Phyllanthus emblica and cistanche tabletting candy capable of invigorating kidney and strengthening yang

Abstract

The invention belongs to the technical field of food processing, and relates to a kidney-tonifying and yang-strengthening emblic leafflower fruit and cistanche tabletting candy, which is prepared from the following raw materials in parts by weight: 10 to 20 parts of emblic leafflower fruit extract, 8 to 15 parts of cistanche extract, 5 to 12 parts of fructus lycii powder, 3 to 8 parts of yam flour, 15 to 25 parts of maltodextrin, 5 to 10 parts of sorbitol and 1 to 3 parts of magnesium stearate. The emblic leafflower fruit and cistanche deserticola tablet candy has the advantages that the emblic leafflower fruit and the cistanche deserticola extract are scientifically matched to synergistically improve the symptom of kidney deficiency, and the emblic leafflower fruit and cistanche deserticola tablet candy is high in safety, good in stability and suitable for long-term taking.

Description

Technical Field

[0001] This invention belongs to the field of food processing technology and relates to a kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola. Background Technology

[0002] With the fast pace of life, increased work pressure, and the influence of unhealthy lifestyle habits, more and more people are experiencing problems such as kidney deficiency, lack of energy, and weakened immunity, leading to a growing market demand for kidney-tonifying and aphrodisiac foods. Currently, there are many types of kidney-tonifying and aphrodisiac foods on the market, mainly including traditional Chinese medicinal herbs, health foods, and functional foods.

[0003] Traditional Chinese medicinal herbs such as ginseng, deer antler, and wolfberry, while possessing certain tonic effects, are inconvenient to take, have a poor taste, and their active ingredients are not easily absorbed by the body. Existing health foods mostly use single medicinal materials or simple compound ingredients as raw materials, resulting in limited efficacy and making it difficult to achieve the ideal kidney-tonifying and aphrodisiac effects. Some functional foods, in pursuit of efficacy, add chemically synthesized ingredients, posing certain safety risks, and also have poor taste and stability, making them inconvenient to carry and take for extended periods.

[0004] Phyllanthus emblica is a plant used both as food and medicine, rich in vitamin C, tannins, phenols, and other active ingredients, possessing antioxidant, immune-boosting, liver-protecting, and kidney-protecting effects. Cistanche deserticola is a traditional Chinese medicine for tonifying the kidneys and strengthening yang, containing active ingredients such as echinacoside and verbascoside, which can tonify kidney yang, nourish essence and blood, and moisten the intestines to relieve constipation. However, there are currently no reports of scientifically combining Phyllanthus emblica and Cistanche deserticola for the preparation of kidney-tonifying and yang-strengthening compressed candies. If these two can be organically combined, along with other tonic excipients, to develop a compressed candy with significant efficacy, good taste, safety, stability, and ease of consumption, it would effectively meet market demand and have important practical significance. Summary of the Invention

[0005] The purpose of this invention is to solve the above problems and provide a kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola.

[0006] To achieve the above objectives, the present invention provides a kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola, which is composed of the following raw materials in parts by weight: 10-20 parts Phyllanthus emblica extract, 8-15 parts Cistanche deserticola extract, 5-12 parts Lycium barbarum powder, 3-8 parts Dioscorea opposita powder, 15-25 parts maltodextrin, 5-10 parts sorbitol, and 1-3 parts magnesium stearate.

[0007] Furthermore, the preparation method of Phyllanthus emblica extract is as follows: fresh Phyllanthus emblica fruits are washed, dried, and pulverized. 6-8 times their weight of 70%-80% ethanol solution is added, and the mixture is refluxed at 60-70℃ for 2-3 times, each time for 2-3 hours. The extracts are combined, concentrated under reduced pressure to a paste with a relative density of 1.10-1.20, and spray-dried to obtain Phyllanthus emblica extract, wherein the total phenol content of Phyllanthus emblica is ≥25%.

[0008] Furthermore, the preparation method of Cistanche deserticola extract is as follows: select dried Cistanche deserticola tubers, pulverize them, add 5-7 times their weight of 60%-70% ethanol solution, and ultrasonically extract at 55-65℃ for 1.5-2.5 hours. Extract twice, combine the extracts, filter, concentrate under reduced pressure until there is no alcohol odor, vacuum dry, and pulverize to obtain Cistanche deserticola extract, wherein the content of echinacoside is ≥15%.

