Quantitative drug feeding device for mouse experiment

By designing a quantitative drug feeding device for mouse experiments, a transmission connection between a gun-shaped main body and a connecting sealing component is adopted to achieve quantitative adjustment and continuous replenishment of the drug solution. This solves the problems of difficult precise control of drug solution volume and complex operation in existing technologies, and improves experimental efficiency and data reliability.

CN120859708AInactive Publication Date: 2025-10-31SHANXI MEDICAL UNIV
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Patent Information

Application Number
CN202511280537.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-09
Publication Date
2025-10-31
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing methods of drug feeding to mice have problems such as difficulty in accurately controlling the volume of the drug solution, complex operation, lack of quantitative adjustment function, inability to operate continuously, and increased experimental error and risk of contamination.

Method used

A quantitative drug feeding device for mouse experiments is designed, which adopts a gun-shaped main structure. Through the transmission connection between the connecting component and the sealing component, combined with the sliding cooperation of the metering cylinder and the piston, the quantitative adjustment and continuous replenishment of the drug solution can be realized, simplifying the operation process and ensuring the accuracy and safety of the drug solution.

Benefits of technology

It improves experimental efficiency and data reliability, reduces human error and contamination risks, adapts to different experimental needs, and ensures the health of mice and the accuracy of experimental results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of medicine feeding, in particular to a quantitative medicine feeding device for mouse experiments, which comprises a gun-shaped main body, a medicine storage bottle is arranged on the main body, the medicine storage bottle is communicated with a quantitative cylinder arranged at the end part of the main body through a communication component, and the quantitative cylinder is communicated with a medicine feeding pipe; a sealing assembly is arranged on the medicine storage bottle and is in transmission connection with the communicating assembly; a piston in transmission connection with the communication assembly is slidably arranged in the quantitative cylinder, and the piston feeds a mouse with liquid medicine through a medicine feeding pipe; an adjusting assembly corresponding to the piston is arranged at the end of the quantifying cylinder and is in transmission connection with the piston to adjust the position of the piston. The device is compact in structure, convenient to operate and capable of flexibly and conveniently feeding mice with medicine, and the experiment precision is improved; and meanwhile, during administration, continuous supplement of the liquid medicine can be realized, so that continuous operation is realized, the workload is reduced, and the risk that the medicine is polluted is reduced.
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Description

Technical Field

[0001] This invention relates to the field of drug feeding technology, and more particularly to a quantitative drug feeding device for mice in laboratory settings. Background Technology

[0002] In mouse experiments, accurate control of drug dosage is crucial for the reliability and reproducibility of experimental results.

[0003] However, current common methods of drug feeding in mice have many problems. On the one hand, traditional manual feeding methods rely on the experience and skills of the experimenters, making it difficult to precisely control the volume of the drug solution. Human error is unavoidable, leading to variations in the amount of drug solution given each time, which seriously affects the accuracy of experimental data, reduces the comparability between results from different batches, and increases the difficulty of analyzing experimental results. On the other hand, some existing feeding devices are complex in structure and cumbersome in operation, requiring independent operation for each step. This not only reduces experimental efficiency, but also consumes a lot of time and manpower, especially in batch mouse experiments. At the same time, existing mouse drug feeding devices lack quantitative adjustment functions, making it impossible to flexibly adjust the feeding dosage according to different experimental needs, failing to meet diverse experimental requirements, limiting the versatility and flexibility of the device, and failing to effectively prevent drug backflow or external contamination. During the experiment, drug backflow may alter the composition of the drug solution, affecting the accuracy of the experimental results; while external contamination may harm the health of the mice and interfere with the experimental results. Furthermore, existing feeding devices cannot operate continuously. After each feeding, manual replenishment of the medication solution is required before the next feeding can be performed. This not only increases the workload but also prolongs the experimental time and reduces the experimental efficiency. In addition, the risk of drug contamination increases during the manual replenishment process.

