Dosing device for preventing adhesion of inner wall of uterine cavity

Abstract

The invention discloses a drug delivery device for preventing adhesion of the inner wall of a uterine cavity, the drug delivery device is provided with a combined balloon located in the uterine cavity, the combined balloon comprises a pressure applying water bag, a drug-containing cotton mesh bag and a plastic drug exudation bag, the pressure applying water bag is sleeved with the drug-containing cotton mesh bag, and the drug exudation bag is made of a plastic material. The medicine exudation bag is provided with medicine exudation holes which are densely and evenly distributed, the medicine exudation bag is arranged outside the cotton thread mesh bag containing medicine in a sleeved mode, and the cotton thread mesh bag containing medicine is made of cotton thread meshes with different shapes of meshes. The device has the advantages of being simple in structure, convenient to use and capable of isolating the inner wall of the uterine cavity and slowly releasing medicine to the inner wall of the uterine cavity at the same time.

Description

Technical Field

[0001] The invention relates to the technical field of medical devices, in particular to a drug-delivery device for preventing adhesion of the inner wall of the uterine cavity. Background Art

[0002] Intrauterine adhesion refers to adhesion of the inner wall of the uterus, which partially or completely blocks the uterine cavity. This adhesion may be caused by surgical operations (such as artificial abortion, curettage, etc.) infection and other factors that damage the basal layer of the endometrium. The main symptoms of intrauterine adhesion include reduced menstruation, amenorrhea, cyclical abdominal pain and infertility. The adhesion part will reduce the area of ​​the endometrium in the uterine cavity, resulting in a decrease in the amount of menstrual blood discharge; severe intrauterine adhesions may cause amenorrhea. At the same time, adhesions cause poor menstrual blood flow, and the uterus contracts strongly in order to discharge menstrual blood, causing cyclical abdominal pain. Intrauterine adhesions can also easily block the uterine cavity, generally including genetics, low estrogen levels, endometrial trauma, postoperative infection, endometrial tuberculosis and other reasons. Due to damage or infection of the endometrium, the inner wall of the uterine cavity adheres together to form fibrous tissue, which in turn narrows or blocks the uterine cavity. This adhesion affects the normal function of the endometrium, including the growth, development and receptivity of the endometrium, thereby affecting the implantation of the fertilized egg and the development of the embryo. Therefore, intrauterine adhesion is an important cause of infertility. Hysteroscopic surgery is an effective method for treating intrauterine adhesion. Through hysteroscopic surgery, doctors can directly observe the intrauterine adhesion, and perform separation and removal. After surgery, it is necessary to place devices such as IUDs or balloons in the uterine cavity to prevent adhesions again. However, this balloon only plays a simple role in isolating the inner wall of the uterine cavity, and cannot administer medication to the inner wall of the uterine cavity, and cannot provide thorough treatment. Once the IUD or balloon is withdrawn, the symptoms of intrauterine adhesion may recur.

[0003] Drug therapy can be used as an auxiliary treatment for intrauterine adhesions after hysteroscopy. Tablet solid drugs or liquid drugs can also be used under the guidance of doctors. The liquid drug SVF (Stromal Vascular Fraction) "vascular matrix component" used to repair damaged tissues is an effective ingredient extracted from the patient's own adipose tissue. It is derived from the vascular matrix of adipose tissue and is obtained after the adipose tissue is filtered and centrifuged to remove mature fat cells. It contains highly plastic mesenchymal stem cells derived from adipose tissue. This cell with repair function and a cell population formed by a mixture of cytokines are easy to extract from adipose tissue, have multidirectional differentiation potential, can promote the recovery and growth of the endometrium, and can be used to repair damaged tissues. In the treatment of reproductive system diseases, SVF can be used to treat problems such as thin endometrium to improve pregnancy rates. In order to adapt to the clinical application of SVF, the development of a matching device that can administer drugs to the inner wall of the uterine cavity is of great practical significance for the treatment of diseases of the inner wall of the uterine cavity. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a drug delivery device for preventing adhesion of the uterine cavity wall, which has the characteristics of simple structure, convenient use, and can slowly release drugs to the uterine cavity wall while isolating the uterine cavity wall.

[0005] In order to solve the above technical problems, the technical solution adopted by the present invention is: a drug delivery device for preventing adhesion of the inner wall of the uterine cavity, comprising a combined balloon located in the inner cavity of the uterus, the combined balloon comprising a pressure water bag, a cotton mesh bag containing medicine and a medicine exudation bag made of plastic material, the cotton mesh bag containing medicine is sleeved on the outside of the pressure water bag, the medicine exudation bag is provided with densely and evenly distributed medicine exudation holes and is sleeved on the outside of the cotton mesh bag containing medicine, and the cotton mesh bag containing medicine is made of cotton mesh with meshes of different shapes.

