A method and kit for enriching circulating tumor cells of liver cancer using GPC3 combined with MERTK

CN120427356BActive Publication Date: 2025-09-02HANGZHOU WATSON BIOTECH INC
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Patent Information

Application Number
CN202510934353.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-07-08
Publication Date
2025-09-02
Estimated Expiration
2045-07-08

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Abstract

This invention belongs to the field of biomedicine and specifically relates to a method and kit for enriching circulating tumor cells (CTCs) in liver cancer using GPC3 in combination with MERTK. This method combines MERTK with traditional markers such as EpCAM, vimentin, and GPC3 to capture circulating tumor cells in liver cancer, achieving improved enrichment of CTCs. This method and its accompanying kit are widely applicable to early screening of liver cancer, postoperative recurrence monitoring, metastasis risk assessment, and personalized treatment management, and has promising prospects for clinical translation.
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