Application of firming and stability-maintaining periocular conditioning composition in skin care products

Abstract

The invention discloses application of a firming and stability-maintaining periocular conditioning composition in skin care products, and the firming and stability-maintaining periocular conditioning composition is used for improving fragrance and promoting absorption. The composition prepared by compounding the specific components including the barrier repairing agent, the emollient, the hydroxyl compound, the surfactant, the thickener and the chelating agent in proportion has good heat resistance and cold resistance, is good in stability, can be stored for a long time, can promote regeneration of eye skin cells, keeps and regulates skin moisture, recovers skin elasticity, and has a good application prospect. The eye cream has the effects of whitening skin, delaying body aging, resisting oxidation, whitening skin, resisting inflammation and bacteria, inhibiting formation and precipitation of melanin in skin, effectively removing dark circles, minimizing pores and tightening eye skin. Besides, when the composition is used for an eye skin care product, the composition is good in fragrance, fast in absorption and smooth in smearing, the mud rubbing phenomenon is avoided, the situation that fine lines of eyes are further deepened due to the fact that the force is difficult to control in the smearing process is avoided, and the multiple requirements for wrinkle resistance, dark circle removal and the like of different skin types can be met.

Description

Technical Field

[0001] The present invention relates to the field of preparation of eye creams, A61Q19 / 08, and particularly to the application of a firming and stabilizing eye contour conditioning composition in skin care products. Background Art

[0002] The eye skin of a person is different from the skin of other parts of the face in that it is more fragile, and due to the high-frequency movement of the eyes, it is more vulnerable to the influence of the external environment, and general skin care products cannot be commonly used for eye skin care. The research and development of eye creams has solved the problems of dark circles and fine lines for people to a certain extent, and an important point that cannot be ignored is the fragrance of eye creams. The fragrance in skin care products can not only cover up the bad smell of the chemical raw materials used and enhance the high-class sense of the product, but more importantly, it can invisibly improve the mood of users and increase the sense of pleasure. At the same time, a suitable fragrance can bring enhanced psychological suggestions to users and make a deep impression on consumers. At present, most of the fragrances used in the market are selected to improve the fragrance.

[0003] Chinese Patent Application CN102379834A discloses an aromatic plant extract for comprehensively conditioning eye skin and its eye care product. The aromatic plant extract includes an efficacy essential oil and an efficacy floral water. When used in an eye care product, it can not only comprehensively condition problems such as dark circles and fine lines in the eyes, but also replace the fragrance to improve the product fragrance and endow it with a natural plant aroma. However, the essential oil is expensive and the plant fragrance is strong and cannot be generally accepted. Chinese Patent Application CN106473980A discloses an application of a pure natural blood-activating and anti-aging skin care composition in cosmetics, which selects extracts of 14 plants and Chinese herbal medicines such as maritime pine bark / bud extract and acanthopanax senticosus extract, can effectively scavenge free radicals, and has the effects of activating blood circulation, anti-aging, whitening and moisturizing. The added borneol can increase the fragrance of the skin care product, but a large amount of plant extracts will cause its absorption efficiency to deteriorate.

[0004] Based on this, providing a composition with long-lasting fragrance, good ductility and remarkable efficacy is an urgent technical problem to be solved by those skilled in the art. Summary of the Invention

[0005] The present invention provides an application of a firming and stabilizing eye contour conditioning composition in skin care products. Through specific preparation methods and the action of specific barrier repair agents and emollients, it can not only care for the eye skin, but also has a long-lasting fragrance and suitable ductility, with strong formula compatibility and good practicability.

[0006] The first aspect of the present invention provides an application of a firming and stabilizing eye contour conditioning composition in skin care products. The firming and stabilizing eye contour conditioning composition includes at least a barrier repair agent and an emollient; it is used to improve the fragrance and absorption rate of skin care products.