[0004] Therefore, the present invention designs a quantitative drug feeding device for mouse experiments to solve the above-mentioned technical problems. Summary of the Invention

[0005] The purpose of this invention is to provide a quantitative feeding device for drugs in mouse experiments, so as to solve the problems existing in the prior art.

[0006] To achieve the above objectives, the present invention provides the following solution: The present invention provides a quantitative feeding device for mice, comprising a gun-shaped main body, a drug storage bottle for storing drug solution on the main body, the drug storage bottle being connected to a metering cylinder disposed at the end of the main body via a connecting component, and the metering cylinder being connected to a feeding tube for feeding drugs to mice.

[0007] The medicine storage bottle is provided with a sealing component for sealing. The sealing component is connected to the communication component. The communication component opens the sealing component to allow the medicine liquid in the medicine storage bottle to enter the metering cylinder.

[0008] A piston, which is slidably connected to the communicating component, is disposed in the metering cylinder, and the piston feeds the drug solution to the mouse through the feeding tube.

[0009] The metering cylinder is provided with an adjustment component at its end, which is corresponding to the piston. The adjustment component is connected to the piston in a driving manner to adjust the position of the piston.

[0010] Preferably, the piston includes a fixed plate that is pulsatorically connected to the communicating component, and a plurality of rotating rods are synchronously rotated on the fixed plate. The plurality of rotating rods are threadedly connected to a movable plate that is slidably connected in the metering cylinder. A flexible plug is fixedly connected to one end of the movable plate away from the fixed plate.

[0011] Preferably, the adjusting assembly includes an adjusting rod rotatably connected to the metering cylinder, a driving gear being drivenly connected to the adjusting rod, the driving gear meshing with a driven gear rotatably connected to the fixed plate, and a rotating rod extending into the fixed plate and being drivenly connected to the driven gear.

[0012] Preferably, the metering cylinder has a feeding chamber, and the piston is slidably sealed in the feeding chamber to press the liquid medicine in the feeding chamber into the feeding tube through the medicine outlet channel; a reset chamber is provided at the end of the feeding chamber away from the connecting component, and a reset spring is provided between the reset chamber and the piston.

[0013] Preferably, the communication component includes a piston rod slidably connected within the body, the piston rod extending into the feeding chamber and being throttledly connected to the piston, and the piston rod being throttledly connected to a feeding trigger disposed on the body, so that pulling the feeding trigger causes the piston to move within the feeding chamber.

[0014] Preferably, the communication component further includes a transfer chamber formed within the main body, the transfer chamber being connected to the feeding chamber via a medication replenishment channel provided on the piston rod, the transfer chamber being connected to the sealing component, and the liquid medicine in the medicine storage bottle being injected into the feeding chamber through the transfer chamber and the medication replenishment channel.

[0015] Preferably, a drive block that is slidably connected to the piston rod is fixedly connected to the transfer cavity, a connecting block is slidably connected to the inclined side of the drive block, a drive rod is hinged to the connecting block, and the drive rod is arranged along the transfer channel communicating with the transfer cavity and is drively connected to the sealing assembly.

[0016] Preferably, the sealing assembly includes a sealing block slidably disposed at the mouth of the medicine storage bottle, and a sealing module for controlling the discharge of the medicine liquid is provided at the end of the sealing block away from the medicine storage bottle; after the medicine storage bottle is installed, the transfer channel pushes open the sealing block, and the drive rod is drivenly connected to the sealing module. When the drive rod moves, it pushes open the sealing module, allowing the medicine liquid to enter the transfer channel.

[0017] Preferably, the sealing module includes a positioning tube fixed to the sealing block, an elastic block that is flexibly connected to the drive rod and slides within the positioning tube, a plurality of sealing rods that are flexibly connected to the elastic block, the sealing rods extending out of the positioning tube and fixed with a flexibly configured sealing plug, and the sealing plug being detachably connected to a medicine outlet hole opened on the sealing block.

[0018] Preferably, the medicine storage bottle is provided with a stirring shaft, which is rotatably connected between the sealing block and the bottom of the medicine storage bottle, and a plurality of stirring rods are fixedly connected to the outer wall of the stirring shaft; the stirring shaft is drivenly connected to the drive rod.