[0006] In the above-mentioned drug-delivery device for preventing adhesion of the inner wall of the uterine cavity, the cotton thread net is made of a lattice-shaped cotton thread net, and a uniformly woven ball of wool capable of absorbing drugs is arranged on the lattice-shaped cotton thread net.

[0007] The above-mentioned drug delivery device for preventing adhesion of the uterine cavity wall, the lattice-shaped cotton thread net is a square lattice cotton thread net, the side length of the square is 10mm, and the wool balls that can absorb drugs are woven on each side of the square, and the diameter of the wool balls is between 3-4mm.

[0008] In the above-mentioned drug-drug administration device for preventing adhesion of the inner wall of the uterine cavity, the cotton thread net is made of a triangular grid-shaped cotton thread net.

[0009] In the above-mentioned drug-drug delivery device for preventing adhesion of the uterine cavity wall, the triangular lattice-shaped cotton thread net is an equilateral triangle lattice cotton thread net, the side length of the equilateral triangle is 10 mm, and the diameter of the cotton thread is 2-3 mm.

[0010] The beneficial technical effects of the present invention are as follows: First, the combined balloon located in the uterine cavity can slowly release drugs to repair damaged tissues onto the wall of the uterine cavity. Second, the pressure water bag maintains a certain pressure so that the drug seepage holes on the drug seepage bag are close to the inner wall of the uterine cavity, which can make the drugs fully exert their effects and avoid drug loss. Third, the wool balls on the cotton mesh bag can absorb enough drugs and continuously release drugs during the course of treatment. The present invention has a simple structure and is easy to operate during the treatment process. It has the characteristics of ensuring the treatment effect of uterine adhesions and improving the efficiency of medical operations. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a schematic diagram of the structure of the present invention;

[0012] Figure 2 It is a schematic diagram of the structure of a cotton thread net bag made of a square grid cotton thread net;

[0013] Figure 3It is a schematic diagram of the structure of a cotton thread net bag made of an equilateral triangle lattice cotton thread net;

[0014] Figure 4 It is a schematic diagram of the structure of the drug extravasation sac.

[0015] The components in the figure are numbered as follows: uterine cavity 1, drug exudation sac 2, cotton mesh bag 3, wool ball 4, pressure water bag 5, water bag filled with water 6, uterine opening 7, drug exudation sac opening 8, cotton mesh bag opening 9, pressure water bag opening 10, binding belt 11, drug exudation hole 12, square grid cotton mesh 13, equilateral triangle grid cotton mesh 14. DETAILED DESCRIPTION

[0016] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0017] like Figures 1 to 4 As shown, the present invention provides a drug-delivery device for preventing adhesion of the uterine cavity wall. During the treatment process, liquid drugs for repairing damaged tissues, crushed tablet drugs or powder drugs can be used for treatment. First, the cotton mesh bag 3 is thoroughly soaked with physiological saline; then the cotton mesh bag 3 is placed in the liquid or powder drug to allow the cotton mesh bag 3 to fully absorb the drug; finally, the cotton mesh bag 3 is dried and then mounted on the outside of the pressure water bag 5, and the drug exudation bag 2 is mounted on the outside of the cotton mesh bag to form a combined balloon.

[0018] Embodiment 1: A drug delivery device for preventing adhesion of the inner wall of the uterine cavity, comprising a combined balloon located in the uterine cavity 1, the combined balloon comprising a pressure water bag 5, a cotton mesh bag 3 containing medicine, and a medicine exudation bag 2 made of plastic material, the cotton mesh bag 3 containing medicine is sleeved on the outside of the pressure water bag 5, the medicine exudation bag 2 is provided with densely evenly distributed medicine exudation holes 12 and is sleeved on the outside of the cotton mesh bag 3 containing medicine, and the cotton mesh bag 3 containing medicine is made of cotton mesh with different shapes of meshes. The cotton mesh is made of a lattice-shaped cotton mesh, on which a uniformly woven ball of wool 4 capable of absorbing medicine is provided. The lattice-shaped cotton mesh is a square grid cotton mesh 13, the side length of the square is 10 mm, the ball of wool 4 capable of absorbing medicine is woven on each side of the square, and the diameter of the ball of wool 4 is between 3-4 mm.