[0007] In some preferred embodiments, the method for preparing the firming and stabilizing eye care composition comprises the following steps:

[0008] (1) Add a thickening agent to a preparation pot filled with water, start bottom homogenization until evenly dispersed without white lumps, and then start heating under stirring to obtain mixture A;

[0009] (2) Add a surfactant, an emollient, and a hydroxy compound to another stirring pot, heat and stir to mix to obtain mixture B;

[0010] (3) Mix mixture A and mixture B, then perform homogenization stirring and internal and external stirring, and cool down to 30 - 50 °C to obtain mixture C;

[0011] (4) Add a barrier repair agent to mixture C, perform homogenization stirring and sampling inspection, and after passing the inspection, filter through a 200 - mesh filter cloth and discharge to obtain the product.

[0012] In some preferred embodiments, in step (1), the frequency of homogenization is 10 - 30 Hz, the time is 5 - 40 min, the frequency of stirring is 10 - 50 Hz, and the heating temperature is 60 - 95 °C.

[0013] More preferably, in step (1), the frequency of homogenization is 15 - 25 Hz, the time is 10 - 25 min, the frequency of stirring is 20 - 30 Hz, and the heating temperature is 70 - 90 °C;

[0014] Most preferably, in step (1), the frequency of homogenization is 25 Hz, the time is 15 min, the frequency of stirring is 25 Hz, and the heating temperature is 85 °C.

[0015] In some preferred embodiments, in step (2), the heating temperature is 75 - 100 °C; preferably, in step (2), the heating temperature is 85 °C.

[0016] In some preferred embodiments, in step (3), the frequency of homogenization stirring is 25 - 35 Hz, the frequency of internal and external stirring is 15 - 25 Hz, and the time of homogenization stirring is 5 - 8 min; preferably, in step (3), the frequency of homogenization stirring is 30 Hz, the frequency of internal and external stirring is 25 Hz, and the time of homogenization stirring is 6 min.

[0017] In some preferred embodiments, in step (4), the time of homogenization stirring is 8 - 10 min; preferably, in step (4), the time of homogenization stirring is 9 min.

[0018] In some preferred embodiments, the weight ratio of the barrier repair agent, emollient, hydroxy compound, thickener, and surfactant is (8-15):(5-13):(3-8.5):(0.2-0.6):(3-6.5); preferably 13:10:7:0.4:5.0.

[0019] In some preferred embodiments, the barrier repair agent is selected from one or more of sodium hyaluronate, trehalose, betaine, Tremella Fuciformis fruit body extract, dipalmitoyl hydroxyproline, hydrogenated lecithin, Centella Asiltica extract, Acmella Oleracea extract mixture, dipotassium glycyrrhizinate, hydroxypinacolone retinoate mixture, panthenol, Fraxinus Excelisior bark extract mixture, Panax Ginseng root extract, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, palmitoyl tetrapeptide-3 mixture, 1,3-propanediol-water-Acmella Oleracea extract, Spilanthes Acella flower extract, caffeine, panthenol, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 mixture.

[0020] Preferably, the barrier repair agent is sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Acmella Oleracea extract mixture, hydroxypinacolone retinoate mixture, panthenol, Fraxinus Excelisior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Acmella Oleracea extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid mixture.

[0021] In some preferred embodiments, the Acmella Oleracea extract mixture is a mixture of triglyceride caprylate / caprate and Acmella Oleracea extract.

[0022] In some preferred embodiments, the hydroxypinacolone retinoate mixture is a mixture of isosorbide dimethyl ether and hydroxypinacolone retinoate.

[0023] In some preferred embodiments, the Fraxinus Excelisior bark extract mixture is a mixture of butanediol, water, niacinamide, Fraxinus Excelisior bark extract, and silanetriol.

[0024] In some preferred embodiments, the dipeptide-2 and palmitoyl tetrapeptide-7 mixture is a mixture of water, glycerol, hesperidin methyl chalcone, steareth, 20-dipeptide-2 and palmitoyl tetrapeptide-7.

