Traditional Chinese medicine preparation for treating chronic rhinitis and chronic nasosinusitis
Through a traditional Chinese medicine preparation containing a variety of Chinese medicine ingredients, the long-term prolonged condition of patients with chronic rhinitis and chronic sinusitis is solved, and the treatment effect of effectively improving symptoms and reducing turbinate swelling is achieved.
Patent Information
- Application Number
- CN202510287964.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-12
- Publication Date
- 2025-05-16
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Patients with chronic rhinitis and chronic sinusitis are in a state of chronic heat accumulation in the lungs and spleen and gallbladder meridians for a long time, resulting in the delay of the disease and the transition from solid to deficiency, forming a syndrome of inclusion of deficiency and excess, and the condition is induced or aggravated by factors such as climate change.
It provides a traditional Chinese medicine preparation, containing coix seed, wax melon kernel, almond kernel, xanthium seed, gardenia, gentian, bupleurum, angelica, angelica, angelica, angelica, scutellaria baicalensis, scutellaria root and patchouli. It is prepared by extracting cream, mixing tableting and drying processing, and is used to treat chronic rhinitis and chronic sinusitis.
This traditional Chinese medicine preparation effectively improves nasal congestion, headache or dizziness, and diarrhea in the middle and lower abdomen, removes heat from the upper abdomen, aromatic opens orifices, promotes the upward movement of the medicine, and leads to dampness and turbidity, which can effectively improve symptoms such as nasal congestion, headache or dizziness, and reduces olfactory sense, significantly alleviates swelling of the nasal turbinate and improves the treatment effect of the patient.
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Figure CN120000748A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of Chinese medicine preparations, and in particular to a Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis. Background Art
[0002] Chronic rhinitis and chronic sinusitis belong to diseases of the lung, spleen, and gallbladder in traditional Chinese medicine. The course of the disease is often long. The onset of the disease often begins with external invasion of wind evil, accumulation of heat in the lung meridian, or combined with gallbladder heat and spleen dampness, wind, dampness, and heat evil stagnation in the nasal passages, steaming and burning body fluids, and turbid mucus flowing down; improper treatment, or insufficient vital energy, the disease is prolonged and not cured, and it can turn from real to virtual, forming a mixed syndrome of virtual and real. At the same time, due to the prolonged and uncured disease, the disease enters the collaterals for a long time, and blood stasis appears in the nasal cavity, manifesting as stubborn nasal congestion. It can be seen that the long-term state of damp-heat stagnation has a significant impact on this disease. Patients are in a state of heat accumulation in the lungs and spleen and heat stagnation in the gallbladder meridian for a long time, and even sudden climate changes, such as daytime temperature changes, seasonal changes, and solar terms, may induce or aggravate the disease.
[0003] With the improvement of people's living standards and the increase of life and study pressure, the problem of internal heat accumulation in children and adults is becoming more and more common and more serious, and the incidence of related diseases is also increasing year by year. In the diagnosis and treatment of related diseases, people tend to focus more on the treatment of superficial symptoms, while the diagnosis, treatment and care of other internal organs are insufficient. Ignoring the treatment of spleen and stomach problems has a particularly significant negative impact on the treatment of the disease in the middle and late stages. For this reason, we propose a Chinese medicine preparation for the treatment of chronic rhinitis and chronic sinusitis. Summary of the invention
[0004] The purpose of the present invention is to solve the problems mentioned in the above background technology. The present invention provides a Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis.
[0005] In order to achieve the above-mentioned purpose, the present invention specifically adopts the following technical solutions:
[0006] A traditional Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis, the traditional Chinese medicine preparation being composed of the following parts: 25-35 parts of coix seeds, 20-28 parts of wax gourd seeds, 7-11 parts of almonds, 7-11 parts of xanthium fruits, 7-11 parts of gardenias, 7-11 parts of gentiana, 7-11 parts of bupleurum, 7-11 parts of angelica dahurica, 7-11 parts of siler, 7-11 parts of scutellaria, 22-26 parts of imperata roots, and 7-11 parts of patchouli.
[0007] Furthermore, the Chinese medicine preparation is composed of the following parts: 25 parts of coix seed, 24 parts of wax gourd seed, 9 parts of almond, 9 parts of Xanthium sibiricum, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica, and 9 parts of Patchouli.
