host; Figure 18F is a cross-sectional view showing the puncture member 260 in a second state after the application of the medical device 800 by the device kit 1 according to the present disclosure example; Figure 18G is a cross-sectional view showing the puncture member 260 in a third state after the application of the medical device 800 by the device kit 1 according to the present disclosure example; Figure 19A is a cross-sectional view showing the movement body 200 locked again in the first holding part 130 after the application of the medical device 800 by the device kit 1 according to the present disclosure example; wherein, Figures 18A-18G and Figure 19A do not show the first drive mechanism 30 and the second drive mechanism 40.

[0443] The application process of the application device 1000 will now be described again: applying the medical device 800 to the host via the application device 1000 may include an application phase and a withdrawal phase. In the application phase, the medical device 800 may be applied to the host; in the withdrawal phase, the puncture member 260 may be removed from the host.

[0444] In some examples, see Figures 18A and 18B, the moving body 200 is locked to the first retaining part 130 before the medical device 800 is applied.

[0445] During the application phase, pressing the pressing part 502 of the first triggering mechanism 50 causes the actuating part 504 of the first triggering mechanism 50 to actuate the first holding mechanism 130 to pivot in a direction away from the central axis CA, thereby separating the first holding part 130 from the first locking part 236 and releasing the moving body 200; then, the first driving mechanism 30 applies an action to the moving body 200 in a proximal manner to move the moving body 200 proximal; then, under the action of the puncture member 260, the medical device 800 contained in the receiving part 250 is at least partially placed under the skin of the host.

[0446] In some examples, the application device 1000 may not include the first drive mechanism 30. In this case, when the motion body 200 is released, the motion body 200 may also be driven toward the host by human power, thereby applying the medical device 800 contained in the receiving portion 250 to the host through the puncture member 260.

[0447] During the retraction phase, as the moving body 200 moves proximally along the first limiting mechanism 150, the protrusion 160 on the inner wall of the first limiting mechanism 150 passes through the second incision 246 on the moving body 200 and approaches the second locking portion 286 of the puncture member 260. The protrusion 160 presses the second locking portion 286 to cause the second locking portion 286 to pivot in a direction close to the central axis CA, thereby separating the second locking portion 286 from the second holding portion 242 (see Figures 18C and 18D). Then, the second drive mechanism 40 acts on the puncture member 260 in a distal manner to move the puncture member 260 distally and away from the host.

[0448] In some examples, referring to Figures 18A and 18B, the puncture member 260 may include a joint 2741 protruding from the bottom of the medical device 800. The joint 2741 protruding from the bottom of the medical device 800 means protruding from the bottom of the dressing portion 860. In some examples, the puncture member 260 may include a joint 2741 extending from the bottom of the body unit in a standby state. The standby state refers to the state before the application device 1000 has been assembled and houses the medical device 800 (i.e., the monitoring device), but before any application action has been performed. In this disclosure, the standby state may also be referred to as a shelf state or a standby phase.

[0449] In some examples, the medical device 800 has not yet been applied to the host when the second locking part 286 separates from the second retaining part 242 (referring to Figures 18C and 18D). At this time, the moving body 200 and the receiving part 250 can continue to be driven in the proximal direction, while the puncture member 260 can be driven in the distal direction. In this case, since the puncture member 260 is triggered to unlock in advance, when the medical device 800 is applied to the host, the puncture member 260 has already moved a distance distally relative to the moving body 200. As a result, the engaging part 2741 can assist in applying the medical device 800 to the host in a posture that does not protrude from the bottom of the medical device 800, thereby improving the user's comfort. For example, referring to Figures 18D and 18E, when the medical device 800 is applied to the host, the bottom of the engaging part 2741 is flush with the bottom of the medical device 800. In some examples, when the medical device 800 is applied to the host, the bottom of the junction 2741 may not protrude from the bottom of the medical device 800.

[0450] In some examples, the bottom of the joint 2741 may not protrude from the proximal end of the housing 10 throughout the application process. In some examples, when the timing of the triggering of the puncture mechanism 260 is appropriately set, the bottom of the joint 2741 may not protrude from the proximal end of the housing 10 throughout the application process. That is, the puncture mechanism 260 can be triggered to unlock either when the bottom of the joint 2741 moves to the proximal end of the housing 10 or before the bottom of the joint 2741 moves to the proximal end of the housing 10. In this case, the bottom of the joint 2741 does not act on the host, improving user comfort.

[0451] In some examples, referring to Figure 18E, when the medical device 800 is applied to the host, the protrusion 234 of the moving body 200 can abut against the notch 156. Specifically, the lower surface of the protrusion 234 of the moving body 200 can abut against the upper surface of the notch 156. This restricts further proximal movement of the moving body 200, thereby facilitating the subsequent movement of the puncture member 260 away from the host.

[0452] In some examples, the puncture member 260 may also be fixedly connected to the moving body 200. Additionally, in some examples, the application device 1000 may not include the second drive mechanism 40. In this case, after the medical device 800 is applied to the host, the moving body 200 can be driven manually in a direction away from the host, thereby allowing the puncture member 260, fixedly connected to the moving body 200, to follow the moving body 200 away from the host.

[0453] Furthermore, it should be noted that during the retraction phase, the first drive mechanism 30 (or with human intervention) can still exert an action on the moving body 200 towards the host. In other words, for the first drive mechanism 30, which is configured as an elastic component (e.g., a spring), when the moving body 200 is driven towards the host and the medical device 800 housed in the receiving portion 250 is applied to the host's body surface, the first drive mechanism 30 can still be in an energy-storing state. In this case, during the retraction phase, the medical device 800 is tightly attached to the host's body surface under the action of the first drive mechanism 30, thereby effectively reducing the possibility of the medical device 800 detaching from the host during the retraction phase.

[0454] In some examples, referring to Figures 18F and 18G, the piercing member 260 can be driven to a position abutting against the first housing 100. In some examples, the limiting portion 123 can receive the protrusion 288 of the second locking portion 286. In some examples, the size of the protrusion 288 of the second locking portion 286 can be equal to or slightly smaller than the size of the limiting portion 123. Figure 18F shows a second state in which the piercing member 260 is in a movement path restricted by the moving body 200 and the limiting portion 123 of the first housing 100, and Figure 18G shows a third state in which the piercing member 260 is in a movement path restricted by the limiting portion 123 of the first housing 100.

[0455] In some examples, referring to Figure 19A, the moving body 200 can be locked again to the first retaining part 130. In some examples, the moving body 200 can be acted on in a direction toward the distal end so that the moving body 200 can be locked again to the first retaining part 130. In some examples, when the moving body 200 can be locked again to the first retaining part 130, the cap 700 can be coupled to the housing 10. This facilitates the storage and organization of the instrument set 1.

[0456] In some examples, the application device 1000 may include a triggering mechanism that allows relative movement of the engagement 2741 with respect to the body unit 860 so that the engagement 2741 does not protrude from the bottom of the body unit 860. This triggering mechanism is referred to as a first triggering mechanism. In some examples, the first triggering mechanism may be located on the travel path of the auxiliary mechanism 20. In some examples, the first triggering mechanism may be configured to allow relative movement of the engagement 2741 with respect to the body unit 860 during proximal movement of the auxiliary mechanism 20 so that the engagement 2741 does not protrude from the bottom of the body unit 860. In this case, by utilizing the first triggering mechanism set on the travel path of the auxiliary mechanism 20, the joint 2741 protruding from the bottom of the body unit 860 can move relative to the body unit 860 as the auxiliary mechanism 20 approaches the proximal end, so that the joint 2741 does not protrude from the bottom of the body unit 860. That is, this disclosure integrates the action of retracting the joint 2741 into the process of the first drive mechanism 30 pushing the auxiliary mechanism 20 to automate the process. Such a design can eliminate the need for the user to perform an additional operation of retracting the joint 2741 before the monitoring device 800 is applied to the host using the application device 1000. This makes it easy for the user to use, and eliminates the need for a complex linkage structure, thereby reducing the risk of mechanical failure and improving the reliability and safety of the application device 1000.

[0457] In some examples, the first triggering mechanism can be triggered either when the bottom of the joint 2741 moves to the proximal end of the housing 10 or before the bottom of the joint 2741 moves to the proximal end of the housing 10. Here, the bottom of the joint 2741 refers to its end closest to the proximal end, and in examples where the housing 10 includes a first outer shell 100 and a second outer shell 140, the proximal end of the housing 10 refers to the proximal end of the first outer shell 100. This allows the joint 2741 to be easily retracted to a position that does not protrude from the bottom of the body unit 860 before it comes into contact with the host's skin.

[0458] In some examples, the first triggering mechanism can cause the moving body 200 to release the puncture member 260. In some examples, the first triggering mechanism can cause the moving body 200 to release the puncture member 260 as the moving body 200 and the puncture member 260 approach the proximal end together (i.e., after the moving body 200 is released, the auxiliary mechanism 20 as a whole approaches the proximal end). In this case, releasing the puncture member 260 by the moving body 200 through the first triggering mechanism facilitates relative movement between the engagement portion 2741 and the body unit 860 so that the engagement portion 2741 does not protrude from the bottom of the body unit 860. In some examples, the first triggering mechanism can be located on the travel path of the puncture member 260.

[0459] In some examples, as previously described, the application device 1000 may further include a second drive mechanism 40, which can apply force to the puncture member 260 in a distal manner. When the puncture member 260 is released by the moving body 200, the puncture member 260 moves distally under the action of the second drive mechanism 40. In this case, the second drive mechanism 40 enables, on the one hand, to move the engagement portion 2741 distally to a position that does not protrude from the bottom of the body unit 860 after the puncture member 260 is released, and on the other hand, it also facilitates automatic needle return after the puncture member 260 assists in implanting the sensor 820 subcutaneously into the host.

[0460] In some examples, as previously described, the application device 1000 also provides a retraction trigger mechanism to release the second holding portion 242 from the interlock with the second locking portion 286. In some examples, the first trigger mechanism can be the aforementioned retraction trigger mechanism. That is, the retraction trigger mechanism can cause the moving body 200 to release the puncture member 260, which, under the action of the second drive mechanism 40, can move distally, displacing the engagement portion 2741 to a position that does not protrude from the bottom of the body unit 860, and the puncture member 260 can continue to move distally to leave the host. In some examples, this effect can be achieved by appropriately setting the timing of the puncture mechanism 260 being triggered to unlock. Specifically, the retraction trigger mechanism can be invoked when the bottom of the engagement portion 2741 moves to the proximal end of the housing 10 or before the bottom of the engagement portion 2741 moves to the proximal end of the housing 10, and after the sharp object 270 has guided the sensor 820 to be implanted subcutaneously into the host at a predetermined depth. In this scenario, when the retraction trigger mechanism is invoked, the sharp object 270 guides the sensor 820 to implant at a predetermined depth under the host's skin, while simultaneously initiating the retraction of the junction 2741, which helps reduce the probability of the junction 2741 coming into contact with the host's skin.

[0461] In some examples, before the suprabody unit 860 is applied to the host, the puncture member 260 is released in advance so that the puncture member 260 assists in placing the sensor 820 at least partially under the host's skin in a posture where the engagement 2741 does not protrude from the bottom of the suprabody unit 860. In this case, it is convenient to retract the engagement 2741 to a position where it does not protrude from the bottom of the suprabody unit 860 before the engagement 2741 comes into contact with the host's skin, without affecting the sharp object 270's assistance in inserting the sensor 820 into the host's subcutaneous tissue.

[0462] In some examples, the moving body 200 can hold the puncture member 260 in segments. In some examples, the application device 1000 also includes a second triggering mechanism. A first triggering mechanism can cause the moving body 200 to initially release the puncture member 260, and a second triggering mechanism can cause the moving body 200 to release the puncture member 260 a second time. In some examples, the puncture member 260, after being released a second time, leaves the host under the action of the second drive mechanism 40. That is, the first triggering mechanism causes the moving body 200 to initially release the puncture member 260 so that the joint 2741 does not protrude from the bottom of the body unit 860, and the second triggering mechanism causes the moving body 200 to release the puncture member 260 a second time, and the puncture member 260, after being released a second time, leaves the host under the action of the second drive mechanism 40. In this case, it is convenient to achieve segmented retraction of the puncture member 260 during the pushing of the monitoring device 800. Compared with setting a separate trigger mechanism at an appropriate position to achieve the two purposes of retraction of the joint 2741 and departure from the host in a single retraction process, this design of segmented retraction by using the first trigger mechanism in conjunction with the second trigger mechanism can help ensure that the joint 2741 is retracted to a position that does not protrude from the bottom of the body unit 860 before moving to the proximal end of the housing 10, and does not affect the auxiliary implantation function of the puncture member 260 in assisting the implantation of the sensor 820 under the host skin, thereby improving the reliability of the application device 1000.