[0025] In some preferred embodiments, the palmitoyl tetrapeptide-3 mixture is a mixture of dipeptide-2, hesperidin methyl chalcone, and palmitoyl tetrapeptide-3.

[0026] In some preferred embodiments, the coffee extract mixture is a mixture of Coffea Arabica extract and cyclodextrin.

[0027] In some preferred embodiments, the 3-O-ethyl ascorbic acid mixture is a mixture of water-glycerol-soybean lecithin, 1,3-propanediol, 1,2-hexanediol, 3-O-ethyl ascorbic acid, acetyl hexapeptide-8, cholesterol, octanoyl hydroxamic acid, acryloyldimethyltauramide / VP copolymer, and Prunus persica flower extract.

[0028] In some preferred embodiments, the mass ratio of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Centaurea cyanus extract mixture, hydroxypinacolone retinoate mixture, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Centaurea cyanus extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, and 3-O-ethyl ascorbic acid mixture is (0.1-0.7):(0.2-0.9):(0.3-0.7):(0.1-2.0):(0.05-0.3):(0.5-4):(0.05-0.3):(0.3-0.8):(0.5-5.0):(0.2-2.5):(1.0-5.0):(0.1-2.0):(0.1-2.0):(0.005-0.2):(0.005-0.3):(0.1-2.0).

[0029] Preferably, the mass ratio of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Centaurea cyanus extract mixture, hydroxypinacolone retinoate mixture, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Centaurea cyanus extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, and 3-O-ethyl ascorbic acid mixture is 0.5:0.5:0.5:1:0.1:2.0:0.1:0.5:3.0:1.0:2.0:0.5:0.35:0.01:0.01:0.5.

[0030] The molecular weights of various active ingredients contained in plant extracts are small, easy to absorb, not likely to deposit in the body, and have obvious usage effects with no side effects after long-term use. The combined use of Ganoderma lucidum extract, Gynostemma pentaphyllum extract and a mixture of other plant extracts in this application helps to promote the metabolism of eye skin cells, achieving functions such as moisturizing, delaying the aging of the body, whitening and anti-inflammatory, astringing pores, enhancing skin defense and immune functions. However, the natural fragrances in these plant extracts may reduce the usage experience after being mixed, and their dissolution stability is relatively poor. The applicant unexpectedly found that adding Centaurea cyanus extract, especially a mixture of Centaurea cyanus extracts, to the above system can significantly improve the fragrance of the obtained composition. In addition, it synergistically acts with the hydroxypinacolone retinoate mixture in the system and other components in the system, further improving the fragrance of the composition, making it acceptable to the general public. At the same time, it significantly improves the dispersibility, compatibility of each component in the system and the activity of the nutrient molecules of the plant extracts, increases the stability of the system, improves the temperature resistance of the prepared composition, and increases the absorption efficiency and absorption amount of the composition, effectively enhancing the effects of the composition on tightening eye skin, anti-wrinkle and removing dark circles under the eyes. It is applicable to various skin types such as oily skin, dry skin, pigmented skin, wrinkled skin, etc., especially suitable for people with serious eye pigment deposition, fine eye lines and many wrinkles caused by excessive eye use.

[0031] In some preferred embodiments, the emollient is selected from one or more of octyldodecanol, polydimethylsiloxane, bis-PEG-18 methyl ether dimethylsilane, sorbitol, phytosterol oleate, collagen, squalane, tocopheryl acetate, cyclopentasiloxane; preferably, the emollient is octyldodecanol, phytosterol oleate, squalane, tocopheryl acetate and cyclopentasiloxane.

[0032] In some preferred embodiments, the squalane is phytosqualane; more preferably, the source of the phytosqualane is olive oil.

[0033] In some preferred embodiments, the mass ratio of octyldodecanol, phytosterol oleate, squalane, tocopheryl acetate and cyclopentasiloxane is (1.0 - 5.0):(0.05 - 3.0):(0.05 - 4.0):(0.01 - 0.5):(0.5 - 4.0); preferably, the mass ratio of octyldodecanol, phytosterol oleate, squalane, tocopheryl acetate and cyclopentasiloxane is 3.0:2.0:3.0:0.1:2.0.

