Traditional Chinese medicine composition for relieving swelling and pain and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for relieving swelling and pain and a preparation method thereof, and relates to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine components: golden cypress, dandelion, gallnut, patrinia, fructus forsythiae, safflower, corydalis tuber, pseudo-ginseng, ginkgo leaf, rice vinegar, borneol and honey. Amur corktree bark and Chinese gall have a good curative effect on acute and chronic soft tissue injuries, can relieve and eliminate local aseptic inflammation, can improve local microcirculation, can promote repair of injured tissues, and can promote skin ecchymosis and hematoma fading, the traditional Chinese medicine is an externally-applied good medicine for treating acute soft tissue injuries, the medication object is not limited, and the traditional Chinese medicine can be used for children and adults and has a good application prospect. The traditional Chinese medicine composition has the advantages that the curative effect of the traditional Chinese medicine composition meets the clinical requirements, at present, various drugs for treating contusion, tenosynovitis, bone fracture and invasive inflammation clinically exist, but most drugs take effect slowly and are poor in applicability after being used, and the traditional Chinese medicine composition preparation is remarkable in effect and convenient to use in clinical use.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to a traditional Chinese medicine composition for reducing swelling and relieving pain, and its preparation method. Background Technology

[0002] Soft tissue injuries and orthopedic diseases are a group of diseases caused by various acute traumas or chronic strains, resulting in damage to the superficial and deep fascia, muscles, tendons, tendon sheaths, and bones. Their onset is usually closely related to lifestyle habits, age, occupation, and degenerative changes. Clinical symptoms include pain, swelling, deformity, and limited mobility; in severe cases, muscle atrophy and functional impairment may occur. Mild injuries usually have a good prognosis, and symptoms can be effectively relieved through medication, immobilization, and cold compresses. However, severe injuries have a poorer prognosis and may require surgical treatment or even longer periods of treatment and rehabilitation. Western medicine believes that the causes of soft tissue injuries and orthopedic diseases mainly include external forces (such as falls and impacts), chronic strain, sports injuries, and internal factors (such as osteoporosis and insufficient muscle strength). These factors lead to impaired local blood circulation in soft tissues, causing the release of inflammatory mediators and triggering inflammatory responses. In terms of treatment, in the early stages of injury, adequate rest is essential. If necessary, immobilization devices such as plaster casts and bandages can be used to reduce pain and promote healing. Over-the-counter analgesics (such as nonsteroidal anti-inflammatory drugs) and anti-inflammatory drugs can be taken to relieve pain and inflammation. Physical therapy can be used to promote inflammation resolution and tissue repair. Severe injuries may require surgery to restore function. For reducing swelling and pain, dehydrating agents, hormones, or nonsteroidal anti-inflammatory drugs are mainly used. However, because these drugs can damage the gastric mucosa, patients have significant concerns about their use. In Traditional Chinese Medicine (TCM), this type of disease falls under the category of "Bi syndrome." The *Zhu Bing Yuan Hou Lun* (Treatise on the Causes and Symptoms of Various Diseases) states, "Bi syndrome is caused by the combined invasion of wind, cold, and dampness." The occurrence of Bi syndrome is primarily due to insufficient vital energy (Qi) leading to the invasion of pathogenic factors such as wind, cold, dampness, and heat. These external pathogens invade the body, obstructing the meridians and hindering the flow of Qi and blood, resulting in symptoms such as swelling, pain, numbness, and difficulty in flexion and extension of muscles, tendons, bones, and joints. Currently, TCM treats Bi syndrome through syndrome differentiation and treatment, employing methods such as medication, external application, and acupuncture. This approach offers multiple options, a systematic approach, and holistic regulation, achieving a comprehensive therapeutic effect that addresses both the symptoms and the root cause. However, currently, there are very few external application Chinese herbal medicines used clinically to reduce swelling, which cannot meet the diverse needs of different patients. Based on the current clinical treatment status of soft tissue injuries and orthopedic diseases, there is an urgent need to provide a topical Chinese medicine composition that can reduce swelling and relieve pain, with few side effects and high acceptance. Summary of the Invention

[0003] To address the shortcomings of existing technologies, this invention provides a traditional Chinese medicine composition for reducing swelling and relieving pain, and its preparation method, thus solving the problems mentioned in the background art.