[0008] Furthermore, the Chinese medicine preparation is composed of the following parts: 30 parts of coix seed, 24 parts of wax gourd seed, 9 parts of almond, 9 parts of Xanthium sibiricum, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica, and 9 parts of Patchouli.
[0009] Furthermore, the Chinese medicine preparation is composed of 35 parts of coix seed, 28 parts of wax gourd seed, 11 parts of almond, 11 parts of Xanthium sibiricum, 11 parts of Gardenia jasminoides, 11 parts of gentian, 11 parts of Bupleurum chinense, 11 parts of Angelica dahurica, 11 parts of Saposhnikovia divaricata, 11 parts of Scutellaria baicalensis, 28 parts of Imperata cylindrica, and 11 parts of Patchouli.
[0010] Furthermore, the preparation method of the Chinese medicine preparation comprises the following steps:
[0011] S1. Raw material preparation, selecting raw materials according to the proportion;
[0012] S2, preparation of medicinal materials, step-by-step processing for different raw materials;
[0013] S3, extract decoction, mixing the prepared medicinal materials with water in a certain proportion, concentrating the concentrated juice, filtering, precipitating, clarifying and other treatments to remove impurities, and obtaining a clear extract;
[0014] S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press;
[0015] S5, drying process, placing the prepared tablets in an oven to evaporate the water in the tablets and achieve drying;
[0016] S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
[0017] Furthermore, the raw material preparation in S1 includes the following steps:
[0018] S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof;
[0019] S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking;
[0020] S13, draining, taking out the soaked medicinal materials and draining them.
[0021] Furthermore, the preparation of the S2 Chinese medicinal materials includes: grinding, cutting, stir-frying, roasting with wine and proportioning, wherein coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
[0022] Furthermore, the extract paste in S3 is concentrated using a high-temperature concentrator, the heating temperature is 200-220° C., and the concentration time is 1-2 hours.
[0023] Furthermore, the drying temperature in the drying process in S5 is 80-100° C., and the drying time is 2-4 hours.
[0024] Furthermore, the drying process in S5 also includes: quality inspection, testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.
[0025] The beneficial effects of the present invention are as follows:
[0026] 1. The present invention comprises gentian, bupleurum, wine-fried scutellaria and stir-fried gardenia, which are used to treat the middle and upper parts of the body. Gentian and bupleurum are used to clear the dampness and heat in the middle and lower parts of the body, and stir-fried gardenia, wine-fried scutellaria and Imperata root are used to remove the heat in the upper part of the body; stir-fried Xanthium sibiricum, Angelica dahurica and Patchouli have strong pungent and dispersing power and aromatic orifices, and are supplemented with saposhnikovia to promote the upward movement of drugs; coix seeds and wax gourd seeds are used to guide and eliminate dampness and turbidity.
[0027] 2. The disease of the present invention is lingering, and long-term illness may cause blood stasis, so peach kernel is matched alone to promote blood circulation and remove blood stasis. All medicines are used together to have the effects of ascending clear and descending turbidity, clearing away heat and removing dampness. BRIEF DESCRIPTION OF THE DRAWINGS
[0028] Figure 1 It is a work flow chart of the present invention;
[0029] Figure 2 It is a work flow chart of raw material preparation in the present invention;
[0030] Figure 3 It is a working framework diagram of the preparation of Chinese medicinal materials of the present invention. DETAILED DESCRIPTION
[0031] To make the purpose, technical solution and advantages of the embodiments of the present invention more clear, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention.
[0032] See also Figure 1 - Figure 3The present invention provides a traditional Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis. The traditional Chinese medicine preparation is composed of the following parts: 25-35 parts of coix seeds, 20-28 parts of wax gourd seeds, 7-11 parts of almonds, 7-11 parts of Xanthium sibiricum seeds, 7-11 parts of Gardenia jasminoides, 7-11 parts of gentiana, 7-11 parts of bupleurum chinense, 7-11 parts of angelica dahurica, 7-11 parts of siler, 7-11 parts of scutellaria baicalensis, 22-26 parts of Imperata cylindrica roots, and 7-11 parts of patchouli.
