Powder decoction plaster for treatment and health care of rheumatism bone diseases and preparation method of powder decoction plaster

Abstract

The invention belongs to the technical field of traditional Chinese medicine compositions, and provides a powder decoction plaster for treatment and health care of rheumatism bone diseases and a preparation method thereof, the powder decoction plaster comprises the following raw materials by mass: 20-25 parts of ox horn slices, 10-25 parts of light wheat, 20-25 parts of yellow ginger, 20-25 parts of dried ginger, 2-10 parts of notopterygium root, 3-10 parts of sichuanese peppercorn, 0.1-0.5 part of safflower, 0.1-2 parts of cortex acanthopanacis, 0.1-0.5 part of licorice, 1-5 parts of rhizoma cibotii, and 1-5 parts of cortex dictamni. The traditional Chinese medicine disclosed by the invention is decocted into ointment to be applied to an affected part, has the effects of promoting rehabilitation and health, and is used for treatment and health care of lumbar disc herniation, cervical spondylosis, fracture, arthritis, synovitis, hyperostosis, scapulohumeral periarthritis, lumbar disc herniation, sprain and contusion and soft tissue contusion.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine composition technology, and in particular to a powder-based ointment for the treatment and health care of rheumatic bone diseases and its preparation method. Background Technology

[0002] Rheumatic bone diseases are a group of illnesses characterized by pain, swelling, and functional impairment in the joints, muscles, bones, and soft tissues. These include conditions such as lumbar disc herniation, cervical spondylosis, arthritis, synovitis, and bone hyperplasia, severely impacting patients' quality of life. Currently, commonly used clinical treatments include oral medications and topical ointments, with topical ointments being widely used due to their direct application to the affected area and minimal side effects.

[0003] However, existing topical plasters and powders for rheumatic bone diseases have shortcomings in their formulation and preparation process: on the one hand, the proportions of the ingredients in the formulation are unreasonable, resulting in unstable efficacy; on the other hand, the preparation process is complex and the overall preparation efficiency is low, making it difficult to meet the needs of large-scale production and clinical application.

[0004] Therefore, developing a scientifically formulated, highly efficient, and effective decoction powder for the treatment and health maintenance of rheumatic bone diseases is of great clinical significance and application value. Summary of the Invention

[0005] In view of the shortcomings of existing external powder formulations for rheumatic bone diseases, such as unreasonable formulations and low preparation efficiency, this invention provides a decoction powder formulation and preparation method for the treatment and health care of rheumatic bone diseases, so as to improve preparation efficiency and optimize efficacy.

[0006] To achieve the above objectives, this invention provides a powder-based ointment for the treatment and health maintenance of rheumatic bone diseases, and its preparation method, comprising the following raw materials in parts by weight: 20-25 parts of ox horn slices, 10-25 parts of floating wheat, 20-25 parts of turmeric, 20-25 parts of dried ginger, 2-10 parts of Notopterygium root, 3-10 parts of Sichuan pepper, 0.1-0.5 parts of safflower, 0.1-2 parts of Acanthopanax bark, 0.1-0.5 parts of licorice root, 1-5 parts of Cibotium barometz, and 1-5 parts of Dictamnus dasycarpus root bark.

[0007] As a preferred embodiment, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 20 parts of ox horn slices, 10 parts of floating wheat, 20 parts of yellow ginger, 20 parts of dried ginger, 2 parts of notopterygium root, 3 parts of Sichuan pepper, 0.1 part of safflower, 0.1 part of eleutherococcus senticosus bark, 0.1 part of licorice root, 1 part of cibotium barometz, and 1 part of dictamnus dasycarpus bark.

[0008] As a preferred embodiment, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 15 parts of ox horn slices, 15 parts of floating wheat, 16 parts of yellow ginger, 21 parts of dried ginger, 6 parts of notopterygium root, 5 parts of Sichuan pepper, 0.3 parts of safflower, 1 part of Acanthopanax bark, 0.2 parts of licorice root, 2 parts of Cibotium barometz, and 3 parts of Dictamnus dasycarpus root bark.

[0009] As a preferred embodiment, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 25 parts of ox horn slices, 25 parts of floating wheat, 25 parts of yellow ginger, 25 parts of dried ginger, 10 parts of notopterygium root, 10 parts of Sichuan pepper, 0.5 parts of safflower, 2 parts of eleutherococcus senticosus bark, 0.5 parts of licorice root, 5 parts of Cibotium barometz, and 5 parts of Dictamnus dasycarpus bark.