[0004] To achieve the above objectives, the present invention is implemented through the following technical solution: a traditional Chinese medicine composition for reducing swelling and relieving pain and its preparation method, wherein the traditional Chinese medicine composition is made from the following traditional Chinese medicine components: Phellodendron bark, dandelion, gallnut, Patrinia scabiosaefolia, Forsythia suspensa, safflower, Corydalis yanhusuo, Panax notoginseng, Ginkgo biloba leaf, rice vinegar, borneol and honey.

[0005] Furthermore, the raw material composition and weight fraction of the prepared traditional Chinese medicine composition are as follows: 15-20 parts of Phellodendron bark, 5-10 parts of dandelion, 25-40 parts of gallnut, 1-5 parts of Patrinia scabiosaefolia, 4-10 parts of Forsythia suspensa, 5-10 parts of safflower, 1-8 parts of Corydalis yanhusuo; 6-8 parts of Panax notoginseng; 1-5 parts of Ginkgo biloba leaf, 1-10 parts of rice vinegar, 3-5 parts of borneol, and 5-10 parts of honey.

[0006] Furthermore, the raw material composition and weight fraction of the prepared traditional Chinese medicine composition are as follows: 15 parts of Phellodendron bark, 5 parts of dandelion, 30 parts of gallnut, 2 parts of Patrinia scabiosaefolia, 5 parts of Forsythia suspensa, 5 parts of safflower, 8 parts of Corydalis yanhusuo; 8 parts of Panax notoginseng; 2 parts of Ginkgo biloba leaf, 10 parts of rice vinegar, 5 parts of borneol, and 5 parts of honey.

[0007] Furthermore, the raw material composition and weight fraction of the prepared traditional Chinese medicine composition are as follows: 20 parts of Phellodendron bark, 10 parts of dandelion, 40 parts of gallnut, 1 part of Patrinia scabiosaefolia, 4 parts of Forsythia suspensa, 5 parts of safflower, 1 part of Corydalis yanhusuo; 6 parts of Panax notoginseng; 1 part of Ginkgo biloba leaf, 4 parts of rice vinegar, 3 parts of borneol, and 5 parts of honey.

[0008] Furthermore, the preparation of the traditional Chinese medicine composition is a topical ointment.

[0009] A method for preparing a traditional Chinese medicine composition for reducing swelling and relieving pain includes the following steps: S1. Take each of the medicinal materials of any of the weight components in the Chinese herbal composition, mix them and then pulverize them with a pulverizer. The fineness of the powder is 50 mesh. The powder after coarse powdering is pulverized by ultra-micro pulverization technology so that the average particle size of the powder is less than 50 μm. S2. Put the pulverized medicine powder into the heating tank, add 2000-3000mL of water and rice vinegar, and heat at 180℃ for 1 hour while stirring. Extract 200-250mL of the supernatant liquid for later use. S3, 100 mesh filtration, then ultrafiltration through an ultrafiltration column with a molecular weight cutoff of 10000, the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.20-1.25 at 80℃, and then set aside for later use; S4. Add water to the filter residue, heat it a second time, boil for 45-60 minutes, filter, and reserve the filtrate. S5. After mixing the extract and supernatant, add 2-4 times the amount of distilled water and stir well. Heat to boiling for 30 minutes, let stand for 2 hours, extract and filter to obtain filtrate. Fill and seal the filtrate, autoclave at 122℃-125℃ for 20-30 minutes, add borneol, mix well, cool, and the ointment is obtained. Dispense into containers.