[0019] Embodiment 2: A drug delivery device for preventing adhesion of the inner wall of the uterine cavity, comprising a combined balloon located in the uterine cavity 1, the combined balloon comprising a pressure water bag 5, a cotton mesh bag 3 containing medicine, and a medicine exudation bag 2 made of plastic material, the cotton mesh bag 3 containing medicine is sleeved on the outside of the pressure water bag 5, the medicine exudation bag 2 is provided with densely evenly distributed medicine exudation holes 12 and is sleeved on the outside of the cotton mesh bag 3 containing medicine, and the cotton mesh bag 3 containing medicine is made of cotton mesh with different shapes of meshes. The cotton mesh is made of a triangular grid-shaped cotton mesh. The triangular grid-shaped cotton mesh is an equilateral triangle grid cotton mesh 14, the side length of the equilateral triangle is 10 mm, and the diameter of the cotton thread is 2-3 mm.

[0020] The method of using the present invention comprises the following steps:

[0021] First, pour liquid or powdered medicine for repairing damaged tissue into a sterilized container, thoroughly soak the cotton mesh bag 3 with saline solution for disinfection, place it in the liquid or powdered medicine for repairing damaged tissue for 1-2 hours to allow the cotton mesh bag 3 to fully absorb the medicine, and then dry the cotton mesh bag 3.

[0022] Second, the pressurized water bag 5 and the drug exudation bag 2 are disinfected, clean air is filled into the pressurized water bag 5 to expand it, the mouth of the pressurized water bag 5 is sealed and a secondary disinfection is performed.

[0023] 3. The patient lies flat on the bed and completes the disinfection and related preparations for the insertion of the combined balloon.

[0024] Fourth, the cotton mesh bag 3 is sleeved on the outside of the pressure water bag 5 with the opening facing downward.

[0025] Fifth, the drug exudation capsule 2 is sheathed on the outside of the cotton mesh bag 3 to form a combined balloon. Pay attention to the positional relationship between the drug exudation capsule 2 and the cotton mesh bag 3 so that the drug exudation hole 12 of the drug exudation capsule 2 is aligned with the wool ball 4.

[0026] Sixth, the air in the pressurized water bag 5 is discharged, and the entire combined balloon is slowly placed into the patient's uterine cavity 1.

[0027] Seventh, inject physiological saline into the pressure water bag 5 to expand and stretch the inner wall of the uterus. By asking the patient, the pressure of the pressure water bag 5 is mastered to ensure that the drug exudation bag 2 contacts the inner wall of the uterine cavity. The outlet of the pressure water bag 5 is tightly sealed with a binding belt 11.

[0028] 8. After the treatment, let the patient sit on the bedpan, loosen the binding belt 11 to discharge the saline solution, and withdraw the combined balloon.

[0029] According to the disclosure and teaching of the above description, those skilled in the art to which the present invention belongs may also make appropriate changes and modifications to the above embodiments. Therefore, the present invention is not limited to the specific embodiments disclosed and described above, and some modifications and changes to the present invention should also fall within the scope of protection of the claims of the present invention. In addition, although some specific terms are used in this specification, these terms are only for the convenience of description and do not constitute any limitation to the present invention.

Claims

1. A drug delivery device for preventing adhesion of the uterine cavity wall, characterized in that: The invention comprises a combined balloon located in the uterine cavity (1), the combined balloon comprising a pressure water bag (5), a cotton mesh bag containing medicine (3) and a medicine exudation bag (2) made of plastic material, the cotton mesh bag containing medicine (3) being sheathed on the outside of the pressure water bag (5), the medicine exudation bag (2) being provided with densely and evenly distributed medicine exudation holes (12) and sheathed on the outside of the cotton mesh bag containing medicine (3), the cotton mesh bag containing medicine (3) being made of cotton mesh with meshes of different shapes.

2. A drug delivery device for preventing adhesion of the uterine cavity wall according to claim 1, characterized in that: The cotton thread net is made of a square-shaped cotton thread net, and a uniformly woven wool ball (4) capable of absorbing drugs is arranged on the square-shaped cotton thread net.

3. A drug delivery device for preventing adhesion of the uterine cavity wall according to claim 2, characterized in that: The lattice-shaped cotton thread net is a square lattice cotton thread net (13), the side length of the square is 10 mm, and a ball of yarn (4) capable of absorbing drugs is woven on each side of the square, and the diameter of the ball of yarn (4) is between 3 and 4 mm.

4. A drug delivery device for preventing adhesion of the uterine cavity wall according to claim 1, characterized in that: The cotton thread net is made of a triangular grid-shaped cotton thread net.

5. A drug delivery device for preventing adhesion of the uterine cavity wall according to claim 4, characterized in that: The triangular grid-shaped cotton thread net is an equilateral triangle grid cotton thread net (14), the side length of the equilateral triangle is 10 mm, and the diameter of the cotton thread is 2-3 mm.

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