Traditional Chinese medicine composition with functions of invigorating stomach and soothing liver as well as preparation method and application of traditional Chinese medicine composition
Through the preparation method of decoding and concentrating traditional Chinese medicine compositions, the problem of major side effects of Western medicine in treating chronic gastritis and hepatitis is solved, and effective treatment of chronic gastritis and hepatitis is achieved, and it has significant effect of strengthening the stomach and sootheing the liver.
Patent Information
- Application Number
- CN202510773909.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-11
- Publication Date
- 2025-08-29
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Current Western medicines for the treatment of chronic gastritis and chronic hepatitis have great side effects and are prone to recurrence, and long-term use of chemical drugs has serious health impacts.
It adopts a traditional Chinese medicine composition, consisting of medicinal materials such as Atractylodes, Atractylodes, Tangerine peel, White Cardamom, Jiao Sanxian, Pinellia ternata, Muxiang, Citrus aurantium, Xiangfu, betel nut, licorice, Bupleurum, Red Peony, White Peony and Yujin. It is prepared into dosage forms such as pills through decoction and concentration, and is targeted for the treatment of diseases such as liver depression and spleen deficiency in indigestion and chronic gastritis.
The traditional Chinese medicine composition has the function of strengthening the stomach and relieving the liver, with few side effects, and can fundamentally treat diseases, significantly improve the effects of drying dampness, strengthening the spleen, relieving liver and relieving depression, significantly improve the symptoms of chronic gastritis and chronic hepatitis, and the overall effective efficiency is higher than alternative solutions.
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions, and a preparation method and application thereof. Background Art
[0002] Chronic gastritis is a chronic inflammation of the gastric mucosa caused by various etiologies. Based on histopathological changes and the distribution of lesions in the stomach, combined with possible etiologies, chronic gastritis is divided into three categories: non-atrophic, atrophic, and special types. Patients with chronic gastritis mainly experience indigestion symptoms such as upper abdominal pain or discomfort, upper abdominal distension, early satiety, belching, and nausea. The current common treatment method is to use antacids, acid suppressants, gastrointestinal prokinetics, and gastric mucosal protective drugs for treatment, starting from the affected area. However, most current Western medicines have side effects and are prone to relapse after discontinuation of medication.
[0003] Chronic hepatitis refers to chronic liver inflammation lasting for more than six months. It is divided into two types: chronic persistent hepatitis and chronic active hepatitis. Symptoms of chronic hepatitis include frequent or recurring fatigue, pain in the liver area, abdominal distension, decreased work ability and general health, an enlarged and tender liver, and possibly an enlarged spleen. Currently, chronic hepatitis is generally treated with drugs such as polyene phosphatidylcholine, glycyrrhizic acid, and silymarin. However, these drugs require long-term medication, which can have significant side effects and severely impact patients' health. Summary of the Invention
[0004] In response to the above-mentioned deficiencies in the prior art, the present invention provides a traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions, as well as a preparation method and application thereof. The traditional Chinese medicine composition has a good therapeutic effect on chronic gastritis and chronic hepatitis, with fewer side effects and less impact on the human body, and can fundamentally treat the causes of the diseases.
[0005] To achieve the above-mentioned purpose, the technical solution adopted by the present invention to solve the technical problem is:
[0006] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 30-70 parts of atractylodes lancea, 30-70 parts of white atractylodes, 30-50 parts of dried tangerine peel, 20-40 parts of white cardamom, 30-70 parts of Jiao Sanxian, 30-70 parts of French pinellia, 20-40 parts of costus root, 30-50 parts of fructus aurantii, 30-70 parts of cyperus rotundus, 30-70 parts of areca catechu, 20-40 parts of liquorice, 30-70 parts of bupleurum, 30-70 parts of red peony root, 30-70 parts of white peony root and 15-35 parts of turmeric.