[0033] Coix seeds, according to the 2020 edition of the Chinese Pharmacopoeia: Nature and flavor and meridians: sweet, light, and cool. It enters the spleen, stomach, and lung meridians; Functions and indications: diuresis and dampness, spleen-strengthening and diarrhea-stopping, numbness-eliminating, pus-discharging, detoxification and stagnation-dispersing;
[0034] Winter melon seeds, according to the 2020 edition of the Chinese Pharmacopoeia: Nature and flavor and meridians: sweet, cool. It belongs to the foot jueyin meridian; Functions and indications: moistening the lungs, resolving phlegm, eliminating carbuncle, and promoting diuresis;
[0035] Almonds, according to the 2020 edition of the Chinese Pharmacopoeia: Nature and flavor and meridians: bitter, sweet, neutral. It enters the heart, liver, and large intestine meridians; Functions and indications: activating blood circulation and removing blood stasis, moistening the intestines and relieving constipation, relieving cough and relieving asthma;
[0036] Xanthium sibiricum, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: pungent, bitter, warm; toxic. Enters the lung meridian; Functions and indications: dispel wind and cold, open the nasal passages, and eliminate rheumatism;
[0037] Gardenia, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: bitter, cold. It enters the heart, lung, and triple burner meridians; Functions and indications: purging fire and relieving restlessness, clearing heat and removing dampness, cooling blood and detoxifying; external use to reduce swelling and relieve pain;
[0038] Gentiana scabra, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: bitter, cold. Enters the lung and liver meridians; Functions and indications: clearing heat and resolving phlegm, relieving cough and asthma, detoxifying and removing dampness, cooling blood and stopping bleeding;
[0039] Bupleurum chinense, according to the 2020 edition of the Chinese Pharmacopoeia: Nature and flavor and meridians: sweet, slightly cold. Enters the liver and stomach meridians; Functions and indications: clears away heat from deficiency and eliminates malnutrition heat;
[0040] Angelica dahurica, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: pungent, warm. Enters the stomach, large intestine, and lung meridians; Functions and indications: dispels cold, dispels wind and relieves pain, clears the nasal passages, dries dampness and stops leukorrhea, reduces swelling and discharges pus;
[0041] Fangfeng, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: pungent, sweet, slightly warm. It enters the bladder, liver, and spleen meridians; Functions and indications: dispel wind and relieve exterior symptoms, overcome dampness and relieve pain, and stop spasms;
[0042] Scutellaria baicalensis, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: bitter, cold. Enter the lung, gallbladder, spleen, large intestine, and small intestine meridians; Functions and indications: clearing away heat and dampness, purging fire and detoxifying, stopping bleeding, and calming the fetus;
[0043] Imperata root, the 2020 edition of the Chinese Pharmacopoeia records: Nature and flavor and meridians: sweet, cold. Enter the lung, stomach, and bladder meridians; Functions and indications: cooling blood and stopping bleeding, clearing heat and promoting diuresis;
[0044] Patchouli, as recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature and flavor and meridians: pungent, slightly warm. Enters the spleen, stomach, and lung meridians; Functions and indications: aromatic and turbid, harmonizes the stomach and stops vomiting, and releases heat.
[0045] In this embodiment, preferably, the preparation method of the traditional Chinese medicine preparation comprises the following steps:
[0046] S1. Raw material preparation, selecting raw materials according to the proportion;
[0047] S2, preparation of medicinal materials, step-by-step processing for different raw materials;
[0048] S3, extract decoction, mixing the prepared medicinal materials with water in a certain proportion, concentrating the concentrated juice, filtering, precipitating, clarifying and other treatments to remove impurities, and obtaining a clear extract;
[0049] S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press;
[0050] S5, drying process, placing the prepared tablets in an oven to evaporate the water in the tablets and achieve drying;
[0051] S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
[0052] In this embodiment, preferably, the raw material preparation in S1 includes the following steps:
[0053] S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof;
[0054] S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking;
[0055] S13, draining, taking out the soaked medicinal materials and draining them.
[0056] In this embodiment, preferably, the preparation of S2 Chinese medicinal materials includes: grinding, cutting, stir-frying, roasting with wine and proportioning, wherein coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
[0057] In this embodiment, preferably, the extract in S3 is concentrated using a high-temperature concentrator, the heating temperature is 200-220° C., and the concentration time is 1-2 hours.
[0058] In this embodiment, preferably, the drying temperature in the drying process in S5 is 80-1000° C., and the drying time is 2-4 hours.
[0059] In this embodiment, preferably, the drying process in S5 further includes: quality inspection, testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.