[0463] In some examples, the second triggering mechanism can be set on the travel path of the puncture member 260. That is, the application device 1000 may also include a second triggering mechanism set on the travel path of the puncture member 260. As mentioned above, the application device 1000 also provides a retraction triggering mechanism to release the second holding part 242 from the interlock with the second locking part 286. In some examples, the second triggering mechanism may be the aforementioned retraction triggering mechanism. That is, the retraction triggering mechanism can cause the moving body 200 to release the puncture member 260, and the released puncture member 260 can move distally to leave the host under the action of the second drive mechanism 40. In this case, in the scheme where the puncture member 260 can automatically retract from the host subcutaneous tissue, a one-time retraction can be achieved using the retraction triggering mechanism. Based on this, only an additional first triggering mechanism needs to be added to automatically and reliably achieve the two-stage retraction of the puncture member 260 during the pushing process of the application device 1000. That is, the reliability of the application device 1000 can be significantly improved with minimal design modifications.

[0464] In some examples, as previously described, the moving body 200 may include a second retaining portion 242, and the piercing member 260 may include a second locking portion 286 releasably interlocked with the second retaining portion 242. Thus, the piercing member 260 can be releasably disposed on the moving body 200 through the cooperation of the second retaining portion 242 and the second locking portion 286.

[0465] Figure 19B is a schematic diagram illustrating the second retaining portion 242 of another embodiment according to the present disclosure. In Figure 19B, for clarity, the first retaining surface 2421 and the second retaining surface 2422 are not shown directly; only the side outlines of the two retaining surfaces are shown.

[0466] In some examples, the second retaining portion 242 may have a first retaining surface 2421 and a second retaining surface 2422 facing the proximal end (see FIG. 19B). In the standby state, the second locking portion 286 is in contact with and restricted by the first retaining surface 2421; after the first triggering mechanism is activated, the second locking portion 286 separates from the first retaining surface 2421 and, under the action of the second drive mechanism 40, the piercing member 260 moves to contact with and is restricted by the second retaining surface 2422; after the second triggering mechanism is activated, the second locking portion 286 separates from the second retaining surface 2422 and, under the action of the second drive mechanism 40, the piercing member 260 continues to move toward the distal end to leave the host. Thus, a retaining member with a simple structure can be provided, which helps to optimize the internal structural arrangement of the application device 1000 and to enable the overall miniaturization of the application device 1000.

[0467] As previously described, in some examples, the moving body 200 may have a cut 242 generally along the central axis CA, and the protrusion 288 of the second locking portion 286 may overlap the cut 242. In some examples, the first retaining surface 2421 may be arranged adjacent to the cut 242. Specifically, when the protrusion 288 overlaps the cut 242, the surface of the cut 242 that contacts the top surface of the protrusion 288 may be the first retaining surface 2421. "The first retaining surface 2421 is arranged adjacent to the cut 242" means that the space formed by the first retaining surface 2421 and the cut 242 is arranged adjacent to each other. In some examples, where the protrusion 288 overlaps the second cut 246, the surface of the second cut 246 that contacts the top surface of the protrusion 288 may be the first retaining surface 2421.

[0468] In some examples, the second retaining surface 2422 may be arranged adjacent to the cut 242. In some examples, the second retaining surface 2422 may be arranged adjacent to the first retaining surface 2421. In some examples, the second retaining surface 2422 and the first retaining surface 2421 may be arranged adjacent to each other along a direction from distal to proximal. This allows the piercing member 260 to move smoothly to a position restricted by the second retaining surface 2422 after being released from the retention of the first retaining surface 2421.

[0469] In some examples, the distance between the second retaining surface 2422 and the first retaining surface 2421 along the central axis CA may be no less than the distance by which the joint 2741 protrudes from the bottom of the body unit 860. In this case, the travel distance by which the piercing member 260 moves to the position limited by the second retaining surface 2422 after disengaging from the first retaining surface 2421 is sufficient to allow the joint 2741 to retract to a position that does not protrude from the bottom of the body unit 860. In some examples, the distance between the second retaining surface 2422 and the first retaining surface 2421 along the central axis CA may be greater than the distance by which the joint 2741 protrudes from the bottom of the body unit 860.

[0470] Figure 19C is a schematic diagram illustrating the first protruding structure 161 and the second protruding structure 162 involved in the examples of this disclosure.

[0471] In some examples, the first triggering mechanism may include a protruding structure disposed on the travel path of the piercing member 260 (see FIG. 19C). This protruding structure of the first triggering mechanism is referred to as the first protruding structure 161. When the first triggering mechanism is invoked, the first protruding structure 161 can act on the second locking portion 286 or the second retaining portion 242 to deform it and separate the second locking portion 286 from the second retaining portion 242. This provides a triggering member with a simple structure, contributing to the optimization of the internal structural arrangement and overall miniaturization of the application device 1000.

[0472] In some examples, the second triggering mechanism may include a protruding structure disposed on the travel path of the piercing member 260 (see FIG. 19C). This protruding structure of the second triggering mechanism is referred to as the second protruding structure 162. When the second triggering mechanism is invoked, the second protruding structure 162 can act on the second locking portion 286 or the second retaining portion 242 to deform it and separate the second locking portion 286 from the second retaining portion 242. Thus, a triggering member with a simple structure can be provided, which helps to optimize the internal structural arrangement of the application device 1000 and to achieve overall miniaturization of the application device 1000.

[0473] In some examples, the first protruding structure 161 may be formed on the inner wall of the housing 10 and protrude toward the central axis CA of the application device 1000. In some examples, the second protruding structure 162 may be formed on the inner wall of the housing 10 and protrude toward the central axis CA of the application device 1000. As previously described, the retraction triggering mechanism may be a protrusion provided on the travel path of the second locking portion 286. For example, the retraction triggering mechanism may be a protrusion 160 on the inner wall of the first limiting mechanism 150. When the second triggering mechanism is a retraction triggering mechanism, the second protruding structure 162 of the second triggering mechanism may be a protrusion 160 on the inner wall of the first limiting mechanism 150.

[0474] In some examples, the first protruding structure 161 and the second protruding structure 162 can both be formed on the inner wall of the housing 10 and protrude in the direction of the central axis CA of the application device 1000. This provides two simple triggering structures, which helps optimize the internal structural arrangement and overall miniaturization of the application device 1000. Furthermore, in a scheme where the puncture member 260 can automatically retract from the host's subcutaneous tissue, a single protruding structure (e.g., protrusion 160) can achieve one-time retraction. Based on this, only one additional protruding structure (i.e., the first protruding structure 161) needs to be added to automatically and reliably achieve two-stage retraction of the puncture member 260 during the pushing process of the application device 1000. That is, the reliability of the application device 1000 can be significantly improved with minimal design modifications. In some examples, the first protruding structure 161 and the second protruding structure 162 can both be formed on the inner wall of the second housing 140 and protrude in the direction of the central axis CA of the application device 1000. In some examples, the first protruding structure 161 and the second protruding structure 162 may both be formed on the inner wall of the first defining mechanism 150 and protrude toward the central axis CA of the application device 1000.

[0475] In some examples, the first protruding structure 161 and the second protruding structure 162 may protrude toward the central axis CA via a cut 242. In some examples, the first protruding structure 161 and the second protruding structure 162 may protrude toward the central axis CA via a second cut 246.

[0476] In some examples, when the first triggering mechanism is invoked, the arm of the second locking portion 286 is pressed by the first protruding structure 161 toward the central axis CA, causing the protrusion of the second locking portion 286 to move away from the first holding surface 2421 to initially release the puncture member 260; when the second triggering mechanism is invoked, the arm of the second locking portion 286 is pressed by the second protruding structure 162 toward the central axis CA, causing the protrusion of the second locking portion 286 to move away from the second holding surface 2422 to release the puncture member 260 a second time. This facilitates a two-stage release of the puncture member 260.

[0477] In some examples, the adjacent first retaining surface 2421 and the second retaining surface 2422 can be stepped. That is, the first retaining surface 2421 and the second retaining surface 2422 can be two adjacent stepped surfaces. The second retaining surface 2422 can be closer to the central axis CA than the first retaining surface 2421. This facilitates providing a simplified second retaining portion 242. In some examples, the deformation of the locking or retaining portion when the first protruding structure 161 acts on the locking or retaining portion is smaller than that of the second protruding structure 162. In this case, by designing two triggers with different deformations, it is convenient to arrange the two retaining surfaces of the retaining portion continuously (e.g., forming two consecutive stepped surfaces), simplifying the structure of the retaining portion. In some examples, the end of the second protruding structure 162 is closer to the central axis CA of the applying device 1000 than the end of the first protruding structure 161. Therefore, the two protruding structures can easily cooperate with the two retaining surfaces forming two adjacent stepped surfaces to form a simplified segmented retaining structure of the moving body 200 on the piercing member 260.

[0478] In some examples, the first protruding structure 161 and the second protruding structure 162 are sequentially formed on the inner wall of the housing 10 along a direction from distal to proximal. This facilitates the two-stage retraction of the piercing member 260 as it moves from distal to proximal. Referring to Figure 19C, the first protruding structure 161 and the second protruding structure 162 are sequentially formed on the inner wall of the second housing 140 along a direction from distal to proximal. In some examples, the first protruding structure 161 and the second protruding structure 162 may be integrally formed with the second housing 140.

[0479] In some examples, a portion of the distal surface of the first protruding structure 161 may be inclined (see FIG. 19C). This facilitates the application of an action to the protrusion 288 to guide the protrusion 288 and arm 287 to retract inward. In some examples, a portion of the distal surface of the second protruding structure 162 may be inclined (see FIG. 19C). This facilitates the application of an action to the protrusion 288 to guide the protrusion 288 and arm 287 to retract inward.

[0480] In some examples, the first retaining surface 2421 may be offset from the first protruding structure 161 in the direction along the central axis CA. That is, when projected along the central axis CA, the first retaining surface 2421 and the first protruding structure 161 may not overlap. For example, the first retaining surface 2421 may be formed on the left and right sides of the second incision 246, and the first protruding structure 161 may be located in the incision 242. In the standby state, the protrusion 288 may abut against the first retaining surfaces 2421 located on the left and right sides of the second incision 246. In this case, as the puncture member 260 moves towards the proximal end, the first protruding structure 161 may act along the incision 242 towards the middle position of the protrusion 288 spanning the second incision 246. At this time, the first protruding structure 161 will not be blocked by the first retaining surface 2421, thus not hindering the movement of the moving body 200 towards the proximal end.

[0481] In some examples, the second retaining surface 2422 may be offset from the second protruding structure 162 in the direction along the central axis CA. The specific structure is the same as that of the first retaining surface 2421 and the first protruding structure 161. That is, when projected along the central axis CA, the second retaining surface 2422 and the second protruding structure 162 may not overlap. In some examples, when projected along the central axis CA, the first retaining surface 2421 and the second protruding structure 162 may not overlap. In some examples, when projected along the central axis CA, the second retaining surface 2422 and the first protruding structure 161 may not overlap.

[0482] Figure 19D is a schematic diagram illustrating the initial retraction of the joint 2741 according to the example of this disclosure. Figure 19E is a schematic diagram illustrating the secondary retraction of the puncture member 260 according to the example of this disclosure. In Figures 19D and 19E, for clarity, cross-sectional lines, the two drive mechanisms, and other components that may cause obstruction or misunderstanding are omitted, and the moving body 200 only shows the structure of the two holding surfaces of the second holding part 242. Line S1 schematically represents the proximal surface of the second outer shell 140, and line S2 schematically represents the proximal surface of the first outer shell 100 (which can also be understood as a schematic location of the host's skin surface).

[0483] Now, the segmented retraction process of the puncture member 260 is described again: During the entire pushing process of the application device 1000 applying the monitoring device 800 to the host, the puncture member 260 is segmentally held by the moving body 200. After the puncture member 260 is initially released by the moving body 200, the puncture member 260 moves distally relative to the moving body 200 under the action of the second drive mechanism 40 to a position where the joint 2741 does not protrude from the bottom of the body unit 860. At this time, the puncture member 260 falls into the second segment holding structure of the moving body 200. Then, the entire auxiliary mechanism 20 continues to move proximally under the action of the first drive. When the second trigger mechanism is invoked, the puncture member 260 is released a second time by the moving body 200. The puncture member 260, which is released a second time, moves distally relative to the moving body 200 under the action of the second drive mechanism 40 to leave the host.

