Engineered RNA-guided DNA-binding polypeptides

Abstract

The invention discloses engineered RNA-guided DNA-binding (RGDB) variants, especially of the Lachnospiraceae bacterium CRISPR-Casl2a (LbCasl2a) that exhibit superior performance, like enhanced specific binding to target DNA sequences, reduced non-specific DNA binding, or reduced catalytic activity. By introducing numerous substitution mutations across distinct structural blocks, the variants achieve stronger, more specific binding to target DNA while markedly reducing off-target or non-specific interactions. A second tier of mutations targets catalytic residues and other functional sites to generate catalytically inactive forms (dRGDP) that retain DNA-binding capability. These RGDB scaffolds can be fused to diverse effector domains, including transcriptional regulators, epigenetic modifiers, or nucleases, to modulate gene expression or repair defective genes in mammalian or plant cells. When coupled with base-editing enzymes such as adenosine or cytosine deaminases, the resulting adenine or cytosine base editors display enhanced editing efficiency and altered editing windows, enabling precise conversion of additional nucleobases.

Description

ENGINEERED RNA-GUIDED DNA-BINDING POLYPEPTIDESCROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority from U. S. Provisional Application 63 / 738,034, filed December 23, 2024, the content of which is incorporated herein by reference in its entirety.SEQUENCE LISTING

[0002] This application includes a sequence listing submitted electronically herewith. Said electronic file, created December 23, 2025, is named “ 125665. WO005. xml” and has a size of 1,216,173 bytes. The contents of said file are incorporated herein by reference in their entirety.BACKGROUND OF THE INVENTION

[0003] Clustered Regularly Interspaced Short Palindromic Repeats, abbreviated as CRISPR, are DNA sequences found in the genome of prokaryotes such as bacteria and archaea. These sequences are derived from pathogens (e.g., bacteriophages) that have previously infected the prokaryotes. CRISPR-associated (Cas) proteins, guided by CRISPR RNA (crRNA), bind to and degrade foreign genetic elements in a sequence-specific manner upon subsequent infection by the same or similar pathogens. To maintain the integrity of the CRISPR array, the cleavage of a DNA-target is tied to the recognition of a protospacer adjacent motif (PAM), usually three or four nucleotides in length, upstream of the target site.

[0004] Due to their ability to target specific nucleotide sequences, CRISPR-Cas systems have been modified and used as gene editing tools in eukaryotic cells such as mammalian cells and plant cells. However, DNA manipulation using native Cas proteins is risky given the potential for undesired double-stranded DNA breaks and the resultant genomic indels and cellular toxicity. Furthermore, much work remains to be done to improve gene editing efficiency of Cas proteins. In short, there is a need for Cas variants that have improved genomic editing efficiency and safety.SUMMARY OF THE INVENTION

[0005] The present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises 15 or more, 30 or more, 40 or more, optionally all, of substitution mutations selected from N33A, V38K, G49E, S60A, N63E, D64K, N75Q, N76K, K84D, T85K, N96K, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, F173Y, C175I, Y183F, S185D, M187I, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, S388E, Q399E, D439S, S465E, K478T, S551Q, N575S, and S1157K, relative to SEQ ID NO:1.

[0006] In one aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises mutations at three or more positions selected from S388, Q399, D439, S465, K478, S551, and N575, relative to SEQ ID NO: 1.

[0007] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide comprises any one of SEQ ID NOs:16, 18, 20, 22, 24, 26, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 232, 234, 236, 241, 243, 245, 247, 257, 258, 261, and 262.

[0008] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide comprises any one of SEQ ID NOs:135, 219, 220, 221, 228, 229, 230, 250, 252, 259, 260, and 263-293.

[0009] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises:i) substitution mutations at R935 and Q944, optionally wherein the substitution mutations are R935G and Q944K;ii) substitution mutations at F931, R935, and Q944, optionally wherein the substitution mutations are F931L, R935G, and Q944K;iii) substitution mutations at R935, K940, and Q944, optionally wherein the substitution mutations are R935G, K940G, and Q944K; oriv) substitution mutations at R833, E835, Q941, and Y943, optionally wherein the substitution mutations are R833M, E835D, Q941K, and Y943T.

[0010] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide having a catalytically active DNA nuclease (aRGDP), wherein the polypeptide is a variant of SEQ ID NO:1 and comprises substitution mutations S1030K and / or S1053P.

[0011] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide comprising substitution mutation D832K or D832L.

[0012] In another aspect, the present disclosure provides an RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises 15 or more, 30 or more, 40 or more, optionally all, of substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, N100K, G111S, N112H, SI 17K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D458E, S465E, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, S1007T, S1020T, S1024A, N1070S, V1083Q, F1084W, C1090D, Y1095F, N1100E, LI 114E, Al 122E, SI 125K, Al 129S, T1142E, SI 157K, El 168K, and II 174E, relative to SEQ ID NO:1.

[0013] Also provided in the present disclosure are fusion proteins comprising the aforementioned polypeptides, nucleic acids encoding the same, related expression vectors and cells, and use of these in methods of editing or regulating a target gene in a cell.

[0014] In another aspect, the present disclosure provides a fusion protein comprising:(a) a RNA-guided DNA-binding polypeptide having a catalytically inactive DNA nuclease (dRGDP), whereinthe polypeptide is a variant of SEQ ID NO: 1 and does not comprise substitution mutations at any one of positions D832, E925, D947, and DI 180, or a combination thereof; andeither (i) does not comprise substitution mutations at positions S1030 and S1053, or (ii) comprises substitution mutations S1030K and S1053P; and (b) a nucleotide deaminase domain.

[0015] Other features, objectives, and advantages of the invention are apparent in the detailed description that follows. It should be understood, however, that the detailed description, while indicating embodiments and aspects of the invention, is given by way of illustration only, not limitation. Various changes and modification within the scope of the invention will become apparent to those skilled in the art from the detailed description.BRIEF DESCRIPTION OF THE FIGURES

[0016] FIG. 1 is a schematic diagram showing the functional domains of an exemplary RNA-guided DNA-binding polypeptide (“RGDB” polypeptide) (a Cas polypeptide) and the four primary sequence blocks on which block variants were made.

[0017] FIG. 2 is a schematic diagram showing a configuration of a base editor. BPNLS: bipartite nuclear localization signal. dCas: catalytically dead Cas.

[0018] FIG. 3 is a schematic diagram showing a base editor linked to an enhanced green fluorescent protein (EGFP) via a self-cleaving T2A peptide coding sequence, wherein the base editor comprises a RGDB variant (a Cas variant) fused to an A-to-G deaminase via an XTEN linker. pCMV: CMV promoter. NLS: nuclear localization signal.

[0019] FIG. 4 is a bar graph showing indel and A-to-G base editing activities (normalized to MS0) of various RGDB variants (AA32, AA45, AA48, AA49, EF1s9, EF1s12, EF1s19, and AC 10) fused to an adenosine deaminase.

[0020] FIG. 5 is a bar graph showing indel and A-to-G base editing activities (normalized to MS0) of various RGDB variants (FM1-FM35) fused to an adenosine deaminase.

[0021] FIG. 6A is a schematic diagram of a RGDB variant linked to EGFP via a selfcleaving T2A peptide coding sequence. pCMV: CMV promoter. NLS: nuclear localization signal.

[0022] FIG. 6B is a bar graph showing indel activities (normalized to MS0) of various RGDB variants (FM11, FM12, FM13, FM14, FM17, and FM28) at two different target sites.

[0023] FIG. 7 is a bar graph showing indel activities (normalized to MS0) of various RGDB variants (DL186, DL187, DL188, DL189, DL190, and DL191) at two different target sites.

[0024] FIGs. 8A-B are bar graphs showing indel and A-to-G base editing activities (normalized to MS0) of various RGDB variants (FM11, FM12, FM13, FM14, FM17, FM28, DL165, DL186, DL187, DL188, DL189, DL190, and DL191) fused to an adenosine deaminase, at two different target sites.

[0025] FIG. 9 is a bar graph showing base editing activity and bystander activity of select DL variants fused to an adenosine deaminase relative to a positive control.

[0026] FIG. 10 is a heatmap showing three cycles of bacterial selection to identify the best substitution at position D832 to sustain base editing.DETAILED DESCRIPTION OF THE INVENTION

[0027] The present disclosure provides RGDB variants with improved properties, such as enhanced specific binding to target DNA sequences, reduced non-specific DNA binding, and / or reduced or no catalytic (endonuclease) activity. These RGDB variants may be fused to one or more effector domains to generate fusion proteins that can regulate expression of a target gene or repair a defective gene in eukaryotic cells such as mammalian cells (e.g., human cells) and plant cells.

[0028] In some embodiments, the RGDB variants are fused to a base editor domain (e.g., an adenosine deaminase or a cytosine deaminase) to generate a base editor, such as an adenine base editor (ABE) or a cytosine base editor (CBE). These base editors have improved editing efficiency and / or modified editing windows (i.e., editing additional and / or different nucleobases in the target sequence as compared to the parental base editor).I. RGDB Variants

[0029] Provided herein are engineered RGDB variants that have altered activity relative to a wildtype RGDB. A “RGDB variant” refers to a non-naturally occurring RGDB protein that contains one or more mutations (e.g., substitutions, deletions, and / or insertions) relative to a parental (e.g., wildtype) RGDB. In some embodiments, the RGDB variant herein contains one or more substitutions relative to a parental RGDB. The substitution may be made with an amino acid that has a different physiochemical characteristic (e.g., charge, polarity, size, and / or chemical class as defined by the amino acid side chain) as the wildtype residue.

