A method for constructing a lung cancer xenograft model
By constructing an asthma model in rodents and transplanting lung cancer cells, an asthma-lung cancer xenograft model was established, solving the problem that existing lung cancer models are difficult to simulate clinical characteristics, and achieving higher scientific and application value.
CN120678065BActive Publication Date: 2026-08-07THE CHINESE UNIVERSITY OF HONG KONG
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Patent Information
- Application Number
- CN202410287636.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-13
- Publication Date
- 2026-08-07
- Estimated Expiration
- 2044-03-13
AI Technical Summary
Technical Problem
Existing lung cancer transplantation models are unable to effectively simulate the clinical pathogenesis of lung cancer, resulting in insufficient translation and application value of experimental results.
Method used
By constructing an asthma model in rodents and transplanting rodent-derived lung cancer cells into the asthma model, an asthma-lung cancer xenograft model was established to simulate the development process of clinical lung cancer.
Benefits of technology
A successful lung cancer xenograft model was established that can better simulate clinical findings in basic research, enhancing its scientific and application value and verifying the phenomenon that asthma promotes lung cancer development.
✦ Generated by Eureka AI based on patent content.
Abstract
The application discloses a method for constructing a lung cancer xenograft tumor model, which comprises the following steps: S1, constructing an asthma model by using a sensitizing agent causing asthma on a rodent; S2, establishing the lung cancer xenograft tumor model by transplanting lung cancer cells from the rodent into the asthma model. The lung cancer xenograft tumor model constructed by the application can simulate the findings of clinical research in basic research, and improve the scientific value and application value of the lung cancer xenograft tumor model.
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