[0007] Further, the invention includes the following components in parts by weight: 45-55 parts of Atractylodes lancea, 45-55 parts of Atractylodes macrocephala, 35-45 parts of dried tangerine peel, 25-35 parts of white cardamom, 45-55 parts of Jiao Sanxian, 45-55 parts of French Pinellia, 25-35 parts of costus root, 35-45 parts of Citrus aurantium, 45-55 parts of Cyperus rotundus, 45-55 parts of Areca catechu, 25-35 parts of licorice, 45-55 parts of Bupleurum chinense, 45-55 parts of red peony root, 45-55 parts of white peony root and 20-30 parts of Curcuma aromatica.
[0008] Further, it includes the following components in parts by weight: 45 parts of Atractylodes lancea, 55 parts of Atractylodes macrocephala, 45 parts of dried tangerine peel, 25 parts of white cardamom, 45 parts of Jiao Sanxian, 45 parts of French Pinellia, 25 parts of costus root, 45 parts of Citrus aurantium, 55 parts of Cyperus rotundus, 45 parts of Areca catechu, 35 parts of Licorice, 55 parts of Bupleurum chinense, 55 parts of Red Peony Root, 45 parts of White Peony Root and 20 parts of Curcuma aromatica.
[0009] Further, it includes the following components in parts by weight: 55 parts of Atractylodes lancea, 45 parts of Atractylodes macrocephala, 35 parts of dried tangerine peel, 35 parts of white cardamom, 55 parts of Jiao Sanxian, 55 parts of French Pinellia, 35 parts of costus root, 35 parts of Citrus aurantium, 45 parts of Cyperus rotundus, 55 parts of Areca catechu, 25 parts of Licorice, 45 parts of Bupleurum chinense, 45 parts of Red Peony Root, 55 parts of White Peony Root and 30 parts of Curcuma aromatica.
[0010] Further, it includes the following components in parts by weight: 50 parts of Atractylodes lancea, 50 parts of Atractylodes macrocephala, 40 parts of dried tangerine peel, 30 parts of white cardamom, 50 parts of Jiao Sanxian, 50 parts of French Pinellia, 30 parts of costus root, 40 parts of Citrus aurantium, 50 parts of Cyperus rotundus, 50 parts of Areca catechu, 30 parts of Licorice, 50 parts of Bupleurum chinense, 50 parts of Red Peony Root, 50 parts of White Peony Root and 25 parts of Curcuma aromatica.
[0011] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver comprises the following steps: crushing the raw materials and then mixing them; or preparing the composition by mixing or extracting the raw materials separately to obtain an extract; or preparing the composition by further refining and purifying the extract to obtain an effective ingredient; or preparing the composition by adding pharmaceutically acceptable excipients to the extract / active ingredient.
[0012] Furthermore, the prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.
[0013] Furthermore, the specific preparation method is: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water, the decoction is collected, concentrated into a clear paste, mixed with the above fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0014] Furthermore, the decoction is performed twice, and the decoction time for each time is 0.5-1.5 hours.
[0015] Application of the above-mentioned traditional Chinese medicine composition in preparing medicine for treating chronic gastritis or chronic hepatitis.
[0016] The beneficial effects produced by the present invention are:
[0017] In the present invention, Atractylodes macrocephala dries dampness and strengthens the spleen, dispels wind and cold, and is good at treating abdominal distension and loose stools caused by dampness blocking the middle jiao; Atractylodes macrocephala tonifies qi and strengthens the spleen, dries dampness and promotes diuresis, and enhances the transportation and transformation function of the spleen and stomach. Atractylodes macrocephala is bitter and warm and dries dampness, while Atractylodes macrocephala is sweet and warm and strengthens the spleen. The combination of the two significantly improves the effect of drying dampness and strengthening the spleen; Bupleurum chinense soothes the liver and relieves depression, and is a key medicine for soothing the liver and regulating qi. The liver is responsible for regulating qi, and Bupleurum chinense ascends and disperses, directly reaching the liver meridian, and relieving the root of liver depression and qi stagnation. The above are all monarch drugs, and play a major therapeutic role in treating liver depression and spleen deficiency.
[0018] Curcuma soothes the liver and relieves depression, promotes blood circulation and relieves pain, and can help Bupleurum soothe the liver and regulate qi, while also promoting blood circulation and preventing liver depression and blood stasis. Its cold nature can prevent the warm and dry main herbs from damaging yin. Red peony root clears heat and cools blood, promotes blood circulation and removes blood stasis, and can prevent liver depression from turning into heat or blood stasis. White peony root nourishes blood and regulates menstruation, softens the liver and relieves pain, and its sour and sweet properties can astringe yin, preventing pungent and dispersing herbs from damaging liver yin. These are collectively referred to as assistant herbs.