[0010] This invention also provides a method for preparing a powder-based ointment for the treatment and health maintenance of rheumatic bone diseases, comprising the following steps:

[0011] (1) Remove the husks from the floating wheat and grind it to obtain floating wheat flour;

[0012] (2) Mix and grind the ox horn slices, yellow ginger, dried ginger, notopterygium root, Sichuan pepper, safflower, eleutherococcus senticosus bark, licorice, cibotium barometz and dictamnus root bark, and pass through a 200-mesh sieve to obtain a mixture;

[0013] (3) Mix the floating wheat flour, wheat flour and the mixing agent to obtain the powder;

[0014] (4) Mix vinegar and water in a certain ratio, then add the powder, boil it down, and spread it on a white cloth to obtain the powder-based ointment for the treatment and health care of rheumatic bone diseases.

[0015] Preferably, the particle size sieved in step (1) is 200 mesh.

[0016] Preferably, the ratio of vinegar, water and powder is 30mL:70mL:25-30g.

[0017] Preferably, the heating temperature in step (4) is 60 to 100°C.

[0018] Preferably, the cooking temperature in step (4) is 60-100°C.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] The components work synergistically, possessing the effects of dispelling wind and dampness, promoting blood circulation and relieving pain, and strengthening muscles and bones. It has significant therapeutic effects on rheumatic bone diseases such as lumbar disc herniation, cervical spondylosis, and arthritis, while also having health-preserving effects. Through group synthesis, floating wheat is ground into powder separately, while other components are mixed and pulverized, avoiding the "burning" problem during mixing and grinding, shortening the preparation time, and improving production efficiency. The particle size and cooking parameters are clearly defined to ensure stable product quality and suitability for large-scale production. After being cooked into a paste, it can be directly applied to the affected area, making it easy to use and resulting in high patient compliance. Detailed Implementation

[0021] This invention provides a powder-based ointment for the treatment and health maintenance of rheumatic bone diseases, comprising the following raw materials in parts by weight: 20-25 parts of ox horn slices, 10-25 parts of floating wheat, 20-25 parts of turmeric, 20-25 parts of dried ginger, 2-10 parts of Notopterygium root, 3-10 parts of Sichuan pepper, 0.1-0.5 parts of safflower, 0.1-2 parts of Acanthopanax bark, 0.1-0.5 parts of licorice root, 1-5 parts of Cibotium barometz, and 1-5 parts of Dictamnus dasycarpus root bark.

[0022] In this invention, the powder-based ointment contains 20-25 parts of ox horn slices, preferably 21-24 parts, more preferably 22-23 parts, and even more preferably 22.5 parts.

[0023] In this invention, the powder-based ointment contains 10-25 parts of floating wheat, preferably 11-24 parts, more preferably 12-23 parts, and even more preferably 13-24 parts.

[0024] In this invention, the powder-based ointment contains 20-25 parts of turmeric, preferably 21-24 parts, more preferably 22-23 parts, and even more preferably 15-18 parts.

[0025] In this invention, the powder-based ointment contains 20-25 parts of dried ginger, preferably 21-24 parts, more preferably 22-23 parts, and even more preferably 15-18 parts.

[0026] In this invention, the powder-based ointment contains 2 to 10 parts of Notopterygium root, preferably 3 to 9 parts, more preferably 4 to 8 parts, and even more preferably 5 to 6 parts.

[0027] In this invention, the powder-based ointment contains 3 to 10 parts of Sichuan pepper, preferably 4 to 9 parts, more preferably 5 to 8 parts, and even more preferably 6 to 8 parts.

[0028] In this invention, the powder-based ointment contains 0.1 to 0.5 parts of safflower, preferably 0.25 to 0.43 parts, more preferably 0.3 to 0.4 parts, and even more preferably 0.35 to 0.38 parts.

[0029] In this invention, the powder-based ointment contains 0.1 to 2 parts of Acanthopanax senticosus root bark, preferably 0.14 to 0.19 parts, more preferably 0.15 to 0.18 parts, and even more preferably 0.16 to 0.17 parts.