[0010] The efficacy and pharmacological effects of the medicinal materials selected in this invention are as follows: Traditional Chinese medicine believes that applying medicated plasters directly to the injured area can promote the opening of pores, smooth flow of qi and blood, improve local blood circulation, and facilitate the repair of damaged tissues, thus resulting in good therapeutic effects. Xu Huixi, a famous physician of the Qing Dynasty, stated: "Applying medicated plasters blocks the flow of qi, allowing the medicinal properties to enter the pores through the skin, clearing the meridians and collaterals, or drawing out the pathogens, thus stimulating and attacking them. This is more effective than oral medication; this is a truly wonderful method." Phellodendron bark and gallnut have good therapeutic effects on acute and chronic soft tissue injuries. They can reduce and eliminate local aseptic inflammation, improve local microcirculation, promote the repair of damaged tissues, and promote the resolution of skin ecchymosis and hematoma. They are excellent external medicines for treating acute soft tissue injuries. Phellodendron bark: Properties: Bitter, cold; enters the kidney, bladder, and large intestine meridians. It has the functions of clearing heat and detoxifying, drying dampness and reducing swelling. *Compendium of Materia Medica* states it is used for boils and blistering caused by insects, dysentery, hematochezia, and killing termites. *Essentials of Drug Use* states it treats unbearable pain from sores. Rice vinegar, originally called bitter wine, is also known as sour vinegar. It has medicinal uses; its taste is sour and bitter, and its nature is warm. It has the effects of dispersing blood stasis and reducing swelling and toxicity. Phellodendron bark has the effects of clearing heat and drying dampness, detoxifying and healing sores, removing blood stasis and dissipating nodules, and stopping bleeding. Its main component is berberine hydrochloride, and it also contains berberine, magnoflorine, and other components. It has antibacterial, hypotensive, and sedative effects, and can reduce capillary permeability. Gallnut, also known as clam shell, hundred-insect granary, and wood aconite, possesses various clinical effects, including astringing the lungs and reducing heat, astringing the intestines and stopping diarrhea, consolidating essence and reducing urination, stopping sweating, stopping bleeding, detoxifying, and astringing sores. The pharmacological activity of gallnut is relatively complex. Tannins and gallic acid in gallnut have a precipitating effect on proteins. Upon contact with skin, mucous membranes, or ulcers, tissue proteins are coagulated, forming a membrane that exhibits an astringent effect. Simultaneously, small blood vessels are compressed and constricted, causing blood clotting and hemostasis. The astringent effect coagulates proteins in glandular cells, inhibiting secretion and drying mucous membranes. The precipitation of proteins at nerve endings can produce a weak local anesthetic effect. The combined effect of these two herbs is significant. Animal experiments have demonstrated good anti-inflammatory, analgesic, microcirculation-improving, and swelling-reducing effects, without irritating intact skin. Borneol: Slightly cold in nature, bitter and pungent in taste, and enters the heart, spleen, and lung meridians. It has the effects of dispersing stagnant heat and toxins, dispersing pungent and aromatic properties, clearing the meridians and penetrating the interior, dispelling wind and opening the orifices, killing parasites, relieving pain and itching, and removing ulcers and putrefaction. Modern pharmacological studies have shown that borneol can inhibit the growth of Escherichia coli and Staphylococcus aureus, and has anti-inflammatory, antiviral, and analgesic effects. In addition, borneol promotes transdermal absorption, increasing the amount of drug absorbed by the skin and mucous membranes. Ginkgo biloba leaves: Functions and indications: relieves asthma, promotes blood circulation and removes blood stasis, relieves pain; used for cough and asthma due to lung deficiency, coronary heart disease, angina pectoris, and hyperlipidemia; Dandelion: The dried whole herb of Taraxacum officinale, Taraxacum mongolicum, or several species of the same genus in the Asteraceae family. It has the functions of clearing heat and detoxifying, reducing swelling and dissipating nodules, promoting diuresis and relieving strangury. It is used for boils and carbuncles, mastitis, scrofula, red eyes, sore throat, lung abscess, intestinal abscess, damp-heat jaundice, and painful urination due to heat. Patrinia scabiosifolia: It can effectively clear heat toxins from the body and has a relieving effect on various diseases caused by heat toxins, such as colds, coughs, oral ulcers, sore throats, boils and carbuncles, pneumonia, tonsillitis, etc. Its active ingredients can effectively inhibit the growth of bacteria and viruses and help the body clear the source of infection. Forsythia: Its medicinal properties are bitter and cold, primarily entering the heart meridian. It can penetrate the exterior to relieve muscle tension, clear heat and expel wind, possessing the effects of clearing heat and detoxifying. It can effectively relieve symptoms such as fever, cough, headache, and sore throat caused by wind-heat colds. Clinically, forsythia is also commonly used to treat febrile diseases, such as the initial stage of febrile diseases and irritability. In addition, forsythia can also treat inflammatory skin diseases such as carbuncles, boils, and erysipelas, as well as internal medicine diseases such as acute nephritis and allergic purpura. Safflower: It is pungent and warm, enters the heart and liver blood, can promote blood circulation and relieve pain. Safflower has the effect of removing blood stasis, which can reduce blood stasis to a certain extent. It has a good therapeutic effect on various blood stasis pains, such as headache, chest pain, angina pectoris, joint pain, and pain caused by falls and injuries. Corydalis: Widely used to treat various types of pain, such as headaches, toothaches, arthritis pain, chest and rib pain, and abdominal pain. Its alkaloids and other chemical components promote blood circulation, eliminate blood stasis, and regulate the flow of Qi, thus effectively relieving pain. Certain components in Corydalis can inhibit the excitability of the central nervous system, putting the brain in a relatively calm and relaxed state, thereby exerting a sedative and hypnotic effect and helping to improve symptoms such as insomnia and anxiety. Corydalis also has antibacterial and anti-inflammatory effects and can be used to treat symptoms such as fever, pharyngitis, and oral ulcers caused by infection. Panax notoginseng contains notoginsenosides and notoginseng monomers, which have various biological activities. They can promote platelet aggregation, enhance the stability of blood vessel walls, and reduce blood leakage and bleeding, thereby playing a hemostatic role. At the same time, Panax notoginseng can also relieve various pains, especially bruises and swelling caused by falls and injuries. Honey can be used to treat symptoms of spleen and stomach disharmony such as abdominal pain, regulate qi and blood, and balance yin and yang. It also has a certain improving effect on symptoms such as physical weakness and post-illness recovery. Simultaneously, it can moisturize the skin, improve skin texture, and relieve symptoms such as dry and itchy skin. Honey has analgesic properties and can be used to treat various pain symptoms, such as abdominal pain and dysmenorrhea. Furthermore, it can soothe nerves and relieve muscle pain, and has a certain improving effect on symptoms such as neuropathic pain and muscle pain. Honey can also be used to treat surgical diseases such as slow-healing sores and burns. Additionally, it can clear toxins from the body, promote the excretion of metabolic waste, and has a certain effect on detoxification, beauty enhancement, and improving constipation.

