A selenium disulfide stable emulsification system, uses and shampoo

Abstract

The application belongs to the field of daily chemicals, and particularly relates to a selenium disulfide stable emulsification system, and a preparation method of pre-dispersed selenium disulfide. The preparation method comprises the following steps: mixing selenium disulfide, glycerol and polysaccharide to be homogeneous, and then adding an amphoteric ion surfactant to prepare pre-dispersed selenium disulfide. The polysaccharide is a polysaccharide having a thickening function in water. The emulsification system adopts glycerol and xanthan gum to pre-disperse and wrap selenium disulfide, so that the selenium disulfide can be suspended by sorbitan triisostearate with three hydrophobic groups. After the formula of the application is used, the emulsifier in the emulsion can be selected more widely. Meanwhile, it is found in the formula development process that sorbitan triisostearate has very good moisturizing effect on the scalp, and the problem of increased dandruff and itching caused by the use of selenium disulfide shampoo by dry scalp users can be solved by using sorbitan triisostearate. Meanwhile, the application also provides application of the emulsification system and a shampoo.

Description

Technical Field

[0001] The invention belongs to the field of daily chemicals, and particularly relates to a selenium disulfide stable emulsification system, application and shampoo. Background Art

[0002] The scalp is the soil of hair, and only a healthy scalp can produce healthy hair. Scalp problems such as oily scalp, dandruff, itching, and hair loss have long plagued us. Consequently, shampoos with anti-dandruff and anti-itching properties have consistently enjoyed a high market share.

[0003] Currently, the anti-dandruff agents in anti-dandruff shampoos on the market primarily include zinc pyrithione (ZPT), piroctone olamine (OCT), and climbazole (CLM). In addition, newer anti-dandruff agents such as dipotassium glycyrrhizate, potassium hexamidine di(hydroxyethylsulfonate), and plant anti-dandruff factors are also available. In recent years, an increasing number of shampoo and conditioner products have been developed using selenium disulfide as an anti-dandruff ingredient. Addressing the stability of selenium disulfide in products is a key consideration in formulation. Selenium disulfide can significantly inhibit bacteria and control oil production, but its use in formulations can lead to issues such as discoloration, odor change, and precipitation. Furthermore, dandruff is not solely caused by excessive oiliness and Malassezia furfur growth. For dry scalps, excessive dryness of the scalp after using selenium disulfide shampoo can also cause dandruff and itchiness. Therefore, addressing the issue of excessive dryness of the scalp after using selenium disulfide is a key technical issue that needs to be addressed.

[0004] Regarding the stability problem of selenium disulfide, those skilled in the art have long discovered it. For example, CN118436555A discloses a method for encapsulating selenium disulfide with a chitosan quaternary ammonium salt and its use in shampoo. While selenium disulfide is inexpensive, it is difficult to dissolve in water or disperse in a system, making it difficult to formulate in shampoo and thus not widely used in shampoo products. The method uses a chitosan quaternary ammonium salt to encapsulate selenium disulfide, which not only reduces the amount of selenium disulfide used and reduces scalp irritation, but also utilizes the quaternary ammonium salt chitosan to absorb into the hair, enhancing the deposition of selenium disulfide on the hair or scalp, thereby enhancing the anti-dandruff effect of selenium disulfide. CN117883322A describes a selenium disulfide shampoo and its preparation method, which uses a suspension stabilizing protective agent to help stabilize the selenium disulfide, solving the problems of selenium disulfide shampoo's short-lasting foam and prone to stratification, discoloration, and precipitation. The suspension stabilizing protective agent is a combination of three or more of colloidal sulfur, hydrogenated castor oil, disodium lauryl sulfosuccinate, zinc pyrrolidone carboxylate (Zinc PCA), methyl monoethanolamide cocoate (cocamidomethyl MEA), and starch hydroxypropyltrimethylammonium chloride. CN115887294A describes a selenium disulfide shampoo and its preparation method, which uses a high-molecular polymer such as an acrylic acid (ester) copolymer to suspend the selenium disulfide. CN116251026A describes an anti-dandruff shampoo and its preparation method, which uses sodium lignin sulfonate, sodium lauryl sulfate, coconut oil, and propylene glycol to suspend the selenium disulfide. CN114788788A discloses a selenium disulfide encapsulation technology and a selenium disulfide shampoo, which uses salicylic acid, a silane coupling agent, and silicone oil to suspend selenium disulfide.