[0034] In some preferred embodiments, the hydroxy compound is selected from one or more of propylene glycol, butylene glycol, glycerol, propylene glycol, glycerol polyether-26, octyldecanol, and octyldecanol mixture; preferably, the hydroxy compound is a mixture of glycerol, glycerol polyether-26, and octyldecanol.

[0035] In some preferred embodiments, the octyldecanol mixture is a mixture of isopentyl glycol, octyldecanol, 1,2-hexanediol, p-hydroxyacetophenone, and dipropylene glycol.

[0036] In some preferred embodiments, the mass ratio of the glycerol, glycerol polyether-26, and octyldecanol mixture is (1.0 - 4.5):(2.0 - 5.0):(0.5 - 2.0); preferably, the mass ratio of the glycerol, glycerol polyether-26, and octyldecanol mixture is 3.0:3.0:1.2.

[0037] In some preferred embodiments, the thickener is selected from one or more of cellulose, cellulose gum, carbomer, hydroxypropyl guar gum, sodium alginate, xanthan gum, gum arabic, and gelatin; preferably, the thickener is carbomer and xanthan gum.

[0038] In some preferred embodiments, the carbomer is selected from one or more of carbomer 934, carbomer 940, carbomer 980, carbomer 941, carbomer 1342, carbomer Ultrez 10 polymer, carbomer Ultrez 20 polymer, and carbomer Ultrez 30 polymer; preferably, the carbomer gum is carbomer 980.

[0039] In some preferred embodiments, the mass ratio of the carbomer gum to xanthan gum is (2 - 4):1; preferably, the mass ratio of the carbomer gum to xanthan gum is 3.5:1.

[0040] In some preferred embodiments, the surfactant is selected from one or more of PPG-26-buteth-26, carboxybetaine, cetearyl olivate-sorbitan olivate, PEG-40 hydrogenated castor oil cetearyl alcohol, and polysorbate-80; preferably, the surfactant is a mixture of sorbitan olivate and cetearyl alcohol.

[0041] In some preferred embodiments, the weight ratio of the mixture of sorbitan olivate to cetearyl alcohol is (0.8 - 2.5):(2.0 - 4.0); preferably 1.8:3.0.

[0042] The mixture of sorbitan olivate is a mixture of cetearyl olivate and sorbitan olivate.

[0043] Preferably, the described eye contour conditioning composition for firming and stabilizing is particularly suitable for preparing eye care products.

[0044] Beneficial effects:

[0045] (1) This application adds extracts such as Ganoderma lucidum extract, Gynostemma pentaphyllum extract, and Centaurea cyanus extract, which helps to promote the metabolism of eye skin cells, plays a role in moisturizing, delaying the aging of the body, whitening and anti-inflammatory, astringing pores, enhancing skin defense and immune functions, and is suitable for various skin types such as oily skin, dry skin, pigmented skin, and wrinkled skin, especially suitable for people with serious eye pigmentation, fine eye lines, and many wrinkles caused by overuse of eyes.

[0046] (2) The composition prepared by proportionally compounding specific components such as barrier repair agents, emollients, hydroxy compounds, surfactants, thickeners, and chelating agents in this application has good heat resistance and cold resistance properties, good stability. When this composition is used in skin care products, it can be used to improve the fragrance, promote absorption, with a good fragrance and fast absorption. At the same time, this composition can be stored for a long time in skin care products, promote the regeneration of eye skin cells, maintain and regulate skin moisture, restore skin elasticity, delay the aging of the body, have antioxidant whitening, anti-inflammatory and antibacterial effects, and can inhibit the formation and precipitation of melanin in the skin, effectively remove dark circles, astringe pores, and firm the eye skin. In addition, it is smooth when applied, does not show the phenomenon of pilling, and also avoids further deepening of eye fine lines due to the difficult control of strength during the application process, and can meet the multiple needs of different skin types for anti-wrinkle, dark circle removal, etc.