[0019] Compared with existing technologies, this invention has the following advantages and technical effects: This invention discloses a quantitative drug feeding device for mouse experiments. The main body is designed in a gun shape, conforming to ergonomics, with a compact structure, making it easy for experimental personnel to hold and operate. The entire process of drug quantitativeization, transfer, and feeding can be completed with one hand, improving experimental efficiency, especially suitable for batch mouse experiments. The drug storage bottle is connected to the metering cylinder through a connecting component, and the sealing component is drivenly connected to the connecting component, so that the sealing of the drug storage bottle is automatically released when the connecting component is opened, simplifying the operation process, reducing the risk of drug exposure, and preventing drug leakage or contamination, ensuring a safe experimental environment. Through the sliding cooperation between the metering cylinder and the piston, combined with the precise control of the piston position by the adjustment component, the quantitative adjustment of the drug volume is achieved, ensuring that the amount of drug fed each time is accurate and controllable, avoiding human operation errors, and improving the reliability and repeatability of experimental data. The adjustment component is drivenly connected to the piston, supporting the adjustment of the piston position according to experimental needs, thereby changing the volume of the metering cylinder to adapt to different dosage requirements, enhancing the versatility and experimental flexibility of the device. When not in use, the sealing assembly seals the drug storage bottle. Combined with the independent structure of the metering cylinder, this prevents drug backflow or external contamination, reducing the risk of errors caused by drug contamination during experiments and ensuring the health of the mice and the accuracy of experimental results. During operation, the connecting assembly is activated by a trigger on the main unit. This assembly drives the piston to administer the drug in precise doses, while simultaneously opening the sealing assembly to replenish the metering cylinder, facilitating the next administration and enabling continuous drug delivery.

[0020] This invention features a compact structure and convenient operation, allowing for flexible and easy drug feeding to mice, thus improving experimental accuracy. Simultaneously, it enables continuous replenishment of the drug solution during administration, thereby achieving continuous operation, reducing workload, and minimizing the risk of drug contamination. Attached Figure Description

[0021] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the embodiments will be briefly described below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. In the drawings:

[0022] Figure 1 This is an axial view of the drug quantitative feeding device for mouse experiments of the present invention;

[0023] Figure 2 This is a schematic diagram of the structure of the quantitative drug feeding device for mouse experiments of the present invention;

[0024] Figure 3 For the present invention Figure 2 A magnified view of part A in the image;

[0025] Figure 4 For the present invention Figure 2 A magnified view of part B in the image;

[0026] Figure 5 For the present invention Figure 2 A magnified view of part C;

[0027] Figure 6 For the present invention Figure 2 A magnified view of part D;

[0028] Figure 7 For the present invention Figure 2 A magnified view of part E in the image;

[0029] Figure 8 This is a schematic diagram of the adjustment component structure of the present invention;

[0030] In the diagram: 1. Main body; 2. Medicine storage bottle; 3. Metering cylinder; 4. Feeding tube; 11. Piston rod; 12. Feeding trigger; 13. Force ring; 14. Transfer chamber; 15. Replenishment channel; 16. Drive block; 17. Connecting block; 18. Drive rod; 19. Transfer channel; 110. Fixing knob; 111. First clearance chamber; 112. First clearance rod; 113. First clearance spring; 21. Sealing block; 22. Positioning tube; 23. Elastic block; 24. Hinge rod; 25. Sealing rod; 26. Sealing plug; 27. Medicine outlet; 28. Stirring shaft; 29. ​​Stirring rod; 210. 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 210, 210, 212, 213, 214, 215, 216, 217, 218, 219 ... Detailed Implementation

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0033] Reference Figures 1 to 8 As shown, this embodiment provides a quantitative feeding device for mice, including a gun-shaped main body 1, a drug storage bottle 2 for storing drug solution on the main body 1, the drug storage bottle 2 is connected to a quantitative cylinder 3 at the end of the main body 1 through a connecting component, and the quantitative cylinder 3 is connected to a feeding tube 4 for feeding drugs to mice.