[0005] Among the products on the market, most mature products use high molecular weight polymers, such as carbomer, to suspend selenium disulfide. The use of carbomer-type suspension stabilizers in the formula will increase the astringency of flushing water.

[0006] Using surfactants to suspend selenium disulfide is an effective method for suspending selenium disulfide without increasing the astringency of flushing water. However, the use of surfactants for suspension is limited in the choice of surfactants. For example, CN117883322A only allows for a combination of three or more of colloidal sulfur, hydrogenated castor oil, disodium lauryl sulfosuccinate, zinc pyrrolidone carboxylate (Zinc PCA), methyl monoethanolamide cocoate (cocamidomethyl MEA), and hydroxypropyltrimonium chloride. This poses a challenge to the selectivity of formulation applications.

[0007] In addition, the inability of selenium disulfide to be well applied to the treatment of dry scalp dandruff is also a problem that has not been solved in this field.

[0008] The technical problems to be solved in this case are: how to make selenium disulfide suitable for removing dandruff from dry scalp and how to improve the applicability of selenium disulfide formula. Summary of the Invention

[0009] In response to the shortcomings of the prior art, the present invention aims to provide a stable emulsion system for selenium disulfide. The emulsification system uses glycerin and xanthan gum to pre-disperse and encapsulate selenium disulfide, so that it can be suspended by sorbitan triisostearate, which has three hydrophobic groups. After using the formula of the present invention, the emulsifier in the emulsion can be more selective. At the same time, during the formulation development process, it was found that sorbitan triisostearate has an excellent moisturizing effect on the scalp. By using sorbitan triisostearate, the problems of increased dandruff and itchy scalp caused by selenium disulfide shampoo for users with dry scalp can be solved.

[0010] At the same time, the invention also provides application of the emulsification system and shampoo.

[0011] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:

[0012] A selenium disulfide stable emulsification system comprising an emulsifier, water, pre-dispersed selenium disulfide, and an inorganic salt for adjusting the viscosity of the emulsification system;

[0013] The method for preparing the pre-dispersed selenium disulfide is as follows: selenium disulfide is mixed homogeneously with glycerol and polysaccharide, and then a zwitterionic surfactant is added to prepare the pre-dispersed selenium disulfide; the polysaccharide is a polysaccharide having a thickening function in water;

[0014] The emulsifier contains sorbitan triisostearate;

[0015] The weight ratio of selenium disulfide, glycerol and polysaccharide is 0.1-1.1:1.5-2.5:0.1-0.5;

[0016] Preferably, the weight ratio of selenium disulfide, glycerol and polysaccharide is 0.8-1.1:1.5-2.5:0.1-0.5.

[0017] In the formulation of the present invention, glycerin is used to disperse selenium disulfide, allowing the surface of the selenium disulfide to fully bind to the glycerin, which is beneficial for the full dispersion of the selenium disulfide and the uniform encapsulation of the selenium disulfide by the polysaccharide. The polyhydroxy structure on the surface of the polysaccharide can fully bind to the glycerin on the surface of the selenium disulfide, and finally the encapsulation of the selenium disulfide is achieved through the zwitterionic surfactant. When this encapsulation structure is used in conjunction with sorbitan triisostearate, sorbitan triisostearate, due to its three hydrophobic segments, can stably suspend the inclusion. At the same time, this encapsulation structure can also achieve sustained release and stability of selenium disulfide, reducing scalp irritation. In addition, the excellent moisturizing and hydrating effect of sorbitan triisostearate itself further reduces the irritation of selenium disulfide to dry scalps, avoiding the problems of increased dandruff and itchy scalps caused by users with dry scalps using this product.

[0018] During some experiments of the present invention, we found that when other surfactants with suspending function were used to replace sorbitan triisostearate, they neither showed good suspension performance for selenium disulfide nor such excellent low irritation; such as using sodium stearoyl lactylate or C8-C14 alkyl glucoside (described in CN111643433A, an oil-control and anti-dandruff shampoo composition). We believe that the fundamental reason is that sorbitan triisostearate has three hydrophobic segments.

[0019] At the same time, by verifying other suspending surfactants with three hydrophobic segments, such as trihydroxystearin, we found that although it can suspend pre-dispersed selenium disulfide well, it is not as suitable as sorbitan triisostearate in people with dry scalp.