[0047] (3) Through a specific preparation process in this application, combined with the eye contour conditioning composition, it solves the problems of slow absorption speed, poor extensibility, and difficulty in maintaining the fragrance for a long time when the composition is applied to the eye area. Through the effects of sodium hyaluronate, trehalose, Fraxinus excelsior bark extract, Ganoderma lucidum extract, etc., the composition maintains an appropriate viscosity, has good extensibility, and a long-lasting fragrance, improving the practicality of the composition. Description of the drawings

[0048] Figure 1 . DPPH free radical (1,1-diphenyl-2-trinitrophenylhydrazine free radical) scavenging test result diagram of Gynostemma pentaphyllum extract;

[0049] Figure 2 . ABTS free radical (2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) free radical) scavenging test result diagram of Ganoderma lucidum extract. Detailed implementation manners

[0050] Example 1.

[0051] 1. Application of a firming and stabilizing eye area conditioning composition in skin care products, wherein the firming and stabilizing eye area conditioning composition is used to improve the fragrance and absorption rate of skin care products.

[0052] The preparation method of the firming and stabilizing eye area conditioning composition comprises the following steps:

[0053] (1) Add a thickening agent to a preparation pot filled with water, turn on bottom homogenization until evenly dispersed without white lumps, and then start heating under stirring to obtain mixture A;

[0054] (2) Add a surfactant, an emollient, and a hydroxy compound to another stirring pot, heat and stir to mix to obtain mixture B;

[0055] (3) Mix mixture A and mixture B, then homogenize and stir both inside and outside, and cool down to 42.5 ± 2.5 °C to obtain mixture C;

[0056] (4) Add a barrier repair agent to mixture C, homogenize and stir for sampling inspection, and after passing the inspection, filter with a 200-mesh filter cloth and discharge to obtain the product.

[0057] In step (1), the homogenization frequency is 25 Hz, the time is 15 min, the stirring frequency is 25 Hz, and the heating temperature is 85 °C.

[0058] In step (2), the heating temperature is 85 °C.

[0059] In step (3), the homogenization and stirring frequency is 30 Hz, the inside and outside stirring frequency is 25 Hz, and the homogenization and stirring time is 6 min. The homogenization and stirring time in step (3) is 9 min.

[0060] In step (4), the homogenization and stirring time is 9 min.

[0061] The weight ratio of the barrier repair agent, emollient, hydroxy compound, thickening agent, and surfactant is 13:10:7:0.4:5.0.

[0062] The barrier repair agent is a mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, a mixture of Centaurea cyanus extract, hydroxypinacolone retinoate mixture, panthenol, a mixture of Fraxinus excelsior bark extract, a mixture of dipeptide-2 and palmitoyl tetrapeptide-7, a mixture of 1,3-propanediol and Centaurea cyanus extract, a mixture of coffee extract, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, and a mixture of 3-O-ethyl ascorbic acid.

[0063] The mixture of Centaurea cyanus extract is a mixture of triglyceride caprylate / caprate and Centaurea cyanus extract (purchased from Shanghai Pu'en, Gatuline IN-Tense).

[0064] The hydroxy-pinacolone retinoate mixture is a mixture of isosorbide dimethyl ether and hydroxy-pinacolone retinoate (purchased from Shanghai Yanzhen, Granactive Retinoid).

[0065] The Fraxinus excelsior bark extract mixture is a mixture of butylene glycol, water, niacinamide, Fraxinus excelsior bark extract and silanetriol (purchased from Shanghai Pun, Cytobio TM Lumin-Eye).

[0066] The dipeptide-2 and palmitoyl tetrapeptide-7 mixture is a mixture of water, glycerin, hesperidin methyl chalcone, steareth, dipeptide-2 and palmitoyl tetrapeptide-7 (purchased from Shanghai Aoyuan, Eyeliss).