[0484] Referring to Figures 19D-19E, part (a) of Figure 19D is a schematic diagram showing the puncture member 260 held at the position of the first holding surface 2421 in the standby state. As the moving body 200 and the puncture member 260 move together toward the proximal end, when the protrusion 288 of the second locking part 286 in the puncture member 260 contacts the first protruding structure 161, the protrusion 288 and the arm 287 are squeezed inward by the first protruding structure 161 and released from the holding of the first holding surface 2421, so that the puncture member 260 is initially released by the moving body 200 (see part (b) of Figure 19D). After the initial release, the puncture member 260 moves toward the distal end relative to the moving body 200 under the action of the second drive mechanism 40 to a position where the joint 2741 does not protrude from the bottom of the body unit 860. At this time, the puncture member 260 falls into the moving body. In the second holding structure (second holding surface 2422) of the moving body 200 (see part (c) of FIG19D); then, the moving body 200 and the puncture member 260 held by its second section move towards the proximal end under the action of the first drive mechanism 30 (see part (d) of FIG19E); when the movement reaches the point where the protrusion 288 of the second locking part 286 in the puncture member 260 contacts the second protruding structure 162, the protrusion 288 and the arm 287 are squeezed inward by the second protruding structure 162 to disengage from the holding of the second holding surface 2422 so that the puncture member 260 is released by the moving body 200 for a second time (see part (e) of FIG19E); after the initial release, the puncture member 260 moves towards the distal end relative to the moving body 200 under the action of the second drive mechanism 40 to leave the host (see part (f) of FIG19E).

[0485] Throughout the entire process of the application device 1000 applying the monitoring device 800 to the host, the first drive mechanism 30 always applies a proximal pushing force to the moving body 200. The initial retraction of the puncture member 260 in the middle does not affect the overall positional relationship of the auxiliary mechanism 20 moving towards the proximal end, and the movement of the monitoring device 800 housed in the moving body 200 towards the proximal end is not affected.

[0486] In some examples, preferably, the monitoring device 800 may include an on-body unit 860 and a sensor 820, and the application device 1000 may include a housing 10, an auxiliary mechanism 20 releasably held in the housing 10, and a drive mechanism. The auxiliary mechanism 20 includes a moving body 200 that accommodates the monitoring device 800 and a puncture member 260. The housing 10 has a proximal end that is close to the host during operation and a distal end that is far from the host. The puncture member 260 includes an engagement portion 2741 that extends out of the bottom of the on-body unit 860 in the standby state and punctures... The component 260 is configured to place the sensor 820 at least partially under the skin of the host. The drive mechanism applies an action to the auxiliary mechanism 20 in a proximal manner. The application device 1000 includes a first trigger mechanism disposed on the travel path of the auxiliary mechanism 20. After being released by the housing 10, the auxiliary mechanism 20 moves proximal under the action of the drive mechanism. As the auxiliary mechanism 20 approaches the proximal end, the first trigger mechanism causes the engagement 2741 to move relative to the body unit 860 so that the engagement 2741 does not protrude from the bottom of the body unit 860. In this configuration, by utilizing a first triggering mechanism positioned along the travel path of the auxiliary mechanism 20, the joint 2741 protruding from the bottom of the body unit 860 can move relative to the body unit 860 as the auxiliary mechanism 20 approaches its proximal end, achieving a position where the joint 2741 no longer protrudes from the bottom of the body unit 860. In other words, this disclosure integrates the action of retracting the joint 2741 into the process of the drive mechanism pushing the auxiliary mechanism 20, automating the process. This design eliminates the need for additional retraction of the joint 2741 by the user before applying the monitoring device 800 to the host using the application device 1000. This facilitates user operation, eliminates the need for complex linkage structures, reduces the risk of mechanical failure, and improves the reliability and safety of the application device 1000. Therefore, according to this disclosure, a user-friendly and highly reliable application device 1000 can be provided.

[0487] In some examples, as previously described, the application device 1000 may further include a cap having an inner cavity, the cap being configured to couple with the engagement 2741 to form a sealed space accommodating at least a portion of the sensor 820, wherein when the cap is coupled to the engagement 2741, the tail of the sensor 820 is located within the sealed space. This facilitates the isolation of the sensor 820 from external contamination in a standby state.

[0488] In other examples, the second retaining portion 242 may include a fourth cut that extends along the central axis CA and communicates with the second cut 246 and the third cut 248, and the fourth cut may be formed in the middle of the third cut 248. In this case, the fourth cut is closer to the distal end than the second cut 246. The first holding surface 2421 can be the surface of the second incision 246 that contacts the top surface of the protrusion 288. After the initial release of the piercing member 260, the arm 287 of the second locking part 286 is first squeezed and deformed in the direction of the central axis CA, causing the protrusion 288 to leave the first holding surface 2421. The released piercing member 260 moves toward the distal end to the position of the fourth incision under the action of the second driving mechanism 40. The arm 287 rebounds outward, causing the protrusion 288 to enter the fourth incision. At this time, the top surface of the protrusion 288 abuts against the downward-facing surface of the fourth incision (i.e., the second holding surface 2422), thus restricting the piercing member 260 to the second holding surface 2422. When the auxiliary mechanism 20 moves to the position where the second triggering mechanism is invoked, the second triggering mechanism can apply an action toward the protrusion 288 in the direction of the central axis CA, causing the arm 287 to deflect and thus causing the protrusion 288 to leave the second holding surface 2422. Subsequently, under the action of the second driving mechanism 40, it moves toward the distal end and leaves the host.

[0489] In other examples, as the auxiliary mechanism 20 approaches the proximal end, the first triggering mechanism can actuate the monitoring device 800 to move relative to the joint 2741 and move a distance toward the proximal end relative to the joint 2741 so that the joint 2741 does not protrude from the bottom of the body unit 860.

[0490] In other examples, as the auxiliary mechanism 20 approaches the proximal end, the first triggering mechanism actuates the needle shank to move relative to the monitoring device 800 and move a distance toward the distal end relative to the monitoring device 800 so that the engagement 2741 does not protrude from the bottom of the body unit 860.

[0491] Embodiments of this disclosure include:

[0492] C. An instrument kit comprising a puncture member and an application device cooperating with the puncture member to apply the medical device to a host, the application device comprising a housing and an auxiliary mechanism, the housing comprising a proximal end proximal to the host during operation and a distal end distal to the host, the auxiliary mechanism releasably holding the medical device and movable relative to the housing upon release, the auxiliary mechanism being configured to be driven in a proximal direction upon release to place the medical device at least partially under the skin of the host via the puncture member, and to drive the puncture member away from the host in response to an action on the application device in a distal direction.

[0493] In some examples, Embodiment C may be combined with any one or more of the following additional elements: Element 1: The auxiliary mechanism includes a motion body releasably held in the housing and configured to be movable relative to the housing when released, and a receiving portion disposed in the motion body and configured to receive and accommodate the medical device. Element 2: The puncture mechanism is releasably held in the motion body and configured to be movable relative to the receiving portion when released. Element 3: It further includes a second drive mechanism configured to apply force to the puncture member toward the distal end. Element 4: When the puncture mechanism is released, the puncture member is driven away from the host in response to the action applied to the puncture member by the second drive mechanism. Element 5: The puncture member includes a grooved sharp object and a support for supporting the sharp object, the medical device being wholly or partially placed in the groove of the sharp object, and the second drive mechanism being configured to apply force to the support.

[0494] Element 6: The moving body includes a second retaining portion for holding the puncture member, the puncture member including a second locking portion configured to releasably interlock with the second retaining portion. Element 7: The moving body has a first bottom near the distal end, a second bottom near the proximal end, a sidewall connecting the first bottom and the second bottom, and a hollow portion formed between the first bottom, the second bottom, and the sidewall, the receiving portion being disposed at the second bottom and movable along the hollow portion when the puncture member is released. Element 8: The second locking portion includes an arm extending generally along the central axis of the application device, and a protrusion disposed on the arm and projecting generally away from the central axis of the application device in a direction orthogonal to the central axis of the application device. Element 8: The moving body has a cutout generally along the central axis of the application device, and when the puncture member is held, the protrusion of the second locking portion passes through the cutout.

[0495] Element 9: The puncture member includes a second locking portion configured to releasably interlock with the second retaining portion and disposed on the support. The second locking portion includes an arm extending generally along the central axis of the application device, and a protrusion linked to the arm and projecting generally away from the central axis of the application device in a direction orthogonal to the central axis of the application device. Element 10: A protrusion is provided on the inner wall of the first defining mechanism, which can project toward the central axis of the application device via the incision. Element 2: The arm of the second locking portion is elastic in a direction generally orthogonal to the central axis of the application device.

[0496] Element 11: The moving body has a cut approximately along the central axis of the application device, and when the piercing member is held, the protrusion of the second locking portion passes through the cut. Element 12: When the piercing member is released, the arm of the second locking portion is pressed toward the central axis of the application device.

[0497] Element 13: When the puncture member is released, it can transition along a first path defined by the moving body to a second path defined by the first housing. Element 14: The first housing includes a limiting portion disposed at the distal end for defining the second path. Element 15: Projected along the central axis of the application device, the limiting portion defining the second path at least partially coincides with the moving body. Element 16: The process of the puncture member being released and moving relative to the moving body includes a first state in which a movement path is defined by the moving body, a second state in which a movement path is defined by the moving body and the housing, and a third state in which a movement path is defined by the housing. Element 17: The support has a notch in a direction generally along the central axis of the application device, through which the first retaining portion passes when the puncture member transitions to the second path. Element 18: The moving body can be actuated in a direction toward the distal end to lock the first locking portion into the first retaining portion. Element 19: The support is configured to be fitted onto the moving body in a predetermined direction.

[0498] Element 20: The application device includes a first triggering mechanism, which can be configured to move the joint relative to the body unit during the movement of the auxiliary mechanism toward the proximal end so that the joint does not protrude from the bottom of the body unit. Element 21: The first triggering mechanism can be disposed on the travel path of the auxiliary mechanism. Element 22: The first triggering mechanism can be triggered when the bottom of the joint moves to the proximal end of the housing or before the bottom of the joint moves to the proximal end of the housing.

[0499] Element 23: The first triggering mechanism allows the moving body to release the puncture member so that the joint and the body unit move relative to each other so that the joint does not protrude from the bottom of the body unit. Element 24: The application device also provides a retraction triggering mechanism to release the second holding part from the interlocking of the second locking part. Element 25: The first triggering mechanism can be the aforementioned retraction triggering mechanism, which allows the moving body to release the puncture member. The released puncture member can move distally under the action of the second drive mechanism, displacing the joint to a position where it does not protrude from the bottom of the body unit, and the puncture member can continue to move distally to leave the host. Element 26: Before the body unit is applied to the host, the puncture member is released in advance so that the puncture member assists in placing the sensor at least partially under the host's skin in an attitude where the joint does not protrude from the bottom of the body unit.

[0500] Element 27: The moving body can hold the puncture member in segments. The application device also includes a second triggering mechanism. The first triggering mechanism can cause the moving body to release the puncture member initially, and the second triggering mechanism can cause the puncture member to be released a second time by the moving body. Element 28: The first triggering mechanism causes the puncture member to be released by the moving body initially so that the joint does not protrude from the bottom of the body unit, and the second triggering mechanism causes the puncture member to be released a second time by the moving body. The puncture member released a second time leaves the host under the action of the second drive mechanism. Element 29: The second triggering mechanism can be set on the travel path of the puncture member. Element 30: The second triggering mechanism can be the aforementioned retraction triggering mechanism. That is, the retraction triggering mechanism can cause the moving body to release the puncture member, and the released puncture member can move toward the distal end to leave the host under the action of the second drive mechanism. Element 31: The second holding part can have a first holding surface and a second holding surface facing the proximal end. Element 32: In the standby state, the second locking part is in contact with and restricted by the first retaining surface; after the first triggering mechanism is invoked, the second locking part separates from the first retaining surface and the piercing member moves to contact with and is restricted by the second retaining surface under the action of the second driving mechanism; after the second triggering mechanism is invoked, the second locking part separates from the second retaining surface and the piercing member continues to move toward the distal end to leave the host under the action of the second driving mechanism.

[0501] Element 33: The first retaining surface and / or the second retaining surface may be arranged adjacent to the cut. Element 34: The second retaining surface and the first retaining surface may be arranged adjacent to each other along a direction from the distal end to the proximal end. Element 35: The adjacent first retaining surface and the second retaining surface may be stepped. Element 36: The second retaining surface may be closer to the central axis than the first retaining surface.

