Efficient plasma exchange type blood routine condensation collecting and processing device

Abstract

The invention relates to the technical field of medical separation equipment, and particularly discloses an efficient plasma exchange type blood routine condensation collection treatment device which comprises a machine body and a fixing plate, an extraction assembly is arranged on the outer side of the fixing plate, and the extraction assembly comprises a piston cylinder connected with the outer surface of the fixing plate in a clamped mode; a piston plate is slidably connected to the inner surface of the piston cylinder, a piston rod is fixedly connected to the outer surface of the upper end of the piston plate, a contact block is fixedly connected to the upper end of the piston rod, and a mounting sleeve is fixedly connected to the middle of the outer surface of the fixing plate. By arranging the extraction assembly, plasma in the test tube is sucked into the liquid suction tube under the action of gas pressure, so that the plasma can be separated from a cell layer, plasma separation and replacement treatment can be performed on multiple groups of blood samples at the same time, and the condensation and collection treatment speed of conventional blood samples can be effectively increased; and the sample treatment efficiency can be remarkably improved while the sample treatment precision is ensured.

Description

Technical Field

[0001] This invention relates to the field of medical separation equipment technology, and in particular to a high-efficiency plasma exchange-type blood routine cold agglomeration treatment device. Background Technology

[0002] During a routine blood test, red blood cells spontaneously aggregate in a low-temperature environment (<37℃), leading to a false decrease in red blood cell count, hemoglobin, and platelet count, which can adversely affect the results. Commonly used methods for cold agglutination treatment of blood include water bath rewarming, low-speed centrifugation, and plasma exchange.

[0003] Plasma exchange therapy utilizes a triple mechanism of physical plasma separation, temperature control, and washing with a replacement solution to separate and remove plasma from the blood and resuspend blood cells in a cold antibody-free replacement solution. This effectively removes cold antibodies and restores red blood cells to their normal state, thus ensuring the accuracy of routine blood test results. In practice, after centrifugation of the blood sample in a test tube, medical staff need to use a pipette to remove the upper plasma layer and inject an appropriate amount of cold antibody-free replacement solution. Extracting and separating plasma one by one during routine blood testing not only increases the workload of medical staff but also adversely affects the efficiency of cold agglutination processing in routine blood tests. Summary of the Invention

[0004] The purpose of this invention is to provide a high-efficiency plasma exchange-type blood routine cold agglomeration processing device, which can simultaneously perform plasma separation and exchange processing on multiple groups of blood samples, effectively improve the cold agglomeration processing speed of blood routine samples, and significantly improve sample processing efficiency while ensuring sample processing accuracy, thereby solving the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a high-efficiency plasma replacement type blood routine cold agglomeration processing device, comprising a body and a fixed plate, an extraction component disposed on the outer side of the fixed plate, the extraction component comprising a piston cylinder engaged with the outer surface of the fixed plate, a piston plate slidably connected to the inner surface of the piston cylinder, a piston rod fixedly connected to the upper outer surface of the piston plate, a contact block fixedly connected to the upper end of the piston rod, an installation sleeve fixedly connected to the middle of the outer surface of the fixed plate, a top rod rotatably connected to the inner surface of the installation sleeve, a movable plate fixedly connected to the upper outer surface of the top rod, a stop block fixedly connected to the lower outer surface of the movable plate, the lower outer surface of the stop block slidingly contacting the contact block, and a centrifuge disposed inside the body of the device.

[0006] Preferably, the outer surfaces of the stop block and the contact block are both arc-shaped, and the number of the contact block and the stop block are several groups distributed in a ring array. The upper end of the mounting sleeve is open, and a spring is sleeved on the outside of the piston rod. The spring is located between the piston cylinder and the contact block, and a positioning hole is opened through the upper outer surface of the fixing plate.

[0007] Preferably, the centrifuge has a placement slot on its upper side, a test tube is engaged and connected inside the placement slot, a suction tube is engaged and connected at the lower end of the piston cylinder, the lower end of the suction tube extends into the test tube, the piston cylinder is located inside the positioning hole, and a baffle is fixedly connected to the outer surface of the piston cylinder, the baffle is annular and engaged with the upper side of the fixed plate.