[0060] Example 1
[0061] The preparation method of the Chinese medicine preparation comprises the following steps:
[0062] S1. Raw material preparation, selecting raw materials according to the proportion: 25 parts of coix seeds, 24 parts of wax gourd seeds, 9 parts of almond seeds, 9 parts of Xanthium sibiricum seeds, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica roots, and 9 parts of Patchouli; comprising the following steps:
[0063] S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof;
[0064] S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking;
[0065] S13, draining, taking out the soaked medicinal materials and draining them.
[0066] S2. Preparation of medicinal materials. Different raw materials are processed step by step, including grinding, cutting, stir-frying, roasting with wine and proportioning. Among them, coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
[0067] Gentiana scabra, Bupleurum chinense, wine-roasted Scutellaria baicalensis, and stir-fried Gardenia jasminoides are used to treat the middle and upper Jiao. Gentiana scabra and Bupleurum chinense are used to clear the damp-heat in the middle and lower Jiao, while stir-fried Gardenia jasminoides, wine-roasted Scutellaria baicalensis, and Imperata cylindrica are used to remove the heat in the upper Jiao. Stir-fried Xanthium sibiricum, Angelica dahurica, and Patchouli have strong pungent and dispersing power and aromatic properties to open the orifices, assisted by Saposhnikovia divaricata to promote movement of the herbs upward. Coix seeds and wax gourd seeds can eliminate dampness and turbidity. The disease is lingering and may cause blood stasis if it is treated for a long time, so peach kernel is used alone to promote blood circulation and remove blood stasis. All the herbs are used together to achieve the effects of clearing the dampness and descending the turbidity, clearing heat and removing dampness.
[0068] S3, extract paste, the prepared medicinal materials and water are mixed in a certain proportion, concentrated into concentrated juice, the concentrated juice is filtered, precipitated, clarified and other treatments to remove impurities to obtain a clear extract; a high-temperature concentrator is used for concentration, the heating temperature is 200 ° C, and the concentration time is 1 hour.
[0069] S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press;
[0070] S5, drying process, putting the prepared tablets into an oven to evaporate the water in the tablets and achieve drying; the processing drying temperature is 80°C and the drying time is 2 hours. It also includes: quality inspection, testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.
[0071] S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
[0072] Example 2
[0073] The preparation method of the Chinese medicine preparation comprises the following steps:
[0074] S1. Raw material preparation, selecting raw materials according to the proportion: 30 parts of coix seeds, 24 parts of wax gourd seeds, 9 parts of almond seeds, 9 parts of Xanthium sibiricum seeds, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica roots, and 9 parts of Patchouli; comprising the following steps:
[0075] S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof;
[0076] S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking;
[0077] S13, draining, taking out the soaked medicinal materials and draining them.
[0078] S2. Preparation of medicinal materials. Different raw materials are processed step by step, including grinding, cutting, stir-frying, roasting with wine and proportioning. Among them, coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
[0079] Gentiana scabra, Bupleurum chinense, wine-roasted Scutellaria baicalensis, and stir-fried Gardenia jasminoides are used to treat the middle and upper Jiao. Gentiana scabra and Bupleurum chinense are used to clear the damp-heat in the middle and lower Jiao, while stir-fried Gardenia jasminoides, wine-roasted Scutellaria baicalensis, and Imperata cylindrica are used to remove the heat in the upper Jiao. Stir-fried Xanthium sibiricum, Angelica dahurica, and Patchouli have strong pungent and dispersing power and aromatic properties to open the orifices, assisted by Saposhnikovia divaricata to promote movement of the herbs upward. Coix seeds and wax gourd seeds can eliminate dampness and turbidity. The disease is lingering and may cause blood stasis if it is treated for a long time, so peach kernel is used alone to promote blood circulation and remove blood stasis. All the herbs are used together to achieve the effects of clearing the dampness and descending the turbidity, clearing heat and removing dampness.
[0080] S3, extract paste, the prepared medicinal materials and water are mixed in a certain proportion, concentrated into concentrated juice, the concentrated juice is filtered, precipitated, clarified and other treatments to remove impurities to obtain a clear extract; a high-temperature concentrator is used for concentration, the heating temperature is 210 ° C, and the concentration time is 1.5 hours.
[0081] S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press;
[0082] S5, drying process, putting the prepared tablets into an oven to evaporate the water in the tablets and achieve drying; the processing drying temperature is 90°C and the drying time is 3 hours. It also includes: quality inspection, testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.