[0030] In this invention, the powder-to-plaster formula contains 0.1 to 0.5 parts of licorice, preferably 0.14 to 0.49 parts, more preferably 0.2 to 0.4 parts, and even more preferably 0.25 to 0.3 parts.

[0031] In this invention, the powder-based ointment contains 1 to 5 parts of Cibotium barometz, preferably 0.12 to 0.45 parts, more preferably 0.15 to 0.35 parts, and even more preferably 0.26 to 0.3 parts.

[0032] In this invention, the powder-based ointment contains 1 to 5 parts of Dictamnus dasycarpus root bark, preferably 0.17 to 0.46 parts, more preferably 0.29 to 0.4 parts, and even more preferably 0.36 to 0.39 parts.

[0033] In this invention, the ox horn slices have the functions of clearing heat and detoxifying, cooling blood and stopping bleeding, calming the mind and relieving convulsions, promoting blood circulation and removing blood stasis, and reducing swelling.

[0034] In this invention, the floating wheat is used to strengthen the exterior and stop sweating, treat bone steaming fever, and replenish qi.

[0035] In this invention, the turmeric is used for rheumatic back pain and traumatic injuries.

[0036] In this invention, the dried ginger warms the middle jiao, dispels cold, and eliminates wind and dampness.

[0037] In this invention, the notopterygium root has the functions of relieving exterior syndromes, dispelling cold, eliminating wind and dampness, and relieving pain.

[0038] In this invention, the Sichuan peppercorns are used to warm the middle burner, relieve pain, dispel cold, and eliminate dampness.

[0039] In this invention, safflower is used to promote blood circulation, regulate menstruation, disperse blood stasis, and relieve pain.

[0040] In this invention, Acanthopanax senticosus has the functions of dispelling wind and dampness, strengthening muscles and bones, and promoting diuresis and reducing swelling.

[0041] In this invention, the licorice has the functions of relieving pain, clearing heat and detoxifying.

[0042] In this invention, the Cibotium barometz is used to dispel wind and dampness, tonify the liver and kidneys, and strengthen the waist and knees.

[0043] In this invention, the white peony root bark is used to dispel wind and detoxify.

[0044] In this invention, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 20 parts of ox horn slices, 10 parts of floating wheat, 20 parts of turmeric, 20 parts of dried ginger, 2 parts of notopterygium root, 3 parts of Sichuan pepper, 0.1 part of safflower, 0.1 part of eleutherococcus senticosus bark, 0.1 part of licorice root, 1 part of Cibotium barometz, and 1 part of Dictamnus dasycarpus bark.

[0045] In this invention, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 15 parts of ox horn slices, 15 parts of floating wheat, 16 parts of turmeric, 21 parts of dried ginger, 6 parts of notopterygium root, 5 parts of Sichuan pepper, 0.3 parts of safflower, 1 part of eleutherococcus senticosus bark, 0.2 parts of licorice root, 2 parts of cibotium barometz, and 3 parts of dictamnus dasycarpus bark.

[0046] In this invention, the powder-based ointment for the treatment and health care of rheumatic bone diseases comprises the following raw materials in parts by weight: 25 parts of ox horn slices, 25 parts of floating wheat, 25 parts of yellow ginger, 25 parts of dried ginger, 10 parts of notopterygium root, 10 parts of Sichuan pepper, 0.5 parts of safflower, 2 parts of Acanthopanax bark, 0.5 parts of licorice root, 5 parts of Cibotium barometz, and 5 parts of Dictamnus dasycarpus root bark.

[0047] This invention also provides a method for preparing a powder-based ointment for the treatment and health maintenance of rheumatic bone diseases, comprising the following steps:

[0048] (1) Remove the husks from the floating wheat and grind it to obtain floating wheat flour;

[0049] (2) Mix and grind the ox horn slices, yellow ginger, dried ginger, notopterygium root, Sichuan pepper, safflower, eleutherococcus senticosus bark, licorice, cibotium barometz and dictamnus root bark, and pass through a 200-mesh sieve to obtain a mixture;

[0050] (3) Mix the floating wheat flour, wheat flour and the mixing agent to obtain the powder;

[0051] (4) Mix vinegar and water in a certain ratio, then add the powder, boil it down, and spread it on a white cloth to obtain the powder-based ointment for the treatment and health care of rheumatic bone diseases.