[0030] For any given amino acid position, a substitution exemplified herein is not limiting. A different substitution may be made at that position by using an amino acid that has similar physiochemical properties to the exemplified substituting amino acid. For example, lysine has an equivalent charge to arginine, and an equivalent hydrophilicity to aspartic acid, glutamic acid, and arginine; and a similar accessible surface to arginine, similar accessible surface area to arginine, tryptophan, and tyrosine. Thus, using the E95K substitution as an example, E95R is an examples of an amino acid substitution having an equivalent charge; E95D and E95R are examples of amino acid substitutions having an equivalent hydrophilicity; and E95R, E95W, and E95 Y are examples of amino acid substitutions having a similar accessible surface area. In this example, E95R is equivalent to E95K in all of the aforementioned three types of characteristics (i.e., charge, hydrophilicity, and accessible surface area).

[0031] In some embodiments, the RGDB variant herein comprises an amino acid sequence that is at least 75% (e.g., at least 80, 85, 90, or 95%) identical to its parental RGDB sequence. In some embodiments, the RGDB variant herein comprises an amino acid sequence that is no more than 90% identical to its parental RGDB sequence. In some embodiments, the RGDB variant comprises an amino acid sequence that is between 75% and 90% (e.g., 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, or 90%) identical to its parental RGDB sequence. The percent identity of two amino acid sequences (or of two nucleic acid sequences) may be obtained by, e.g., BLAST® using default parameters (available at the U. S. National Library of Medicine’s National Center for Biotechnology Information website); in some embodiments, the length of a reference sequence aligned for comparison purposes is at least 50% (e.g., at least 60, 70, 80, or 90% of the reference sequence.

[0032] In some embodiments, the RGDB variant comprises one or more mutations (e.g., substitutions) relative to a wildtype RGDB protein (SEQ ID NO: 1). While exemplary RGDB variants derived from SEQ ID NO:1 are described below, the present disclosure encompasses RGDB variants that are derived from other parental RGDB sequences and contain the same or equivalent mutations at positions corresponding to those illustrated for SEQ ID NO:1. “Corresponding” amino acid positions can be readily identified by aligning any RGDB amino acid sequence to SEQ ID NO: 1.A. Series I Variants

[0033] In some embodiments, the RGDB variant herein is a variant of SEQ ID NO: 1 and comprises mutations at 15 or more, 20 or more, 25 or more, 30 or more, 35 or more, or 40 or more positions selected from N33, V38, G49, S60, N63, D64, N75, N76, K84, T85, N96, N100, G111, N112, S117, T126, E130, D136, A139, N142, N145, F173, C175I, Y183, S185, M187, D194, A195, E221, S248, T266, V280, G293, E298, E302, S388, Q399, D439, S465, K478, S551, N575, and SI 157 of SEQ IDNO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from N33A, V38K, G49E, S60A, N63E, D64K, N75Q, N76K, K84D, T85K, N96K, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, F173Y, C175I, Y183F, S185D, M187I, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, S388E, Q399E, D439S, S465E, K478T, S551Q, N575S, and SI 157K. In some embodiments, the RGDB variant comprises all of these substitutions.

[0034] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from H67, 199, A334, G393, E398, D450, N468, E476, T967, S1030, S1053, S1093, QI 108, Al 113, SI 119, DI 158, and G1196 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from H67S / N, I99E / D, A334S / N, G393E / K, E398S / A, D450S / E, N468H / R, E476K / S, T967S / P, S1030T / K, S1053Q / P, S1093D / K, Q1108N / D, A1113K / D, S1119N / D, D1158E / N, and G1196R / D. In some embodiments, the one or more substitutions are selected from H67S, I99E, A334S, G393E, E398S, D450S, N468H, E476K, T967S, S1030T, S1053Q, S1093D, Q1108N, Al 113K, SI 119N, DI 158E, and G1196R. In some embodiments, the RGDB variant comprises all of these substitutions. In other embodiments, the one or more substitutions are selected from H67N, I99D, A334N, G393K, E398A, D450E, N468R, E476S, T967P, S1030K, S1053P, S1093K, Q1108D, A1113D, SI 119D, DI 158N, and G1196D. In some of these other embodiments, the RGDB variant comprises all of these substitutions.

[0035] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from T346, D350, D360, A364, E365, D383, D384, D405, E412, Q420, E433, K434, A438, K448, D458, N481, S485, D519, D537, and G550 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from T346S, D350T, D360E, A364N, E365K, D383E, D384K, D405S, E412Q, Q420D, E433K, K434S, A438R, K448Q, D458E, N481E, S485A, D519T, D537N, and G550D. In some embodiments, the RGDB variant comprises all of these substitutions.

[0036] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from L59, S79, E98, A166, and D188 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from L59R, S79D, E98Q, A166E, and D188K. In some embodiments, the RGDB variant comprises all of these substitutions.

[0037] In some embodiments, the RGDB variant further comprises a mutation, optionally a substitution, at F1084 of SEQ ID NO: 1. In some embodiments, the substitution is F1084W.

[0038] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from K1015, T1019, D1023, E1040, R1054, A1094, E1097, KI 101, QI 107, KI 200, A 1201, and DI 203 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutationsare substitutions, optionally selected from K1015Y, T1019E, D1023R, E1040R, R1054T, A1094K, E1097S, KI 101 A, QI 107E, K1200Q, A1201N, and D1203E. In some embodiments, the RGDB variant comprises all of these substitutions.

[0039] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from C965, K1064, and El 117 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from C965NZE, K1064V / I, and E1117K / S. In some embodiments, the one or more substitutions are selected from C965N, K1064V, and El 117K. In some embodiments, the RGDB variant comprises all of these substitutions. In other embodiments, the one or more substitutions are selected from C965E, KI 0641, and El 117S. In some of these other embodiments, the RGDB variant comprises all of these substitutions.

[0040] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from S962, N963, S1007, S1020, S1024, N1070, V1083, C1090, Y1095, N1100, LI 114, Al 122, SI 125, Al 129, T1142, El 168, and 11174 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from S962K, N963D, S1007T, S1020T, S1024A, N1070S, V1083Q, C1090D, Y1095F, N1100E, LI 114E, A1122E, S1125K, A1129S, T1142E, E1168K, and I1174E. In some embodiments, the RGDB variant comprises all of these substitutions.

[0041] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from K972, L1000, and 11074 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from K972H, L1000N, and I1074K. In some embodiments, the RGDB variant comprises all of these substitutions.

[0042] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from R35, E95, D156, E159, D213, G291, Y294, N306, D423, S431, A451, T480, D489, G532, G576, A604, M957, A966, 1996, and A1022 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from R35N / Q, E95K / R, D156E / N, E159K / N, D213K / R, G291P, Y294F, N306E / D, D423Q / N, S431T / N, A451E / D, T480D / V / S, D489E / Q, G532N, G576N / S, A604Q / S, M957L / I, A966E / D, I996V / L, and A1022E / Q. In some embodiments, the one or more substitutions are selected from R35N, E95K, D156E, E159K, D213K, G291P, Y294F, N306E, D423Q, S431T, A451E, T480D / V,D489E, G532N, G576N, A604Q, M957L, A966E, I996V, and A1022E. In some embodiments, the RGDB variant comprises all of these substitutions. In other embodiments, the one or more substitutions are selected from R35Q, E95R, D156N, E159N, D213R, N306D, D423N, S431N, A451D, T480S, D489Q, G576S, A604S, M957I, A966D, I996L, and A1022Q. In some of these other embodiments, the RGDB variant comprises all of these substitutions.

[0043] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from K1015, T1019, D1023, S1030, S1053, R1054, A1094, A1201, and D1203 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from K1015Y, T1019E, D1023R, S1030T / K, S1053Q / P, R1054T, A1094K, A1201N, and D1203E.

[0044] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, S1157K, D1158E, G1196R, K1200Q, A1201N, andD1203E.

[0045] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, S60A, N63E, D64K, H67N, N75Q, N76K, F81Y, K84D, T85K, E95K, N96K, I99D, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, F173Y, C175I, Y183F, S185D, Ml 871, D194K, A195K, E207K, D213K, E217D, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q,R1054T, S1093D, A1094K, E1097S, KI 101 A, QI 107E, QI 108N, Al 113K, SI 119N, S1157K, D1158E, G1196R, K1200Q, A1201N, and D1203E.

[0046] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, S332D, A334N, N356S, A375K, V376E, S388E, G393K, E398A, Q399E, E402K, A406R, K421L, D423Q, Y426E, G430S, S431T, D439S, D450E, A451E, A454K, V463I, S465E, N468R, Y469F, F474L, E476S, K478T, T480D, V491N, L492D, I496K, L498S, V500I, H502K, G532N, S551Q, Y562H, A563K, C565A, V574K, N575S, G576S, I581M, D611E, Q613L, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, SI 157K, DI 158E, G1196R, K1200Q, A1201N, andD1203E.

[0047] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

[0048] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H,V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965E, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, S1053P, K1064I, N1070S, I1074K, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, Q1108N, A1113D, L1114E, E1117S, S1119D, A1122E, Y1124F, S1125K, A1129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

[0049] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, A1046E, S1053P, A1057E, K1064V, N1070S, I1074K, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, QI 108D, Al 113D, LI 114E, El 117K, SI 119D, Al 122E, SI 125K, Al 129S, T 1142E, S 1157K, D 1158N, E 1168K, 11174E, and G1196D.

