Method for determining inversion time in vascular imaging, magnetic resonance imaging method and apparatus

Abstract

The application relates to a method for determining inversion time in blood vessel imaging, a magnetic resonance imaging method and a device. The method for determining inversion time in blood vessel imaging comprises the following steps: selecting an imaging position from a blood vessel imaging area; at the imaging position, collecting at least two blood vessel images with different inversion times by using an inversion time searching technology; obtaining an inversion time corresponding to a blood vessel image with optimal blood vessel display; and determining a time point for setting a longitudinal magnetization to zero according to the inversion time corresponding to the blood vessel image with optimal blood vessel display. The magnetic resonance imaging method comprises the following steps: determining an inversion time based on the method for determining inversion time in blood vessel imaging; applying a regional selection inversion pulse at an imaging position; and applying a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image. The method can optimize the inversion time, thereby obtaining optimal blood vessel display.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of magnetic resonance angiography, in particular to a method for determining inversion time in non-contrast angiography, a magnetic resonance imaging method and device. BACKGROUND

[0002] Magnetic resonance imaging (MRI) has been more and more widely used in clinical diagnosis and scientific research, and has advantages of safety, multiple contrast, and good resolution of soft tissue. In the early development and application of magnetic resonance imaging, non-contrast enhanced magnetic resonance angiography (NCEMRA) was restricted due to longer acquisition time and image artifacts compared with contrast-enhanced MRA using gadolinium. However, in recent years, due to technological progress and concerns about the safety of gadolinium, imaging techniques without contrast agents have received renewed attention.

[0003] In non-contrast angiography, there is a class of spin labeling angiography techniques, among which inflow spin labeling technique can be used for imaging of blood vessels such as renal artery and hepatic portal vein. The imaging method uses a fast imaging sequence, and before the fast imaging sequence, a selected layer inversion recovery (IR) preparation pulse is applied to suppress the signal in the IR layer, and the fast imaging sequence is acquired after waiting for the inversion time (TI). Due to the inflow of blood outside the IR layer, the inflowing blood is not affected by the IR, and the desired blood vessel signal is obtained in the imaging layer, while the static tissue signal is suppressed by the IR.

[0004] However, the effectiveness of this imaging technique is highly dependent on the setting of TI time. If the TI time is too long, the static tissue signal is completely recovered, and the static tissue signal in the image is too strong to affect the observation of the blood vessel signal. If the TI time is too short, the slow blood flow cannot completely flow into the imaging area, and the blood signal is too low to also affect the display of the blood vessel signal. Due to the physiological differences of individuals, there is no regularity in the selection of TI value, and this imaging technique is highly dependent on the selection of TI, so a technique for measuring a suitable TI value is needed. SUMMARY

[0005] Therefore, it is necessary to provide a method for determining inversion time in angiography, a magnetic resonance imaging method and device capable of obtaining inversion time in order to solve the above technical problems.

[0006] A method for determining inversion time in angiography, the method for determining inversion time in angiography comprises:

[0007] selecting an imaging position from a blood vessel imaging area;

[0008] At the imaging position, at least two blood vessel images with different inversion times are acquired by using inversion time searching technique;

[0009] An inversion time corresponding to a blood vessel image with optimal blood vessel display in the blood vessel images is obtained.

[0010] An inversion time corresponding to a blood vessel image with optimal blood vessel display in the blood vessel images is obtained.

[0011] In one embodiment, the selecting the imaging position from the blood vessel imaging region comprises:

[0012] At least one imaging position is selected from the blood vessel imaging region.

[0013] The obtaining of the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel images comprises:

[0014] An inversion time corresponding to a blood vessel image with optimal blood vessel display in each blood vessel image corresponding to each imaging position is obtained.

[0015] A target inversion time is calculated according to the obtained inversion times.

[0016] In one embodiment, the acquiring at least two blood vessel images with different inversion times at the imaging position by using inversion time searching technique comprises:

[0017] At the imaging position, at least two blood vessel images with different inversion times are acquired by using TI-SCOUT technique in cardiac delayed enhancement imaging.

[0018] In one embodiment, the acquiring at least two blood vessel images with different inversion times at the imaging position by using inversion time searching technique comprises:

[0019] After the inversion pulse is selected in each region, partial K-space data of multiple images is acquired, and complete K-space data sets of multiple images are acquired by using multiple region selection inversion pulses.