[0008] Preferably, a clamping assembly is provided on the lower side of the fixing plate. The clamping assembly includes a groove formed on the lower outer surface of the fixing plate. A slider is slidably connected inside the groove. An extrusion plate is fixedly connected to the lower outer surface of the slider. The outer surface of the extrusion plate engages and contacts the machine body.

[0009] Preferably, a traction bar is fixedly connected to the outer surface of the slider, and the end of the traction bar away from the slider is fixedly connected to the inner surface of the groove. The traction bar is made of elastic material. The number of the groove, the slider and the extrusion plate are all two sets and symmetrically distributed. The outer surface of the extrusion plate is arc-shaped.

[0010] Preferably, an adjustment component is provided inside the mounting sleeve. The adjustment component includes a screw threadedly connected to the lower end of the mounting sleeve, and a sliding plate is linearly slidably connected inside the mounting sleeve. The upper end of the screw is in rotatable contact with the sliding plate.

[0011] Preferably, a limiting rod is fixedly connected to the upper outer surface of the slide plate. The limiting rod is cylindrical. The upper outer surface of the slide plate is rotatably connected to the top rod. The limiting rod is engaged inside the top rod and rotatably connected to the top rod. The outer surface of the top rod is provided with scale lines.

[0012] Preferably, an extrusion assembly is provided inside the positioning hole. The extrusion assembly includes a guide groove formed inside the fixing plate. The guide groove is inclined and its lower end extends into the positioning hole. A guide rod is slidably connected inside the guide groove. A contact plate is fixedly connected to the lower end of the guide rod. The contact plate is arc-shaped and in close contact with the outer surface of the piston cylinder. An elastic band is fixedly connected between the contact plate and the side wall of the positioning hole. There are two sets of contact plates, which are symmetrically distributed on both sides of the piston cylinder. The contact plates are made of elastic material.

[0013] Preferably, a sealing assembly is provided on the lower side of the suction tube. The sealing assembly includes a limiting groove formed in the inner wall of the suction tube, and a limiting block is slidably connected to the inner surface of the limiting groove. There are two sets of limiting grooves and limiting blocks, which are symmetrically distributed. A movable sleeve is fixedly connected between the two sets of limiting blocks.

[0014] Preferably, a float plate is fixedly connected to the lower outer surface of the movable sleeve. The float plate is annular. A sphere is provided at the upper end of the movable sleeve. The lower side of the suction tube is conical. The sphere is made of elastic material. Both the float plate and the movable sleeve are made of lightweight material.

[0015] Compared with the prior art, the beneficial effects of the present invention are:

[0016] 1. This solution uses an extraction component where the contact block pulls the piston plate upward via the piston rod, drawing plasma from the test tube into the suction tube under gas pressure. This allows for the separation of plasma from the cell layer and enables simultaneous plasma separation and replacement of multiple blood samples. It effectively improves the speed of cold agglomeration processing of routine blood samples, significantly increasing sample processing efficiency while ensuring sample processing accuracy.

[0017] 2. This solution, by setting up a sealing component, seals the liquid outlet of the suction tube with a ball, which effectively reduces the risk of accidental dripping of plasma inside the suction tube under gravity during transport. This effectively reduces the risk of plasma contaminating the testing equipment, thereby further improving the safety and reliability of the blood routine cold agglutination treatment device during use.

[0018] 3. This solution, by setting up an adjustment component and adjusting the height of the movable plate via a screw, can adjust the amount of plasma extracted, thereby improving the accuracy of plasma extraction adjustment to a certain extent. This makes the operation of the blood routine cold agglomeration processing device more precise, and also further improves the functionality and application range of the blood routine cold agglomeration processing device. Attached Figure Description

[0019] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0021] Figure 2 This is a top view of the overall structure of the present invention;

[0022] Figure 3 For the present invention Figure 2 Sectional view along line AA;

[0023] Figure 4 For the present invention Figure 2 Sectional view along the BB direction;

[0024] Figure 5 For the present invention Figure 3 Enlarged view of point C in the middle;

[0025] Figure 6 For the present invention Figure 4 Enlarged view of point D;

[0026] Figure 7 For the present invention Figure 4 Enlarged view of point E in the middle;

[0027] Figure 8 For the present invention Figure 4 Enlarged diagram at point F;

[0028] Figure 9 For the present invention Figure 4 Enlarged diagram of point G in the middle.