[0502] Element 37: The first triggering mechanism may include a first protruding structure disposed on the travel path of the puncture member. When the first triggering mechanism is activated, the first protruding structure can act on the second locking portion or the second retaining portion to deform and separate the second locking portion and the second retaining portion. Element 38: The second triggering mechanism may include a second protruding structure disposed on the travel path of the puncture member. When the second triggering mechanism is activated, the second protruding structure can act on the second locking portion or the second retaining portion to deform and separate the second locking portion and the second retaining portion. Element 39: Both the first and second protruding structures may be formed on the inner wall of the housing and protrude towards the central axis of the application device. Element 40: The first and second protruding structures may protrude towards the central axis via a cut. Element 41: Compared to the second protruding structure, the deformation of the locking portion or retaining portion when the first protruding structure acts on it is smaller. Element 42: The first and second protruding structures are sequentially formed on the inner wall of the housing along a direction from distal to proximal. Element 43: The first and second protruding structures can be integrally formed with the second housing. Element 44: The second retaining portion can include a fourth cutout, which can extend along the central axis and communicate with the second and third cutouts, and the fourth cutout can be formed in the middle of the third cutout.

[0503] Element 45: As the auxiliary mechanism approaches the proximal end, the first triggering mechanism can actuate the monitoring device to cause relative movement with respect to the joint and to move a distance relative to the joint toward the proximal end so that the joint does not protrude from the bottom of the body unit.

[0504] Element 46: As the auxiliary mechanism approaches the proximal end, the first triggering mechanism actuates the needle shank to move relative to the monitoring device and move a distance toward the distal end relative to the monitoring device so that the joint does not protrude from the bottom of the body unit.

[0505] In some examples, embodiment C, and embodiments combining embodiment C with any one or more of the corresponding elements 1 to 46, can be combined with embodiment A, the combination of embodiment A and its corresponding elements, embodiment B, and the combination of embodiment B and its corresponding elements.

[0506] Figure 20A is an exploded view showing a first embodiment of the puncture member 260 according to the present disclosure; Figure 20B is a first view showing the first embodiment of the puncture member 260 according to the present disclosure after assembly; Figure 20C is a cross-sectional view showing the first embodiment of the puncture member 260 according to the present disclosure; Figure 20D is a second view showing the first embodiment of the puncture member 260 according to the present disclosure after assembly.

[0507] As described above, referring to Figures 20A and 20B, the puncture member 260 may include a sharp object 270 and a support 280 supporting the sharp object 270. In some examples, the sharp object 270 and the support 280 may be integrally formed. In other examples, the sharp object 270 may be detachably assembled with the support 280. In some examples, the sharp object 270 may have a groove, and the medical device 800 may be placed wholly or partially in the groove. In some examples, the second drive mechanism 40 may act on the support 280. In this case, by placing the medical device 800 wholly or partially in the groove of the sharp object 270, it is convenient to place the medical device 800 at least partially under the skin of the host through the puncture member 260. In some examples, the implantation portion of the sensor 820 may be placed within the groove 274 of the sharp object 270.

[0508] In some examples, the sharp object 270 may include a needle-like portion 272 (see Figure 20A). In some examples, a groove extending along the length of the needle-like portion 272 may be provided on the needle-like portion 272. The medical device 800 may be at least partially disposed within the groove of the sharp object 270. In this case, the sensor 820 may be received within the groove to facilitate the sensor 820 being placed subcutaneously in the host along with the sharp object 270.

[0509] In some examples, the sharp object 270 may include a cap 276 connected to the needle portion 272 (see FIG. 20A). In some examples, the needle portion 272 may be fitted to the support 280 via the cap 276.

[0510] In some examples, referring to FIG20A, the support 280 may include a hole 2821 configured to receive a cap 276, the cap 276 extending through the hole 2821 and fitted into the support 280. In some examples, the support 280 may include a sharps retainer 282 having the hole 2821. In some examples, the cap 276 may be secured to the sharps retainer 282.

[0511] In some examples, the cap 276 may include a second portion 278 and a third portion 279 connected in sequence (see Figure 20C). In some examples, the sharp object 270 may be secured to the support 280 via the third portion 279.

[0512] In some examples, the third portion 279 has a plurality of fingers configured to snap onto the support 280. In some examples, the cap 276 has a tip remote from the sensor control device and an end opposite to the tip, with the plurality of fingers formed at the tip and extending away from the central axis of the tip 270 in a direction from tip to end. Thus, the tip 270 can be secured to the support 280 in a one-way locking manner.

[0513] In some examples, the number of fingers can be 2, 3, 4, 5, or 6, etc.

[0514] In some examples, the third part 279 may be elastic. In some examples, the sharp object fixing part 282 may be elastic.

[0515] In some examples, during assembly, multiple fingers can be compressed in a direction toward the central axis CA, and can return to an expanded posture after the multiple fingers have extended through the hole 2821. This allows them to snap into the support 280.

[0516] In some examples, the sharp object retaining portion 282 may further include a limiting portion 289 configured to inhibit rotation of the sharp object 270 (see Figures 20C and 20D). In some examples, the limiting portion 289 may be formed as a groove restricting circumferential movement of the finger. In some examples, the limiting portion 289 may be formed by two adjacent protrusions to restrict circumferential movement of the finger.

[0517] In some examples, when the sharp object 270 is fitted onto the support 280, the finger can engage with the groove. This prevents the sharp object 270 from rotating.

[0518] Figure 20E is an exploded view showing a second embodiment of the puncture member 260 according to the present disclosure; Figure 20F is a first view showing the assembled second embodiment of the puncture member 260 according to the present disclosure; Figure 20G is a schematic diagram showing the support 280 in the second embodiment of the puncture member 260 according to the present disclosure; Figure 20H is a cross-sectional view showing the second embodiment of the puncture member 260 according to the present disclosure; Figure 20I is a schematic diagram showing a plurality of sharp object fixing arms 2822 in the second embodiment of the puncture member 260 according to the present disclosure; Figure 20J is a second view showing the assembled second embodiment of the puncture member 260 according to the present disclosure. It should be noted that only the differences between the first and second embodiments of the puncture member 260 are described in detail below. The same structures or parts can be referred to the description of the first embodiment, and will not be repeated here. In addition, to illustrate the sharp object 270 and the support 280 more clearly, there is a gap between the sharp object 270 and the support 280 in Figures 20H and 20J, but this should not be interpreted as the sharp object 270 and the support 280 not being able to come into contact.

[0519] As described above, referring to Figures 20E and 20F, the puncture member 260 may include a sharp object 270 and a support 280 for supporting the sharp object 270.

[0520] In some examples, referring to Figures 20E and 20H, the third part 279 may have one or more fingers configured to snap onto the support 280. In some examples, the one or more fingers may be toothed. The fingers may also be referred to as retaining teeth. In some examples, the retaining teeth may have an abutting surface inclined away from the central axis of the tip 270 in the direction from tip to end. Thus, the tip 270 can be secured to the support 280 in a one-way locking manner.

[0521] In some examples, the sharp object retaining portion 282 may have a sharp object retaining arm 2822 (see Figure 20G). In some examples, the sharp object retaining arm 2822 may be resilient. In some examples, during assembly, the retaining teeth may compress the sharp object retaining arm 2822 in a direction away from the central axis CA, and may return to an expanded posture after the retaining teeth have extended through the end of the sharp object retaining arm 2822 away from the hole 2821. Thus, it can be engaged with the support 280.

[0522] In some examples, referring to Figure 20H, the sharp object retaining arm 2822 may be tilted away from the central axis CA in the top-to-bottom direction of the support 280. In this case, the retaining teeth can be made to compress the sharp object retaining arm 2822 and deform it in a direction away from the central axis CA so as to enter the support 280 in the bottom-to-top direction, and after extending through one end of the sharp object retaining arm 2822 away from the hole 2821, the retaining teeth are prevented from leaving the support 280 in the top-to-bottom direction.

[0523] In some examples, referring to Figure 20H, after the sharp object fixing arm 2822 returns to its expanded position, the tip of the sharp object fixing arm 2822 can abut against the bottom surface of the fixing tooth. In some examples, the surface of the sharp object fixing arm 2822 abutting against the fixing tooth can be orthogonal to the central axis. In this case, since the sharp object fixing arm 2822 is inclined away from the central axis CA along the direction from the top to the bottom of the support 280, when the tip of the sharp object fixing arm 2822 abuts against the bottom surface of the fixing tooth, the abutting force exerted by the fixing tooth on the sharp object fixing arm 2822 can cause the sharp object fixing arm 2822 to have a tendency to deform towards the central axis CA, thereby causing the sharp object fixing arm 2822 to compress the third part 279, thereby further improving the stability of the sharp object 270 fixed to the support 280.

[0524] In some examples, referring to FIG20H, the third portion 279 may have a suppressing portion 2792 configured to suppress the wobbling of the sharp object 270. In some examples, the sharp object retaining portion 282 may have a suppressing surface 2823. In some examples, when the sharp object 270 is engaged with the support 280, the suppressing portion 2792 may abut against the suppressing surface 2823. In some examples, the suppressing surface 2823 may have a similar profile to the suppressing portion 2792. This reduces the gap between the third portion 279 and the sharp object retaining portion 282, thereby helping to suppress the wobbling of the sharp object 270.

[0525] In some examples, referring to Figure 20H, the restraining surface 2823 may be inclined away from the central axis CA along the top-to-bottom direction of the support 280. This allows the restraining surface 2823 to limit the depth to which the sharp object 270 enters the support 280.

[0526] In some examples, when the retaining tooth extends through the end of the sharp object retaining arm 2822 away from the hole 2821, the top of the sharp object retaining arm 2822 can abut against the bottom surface of the retaining tooth, and the suppressing surface 2823 can abut against the suppressing part 2792. In this case, after the sharp object 270 is engaged with the support 280, the movement of the sharp object 270 relative to the support 280 in the central axis CA can be restricted, thereby improving the stability of the sharp object 270 fixed to the support 280.

[0527] In some examples, referring to Figure 20I, the number of sharp object retaining arms 2822 can be multiple. This further limits the axial travel of the sharp object 270. In some examples, the number of sharp object retaining arms 2822 can be the same as the number of retaining teeth.

[0528] In some examples, multiple sharp object retaining arms 2822 can be evenly arranged around the third portion 279. In this case, the multiple locking forces applied to the third portion 279 by the multiple sharp object retaining arms 2822 can be in a balanced state. This further suppresses the swaying of the sharp object 270. For example, in Figure 20I, the number of sharp object retaining arms 2822 can be two. The two sharp object retaining arms 2822 can be symmetrically distributed on both sides of the third portion 279.

[0529] In some examples, referring to Figure 20J, there can be multiple limiting portions 289. In some examples, the multiple limiting portions 289 can abut against three planes of the third portion 279 that do not have fixed teeth. Thus, it is possible to suppress the rotation of the sharp object 270.

[0530] In some examples, the second portion 278 can be a structure with a central geometry larger than the diameter of the hole 2821, for example, it can be a cylinder with a diameter larger than the hole 2821. Thus, the second portion 278 can limit the axial travel of the sharp object 270. Furthermore, the engagement of the second portion 278 and the third portion 279 can axially fix the sharp object 270 to the support 280.

[0531] In some examples, the cap 276 may include a first portion 277, a second portion 278, and a third portion 279 connected in sequence. The first portion 277 may be used to mate with the medical device 800.

[0532] Figure 20K is a cross-sectional view showing a third embodiment of the puncture member 260 according to the present disclosure. Figure 20L is a cross-sectional view showing a fourth embodiment of the puncture member 260 according to the present disclosure. Figure 20M is a cross-sectional view showing a fifth embodiment of the puncture member 260 according to the present disclosure. Figure 20N is a cross-sectional view showing a sixth embodiment of the puncture member 260 according to the present disclosure. It should be noted that some identical or similar structures are described above and will not be repeated here.

[0533] In some examples, referring to Figures 20K and 20L, the limiting portion 289 can be a semi-enclosed structure. In some examples, the limiting portion 289 can be at least partially positioned above the third portion 279. This helps to prevent the third portion 279 from excessively extending into the support 280.

[0534] In some examples, the number of first joining structures 27411 can be one or more (see Figures 20K and 20L). For example, the number of first joining structures 27411 can be one, two, three, or four. In some examples, the number of second joining structures 721 can also be one or more. For example, the number of second joining structures 721 can be one, two, three, or four. In some examples, the number of first joining structures 27411 and the number of second joining structures 721 can be equal.

[0535] In some examples, referring to FIG20M, the limiting portion 289 may have a limiting hole 2891. In some examples, the sharp object 270 may extend at least partially into the limiting hole 2891. In some examples, the needle-like object 272 may extend at least partially into the limiting hole 2891. This reduces the wobbling of the sharp object 270 within the support 280.