[0050] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, I996V, S1007T, S1020T, A1022E, S1024A, S1030K, M1035R, S1053P, A1057E, K1064V,N1070S, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

[0051] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, SI 024 A, SI 03 OK, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

[0052] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, R35Q, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95R, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156N, E159N, A166E, F173Y, Cl 751, Y183F, S185D, Ml 871, D188K, D194K, A195K, D213R, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, N306D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

[0053] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E,D405S, E412Q, Q420D, D423N, S431N, E433K, K434S, A438R, D439S, K448Q, D450S, A451D, D458E, S465E, N468H, E476K, K478T, T480S, N481E, S485A, D489Q, D519T, D537N, G550D, S551Q, N575S, G576S, A604S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

[0054] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

[0055] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, T967S, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, S 1157K, D 1158E, G1196R, K 1200Q, A1201N, and D 1203E.

[0056] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions N33A, V38K, G49E, S60A, N63E, D64K, H67N, N75Q, N76K, F81 Y, K84D, T85K, N96K, I99D, N100K, G111S, N112H, SI 17K, T126E, E130K, D136S, A139E, N142E, N145K, F173Y, C175I, Y183F, S185D, M187I, D194K, A195K, E207K,E217D, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, T967S, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S 1119N, S 1157K, D 1158E, G1196R, K 1200Q, A1201N, and D 1203E.

[0057] In some embodiments, the RGDB variant is catalytically inactive, optionally comprising the substitution D832A, D832L, or D832K relative to SEQ ID NO:1.

[0058] In some embodiments, the RGDB variant is catalytically inactive, optionally comprising mutations at one or more positions selected from R833, E835, R836, F931, R935, K940, Q941, Y943, and Q944, relative to SEQ ID NO:1. In some embodiments, the mutations are substitution mutations, optionally selected from R833M, E835D, R836G, F931L, R935G, K940G, Q941K, Y943T, and Q944K. In some embodiments, the RGDB variant comprises substitutions Q944K and R935G. In some embodiments, the RGDB variant comprises substitutions Q944K, F931L, and R935G. In some embodiments, the RGDB variant comprises substitutions K940G, Q944K, and R935G. In some embodiments, the RGDB variant comprises substitutions R836G, Q944K, and R935G. In some embodiments, the RGDB variant comprises substitutions R833M, E835D, Y943T, and R935G. In some embodiments, the RGDB variant comprises substitutions R833M, E835D, Y943T, and Q941K.B. Series II Variants

[0059] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises mutations at three or more positions in a block spanning positions 326-606 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at three or more positions selected from S388, Q399, D439, S465, K478, S551, andN575 of SEQ IDNO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from S388E, Q399E, D439S, S465E, K478T, S551Q, and N575S. In some embodiments, the RGDB variant comprises all of these substitutions.

[0060] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from A334, G393, E398, D450, N468, and E476 of SEQ ID NO:1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from A334N / S, G393KZE, E398A / S, D450E / S, N468R / H, and E476S / K. In some embodiments, the one ormore substitutions are selected from A334N, G393K, E398A, D450E, N468R, and E476S. In some embodiments, the RGDB variant comprises all of these substitutions. In other embodiments, the one or more substitutions are selected from A334S, G393E, E398S, D450S, N468H, and E476K. In some of these other embodiments, the RGDB variant comprises all of these substitutions.

[0061] In some embodiments, the RGDB variant further comprises mutations at one or more positions selected from D423, S431, A451, T480, D489, G576, and A604 of SEQ ID NO: 1. In some embodiments, the RGDB variant comprises mutations at all of these positions. In some embodiments, the mutations are substitutions, optionally selected from D423Q / N, S431T / N, A451E / D, T480D / V / S, D489E / Q, G576N / S, and A604Q / S. In some embodiments, the one or more substitutions are selected from D423Q, S431T, A451E, T480D / V, D489E, G576N, and A604Q. In some embodiments, the RGDB variant comprises all of these substitutions. In other embodiments, the one or more substitutions are selected from D423N, S431N, A451D, T480S, D489Q, G576S, and / or A604S. In some of these other embodiments, the RGDB variant comprises all of these substitutions.

[0062] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, and A604Q.

[0063] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitutions S332D, A334N, N356S, A375K, V376E, S388E, G393K, E398A, Q399E, E402K, A406R, K421L, D423Q, Y426E, G430S, S431T, D439S, D450E, A451E, A454K, V463I, S465E, N468R, Y469F, F474L, E476S, K478T, T480D, V491N, L492D, I496K, L498S, V500I, H502K, G532N, S551Q, Y562H, A563K, C565A, V574K, N575S, G576S, I581M, D611E, and Q613L.

[0064] In some embodiments, the RGDB variant is catalytically inactive, optionally comprising the substitution D832A, D832L, or D832K, relative to SEQ ID NO: 1.

[0065] In some embodiments, the RGDB variant is catalytically inactive, optionally comprising mutations at one or more positions selected from R833, E835, R836, F931, R935, K940, Q941, Y943, and Q944, relative to SEQ ID NO:1. In some embodiments, the mutations are substitution mutations, optionally selected from R833M, E835D, R836G, F931L, R935G, K940G, Q941K, Y943T, and Q944K. In some embodiments, the RGDBvariant comprises substitutions Q944K and R935G. In some embodiments, the RGDB variant comprises substitutions Q944K, F931L, and R935G. In some embodiments, the RGDB variant comprises substitutions K940G, Q944K, and R935G. In some embodiments, the RGDB variant comprises substitutions R836G, Q944K, and R935G. In some embodiments, the RGDB variant comprises substitutions R833M, E835D, Y943T, and R935G. In some embodiments, the RGDB variant comprises substitutions R833M, E835D, Y943T, and Q941K.C. Series III Variants

[0066] The present disclosure also provides catalytically inactive RGDB variants. In some embodiments, the RGDB variant is a catalytically inactive variant of SEQ ID NO:1 and comprises mutations at positions R935 and Q944 of SEQ ID NO: 1. In some embodiments, the mutations are substitutions, optionally R935G and Q944K.

[0067] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises mutations at positions F931, R935, and Q944 of SEQ ID NO: 1. In some embodiments, the mutations are substitutions, optionally F931L, R935G, and Q944K.

[0068] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises mutations at positions R935, K940, and Q944 of SEQ ID NO: 1. In some embodiments, the mutations are substitutions, optionally R935G, K940G, and Q944K.

[0069] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises mutations at positions R833, E835, Q941, and Y943. In some embodiments, the mutations are substitutions, optionally R833M, E835D, Q941K, and Y943T.

[0070] In some embodiments, the RGDB variant is a variant of any one of SEQ ID NOs:16, 18, 20, 22, 24, 26, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 232, 234, 236, 241, 243, 245, and 247, and said variant further comprises a combination of mutations, which combination is selected from the group consisting of (A) R935 and Q944; (B) F931, R935, and Q944; (C) R935, K940, and Q944; (D) R833, E835, Q941, and Y943; (E) R836, Q944, and R935; and (F) R833, E835, Y843, and R935; wherein (A) is optionally R935G and Q944K; (B) is optionally F931L, R935G, and Q944K; (C) is optionally R935G, K940G, and Q944; (D) is optionally R833M, E835D, Q941K, and Y943T; (E) is optionally R836G, Q944K and R935G; and (F) is optionally R833M, E835D, Y943T, and Q941K.

[0071] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises substitution mutation D832K or D832L.D. Series IV Variants

[0072] In some embodiments, the RGDB variant is a variant of SEQ ID NO: 1 and comprises mutations at positions S1030 and / or S1053. In some embodiments, the mutations are substitutions, optionally S1030K and / or S1053P. In some embodiments, the RGDB variant has a catalytically active DNA nuclease (aRGDP). In other embodiments, the RGDB variant has a catalytically inactive DNA nuclease (dRGDP), wherein the dRGDP variant does not comprise substitution mutations at any one of positions D832, E925,D947, and DI 180, or a combination thereof. In some embodiments, the dRGDP variant further comprises substitution mutations R836G, Q944K, and R935G. In other embodiments, the dRGDP variant further comprises substitution mutations R833M, E835D, Y943T, and Q941K.E. Biological Properties of RGDB Variants

[0073] The RGDB variants herein have biological properties suitable for different gene editing goals.1. DNA Cleavage

[0074] In some embodiments, the present RGDB variant retains the endonuclease activity of the parental RGDB protein. For example, the RGDB variant may cleave double-stranded DNA (dsDNA), single-stranded DNA (ssDNA), and / or RNA. In some embodiments, the RGDB variant is a nickase (also referred to as nRGDB), which cleaves only one strand of a dsDNA. In some embodiments, the nRGDB cleaves only the target strand of a dsDNA; in other embodiments, the nRGDB cleaves only the non-target strand of a dsDNA.

[0075] In some embodiments, the present RGDB variant is catalytically inactive (also referred to as dead RGDB or dRGDB). A dRGDB complexes with a crRNA and binds to a DNA sequence specified by that crRNA’ s targeting domain; however, it does not cleave either strand of the target DNA. In some embodiments, a dRGDB comprises an alanine or glycine substitution at one or more residues corresponding to D832, E925, and / or DI 180 of SEQ ID NO: 1.

[0076] DNA cleavage activity of a RGDB protein can be assessed by any method known in the art. Activity of a parental RGDB protein or a variant thereof can be assessed in vitro by incubating the RGDB protein with fluorescent labeled DNA containing the target sequence and analyzing the DNA on a gel (Stella et al., Nature (2017) 546(7659):559-63). Activity of a parental RGDB protein or a variant thereof in the cell can be assessed bytransfecting the cells with a plasmid encoding the RGDB protein or its variant and analyzing the small insertion or deletion (indel) in the genomic DNA using NGS or any other suitable method (Bennett et al., Nucleic Acids Res. (2020) 48(21):11958-81). For transcription regulation and base editing, it may be desirable to use a RGDB variant that is catalytically inactive (dRGDB) or has only nickase activity (nRGDB).2. DNA-Binding Affinity

[0077] In some embodiments, the present RGDB variant has a higher binding affinity for a target DNA as compared to its parent. The binding affinity of a parental RGDB protein or a variant thereof for a target DNA may be assessed using any method known in the art. For example, DNA binding affinity may be assessed by flow-induced dispersion analysis (FID A) (Jensen H. & Ostergaard J., J Am Chem Soc. (2010) 132(12):4070-l). In FID A, one measures the dispersion of fluorescently tagged molecules in a capillary when flow is applied. Larger ensembles (covalent or non-covalent) are dispersed more and the Taylorgram is broadened. For higher affinity non-covalent interactions, the dispersion is higher and the Taylorgram is broadened.