[0083] S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
[0084] Example 3
[0085] The preparation method of the Chinese medicine preparation comprises the following steps:
[0086] S1. Raw material preparation, selecting raw materials according to the proportion: 35 parts of coix seeds, 28 parts of wax gourd seeds, 11 parts of almond seeds, 11 parts of Xanthium sibiricum seeds, 11 parts of Gardenia jasminoides, 11 parts of Gentiana scabra, 11 parts of Bupleurum chinense, 11 parts of Angelica dahurica, 11 parts of Saposhnikovia divaricata, 11 parts of Scutellaria baicalensis, 28 parts of Imperata cylindrica roots, and 11 parts of Patchouli; comprising the following steps:
[0087] S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof;
[0088] S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking;
[0089] S13, draining, taking out the soaked medicinal materials and draining them.
[0090] S2. Preparation of medicinal materials. Different raw materials are processed step by step, including grinding, cutting, stir-frying, roasting with wine and proportioning. Among them, coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
[0091] Gentiana scabra, Bupleurum chinense, wine-roasted Scutellaria baicalensis, and stir-fried Gardenia jasminoides are used to treat the middle and upper Jiao. Gentiana scabra and Bupleurum chinense are used to clear the damp-heat in the middle and lower Jiao, while stir-fried Gardenia jasminoides, wine-roasted Scutellaria baicalensis, and Imperata cylindrica are used to remove the heat in the upper Jiao. Stir-fried Xanthium sibiricum, Angelica dahurica, and Patchouli have strong pungent and dispersing power and aromatic properties to open the orifices, assisted by Saposhnikovia divaricata to promote movement of the herbs upward. Coix seeds and wax gourd seeds can eliminate dampness and turbidity. The disease is lingering and may cause blood stasis if it is treated for a long time, so peach kernel is used alone to promote blood circulation and remove blood stasis. All the herbs are used together to achieve the effects of clearing the dampness and descending the turbidity, clearing heat and removing dampness.
[0092] S3, extract paste, the prepared medicinal materials and water are mixed in a certain proportion, and concentrated into concentrated juice, and the concentrated juice is filtered, precipitated, clarified and other treatments to remove impurities to obtain a clear extract; a high-temperature concentrator is used for concentration, and the heating temperature is 220°C and the concentration time is 2 hours.
[0093] S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press;
[0094] S5, drying process, putting the prepared tablets into an oven to evaporate the water in the tablets and achieve drying; the processing drying temperature is 100°C and the drying time is 4 hours. It also includes: quality inspection, testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.
[0095] S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
[0096] test
[0097] 1. Designate experimental and control groups
[0098] 80 patients diagnosed with chronic rhinosinusitis were selected and randomly divided into experimental group I, experimental group II, experimental group III and control group, with 20 cases in each group. Among them, the male-female ratio of experimental group I, experimental group II, experimental group III and control group was 1:1, and there was no statistical difference in age, gender, etc. among the patients in each group, which was comparable.
[0099] 2. Treatment
[0100] The experimental group I was treated with the Chinese medicine preparation of Example 1 of the present invention, once in the morning and evening, for four consecutive courses, each course lasting one week;
[0101] The experimental group II was treated with the Chinese medicine preparation of Example 2 of the present invention, once in the morning and evening, for four consecutive courses, each course lasting one week;
[0102] The experimental group III was treated with the Chinese medicine preparation of Example 3 of the present invention, once in the morning and evening, for four consecutive courses, each course lasting one week;
[0103] The control group received no treatment.
[0104] 3. Effect
[0105] Observe the therapeutic effects, incidence of adverse reactions and evaluation of therapeutic effects of patients in test group Ⅰ, test group Ⅱ, test group Ⅲ and control group:
[0106] The therapeutic index N = [(score before treatment - score after treatment) / score before treatment)] × 100%.
[0107] 1) Effective: After treatment, the symptoms of runny nose (nasal secretions), nasal congestion, headache or dizziness, and hyposmia are significantly improved, and the swelling of the nasal concha is significantly reduced, with an efficacy index of 70% ≤ N < 90%;
[0108] 2) Significant effect: after treatment, nasal discharge (nasal secretions), nasal congestion, headache or dizziness, and decreased sense of smell are not obvious, and there is no obvious swelling of the nasal concha, and the efficacy index N is ≥ 90%;
[0109] 3) Ineffective: After treatment, there was no significant change in nasal discharge (nasal secretions), nasal congestion, headache or dizziness, hyposmia and nasal concha swelling, and the efficacy index N was less than 30%.
