Pteridinone compound and application thereof
By developing pteridinone compounds with specific structures, the problems of large toxic side effects and high drug resistance of existing mTOR inhibitors have been solved, and safe and efficient tumor treatment effects have been achieved.
CN120665071APending Publication Date: 2025-09-19GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCES
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Patent Information
- Application Number
- CN202510730121.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-03
- Publication Date
- 2025-09-19
AI Technical Summary
Technical Problem
Existing mTOR inhibitors have problems such as large toxic side effects, high drug resistance and low bioavailability in treating tumors, and cannot achieve ideal clinical treatment effects.
Method used
Develop a pteridinone compound that, through specific structural design, can effectively inhibit mTOR kinase and has excellent anti-tumor effects. At the same time, it has low toxicity, little damage to organs, and is safe and highly effective.
Benefits of technology
Pteridinone compounds can effectively inhibit mTOR kinase, show excellent anti-tumor effects, low toxicity, little damage to organs, safe and efficient, and solve the toxic side effects and drug resistance problems of existing mTOR inhibitors.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention provides a pteridinone compound and application thereof. The structure of the pteridinone compound is as shown in formula I in the specification. The pteridinone compound provided by the invention can effectively inhibit mTOR kinase, has an excellent anti-tumor effect, and is low in toxicity, small in harm to organs, safe and efficient.
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