[0052] In this invention, the particle size sieved in step (1) is 200 mesh.

[0053] In this invention, the ratio of vinegar, water and powder is 30mL:70mL:25-30g, preferably 30mL:70mL:2-29g, more preferably 30mL:70mL:27-28g, and even more preferably 30mL:70mL:27.5-27.8g.

[0054] In this invention, the heating temperature in step (4) is 60-100°C, preferably 5-95°C, more preferably 70-80°C, and even more preferably 72-78°C.

[0055] In this invention, the cooking temperature in step (4) is 60-100°C, preferably 5-95°C, more preferably 70-80°C, and even more preferably 72-78°C.

[0056] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0057] Example 1

[0058] Peel and grind 10g of floating wheat, then sift it through a 200-mesh sieve and set aside. Mix 20g of horn slices, 20g of turmeric, 20g of dried ginger, 2g of notopterygium root, 3g of Sichuan pepper, 0.1g of safflower, 0.1g of eleutherococcus senticosus root bark, 0.1g of licorice root, 1g of Cibotium barometz, and 1g of Dictamnus dasycarpus root bark in the specified proportions, grind them, and sift them through a 200-mesh sieve to obtain a mixture. Combine the floating wheat powder, the mixture, and 15g of wheat flour together, stir well, and package and store as a powder.

[0059] Mix 85mL of vinegar with 200mL of water and heat to 100℃ until boiling. Pour the powder and vinegar-water mixture into an aluminum or stainless steel container and simmer together at 100℃ until it becomes a paste. Spread the paste on a white cloth and apply it to the affected area. This gives you a powder-based plaster for the treatment and health care of rheumatic bone diseases.

[0060] Example 2

[0061] Peel and grind 15g of floating wheat, then sift it through a 200-mesh sieve and set aside. Mix 15g of horn slices, 16g of turmeric, 21g of dried ginger, 6g of notopterygium root, 5g of Sichuan pepper, 0.3g of safflower, 1g of eleutherococcus senticosus root bark, 0.2g of licorice root, 2g of Cibotium barometz, and 3g of Dictamnus dasycarpus root bark in the specified proportions, then sift them through a 200-mesh sieve to obtain a mixture. Combine the floating wheat powder, the mixture, and 20g of wheat flour together, stir well, and package as a powder for storage.

[0062] Mix 101mL of vinegar with 20mL of water and heat at 80℃. Pour the powder and vinegar-water mixture into an aluminum or stainless steel container and boil it together at 80℃ until it becomes a paste. Spread it on a white cloth and apply it to the affected area. This gives you a powder-based plaster for the treatment and health care of rheumatic bone diseases.

[0063] Example 3

[0064] Peel and grind 25g of floating wheat, then sift it through a 200-mesh sieve and set aside. Mix 25g of horn slices, 25g of turmeric, 25g of dried ginger, 10g of notopterygium root, 10g of Sichuan pepper, 0.5g of safflower, 2g of eleutherococcus senticosus root bark, 0.5g of licorice root, 5g of Cibotium barometz, and 5g of Dictamnus dasycarpus root bark in the specified proportions, grind them, and sift them through a 200-mesh sieve to obtain a mixture. Combine the floating wheat powder, the mixture, and 23g of wheat flour together, stir well, and package and store as a powder.

[0065] Mix 102mL of vinegar with 20mL of water and heat to 100℃ until boiling. Pour the powder and vinegar-water mixture into an aluminum or stainless steel container and simmer together at 100℃ until it becomes a paste. Spread the paste on a white cloth and apply it to the affected area. This gives you a powder-based plaster for the treatment and health care of rheumatic bone diseases.

[0066] Test case

[0067] Trial population: 120 patients were recruited clinically, including 60 males and 60 females, aged 18-65 years, all diagnosed with rheumatoid arthritis or osteoarthritis.

[0068] Test groups: Example 1, Example 2, Example 3 and reference example (a popular commercially available plaster for rheumatism and bone diseases);

[0069] Test groups: 30 patients were randomly assigned to each group;

[0070] Test content: Patients in each group applied the designated plaster on time every day, the treatment effect was recorded, and a follow-up visit was conducted one year after the cure to record whether there was a recurrence.