[0067] The coffee extract mixture is a mixture of coffee (Coffea Arabica) extract and cyclodextrin (purchased from Shanghai Tongyi Chemistry).

[0068] Both the Gynostemma pentaphyllum extract and Ganoderma lucidum extract are sourced from Jinhua Shouxian Valley Pharmaceutical Co., Ltd.

[0069] The 3-O-ethyl ascorbic acid mixture is a mixture of water-glycerol-soybean lecithin, 1,3-propanediol, 1,2-hexanediol, 3-O-ethyl ascorbic acid, acetyl hexapeptide-8, cholesterol, octanoyl hydroxamic acid and disodium EDTA (purchased from Shanghai Miaosen Chemical Industry, Nalingyue).

[0070] The mass ratio of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Chrysanthemum coronarium extract mixture, hydroxy-pinacolone retinoate mixture, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Chrysanthemum coronarium extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid mixture is 0.5:0.5:0.5:1:0.1:3.0:0.1:0.5:3.0:1.0:2.0:0.5:0.35:0.01:0.01:0.5.

[0071] The emollient is octyldodecanol, phytosteryl oleate, squalane, tocopheryl acetate and cyclopentasiloxane.

[0072] The squalane is phytosqualane; the source of the phytosqualane is olive oil (purchased from Shanghai Pun, OLIVE SQUALANE);

[0073] The phytosteryl oleate is TS phytosteryl oleate, purchased from Shandong Tiansheng.

[0074] The mass ratio of octyldodecanol, phytosteryl oleate, squalane, tocopherol acetate and cyclopentasiloxane is 3.0:2.0:3.0:0.1:2.0.

[0075] The hydroxy compound is a mixture of glycerol, glyceryl polyether-26 and caprylyl glycol.

[0076] The caprylyl glycol mixture is a mixture of isoprene glycol, caprylyl glycol, 1,2-hexanediol, p-hydroxyacetophenone and dipropylene glycol (purchased from Shanghai Haotai, HT5688).

[0077] The mass ratio of the mixture of glycerol, glyceryl polyether-26 and caprylyl glycol is 3.0:3.0:1.2.

[0078] The thickeners are carbomer and xanthan gum.

[0079] The mass ratio of the carbomer gum to the xanthan gum is 3.5:1;

[0080] The carbomer gel is carbomer 980 (Shanghai Zhaoheng Industry).

[0081] The xanthan gum was purchased from Shanghai Hongjiu, CG-T.

[0082] The surfactant is a sorbitan olivate mixture and cetearyl alcohol.

[0083] The weight ratio of the sorbitan olivate mixture to cetearyl alcohol is 2:3.

[0084] The sorbitan olivate mixture is a mixture of a cetearyl olivate mixture and a sorbitan olivate mixture (purchased from Shanghai Ronghai Biological, Olivem 1000).

[0085] Embodiment 2:

[0086] 1. Application of a firming and stabilizing eye periorbital conditioning composition in skin care products, which is different from Example 1 in that:

[0087] The barrier repair agent is a mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, golden button flower extract (Lanzhou Waterless Biotechnology Co., Ltd.), panthenol, a mixture of European ash bark extract, a mixture of palmitoyl tetrapeptide-3, a mixture of 1,3-propylene glycol and schizonepeta extract, caffeine, arginine, gynostemma pentaphyllum extract, ganoderma lucidum extract, 3-O-ethyl ascorbic acid and acetyl hexapeptide-8;

[0088] The mass ratio of the mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Spilanthes acmella flower extract, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Centaurea cyanus extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid mixture is 0.4:0.6:0.3:1:0.2:2.5:0.4:2.7:0.8:2.0:0.5:0.3:0.01:0.02:0.6.

[0089] The palmitoyl tetrapeptide-3 mixture is a mixture of dipeptide-2 - hesperidin methyl chalcone - palmitoyl tetrapeptide-3 (purchased from Shanghai Aoyuan, Eyeliss polypeptide).