[0020] Through the solution of the present invention, the selection of the emulsifier of the present invention is diversified, and the user group of the shampoo is expanded.

[0021] In the above-mentioned selenium disulfide stable emulsion system, the weight ratio of sorbitan triisostearate to selenium disulfide is 2.5-3.5:0.1-1.1.

[0022] Preferably, the weight ratio of sorbitan triisostearate to selenium disulfide is 2.5-3.5:0.8-1.1.

[0023] In the above-mentioned selenium disulfide stabilized emulsification system, the emulsifier further comprises one or more combinations of anionic surfactants and nonionic surfactants.

[0024] In the above-mentioned selenium disulfide stabilized emulsification system, the anionic surfactant is one or more combinations of sodium laureth sulfate (70%), disodium lauryl sulfosuccinate (30wt%), sodium C14-16 olefin sulfonate (35wt%), and ammonium laureth sulfate (70wt%);

[0025] The nonionic surfactant is one or more combinations of cocamide MEA, ethylene glycol distearate, cocamide DEA, and cocamide MIPA;

[0026] The zwitterionic surfactant is one or more combinations of cocamidopropyl hydroxysulfonyl betaine, cocamidopropyl betaine, and lauryl betaine;

[0027] The active content of the anionic surfactant in the formula is 10-15 wt %; the amount of the nonionic surfactant is 0.5-2 wt %.

[0028] In the above-mentioned selenium disulfide stable emulsification system, the inorganic salt is sodium chloride.

[0029] In the above-mentioned selenium disulfide-stabilized emulsification system, the content of selenium disulfide is 0.8-1.1 wt%; and the polysaccharide is xanthan gum or guar gum.

[0030] In the above-mentioned selenium disulfide stable emulsification system, the mass ratio of the zwitterionic surfactant to selenium disulfide is 3-5:0.8-1.1.

[0031] At the same time, the present invention also discloses the use of any of the above-mentioned selenium disulfide stable emulsification systems for preparing shampoo products.

[0032] Finally, the present invention also discloses a shampoo comprising any of the above-described selenium disulfide stabilized emulsion systems; the selenium disulfide stabilized emulsion system further comprises one or more combinations of hair conditioners, silicones, fungicides, moisturizers, preservatives, chelating agents, pH regulators, and sodium chloride.

[0033] In the above-mentioned shampoo, the hair conditioning agent is one or more combinations of guar hydroxypropyltrimonium chloride, polyquaternium-10, polyquaternium-7, and polyquaternium-22; the silicone is one or more combinations of emulsified silicone oil, aminosilicone emulsion, and polyether-modified silicone oil; the bactericide and humectant is one or more combinations of colloidal sulfur, piroctone olamine salt, and climbazole; the chelating agent is one or more combinations of etidronate, disodium EDTA, and sodium hexametaphosphate; and the pH adjuster is one or more combinations of citric acid, sodium hydroxide, and sodium citrate.

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] The emulsification system of the present invention uses glycerin and xanthan gum to pre-disperse and encapsulate selenium disulfide, allowing it to be suspended by sorbitan triisostearate, which has three hydrophobic groups. After using the formula of the present invention, the emulsifier in the emulsion can be more selective. At the same time, during the formulation development process, it was discovered that sorbitan triisostearate has an excellent moisturizing effect on the scalp. By using sorbitan triisostearate, the problems of increased dandruff and itchy scalp caused by selenium disulfide shampoo for users with dry scalp can be solved.

[0036] Through the solution of the present invention, the selection of the emulsifier of the present invention is diversified, and the user group of the shampoo is expanded. DETAILED DESCRIPTION

[0037] The technical solution of the present invention is further described below by way of specific embodiments. It should be understood by those skilled in the art that the embodiments are merely to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0038] Source of raw materials:

[0039] Guar hydroxypropyltrimonium chloride: Kunshan Jingkun Oilfield Chemical Technology Co., Ltd., raw material model cationic guar gum JK140K;

[0040] Polyquaternium-10: Aivie (Zhongshan) Biotechnology Co., Ltd., Filfix 910;

[0041] Ethylenediaminetetraacetic acid: DEQUEST Italmatch Chemicals, raw material model Turpinal SL;

[0042] Sodium lauryl polyoxyethylene sulfate: Guangdong Licheng Aowei Industry Co., Ltd., raw material model RSAW ESB70 / ZA;