[0011] This invention provides a traditional Chinese medicine composition for reducing swelling and relieving pain, and its preparation method, which has the following advantages compared with the prior art: The herbal composition of this invention has a reasonable formula and has significant therapeutic effects on contusions, tenosynovitis, bone injuries, and infiltrative inflammation. It can relieve patients' discomfort in a short time and has remarkable therapeutic effects.

[0012] The composition of this invention is prepared entirely from traditional Chinese medicine. The formula is simple, and the ingredients are commonly used in traditional Chinese medicine. It has few toxic side effects, high safety, and strong practicality.

[0013] The target population for this invention is not limited; it can be used for both children and adults, and its efficacy meets clinical needs. Currently, there are many types of drugs used clinically to treat contusions, tenosynovitis, bone injuries, and infiltrative inflammation, but most of them are slow to take effect and have poor applicability. The traditional Chinese medicine composition preparation of this invention has significant effects in clinical use, is convenient to use, has a wide range of applications, and no adverse reactions have been found, thus providing patients with further clinical options. Detailed Implementation

[0014] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0015] A traditional Chinese medicine composition for reducing swelling and relieving pain, the composition being made from the following traditional Chinese medicine components: Phellodendron bark, dandelion, gallnut, Patrinia scabiosaefolia, Forsythia suspensa, safflower, Corydalis yanhusuo, Panax notoginseng, Ginkgo biloba leaf, rice vinegar, borneol, and honey.

[0016] The raw materials and their weight fractions for making the traditional Chinese medicine composition are as follows: 15-20 parts of Phellodendron bark, 5-10 parts of dandelion, 25-40 parts of gallnut, 1-5 parts of Patrinia scabiosaefolia, 4-10 parts of Forsythia suspensa, 5-10 parts of safflower, 1-8 parts of Corydalis yanhusuo, 6-8 parts of Panax notoginseng, 1-5 parts of Ginkgo biloba leaf, 1-10 parts of rice vinegar, 3-5 parts of borneol, and 5-10 parts of honey. Example