[0090] 2. Application of a firming and stabilizing eye contour conditioning composition in skin care products for preparing eye skin care products.

[0091] Comparative Example 1:

[0092] 1. Application of a firming and stabilizing eye contour conditioning composition in skin care products, which is different from Example 1 in that:

[0093] The barrier repair agent is a mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, Spilanthes acmella flower extract, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Centaurea cyanus extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid mixture.

[0094] 2. Application of a firming and stabilizing eye contour conditioning composition in skin care products for preparing eye skin care products.

[0095] Comparative Example 2:

[0096] 1. Application of a firming and stabilizing eye contour conditioning composition in skin care products, which is different from Example 1 in that:

[0097] The barrier repair agent is a mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, hydroxypinacolone retinoate mixture, panthenol, Fraxinus excelsior bark extract mixture, dipeptide-2 and palmitoyl tetrapeptide-7 mixture, 1,3-propanediol and Centaurea cyanus extract mixture, coffee extract mixture, arginine, Gynostemma pentaphyllum extract, Ganoderma lucidum extract, 3-O-ethyl ascorbic acid mixture;

[0098] 2. Application of a firming and stabilizing eye contour conditioning composition in skin care products for preparing eye skin care products.

[0099] Comparative Example 3:

[0100] 1. An eye cream for removing dark circles with repair and anti-wrinkle effects, which is different from Example 1 in that:

[0101] The barrier repair agent is a mixture of sodium hyaluronate, trehalose, betaine, dipalmitoyl hydroxyproline, hydrogenated lecithin, a mixture of Centaurea cyanus L. extract, panthenol, a mixture of Fraxinus excelsior L. bark extract, a mixture of dipeptide-2 and palmitoyl tetrapeptide-7, a mixture of 1,3-propanediol and Centaurea cyanus L. extract, a mixture of coffee extract, arginine, Gynostemma pentaphyllum (Thunb.) Makino extract, Ganoderma lucidum (Leyss. ex Fr.) Karst. extract, and a mixture of 3-O-ethyl ascorbic acid.

[0102] 2. Application of a firming and stabilizing eye area conditioning composition in skin care products for preparing eye skin care products.

[0103] Performance test:

[0104] 1. Appearance: white to light yellow cream;

[0105] Aroma: The samples were placed at 40 °C for 1 week and then at 5 °C for 1 week in sequence, and then the aroma was measured by aroma appraisers.

[0106] 2. Physical and chemical properties: According to the national standard QB / T 1857-2004 "Emollient Cream", the viscosity of the eye and lip creams obtained in the examples and comparative examples was tested.

[0107] Table 1 Test results of examples and comparative examples

[0108]

[0109] In addition, the DPPH free radical scavenging rate test was carried out on the Gynostemma pentaphyllum (Thunb.) Makino extract, and the ABTS free radical scavenging test was carried out on the Ganoderma lucidum (Leyss. ex Fr.) Karst. extract. The specific methods are as follows:

[0110] 1) DPPH free radical scavenging rate test of Gynostemma pentaphyllum (Thunb.) Makino extract

[0111] The Gynostemma pentaphyllum (Thunb.) Makino extract was prepared into a test solution with a corresponding concentration. The reaction system was prepared according to the addition amounts of each reagent in the following table, mixed well, and 3 replicates were set for each concentration, and 1 background control well was set.

[0112]

[0113] The reaction system was placed at room temperature and reacted in the dark for 20 min. After the reaction was completed, the absorbance OD value was measured at 515 nm, and the scavenging rate of the sample to DPPH free radicals was calculated according to the following formula.

[0114]

[0115] Where: C1 is the absorbance value of the blank DPPH system; C2 is the absorbance value of the blank without DPPH system; T1 is the absorbance value of the sample group with DPPH system; T2 is the absorbance value of the sample group without DPPH system.