[0043] Cocamidopropyl hydroxysultaine: Guangzhou Huayu Fine Chemical Co., Ltd., raw material model FS CHSB-35;

[0044] Cocamide MEA: Zhongshan Kemide Oils and Fats Chemical Co., Ltd., C3-A (Cocamide MEA);

[0045] Sorbitan triisostearate: Guangzhou Meibo Ya Chemical Co., Ltd., MBY-313;

[0046] Colloidal sulfur: Rui Meng (Shanghai) Trade Co., Ltd., Sulfidal TM Colloidal Sulfur Cosmetic Grade;

[0047] Selenium sulfide: Salius Pharma Pvt Ltd., Selenium sulfide;

[0048] Glycerin: Fengyi Oils and Fats Technology (Dongguan) Co., Ltd., refined glycerin 100%;

[0049] Xanthan gum: BASF (China) Co., Ltd., Verdessence TM Xanthan;

[0050] Ethylene glycol distearate: Foshan Shihua Xinxin Material Co., Ltd., COL EGDS T;

[0051] Emulsified silicone oil: Wacker Chemical (China) Co., Ltd., DM 6124E;

[0052] Sodium chloride: Jiangxi Ershier Salt Industry Co., Ltd., refined salt;

[0053] Citric acid: Weifang Yingxuan Industry Co., Ltd., raw material model anhydrous citric acid.

[0054] Preparation of the first part of the emulsifying system

[0055] The preparation method of the emulsification system is as follows:

[0056] Step 1: Add deionized water to the container;

[0057] Step 2: Add surfactant and thickener to step 1, heat to 85-90°C, and stir for 30 minutes until the raw materials are completely dissolved;

[0058] Step 3: Pre-disperse 1g of glycerol and 0.95g of selenium disulfide, then mix 1g of glycerol and 0.3g of xanthan gum, heat and dissolve, cool to below 48°C, mix the two phases, homogenize at 3000r / min for 3min, add 4g of cocamidopropyl hydroxysulfobetaine, stir evenly, and set aside;

[0059] Step 4: Cool the solution in step 2 to below 48°C, add the solution in step 3, and stir for 20 minutes until the raw materials are completely dissolved;

[0060] Step 5: Adjust the pH to 5.0-5.5 with citric acid (10 wt% concentration) and add sodium chloride to adjust the consistency.

[0061] The formulations of the surfactants of Examples 1-4 are shown in Table 1;

[0062] Table 1 Recipe

[0063]

[0064] The water added to 100 in Table 1 means that the total weight of the emulsified system is controlled to be 100 g.

[0065] Examples 5 to 8 refer to the dosage of the surfactant in Example 1. By changing the formula of the pre-dispersed selenium disulfide in step 3, the effects of the dosage and selection of the pre-dispersed selenium disulfide on the performance are explored, with reference to Table 2;

[0066] Table 2 Recipe

[0067]

[0068] Comparative Example 5

[0069] The method is substantially the same as Example 1, except that step 3 is different. Specifically, step 3 is as follows: first, 1 g of ethylene glycol and 0.95 g of selenium disulfide are pre-dispersed, then 1 g of ethylene glycol and 0.3 g of xanthan gum are mixed and heated to dissolve, and then the mixture is cooled to below 48° C., the two phases are mixed, and homogenized at a speed of 3000 r / min for 3 min, 4 g of cocamidopropyl hydroxysulfobetaine is added, stirred evenly, and set aside.

[0070] Comparative Example 6

[0071] The method is substantially the same as Example 1, except that step 3 is different. Specifically, step 3 is as follows: first, 1 g of glycerol and 0.95 g of selenium disulfide are pre-dispersed, then 1 g of glycerol and 0.3 g of carbomer are mixed and heated to dissolve, and then the mixture is cooled to below 48° C., the two phases are mixed, and homogenized at a speed of 3000 r / min for 3 min, 4 g of cocamidopropyl hydroxysulfobetaine is added, stirred evenly, and set aside.

[0072] Comparative Example 7

[0073] The process is substantially the same as Example 1, except that sodium stearoyl lactylate is used in place of sorbitan triisostearate in an amount equal in weight.

[0074] Comparative Example 8

[0075] The process is substantially the same as Example 1, except that an equal amount of C8-C14 alkyl glucoside is used to replace sorbitan triisostearate.

[0076] Comparative Example 9

[0077] The process is substantially the same as Example 1, except that trihydroxystearin is used in place of sorbitan triisostearate in an equal amount by weight.

