A method for preparing chiral cadmium selenide quantum dots and their application in retinal degeneration
By preparing optimized chiral cadmium selenide quantum dots, the problems of complex preparation and high cost in existing technologies have been solved, enabling effective treatment of retinal degenerative diseases, especially showing significant protective effects against retinal damage caused by high intraocular pressure and oxidative stress.
Patent Information
- Application Number
- CN202510270747.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-07
- Publication Date
- 2026-03-10
- Estimated Expiration
- 2045-03-07
AI Technical Summary
Existing technologies for preparing chiral quantum dots are complex and costly, and their biocompatibility and toxicity issues have not been effectively resolved, with limited efficacy in the treatment of retinal degeneration.
A sodium selenate solution was prepared using selenium powder and sodium hydroxide. A Cd-D-Cys complex was formed by combining cadmium chloride and the chiral ligand D-cysteine. Cadmium selenide quantum dots were formed by microwave heating and then purified by centrifugation. The preparation parameters were optimized to obtain highly efficient chiral cadmium selenide quantum dots.
Chiral cadmium selenide quantum dots exhibit good biocompatibility and have a significant protective effect against retinal damage caused by high intraocular pressure or oxidative stress, improving the survival rate of retinal ganglion cells and alleviating pathological changes.