[0078] For base editing or epigenetic editing, it may be desirable to use a RGDB variant that has increased DNA-binding affinity in order to improve editing efficiency. In some embodiments, the RGDB variant is catalytically dead. Examples of RGDB variants having increased DNA-binding affinity, include, but are not limited to DL106, DL107, DL160, DL165, DL168, DL169, and DL173, as well as their catalytically dead counterparts (e.g., DL106a, DL107a, DL160a, DL165a, DL168a, DL169a, and DL173a).3. PAM Specificity

[0079] In some embodiments, the RGDB variant herein has altered PAM specificity as compared to its wildtype parent. The PAM specificity of a WT RGDB or a variant thereof may be assessed using any method known in the art.F. Sequences of Exemplary RGDB Variants

[0080] Non-limiting, exemplary RGDB variant sequences, as well as the parental RGDB sequence, are shown in Table 1 below. The variants listed in Table 1 may further comprise a methionine (Met, M) residue at the N-term and / or a histidine (His, H) residue at the C-term.Table 1. Exemplary RGDB SequencesName Sequence SEQ Parental MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFI 1 RGDB NDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDII ETILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESName Sequence SEQ GEKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNK NSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLK KKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEK LFDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDI LLKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIM DKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGT FKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSF ESASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAEL FMRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCP KNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRI KTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSG FKNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGF IFYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSR TDADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLC EQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKN ADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKH MSO MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFI 2NDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDII ETILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISN MDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTES GEKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNK NSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLK KKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEK LFDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDI LLKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIM DKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGT FKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSF ESASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAEL FMRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCP KNIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRI KTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSG FKNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGF IFYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSR TDADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLC EQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKN ADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKH FM84 MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFI 3NDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDII ETILPEFLDDKDEIALVNSFNGFTTAFTGFFRNRENMFSEEAKSTSIAFRCINENLTRYISN MDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIRVYNAIIGGFVTES GEKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGRGYTSDEEVLEVFRNTLNK NSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKRIFGEWNVIRDKWNAEYDDIHLK KKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEK LFDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDI LLKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIM DKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGT FKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSF ESASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAEL FMRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCP KNIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRI KTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSG FKNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFName Sequence SEQ IFYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSR TDADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLC EQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKN ADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKH DL10 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEEKRLLVEDEKRAEDYKEVKKLLDEYYLAFIN 4KVLSSIKLNNLEKYISLFRKSKKTEKENKELKNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPDFLEDKSEIELVNSFDGFTTAFTGFFDNRENMFSDEEKSTSIAFRCINENLTRYIDNM KIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DLlOa SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEEKRLLVEDEKRAEDYKEVKKLLDEYYLAFIN 5KVLSSIKLNNLEKYISLFRKSKKTEKENKELKNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPDFLEDKSEIELVNSFDGFTTAFTGFFDNRENMFSDEEKSTSIAFRCINENLTRYIDNM KIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL18 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 6EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL18a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 7EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL19 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEKKRLLVEDEKRAEDYKKVKKLLDDYYLAFIN 8KVLESIKLDNLYEYISLFRKNNKTEKENKELDNLEINLRKEIAKAFKGNEKYKSLFKKDIIE TILPDFLEDKSEIQLVNSFDGFTTAFTGFFDNRENMFSDEDKSTSIAFRCINENLTRYINNM QIFEKVIKIFDKHEVQEIKKKILNSGYDVSDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL19a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEKKRLLVEDEKRAEDYKKVKKLLDDYYLAFIN 9KVLESIKLDNLYEYISLFRKNNKTEKENKELDNLEINLRKEIAKAFKGNEKYKSLFKKDIIE TILPDFLEDKSEIQLVNSFDGFTTAFTGFFDNRENMFSDEDKSTSIAFRCINENLTRYINNM QIFEKVIKIFDKHEVQEIKKKILNSGYDVSDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL20 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEEKRLLVEDEKRAEDYKKVKKLLDEYYLDFIN 10KVLSSIKLANLEDYISLFRKSNSTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKEEIQLVNSFDGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYIDNM KIFEKVKQIFDKHEVQEIKKKILNSGYDVSDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL20a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEEKRLLVEDEKRAEDYKKVKKLLDEYYLDFIN 11KVLSSIKLANLEDYISLFRKSNSTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKEEIQLVNSFDGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYIDNM KIFEKVKQIFDKHEVQEIKKKILNSGYDVSDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL21 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIHKKRLLVEDEKRAEDYKEVKKLLDEYYLDFIN 12EVLESIKLNNLQEYISLFRKDNKTEKENKELKNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPDFLYDKSEIQLVNSFEGFTTAFTGFFDNRENMFSSEDKSTSIAFRCINENLTRYIRNM QIFEKVIEIFDKHEVQEIKKKILNSKYDVDDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL21a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIHKKRLLVEDEKRAEDYKEVKKLLDEYYLDFIN 13EVLESIKLNNLQEYISLFRKDNKTEKENKELKNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPDFLYDKSEIQLVNSFEGFTTAFTGFFDNRENMFSSEDKSTSIAFRCINENLTRYIRNM QIFEKVIEIFDKHEVQEIKKKILNSKYDVDDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEEYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL22 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEKKRLLVEDEKRAEDYKKVKKLLDEYYLAFIN 14KVLNSIKLTNLKEYISLFRKNKKTEKENKELKNLEINLRKEIAKAFKGNENYKSLFKKDIIE TILPKFLYDKSEIELVNSFEGFTTAFTGFFDNRENMFSSEDKSTSIAFRCINENLTRYIDNMKIFEKVIQIFDKHEVQEIKNKILNSGYDVDDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESGName Sequence SEQ EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEKYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL22a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEKKRLLVEDEKRAEDYKKVKKLLDEYYLAFIN 15KVLNSIKLTNLKEYISLFRKNKKTEKENKELKNLEINLRKEIAKAFKGNENYKSLFKKDIIE TILPKFLYDKSEIELVNSFEGFTTAFTGFFDNRENMFSSEDKSTSIAFRCINENLTRYIDNM KIFEKVIQIFDKHEVQEIKNKILNSGYDVDDFFEGDFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYSEKYTSDSEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL23 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 16DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL23a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 17DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL24 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 18DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISNISKKIFGEWNVIRRKWNEYYDDIHLKK KAVVTEKYEYERRKDFKKIESFSLASLQEYAEADLSVVDKLKEIIINKVEEIYKVYGESKEL FDTSFVLEKSLKENKEVVAIMKELLDSVKNFERYIKAFFGSGDELERDERFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVEDNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL24a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 19DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISNISKKIFGEWNVIRRKWNEYYDDIHLKK KAVVTEKYEYERRKDFKKIESFSLASLQEYAEADLSVVDKLKEIIINKVEEIYKVYGESKEL FDTSFVLEKSLKENKEVVAIMKELLDSVKNFERYIKAFFGSGDELERDERFYGKFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVEDNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL25 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 20DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL25a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 21DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL26 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 22DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL26a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 23DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL27 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 24DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISNISKKIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEQRRRKEFKKIKSFSLASLQEYASADLSVVDKLKEIIINKVEEIYKVYGESKSL FDTEFVLEKSLKQNETVVAIMKNLLDSVKEFEHYIKAFFGSGDEDDRDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMDGWDKNKETDYRATILRYDEKYYLAIMD KKYAKCLQKIDKDDVSDNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL27a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 25DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISNISKKIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEQRRRKEFKKIKSFSLASLQEYASADLSVVDKLKEIIINKVEEIYKVYGESKSL FDTEFVLEKSLKQNETVVAIMKNLLDSVKEFEHYIKAFFGSGDEDDRDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMDGWDKNKETDYRATILRYDEKYYLAIMD KKYAKCLQKIDKDDVSDNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL28 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 26DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL28a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 27DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGName Sequence SEQ EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL29 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 28DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKESINKYPKWSHAYNFKFSETSDYNDIADFYREVEEQGYKLSFR DASKDDVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDERNNGQIRLSGGAELF MRYASLKKKELVVHPANSPIKNKNPDNPKKTTTLKYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKEKDEPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL29a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 29DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKESINKYPKWSHAYNFKFSETSDYNDIADFYREVEEQGYKLSFR DASKDDVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDERNNGQIRLSGGAELF MRYASLKKKELVVHPANSPIKNKNPDNPKKTTTLKYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKEKDEPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL30 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 30DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASINDYPKWSHAYNFKFSETSTYEDIADFYREVEEQGYKISFT NASKEDVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEENLGQIRLSGGAELF MRYASLKKDELVVHPANSPIVNKNPDNPKKTTTLTYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKQKDEPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL30a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 31DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASINDYPKWSHAYNFKFSETSTYEDIADFYREVEEQGYKISFT NASKEDVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEENLGQIRLSGGAELF MRYASLKKDELVVHPANSPIVNKNPDNPKKTTTLTYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKQKDEPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL31 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 32DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKASIEKYPKWSKAYGFKFSETSSYEDIADFYREVEEQGYKLSFT DASKDYVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDEENNGQIRLSGGAELF MRKASLKKDELVVHPANSPIKNKNPDNPKKTTTLKYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKSNDEPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL31a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 33DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKASIEKYPKWSKAYGFKFSETSSYEDIADFYREVEEQGYKLSFT DASKDYVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDEENNGQIRLSGGAELF MRKASLKKDELVVHPANSPIKNKNPDNPKKTTTLKYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKSNDEPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL32 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 34DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKESIEDYPKWSHAYGFKFSETKEYQDIADFYREVEEQGYKLSFV YASKDYVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDEENLGQIRLSGGAELF MRKASLKKDELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKSEDDPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL32a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 35DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHALIDFFKESIEDYPKWSHAYGFKFSETKEYQDIADFYREVEEQGYKLSFV YASKDYVDKLVEEGKLYMFQIYNKDFSDKSTGTPNLHTMYFKLLFDEENLGQIRLSGGAELF MRKASLKKDELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKSEDDPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL33 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 36DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASIEKYPKWSKAYNFKFSETSSYQDIAEFYREVEEQGYKLSFV KASKSDVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEDNLGQIRLSGGAELF MRKASLKKDELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKQEDDPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL33a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 37DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASIEKYPKWSKAYNFKFSETSSYQDIAEFYREVEEQGYKLSFV KASKSDVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEDNLGQIRLSGGAELFName Sequence SEQ MRKASLKKDELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKQEDDPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL34 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 38DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASINKYPKWSKAYGFSFSETKDYQDIADFYREVEEQGYKISFR DASKDYVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEDNNGQIRLSGGAELF MRKASLKKKELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKNNDEPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL34a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 39DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHDLIDFFKASINKYPKWSKAYGFSFSETKDYQDIADFYREVEEQGYKISFR DASKDYVDKLVEEGKLYMFQIYNKDFSDKSKGTPNLHTMYFKLLFDEDNNGQIRLSGGAELF MRKASLKKKELVVHPANSPIENKNPDNPKKTTTLEYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKNNDEPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCE QSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL35 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 40DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGName Sequence SEQ EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL35a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 41DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL36 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 42DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCAPGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLYTKYESIEQSKKFISTFDRIMYVPEKDLFEFALDYKNFTDT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTDEYKSLFNRYGINYKDGDIRELLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNDEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKETENEKLDKVKIAISNKEWLEYAQTSVK