[0536] In some examples, the limiting hole 2891 can be aligned with the hole 2821.

[0537] In some examples, referring to Figure 20N, the third portion 279 may have a predetermined taper. In some examples, along the central axis CA and towards the proximal end, the sidewalls of the third portion 279 may gradually move away from the central axis CA. This facilitates the fitting of the sharp object 270 to the support 280.

[0538] In some examples, the stiffness of the third portion 279 can be greater than the stiffness of the sharp object fixing portion 282. In some examples, the third portion 279 can have a deformable portion. In some examples, the deformable portion can be formed by the third portion 279 being recessed towards the central axis CA. In this case, during the process of assembling the sharp object 270 onto the support 280, since the third portion 279 is compressed against the sharp object fixing portion 282, the formation of the deformable portion provides space for the sharp object fixing portion 282 to deform under pressure, thereby facilitating the assembly of the sharp object 270 onto the support 280. In some examples, the deformable portion can be a cut formed in the third portion 279.

[0539] In other examples, the stiffness of the third part 279 may also be less than or equal to the stiffness of the sharp object fixing part 282.

[0540] In some examples, the sidewall of the third portion 279 may partially abut against the inner wall of the sharp object fixing portion 282. In some examples, the size of the sidewall of the third portion 279 may be smaller than the size of the inner wall of the sharp object fixing portion 282.

[0541] In some examples, referring to Figure 20N, the third portion 279 may have a limiting flange 2791. In some examples, the limiting flange 2791 may be configured to limit the length of the third portion 279 extending into the support 280.

[0542] In this disclosure, unless otherwise specified, the first embodiment of the puncture member 260 is used as an example for description, but the same description is also applicable to other embodiments of the puncture member 260.

[0543] Figure 21A is an exploded view of a first perspective of the sterilization assembly according to an example of this disclosure. Figure 21B is an exploded view of a second perspective of the sterilization assembly according to an example of this disclosure.

[0544] As described above, during the user's use of the analyte monitoring system 1, the sharp object 270 and the sensor 820 can at least partially penetrate the host's subcutaneous tissue. In some examples, the sharp object 270 and the sensor 820 can be sterilized. In some examples, the sensor 820 can be sterilized using radiation sterilization. Radiation sterilization methods can include, for example, electron beam radiation, gamma ray radiation, X-ray radiation, or a combination thereof. This contributes to the health and safety of the host.

[0545] In some examples, after the sharp object 270 and sensor 820 are sterilized, they can be stored in a sealed space. In this case, the sharp object 270 and sensor 820 can remain in a sterile space until the user uses the analyte monitoring system 1.

[0546] In some examples, referring to Figures 21A and 21B, the analyte monitoring system 1 may include a sharp object 270, a sealing assembly 500, a sealing cap 600, a sensor 820, a base 830, and a cap 700. In some examples, the sharp object 270, sealing assembly 500, sealing cap 600, sensor 820, base 830, and cap 700 may constitute a sterilization assembly. In some examples, the entire sterilization assembly may be sterilized. In some examples, when sterilizing the entire sterilization assembly, components such as the cap 700 may be made of at least a material that allows radiation to pass through. In some examples, suitable materials for making the cap 700 may be non-magnetic metals, thermoplastics, ceramics, rubber, composite materials, or combinations thereof.

[0547] In some examples, the sterilization assembly may have a sealed space. In some examples, the sharp object 270 and the sensor 820 may be at least partially located within the sealed space of the sterilization assembly.

[0548] In some examples, the sharp object 270, sealing assembly 500, sealing cap 600, sensor 820, base 830, and cap 700 can be assembled together to form the aforementioned sealed space.

[0549] Figure 22A is a structural schematic diagram showing a first view of the base 830 according to an example of this disclosure. Figure 22B is a structural schematic diagram showing a second view of the base 830 according to an example of this disclosure.

[0550] In some examples, the applicator 860 may include a base 830 (see Figures 22A and 22B). In some examples, the outline of the base 830 may be generally racetrack-shaped.

[0551] In some examples, the base 830 may include an opening 831. In some examples, the sensor 820 may be supported on the base 830. In some examples, the central axis of the tail 821 of the sensor 820 may extend through the opening 831.

[0552] In some examples, the outline of the opening 831 may be the same as the outline of the first portion 277 of the sharp object 270. This reduces the movement of the sharp object 270 within the opening 831.

[0553] In some examples, the outline of the opening 831 can be approximately racetrack-shaped. In this case, since the outline of the opening 831 is the same as the outline of the first portion 277 of the sharp object 270, it is possible to suppress undesirable rotation of the sharp object 270 in the opening 831.

[0554] In some examples, the outline of the opening 831 may also be a non-circular shape such as a polygon, a square, or a fan.

[0555] In some examples, the opening 831 can be a through hole. This allows the sharp object 270 and the sensor 820 to pass through the opening 831 and extend out of the bottom surface of the base 830, thereby facilitating the implantation of the sharp object 270 and the sensor 820 under the skin of the host.

[0556] In some examples, referring to FIG22A, the base 830 may include a support portion 832. In some examples, the support portion 832 may be a boss. In some examples, the support portion 832 may be configured to support at least a portion of the sensor 820.

[0557] In some examples, referring to Figures 22A and 22B, the base 830 may include a substrate 833. In some examples, a support portion 832 may be disposed on the substrate 833. In some examples, an opening 831 may extend through the support portion 832 and the substrate 833.

[0558] In some examples, referring to Figure 22A, the base 830 may include a mounting portion 834. In some examples, the mounting portion 834 may be disposed on the support portion 832.

[0559] In some examples, the assembly part 834 may also be disposed on the substrate 833.

[0560] In some examples, referring to FIG22A, the base 830 may include a fixing portion 838. In some examples, the fixing portion 838 may be configured to fix the sensor 820. In some examples, the fixing portion 838 may be disposed on the substrate 833. In some examples, the fixing portion 838 may be a protrusion formed on the substrate 833.

[0561] In some examples, referring to Figure 22A, there can be two fixing parts 838. In some examples, the two fixing parts 838 can be arranged opposite each other.

[0562] In other examples, the number of fixing parts 838 may be one. For example, the fixing part 838 may be a fork structure with a groove structure.

[0563] In other examples, the number of fixing parts 838 can be greater than two. For example, the number of fixing parts 838 can be four, five, six, or seven, etc. This allows for more stable fixing of the contact part 823.

[0564] In some examples, referring to FIG22A, the fixing portion 838 may have an inclined surface 8381. In some examples, the inclined surface 8381 may be inclined along the direction from the top end to the bottom end of the fixing portion 838 and toward a direction away from the fixing portion 838. This facilitates the alignment of the slot accommodating the sensor 820 on the electronic device 880 with the sensor 820. (Detailed description follows later)

[0565] Figure 23 is a schematic diagram illustrating the structure of the sensor 820 involved in the example of this disclosure.

[0566] In some examples, referring to Figure 23, medical device 800 may include sensor 820. In some examples, sensor 820 may be configured to generate analyte level information for the host. In some examples, sensor 820 may be partially or completely implanted subcutaneously in the host. In some examples, after being implanted subcutaneously, sensor 820 may react with analytes in subcutaneous tissue fluid to generate analyte level information for the host.

[0567] In some examples, referring to Figure 23, sensor 820 may include a tail 821. In some examples, tail 821 may be used for implantation into a host.

[0568] In some examples, sensor 820 may include a contact 823 for electrical connection (see FIG. 23). In some examples, contact 823 may be configured to connect to electronic device 880. In some examples, contact 823 may have electrical contacts.

[0569] In some examples, referring to FIG. 23, the contact portion 823 and the tail portion 821 of the sensor 820 can form an angle of approximately 90 degrees. This facilitates placing the tail portion 821 into the opening 831 or electrically connecting the contact portion 823 to the electronic device 880 during implantation into the host. In some examples, the angle formed between the contact portion 823 and the tail portion 821 of the sensor 820 can be slightly greater than 90 degrees. This facilitates contacting the tail portion 821 with the needle-like portion 272. In some examples, referring to FIG. 23, the angle between the contact portion 823 and the tail portion 821 of the sensor 820 can be between 0 and 90 degrees.

[0570] In some examples, referring to FIG23, sensor 820 may include a coupling portion 822. In some examples, coupling portion 822 may connect tail portion 821 and contact portion 823. That is, tail portion 821, coupling portion 822 and contact portion 823 may be connected in sequence. Thus, the analyte level signal generated by tail portion 821 can be transmitted to contact portion 823 through coupling portion 822.

[0571] Figure 24 is a schematic diagram showing the sensor 820 disposed on the base 830 according to an example of this disclosure.

[0572] In some examples, referring to Figure 24, the sensor 820 can be mounted on the base 830. This facilitates holding the sensor 820 under the skin of the host.

[0573] In some examples, referring to Figure 24, the sensor 820 may be at least partially located in the opening 831. In some examples, the tail 821 may be at least partially located in the opening 831. In some examples, the tail 821 may extend through the opening 831 and out of the bottom surface of the base 830. This facilitates the at least partial implantation of the sensor 820 under the skin of the host. Furthermore, since the sharp object 270 extends through the opening 831, it facilitates the sharp object 270 to accommodate the tail 821 of the sensor 820 and to carry the tail 821 for implantation into the host.

[0574] In some examples, the tail 821 can be aligned with the opening 831. This further facilitates the reception of the tail 821 by the sharp object 270.

[0575] In some examples, referring to Figure 24, the sensor 820 may be located at least partially outside the opening 831. In some examples, the connecting portion 822 and the contact portion 823 may also be located outside the opening 831.

[0576] In some examples, referring to FIG. 24, the applicator 860 may include a channel 400. In some examples, the channel 400 may extend toward the opening 831. In some examples, referring to FIG. 24, the sensor 820 may pass through the channel 400 and be located at the opening 831. In some examples, the connector 822 may extend through the channel 400.

[0577] In some examples, referring to Figure 24, the channel 400 may be provided on the support portion 832. In some examples, the sensor 820 may enter the opening 831 via the channel 400 provided on the support portion 832.

[0578] In some examples, the channel 400 may have a fixed size that adapts to the connector 822, which may be equal to or similar in size to the connector 822. This minimizes the gap between the connector 822 and the channel 400, thereby facilitating the formation of a seal in the channel 400.

[0579] In some examples, the sealing component 500 may form a seal in the channel 400 or in the direction of extension of the channel 400. In some examples, the sealing component 500 may be disposed in the channel 400. In some examples, the sealing component 500 may be at least partially disposed in the channel 400.

[0580] As described above, the fixing portions 838 can be arranged opposite each other. In some examples, the fixing portions 838 can be symmetrically distributed on both sides of the sensor 820. In some examples, the fixing portions 838 can clamp the contact portion 823. This reduces the shaking of the sensor 820 during assembly.

[0581] Figure 25A is a schematic diagram showing the first embodiment of the sealing cap 600 according to the present disclosure covered by the support portion 832. Figure 25B is a cross-sectional view along section line XX in Figure 25A. Figure 25C is a structural schematic diagram from a first perspective showing the first embodiment of the sealing cap 600 according to the present disclosure. Figure 25D is a structural schematic diagram from a second perspective showing the first embodiment of the sealing cap 600 according to the present disclosure.

[0582] In some examples, referring to FIG25A, the application portion 860 may include a sealing cap 600. In some examples, the sealing cap 600 may cover the base 830 and the sensor 820. In some examples, the sealing cap 600 may cover the support portion 832.

[0583] In some examples, the sealing cap 600 can completely cover the support portion 832. In other words, in some examples, the projection of the sealing cap 600 onto the support portion 832 along the axial direction of the support portion 832 can completely coincide. This improves the structural compactness and facilitates subsequent sealing of the upper interface.

[0584] In some examples, the sealing cap 600 may at least partially cover the channel 400. This helps to form a sealing interface at the channel 400. Additionally, it helps to retain the sensor 820 within the channel 400.

[0585] In some examples, the sealing cap 600 and the support portion 832 can be fixedly connected by one or more methods such as adhesives or ultrasonic welding. This enhances the sealing performance of the sealing cap 600.

[0586] In some examples, referring to Figures 25A and 25B, the sealing cap 600 may have a central hole 610 aligned with the opening 831. In some examples, the central hole 610 may be configured to allow a sharp object 270 to extend through it.

[0587] In some examples, referring to Figures 25B and 25C, the profile of the central hole 610 can be the same as the profile of the opening 831. That is, the profile of the central hole 610 can be the same as the profile of the first portion 277 of the sharp object 270. This allows undesirable rotation of the sharp object 270 within the central hole 610 to be suppressed.