[0078] Performance Testing

[0079] 1. Selenium disulfide dispersion stability test

[0080] The selenium disulfide shampoos prepared in the above examples and comparative examples were stored at room temperature, 48°C, -18°C, and 5°C for three months each. The properties of the samples under each storage condition were examined before and after storage. The test results can be found in Table 3.

[0081] Table 3 Stability test results

[0082]

[0083]

[0084]

[0085] Result analysis:

[0086] 1. The results of Examples 1 to 9 show that by varying the dosage of different surfactants, the type of polysaccharide, and the selection of zwitterionic surfactants, the system stability can be maintained at an optimal state, effectively inhibiting the precipitation of selenium disulfide.

[0087] 2. By transverse comparison of Examples 1 to 4 and Comparative Examples 1 to 4, it can be seen that when sorbitan triisostearate is absent, it cannot exhibit good anti-precipitation effect in any storage state, which shows that sorbitan triisostearate mainly plays a role of suspension wrapper in the surface active system;

[0088] It can be seen from Comparative Examples 7 to 9 that the selection of the suspending agent is also important, and it can be concluded that the suspending agent with three hydrophobic chain segments contributes most to the stability of the system.

[0089] 3. It can be seen from Comparative Examples 6 and 7 that the selection of the polyol has little effect on the stability of the system, and the selection of the type of thickening agent has a relatively obvious effect. Although the acrylic thickening agent has more carboxyl groups, compared with the wrapping angle of the pre-dispersed selenium disulfide, it is obviously better to use polysaccharide.

[0090] 2. Dry scalp applicability test

[0091] Select 40 subjects with dry scalp, dandruff and itching, and divide them into 8 groups, i.e. 5 subjects in each group. Through the use effect test screening of the 8 cases, finally 40 subjects aged 18-55 years are statistically analyzed. The use method is as follows: after wetting the hair, take an appropriate amount of shampoo and evenly apply it on the hair, gently rub to generate abundant foam, massage the hair and clean the hair, then rinse and dry. The continuous use of the formula sample is 3-5 times, and the evaluation is in the form of score. The evaluation index is: 1 point for "very disagree", 2 points for "agree", 3 points for "general", 4 points for "agree", and 5 points for "very agree".

[0092] The scoring statistical results are shown in Table 4;

[0093] Table 4 Dry scalp applicability test results

[0094]

[0095] Result analysis: From the above experimental results, the following conclusions can be drawn:

[0096] 1. For the type of polysaccharide, the effect of xanthan gum is better than that of guar gum in terms of use feeling;

[0097] 2. The decisive condition for the feeling of dry hair / scalp users is the selection and use of the suspending agent.

[0098] From the above two test methods, it can be clearly known that the technical scheme of the present application can improve the stability of the system, prevent precipitation, and at the same time, can widely expand the application group of selenium disulfide, which has obvious commercial value.

[0099] Part 2 Application Formulation Testing

[0100] The application formula is shampoo, and its specific formula is shown in Table 5. Its preparation method is as follows:

[0101] Step 1: Add deionized water, guar hydroxypropyltrimonium chloride, and polyquaternium-10, stir for 3 minutes, and then add etidronic acid;

[0102] Step 2: Add sodium laureth sulfate, cocamide MEA, sorbitan triisostearate, and ethylene glycol distearate, heat to 85-90°C, and stir for 30 minutes until the ingredients are completely dissolved;

[0103] Step 3: Pre-disperse 1% glycerol and selenium disulfide, then mix 1% glycerol and xanthan gum, heat and dissolve, cool to below 48°C, mix the two phases, homogenize at 3000 rpm for 3 minutes, add cocamidopropyl hydroxysulfobetaine, and stir evenly;

[0104] Step 4: Cool to below 48°C, add colloidal sulfur, emulsified silicone oil, preservative and the pretreatment solution from step 3, and stir for 20 minutes until the raw materials are completely dissolved.

[0105] Step 5: Adjust the pH to 5.0-5.5 with citric acid (10% concentration) and add sodium chloride to adjust the consistency.

[0106] Table 5 Recipe

[0107]

[0108]

[0109] Performance Testing

[0110] 1. Stability test (high temperature, low temperature, high and low temperature cycle): The formula samples were placed in 48℃, 5℃, -18℃, -18~48℃ high and low temperature cycle test to test the stability of the product. The inspection period was 3 months, and there was no abnormality in stability.