[0020] At least two blood vessel images with different inversion times are reconstructed according to the complete K-space data sets.

[0021] In one embodiment, the acquiring at least two blood vessel images with different inversion times at the imaging position by using inversion time searching technique comprises:

[0022] At the imaging position, at least two blood vessel images with different inversion times are acquired by using inversion time searching technique through a fast imaging sequence.

[0023] A magnetic resonance imaging method, the magnetic resonance imaging method comprising:

[0024] determining the inversion time based on the above-mentioned method for determining inversion time in vessel imaging;

[0025] applying a region-selective inversion pulse at the imaging location;

[0026] applying a target imaging sequence at the imaging location after the inversion time to obtain a target magnetic resonance image.

[0027] A device for determining inversion time in vessel imaging, the device comprising:

[0028] an imaging location determining module configured to select an imaging location from a vessel imaging region;

[0029] a vessel image acquiring module configured to acquire at least two vessel images with different inversion times at the imaging location using inversion time search technique;

[0030] a first inversion time determining module configured to obtain an inversion time corresponding to a vessel image in which vessels are optimally displayed;

[0031] a time point determining module configured to determine a time point at which longitudinal magnetization is zeroed according to the inversion time corresponding to the vessel image in which vessels are optimally displayed.

[0032] A magnetic resonance imaging device, the device comprising:

[0033] a second inversion time determining module configured to determine the inversion time based on the above-mentioned device for determining inversion time in vessel imaging;

[0034] a region-selective inversion pulse applying module configured to apply a region-selective inversion pulse at the imaging location;

[0035] a fast imaging sequence applying module configured to apply a target imaging sequence at the imaging location after the inversion time to obtain a target magnetic resonance image.

[0036] A computer device comprising a memory and a processor, the memory storing a computer program, and the processor implementing the steps of the method described in any one of the above-mentioned embodiments when executing the computer program.

[0037] A computer readable storage medium having stored thereon a computer program, the computer program implementing the steps of the method described in any one of the above-mentioned embodiments when executed by a processor.

[0038] The blood vessel imaging inversion time determination method, the magnetic resonance imaging method and the device determine the imaging position first, and then acquire at least two blood vessel images with different inversion times through the inversion time search technology, compare the blood vessel images to determine the optimal blood vessel image, and take the inversion time of the optimal blood vessel image as the inversion time for blood vessel imaging, so that the optimal blood vessel display is obtained through the optimization of the inversion time. BRIEF DESCRIPTION OF DRAWINGS

[0039] Figure 1 An application environment diagram of the blood vessel imaging inversion time determination method in an embodiment;

[0040] Figure 2 A flowchart of the blood vessel imaging inversion time determination method in an embodiment;

[0041] Figure 3 A schematic diagram of the imaging principle in an embodiment;

[0042] Figure 4 A sequence diagram of the region selection inversion pulse in an embodiment;

[0043] Figure 5 A schematic diagram of the K-space segmentation technology principle in an embodiment;

[0044] Figure 6 A sequence diagram of the target imaging sequence in an embodiment;

[0045] Figure 7 A flowchart of the magnetic resonance imaging method in an embodiment;

[0046] Figure 8 A structural block diagram of the blood vessel imaging inversion time determination device in an embodiment;

[0047] Figure 9 A structural block diagram of the magnetic resonance imaging device in an embodiment;

[0048] Figure 10 An internal structure diagram of the computer device in an embodiment. DETAILED DESCRIPTION

[0049] In order to make the purpose, technical scheme and advantages of the present application clearer, further detailed description will be given to the present application in combination with the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, and are not used to limit the present application.

[0050] The blood vessel imaging inversion time determination method and the magnetic resonance imaging method provided by the present application can be applied to, for example, Figure 1The application environment is shown. Among them, the terminal 102 communicates with the medical imaging device 104 through the network. Among them, the terminal 102 selects an imaging position from the blood vessel imaging area, and then the terminal 102 sends an imaging sequence to the medical imaging device 104, so that the terminal 102 collects at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technology, so that the terminal obtains the inversion time corresponding to the blood vessel image with the best blood vessel display in the blood vessel image. Optionally, the positioning image can be obtained by pre-scanning the blood vessel imaging area, and the imaging position can be selected on the positioning image, and then at least two blood vessel images with different inversion times are collected by using the inversion time search technology, so that the best blood vessel image is determined by comparing the blood vessel images, and the inversion time of the best blood vessel image is used as the inversion time of the blood vessel imaging, and the inversion time is optimized, so that the best blood vessel display is obtained.