[0019] Tangerine peel regulates qi and strengthens the spleen, dries dampness and resolves phlegm, and can relieve abdominal distension. Pinellia ternata dries dampness and resolves phlegm, harmonizes the stomach and stops vomiting, and has a relieving effect on fullness and loss of appetite caused by dampness blocking the middle jiao. Both are products that dry dampness and resolve phlegm, which can enhance the function of the main medicine to remove dampness and harmonize the stomach; Jiao Sanxian has the effects of digesting food and resolving accumulation, harmonizing the stomach and stopping vomiting, and can assist Atractylodes macrocephala and Atractylodes macrocephala in strengthening the spleen and stomach; costus root promotes qi and relieves pain, strengthens the spleen and digests food, and is especially good at unblocking spleen and stomach qi stagnation, relieving abdominal distension; Citrus aurantium breaks up qi and resolves accumulation, resolves phlegm and eliminates fullness, and is comparable to costus root. The herbs are used to promote the flow of qi and dissipate bloating; Areca nut promotes the flow of qi and dissipates phlegm, eliminates stagnation and relieves stagnation; Aucklandia lappa, Citrus aurantium, and Areca nut are used together to promote the flow of qi and dissipate phlegm to help digestion; White cardamom eliminates dampness and promotes qi, warms the middle and stops vomiting, enters the spleen and stomach meridians, and can lead all the other herbs directly to the middle burner, enhancing the effect of removing dampness and harmonizing the stomach; Cyperus rotundus soothes the liver and regulates qi, regulates menstruation and relieves pain, specifically enters the liver meridian qi, and enhances the power of Bupleurum to soothe the liver and relieve depression, with a good therapeutic effect for chest tightness and flank distension caused by liver depression and qi stagnation. The above are all adjuvants; Licorice harmonizes all the other herbs as a guiding drug. The various medicinal materials in the composition of the present invention complement each other and have a good therapeutic effect on diseases such as liver depression and spleen deficiency type indigestion, chronic gastritis, and chronic hepatitis. DETAILED DESCRIPTION
[0020] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention. That is, the embodiments described are only part of the embodiments of the present invention, rather than all embodiments.
[0021] Therefore, the detailed description of the embodiments of the present invention provided below is not intended to limit the scope of the invention as claimed, but is merely intended to represent selected embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative work are within the scope of protection of the present invention.
[0022] It should be noted that relational terms such as "first" and "second" are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or apparatus comprising the element.
[0023] The features and performance of the present invention are further described in detail below with reference to the embodiments.
[0024] Example 1
[0025] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 30 parts of atractylodes lancea, 70 parts of white atractylodes, 50 parts of dried tangerine peel, 20 parts of white cardamom, 30 parts of Jiao Sanxian, 30 parts of French pinellia, 20 parts of costus root, 50 parts of bitter orange, 70 parts of cyperus rotundus, 30 parts of areca catechu, 40 parts of liquorice, 70 parts of bupleurum, 70 parts of red peony root, 30 parts of white peony root and 15 parts of curcuma.
[0026] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0027] Example 2
[0028] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 70 parts of atractylodes lancea, 30 parts of white atractylodes, 30 parts of dried tangerine peel, 40 parts of white cardamom, 70 parts of Jiao Sanxian, 70 parts of French pinellia, 40 parts of costus root, 30 parts of fructus aurantii, 30 parts of cyperus rotundus, 70 parts of areca catechu, 20 parts of liquorice, 30 parts of bupleurum, 30 parts of red peony root, 70 parts of white peony root and 35 parts of turmeric.
[0029] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0030] Example 3
[0031] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 55 parts of atractylodes lancea, 45 parts of white atractylodes, 35 parts of dried tangerine peel, 35 parts of white cardamom, 55 parts of Jiao Sanxian, 55 parts of French pinellia, 35 parts of costus root, 35 parts of bitter orange, 45 parts of cyperus rotundus, 55 parts of areca catechu, 25 parts of liquorice, 45 parts of bupleurum, 45 parts of red peony root, 55 parts of white peony root and 30 parts of curcuma.