[0029] Explanation of reference numerals in the attached figures:

[0030] 11. Body; 12. Extrusion plate; 13. Fixed plate; 14. Movable plate; 15. Positioning hole; 16. Centrifuge; 17. Baffle; 18. Mounting sleeve; 19. Top rod; 20. Scale line; 21. Screw; 22. Slide plate; 23. Limiting rod; 24. Piston cylinder; 25. Spring; 26. Contact block; 27. Stop block; 28. Piston rod; 29. ​​Guide rod; 30. Elastic band; 31. Contact plate; 32. Guide groove; 33. Slide groove; 34. Sliding block; 35. Traction bar; 36. Suction tube; 37. Placement groove; 38. Test tube; 39. Limiting groove; 40. Limiting block; 41. Movable sleeve; 42. Float plate; 43. Sphere; 44. Piston plate. Detailed Implementation

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] Please see Figures 1 to 9 This invention provides a technical solution:

[0033] A high-efficiency plasma exchange-type blood routine cold agglomeration processing device includes a body 11 and a fixed plate 13. An extraction component is provided on the outside of the fixed plate 13. The extraction component includes a piston cylinder 24 that engages with the outer surface of the fixed plate 13. A piston plate 44 is slidably connected to the inner surface of the piston cylinder 24. A piston rod 28 is fixedly connected to the upper outer surface of the piston plate 44. A contact block 26 is fixedly connected to the upper end of the piston rod 28. An installation sleeve 18 is fixedly connected to the middle of the outer surface of the fixed plate 13. A top rod 19 is rotatably connected to the inner surface of the installation sleeve 18. A movable plate 14 is fixedly connected to the upper outer surface of the top rod 19. A stop block 27 is fixedly connected to the lower outer surface of the movable plate 14. The lower outer surface of the stop block 27 slides in contact with the contact block 26. A centrifuge 16 is provided inside the body 11.

[0034] Both the outer surfaces of the stop block 27 and the contact block 26 are arc-shaped. The number of contact blocks 26 and the stop block 27 are several groups and distributed in a ring array. The upper end of the mounting sleeve 18 is open. A spring 25 is sleeved on the outside of the piston rod 28. The spring 25 is located between the piston cylinder 24 and the contact block 26. A positioning hole 15 is opened through the upper outer surface of the fixing plate 13.

[0035] The centrifuge 16 has a placement slot 37 on its upper side, and a test tube 38 is engaged and connected inside the placement slot 37. A suction tube 36 is engaged and connected at the lower end of the piston cylinder 24, and the lower end of the suction tube 36 extends into the test tube 38. The piston cylinder 24 is located inside the positioning hole 15. A baffle 17 is fixedly connected to the outer surface of the piston cylinder 24. The baffle 17 is annular and is engaged with the upper side of the fixing plate 13.