[0588] In other examples, the profile of the central hole 610 may also be different from the profile of the opening 831.

[0589] In some examples, referring to Figure 25D, the sealing cap 600 may have a first notch 620. In some examples, the first notch 620 may be aligned with the channel 400. In some examples, the first notch 620 may at least partially coincide with the channel 400. This allows the connecting portion 822 to pass through the channel 400.

[0590] Additionally, in some examples, channel 400 may also be provided on the sealing cover 600. In some examples, channel 400 may extend toward the central hole 610. In some examples, channel 400 may be provided on the side of the sealing cover 600 near the support portion 832.

[0591] As described above, the base 830 may include an assembly portion 834. In some examples, referring to FIG. 22A, the assembly portion 834 may have a first pocket 8341. In some examples, referring to FIG. 22A, the first pocket 8341 may surround the opening 831. In some examples, the first pocket 8341 may be an annular groove.

[0592] In some examples, referring to Figure 25B, the assembly 834 can mate with the sealing cap 600. In some examples, the sealing cap 600 can be received at least partially in the first bag 8341.

[0593] In some examples, adhesive may be injected into the first bag 8341 before the sealing cap 600 is assembled onto the assembly portion 834. This helps to seal the interface between the assembly portion 834 and the sealing cap 600.

[0594] In some examples, referring to Figure 25B, a gap may exist between the portion of the sealing cap 600 that receives the first bag 8341 and the bottom of the first bag 8341. In this case, by leaving a certain flow space for the adhesive between the sealing cap 600 and the first bag 8341, it is possible to facilitate the flow of the adhesive to fill the gap between the parts, thereby helping to seal the interface between the assembly 834 and the sealing cap 600.

[0595] In some examples, referring to Figure 22A, the first bag 8341 can be in communication with channel 400. Thus, the adhesive can seal channel 400. In some examples, adhesive can be injected into channel 400 to seal it.

[0596] In some examples, referring to FIG25A, the base 830 may have a first limiting portion 835. In some examples, the sealing cap 600 may have a second limiting portion 650. In some examples, during the process of assembling the sealing cap 600 into the assembly portion 834, the first limiting portion 835 may be aligned with the second limiting portion 650. This allows for more accurate assembly of the sealing cap 600 into the assembly portion 834.

[0597] In some examples, referring to Figure 25A, a first limiting portion 835 may be provided on the assembly portion 834, and a second limiting portion 650 may be provided on the sealing cover 600. In some examples, the shape of the first limiting portion 835 may be complementary to the shape of the second limiting portion 650. For example, the first limiting portion 835 may be a groove, and the second limiting portion 650 may be a protrusion.

[0598] In addition, in some examples, the first limiting part 835 may also be provided on the substrate 833, and the second limiting part 650 may also be provided on the sealing cover 600.

[0599] In some examples, when the first limiting portion 835 is aligned with the second limiting portion 650, the first notch 620 can be aligned with the connecting portion 822. In this case, by aligning the first limiting portion 835 and the second limiting portion 650, the first notch 620 can be aligned with the connecting portion 822, thereby facilitating the assembly of the sealing cap 600.

[0600] In some examples, referring to FIG25A, the first limiting portion 835 may abut against the second limiting portion 650. In some examples, the first limiting portion 835 may abut against the second limiting portion 650 in the circumferential direction of the assembly portion 834. This prevents rotation of the sealing cap 600 relative to the assembly portion 834, thereby reducing the risk of damage to the sensor 820 due to rotation of the sealing cap 600.

[0601] Figure 26 is a schematic diagram illustrating the structure of the sharp object 270 involved in the example of this disclosure.

[0602] As described above, referring to Figure 26, the analyte monitoring system 1 may include a sharp object 270. In some examples, the sharp object 270 may be configured to implant the sensor 820 at least partially under the skin of the host.

[0603] In some examples, referring to Figure 26, the sharp object 270 may include a needle-like portion 272. This facilitates the insertion of the sharp object 270 into the tissue.

[0604] In some examples, referring to FIG26, the sharp object 270 may include a groove 274. In some examples, the groove 274 may be configured to receive a tail portion 821. In some examples, the groove 274 may be provided on the needle portion 272. In some examples, the groove 274 may extend along the length direction of the needle portion 272.

[0605] In some examples, the opening of the slot 274 can face the tail 821. This facilitates the entry of the tail 821 into the slot 274.

[0606] In some examples, referring to Figure 26, the sharp object 270 may include a cap 276. In some examples, the cap 276 may be at least partially located at the opening 831.

[0607] In some examples, referring to FIG26, the cap 276 may include a first portion 277. In some examples, the outer contour of the first portion 277 is substantially the same as the inner contour of the opening 831. As described above, the contour of the opening 831 may be substantially racetrack-shaped. In some examples, the contour of the first portion 277 may also be substantially racetrack-shaped. Thus, unwanted rotation of the first portion 277 within the opening 831 can be suppressed.

[0608] In some examples, the outline of the first part 277 can also be a non-circular shape such as a polygon, a square, or a fan.

[0609] In some examples, referring to Figure 26, the cap 276 may include a second portion 278. In some examples, the second portion 278 may be configured to secure the first sealing element 510.

[0610] In some examples, referring to Figure 26, the cap 276 may include a third portion 279. In some examples, the third portion 279 may be configured to secure the sharp object 270 to the support 280.

[0611] In some examples, referring to Figure 26, the needle-like portion 272 can be connected to the cap portion 276. In some examples, the needle-like portion 272 can be fixed to the cap portion 276. In some examples, the cap portion 276 can hold the needle-like portion 272. This allows the needle-like portion 272 to more stably carry the sensor 820 into the tissue.

[0612] In some examples, the needle-like portion 272 may penetrate the cap portion 276. In some examples, the needle-like portion 272 may be fixed to the first portion 277 of the cap portion 276.

[0613] In some examples, the sharp object 270 may have a slotted portion 275 (see Figure 26). In some examples, the slotted portion 275 may be located on the side of the first portion 277 near the tail 821. This facilitates the tail 821 entering the slotted portion 275.

[0614] In some examples, the opening of the slot 274 may face the slotted portion 275. In some examples, the slot 274 may communicate with the slotted portion 275. This allows the tail portion 821 to easily enter the slot 274 through the slotted portion 275.

[0615] Figure 27 is a schematic diagram showing the structure of the first sealing element 510 involved in the example of this disclosure.

[0616] In some examples, referring to FIG27, the sealing assembly 500 may include a first sealing element 510. In some examples, the first sealing element 510 may be configured to seal the opening 831. In some examples, the first sealing element 510 may be configured to seal the upper interface of the opening 831.

[0617] In some examples, referring to Figures 21A or 21B, the first sealing element 510 may be disposed between the sharp object 270 and the sealing cap 600. In some examples, the first sealing element 510 may seal the interface between the sharp object 270 and the sealing cap 600. In some examples, the first sealing element 510 may seal the central hole 610. In some examples, the first sealing element 510 may seal the opening 831 by sealing the central hole 610. It should be noted that since there is already a sealing interface between the sealing cap 600 and the base 830, the upper interface of the central hole 610 can also be regarded as the upper interface of the opening 831, and sealing the opening 831 is also equivalent to sealing the central hole 610.

[0618] In some examples, the first sealing element 510 may be made of an elastic material. In some examples, the first sealing element 510 may be made of materials such as silicone resin, thermoplastic elastomer (TPE), polytetrafluoroethylene, or rubber. This improves the sealing performance of the first sealing element 510.

[0619] Figure 28A is a schematic diagram showing the sharp object 270 of the present disclosure assembled on the base 830 from a first perspective. Figure 28B is a schematic diagram showing the sharp object 270 of the present disclosure assembled on the base 830 from a second perspective. Figure 28C is a schematic diagram showing the depth-limiting portion 2742 of the present disclosure abutting against the sealing cover 600.

[0620] In some examples, referring to Figures 28A and 28B, the sharp object 270 may be fitted onto the base 830. In some examples, the sharp object 270 may extend through the opening 831. In some examples, the sharp object 270 may be at least partially located in the opening 831.

[0621] In some examples, referring to Figures 28A and 28B, the first portion 277 may extend at least partially into the opening 831. This facilitates coupling of the sharp object 270 with the cap 700.

[0622] In some examples, referring to Figures 28A and 28B, the needle-like portion 272 may extend at least partially into the opening 831. This facilitates the insertion of the needle-like portion 272 into the subcutaneous tissue of the host.

[0623] In some examples, referring to Figure 28B, the sharp object 270 may be configured to accommodate at least a portion of the sensor 820. In some examples, the sharp object 270 may accommodate the tail 821 of the sensor 820. In some examples, the sharp object 270 may also be configured to penetrate tissue carrying at least a portion of the sensor 820. In some examples, the sharp object 270 may penetrate tissue carrying the tail 821. This facilitates the implantation of the sensor 820 into the host.

[0624] As described above, the groove 274 can be configured to receive the tail 821. In some examples, the needle-like portion 272 with the groove 274 can also be configured to carry the tail 821 into the tissue. In this case, receiving the tail 821 through the groove 274 facilitates the needle-like portion 272 carrying the tail 821 into the tissue.

[0625] In some examples, referring to Figure 28A, the first sealing element 510 may be fitted onto the cap 276. In some examples, both ends of the first sealing element 510 may be embedded in the cap 276. In this case, the risk of the first sealing element 510 falling off the cap 276 when the sharp object 270 moves is reduced.

[0626] As described above, the cap 276 may include a second portion 278. In some examples, a first sealing element 510 may be fitted onto the second portion 278. In some examples, the first sealing element 510 may have a first hole 511 (see FIG. 26). In some examples, a sharp object 270 may pass through the first hole 511 to fit the first sealing element 510 onto the second portion 278.

[0627] In some examples, the first sealing element 510 may be fitted over the second portion 278 in a covering manner. In some examples, the outer contour of the second portion 278 may be the same as the inner contour of the first sealing element 510. In some examples, the second portion 278 may be an annular protrusion on the cap 276, and the first sealing element 510 may be a collar with a vertical cross-section in the shape of a C (see Figures 26 and 27).

[0628] In some examples, the size of the first sealing element 510 may be slightly smaller than the size of the second portion 278. This allows the first sealing element 510 to fit more tightly onto the second portion 278.

[0629] In some examples, see Figure 28A, one side of the first sealing element 510 can engage with the sharp object 270, and the other side of the first sealing element 510 can engage with the sealing cap 600.

[0630] In some examples, referring to Figure 28A, the first sealing element 510 may surround the central hole 610. This facilitates sealing of the central hole 610 by the first sealing element 510. In some examples, the first sealing element 510 may be annular.

[0631] In some examples, the first sealing element 510 may be a sealing gasket or an O-ring.

[0632] In some examples, referring to Figure 28A, a sharp object 270 can enter the opening 831 through the first hole 511. In some examples, the first hole 511 can be aligned with the opening 831. This allows the sharp object 270 to pass through the first hole 511 and enter the opening 831.

[0633] In some examples, the sharp object 270 can apply pressure to the first sealing element 510. In some examples, the sharp object 270 can press the first sealing element 510 against the sealing cap 600 to deform the first sealing element 510. In some examples, the first sealing element 510 can deform under pressure to seal the interface between the sharp object 270 and the sealing cap 600. In some examples, the first sealing element 510 surrounding the opening 831 can deform under pressure to seal the upper interface of the opening 831. This improves the sealing performance of the first sealing element 510.

[0634] In some examples, referring to Figures 26 and 28C, the cap portion 276 may include a depth-limiting portion 2742. In some examples, the depth-limiting portion 2742 may be configured to limit the depth of the insertion opening 831 of the first portion 277. In some examples, the depth-limiting portion 2742 may be disposed within the first portion 277. In some examples, the depth-limiting portion 2742 may protrude beyond the first portion 277.

[0635] In other examples, the depth limit 2742 may also be located on the bottom surface of the second portion 278 and protrude outward from the second portion 278.

[0636] In some examples, referring to Figure 28C, when the first portion 277 extends through the opening 831 and out of the base 830, the depth-limiting portion 2742 can abut against the sealing cap 600. This helps to more stably mount the sharp object 270 onto the base 830.

[0637] In other examples, the depth limit 2742 may also abut against the support 832.

[0638] It should be noted that when the sharp object 270 is assembled on the base 830, since the sharp object 270 and the sealing cover 600 are connected through the first sealing element 510, that is, the connection between the sharp object 270 and the sealing cover 600 is an elastic connection, and the sharp object 270 will apply pressure to the first sealing element 510, if the pressure applied to the first sealing element 510 is uneven, different positions of the first sealing element 510 will have different degrees of deformation, which will not be able to provide stable support for the sharp object 270, and may cause the sharp object 270 to shake. Therefore, by the depth limiting part 2742 abutting against the sealing cover 600, the sharp object 270 can be provided with rigid support, reducing the shaking of the sharp object 270.