DL36a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 43DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCAPGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIEQSKKFISTFDRIMYVPEKDLFEFALDYKNFTDT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTDEYKSLFNRYGINYKDGDIRELLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNDEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKETENEKLDKVKIAISNKEWLEYAQTSVK DL37 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 44DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYESIDRSKKFISTFDRIMYVPEKDLFEFALDYKNFQDT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEKYKSLFNAYGINYEDGDIRMLLCE QDDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKNGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAINQFKENEEEKLDKVKIAISNKEWLEYAQTSVK DL37a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 45DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYESIDRSKKFISTFDRIMYVPEKDLFEFALDYKNFQDT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEKYKSLFNAYGINYEDGDIRMLLCE QDDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKNGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAINQFKENEEEKLDKVKIAISNKEWLEYAQTSVK DL38 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 46DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIDESKKFISTFDRIMYVPERDLFEFALDYKNFTDT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTEKYKKLFNQYGINYEDGDIRELLCE QEDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKNGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKQNENEKLDKVKIAISNKEWLEYAQTSVK DL38a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 47DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIDESKKFISTFDRIMYVPERDLFEFALDYKNFTDT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTEKYKKLFNQYGINYEDGDIRELLCE QEDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKNGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKQNENEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL39 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 48DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL39a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 49DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL40 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 50DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCAPGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIDQSKKFISKFDRIMYVPEKDLFEFALDYKNFNTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTEEYKSLFNAYGINYKNGDIRKLLCE QEDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNEEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAINQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL40a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 51DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDKWNAEYDDIHLKK KAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVEKLKEIIIQKVDEIYKVYGSSEKL FDADFVLEKSLKKNDAVVAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMD KKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCAPGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIDQSKKFISKFDRIMYVPEKDLFEFALDYKNFNTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTEEYKSLFNAYGINYKNGDIRKLLCE QEDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNEEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAINQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL53 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 52DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL53a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 53DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGName Sequence SEQ EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL54 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 54DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL54a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 55DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL55 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 56DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL55a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 57DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL56 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 58DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL56a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 59DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL57 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 60DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL57a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 61DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSDGIFVKNGPAISNISKKIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEYERRKEFKKIKSFSLSDLQEYASADLSVVQKLKEIIIDKVSEIYKVYGESDDL FDRSFVLEKSLKQNEEVVAIMKELLDSVKEFERYIKAFFGKGTEVERDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKNKETDYRATILRYNQKYYLAIMD KKYAKCLQKIDKDDVESNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL58 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 62DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL58a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 63DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSEGIFVKNGPAISSISKTIFGEWNVIREKWNNYYDDIHLKK KAVVTEKYEERRRKEFKKIKSFSLSSLQEYAEADLSVVQKLKEIIIEKVAEIYKVYGESDSL FDRSFVLEKSLKENETVVAIMKELLDSVKEFERYIKAFFGKGEELDRDEAFYGKFVLAYDIL LKVDHIYDAIRNYVTQKPYSKKKFKLYFQNPQFMSGWDKSKETDYRATILRYNNKYYLAIMD KKYAKCLQKIDKDDVGNNYEKINYKLLPGPNKMLPKVFFSKKWMKYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL59 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 64DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL59a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 65DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL60 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 66DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGName Sequence SEQ EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL60a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGVKKLLDRYYLSFIN 67DVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEINLRKEIAKAFKGNEGYKSLFKKDIIE TILPEFLDDKDEIALVNSFNGFTTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNM DIFEKVDAIFDKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL71 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 68EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL71a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 69EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL72 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 70EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL72a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 71EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLNTKYSSIEQSKKFISTFDRIMYVPERDLFEFALDYKNFNKT DADYIKKWKLYSYGNRIRIFRNPKKNNVWDWEEVCLTEEYKKLFNQYGINYENGDIRKLLCE QTDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNAKGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIEQFKETEEEKLDKVKIAISNKEWLEYAQTSVK DL75 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 72EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL75a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 73EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL76 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 74EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL76a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIKAKRLLVEDEKRAEDYKEVKKLLDKYYLAFIN 75EVLNSIKLNNLQKYISLFRKDKKTEKENKELDNLEINLRKEIAKAFKGNEEYKSLFKKDIIE TILPKFLRDKSEIELVNSFKGFTTAFTGFFDNRENMFSKEEKSTSIAFRCINENLTRYINNM QIFEKVIEIFDKHEVQEIKKKILNSNYDVSDFFEGNFFNFVLTQEGIDVYNAIIGGFVTESG EKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYPEKYTSDKEVLEVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL86 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 76KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL86a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 77KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL87 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 78KVLSSIKLKNLQKYISLFRKSKRTEKENKELKDLQDKLRKEIAKAFKSHEGYKKLFKKDIIE KILPKFLDDKSEIELVESFKGFTTAFTGFFQNRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL87a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 79KVLSSIKLKNLQKYISLFRKSKRTEKENKELKDLQDKLRKEIAKAFKSHEGYKKLFKKDIIE KILPKFLDDKSEIELVESFKGFTTAFTGFFQNRKNMFSEEAKSTSIAYRIINENLTRFIDNIDIFEKVKKIFDKHEVQEIKKKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL88 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 80KVLSSIKLKNLQKYISLFRKSKRTEKENKELKKLQDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKDEIALVESFKGFTTAFTGFFKNRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKKEVQEIKEKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL88a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIEAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 81KVLSSIKLKNLQKYISLFRKSKRTEKENKELKKLQDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKDEIALVESFKGFTTAFTGFFKNRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKKEVQEIKEKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL89 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 82KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL89a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 83KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSNGIFVKNGPAISNISKTIFGEWNVIRRKWNNYYDDIHLKK KAVVTEKYEQRRRKDFKKIKSFSLAELQEYAEADLSVVQKLKEIIIEKVAEIYKVYGTSKDL FDRSFVLEKSLKQNSEVVAIMKNLLDSVKDFERYIKAFFGSGTEDDRDENFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMSGWDKNKETDYRATILRYDNKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL106 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 84KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL106a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 85KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL107 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 86KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL107a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 87KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL150 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 88KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDEIHLKK KKEVTEKYEDDRRKDFKKIKSFSLAELQKYAERDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYNQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL150a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 89KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDEIHLKK KKEVTEKYEDDRRKDFKKIKSFSLAELQKYAERDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYNQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL151 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 90KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL151a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 91KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL152 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 92KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLEQLQKYADADLSVVEKLKEIIIQLVQEIYKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYNQKYYLAIMD KKHKKCLQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL152a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 93KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSSGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLEQLQKYADADLSVVEKLKEIIIQLVQEIYKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYNQKYYLAIMD KKHKKCLQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL153 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 94KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFSLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL153a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 95KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFSLEKSLKENEEVVKIMKDLLDSIKDFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL154 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 96KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKKVTEKYEDDRRKEFKKIESFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGKGEEDNRDESFYGDFNDAYDKL SKIDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL154a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 97KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKKVTEKYEDDRRKEFKKIESFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGKGEEDNRDESFYGDFNDAYDKLName Sequence SEQ SKIDHIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL155 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 98KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYAERDLSVVEKLKEIIIQLVQEIEKVYSTSDKL FDASFVLEKSLKENEEVVKIMKDLLDSLKDFERFIKAFLGSGEEDNRDESFYGDFVDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL155a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 99KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYAERDLSVVEKLKEIIIQLVQEIEKVYSTSDKL FDASFVLEKSLKENEEVVKIMKDLLDSLKDFERFIKAFLGSGEEDNRDESFYGDFVDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL156 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 100KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKDFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSDKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRKDQKYYLAIMD KKHKKCLQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL156a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 101KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKDFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSDKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRKDQKYYLAIMD KKHKKCLQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL157 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 102KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIYKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL157a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 103KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAQLQKYADRDLSVVEKLKEIIIQLVQEIYKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKDFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKNSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL159 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 104KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDKRRKDFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKEFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL159a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 105KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIYVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDKRRKDFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKENEEVVKIMKDLLDSIKEFERFIKAFLGSGEEDNRDESFYGDFNDAYDKL LKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHAKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL160 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 106KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL160a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 107KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL162 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 108KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPSTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDLLCS QNDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL162a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 109KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPSTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDLLCS QNDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL163 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 110KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDLLCS QDDKDFFASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL163a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 111KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDLLCS QDDKDFFASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL164 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 112KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL164a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 113KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL165 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 114KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL165a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 115KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL166 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 116KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKSDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCS QNDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL166a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 117KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKSDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCS QNDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL167 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 118KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL167a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 119KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL168 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 120KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQNGDIRDELCS QDDKEFFKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL168a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 121KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQNGDIRDELCS QDDKEFFKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL169 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 122KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL169a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 123KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL170 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 124KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKSDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKDFYASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL170a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 125KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKSDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWYTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKDFYASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL171 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 126KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKDFFASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL171a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 127KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKDFFASFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIEQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL172 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 128KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCS QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL172a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 129KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCS QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYEAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL173 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 130KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWLTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL173a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 131KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWLTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL186 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 132KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSGVKVEKQVYKKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL187 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 133KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGL KNSGVKVEKQVYKKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL188 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 134KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSGVKVEGQVYKKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL189 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 135KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIDRGEGNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSGVKVEKQVYKKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL190 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 136KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIDMGDRNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSGVKVEKQVTQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL191 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 137KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIDMGDRNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKKVTQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL322 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 138KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL322a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 139KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYDSNGIFVKNGPAISTISKDIFGEWSVIRDKWNAEYDDIHLKK KKEVTEKYEDDRRKEFKKIKSFSLAELQKYADRDLSVVEKLKEIIIQLVQEIEKVYSTSEKL FDASFVLEKSLKKNEEVVKIMKDLLDSIKEFERFIKAFLGSGTEDNRDESFYGDFNDAYDKL SKIDKIYDAIRNYVTQKPYSKDKFKLYFQNPQFMNGWDKDKETDYRATILRYGQKYYLAIMD KKHKKALQKIDKDDKSSNYEKMNYKLLPGPNKMLPKVFFSKKWMAYYNPSEEILKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSNPCASGGALKGYQITNKFESFKSMSTQNGFI FYIPAWLTSKIDPSTGFVNLLYTKYESIERSKKFISTFDRIMYVPERDLFEFALDYKNFQTT DADYIKKWKLYSYGNRIRIFRNPKKNNVFDWEEVCLTDKYKSLFNAYGINYENGDIRKLLCE QNDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNKEGIFYDSRNYEAQENAILPKNA DANGAYNIARKVLWAIRQFKQNEEEKLDKVKIAISNKEWLEYAQTSVK DL323 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 140KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL323a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 141KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL324 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 142KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQNGDIRDELCS QDDKEFFKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL324a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 143KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPEEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFALDYKNFPRT DADYIKKWILYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQNGDIRDELCS QDDKEFFKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL325 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 144KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNIDIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL325a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 145KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIMYVPEEDLFEFELDYKNFPRT DEDYIKKWVLYSYGSRIRKFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL326 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 146KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYVPAWLTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL326a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYLAFIE 147KVLNSIKLKNLQKYISLYRKDKRTEKENKELKKLEDKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEAKSTSIAYRIINENLTRFIDNI DIFEKVKKIFDKHEVQEIKKKILNSKYDVDDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALKGYQITNKFESFKSMSTQNGFI FYVPAWLTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFALDYKNFPRT DEDYIKKWVLYSYGSRIRIFRNPKKNNQWDYEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL327 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 148KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL327a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 149KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL328 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 150KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL328a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 151KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL329 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 152KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL329a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 153KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL330 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 154KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL330a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 155KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL331 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 156KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL331a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 157KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL332 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 158KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL332a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 159KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL333 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 160KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKYTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL333a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 161KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKYTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL334 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 162KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL334a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 163KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL335 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 164KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL335a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 165KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL336 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 166KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGSSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL336a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 167KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGSSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL337 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 168KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL337a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 169KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL338 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 170KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL338a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 171KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL339 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 172KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL339a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 173KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL340 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 174KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL340a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 175KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL341 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 176KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL341a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 177KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL342 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 178KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL342a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 179KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL343 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 180KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL343a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 181KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL344 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 182KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL344a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 183KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL345 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 184KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL345a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 185KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYIPAWNTSKIDPTTGFVNLLKTKYTTIEDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL346 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 186KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL346a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKNLLKEDEKRAEDYKEVKKLLDRYYRAFIE 187KVLSSIKLKNLQKYIDLFRKDKRTEKENKELKKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFENRKNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSKYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYPEKFTSDKEVLDVFRETLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVQEIYKVYGTSKSL FDRSFVLEKSLKQNSEVVAIMKELLDSVKEFEHYIKAFFGKGTEVERDEAFYGEFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMNGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSNNYEKINYKLLPGPNKMLPKVFFSKKWMQYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYLVDKKKDPNEPGGALHGYQITNKFESFKSMSTQNGFI FYVPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL347 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 188KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL347a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 189KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL348 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 190KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVKName Sequence SEQ DL348a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 191KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL349 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 192KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL349a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 193KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFName Sequence SEQ MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL350 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 194KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL350a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 195KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL351 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 196KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNIKIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDGName Sequence SEQ EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL351a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 197KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL352 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 198KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFIName Sequence SEQ FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL352a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKRLLKEDEKRAEDYKEVKKLLDRYYRAFIE 199KVLSSIKLKNLQKYIDLFRKDKRTEKENKELEKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFDNRENMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSDYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRNTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL353 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 200KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL353a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 201KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVNEIYKVYGNSKSL FDRSFVLEKSLKQNSDVVAIMKELLDSVKEFEHYIKAFFGKGTESERDEAFYGQFVLAYDILName Sequence SEQ LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSSNYEKINYKLLPGPNKMLPKVFFSKKWMSYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYMVDKKKDPNAPGGALHGYQITNKFESFKSMSTQNGFI FYIPAWNTSKIDPTTGFVNLLKTKYTTIADAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL354 SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 202KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYRATILRYDQKYYLAIMD KKYAKCLQKIDKDDVSGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDIQKIYKNGTF KKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKYKDIAGFYREVEEQGYKVSFE SASKKEVDKLVEEGKLYMFQIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELF MRRASLKKEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPK NIFKINTEVRVLLKHDDNPYVIGIARGERNLLYIVVVDGKGNIVEQYSLNEIINNFNGIRIK TDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICELVEKYDAVIALEDLNSGF KNSRVKVEKQVYQKFEKMLIDKLNYIVDKKKDPNDPGGALHGYQITNKFESFKSMSTQNGFI FYLPAWNTSKIDPTTGFVNLLKTKYTTIQDAKKFISKFDRIRYVPEEDLFEFELDYKNFPRT DADYIKKWVLYSYGSRIRKFRNPKKNNQWDWEEVDLTKAFKELFEKYGINYQDGDIRDELCK QDDKEFYKSFMSLMSLMLQMRNSIEGRTDVDFLISPVKNKNGIFYDSRNYKAQENAELPKNA DANGAYNIARKVLWAIDQFKKAEDEKLDKVKIAISNKEWLEYAQTSVK DL354a SKLEKFTNCYSLSKTLRFKAIPVGKTQENIDAKQLLKEDEKRAEDYKEVKKLLDRYYRAFIE 203KVLSSIKLKNLQKYIDLFRKDKRTEKENKELRKLQEKLRKEIAKAFKSHEGYKKLFKKDIIE EILPKFLDDKSEIELVESFKGFTTAFTGFFNNRNNMFSEEEKSTSIAYRIINENLTRFIDNI KIFEKVKKIFDKHEVQEIKEKILNSRYDVEDFFQGEFFNFVLTQEGIDVYNAIIGGFVTEDG EKIKGLNEYINLYNQKHKQKLPKFKPLYKQILSDRESLSFYGEKYTSDKEVLDVFRDTLNKN SEIFSSIKKLEKLFKNFDEYSSSGIFVKNGPAISSISKTIFGEWNVIREKWNNKYDDIHLKK KAVVTEKYEEKRRKEFKKIESFSLSELQEYASADLSVVQKLKEIIIDKVDEIYKVYGSSKSL FDRSFVLEKSLKQNSAVVAIMKELLDSVKEFEHYIKAFFGKGTETERDEAFYGDFVLAYDIL LKVDHIYDAIRNYVTQKPYSKTKFKLYFQNPQFMGGWDKNKETDYR...