[0032] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0033] Example 4
[0034] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 45 parts of atractylodes lancea, 55 parts of white atractylodes, 45 parts of dried tangerine peel, 25 parts of white cardamom, 45 parts of jiaosanxian, 45 parts of pinellia, 25 parts of costus root, 45 parts of fructus aurantii, 55 parts of cyperus rotundus, 45 parts of areca catechu, 35 parts of liquorice, 55 parts of bupleurum, 55 parts of red peony root, 45 parts of white peony root and 20 parts of turmeric.
[0035] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0036] Example 5
[0037] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 50 parts of atractylodes lancea, 50 parts of white atractylodes, 40 parts of dried tangerine peel, 30 parts of white cardamom, 50 parts of Jiao Sanxian, 50 parts of French pinellia, 30 parts of costus root, 40 parts of fructus aurantii, 50 parts of cyperus rotundus, 50 parts of areca catechu, 30 parts of liquorice, 50 parts of bupleurum, 50 parts of red peony root, 50 parts of white peony root and 25 parts of turmeric.
[0038] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0039] Comparative Example 1
[0040] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 50 parts of Amomum villosum, 50 parts of Poria cocos, 40 parts of dried tangerine peel, 30 parts of white cardamom, 50 parts of Jiao Sanxian, 50 parts of French pinellia, 30 parts of costus root, 40 parts of bitter orange, 50 parts of Cyperus rotundus, 50 parts of Areca catechu, 30 parts of liquorice, 50 parts of Cimicifuga heracleifolia, 50 parts of red peony root, 50 parts of white peony root and 25 parts of Curcuma aromatica.
[0041] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0042] Comparative Example 2
[0043] A traditional Chinese medicine composition with stomach-strengthening and liver-soothing functions comprises the following components in parts by weight: 50 parts of atractylodes lancea, 50 parts of white atractylodes, 40 parts of dried tangerine peel, 30 parts of white cardamom, 50 parts of pinellia, 30 parts of costus root, 40 parts of fructus aurantii, 50 parts of cyperus rotundus, 50 parts of areca catechu, 30 parts of liquorice, 50 parts of bupleurum, 50 parts of red peony root, 50 parts of white peony root and 25 parts of ligusticum.
[0044] The preparation method of the above-mentioned traditional Chinese medicine composition with the function of strengthening the stomach and soothing the liver is as follows: the above fifteen ingredients, tangerine peel and white cardamom are crushed into fine powder, the remaining medicines are decocted with water twice, and the amount of water added each time is 3 times the weight of the medicinal materials. Each decoction is decocted for 1 hour, the decoction is collected, concentrated into a clear paste, mixed with the above-mentioned fine powder and added with appropriate amount of auxiliary materials, and made into pills.
[0045] Test example
[0046] 1. General Information
[0047] 60 patients with chronic hepatitis and chronic gastritis who came to the hospital for treatment were collected, aged between 20 and 65 years old.
[0048] 2. Disease Diagnostic Criteria
[0049] (1) Chronic gastritis
[0050] Epigastric pain, with epigastric pain as the main symptom, which may be accompanied by bloating, acid reflux, belching, etc.
[0051] Piman is characterized by fullness and distension in the epigastric region that is invisible to the touch, soft to the touch, and painless to pressure.
[0052] Noisy, with empty stomach, feeling hungry but not hungry, feeling spicy but not spicy, feeling painful but not painful as the main symptoms, and may be accompanied by heartburn.
[0053] (2) Chronic hepatitis
[0054] Hypochondriac pain: The main symptom is pain in one or both sides of the ribs, which may be accompanied by abdominal distension and fatigue;
[0055] Jaundice: Characterized by yellow eyes, body, and urine, it is often seen in cases of damp-heat in the liver and gallbladder or dampness in the spleen;
[0056] Ascites: Symptoms include a distended abdomen, pale skin, and exposed veins, corresponding to the ascites stage of cirrhosis;
[0057] Accumulation: Characterized by a sub-rib mass (hepatosplenomegaly), it needs to be differentiated from liver fibrosis and cirrhosis in Western medicine.