[0051] Among them, the terminal 102 can be but not limited to various personal computers, notebook computers, smart phones, tablet computers, portable wearable devices and functional modules and special circuits of the medical imaging device itself. In this embodiment, the terminal 102 can include a mobile terminal device of a patient and / or a mobile terminal device of a medical operator. The medical imaging device 104 includes but is not limited to various imaging devices, such as CT imaging devices (CT: Computed Tomography, which is a cross-sectional scanning of a certain part of the human body by using a precisely collimated X-ray beam and a highly sensitive detector, and through CT scanning, a precise three-dimensional position image of a tumor can be reconstructed), magnetic resonance devices (which is a kind of tomography, which obtains electromagnetic signals from the human body by using magnetic resonance phenomenon, and reconstructs human body information image), Positron Emission Computed Tomography devices, Positron Emission Computed Tomography / Magnetic Resonance Imaging System (PET / MR) and the like.

[0052] In one embodiment, as Figure 2 shown, a method for determining inversion time in blood vessel imaging is provided, and the method is applied to the terminal in Figure 1 for example, including the following steps:

[0053] S202: Select an imaging position from the blood vessel imaging area.

[0054] Specifically, the imaging position is a position in the blood vessel imaging area, in combination with Figure 3 shown, wherein the imaging area is the blood vessel imaging area, and the imaging position is selected in the area to collect blood vessel images. Optionally, the imaging position can be set at the center of the blood vessel imaging area, both ends of the blood vessel imaging area, etc.

[0055] S204: At the imaging location, at least two vascular images with different inversion times are acquired using time-reversal search technology.

[0056] Specifically, the time-inversion search technique (also known as the time-inversion detection technique) is used to acquire at least two vascular images with different inversion times, thereby determining the optimal inversion time based on the quality of the vascular images at different inversion times. Optionally, the time-inversion search technique can be the TI-SCOUT technique in cardiac time-intensity contrast imaging, that is, using the TI-SCOUT technique in cardiac time-intensity contrast imaging at the imaging location to acquire at least two vascular images with different inversion times.

[0057] Among them, see Figure 4 As shown, the inversion time (TI) refers to the time from the inversion recovery (IR) pulse to the equivalent center of the excitation pulse (Ex) at the center line of the acquisition K-space, i.e., the time interval from the midpoint of the 180-degree inversion pulse to the equivalent center point of the excitation pulse at the center line of the acquisition K-space. In this embodiment, the 180-degree inversion pulse reverses the longitudinal magnetization vector Mz from the positive Z-axis to the negative Z-axis, the dephasing gradient dephasing the transverse magnetization vector, and then the longitudinal magnetization vector recovers from the negative Z-axis to the positive Z-axis. After waiting for a certain time (satisfying the definition of TI), the imaging sequence is applied and magnetic resonance signals (data) are acquired. After image reconstruction, the final magnetic resonance image is obtained. During the inversion time TI, blood vessels and static tissues are suppressed by the region-selective inversion pulse, while the blood flowing into the blood vessel segment is not affected by the region-selective inversion pulse. Therefore, the desired bright blood vessel signal is obtained at the imaging level, while the static tissue signal is suppressed by IR. Thus, the degree of suppression of static tissue and the degree of fresh blood inflow vary with different inversion times. Only when the static tissue is suppressed to the point that it does not affect the display of blood vessels can the best vascular imaging effect be obtained.

[0058] S206: Obtain the inversion time corresponding to the blood vessel image with the best blood vessel display in the blood vessel image.

[0059] S208: Determine the time point for setting the longitudinal magnetization to zero based on the reversal time corresponding to the optimal blood vessel image in the blood vessel image.