Claims

CLAIMS1. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO:1 and comprises 15 or more, optionally all, of substitution mutations selected from N33A, V38K, G49E, S60A, N63E, D64K, N75Q, N76K, K84D, T85K, N96K, N100K, G111S, N112H, SI 17K, T126E, E130K, D136S, A139E, N142E, N145K, F173Y, C175I, Y183F, S185D, Ml 871, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, S388E, Q399E, D439S, S465E, K478T, S551Q, N575S, and S1157K, relative to SEQ ID NO: 1.

2. The polypeptide of claim 1, comprising 30 or more, optionally 40 or more of the substitution mutations.

3. The polypeptide of claim 1 or 2, further comprising one or more of substitution mutations selected from H67S / N, I99E / D, A334S / N, G393E / K, E398S / A, D450S / E, N468H / R, E476K / S, T967S / P, S1030T / K, S1053Q / P, S1093D / K, Q1108N / D, A1113K / D, SI 119N / D, DI 158E / N, and G1196R / D, relative to SEQ ID NO: 1.

4. The polypeptide of claim 3, further comprising one or more of substitution mutations selected from T346S, D350T, D360E, A364N, E365K, D383E, D384K, D405S, E412Q, Q420D, E433K, K434S, A438R, K448Q, D458E, N481E, S485A, D519T, D537N, and G550D, relative to SEQ ID NO: 1.

5. The polypeptide of any one of claims 1-4, further comprising one or more of substitution mutations selected from L59R, S79D, E98Q, A166E, and D188K, relative to SEQ ID NO: 1.

6. The polypeptide of claim 5, further comprising substitution mutation F1084W, relative to SEQ ID NO: 1.

7. The polypeptide of any one of claims 1-6, further comprising one or more of substitution mutations selected from K1015Y, T1019E, D1023R, E1040R, R1054T, A1094K, E1097S, K1101A, Q1107E, K1200Q, A1201N, andD1203E, relative to SEQ ID NO: 1.

8. The polypeptide of any one of claims 1-6, further comprising one or more of substitution mutations selected from C965NZE, K1064V / I, and E1117K / S, relative to SEQ ID NO:1.

9. The polypeptide of claim 8, further comprising one or more of substitution mutations selected from S962K, N963D, S1007T, S1020T, S1024A, N1070S, V1083Q, C1090D, Y1095F, N1100E, LI 114E, Al 122E, SI 125K, Al 129S, T1142E, El 168K, and II 174E, relative to SEQ ID NO: 1.

10. The polypeptide of claim 9, further comprising one or more substitution mutations selected from K972H, L1000N, and I1074K, relative to SEQ ID NO:1.

11. The polypeptide of any one of claims 1-10, further comprising mutations at one or more positions selected from R35, E95, D156, E159, D213, G291, Y294, N306, D423, S431, A451, T480, D489, G532, G576, A604, M957, A966, 1996, and A1022, relative to SEQ ID NO:1.

12. The polypeptide of claim 11, wherein the mutations are substitution mutations, optionally selected from R35N / Q, E95K / R, D156E / N, E159K / N, D213K / R, G291P, Y294F, N306E / D, D423Q / N, S431T / N, A451E / D, T480D / V / S, D489E / Q, G532N, G576N / S, A604Q / S, M957L / I, A966E / D, I996V / L, and A1022E / Q.

13. The polypeptide of claim 12, wherein the substitution mutations are selected from R35N, E95K, D156E, E159K, D213K, G291P, Y294F, N306E, D423Q, S431T, A451E, T480D / V, D489E, G532N, G576N, A604Q, M957L, A966E, I996V, and A1022E.

14. The polypeptide of claim 12, wherein the substitution mutations are selected from R35Q, E95R, D156N, E159N, D213R, N306D, D423N, S431N, A451D, T480S, D489Q, G576S, A604S, M957I, A966D, I996L, and A1022Q.

15. The polypeptide of claim 1 or 2, further comprising mutations at one or more positions selected from K1015, T1019, D1023, S1030, S1053, R1054, A1094, A1201, and DI 203, relative to SEQ ID NO:1.

16. The polypeptide of claim 15, wherein the mutations are substitution mutations, optionally selected from K1015Y, T1019E, D1023R, S1030T / K, S1053Q / P, R1054T, A1094K, A1201N, andD1203E.

17. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, S 1157K, D 1158E, G1196R, K 1200Q, A1201N, and D 1203E.

18. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, S60A, N63E, D64K, H67N, N75Q, N76K, F81Y, K84D, T85K, E95K, N96K, I99D, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, F173Y, C175I, Y183F, S185D, Ml 871, D194K, A195K, E207K, D213K, E217D, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, S1157K, D1158E, G1196R, K1200Q, A1201N, andD1203E.

19. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E,F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, S332D, A334N, N356S, A375K, V376E, S388E, G393K, E398A, Q399E, E402K, A406R, K421L, D423Q, Y426E, G430S, S431T, D439S, D450E, A451E, A454K, V463I, S465E, N468R, Y469F, F474L, E476S, K478T, T480D, V491N, L492D, I496K, L498S, V500I, H502K, G532N, S551Q, Y562H, A563K, C565A, V574K, N575S, G576S, I581M, D611E, Q613L, T967S, K1015Y, T1019E, A1022E, D1023R, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, SI 157K, DI 158E, G1196R, K1200Q, A1201N, andD1203E.

20. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D relative to SEQ ID NO: 1.

21. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N,G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965E, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, S1053P, K1064I, N1070S, I1074K, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, QI 108N, Al 113D, Lil 14E, El 117S, SI 119D, Al 122E, Y1124F, SI 125K, Al 129S, T 1142E, S 1157K, D 1158N, E 1168K, 11174E, and G1196D.

22. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, K972H, I996V, L1000N, S1007T, S1020T, A1022E, S1024A, S1030K, A1046E, S1053P, A1057E, K1064V, N1070S, I1074K, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

23. The polypeptide of any one of claims 1-13, wherein the polypeptide comprises substitution mutations selected from N33A, R35N, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156E, E159K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213K, E221Q, S248D, T266H, V280I, G291P, G293K, Y294F, E298K, E302D, N306E, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, M957L, S962K, N963D, C965N, A966E, T967P, I996V, S1007T, S1020T, A1022E, S1024A, S1030K, M1035R, S1053P, A1057E, K1064V, N1070S, V1083Q, F1084W, W1086Y, C1090D, S1093K, Y1095F, N1100E, Q1108D,A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

24. The polypeptide of any one of claims 1-10, wherein the polypeptide comprises substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, SI 024 A, SI 03 OK, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

25. The polypeptide of any one of claims 1-12 and 14, wherein the polypeptide comprises substitution mutations selected from N33A, R35Q, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, E95R, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, D156N, E159N, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, D213R, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, N306D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

26. The polypeptide of any one of claims 1-12 and 14, wherein the polypeptide comprises substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D,M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423N, S431N, E433K, K434S, A438R, D439S, K448Q, D450S, A451D, D458E, S465E, N468H, E476K, K478T, T480S, N481E, S485A, D489Q, D519T, D537N, G550D, S551Q, N575S, G576S, A604S, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, SI 119D, Al 122E, SI 125K, Al 129S, T1142E, S1157K, DI 158N, El 168K, Il 174E, and G1196D.

27. The polypeptide of any one of claims 1-12 and 14, wherein the polypeptide comprises substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, A604Q, S962K, N963D, C965N, T967P, K972H, L1000N, S1007T, S1020T, S1024A, S1030K, M1035R, A1046E, S1053P, K1064V, N1070S, I1074K, V1083Q, F1084W, C1090D, S1093K, Y1095F, N1100E, Q1108D, A1113D, L1114E, E1117K, S1119D, A1122E, S1125K, A1129S, T1142E, S1157K, D1158N, E1168K, I1174E, and G1196D.

28. The polypeptide of any one of claims 1-5, wherein the polypeptide comprises substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, H67S, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, I99E, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, T967S, S1030T, E1040R, S1O53Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E, Q1108N, A1113K, S1119N, S 1157K, D 1158E, G1196R, K 1200Q, A1201N, and D 1203E.

29. The polypeptide of any one of claims 1-4, wherein the polypeptide comprises substitution mutations selected from N33A, V38K, G49E, S60A, N63E, D64K, H67N, N75Q, N76K, F81Y, K84D, T85K, N96K, I99D, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, F173Y, C175I, Y183F, S185D, M187I, D194K, A195K, E207K, E217D, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D450S, D458E, S465E, N468H, E476K, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, T967S, S1030T, E1040R, S1053Q, R1054T, S1093D, A1094K, E1097S, K1101A, Q1107E,Q1108N, A1113K, S1119N, S 1157K, D 1158E, G1196R, K 1200Q, A1201N, and D 1203E.

30. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises mutations at three or more positions selected from S388, Q399, D439, S465, K478, S551, and N575, relative to SEQ ID NO: 1.

31. The polypeptide of claim 30, wherein the mutations are substitution mutations, optionally selected from S388E, Q399E, D439S, S465E, K478T, S551Q, andN575S, relative to SEQ ID NO: 1.

32. The polypeptide of claim 30 or 31, further comprising mutations at one or more positions selected from A334, G393, E398, D450, N468, and E476, relative to SEQ ID NO:1.

33. The polypeptide of claim 32, wherein the mutations are substitution mutations, optionally selected from A334N / S, G393K / E, E398A / S, D450E / S, N468R / H, and E476S / K.

34. The polypeptide of claim 33, wherein the substitution mutations are selected from A334N, G393K, E398A, D450E, N468R, and / or E476S.

35. The polypeptide of claim 33, wherein the substitution mutations are selected from A334S, G393E, E398S, D450S, N468H, and / or E476K.

36. The polypeptide of any one of claims 30-35, further comprising mutations at one or more positions selected from D423, S431, A451, T480, D489, G576, and A604, relative to SEQ IDNO:!.

37. The polypeptide of claim 36, wherein the mutations are substitution mutations, optionally selected from D423Q / N, S431T / N, A451E / D, T480D / V / S, D489E / Q, G576N / S, and A604Q / S.

38. The polypeptide of claim 37, wherein the substitution mutations are selected from D423Q, S431T, A451E, T480D / V, D489E, G576N, and A604Q.