[0639] In some examples, the thickness of the first sealing element 510 before compression can be greater than the thickness of the depth limiting portion 2742. This helps to ensure that the first sealing element 510 is sufficiently compressed to perform its sealing function.

[0640] In some examples, the depth limiting portion 2742 may be integrally formed with the first portion 277 or the second portion 278. Additionally, in some examples, the depth limiting portion 2742 may be detachably connected to the first portion 277 or the second portion 278.

[0641] Figure 28D is a schematic diagram illustrating a second embodiment of the base 830 according to an example of this disclosure. Figure 28E is an exploded view showing the second embodiment of the base 830 according to an example of this disclosure, along with the sealing cover 600 and the sensor 820. Figure 28F is an assembly schematic diagram showing the second embodiment of the base 830 according to an example of this disclosure, along with the sealing cover 600 and the sensor 820. Figures 28E and 28F also show schematic diagrams of the second embodiment of the sealing cover 600, and the sensor 820 in Figures 28E and 28F has been simplified.

[0642] As described above, the base 830 may include an opening 831 and a support 832. The central axis of the tail portion 821 of the sensor 820 may extend through the opening 831, and the support 832 may be configured to support at least a portion of the sensor 820.

[0643] In some examples, referring to FIG28D, the support portion 832 may include a first support portion 8321. In some examples, the first support portion 8321 may be configured to support at least a portion of the sensor 820.

[0644] As described above, the application portion 860 may include a sealing cap 600. In some examples, referring to FIG. 28D, the support portion 832 may include a second support portion 8322. In some examples, the second support portion 8322 may cooperate with the first support portion 8321 to restrict the position of the sealing cap 600. In some examples, the support portion 832 may not include the second support portion 8322. That is, the function of restricting the position of the sealing cap 600 can be achieved by relying solely on the first support portion 8321.

[0645] In some examples, the sealing cap 600 may be disposed around the opening 381. In some examples, the sealing cap 600 may have a central hole 610 aligned with the opening 831. In some examples, the size of the central hole 610 may match the size of the opening 381. Thus, the sealing cap 600 can be stably disposed around the opening 831.

[0646] Figure 28G is a schematic diagram illustrating a second embodiment of the sealing cap 600 according to an example of this disclosure.

[0647] In some examples, the sensor 820 can be mounted to the base 830 via a sealing cover 600. Specifically, in some examples, the sealing cover 600 can be mounted to the base 830, and the sensor can be mounted to the sealing cover 600.

[0648] In some examples, referring to FIG28D, the base 830 may have a first limiting portion 835. In some examples, the first limiting portion 835 may be configured to restrict the movement of the sealing cap 600, for example, to restrict the circumferential movement of the sealing cap 600. This allows the sealing cap 600 to be stably positioned on the base 830.

[0649] In some examples, referring to FIG28E, the sealing cap 600 may include a second limiting portion 650. In some examples, the second limiting portion 650 may be configured to cooperate with the first limiting portion 835 to fix the position of the sealing cap 600.

[0650] In some examples, referring to FIG28D, the first limiting portion 835 may include a first limiting feature 8351 and a third limiting feature 8352. In some examples, the first limiting feature 8351 and the third limiting feature 8352 may cooperate to form a recessed area. In some examples, the second limiting portion 650 may match the aforementioned recessed area to stably position the sealing cap 600 on the base 830.

[0651] In some examples, referring to FIG28E, the second limiting portion 650 may include a second limiting feature 655 that matches the aforementioned recessed region.

[0652] In some examples, a first slot 651 and a second slot 652 may be present on both sides of the second limiting feature 655. In some examples, the first slot 651 may match the first limiting feature 8351, and the second slot 652 may match the third limiting feature 8352. This improves the stability of the sealing cover 600 when it is disposed on the base 830.

[0653] As described above, the sealing cap 600 may have a first notch 620. In some examples, referring to FIG28E, the first notch 620 may be a through structure formed in the sidewall of the sealing cap 600. In some examples, the projection of the first notch 620 along the vertical direction may coincide with the projection of the second limiting portion 650.

[0654] In some examples, the first notch 620 may be configured to allow the sensor 820 to pass through. In some examples, the sensor 820 may be fitted to the sealing cap 600 through the first notch 620.

[0655] In some examples, referring to Figure 28E, the sealing cap 600 may include a first pressing feature 653 and a second pressing feature 654. In some examples, the engagement of the first pressing feature 653 and the second pressing feature 654 may form a sealing interface for the sensor 820.

[0656] In some examples, the sealing cap 600 can be an elastic structure. This facilitates sealing of multiple interfaces. In some examples, the sealing cap 600 can be made of an elastic material. In some examples, the sealing cap 600 can be made of materials such as silicone resin, thermoplastic elastomer (TPE), polytetrafluoroethylene, or rubber. This improves the sealing performance of the sealing cap 600.

[0657] In some examples, there may be a gap between the first pressing feature 653 and the second pressing feature 654. That is, the first pressing feature 653 and the second pressing feature 654 may not be a continuous structure.

[0658] In some examples, under the action of external force, the first pressing feature 653 and the second pressing feature 654 can be pressed against each other to expose the gap between them. In some examples, the sensor 820 can be fitted to the first notch 620 along the gap between the first pressing feature 653 and the second pressing feature 654. This facilitates the assembly of the sensor 820.

[0659] In some examples, the sealing interface of the sensor 820 can be formed by the interaction between the first pressing feature 653 and the second pressing feature 654. In some examples, the first pressing feature 653 and the second pressing feature 654 can interact in their natural state. In other words, the first pressing feature 653 and the second pressing feature 654 can interact without the cooperation of other components. This allows the formation of a sealing interface for the sensor 820, providing good watertightness for the electronic connection structure of the sensor 820.

[0660] In some examples, the first pressing feature 653 may at least partially cover the first notch 620. In some examples, the second pressing feature 654 may at least partially cover the first notch 620.

[0661] In some examples, there may be no gap between the first pressing feature 653 and the second pressing feature 654. That is, the first pressing feature 653 and the second pressing feature 654 may be a continuous structure. In this case, the sensor 820 can also be assembled to the sealing cover 600 by passing the sensor 820 laterally through the first notch 620.

[0662] In some examples, a boss may be formed on the substrate 833. In some examples, referring to FIG28D, the opening 831 may be a hollow structure penetrating the boss on the substrate 833. In some examples, the base 830 may have a second notch 6201. In some examples, the second notch 6201 may be formed on the aforementioned boss.

[0663] In some examples, the position of the second notch 6201 matches the position of the first notch 620. Thus, the sensor 820 can extend through the opening 831.

[0664] As described above, the application portion 860 may include a channel 400. In some examples, referring to FIG28D, the channel 400 may extend through the first support portion 8321 and communicate with the recessed area formed by cooperating with the first limiting feature 8351 and the third limiting feature 8352. In some examples, the channel 400 may extend beyond the side of the first support portion 8321 away from the hollow portion 831. This allows for a more stable mounting of the sensor 820.

[0665] In some examples, the sealing cover 600 can be assembled onto the base 830 first, and then the sensor 820 can be assembled onto the sealing cover 600. In some examples, the sensor 820 can be assembled onto the sealing cover 600 first, and then the sealing cover 600 with the sensor 820 assembled onto the base 830.

[0666] Referring back to Figure 27, as described above, the sealing assembly 500 may include a first sealing element 510. In some examples, in this embodiment, since the sealing cap 600 can be an elastic structure, the sealing cap 600 itself can function as the first sealing element 510. Therefore, in this embodiment, the sterilization assembly may not include the first sealing element 510. That is, the sharp object 270 can directly abut against the sealing cap 600 to achieve a seal at the upper interface.

[0667] In some examples, the side of the sealing cap 600 away from the base 830 can be a flat surface. That is, the side of the sealing cap 600 near the top cover 840 can be a flat surface. In this case, the sealing cap 600 and the top cover 840 can also help seal the interface between the top cover 840 and the sealing cap 600.

[0668] In some examples, the side of the sealing cap 600 near the upper cover 840 may have an annular groove that matches the annular flange 630 of the upper cover 840 (see Figure 25C). In some examples, the height of the annular flange 630 of the upper cover 840 may be no less than the depth of the aforementioned annular groove. This improves the sealing performance of the interface between the upper cover 840 and the sealing cap 600.

[0669] In some examples, the annular flange 630 can be a continuous flange, and the matching annular groove can be a continuous groove. In some examples, the annular flange 630 can be a discontinuous flange, and the matching annular groove can be a discontinuous groove.

[0670] In some examples, the first pressing feature 653 may have a protrusion extending beyond the aforementioned flat surface. In some examples, the second pressing feature 654 may have a protrusion extending beyond the aforementioned flat surface.

[0671] In some examples, the cover 840 may have a groove that matches the protrusion of the first pressing feature 653 protruding from the flat surface. In some examples, the cover 840 may have a groove that matches the protrusion of the second pressing feature 654 protruding from the flat surface. In some examples, the size of the groove may not be larger than the size of the protrusion. In this case, when the cover 840 is coupled to the base 830, the interaction between the first pressing feature 653 and the second pressing feature 654 can be further improved, thereby further improving the sealing performance.

[0672] It is understood that, except for the differences already clearly stated above, all structures, positional relationships, material selections, process parameters and interconnection methods disclosed in the first embodiment of the base 830 are applicable to this embodiment. Even if they are not repeated in this embodiment, they should not be interpreted as limiting the scope of protection of this embodiment.

[0673] It is understood that, apart from the distinguishing features described above, all other structural parts of this embodiment can adopt the corresponding design disclosed in the first embodiment of the base 830 and can achieve the same function. To avoid repetition, these similarities will not be described one by one.

[0674] Figure 29A is a structural schematic diagram of the cap 700 according to an example of this disclosure. Figure 29B is a cross-sectional view of the cap 700 of Figure 29A according to an example of this disclosure along the YY section line.

[0675] As described above, referring to Figure 29A, the analyte monitoring system 1 may include a cap 700. In some examples, the cap 700 may be configured to receive a tail portion 821. In some examples, the cap 700 may also be configured to seal an opening 831. In some examples, the cap 700 may be mounted on a base 830.

[0676] In some examples, referring to Figure 29A, the cap 700 may include a mating platform 740. In some examples, the mating platform 740 may be part of the bottom cap 770. In some examples, the cap 700 may be coupled to the housing 10 via the mating platform 740. In some examples, the mating platform 740 may be embedded in the proximal end of the housing 10.

[0677] In some examples, when the cap 70 is coupled to the housing 10, the first engagement feature 191 may surround the engagement platform 740.

[0678] In some examples, the mating base 740 may be elastic. In some examples, the mating base 740 may include an elastic wall 741. In some examples, the mating portion 720 may be disposed on the wall 741. In some examples, the elasticity of the wall 741 can be changed by varying its thickness. For example, the elasticity of the wall 741 can be increased by decreasing its thickness. In this case, since the first engagement feature 191 is a flat thread and the engagement portion 2741 is a helical thread, when the cap 700 is screwed on, the travel distance of the mating portion 720 in the direction of the central axis CA is different from the travel distance of the mating base 740. This causes deformation at the connection between the mating portion 720 and the mating base 740. By adjusting the elasticity of the wall 741 by changing its thickness, the connection between the mating portion 720 and the mating base 740 can be made more easily deformable, thereby facilitating the decoupling of the mating portion 720 and the engagement portion 2741.

[0679] In some examples, referring to Figure 29A, the cap 700 may include a second rib 750. In some examples, the second rib 750 may be located on the side of the mating platform 740. In this case, the second rib 750 reduces the force required to relatively screw the housing 10 and the cap 700 by making the contact between the housing 10 and the mating platform 740 a line contact, thereby facilitating the decoupling of the housing 10 and the cap 700. In some examples, the second rib 750 may surround the mating platform 740. In some examples, there may be multiple second ribs 750.

[0680] In some examples, referring to Figure 29B, the cap 700 may have a chamber 710. In some examples, the chamber 710 may be configured to receive a tail 821. In some examples, the tail 821, the cap 276, and the needle 272 may be at least partially located in the chamber 710.

[0681] In some examples, referring to Figure 29B, the cap 700 may include a desiccant 760. In some examples, the desiccant 760 may be located in the chamber 710. This facilitates keeping the chamber 710 dry.