[0060] Specifically, after obtaining multiple frames of blood vessel images corresponding to different inversion times TI, the terminal can determine the optimal blood vessel image through a blood vessel image recognition algorithm, so that the terminal determines the inversion time TI corresponding to the last blood vessel image as the target inversion time. The blood vessel image recognition algorithm can be pre-trained and used to score each blood vessel image to select the blood vessel image with the highest score as the optimal blood vessel image. The blood vessel image recognition algorithm can be trained according to blood vessel images pre-scored by humans. For example, the higher the clarity of the blood vessel image, the higher the human score; the lower the clarity of the blood vessel image, the lower the human score. Alternatively, the terminal can use image segmentation techniques (such as threshold-based methods) and region growing methods to display the optimal blood vessel image from the blood vessel image.

[0061] In one embodiment, the blood vessel image with the optimal blood vessel display is determined by: performing enhancement filtering on the blood vessel image to obtain an enhanced filtered image; and segmenting the enhanced filtered image based on at least one preset segmentation threshold to obtain a candidate region corresponding to the preset segmentation threshold, and the set of the connected candidate regions being the blood vessel image with the optimal blood vessel display.

[0062] In other embodiments, the terminal can also output the blood vessel image for manual selection, that is, manually selecting the optimal blood vessel image, and then the terminal determines the inversion time TI corresponding to the last blood vessel image as the target inversion time. After the target inversion time is determined, the target inversion time ends, that is, the time point at which the longitudinal magnetization is zeroed.

[0063] The above-mentioned blood vessel imaging inversion time determination method first determines the imaging position, then acquires at least two blood vessel images with different inversion times through inversion time searching technology, compares the blood vessel images to determine the optimal blood vessel image, and determines the inversion time of the optimal blood vessel image as the inversion time for blood vessel imaging. By optimizing the inversion time, the optimal blood vessel display is obtained. The embodiments of the present application can calculate the real inversion time for different patients and different tissue-specificities, and the algorithm has strong adaptability and good robustness.

[0064] In one embodiment, selecting an imaging position from a blood vessel imaging region includes: selecting at least one imaging position from the blood vessel imaging region, such as the center of the blood vessel region, the upper and lower ends of the blood vessel region, and the like. Obtaining the inversion time corresponding to the blood vessel image with the optimal blood vessel display includes: obtaining the inversion time corresponding to the blood vessel image with the optimal blood vessel display for each imaging position, respectively; and calculating the target inversion time according to the obtained inversion times.

[0065] Specifically, in combination with Figure 3The at least one imaging position can be selected in the blood vessel imaging region. In an embodiment, the at least one imaging position is evenly distributed in the blood vessel imaging region. In this way, the target inversion time can be calculated by taking the average of the inversion times.

[0066] Specifically, the terminal can obtain multiple blood vessel images at different imaging positions by using the inversion time search technique, and determine the optimal blood vessel image corresponding to each imaging position, and then determine the inversion time corresponding to each imaging position. Finally, the terminal can determine the target inversion time in the blood vessel imaging according to the statistical quantity of the inversion time corresponding to each imaging position. For example, the average of the inversion time corresponding to each imaging position is calculated as the target inversion time. Taking the average is to make all the blood vessels in the imaging region show well. Other minimum or maximum may not make some blood vessels show well.

[0067] In the above embodiment, the inversion time search technique is used at multiple imaging positions in the blood vessel imaging region to determine the optimal inversion time corresponding to each imaging position, and then the average of the multiple optimal inversion times is obtained for blood vessel imaging. In this way, all the blood vessels in the imaging region can show well.

[0068] In one embodiment, referring to Figure 5 At the imaging position, at least two blood vessel images with different inversion times are acquired by using the inversion time search technique, including: after selecting the inversion pulse in each region, acquiring partial K-space data of multiple images, and acquiring complete K-space data sets of multiple images using multiple region selection inversion pulses; and reconstructing at least two blood vessel images with different inversion times according to the complete K-space data sets.

[0069] Specifically, the partial K-space data is acquired by using the K-space segmentation technique, in which the data of multiple time points (phases) is required for one layer of image. Since the time of one cardiac cycle is limited, it cannot acquire all the multi-phase data of one layer. Therefore, only part of the data of a certain phase is acquired in one cardiac cycle, and the partial K-space data of each phase is acquired through multiple adjacent cardiac cycles. Finally, the complete K-space data set is obtained by combining all the partial K-space data. In short, the complete K-space data set required for reconstructing one complete image is divided into multiple segments, and only part of the data of a certain phase is acquired in each sequence cycle. The acquisition of the entire K-space data is completed through multiple sequence cycles.