[0116] The results of the in vitro DPPH free radical scavenging test of the Gynostemma pentaphyllum extract are shown in the following table and Figure 1 :

[0117]

[0118] The Ganoderma lucidum extract sample was diluted with PBS and reserved for use. The sample concentrations are as follows:

[0119]

[0120] 2) ABTS free radical scavenging test of Ganoderma lucidum extract

[0121] The Ganoderma lucidum extract sample was prepared into a test solution with a corresponding concentration. The reagent addition amounts were configured to form a reaction system in a 96-well plate, mixed well. Three replicate wells were set for each concentration, and one background control well was set.

[0122] unit C1 C2 T1 T2 ABTS working solution 200 0 200 0 test solution 0 0 10 10 PBS 0 200 0 200 sample solvent 10 10 0 0

[0123] After incubating at room temperature for 2 - 6 minutes, the absorbance OD value was read at 734 nm, and the scavenging rate of the sample on ABTS free radicals was calculated.

[0124] Calculation method of scavenging rate:

[0125]

[0126] Where: C1 is the absorbance value of the blank ABTS system; C2 is the absorbance value of the blank without ABTS system; T1 is the absorbance value of the sample group with ABTS system; T2 is the absorbance value of the sample group without ABTS system.

[0127] The results of the in vitro ABTS free radical scavenging test of the Ganoderma lucidum extract are shown in the following table and Figure 2 .

[0128]

Claims

1. A firming and stabilizing eye periorbital conditioning composition for use in skin care products, characterized in that: The firming, stabilizing eye periorbital conditioning composition includes at least a barrier repair agent and an emollient to improve the fragrance and absorption rate of skin care products.

2. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 1 in skin care products, characterized in that: The preparation method of the firming and stabilizing eye periorbital conditioning composition comprises the following steps: (1) Add the thickener to a preparation pot containing water, open the bottom of the pot to homogenize until the mixture is evenly dispersed without any white lumps, and then heat the mixture while stirring to obtain a mixture A; (2) adding the surfactant, emollient, and hydroxy compound into another stirring pot, heating, stirring, and mixing, to obtain a mixture B; (3) Mixing mixture A and mixture B, stirring them homogeneously and stirring them internally and externally, and cooling them to 30-50° C. to obtain mixture C; (4) Add the barrier repair agent to the mixture C, stir it homogenously and take samples for inspection. If it is qualified, filter and discharge the material.

3. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 2 in skin care products, characterized in that: In the step (1), the homogenization frequency is 10-30 Hz, the time is 5-40 min, the stirring frequency is 10-50 Hz, and the heating temperature is 60-90° C.

4. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 3 in skin care products, characterized in that: In the step (1), the homogenization frequency is 15-25 Hz, the time is 10-25 min, the stirring frequency is 20-30 Hz, and the heating temperature is 70-95° C.

5. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 2 in skin care products, characterized in that: The heating temperature in step (2) is 75-100°C.

6. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 2 in skin care products, characterized in that: The filtration in step (4) is specifically performed using a 200-mesh filter cloth.

7. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 2 in skin care products, characterized in that: The surfactant is selected from one or more of PPG-26-butanol polyether-26, carboxylic acid betaine, cetearyl olivate-sorbitan olivate, PEG-40 hydrogenated castor oil cetearyl alcohol, and polysorbate-80.

8. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 7 in skin care products, characterized in that: The surfactant is cetearyl olivate-sorbitan olivate and cetearyl alcohol.

9. Use of a firming and stabilizing eye periorbital conditioning composition according to claim 2 in skin care products, characterized in that: The weight ratio of the barrier repair agent, the emollient, the hydroxy compound, the thickener and the surfactant in the composition is (8-15): (5-13): (3-8.5): (0.2-0.6): (3-6.5).

10. Use of a firming and stabilizing eye periorbital conditioning composition according to any one of claims 1 to 9 in skin care products, characterized in that: The composition is used for preparing eye skin care products.

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