[0034] The medicine storage bottle 2 is equipped with a sealing component for sealing. The sealing component is connected to the connecting component. The connecting component opens the sealing component, allowing the medicine liquid in the medicine storage bottle 2 to enter the metering cylinder 3.

[0035] A piston 32, which is connected to the communication component, is slidably disposed in the metering cylinder 3. The piston 32 feeds the drug solution to the mice through the feeding tube 4.

[0036] The end of the metering cylinder 3 is provided with an adjustment component corresponding to the piston 32. The adjustment component is connected to the piston 32 in a transmission manner to adjust the position of the piston 32.

[0037] This invention discloses a quantitative drug feeding device for mouse experiments. The main body 1 is designed in a gun shape, conforming to ergonomics, with a compact structure, making it easy for experimenters to hold and operate. The entire process of drug dosage, transfer, and feeding can be completed with one hand, improving experimental efficiency, especially suitable for batch mouse experiments. The drug storage bottle 2 is connected to the metering cylinder 3 via a connecting component. The sealing component is drivenly connected to the connecting component, so that the sealing of the drug storage bottle 2 is automatically released when the connecting component is opened, simplifying the operation process, reducing the risk of drug exposure, and preventing drug leakage or contamination, ensuring a safe experimental environment. Through the sliding cooperation between the metering cylinder 3 and the piston 32, combined with the precise control of the piston 32 position by the adjustment component, the dosage of drug fed per feeding can be changed, ensuring that the amount of drug fed each time is accurate and controllable, increasing the versatility and flexibility of the device, avoiding human operation errors, meeting the requirements of drug dosage in mouse experiments, and improving the reliability and repeatability of experimental data. The adjustment component is drivenly connected to the piston 32, supporting the adjustment of the piston 32 position according to experimental needs, thereby changing the volume of the metering cylinder 3 to adapt to different dosage requirements, enhancing the versatility and experimental flexibility of the device. When not in use, the sealing assembly seals the drug storage bottle 2. Combined with the independent structure of the metering cylinder 3, this prevents drug backflow or external contamination, reducing the risk of errors caused by drug contamination during experiments and ensuring the health of the mice and the accuracy of experimental results. During operation, the connecting assembly is activated by a trigger on the main body 1. This connecting assembly drives the piston 32 to administer the drug in a metering manner. Simultaneously, the connecting assembly opens the sealing assembly, replenishing the metering cylinder 3 for subsequent administration, facilitating continuous drug delivery. This invention features a compact structure and convenient operation, allowing for flexible and convenient drug feeding to mice, improving experimental accuracy. Furthermore, it enables continuous drug replenishment during administration, allowing for continuous operation, reducing workload, and minimizing the risk of drug contamination.

[0038] In one embodiment of the present invention, the handle of the main body 1 is provided with anti-slip texture to improve the comfort of operation.

[0039] In one embodiment of the present invention, a flexible feeding ball 41 is provided at the end of the feeding tube 4 to prevent the end of the feeding tube 4 from injuring the mouse during administration, thereby improving safety.

[0040] In one embodiment of the present invention, the feeding ball 41 is provided with a plurality of feeding holes 42 for convenient drug administration.

[0041] Further optimization of the design includes a piston 32 comprising a fixed plate 33 connected to the communicating component for transmission. Several rotating rods 34 rotate synchronously on the fixed plate 33. These rotating rods 34 are threadedly connected to a movable plate 35 slidably connected within the metering cylinder 3. A flexible plug 37 is fixedly attached to the end of the movable plate 35 furthest from the fixed plate 33. A threaded cylinder 36, corresponding to the rotating rods 34, is provided on the movable plate 35. Rotating the rotating rods 34 allows for fine-tuning of the positions of the movable plate 35 and the plug 37, thereby adjusting the initial drug volume in the metering cylinder 3, improving the accuracy of drug dispensing, and adapting to the need for fine adjustments to different dosages. The flexible plug 37 better conforms to the inner wall of the metering cylinder 3, reducing leakage of the drug during the feeding process, ensuring that the actual feeding dosage matches the set dosage, and improving the accuracy of experimental data.