39. The polypeptide of claim 37, wherein the substitution mutations are selected from D423N, S431N, A451D, T480S, D489Q, G576S, and / or A604S.

40. The polypeptide of any one of claims 30-33 and 35-38, wherein the polypeptide comprises substitution mutations selected from A334S, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, G393E, E398S, Q399E, D405S, E412Q, Q420D, D423Q, S431T, E433K, K434S, A438R, D439S, K448Q, D450S, A451E, D458E, S465E, N468H, E476K, K478T, T480V, N481E, S485A, D489E, D519T, G532N, D537N, G550D, S551Q, N575S, G576N, and A604Q.

41. The polypeptide of any one of claims 30-34 and 36-38, wherein the polypeptide comprises substitution mutations selected from S332D, A334N, N356S, A375K, V376E, S388E, G393K, E398A, Q399E, E402K, A406R, K421L, D423Q, Y426E, G430S, S431T, D439S, D450E, A451E, A454K, V463I, S465E, N468R, Y469F, F474L, E476S, K478T, T480D, V491N, L492D, I496K, L498S, V500I, H502K, G532N, S551Q, Y562H, A563K, C565A, V574K, N575S, G576S, I581M, D611E, and Q613L.

42. An RNA-guided DNA-binding polypeptide, wherein the polypeptide comprises any one of SEQ ID NOs:16, 18, 20, 22, 24, 26, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 232, 234, 236, 241, 243, 245, 247, 257, and 261.

43. The polypeptide of any one of claims 1-42, wherein the polypeptide is catalytically inactive, optionally comprising D832A, D832K, or D832L.

44. An RNA-guided DNA-binding polypeptide, wherein the polypeptide comprises SEQ IDNO:258 or 262.

45. The polypeptide of any one of claims 1-42, wherein the polypeptide is catalytically inactive, optionally comprising mutations at one or more positions selected from R833, E835, R836, F931, R935, K940, Q941, Y943, and Q944.

46. The polypeptide of claim 45, wherein the mutations are substitution mutations selected from R833M, E835D, R836G, F931L, R935G, K940G, Q941K, Y943T, and Q944K.

47. The polypeptide of claim 46, wherein the substitution mutations are Q944K and R935G.

48. The polypeptide of claim 46, wherein the substitution mutations are Q944K, F93 IL, and R935G.

49. The polypeptide of claim 46, wherein the substitution mutations are K940G, Q944K, and R935G.

50. The polypeptide of claim 46, wherein the substitution mutations are R836G, Q944K, and R935G.

51. The polypeptide of claim 46, wherein the substitution mutations are R833M, E835D, Y943T, and R935G.

52. The polypeptide of claim 46, wherein the substitution mutations are R833M, E835D, Y943T, and Q941K.

53. An RNA-guided DNA-binding polypeptide, wherein the polypeptide comprises any one of SEQ IDNOs:135, 219, 220, 221, 228, 229, 230, 250, 252, 259, 260, and 263-293.

54. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises substitution mutations at R935 and Q944, optionally wherein the substitution mutations are R935G and Q944K.

55. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises substitution mutations at F931, R935, and Q944, optionally wherein the substitution mutations are F931L, R935G, and Q944K.

56. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises substitution mutations at R935, K940, and Q944, optionally wherein the substitution mutations are R935G, K940G, and Q944K.

57. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises substitution mutations at R833, E835, Q941, and Y943, optionally wherein the substitution mutations are R833M, E835D, Q941K, and Y943T.

58. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO:1 and comprises 15 or more, optionally all, of substitution mutations selected from N33A, V38K, G49E, L59R, S60A, N63E, D64K, N75Q, N76K, S79D, K84D, T85K, N96K, E98Q, N100K, G111S, N112H, S117K, T126E, E130K, D136S, A139E, N142E, N145K, A166E, F173Y, C175I, Y183F, S185D, M187I, D188K, D194K, A195K, E221Q, S248D, T266H, V280I, G293K, E298K, E302D, T346S, D350T, D360E, A364N, E365K, D383E, D384K, S388E, Q399E, D405S, E412Q, Q420D, E433K, K434S, A438R, D439S, K448Q, D458E, S465E, K478T, N481E, S485A, D519T, D537N, G550D, S551Q, N575S, S962K, N963D, S1007T, S1020T, S1024A, N1070S, V1083Q, F1084W, C1090D, Y1095F, N1100E, LI 114E, Al 122E, SI 125K, Al 129S, T1142E, SI 157K, El 168K, and II 174E, relative to SEQ ID NO: 1.

59. The polypeptide of claim 58, further comprising one or more of substitution mutations selected from C965N / E, K1064V / I, and E1117K / S, relative to SEQ ID NO: 1.

60. The polypeptide of claim 59, further comprising one or more substitution mutations selected from K972H, L1000N, and I1074K, relative to SEQ ID NO:1.

61. The polypeptide of any one of claims 58-60, further comprising mutations at one or more positions selected from R35, E95, D156, E159, D213, G291, Y294, N306, D423, S431, A451, T480, D489, G532, G576, A604, M957, A966, 1996, and A1022, relative to SEQ ID NO:1.

62. The polypeptide of claim 61, wherein the mutations are substitution mutations, optionally selected from R35N / Q, E95K / R, D156E / N, E159K / N, D213K / R, G291P, Y294F, N306E / D, D423Q / N, S431T / N, A451E / D, T480D / V / S, D489E / Q, G532N, G576N / S, A604Q / S, M957L / I, A966E / D, I996V / L, and A1022E / Q.

63. The polypeptide of claim 62, wherein the substitution mutations are selected from R35N, E95K, D156E, E159K, D213K, G291P, Y294F, N306E, D423Q, S431T, A451E, T480D / V, D489E, G532N, G576N, A604Q, M957L, A966E, I996V, and A1022E.

64. The polypeptide of claim 62, wherein the substitution mutations are selected from R35Q, E95R, D156N, E159N, D213R, N306D, D423N, S431N, A451D, T480S, D489Q, G576S, A604S, M957I, A966D, I996L, and A1022Q.

65. A RNA-guided DNA-binding polypeptide having a catalytically active DNA nuclease (aRGDP), wherein the polypeptide is a variant of SEQ ID NO:1and comprises substitution mutations S1030K and / or S1053P.

66. An RNA-guided DNA-binding polypeptide, wherein the polypeptide is a variant of SEQ ID NO: 1 and comprises substitution mutation D832K or D832L.

67. A fusion protein comprising:(a) a RNA-guided DNA-binding polypeptide having a catalytically inactive DNA nuclease (dRGDP), whereinthe polypeptide is a variant of SEQ ID NO: 1 anddoes not comprise substitution mutations at any one of positions D832, E925, D947, and DI 180, or a combination thereof; andeither (i) does not comprise substitution mutations at positions S1030 and S1053, or (ii) comprises substitution mutations S1030K and S1053P; and(b) a nucleotide deaminase domain.

68. The fusion protein of claim 67, wherein the polypeptide further comprises:(i) substitution mutations R836G, Q944K, and R935G; or(ii) substitution mutations R833M, E835D, Y943T, and Q941K.

69. A fusion protein comprising the polypeptide of any one of the preceding claims and a base editing domain, optionally wherein the base editing domain is a nucleobase deaminase;a DNA methyltransferase (DNMT) domain and / or a domain that recruits a DNMT, a demethylase domain (e.g., TET) domain,a transcriptional repressor domain,a transcriptional activator domain,a nuclease domain,a transpose, recombinase, or integrase domain,a reverse transcriptase domain, ora histone modifier domain.

70. The fusion protein of any one of claims 67-69, further comprising a uracil glycosylase inhibitor (UGI).

71. The fusion protein of any one of claims 67-70, further comprising one or more nuclear localization signal (NLS), optionally selected from an SV40 NLS, a nucleoprotein (NP) NLS, and a bipartite (BP) NLS.

72. The fusion protein of any one of claims 67-71, further comprising one or more linker(s).

73. A nucleic acid molecule encoding the polypeptide of any one of claims 1-66 or the fusion protein of any one of claims 67-72.

74. The nucleic acid molecule of claim 73, further encoding a crRNA.

75. The nucleic acid molecule of claim 74, wherein the crRNA comprises SEQ ID NO: 586.

76. An expression vector comprising the nucleic acid molecule of any one of claims 73-75, optionally wherein the expression vector is a viral expression vector, further optionally selected from an adenoviral vector, an adeno-associated viral vector, and a lentiviral vector.

77. The expression vector of claim 76, wherein the adenoviral vector is a helper dependent adenoviral (HD Ad) vector.

78. The expression vector of claim 77, wherein the HD Ad vector has a CD46-binding adenoviral capsid.

79. The expression vector of claim 78, wherein the CD46-binding adenoviral capsid of the HD Ad vector is an Ad5 / 35 capsid.

80. The expression vector of claim 78, wherein the CD46-binding adenoviral capsid of the HD Ad vector is an Ad5 / 35++ capsid.

81. A delivery system comprising the nucleic acid molecule of any one of claims 73-75, optionally wherein the delivery system comprises lipid nanoparticles (LNPs).

82. A cell comprisinga target nucleic acid comprising a target strand and a non-target strand;a crRNA or a nucleic acid encoding a crRNA that binds to the targetstrand; andthe fusion protein of any one of claims 67-72, the nucleic acid molecule of any one of claims 73-75, the expression vector of any one of claims 76-80, or the delivery system of claim 81.

83. A method of editing or regulating a target gene in a cell, comprising introducing the cell:the fusion protein of any one of claims 67-72, the nucleic acid molecule of any one ofclaims 73-75, the expression vector of any one of claims 76-80, or the delivery system of claim 81, anda crRNA that binds the target gene or a nucleic acid encoding the crRNA.

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