Cosmetic composition for skin cell longevity

A cosmetic composition with a combination of active agents addresses the hallmarks of aging in skin cells by preventing proteostasis loss, micro-inflammatory processes, and mitochondrial dysfunction, enhancing skin cell longevity and health.

WO2026139327A1 Publication Date: 2026-07-02LOREAL SA
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Patent Information

Application Number
PCT/EP2025/087674
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-27
Filing Date
2025-12-17
Publication Date
2026-07-02

AI Technical Summary

Technical Problem

Existing cosmetic compositions fail to effectively address the multiple hallmarks of aging in skin cells, including loss of proteostasis, micro-inflammatory processes, cellular senescence, and mitochondrial dysfunction, which contribute to skin aging and deterioration.

Method used

A cosmetic composition comprising a combination of at least two active agents, including vitamin C, capryloylsalicylic acid, resveratrol, and other specific agents, that work synergistically to prevent or reduce these hallmarks, thereby maintaining skin cell longevity and health.

Benefits of technology

The composition effectively prevents or reduces the loss of proteostasis, micro-inflammatory processes, cellular senescence, and mitochondrial dysfunction, promoting skin cell longevity and overall skin health, particularly in individuals over 40 years old.

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Abstract

The present invention relates to a composition comprising a combination of at least two cosmetic active agents, said combination of active agents preventing or reducing the loss of proteostasis, preventing or reducing micro-inflammatory processes, preventing cellular senescence, and preventing or reducing mitochondrial dysfunction and / or stimulating mitochondrial energy metabolism in skin cells The invention also relates to the cosmetic use of such a composition for increasing the longevity of skin cells and skin tissues, for preventing or reducing the loss of proteostasis, preventing or reducing micro-inflammatory processes, preventing cellular senescence and preventing or reducing mitochondrial dysfunction and / or stimulating mitochondrial energy metabolism, in skin cells. Finally, the invention relates to a nontherapeutic cosmetic process for caring for keratin materials comprising the topical application of such a composition.
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