[0111] 2. Volunteer testing:

[0112] A total of 33 subjects were enrolled, aged 18-55 years. After wetting hair, apply an appropriate amount of shampoo evenly to the hair and gently rub until a rich lather forms. Massage and cleanse the hair, then rinse thoroughly. Use for 4 weeks, twice weekly. Refer to Table 6 for test results and Table 7 for volunteer information.

[0113] Table 6 Summary of evaluation results of subjects using the product for 28 consecutive days

[0114]

[0115]

[0116] Table 7 Volunteer Information

[0117]

[0118]

[0119] Evaluation index: 1: "Strongly disagree", 2: "Agree", 3: "Neither agree nor disagree", 4: "Agree", 5: "Strongly agree"

[0120] After using the test product for four weeks, 90.91% of the subjects found the shampoo to have good foaming properties, 93.94% found it to have a conditioning effect, 96.97% found it to be easy to rinse, 100% found their hair to be more voluminous and less sticky, 96.97% found it to have an anti-dandruff effect, 96.97% found it to have an anti-itching effect, and 93.94% found it to have a less dry scalp. The product is suitable for all scalp types.

[0121] The applicant declares that while the above-described embodiments illustrate the process of the present invention, the present invention is not limited to the above-described process steps, nor does it imply that the present invention must rely on the above-described process steps for implementation. Those skilled in the art should understand that any improvements to the present invention, equivalent substitutions for the raw materials used, additions of auxiliary ingredients, and selection of specific methods, etc., fall within the scope of protection and disclosure of the present invention.

Claims

1. A selenium disulfide stable emulsification system, characterized in that: The invention comprises an emulsifier, water, pre-dispersed selenium disulfide and an inorganic salt for adjusting the viscosity of the emulsified system; The method for preparing the pre-dispersed selenium disulfide is as follows: selenium disulfide is homogenized with glycerol and polysaccharide, and then a zwitterionic surfactant is added to prepare the pre-dispersed selenium disulfide; the polysaccharide is a polysaccharide having a thickening function in water; the polysaccharide is xanthan gum; The emulsifier contains sorbitan triisostearate, anionic surfactant and nonionic surfactant; The weight ratio of selenium disulfide, glycerol and polysaccharide is 0.1-1.1:1.5-2.5:0.1-0.5; The weight ratio of sorbitan triisostearate to selenium disulfide is 2.5-3.5:0.1-1.1; The anionic surfactant is one or more of sodium laureth sulfate, disodium lauryl sulfosuccinate, sodium C14-16 olefin sulfonate, and ammonium laureth sulfate; The nonionic surfactant is one or more combinations of cocamide MEA, ethylene glycol distearate, cocamide DEA, and cocamide MIPA; The zwitterionic surfactant is one or more combinations of cocamidopropyl hydroxysulfonyl betaine, cocamidopropyl betaine, and lauryl betaine; The active content of the anionic surfactant in the formula is 10-15wt%; the amount of the nonionic surfactant is 0.5-2wt%; The mass ratio of the zwitterionic surfactant to selenium disulfide is 3-5:0.8-1.

1.

2. The selenium disulfide stable emulsification system according to claim 1, characterized in that The inorganic salt is sodium chloride.

3. The selenium disulfide stable emulsion system according to claim 1 or 2, characterized in that The content of selenium disulfide is 0.8-1.1 wt %.

4. Use of the selenium disulfide stable emulsification system according to claim 1 or 2 in preparing shampoo products.

5. A shampoo, characterized in that: The selenium disulfide stable emulsion system comprises the selenium disulfide stable emulsion system as claimed in claim 1 or 2; the selenium disulfide stable emulsion system further comprises one or more combinations of hair conditioners, silicones, fungicides, moisturizers, preservatives, chelating agents, and pH regulators.

6. The shampoo according to claim 5, characterized in that The hair conditioning agent is one or more combinations of guar hydroxypropyltrimonium chloride, polyquaternium-10, polyquaternium-7, and polyquaternium-22; the silicone is one or more combinations of emulsified silicone oil, amino silicone emulsion, and polyether-modified silicone oil; the chelating agent is one or more combinations of etidronate, disodium EDTA, and sodium hexametaphosphate; and the pH adjuster is one or more combinations of citric acid, sodium hydroxide, and sodium citrate.

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