[0042] The scheme is further optimized. The adjustment component includes an adjustment rod 38 rotatably connected to the metering cylinder 3. A drive gear 39 is drivenly connected to the adjustment rod 38. The drive gear 39 meshes with a driven gear 310 rotatably connected to the fixed plate 33. A rotating rod 34 extends into the fixed plate 33 and is drivenly connected to the driven gear 310. When adjusting the dosage, the adjustment rod 38 drives the drive gear 39 to rotate, which in turn drives the rotating rod 34 to rotate through the driven gear 310 meshing with the drive gear 39. This, in turn, pushes the movable plate 35 to slide in the metering cylinder 3, adjusting the position of the soft stopper 37, and thus adjusting the dosage. The operation is simple and the adjustment process is stable, avoiding the inconvenience and errors caused by manually adjusting the rotating rod 34 directly.

[0043] In one embodiment of the present invention, the transmission ratio between the driving gear 39 and the driven gear 310 can be selected as needed to further improve the adjustment accuracy.

[0044] Further optimization of the design involves a feeding chamber 31 within the metering cylinder 3. A piston 32 is slidably and sealed within the feeding chamber 31, pressing the medication from the feeding chamber 31 into the medication tube 4 through the medication outlet channel 311. A reset chamber 312 is located at the end of the feeding chamber 31 furthest from the connecting component, and a reset spring 313 is installed between the reset chamber 312 and the piston 32. The feeding chamber 31 provides an independent space for the quantitative storage of the medication. Combined with the sealed sliding of the piston 32, this reduces contact between the medication and other components of the device, lowering the risk of medication contamination. The reset spring 313 automatically resets the piston 32 after it has pushed the medication, preparing it for the next medication intake and push, eliminating the need for manual reset, improving feeding efficiency, and ensuring the consistency of the piston 32's reset position each time, indirectly improving the accuracy of the medication dosage.

[0045] In one embodiment of the present invention, a transparent scale 314 is provided on the side wall of the feeding cavity 31 to facilitate the positioning of the drug dosage.

[0046] Further optimization of the design includes a connecting component comprising a piston rod 11 slidably connected within the main body 1. The piston rod 11 extends into the feeding chamber 31 and is drivenly connected to the piston 32. The piston rod 11 is also drivenly connected to a feeding trigger 12 mounted on the main body 1. Pulling the feeding trigger 12 moves the piston 32 within the feeding chamber 31. This trigger-type transmission structure simulates firearm operation, providing rapid response and timely completion of the feeding action. This aligns with the operating habits of experimental personnel, reducing the learning curve and making the feeding action more convenient and efficient. Furthermore, the stability of the trigger operation reduces the impact of human error on the dosage. By pulling the feeding trigger 12, the piston rod 11 moves, which in turn drives the piston 32, thus achieving drug administration. The operation is simple and convenient.

[0047] In one embodiment of the present invention, a clearance structure is provided in the middle of the piston rod 11, which mainly consists of a first clearance cavity 111 and a first clearance rod 112 elastically connected by a first clearance spring 113, providing movement space for the piston rod 11.

[0048] In one embodiment of the present invention, the end of the piston rod 11 away from the piston 32 is installed via a fixing knob 110 for convenient subsequent maintenance.

[0049] Further optimization of the design includes a transfer chamber 14 within the main body 1. The transfer chamber 14 is connected to the feeding chamber 31 via a replenishment channel 15 located on the piston rod 11. The transfer chamber 14 is also connected to the sealing assembly. Medication from the storage bottle 2 is injected into the feeding chamber 31 through the transfer chamber 14 and the replenishment channel 15. The transfer chamber 14 serves as a transition space for the medication from the storage bottle 2 to the feeding chamber 31, buffering and temporarily storing the medication to prevent instability in dosage due to pressure fluctuations when the medication from the storage bottle 2 directly enters the feeding chamber 31. The replenishment channel 15, located on the piston rod 11, links medication replenishment to the movement of the piston 32, allowing for simultaneous medication replenishment during piston 32 reset without additional steps, thus improving the automation level and feeding efficiency of the device.