[0017] The raw materials and their weight fractions for making the traditional Chinese medicine composition are as follows: 15 parts of Phellodendron bark, 5 parts of dandelion, 30 parts of gallnut, 2 parts of Patrinia scabiosaefolia, 5 parts of Forsythia suspensa, 5 parts of safflower, 8 parts of Corydalis yanhusuo, 8 parts of Panax notoginseng, 2 parts of Ginkgo biloba leaf, 10 parts of rice vinegar, 5 parts of borneol, and 5 parts of honey. Example

[0018] The raw materials and their weight fractions for making the Chinese herbal composition are as follows: 20 parts of Phellodendron bark, 10 parts of dandelion, 40 parts of gallnut, 1 part of Patrinia scabiosaefolia, 4 parts of Forsythia suspensa, 5 parts of safflower, 1 part of Corydalis yanhusuo; 6 parts of Panax notoginseng; 1 part of Ginkgo biloba leaf, 4 parts of rice vinegar, 3 parts of borneol, and 5 parts of honey.

[0019] The traditional Chinese medicine composition is prepared as a topical ointment.

[0020] A method for preparing a traditional Chinese medicine composition for reducing swelling and relieving pain includes the following steps: S1. Take each of the medicinal materials of any of the weight components in the Chinese herbal composition, mix them and then pulverize them with a pulverizer. The fineness of the powder is 50 mesh. The powder after coarse powdering is pulverized by ultra-micro pulverization technology so that the average particle size of the powder is less than 50 μm. S2. Put the pulverized medicine powder into the heating tank, add 2000-3000mL of water and rice vinegar, and heat at 180℃ for 1 hour while stirring. Extract 200-250mL of the supernatant liquid for later use. S3, 100 mesh filtration, then ultrafiltration through an ultrafiltration column with a molecular weight cutoff of 10000, the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.20-1.25 at 80℃, and then set aside for later use; S4. Add water to the filter residue, heat it a second time, boil for 45-60 minutes, filter, and reserve the filtrate. S5. After mixing the extract and supernatant, add 2-4 times the amount of distilled water and stir well. Heat to boiling for 30 minutes, let stand for 2 hours, extract and filter to obtain filtrate. Fill and seal the filtrate, autoclave at 122℃-125℃ for 20-30 minutes, add borneol, mix well, cool, and the ointment is obtained. Dispense into containers.

[0021] Identification: (1) Take this product and observe it under a microscope: the stone cells are bright yellow, round or spindle-shaped, with a diameter of 35~128μm. Some are branched with sharp tips, thick walls, and obvious stratification.

[0022] (2) Take 5g of this product, add 5ml of methanol, sonicate for 15 minutes, filter, and use the filtrate as the test solution. Separately, take gallic acid reference standard, add methanol to prepare a solution containing 1mg per ml, and use this as the reference solution. Perform thin-layer chromatography (Chinese Pharmacopoeia 2020 Edition, Part IV, General Chapter 0502), apply 2μl of each of the above two solutions to the same silica gel GF254 thin-layer plate, use chloroform-ethyl formate-formic acid (5:5:1) as the developing solvent, develop, remove, air dry, and examine under ultraviolet light (254nm). In the chromatogram of the test sample, spots of the same color appear at the corresponding positions as in the chromatogram of the reference standard. Typical case description: Ms. Chen, 61 years old, presented to the hospital on May 4, 2016, with the chief complaint of "swelling and pain in both knees for one month," and was diagnosed with "bilateral knee osteoarthritis." Symptoms included: pain and swelling in both knees, sharp, stabbing pain, tenderness upon pressure, worsening with walking, limited mobility, and exacerbated pain when going up and down stairs; significant pain in both knees; fever accompanied by general body aches; normal appetite and bowel movements; normal sleep; dark tongue with a thin white coating; and a wiry pulse. Swelling in both knees was present, with tenderness upon palpation and percussion at the Neixi and Nasal points, patellar tenderness, limited mobility, and positive drawer and grinding tests. Patellar tap test (+), McMurray's sign (+), bilateral knee anteroposterior and lateral radiographs showed degenerative changes in both knee joints. Bone marrow ultrasound of both knee joints showed joint effusion and synovial thickening in the left knee. Symptomatic treatment including dehydration, anti-inflammation, nerve nutrition, and circulation improvement was administered, along with topical ointment to reduce swelling and pain. After treatment, tenderness at Neixi and Dubi points was negative, percussion pain was negative, patellar tenderness was negative, movement was limited, drawer test was negative, grinding test was negative, patellar tap test was negative, McMurray's sign was negative, and swelling and pain in both knee joints significantly improved. The patient experienced no adverse reactions such as local redness, swelling, itching, or papules during treatment. Mr. Zhang, male, 62 years old, came to our hospital on March 24, 2016, with the chief complaint of "swelling and pain in both knees for 1 year, worsening in the past 3 days," and was diagnosed with "bilateral knee osteoarthritis." Symptoms included: pain and swelling in both knees, sharp, stabbing pain, tenderness upon pressure, worsening with walking, limited mobility, and exacerbated pain when going up and down stairs. He had a normal appetite, normal bowel movements, and poor sleep. His tongue was dark with a thin white coating, and his pulse was wiry. Bilateral knee swelling was present, with tenderness at Neixi and Dubi points, percussion tenderness, patellar tenderness, limited mobility, and positive drawer test, grinding test, patellar tap test, and McMurray's sign. Anteroposterior and lateral radiographs of both knees showed degenerative changes. Color Doppler ultrasound of both knees showed joint effusion and synovial thickening in the right knee. Treatment included dehydration, anti-inflammation, nerve nutrition, and circulation improvement, combined with external application of clam shell ointment to reduce swelling and pain. After treatment, tenderness at Neixi and Dubi points was negative, percussion pain was negative, patellar tenderness was negative, movement was limited, drawer test was negative, grinding test was negative, patellar tapping test was negative, McMurray's sign was positive, and swelling and pain in both knee joints improved. The patient experienced no adverse reactions such as local redness, swelling, itching, or papules during treatment.