[0036] By employing the above technical solution, when processing blood routine samples exhibiting cold agglomeration using the plasma exchange method, a test tube 38 containing the blood sample is placed in a placement slot 37 on the surface of a centrifuge 16. The centrifuge body 11 is used to fix the centrifuge 16 in place. The blood sample is then centrifuged by the centrifuge 16 for a period of time, causing the cell layer and plasma in the blood to separate into layers. Plasma, due to its lowest density, will be on top of the test tube 38, while red blood cells, due to their highest density, will be at the bottom. The plasma is then removed from the test tube 38. During operation, an extraction assembly is installed to improve plasma extraction efficiency. The fixed plate 13 is placed on top of the centrifuge 16. The fixed plate 13, through the positioning hole 15, is used to place the piston cylinder 24. The baffle 17 on the surface of the piston cylinder 24, located above the fixed plate 13, acts as a blocking and positioning device for the piston cylinder 24. The fixed plate 13 provides rotatable support to the push rod 19 via the mounting sleeve 18, allowing the movable plate 14 to rotate around the push rod 19. When plasma needs to be extracted from the test tube 38, the operator rotates the movable plate 14. The movable plate 14 drives the stop block 27 to perform a circular motion. After moving a certain distance, the stop block 27 will contact the surface of the contact block 26. As the stop block 27 continues to move, it will press the contact block 26 downward. At this time, the contact block 26 will push the piston plate 44 downward through the piston rod 28. The downward movement of the piston plate 44 can expel some of the air inside the piston cylinder 24 and the suction tube 36. During the downward movement, the contact block 26 will compress the spring 25. As the movable plate 14 drives the stop block 27 to continue moving, when the stop block 27 contacts the surface of the contact block 26... After detachment, contact block 26 will move in the opposite direction and reset under the elastic force of spring 25. At this time, contact block 26 will pull piston plate 44 upward through piston rod 28. Under the action of gas pressure, plasma in test tube 38 will be drawn into suction tube 36, thereby separating plasma from cell layer. By setting extraction components, plasma separation and replacement processing can be performed on multiple groups of blood samples at the same time, which can effectively improve the cold agglomeration processing speed of blood routine samples. While ensuring sample processing accuracy, it can also significantly improve sample processing efficiency.

[0037] Specifically, such as Figure 4 and Figure 9 As shown, a clamping assembly is provided on the lower side of the fixed plate 13. The clamping assembly includes a groove 33 formed on the lower outer surface of the fixed plate 13. A slider 34 is slidably connected inside the groove 33. A pressing plate 12 is fixedly connected to the lower outer surface of the slider 34. The outer surface of the pressing plate 12 engages and contacts the machine body 11.

[0038] A traction bar 35 is fixedly connected to the outer surface of the slider 34. The end of the traction bar 35 away from the slider 34 is fixedly connected to the inner surface of the groove 33. The traction bar 35 is made of elastic material. There are two sets of grooves 33, sliders 34 and extrusion plates 12, which are symmetrically distributed. The outer surface of the extrusion plate 12 is arc-shaped.

[0039] By adopting the above technical solution, in order to ensure that the fixed plate 13 can be stably placed on the upper side of the centrifuge 16, a clamping assembly is provided. The slide groove 33 on the lower side of the fixed plate 13 is used to guide and support the slider 34, so that the squeezing plate 12 can slide linearly on the lower side of the fixed plate 13. During operation, the squeezing plate 12 is attached to the outer side of the machine body 11. The squeezing plate 12 stretches the traction bar 35 through the slider 34. At this time, the traction bar 35 applies a certain elastic force to the slider 34 and the squeezing plate 12, so that the squeezing plate 12 is tightly attached to the outer surface of the machine body 11. The fixed plate 13 is clamped and fixed by the two sets of squeezing plates 12, so that the fixed plate 13 is placed more stably. By setting the clamping assembly, not only can the stability of the fixed plate 13 be improved during the placement process, but also the squeezing plate 12 can be clamped on the surface of the machine body 11 with different diameters by adjusting the position of the squeezing plate 12, thereby effectively improving the application range of the blood routine cold agglutination processing device.

[0040] Specifically, such as Figure 3 , Figure 4 and Figure 6 As shown, an adjustment assembly is provided inside the mounting sleeve 18. The adjustment assembly includes a screw 21 that is threadedly connected to the lower end of the mounting sleeve 18, and a sliding plate 22 that is linearly slidably connected inside the mounting sleeve 18. The upper end of the screw 21 is in rotatable contact with the sliding plate 22.

[0041] A limiting rod 23 is fixedly connected to the upper outer surface of the slide plate 22. The limiting rod 23 is cylindrical. The upper outer surface of the slide plate 22 is rotatably connected to the top rod 19. The limiting rod 23 is engaged inside the top rod 19 and rotatably connected to the top rod 19. A scale line 20 is opened on the outer surface of the top rod 19.