[0682] In some examples, desiccant 760 may be contained in chamber 790 of bottom cover 770 (see Figure 29B). Specifically, cap 700 may also include base plate 772 that engages with mating platform 740. Mating platform 740 and base plate 772 may mate to form chamber 790 (see Figure 29B). In some examples, chamber 710 and chamber 790 may be in communication.

[0683] In some examples, the base plate 772 can be connected to the mating platform 740. In some examples, the base plate 772 and the mating platform 740 can be fixedly connected by one or more methods such as adhesives, ultrasonic welding, etc. This helps to seal the chamber 710.

[0684] In some examples, the base plate 772 may be made of a transparent material. In this case, after the cap 700 is fitted onto the base 830, the base plate 772 makes it easy to confirm whether the sensor 820 is accommodated in the slot 274.

[0685] Figure 29C is a structural schematic diagram illustrating another embodiment of the cap 700 according to the present disclosure example. Figure 29D is a cross-sectional view of the cap 700 of Figure 29C according to the present disclosure example along the ZZ section line.

[0686] In some examples, the second engagement feature 791 may be elastic. In some examples, the second engagement feature 791 may be elastic in a direction substantially orthogonal to the central axis CA. This facilitates the engagement of the second engagement feature 791 with the first engagement feature 191. As mentioned above, in some examples, the second engagement feature 791 may be a spring arm (see FIG. 29C).

[0687] In some examples, the second engagement feature 791 may tend to contract toward the central axis CA in the direction from proximal to distal.

[0688] In some examples, during assembly, the second engagement feature 791 can be compressed in a direction toward the central axis CA, and after the second engagement feature 791 extends past the engaging portion 1941 of the assembly groove 194, it can return to an expanded posture. Thus, it can engage with the first engagement feature 191.

[0689] In some examples, referring to FIG29C, the cap 700 may include a limiting ridge 793. Referring back to FIG15E, the housing 10 may have a confined groove 153. In some examples, the confined groove 153 may be provided in the first housing 100 or the second housing 140. In some examples, the limiting ridge 793 may be configured to couple with the confined groove 153 to suppress relative rotation between the cap 700 and the housing 10.

[0690] Taking the confined groove 153 provided in the second housing 140 as an example, the limiting ridge 793 can be coupled with the confined groove 153 to suppress the relative rotation between the cap 700 and the second housing 140.

[0691] In some examples, during the coupling of the cap 700 to the housing 10, the second engagement feature 791 can compress the engagement portion 1941 and enter the first engagement feature 191. In some examples, after the second engagement feature 791 compresses the engagement portion 1941 and enters the first engagement feature 191, the limiting ridge 793 can couple with the confined groove 153. In some examples, the limiting ridge 793 can couple with the confined groove 153 (see FIG. 5D) to confine the second engagement feature 791 to the end of the first engagement feature 191 near the mounting groove 194. This helps to prevent the cap 700 from decoupling from the housing 10 before user use.

[0692] In some examples, referring to Figure 5E, during the decoupling of the cap 700 from the housing 10, the limiting ridge 793 and the confined groove 153 can be decoupled. In some examples, the limiting ridge 793 and the confined groove 153 can move relative to each other so that the limiting ridge 793 disengages from the confined groove 153.

[0693] In some examples, a release space 794 (see Figure 5E) can be provided along the movement path of the limiting ridge 793, allowing the limiting ridge 793 to move freely. The release space 794 can be formed by the housing 10 and the cap 700. The limiting ridge 793 can enter the release space 794 after disengaging from the confined groove 153. In some examples, the distance between the housing 10 and the cap 700 can be variable; for example, the distance between the housing 10 and the cap 700 at the confined groove 153 and the limiting ridge 793 can be smaller than the distance at the release space 794. This allows the limiting ridge 793 to be no longer restricted in position after disengaging from the confined groove 153, thus facilitating relative rotation.

[0694] In some examples, the number of limiting ridges 793 can be equal to the number of restricted slots 153. In some examples, the number of limiting ridges 793 and restricted slots 153 can be one. In this case, if the cap 700 and the second housing 140 are not aligned, the size of the portion of the second housing 140 that contacts the limiting ridge 793 during assembly will be smaller than the size of the portion of the cap 700 with the limiting ridge 793, causing the cap 700 to fail to be assembled to the second housing 140. By setting the number of limiting ridges 793 and restricted slots 153 to one, the cap 700 can be assembled to the second housing 140 in a unique orientation.

[0695] In some examples, the dimensions of the limiting ridge 793 and the confined groove 153 can be matched. For example, the dimensions of the limiting ridge 793 and the confined groove 153 can be the same or similar. This improves the tightness of the coupling between the limiting ridge 793 and the confined groove 153.

[0696] In some examples, referring to Figure 29B, the cap 700 may have a structure protruding toward the chamber 710 for securing the desiccant 760, which may be annular to fit over the protruding structure.

[0697] In some examples, referring to Figure 29D, the cap 700 may have a fifth retaining portion 794 configured to hold the desiccant 760. The desiccant 760 may have a fifth locking portion 761, which may be formed on the surface of the desiccant 760.

[0698] In some examples, during the assembly of the desiccant 760, the fifth retaining part 794 can be aligned with the fifth locking part 761.

[0699] Figure 30A is a schematic diagram showing a first view of the cap 700 assembled with the base 830 according to an example of this disclosure. Figure 30B is a schematic diagram showing a second view of the cap 700 assembled with the base 830 according to an example of this disclosure. Figure 30C is a cross-sectional view of the sterilization assembly according to an example of this disclosur...

Claims

1. An application device for applying a monitoring device to a host, characterized in that: The monitoring device includes an on-body unit and sensors. The application device includes a housing, an auxiliary mechanism releasably held in the housing, and a drive mechanism. The auxiliary mechanism includes a moving body for accommodating the monitoring device and a puncture member. The housing has a proximal end that is close to the host during operation and a distal end that is far from the host. The puncture member includes an engagement portion that extends out of the bottom of the suprabody unit in a standby state, and the puncture member is configured to place the sensor at least partially under the skin of the host. The drive mechanism applies force to the auxiliary mechanism toward the proximal end. The application device includes a first triggering mechanism disposed in the travel path of the auxiliary mechanism. After being released by the housing, the auxiliary mechanism moves toward the proximal end under the action of the drive mechanism. During the process of the auxiliary mechanism approaching the proximal end, the first triggering mechanism causes the engagement portion to move relative to the suprabody unit so that the engagement portion does not protrude from the bottom of the suprabody unit.

2. The application device according to claim 1, characterized in that, Throughout the application of the auxiliary mechanism, the bottom of the joint does not protrude from the proximal end of the housing.

3. The application device according to claim 1, characterized in that, The first triggering mechanism is triggered when the bottom of the joint moves to the proximal end of the housing or before the bottom of the joint moves to the proximal end of the housing.

4. The application device according to claim 1, characterized in that, The puncture member is releasably held in the moving body, and the first triggering mechanism is disposed on the travel path of the puncture member, causing the moving body to release the puncture member as the moving body and the puncture member approach the proximal end together.

5. The application device according to claim 4, characterized in that, Before the oncounit is applied to the host, the puncture member is released in advance so that the puncture member assists in placing the sensor at least partially under the host in an orientation in which the joint does not protrude from the bottom of the oncounit.

6. The application device according to claim 4, characterized in that, The moving body includes a retaining part, and the puncture member includes a locking part that is releasably interlocked with the retaining part.

7. The application device according to claim 6, characterized in that, The application device further includes a second drive mechanism that applies force to the puncture member toward the distal end. When the puncture member is released by the moving body, the puncture member moves toward the distal end under the action of the second drive mechanism.

8. The application device according to claim 7, characterized in that, The moving body holds the puncture member in segments. The application device also includes a second triggering mechanism disposed on the travel path of the puncture member. The first triggering mechanism causes the puncture member to be initially released by the moving body so that the joint does not protrude from the bottom of the body unit. The second triggering mechanism causes the puncture member to be released a second time by the moving body. The puncture member that is released a second time leaves the host under the action of the second driving mechanism.

9. The application device according to claim 8, characterized in that, The retaining portion has a first retaining surface and a second retaining surface facing the proximal end. In a standby state, the locking portion contacts and is restricted by the first retaining surface. After the first triggering mechanism is invoked, the locking portion separates from the first retaining surface, and the puncture member moves to contact the second retaining surface and is restricted by the second retaining surface under the action of the second driving mechanism. After the second triggering mechanism is invoked, the locking portion separates from the second retaining surface, and the puncture member continues to move toward the distal end to leave the host under the action of the second driving mechanism.

10. The application device according to claim 6 or 8, characterized in that, The first triggering mechanism includes a protruding structure disposed on the travel path of the puncture member. The protruding structure of the first triggering mechanism is referred to as the first protruding structure. When the first triggering mechanism is invoked, the first protruding structure acts on the locking part or the retaining part to deform it and separate the locking part from the retaining part.

11. The application device according to claim 10, characterized in that, The application device includes a second triggering mechanism disposed on the travel path of the puncture member. The second triggering mechanism includes a protruding structure disposed on the travel path of the puncture member. The protruding structure of the second triggering mechanism is referred to as the second protruding structure. When the second triggering mechanism is invoked, the second protruding structure acts on the locking part or the retaining part to deform it and separate the locking part from the retaining part.

12. The application device according to claim 11, characterized in that, Compared to the second protruding structure, the deformation of the locking part or the retaining part is smaller when the first protruding structure acts on the locking part or the retaining part.

13. The application device according to claim 11, characterized in that, Both the first protruding structure and the second protruding structure are formed on the inner wall of the housing and protrude toward the central axis of the application device.

14. The application device according to claim 13, characterized in that, Compared to the end of the first protruding structure, the end of the second protruding structure is closer to the central axis of the application device.

15. The application device according to claim 13, characterized in that, The first protruding structure and the second protruding structure are sequentially formed on the inner wall of the housing along a direction from the distal end to the proximal end.

16. The application device according to claim 11, characterized in that, The moving body has a cut in a direction generally along the central axis of the application device. The first holding surface and the second holding surface are arranged adjacent to the cut. The first protruding structure and the second protruding structure protrude toward the central axis through the cut. The locking part includes an arm extending in a direction generally along the central axis and a protrusion linked to the arm and protruding away from the central axis in a direction generally orthogonal to the central axis. The protrusion of the locking part passes through the cut to keep the puncture member in a held state.

17. The application device according to claim 16, characterized in that, When the first triggering mechanism is invoked, the arm of the locking part is pressed towards the central axis by the first protruding structure, causing the protrusion of the locking part to leave the first retaining surface to initially release the puncture member; When the second triggering mechanism is invoked, the arm of the locking part is pressed towards the central axis by the second protruding structure, causing the protrusion of the locking part to leave the second retaining surface to release the puncture member for a second time.

18. The application device according to claim 16, characterized in that, The puncture member includes a sharp object and a support seat releasably held in the moving body and supporting the sharp object, the engagement portion being formed on the sharp object and the locking portion being formed on the support seat.

19. The application device according to claim 1, characterized in that, As the auxiliary mechanism approaches the proximal end, the first triggering mechanism actuates the monitoring device to move relative to the joint and a distance relative to the joint toward the proximal end so that the joint does not protrude from the bottom of the body unit.

20. The application device according to claim 1, characterized in that, As the auxiliary mechanism approaches the proximal end, the first triggering mechanism actuates the needle handle to move relative to the monitoring device and a distance relative to the monitoring device toward the distal end so that the engagement portion does not protrude from the bottom of the body unit.

21. The application device according to claim 1, characterized in that, The application device further includes a cap having an inner chamber, the cap being configured to couple with the engagement to form a sealed space accommodating at least a portion of the sensor, wherein when the cap is coupled with the engagement, the tail of the sensor is located within the sealed space.

22. The application device according to claim 1, characterized in that, The housing includes a retaining portion, the moving body includes a locking portion releasably interlocked with the retaining portion, and the applying device includes a push triggering mechanism for triggering the housing to release the moving body. The push triggering mechanism includes a pressing portion and an actuating portion. By applying an action to the pressing portion, the actuating portion actuates the retaining portion or the locking portion to separate the two, thereby releasing the housing from holding the moving body.

23. The application device according to claim 22, characterized in that, The pressing part and the actuating part are integrally formed with the housing and are disposed at the far end of the housing.

24. An analyte monitoring system, comprising: The invention includes a monitoring device and an application device according to any one of claims 1-23, the monitoring device comprising an on-body unit and a sensor, the application device being used to apply the monitoring device to a host, wherein the sensor in the monitoring device applied to the host is at least partially located subcutaneously in the host to monitor the analyte.

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