[0070] In combination with Figure 5As shown in the figure, after each region selection inversion pulse, a plurality of image frames of partial K-space data are collected, wherein K11, K21, ···, KN1 in the figure represent K-space data collected after different inversion times after the first region selection inversion pulse; K1M, K2M, ···, KNM represent K-space data collected after different inversion times after the Mth region selection inversion pulse, N is the number of image frames, and M is the number of regions. The K-space data collected after corresponding to the same inversion time is filled into the same K-space, so that the entire complete K-space data set is collected by a plurality of region selection inversion pulses. Finally, the terminal reconstructs at least two blood vessel images of different inversion times according to the complete K-space data set. Optionally, during the collection of the K-space data, electrocardio monitoring can also be applied. The electrocardio motion curve of the detection object is obtained through the electrocardio monitoring, and the abnormal heart cycle caused by the arrhythmia of the detection object is identified through the electrocardio motion curve. For the case of abnormal heart cycle, re-collection is performed.

[0071] wherein Figure 5 In the above embodiment, the K-space segmentation technology is used to improve the time resolution, so that the subsequent inversion time determination is more accurate.

[0072] In the above embodiment, the K-space segmentation technology is used to improve the time resolution, so that the subsequent inversion time determination is more accurate.

[0073] In one of the embodiments, at the imaging position, at least two blood vessel images of different inversion times are collected by using the inversion time searching technology, including: at the imaging position, at least two blood vessel images of different inversion times are collected by using the inversion time searching technology through the fast imaging sequence.

[0074] Specifically, in combination with Figure 6 as shown in the figure, Figure 6A schematic diagram of a target imaging sequence in one embodiment, in which the sequence is selected as a gradient echo based balanced steady state free precession sequence (GRE_bSSFP). RF is the applied excitation radio frequency pulse, GS is the gradient pulse. GP is the applied phase encoding gradient, which needs to be applied 128 times repeatedly, and the amplitude varies linearly, GR is the frequency encoding gradient, signal is the resulting gradient echo or balanced steady state free precession gradient echo.

[0075] Wherein the generation of the blood vessel image is based on the signal acquired after the excitation of the fast imaging sequence, which acquires low resolution images multiple times, and then determines the optimal parameter value according to the acquired images.

[0076] In the above embodiment, the fast imaging sequence is used to acquire low resolution images multiple times, and then the optimal parameter value is determined according to the acquired images, which improves the determination efficiency of the inversion time.

[0077] In one embodiment, as shown in Figure 7 , a magnetic resonance imaging method is provided, and the method is applied to a terminal in Figure 1 for example, which includes the following steps:

[0078] S702: Determine the inversion time based on the blood vessel imaging inversion time determination method in any one of the above embodiments.

[0079] Specifically, the determination method of the inversion time can be referred to the above, which will not be repeated here.

[0080] S704: Apply a region selection inversion pulse at the imaging position.

[0081] Specifically, the imaging position here is a certain position in the blood vessel imaging region.

[0082] S706: After the inversion time, apply a target imaging sequence at the imaging position to obtain a target magnetic resonance image.

[0083] Specifically, after applying the region-selective inversion pulse, and after a time inversion period, the target imaging sequence is applied at the imaging location. At this point, the static tissue signal is suppressed by the region-selective inversion pulse, and the remaining signal is the signal of the inflowing blood, which is a bright signal. Therefore, a relatively accurate target magnetic resonance image containing vascular images can be obtained. Optionally, the target imaging sequence can be a non-contrast-based vascular imaging sequence such as a time-flight (TOF) sequence, a phase-contrast (PC) sequence, a steady-state free precession (SSFP) sequence, or an arterial spin labeling (ASL) sequence.

[0084] It should be understood that, although Figure 2 , Figure 7 The steps in the flowchart are shown sequentially as indicated by the arrows, but these steps are not necessarily executed in the order indicated by the arrows. Unless otherwise specified herein, there is no strict order in which these steps are executed, and they can be performed in other orders. Figure 2 , Figure 7 At least some of the steps in the process may include multiple steps or multiple stages. These steps or stages are not necessarily completed at the same time, but may be executed at different times. The execution order of these steps or stages is not necessarily sequential, but may be executed in turn or alternately with other steps or at least some of the steps or stages in other steps.