[0058] III. Inclusion Criteria
[0059] (1) Conform to the Chinese medicine dialectical standards;
[0060] (2) Age 20–65 years old;
[0061] (3) Volunteer to serve as a subject and receive drug treatment.
[0062] IV. Exclusion criteria
[0063] (1) Pregnant or breastfeeding women;
[0064] (2) Those who have been taking other Chinese and Western medicines for a long time and are difficult to stop taking them;
[0065] (3) Those who fail to use the medication according to the prescribed instructions, whose efficacy cannot be judged or whose data are incomplete and affect the judgment of efficacy.
[0066] 5. Dosage Method
[0067] Patients with confirmed chronic gastritis and chronic hepatitis were randomly divided into three groups, each with 20 people. Each group of patients was given the drugs in Example 5 and Comparative Examples 1-2 three times a day, 10 g each time, each g equivalent to 1.35 g of the original medicinal material, for 30 consecutive days, and the treatment status of the patients was observed.
[0068] VI. Efficacy Evaluation Criteria
[0069] Syndrome score refers to the classification of the patient's symptoms into four levels: none, mild, moderate, and severe. No symptoms are marked as 0 points, mild as 2 points, moderate as 4 points, and severe as 6 points. The total score of all symptoms is the patient's total symptom score.
[0070] Symptom score reduction rate = (symptom score before treatment - symptom score after treatment) / symptom score before treatment * 100%
[0071] (1) Chronic gastritis:
[0072] Clinical cure: The main symptoms such as epigastric pain, fullness, and noisy stomach disappear, and the secondary symptoms basically disappear, with the symptom score reduction rate ≥95%;
[0073] Markedly effective: The main symptoms are significantly relieved, the secondary symptoms are improved, and the reduction rate of syndrome score is ≥70% and <95%;
[0074] Effective: The main symptoms are alleviated, the secondary symptoms are partially improved, and the syndrome score reduction rate is ≥30% and <70%;
[0075] Ineffective: No improvement or worsening of symptoms, with a symptom score reduction rate of <30%;
[0076] (2) Chronic hepatitis:
[0077] Clinical cure: score reduction rate ≥ 95%, symptoms disappear, and tongue and pulse return to normal;
[0078] Markedly effective: 70% ≤ integral reduction rate < 95%, with significant relief of the main symptoms and improvement of the secondary symptoms;
[0079] Effective: 30% ≤ integral reduction rate < 70%, symptoms are alleviated;
[0080] Ineffective: The score reduction rate is less than 30%, and the symptoms are not improved or worsen.
[0081] Total effective rate = (number of clinically cured patients + number of markedly effective patients + number of effective patients) / total number of patients * 100%
[0082] 7. Treatment Outcomes
[0083] (1) Chronic gastritis
[0084] Group Clinically cured (people) Significantly effective (people) Effective (person) Invalid (person) Total effective rate (%) Example 5 8 7 4 1 95% Comparative Example 1 2 8 2 8 60% Comparative Example 2 1 10 1 8 60%
[0085] (2) Chronic hepatitis
[0086] Group Clinically cured (people) Significantly effective (people) Effective (person) Invalid (person) Total effective rate (%) Example 5 7 9 3 1 95% Comparative Example 1 1 9 1 9 55% Comparative Example 2 0 9 2 9 55%
[0087] The results in the above table show that the drug in Example 5 has a good therapeutic effect on chronic gastritis and chronic hepatitis, and its therapeutic efficiency is much higher than that of the drugs in Comparative Examples 1 and 2. It is speculated that after the specific medicinal materials in the pharmaceutical compositions of Comparative Examples 1 and 2 are adjusted, the interaction relationship between the medicinal materials is weakened or disappears.