[0023] Ms. Ge, 84 years old, presented to our hospital on December 24, 2015, with the chief complaint of "lower back pain and limited mobility for 1 hour after a car accident." She was diagnosed with "compression fracture of the L1-L3 lumbar vertebrae." Symptoms included: lower back pain, limited mobility, and occasional dizziness. She had no fever, poor appetite and sleep, but normal bowel movements. Her tongue was dark with a white coating, and her pulse was deep and hesitant. The patient presented with lower back pain, limited range of motion, and tenderness upon palpation of the lower back, particularly at the L1, L2, and L3 vertebrae. Percussion was also positive, but no crepitus or abnormal movement was palpable. Straight leg raise test: L30° (+), R30° (+); reinforced test: L (+), R (+); ASR: L (+), R (+); PSR: L (+), R (+). Lumbar disc CT scan revealed lumbar degenerative changes, wedge-shaped deformities at L1, L2, and L3 vertebrae, and disc bulging at L3 / 4, L4 / 5, and L5 / S1. Symptomatic treatment including promoting blood circulation, relieving pain, and promoting bone healing was administered, along with external application of clam shell ointment to reduce swelling and pain. After treatment, the lower back pain significantly decreased. Tenderness upon palpation of the lower back, tenderness upon percussion of the T11 spinous process (±), and no crepitus or abnormal movement were palpable. Tenderness upon palpation and percussion of the left transverse processes of the L1-L3 vertebrae remained (±). No adverse reactions such as local redness, swelling, itching, or papules occurred during the treatment.

[0024] Ms. Wei, 30 years old, presented with swelling and pain in her right knee joint two months prior without any obvious cause, accompanied by limited mobility. Despite comprehensive treatment, her symptoms persisted without relief and worsened one week prior. She presented to our hospital on February 20, 2016, with the chief complaint of "swelling and pain in the right knee joint with limited mobility for two months, worsening in the past week." She was diagnosed with "right knee osteoarthritis." Symptoms included: swelling, pain, limited mobility, and difficulty walking in the right knee joint. She had no fever, night sweats, weight loss, or fatigue. Her appetite and bowel movements were normal, and she slept well. Her tongue was dark with a white coating, and her pulse was deep and hesitant. The patient presented with swelling and tenderness in the right knee joint, limited range of motion (R: 0°~90°), palpable friction during flexion and extension, negative lateral stress test (L: (-), negative R), negative grinding test (L: (-), positive R), negative drawer test (L: (-), negative R), quadriceps strength (L: Grade V, R: Grade V), negative patellar taper test (L: (-), positive R). Anteroposterior and lateral radiographs of the right knee joint showed a pointed intercondylar eminence and narrowing of the medial joint space. Symptomatic treatment including promoting blood circulation, reducing swelling and pain was administered, along with topical application of clam shell ointment for swelling and pain relief. After treatment, the knee symptoms disappeared, right knee joint movement was unrestricted, and tenderness was absent. The patient experienced no adverse reactions such as local redness, swelling, itching, or swelling during treatment.