[0071]

[0072] As can be seen from the above embodiments, this invention is a formula comprising ox horn slices, floating wheat, turmeric, dried ginger, notopterygium root, Sichuan pepper, safflower, eleutherococcus senticosus bark, licorice root, cibotium barometz bark, and dictamnus root bark. First, the floating wheat is hulled and ground to obtain floating wheat flour. Then, it is ground into a fine powder with the raw material mixture in a certain proportion. The floating wheat flour, wheat flour, and the mixture are combined to obtain a powder. An appropriate amount of vinegar and water mixture is boiled and heated, and the powder is added to the mixture for further cooking. After being cooked into a paste, it is applied to the affected area. This invention, by applying the paste to the affected area, has the effect of promoting recovery and health, and is used for the treatment and health care of lumbar disc herniation, cervical spondylosis, fractures, arthritis, synovitis, bone hyperplasia, frozen shoulder, lumbar disc bulging, sprains, and soft tissue contusions.

[0073] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A powder-based ointment for the treatment and health maintenance of rheumatic bone diseases, characterized in that... The ingredients include the following parts by weight: 20-25 parts ox horn slices, 10-25 parts floating wheat, 20-25 parts yellow ginger, 20-25 parts dried ginger, 2-10 parts Notopterygium root, 3-10 parts Sichuan pepper, 0.1-0.5 parts safflower, 0.1-2 parts Acanthopanax bark, 0.1-0.5 parts licorice root, 1-5 parts Cibotium barometz, and 1-5 parts Dictamnus dasycarpus root bark.

2. The powder-based ointment for the treatment and health maintenance of rheumatic bone diseases according to claim 1, characterized in that, The ingredients include the following parts by weight: 20 parts ox horn slices, 10 parts floating wheat, 20 parts yellow ginger, 20 parts dried ginger, 2 parts Notopterygium root, 3 parts Sichuan pepper, 0.1 part safflower, 0.1 part Acanthopanax bark, 0.1 part licorice root, 1 part Cibotium barometz, and 1 part Dictamnus dasycarpus root bark.

3. The powder-based ointment for the treatment and health maintenance of rheumatic bone diseases according to claim 1, characterized in that, The ingredients include the following parts by weight: 15 parts ox horn slices, 15 parts floating wheat, 16 parts yellow ginger, 21 parts dried ginger, 6 parts Notopterygium root, 5 parts Sichuan pepper, 0.3 parts safflower, 1 part Acanthopanax bark, 0.2 parts licorice root, 2 parts Cibotium barometz, and 3 parts Dictamnus dasycarpus root bark.

4. The powder-based ointment for the treatment and health maintenance of rheumatic bone diseases according to claim 1, characterized in that, The ingredients include the following parts by weight: 25 parts ox horn slices, 25 parts floating wheat, 25 parts yellow ginger, 25 parts dried ginger, 10 parts Notopterygium root, 10 parts Sichuan pepper, 0.5 parts safflower, 2 parts Acanthopanax bark, 0.5 parts licorice root, 5 parts Cibotium barometz, and 5 parts Dictamnus dasycarpus root bark.

5. A method for preparing a powder-based ointment for the treatment and health maintenance of rheumatic bone diseases as described in claim 1, characterized in that, Includes the following steps: (1) Remove the husks from the floating wheat and grind it to obtain floating wheat flour; (2) Mix and grind the ox horn slices, yellow ginger, dried ginger, notopterygium root, Sichuan pepper, safflower, eleutherococcus senticosus bark, licorice, cibotium barometz and dictamnus root bark, and pass through a 200-mesh sieve to obtain a mixture; (3) Mix the floating wheat flour, wheat flour and the mixing agent to obtain the powder; (4) Mix vinegar and water in a certain ratio, then add the powder, boil it down, and spread it on a white cloth to obtain the powder-based ointment for the treatment and health care of rheumatic bone diseases.

6. The preparation method according to claim 5, characterized in that, The particle size sieved in step (1) is 200 mesh.

7. The preparation method according to claim 5, characterized in that, The ratio of vinegar, water, and powder is 30mL:70mL:25-30g.

8. The preparation method according to claim 5, characterized in that, The heating temperature in step (4) is 60-100℃.

9. The preparation method according to any one of claims 5 to 8, characterized in that, The cooking temperature in step (4) is 60-100℃.

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