[0042] By adopting the above technical solution, the blood routine cold agglomeration processing device is equipped with an adjustment component to adjust the amount of plasma extracted during use. When it is necessary to increase the amount of plasma extracted, the operator rotates the screw 21 clockwise. The screw 21, which is threadedly connected to the mounting sleeve 18, moves downward along its axis during rotation. At this time, the slide plate 22 moves downward under the gravity of the top rod 19 and the movable plate 14, thereby causing the top rod 19 and the movable plate 14 to move downward synchronously. After the movable plate 14 moves downward a certain distance, the distance between the stop block 27 and the contact block 26 will decrease. At this time, the distance that the stop block 27 drives the contact block 26 to move downward will increase accordingly, so that more air can be discharged from the suction tube 36 and the piston cylinder 24. When the piston plate 44 moves upward to reset, more plasma can be drawn. The scale line 20 on the surface of the push rod 19, together with the upper edge of the mounting sleeve 18, can observe the movement position of the push rod 19. By adjusting the height of the movable plate 14, the amount of plasma extracted can be adjusted, thereby improving the adjustment accuracy of the amount of plasma extracted to a certain extent, so as to make the operation of the blood routine cold agglutination processing device more precise.

[0043] Specifically, such as Figure 4 and Figure 7 As shown, a pressing assembly is provided inside the positioning hole 15. The pressing assembly includes a guide groove 32 opened inside the fixing plate 13. The guide groove 32 is inclined and its lower end extends into the positioning hole 15. A guide rod 29 is slidably connected inside the guide groove 32. A contact plate 31 is fixedly connected to the lower end of the guide rod 29. The contact plate 31 is arc-shaped and in contact with the outer surface of the piston cylinder 24. An elastic band 30 is fixedly connected between the contact plate 31 and the side wall of the positioning hole 15. There are two sets of contact plates 31, which are symmetrically distributed on both sides of the piston cylinder 24. The contact plates 31 are made of elastic material.

[0044] By adopting the above technical solution, in order to further improve the operational accuracy in the plasma extraction process, a squeezing assembly is set up. When the piston cylinder 24 and the baffle 17 are placed on the upper side of the fixed plate 13, the lower end of the baffle 17 will contact the upper end of the guide rod 29. Under the action of the piston cylinder 24 and its own gravity, the baffle 17 presses the guide rod 29, causing the guide rod 29 to slide downward inside the guide groove 32. During the movement, the guide rod 29 will drive the contact plate 31 to move downward synchronously, so that the two sets of contact plates 31 are attached to the surface of the piston cylinder 24 to clamp and fix the piston cylinder 24, thereby effectively improving the stability of the piston cylinder 24 in the plasma extraction process, and further improving the operational accuracy of the blood routine cold agglutination processing device. During the movement, the contact plate 31 will pull the elastic band 30. When the piston cylinder 24 is removed, the contact plate 31 will move in the opposite direction under the elastic force of the elastic band 30, thereby causing the contact plate 31 to disengage from the piston cylinder 24.

[0045] Specifically, such as Figure 4 and Figure 8 As shown, a sealing assembly is provided on the lower side of the suction tube 36. The sealing assembly includes a limiting groove 39 formed on the inner wall of the suction tube 36. A limiting block 40 is slidably connected to the inner surface of the limiting groove 39. There are two sets of limiting grooves 39 and limiting blocks 40, which are symmetrically distributed. A movable sleeve 41 is fixedly connected between the two sets of limiting blocks 40.

[0046] A float plate 42 is fixedly connected to the lower outer surface of the movable sleeve 41. The float plate 42 is in the shape of a ring. A ball 43 is provided at the upper end of the movable sleeve 41. The lower side of the suction tube 36 is in the shape of a cone. The ball 43 is made of elastic material. Both the float plate 42 and the movable sleeve 41 are made of lightweight material.

