Bacteria TRIZ Cases
- MacB Transporter Enhances O-Phosphoserine Export Yield
Identified MacB and YggT proteins export O-phosphoserine efficiently, resolving low secretion rates that limit L-cysteine production yields.
- Recombinant Pseudomonas plecoglossicida for L-xylose Production
Replacing acid hydrolysis with biological fermentation, the strain eliminates sulfuric acid waste while achieving 57.3% glucose transformation.
- Methanogenesis Nutrient Adsorption Management
Non-adsorbable nutrients like urea maintain bioavailability in coal seams, resolving toxicity trade-offs to boost sustained methane generation rates.
- Engineered Pseudomonas putida for Stable Xylose and Galactose Metabolism
Engineered Pseudomonas putida strains utilize heterologous chromosomal pathways to metabolize xylose and galactose efficiently.
- Escherichia yigL Gene Deletion for L-Tryptophan Production
Deleting the yigL gene prevents PLP decomposition, maintaining intracellular concentrations that increase L-tryptophan yield by up to 60%.
- Pseudomonas monteilii 9-2 for Petroleum Hydrocarbon Degradation in Saline-Alkali Environments
Pseudomonas monteilii 9-2 degrades petroleum hydrocarbons using specialized metabolic pathways adapted to high salinity and alkalinity.
- Microorganism Fermentation for 3-Hydroxyadipic Acid Production
Culturing specific microorganisms to produce 3-hydroxyadipic acid via metabolic pathways, resolving low productivity in existing microbial methods.
- Nano-sized Kimchi Lactic Acid Bacteria for Intestinal Absorption
Nano-sized kimchi lactic acid bacteria bypass conventional low survival rates by enabling direct intestinal wall absorption to treat colorectal diseases.
- Daikenchuto Dosage Prediction via Intestinal Flora Bacteroidetes Firmicutes Ratio
Analyzing intestinal flora ratios predicts Daikenchuto effectiveness and guides dosage adjustments.
- Streptomyces HS7522 Strain for Milbemycin A4 Fermentation
A Streptomyces HS7522 strain produces milbemycin A4 via optimized fermentation.
- Sporulation-Inhibiting Substance for Bacterial Culture Productivity
Adding a sporulation-inhibiting substance prevents premature metabolic switching, allowing extended vegetative growth and higher spore productivity.
- Recombinant Listeria Vaccine with Mutant PrfA for HPV
Recombinant Listeria strain carrying mutant PrfA protein resolves safety and efficacy trade-off by inducing E7-specific CTLs while reducing virulence.
- Probiotic Growth via Fermented Lactic Acid Bacterial Culture
Fermented lactic acid bacterial culture promotes probiotic microorganism growth through specific strain metabolites.
- Altered Polymerases for High-Fidelity Fast Sequencing
Recombinant polymerase mutations enable rapid nucleotide incorporation while maintaining high sequencing fidelity.
- Recombinant Microorganism for Direct Soil Contamination Measurement
A self-dying recombinant strain visualizes aromatic hydrocarbon toxicity via fluorescence changes in environmental samples.
- Engineered Polynucleotide Vector for High-Capacity Biological Library Generation
Engineered polynucleotide vectors with specific cloning sites produce ultra-high-capacity libraries with uniform sequence distribution.
- Two-Fluid Nozzle Lipid Dispersion for Microbial Culture
Atomizing molten lipids via gas injection overcomes coagulation issues and boosts microbial assimilation.
- Engineered Bacterial Strains for Threonine Production via Machine Learning
Machine learning models predict optimal strain configurations to increase threonine yield while reducing exhaustive experimental testing complexity.
- GMP Synthase Variant Engineering for Purine Nucleotide Production
Amino acid substitutions in glutamine-hydrolyzing GMP synthase increase XMP conversion rates, resolving low productivity bottlenecks in microbial biosynthesis.
- EP5 Promoter and Hypothetical Protein Mutations for Corynebacterium Lysine Fermentation
Replacing wild-type promoters with EP5 variants and mutating hypothetical proteins to resolve fermentation yield limits in Corynebacterium.
- Heterologous Beta-Glucosidase Expression in Yeast for Cellulose Hydrolysis
Heterologous beta-glucosidase expression in Saccharomyces cerevisiae enhances specific enzymatic activity for cellulose breakdown.
- Co-culturing Microorganisms for Demethylation Efficiency
Combining demethylating Eubacterium with lactic acid bacteria regenerates tetrahydrofolic acid cofactors to boost demethylation efficiency.