[0085] In one embodiment, such as Figure 8 As shown, a time-reversal determination device for vascular imaging is provided, comprising: an imaging position determination module 801, a vascular image acquisition module 802, a first time-reversal determination module 803, and a time point determination module 804, wherein:

[0086] The imaging location determination module 801 is used to select an imaging location from the blood vessel imaging region;

[0087] The vascular image acquisition module 802 is used to acquire at least two vascular images with different reversal times at the imaging location using a time-reversal search technique.

[0088] The first reversal time determination module 803 is used to obtain the reversal time corresponding to the blood vessel image with the best blood vessel display in the blood vessel image;

[0089] The timing determination module 804 is used to determine the timing point at which the longitudinal magnetization is set to zero based on the reversal time corresponding to the optimal blood vessel image in the blood vessel image.

[0090] In one of the embodiments, the imaging position determination module 801 is configured to select at least two imaging positions from the blood vessel imaging region;

[0091] The first inversion time determination module 803 comprises:

[0092] A first inversion time acquisition unit is configured to acquire an inversion time corresponding to a blood vessel image with optimal blood vessel display in a blood vessel image corresponding to each imaging position, respectively.

[0093] A target inversion time determination unit is configured to calculate a target inversion time according to the acquired inversion time.

[0094] In one of the embodiments, the blood vessel image acquisition module 802 is configured to acquire at least two blood vessel images with different inversion times at the imaging position by using the TI-SCOUT technology in the cardiac delayed enhancement imaging.

[0095] In one of the embodiments, the blood vessel image acquisition module 802 comprises:

[0096] A K-space data acquisition unit is configured to acquire partial K-space data of multiple images after selecting inversion pulses in each region, and acquire complete K-space data sets of the multiple images by using multiple region selection inversion pulses.

[0097] A blood vessel image generation unit is configured to reconstruct at least two blood vessel images with different inversion times according to the complete K-space data sets.

[0098] In one of the embodiments, the blood vessel image acquisition module 802 is configured to acquire at least two blood vessel images with different inversion times at the imaging position by using the inversion time searching technology through a fast imaging sequence.

[0099] In one of the embodiments, as shown in Figure 9 , a magnetic resonance imaging device is provided, comprising: a second inversion time determination module 901, a region selection inversion pulse application module 902, and a target imaging sequence application module 903, wherein:

[0100] The second inversion time determination module 901 is configured to determine the inversion time by the inversion time determination device in the blood vessel imaging in any one of the embodiments.

[0101] The region selection inversion pulse application module 902 is configured to apply a region selection inversion pulse at the imaging position.

[0102] The target imaging sequence application module 903 is configured to apply a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image.

[0103] The specific definitions of the inversion time determination apparatus in blood vessel imaging and the blood vessel imaging apparatus can refer to the definitions of the inversion time determination method in blood vessel imaging and the blood vessel imaging method in the foregoing, which will not be repeated here. Each module in the inversion time determination apparatus in blood vessel imaging and the blood vessel imaging apparatus can be realized by software, hardware, or a combination thereof, in whole or in part. Each module can be embedded in or independent of a processor in a computer device in hardware form, or can be stored in a memory in the computer device in software form, so as to be called and executed by the processor to perform the operations corresponding to each module.

[0104] In one embodiment, a computer device, which can be a terminal, has an internal structure diagram as shown in Figure 10 The computer device includes a processor, a memory, a communication interface, a display screen, and an input device connected by a system bus. The processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for running the operating system and the computer program in the non-volatile storage medium. The communication interface of the computer device is configured to perform wired or wireless communication with an external terminal. The wireless communication can be achieved by WIFI, a carrier network, NFC (Near Field Communication), or other technologies. The computer program is executed by the processor to implement an inversion time determination method in blood vessel imaging and a blood vessel imaging method. The display screen of the computer device can be a liquid crystal display screen or an electronic ink display screen. The input device of the computer device can be a touch layer overlaid on the display screen, or a key, trackball, or touchpad arranged on the housing of the computer device, or an external keyboard, touchpad, or mouse, etc.

[0105] Those skilled in the art can understand that Figure 10 The structure shown in the foregoing is only a block diagram of part of the structure related to the scheme of the present application, and does not constitute a limitation on the computer device to which the scheme of the present application is applied. A specific computer device can include more or fewer components than those shown in the diagram, or combine certain components, or have a different arrangement of components.