[0050] In a further optimized design, a drive block 16, fixedly connected to the piston rod 11, is slidably connected within the transfer chamber 14. A connecting block 17 is slidably connected to the inclined side of the drive block 16, and a drive rod 18 is hinged to the connecting block 17. The drive rod 18 is arranged along the transfer channel 19, which communicates with the transfer chamber 14, and is connected to the sealing assembly via a transmission mechanism. By utilizing the sliding engagement between the inclined side of the drive block 16 and the connecting block 17, the linear motion of the piston rod 11 is converted into the linear motion of the drive rod 18, achieving efficient power transmission. This design is compact, occupies little internal space, and facilitates the overall miniaturization of the device. Initially, the connecting block 17 is at the lower end of the inclined side of the drive block 16. When the piston rod 11 moves the drive block 16, the inclined side pushes the drive rod 18 towards the sealing assembly, opening the sealing assembly and allowing the liquid medicine to be smoothly transferred from the medicine storage bottle 2 to the feeding chamber 31, ensuring continuous feeding.

[0051] The design is further optimized. The sealing component includes a sealing block 21 that slides at the mouth of the drug storage bottle 2. A sealing module for controlling drug discharge is located at the end of the sealing block 21 furthest from the drug storage bottle 2. After the drug storage bottle 2 is installed, the transfer channel 19 opens the sealing block 21. The drive rod 18 is connected to the sealing module, and when the drive rod 18 moves, it opens the sealing module, allowing the drug to enter the transfer channel 19. When the drug storage bottle 2 is not installed on the main body 1, the sealing block 21 automatically closes the bottle mouth under elastic pressure, preventing the drug from contacting the outside environment, allowing for simultaneous drug preparation and administration to multiple mice. When the drug storage bottle 2 is installed on the main body 1, the transfer channel 19 opens the sealing block 21, achieving initial connection preparation between the drug storage bottle 2 and the device. The opening of the sealing module relies on the movement of the drive rod 18, forming a dual control system to prevent uncontrolled leakage of the drug after the drug storage bottle 2 is installed, thus improving the safety of the device. The sealing module can precisely control the timing and rate of liquid discharge. In conjunction with the linkage between the drive rod 18 and the piston rod 11, it ensures that the sealing module only opens when the piston 32 resets and needs to be replenished with liquid, further ensuring the accuracy of liquid dispensing.

[0052] Further optimization of the design includes a sealing module comprising a positioning tube 22 fixed to a sealing block 21. An elastic block 23, which is flexibly connected to a drive rod 18, slides within the positioning tube 22. Several sealing rods 25 are connected to the elastic block 23. Each sealing rod 25 extends out of the positioning tube 22 and is fixedly connected to a flexibly configured sealing plug 26. The sealing plug 26 is detachably connected to a medicine outlet 27 located on the sealing block 21. (See appendix) Figure 5As shown, the elastic sliding design of the elastic block 23 provides a buffer for the opening action of the sealing module by the drive rod 18, preventing damage to components due to rigid contact. Simultaneously, when the drive rod 18 resets, the elastic block 23 can automatically reset the sealing rod 25 and the sealing plug 26, achieving automatic sealing of the dispensing hole 27 and further preventing leakage of the medicine. During operation, when the drive rod 18 moves under the drive of the piston rod 11, it pushes the elastic block 23 to move. As the elastic block 23 moves, the angle of the hinge rod 24, hinged between the elastic block 23 and the sealing rod 25, changes, causing the sealing rod 25 to move and remove the sealing plug 26 from the dispensing hole 27, allowing the medicine in the storage bottle 2 to flow from the dispensing port into the transfer channel 19, and then into the transfer chamber 14. After the medication is administered, the drive block 16 moves back, causing the drive rod 18 to reset. The elastic block 23 automatically resets, causing the sealing rod to push the sealing plug to seal the drug outlet 27 again, thus isolating the drug storage bottle 2 from the outside world once more.