[0025] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

Claims

1. A traditional Chinese medicine composition for reducing swelling and relieving pain, characterized in that: The traditional Chinese medicine composition is made from the following traditional Chinese medicine components: Phellodendron bark, dandelion, gallnut, Patrinia scabiosaefolia, forsythia, safflower, Corydalis yanhusuo, Panax notoginseng, ginkgo leaf, rice vinegar, borneol, and honey.

2. The traditional Chinese medicine composition for reducing swelling and relieving pain according to claim 1, characterized in that: The raw materials and their weight fractions for making the traditional Chinese medicine composition are as follows: 15-20 parts of Phellodendron bark, 5-10 parts of dandelion, 25-40 parts of gallnut, 1-5 parts of Patrinia scabiosaefolia, 4-10 parts of Forsythia suspensa, 5-10 parts of safflower, 1-8 parts of Corydalis yanhusuo, 6-8 parts of Panax notoginseng, 1-5 parts of Ginkgo biloba leaf, 1-10 parts of rice vinegar, 3-5 parts of borneol, and 5-10 parts of honey.

3. The traditional Chinese medicine composition for reducing swelling and relieving pain according to claim 2, characterized in that: The raw materials and their weight fractions for making the traditional Chinese medicine composition are as follows: 15 parts of Phellodendron bark, 5 parts of dandelion, 30 parts of gallnut, 2 parts of Patrinia scabiosaefolia, 5 parts of Forsythia suspensa, 5 parts of safflower, 8 parts of Corydalis yanhusuo, 8 parts of Panax notoginseng, 2 parts of Ginkgo biloba leaf, 10 parts of rice vinegar, 5 parts of borneol, and 5 parts of honey.

4. A traditional Chinese medicine composition for reducing swelling and relieving pain according to claim 2, characterized in that: The raw materials and their weight fractions for making the Chinese herbal composition are as follows: 20 parts of Phellodendron bark, 10 parts of dandelion, 40 parts of gallnut, 1 part of Patrinia scabiosaefolia, 4 parts of Forsythia suspensa, 5 parts of safflower, 1 part of Corydalis yanhusuo; 6 parts of Panax notoginseng; 1 part of Ginkgo biloba leaf, 4 parts of rice vinegar, 3 parts of borneol, and 5 parts of honey.

5. A traditional Chinese medicine composition for reducing swelling and relieving pain according to claim 1, characterized in that: The traditional Chinese medicine composition is prepared as a topical ointment.

6. A method for preparing a traditional Chinese medicine composition for reducing swelling and relieving pain, characterized in that, Includes the following steps: S1. Take each of the medicinal materials of any of the weight components in the Chinese herbal composition, mix them and then pulverize them with a pulverizer. The fineness of the powder is 50 mesh. The powder after coarse powdering is pulverized by ultra-micro pulverization technology so that the average particle size of the powder is less than 50 μm. S2. Put the pulverized medicine powder into the heating tank, add 2000-3000mL of water and rice vinegar, and heat at 180℃ for 1 hour while stirring. Extract 200-250mL of the supernatant liquid for later use. S3, 100 mesh filtration, then ultrafiltration through an ultrafiltration column with a molecular weight cutoff of 10000, the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.20-1.25 at 80℃, and then set aside for later use; S4. Add water to the filter residue, heat it a second time, boil for 45-60 minutes, filter, and reserve the filtrate. S5. After mixing the extract and supernatant, add 2-4 times the amount of distilled water and stir well. Heat to boiling for 30 minutes, let stand for 2 hours, extract and filter to obtain filtrate. Fill and seal the filtrate, autoclave at 122℃-125℃ for 20-30 minutes, add borneol, mix well, cool, and the ointment is obtained. Dispense into containers.