[0106] In one embodiment, a computer device includes a memory and a processor. The memory stores a computer program. The processor executes the computer program to implement the following steps: selecting an imaging position from a blood vessel imaging region; at the imaging position, collecting at least two blood vessel images with different inversion times by using an inversion time search technique; obtaining an inversion time corresponding to a blood vessel image in which the blood vessels are best displayed; and determining a time point at which longitudinal magnetization is set to zero according to the inversion time corresponding to the blood vessel image in which the blood vessels are best displayed.

[0107] In one embodiment, the processor executes the computer program to select the imaging position from the blood vessel imaging region, including: selecting at least two imaging positions from the blood vessel imaging region; the processor executes the computer program to obtain the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image, including: obtaining the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image corresponding to each imaging position respectively; and calculating the target inversion time according to the obtained inversion time.

[0108] In one embodiment, the processor executes the computer program to collect at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: collecting at least two blood vessel images with different inversion times at the imaging position by using the TI-SCOUT technique in the cardiac delayed enhancement imaging.

[0109] In one embodiment, the processor executes the computer program to collect at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: after selecting the inversion pulse for each region, collecting partial K-space data of multiple images to collect complete K-space data sets for selecting inversion pulses for multiple regions; and reconstructing at least two blood vessel images with different inversion times according to the complete K-space data sets.

[0110] In one embodiment, the processor executes the computer program to collect at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: at the imaging position, collecting at least two blood vessel images with different inversion times by using the inversion time search technique through a fast imaging sequence.

[0111] In one embodiment, a computer device is provided, including a memory and a processor, the memory stores a computer program, and the processor executes the computer program to implement the following steps: determining the inversion time based on the inversion time determination method in any one of the above embodiments; applying a region selection inversion pulse at the imaging position; and applying a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image.

[0112] In one embodiment, a computer readable storage medium is provided, which stores a computer program, and the computer program is executed by a processor to implement the following steps: selecting an imaging position from a blood vessel imaging region; collecting at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique; obtaining the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image; and determining the time point at which the longitudinal magnetization is zeroed according to the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image.

[0113] In one embodiment, the computer program, when executed by the processor, involves selecting the imaging position from the blood vessel imaging region, including: selecting at least two imaging positions from the blood vessel imaging region; the computer program, when executed by the processor, involves obtaining the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image, including: obtaining the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel image corresponding to each imaging position respectively; and calculating the target inversion time according to the obtained inversion time.

[0114] In one embodiment, the computer program, when executed by the processor, involves acquiring at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: acquiring at least two blood vessel images with different inversion times at the imaging position by using the TI-SCOUT technique in cardiac delayed enhancement imaging.

[0115] In one embodiment, the computer program, when executed by the processor, involves acquiring at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: after selecting the inversion pulse in each region, acquiring partial K-space data of multiple images, acquiring complete K-space data set of multiple images using multiple region selection inversion pulses; and reconstructing at least two blood vessel images with different inversion times according to the complete K-space data set.

[0116] In one embodiment, the computer program, when executed by the processor, involves acquiring at least two blood vessel images with different inversion times at the imaging position by using the inversion time search technique, including: at the imaging position, acquiring at least two blood vessel images with different inversion times by using the inversion time search technique through a fast imaging sequence.

[0117] In one embodiment, a computer readable storage medium is provided, and the computer readable storage medium stores a computer program. The computer program, when executed by the processor, implements the following steps: determining the inversion time based on the inversion time determination method in any one of the above embodiments; applying a region selection inversion pulse at the imaging position; and applying a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image.

[0118] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program. The computer program can be stored in a non-volatile computer readable storage medium, and when executed, can include the processes of the above-mentioned embodiment methods. Any reference to memory, storage, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory or optical memory. Volatile memory can include random access memory (RAM) or external cache memory. As an illustration but not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).

[0119] Any combination of the technical features of the above embodiments can be made. In order to make the description simple, all possible combinations of the technical features in the above embodiments are not described, but as long as the combination of the technical features does not exist, it should be considered as the scope of the present application.