[0110] 4. Results
[0111] Table 1
[0112]
[0113] 5. Conclusion
[0114] It can be seen from Table 1 that Example 2 is the best solution.
[0115] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.
Claims
1. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 25-35 parts of coix seeds, 20-28 parts of wax gourd seeds, 7-11 parts of almond seeds, 7-11 parts of Xanthium sibiricum seeds, 7-11 parts of Gardenia jasminoides, 7-11 parts of Gentiana scabra, 7-11 parts of Bupleurum chinense, 7-11 parts of Angelica dahurica, 7-11 parts of Saposhnikovia divaricata, 7-11 parts of Scutellaria baicalensis, 22-26 parts of Imperata cylindrica roots, and 7-11 parts of Patchouli.
2. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 25 parts of coix seeds, 24 parts of wax gourd seeds, 9 parts of almond seeds, 9 parts of Xanthium sibiricum fruits, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica roots, and 9 parts of Patchouli.
3. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 30 parts of coix seeds, 24 parts of wax gourd seeds, 9 parts of almond seeds, 9 parts of Xanthium sibiricum fruits, 9 parts of Gardenia jasminoides, 9 parts of Gentiana scabra, 9 parts of Bupleurum chinense, 9 parts of Angelica dahurica, 9 parts of Saposhnikovia divaricata, 9 parts of Scutellaria baicalensis, 24 parts of Imperata cylindrica roots, and 9 parts of Patchouli.
4. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 35 parts of coix seeds, 28 parts of wax gourd seeds, 11 parts of almond seeds, 11 parts of Xanthium sibiricum fruits, 11 parts of Gardenia jasminoides, 11 parts of Gentiana scabra, 11 parts of Bupleurum chinense, 11 parts of Angelica dahurica, 11 parts of Saposhnikovia divaricata, 11 parts of Scutellaria baicalensis, 28 parts of Imperata cylindrica roots, and 11 parts of Patchouli.
5. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 1, characterized in that: The preparation method of the Chinese medicine preparation comprises the following steps: S1. Raw material preparation, selecting raw materials according to the proportion; S2, preparation of medicinal materials, step-by-step processing for different raw materials; S3, extract decoction, mixing the prepared medicinal materials with water in a certain proportion, concentrating the concentrated juice, filtering, precipitating, clarifying and other treatments to remove impurities, and obtaining a clear extract; S4, mixing and tableting, the extract is pressed into solid tablets by a tablet press; S5, drying process, placing the prepared tablets in an oven to evaporate the water in the tablets and achieve drying; S6. Packaging and storage: pack the tablets into bags or bottles according to specifications and packaging requirements, and store the packaged tablets in a cool, dry, ventilated, odor-free warehouse to avoid the effects of moisture, sunlight, odor, etc. on the drugs.
6. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 5, characterized in that: The raw material preparation in S1 includes the following steps: S11, cleaning, placing the prepared medicinal materials in a cleaning machine for cleaning to remove adhesions on the surface thereof; S12, soaking, placing the cleaned medicinal materials in a soaking tank for soaking; S13, draining, taking out the soaked medicinal materials and draining them.
7. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 5, characterized in that: The preparation of the S2 Chinese medicinal materials includes: grinding, cutting, stir-frying, roasting with wine and proportioning, wherein coix seed, wax gourd seed, almond seed, angelica dahurica, saposhnikovia divaricata and scutellaria baicalensis are ground; gentian, bupleurum chinense, Imperata cylindrica and patchouli are cut; Xanthium sibiricum and Gardenia jasminoides are stir-fried; Scutellaria baicalensis is roasted with wine; and each medicinal material is prepared according to the proportion.
8. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 5, characterized in that: The extract in S3 is concentrated by a high-temperature concentrator at a heating temperature of 200 to 220° C. for 1 to 2 hours.
9. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 5, characterized in that: The drying temperature in the drying process in S5 is 80 to 100° C., and the drying time is 2 to 4 hours.
10. A Chinese medicine preparation for treating chronic rhinitis and chronic sinusitis according to claim 5, characterized in that: The drying process in S5 also includes quality inspection, which includes testing the appearance, size, hardness, solubility, content and other indicators of the dried tablets to ensure the quality of the medicine.