[0047] By adopting the above technical solution, after the plasma is drawn into the suction tube 36, the piston cylinder 24 and the suction tube 36 need to be transferred. To reduce the probability of accidental dripping of plasma due to gravity during the transfer process, a sealing component is provided. When the suction tube 36 draws plasma, the lower end of the suction tube 36 is placed inside the test tube 38. At this time, the float 42, under the buoyancy of the blood, will drive the movable sleeve 41 to move into the suction tube 36. The limiting groove 39 opened inside the suction tube 36 is used to slide and support the limiting block 40. The limiting block 40 can guide and limit the movable sleeve 41, so that the movable sleeve 41 moves linearly upward inside the suction tube 36. During the movement, the movable sleeve 41 will push the ball 43, causing the ball 43 to move upward synchronously. At this time, the plasma will flow from the suction tube 36. The blood is drawn into the gap between the suction tube 36 and the ball 43. After the plasma extraction is completed, as the suction tube 36 is gradually removed from the test tube 38, the float 42 will detach from the blood. The blood remaining on the surface of the float 42 is absorbed by the cotton ball. At this time, the float 42 and the movable sleeve 41 move downward under their own gravity. The ball 43 moves downward synchronously and locks into the lower end of the suction tube 36. This seals the outlet end of the suction tube 36 with the ball 43. When the suction tube 36 is transported, the risk of accidental dripping of the plasma inside the suction tube 36 under gravity is effectively reduced, thereby reducing the risk of plasma contaminating the testing equipment. This further improves the safety and reliability of the blood routine cold agglutination treatment device.

[0048] Working principle: When using the blood routine cold agglutination processing device, the test tube 38 containing the blood sample is placed in the placement slot 37 on the surface of the centrifuge 16. Then, the blood sample is centrifuged by the centrifuge 16, causing the cell layer and plasma in the blood to separate. The stop block 27 will press the contact block 26 downward. At this time, the contact block 26 will push the piston plate 44 downward through the piston rod 28. The downward movement of the piston plate 44 can expel some of the air inside the piston cylinder 24 and the suction tube 36. The contact block 26 will move back to its original position under the elastic force of the spring 25. Under the action of gas pressure, the plasma in the test tube 38 is drawn into the suction tube 36, thereby separating the plasma from the cell layer. The fixing plate 13 is clamped and fixed by two sets of squeezing plates 12, thereby fixing the fixing plate 13. 3. The placement is more stable. During the movement of the guide rod 29, the contact plate 31 will move down synchronously, so that the two sets of contact plates 31 will fit against the surface of the piston cylinder 24 to clamp and fix the piston cylinder 24, thereby effectively improving the stability of the piston cylinder 24 during the plasma extraction process. The ball 43 is engaged with the lower end of the suction tube 36, which can seal the liquid outlet of the suction tube 36. When the suction tube 36 is transported, it can effectively reduce the risk of accidental dripping of the plasma inside the suction tube 36 under the action of gravity. By adjusting the height of the movable plate 14, the amount of plasma extracted can be adjusted, thereby improving the adjustment accuracy of the plasma extraction amount to a certain extent.

[0049] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A high-efficiency plasma exchange-type blood routine cold agglomeration treatment device, comprising a body (11) and a fixing plate (13), characterized in that: An extraction assembly is provided on the outside of the fixed plate (13). The extraction assembly includes a piston cylinder (24) that engages with the outer surface of the fixed plate (13). A piston plate (44) is slidably connected to the inner surface of the piston cylinder (24). A piston rod (28) is fixedly connected to the upper outer surface of the piston plate (44). A contact block (26) is fixedly connected to the upper end of the piston rod (28). An installation sleeve (18) is fixedly connected to the middle of the outer surface of the fixed plate (13). A top rod (19) is rotatably connected to the inner surface of the installation sleeve (18). A movable plate (14) is fixedly connected to the upper outer surface of the top rod (19). A stop block (27) is fixedly connected to the lower outer surface of the movable plate (14). The lower outer surface of the stop block (27) slides in contact with the contact block (26). A centrifuge (16) is provided inside the machine body (11).

2. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 1, characterized in that: The outer surfaces of the stop block (27) and the contact block (26) are both arc-shaped. The number of the contact block (26) and the stop block (27) are several groups and arranged in a ring array. The upper end of the mounting sleeve (18) is open. A spring (25) is sleeved on the outside of the piston rod (28). The spring (25) is located between the piston cylinder (24) and the contact block (26). A positioning hole (15) is opened through the upper outer surface of the fixing plate (13).

3. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 2, characterized in that: The centrifuge (16) has a placement groove (37) on its upper side, and a test tube (38) is engaged and connected inside the placement groove (37). A suction tube (36) is engaged and connected at the lower end of the piston cylinder (24), and the lower end of the suction tube (36) extends into the test tube (38). The piston cylinder (24) is located inside the positioning hole (15), and a baffle (17) is fixedly connected to the outer surface of the piston cylinder (24). The baffle (17) is annular and engaged with the upper side of the fixing plate (13).

4. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 3, characterized in that: A clamping assembly is provided on the lower side of the fixed plate (13). The clamping assembly includes a groove (33) formed on the lower outer surface of the fixed plate (13). A slider (34) is slidably connected inside the groove (33). A pressing plate (12) is fixedly connected to the lower outer surface of the slider (34). The outer surface of the pressing plate (12) is engaged and in contact with the machine body (11).

5. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 4, characterized in that: The outer surface of the slider (34) is fixedly connected to a traction bar (35). The end of the traction bar (35) away from the slider (34) is fixedly connected to the inner surface of the groove (33). The traction bar (35) is made of elastic material. The number of the groove (33), slider (34) and extrusion plate (12) are two sets and symmetrically distributed. The outer surface of the extrusion plate (12) is arc-shaped.

6. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 5, characterized in that: An adjustment component is provided inside the mounting sleeve (18). The adjustment component includes a screw (21) threadedly connected to the lower end of the mounting sleeve (18). A sliding plate (22) is linearly slidably connected inside the mounting sleeve (18). The upper end of the screw (21) is in rotatable contact with the sliding plate (22).

7. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 6, characterized in that: A limiting rod (23) is fixedly connected to the upper outer surface of the slide plate (22). The limiting rod (23) is cylindrical. The upper outer surface of the slide plate (22) is rotatably connected to the top rod (19). The limiting rod (23) is engaged inside the top rod (19) and rotatably connected to the top rod (19). The outer surface of the top rod (19) is provided with scale lines (20).

8. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 7, characterized in that: An extrusion assembly is provided inside the positioning hole (15). The extrusion assembly includes a guide groove (32) opened inside the fixing plate (13). The guide groove (32) is inclined and its lower end extends into the positioning hole (15). A guide rod (29) is slidably connected inside the guide groove (32). A contact plate (31) is fixedly connected to the lower end of the guide rod (29). The contact plate (31) is arc-shaped and in contact with the outer surface of the piston cylinder (24). An elastic band (30) is fixedly connected between the contact plate (31) and the side wall of the positioning hole (15). There are two sets of contact plates (31) symmetrically distributed on both sides of the piston cylinder (24). The contact plates (31) are made of elastic material.

9. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 8, characterized in that: A sealing assembly is provided on the lower side of the suction tube (36). The sealing assembly includes a limiting groove (39) formed on the inner wall of the suction tube (36). A limiting block (40) is slidably connected to the inner surface of the limiting groove (39). There are two sets of limiting grooves (39) and limiting blocks (40) and they are symmetrically distributed. A movable sleeve (41) is fixedly connected between the two sets of limiting blocks (40).

10. The high-efficiency plasma exchange type blood routine cold agglomeration treatment device according to claim 9, characterized in that: A float plate (42) is fixedly connected to the lower outer surface of the movable sleeve (41). The float plate (42) is in the shape of a ring. A ball (43) is provided at the upper end of the movable sleeve (41). The lower side of the suction tube (36) is conical. The ball (43) is made of elastic material. Both the float plate (42) and the movable sleeve (41) are made of lightweight material.

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