[0120] The above embodiments only express several implementation manners of the present application, and the description is more specific and detailed, but it should not be understood as a limitation on the scope of the patent. It should be pointed out that for those skilled in the art, without departing from the concept of the present application, some modifications and improvements can be made, which are all within the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. A method for determining inversion time in vascular imaging, characterized by, The method for determining inversion time in blood vessel imaging comprises: selecting an imaging position from a blood vessel imaging region; acquiring at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique; acquiring an inversion time corresponding to a blood vessel image with optimal blood vessel display in the blood vessel images; determining a time point for setting longitudinal magnetization to zero according to the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel images; the acquiring at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique comprises: after applying a region selection inversion pulse in a cardiac cycle, acquiring partial K-space data of multiple images, each partial K-space data corresponding to a different inversion time after the region selection inversion pulse; filling K-space data acquired after different cardiac cycles corresponding to the same inversion time into the same K-space to acquire complete K-space data sets of the multiple images; reconstructing at least two blood vessel images with different inversion times according to the complete K-space data sets.

2. The method of inversion time determination in angiography of claim 1, wherein, the selecting an imaging position from a blood vessel imaging region comprises: selecting at least one imaging position from the blood vessel imaging region; the acquiring an inversion time corresponding to a blood vessel image with optimal blood vessel display in the blood vessel images comprises: acquiring an inversion time corresponding to a blood vessel image with optimal blood vessel display in each blood vessel image corresponding to each imaging position; calculating a target inversion time according to the acquired inversion time.

3. The method of inversion time determination in angiography of claim 1, wherein, the acquiring at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique comprises: acquiring at least two blood vessel images with different inversion times at the imaging position by using a TI-SCOUT technique in cardiac delayed enhancement imaging.

4. The method of any one of claims 1 to 3, wherein, the acquiring at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique comprises: acquiring at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique through a fast imaging sequence.

5. A magnetic resonance imaging method characterized by, the magnetic resonance imaging method comprises: determining an inversion time based on the method for determining inversion time in blood vessel imaging according to any one of claims 1 to 4; applying a region selection inversion pulse at the imaging position; applying a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image.

6. An inversion time determination apparatus in vascular imaging, characterized by the device for determining inversion time in blood vessel imaging comprises: an imaging position determination module configured to select an imaging position from a blood vessel imaging region; a blood vessel image acquisition module configured to acquire at least two blood vessel images with different inversion times at the imaging position by using an inversion time searching technique, which comprises: after applying a region selection inversion pulse in a cardiac cycle, acquiring partial K-space data of multiple images, each partial K-space data corresponding to a different inversion time after the region selection inversion pulse; filling K-space data acquired after different cardiac cycles corresponding to the same inversion time into the same K-space to acquire complete K-space data sets of the multiple images; and reconstructing at least two blood vessel images with different inversion times according to the complete K-space data sets. The first inversion time determination module is configured to obtain an inversion time corresponding to a blood vessel image with optimal blood vessel display in the blood vessel images. The time point determination module is configured to determine a time point for setting the longitudinal magnetization to zero according to the inversion time corresponding to the blood vessel image with optimal blood vessel display in the blood vessel images.

7. The inversion time determination apparatus for blood vessel imaging according to claim 6, wherein, The imaging position determination module is configured to select at least one imaging position from the blood vessel imaging region. The first inversion time determination module comprises a first inversion time acquisition unit and a target inversion time determination unit. The first inversion time acquisition unit is configured to obtain an inversion time corresponding to a blood vessel image with optimal blood vessel display in a blood vessel image corresponding to each imaging position respectively. The target inversion time determination unit is configured to obtain a target inversion time according to the obtained inversion time.

8. A magnetic resonance imaging apparatus, characterized by The magnetic resonance imaging device comprises: The second inversion time determination module is configured to determine an inversion time based on the blood vessel imaging inversion time determination device of claim 6 or 7. The region selection inversion pulse application module is configured to apply a region selection inversion pulse at the imaging position. The fast imaging sequence application module is configured to apply a target imaging sequence at the imaging position after the inversion time to obtain a target magnetic resonance image. 9.A computer device, comprising a memory and a processor, wherein the memory stores a computer program, and the computer device is configured to perform the method according to any one of claims 1-8 when the computer program is executed by the processor. The processor executes the computer program to implement the steps of the method of any one of claims 1 to 5.

10. A computer-readable storage medium having stored thereon a computer program, characterized in that, The computer program is executed by the processor to implement the steps of the method of any one of claims 1 to 5.

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