[0053] Further optimization involves incorporating a stirring shaft 28 within the drug storage bottle 2. This shaft 28 is rotatably connected between the sealing block 21 and the bottom of the bottle. Several stirring rods 29 are fixed to the outer wall of the stirring shaft 28. The stirring shaft 28 is also connected to a drive rod 18. Simultaneously, the drive rod 18 opens the sealing module and drives the stirring shaft 28 and stirring rods 29 to rotate, achieving simultaneous stirring and discharge of the drug solution. This prevents sedimentation and stratification due to settling, ensuring uniform drug concentration and consistent drug composition for each feeding to mice, thus improving the reliability of experimental data. No additional stirring power source is required; the stirring function is achieved using the device's own transmission structure, simplifying the device structure, reducing costs, and minimizing energy consumption and malfunction risks.

[0054] In one embodiment of the present invention, a second clearance hole is provided at the end of the stirring rod 29 away from the sealing block. A second clearance rod 211 is elastically connected to the second clearance hole through a second clearance spring 212. The second clearance rod 211 extends out of the second clearance hole and is rotatably connected to the bottom of the inner cavity of the medicine storage bottle 2, so that the stirring shaft 28 has extensibility and will not affect the operation of the stirring shaft 28 when the sealing block is pushed open.

[0055] In one embodiment of the present invention, a fixing seat 213 is provided at one end of the sealing block 21 located inside the medicine storage bottle 2, and the stirring shaft 28 is sealed and rotated on the fixing seat 213, which facilitates the installation of the stirring shaft 28.

[0056] In one embodiment of the present invention, a third clearance cavity 214 is provided at the bottom end of the stirring shaft 28. A rotating disk 217 is installed in the third clearance cavity 214 via a third clearance spring 216. A third clearance rod 215 is rotatably connected to one end of the rotating disk 217 away from the third clearance spring 216. The third clearance rod 215 is threadedly connected to the third clearance cavity 214 and extends out of the third clearance cavity 214. The third clearance rod 215 is fixedly connected to the elastic block 23. When the elastic block 23 moves under the push of the drive rod 18, it drives the third clearance rod 215 to move, thereby driving the stirring shaft 28 to rotate. In actual use, the third clearance rod 215 reciprocates under the drive of the drive rod 18, thereby driving the stirring shaft 28 to rotate.

[0057] In the description of this invention, it should be understood that the terms "longitudinal", "lateral", "up", "down", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this invention, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0058] The embodiments described above are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Various modifications and improvements made by those skilled in the art to the technical solutions of the present invention without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.

Claims

1. A quantitative feeding device for drugs in mouse experiments, characterized in that: The main body (1) includes a gun-shaped structure. A medicine storage bottle (2) for storing medicine is provided on the main body (1). The medicine storage bottle (2) is connected to a metering cylinder (3) at the end of the main body (1) through a connecting component. The metering cylinder (3) is connected to a feeding tube (4) for feeding medicine to mice. The medicine storage bottle (2) is provided with a sealing assembly for sealing. The sealing assembly is connected to the communication assembly. The communication assembly opens the sealing assembly, allowing the medicine in the medicine storage bottle (2) to enter the metering cylinder (3). A piston (32) that is slidably connected to the communication component is provided in the metering cylinder (3). The piston (32) feeds the drug solution to the mice through the feeding tube (4). The end of the metering cylinder (3) is provided with an adjustment component corresponding to the piston (32). The adjustment component is connected to the piston (32) in a transmission manner to adjust the position of the piston (32).

2. The quantitative feeding device for drugs used in mouse experiments according to claim 1, characterized in that: The piston (32) includes a fixed plate (33) that is pulsatorically connected to the communicating component. Several rotating rods (34) are synchronously rotated on the fixed plate (33). The several rotating rods (34) are threadedly connected to a movable plate (35) that is slidably connected in the metering cylinder (3). A flexible plug (37) is fixedly connected to one end of the movable plate (35) away from the fixed plate (33).