Claims
1. A Chinese medicine composition having stomach-strengthening and liver-soothing functions, characterized in that: The invention comprises the following components in parts by weight: 30-70 parts of atractylodes lancea, 30-70 parts of white atractylodes, 30-50 parts of dried tangerine peel, 20-40 parts of white cardamom, 30-70 parts of Jiao Sanxian, 30-70 parts of French pinellia, 20-40 parts of costus root, 30-50 parts of fructus aurantii, 30-70 parts of cyperus rotundus, 30-70 parts of areca catechu, 20-40 parts of liquorice, 30-70 parts of bupleurum, 30-70 parts of red peony root, 30-70 parts of white peony root and 15-35 parts of turmeric.
2. The Chinese medicine composition having the function of invigorating the stomach and soothing the liver according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 45-55 parts of atractylodes lancea, 45-55 parts of white atractylodes, 35-45 parts of dried tangerine peel, 25-35 parts of white cardamom, 45-55 parts of Jiao Sanxian, 45-55 parts of French pinellia, 25-35 parts of costus root, 35-45 parts of fructus aurantii, 45-55 parts of cyperus rotundus, 45-55 parts of areca catechu, 25-35 parts of liquorice, 45-55 parts of bupleurum, 45-55 parts of red peony root, 45-55 parts of white peony root and 20-30 parts of turmeric.
3. The Chinese medicine composition having the function of strengthening the stomach and soothing the liver according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 45 parts of atractylodes lancea, 55 parts of white atractylodes, 45 parts of dried tangerine peel, 25 parts of white cardamom, 45 parts of jiao sanxian, 45 parts of french pinellia, 25 parts of costus root, 45 parts of fructus aurantii, 55 parts of cyperus rotundus, 45 parts of areca catechu, 35 parts of liquorice, 55 parts of bupleurum, 55 parts of red peony root, 45 parts of white peony root and 20 parts of turmeric.
4. The Chinese medicine composition having the function of invigorating the stomach and soothing the liver according to claim 1, wherein The invention comprises the following components in parts by weight: 55 parts of atractylodes lancea, 45 parts of white atractylodes, 35 parts of dried tangerine peel, 35 parts of white cardamom, 55 parts of jiao sanxian, 55 parts of french pinellia, 35 parts of costus root, 35 parts of fructus aurantii, 45 parts of cyperus rotundus, 55 parts of areca catechu, 25 parts of liquorice, 45 parts of bupleurum, 45 parts of red peony root, 55 parts of white peony root and 30 parts of turmeric.
5. The Chinese medicine composition having the function of invigorating the stomach and soothing the liver according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 50 parts of atractylodes lancea, 50 parts of white atractylodes, 40 parts of dried tangerine peel, 30 parts of white cardamom, 50 parts of Jiao Sanxian, 50 parts of French pinellia, 30 parts of costus root, 40 parts of fructus aurantii, 50 parts of cyperus rotundus, 50 parts of areca catechu, 30 parts of liquorice, 50 parts of bupleurum, 50 parts of red peony root, 50 parts of white peony root and 25 parts of turmeric.
6. The method for preparing the Chinese medicinal composition having the function of invigorating the stomach and soothing the liver according to any one of claims 1 to 5, characterized in that: The following steps are involved: It is made by crushing and mixing the raw materials; or by extracting the raw materials by mixing or extracting them separately; or by further refining and purifying the extract to obtain the active ingredient; or by adding pharmaceutically acceptable excipients to the extract / active ingredient.
7. The method for preparing the Chinese medicine composition having the functions of invigorating the stomach and soothing the liver according to claim 6, wherein: The prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.
8. The method for preparing the Chinese medicine composition having the functions of invigorating the stomach and soothing the liver as claimed in claim 7, characterized in that: The specific preparation method is: crush the above fifteen ingredients, tangerine peel, white cardamom and Jiao Sanxian into fine powder, add water to the remaining medicines and boil them, collect the decoction, concentrate it into a clear paste, mix it with the above fine powder and add appropriate amount of auxiliary materials to make pills.
9. The method for preparing the Chinese medicine composition having the functions of invigorating the stomach and soothing the liver as claimed in claim 8, characterized in that: The decoction is performed twice, and each decoction time is 0.5-1.5 hours.
10. Use of the traditional Chinese medicine composition according to any one of claims 1 to 5 in the preparation of a medicament for treating chronic gastritis or chronic hepatitis.