3. The quantitative feeding device for drugs used in mouse experiments according to claim 2, characterized in that: The adjusting assembly includes an adjusting rod (38) rotatably connected to the metering cylinder (3), a driving gear (39) is drivenly connected to the adjusting rod (38), the driving gear (39) meshes with a driven gear (310) rotatably connected in the fixed plate (33), and the rotating rod (34) extends into the fixed plate (33) and is drivenly connected to the driven gear (310).

4. The quantitative feeding device for drugs used in mouse experiments according to claim 1, characterized in that: The metering cylinder (3) has a feeding chamber (31) inside, and the piston (32) is sealed and slidably connected in the feeding chamber (31) to press the liquid medicine in the feeding chamber (31) into the feeding tube (4) through the medicine outlet channel (311); a reset chamber (312) is provided at the end of the feeding chamber (31) away from the connecting component, and a reset spring (313) is provided between the reset chamber (312) and the piston (32).

5. The quantitative feeding device for drugs used in mouse experiments according to claim 4, characterized in that: The communication component includes a piston rod (11) slidably connected within the main body (1), the piston rod (11) extending into the feeding chamber (31) and being throttledly connected to the piston (32), the piston rod (11) being throttledly connected to a feeding trigger (12) mounted on the main body (1), and pulling the feeding trigger (12) causing the piston (32) to move within the feeding chamber (31).

6. The quantitative feeding device for drugs used in mouse experiments according to claim 5, characterized in that: The communication assembly also includes a transfer chamber (14) opened in the main body (1). The transfer chamber (14) is connected to the feeding chamber (31) through a drug replenishment channel (15) provided on the piston rod (11). The transfer chamber (14) is connected to the sealing assembly. The medicine in the medicine storage bottle (2) is injected into the feeding chamber (31) through the transfer chamber (14) and the drug replenishment channel (15).

7. The quantitative feeding device for drugs used in mouse experiments according to claim 6, characterized in that: The transfer cavity (14) is slidably connected to a drive block (16) which is fixed to the piston rod (11). A connecting block (17) is slidably connected to the inclined side of the drive block (16). A drive rod (18) is hinged to the connecting block (17). The drive rod (18) is arranged along the transfer channel (19) which communicates with the transfer cavity (14) and is connected to the sealing assembly in a transmission manner.

8. The quantitative feeding device for drugs in mouse experiments according to claim 7, characterized in that: The sealing assembly includes a sealing block (21) that is slidably disposed at the mouth of the medicine storage bottle (2). The end of the sealing block (21) away from the medicine storage bottle (2) is provided with a sealing module for controlling the discharge of the medicine liquid. After the medicine storage bottle (2) is installed, the transfer channel (19) pushes open the sealing block (21). The drive rod (18) is connected to the sealing module. When the drive rod (18) moves, it pushes open the sealing module, allowing the medicine liquid to enter the transfer channel (19).

9. The quantitative feeding device for drugs used in mouse experiments according to claim 8, characterized in that: The sealing module includes a positioning tube (22) fixed to the sealing block (21). An elastic block (23) that is flexibly connected to the driving rod (18) slides inside the positioning tube (22). A plurality of sealing rods (25) are flexibly connected to the elastic block (23). The sealing rods (25) extend out of the positioning tube (22) and are fixed with a flexibly provided sealing plug (26). The sealing plug (26) is detachably connected to the medicine outlet hole (27) opened on the sealing block (21).

10. The quantitative feeding device for drugs in mouse experiments according to claim 8, characterized in that: The medicine storage bottle (2) is provided with a stirring shaft (28), which is rotatably connected between the sealing block (21) and the bottom of the medicine storage bottle (2). Several stirring rods (29) are fixed to the outer wall of the stirring shaft (28). The stirring shaft (28) is connected to the driving rod (18) in a transmission connection.