[0009] Furthermore, the wolfberry powder is made from Ningxia wolfberries through washing, drying, and ultra-fine grinding, with a particle size of 80-120 mesh; the yam powder is made from iron yam through peeling, slicing, drying, and grinding, with a particle size of 80-120 mesh.

[0010] A preparation method is also provided, comprising: Raw material pretreatment: Phyllanthus emblica extract, Cistanche deserticola extract, Lycium barbarum powder, Dioscorea opposita powder, maltodextrin, and sorbitol are passed through an 80-100 mesh sieve and set aside. Mixing: According to the weight ratio, add the pretreated Phyllanthus emblica extract, Cistanche deserticola extract, Lycium barbarum powder, Dioscorea opposita powder, maltodextrin and sorbitol into a mixer and mix for 15-25 minutes to obtain a mixed powder; Granulation: Add an appropriate amount of purified water to the mixed powder to adjust the material moisture to 20%-25%, and granulate using a swing granulator with a sieve mesh of 16-20 to obtain wet granules; Drying: Place the wet granules in a hot air circulating drying oven and dry them at 50-60℃ for 2-3 hours, controlling the moisture content of the granules to 3%-5%, to obtain dry granules; Granulation: The dry granules are granulated through a 16-20 mesh sieve to remove fine powder and lumpy particles; Total blending: Add magnesium stearate to the granulated dry granules and mix in a mixer for 5-10 minutes to obtain total blended granules; Tableting: The total mixed granules are put into a tableting machine for tableting, and the tablet weight is controlled at 0.5-1.0g / tablet, and the hardness is 3-5kg to obtain compressed candy; Packaging: The compressed candies are packaged in aluminum-plastic blister packs to obtain the finished product.

[0011] Furthermore, the amount of purified water added during granulation is 10%-15% of the weight of the mixed powder.

[0012] Furthermore, the drying process is carried out in stages, first drying at 50-55℃ for 1-1.5 hours, and then drying at 55-60℃ for 1-1.5 hours.

[0013] The beneficial effects of this invention are as follows: The kidney-tonifying and aphrodisiac compressed candy of Phyllanthus emblica and Cistanche deserticola of the present invention, through the scientific combination of Phyllanthus emblica and Cistanche deserticola extracts (1.2-2.5:1), synergistically improves the symptoms of kidney deficiency, has high safety and good stability, and is suitable for long-term use. Detailed Implementation

[0014] Example 1 A kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola is composed of the following ingredients in parts by weight: 15 parts Phyllanthus emblica extract, 12 parts Cistanche deserticola extract, 8 parts Lycium barbarum powder, 5 parts Dioscorea opposita powder, 20 parts maltodextrin, 8 parts sorbitol, and 2 parts magnesium stearate.

[0015] Its preparation method includes the following steps: (1) Raw material pretreatment: Phyllanthus emblica extract, Cistanche deserticola extract, Lycium barbarum powder, Dioscorea opposita powder, maltodextrin and sorbitol were passed through a 100-mesh sieve and set aside; (2) Mixing: According to the above weight ratio, put the pretreated raw materials into the mixer and mix for 20 minutes to obtain mixed powder; (3) Granulation: Add 12% of purified water by weight of the mixed powder to the mixed powder, adjust the material moisture to 22%, and granulate using a swing granulator (18 mesh screen) to obtain wet granules; (4) Drying: Place the wet granules in a hot air circulating drying oven, dry them at 52°C for 1.2 hours, and then at 58°C for 1.3 hours, controlling the moisture content of the granules to 4% to obtain dry granules; (5) Granulation: The dry granules are granulated using an 18-mesh sieve; (6) Total mixing: Add magnesium stearate to the granulated dry granules and mix in a mixer for 8 minutes to obtain total mixed granules; (7) Tableting: The total mixed granules are put into the tableting machine, and the tablet weight is controlled at 0.8g / tablet and the hardness is 4kg to obtain compressed candy; (8) Packaging: Pack the compressed candy in aluminum-plastic blister packaging to obtain the finished product.

[0016] Example 2 A kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola is composed of the following ingredients in parts by weight: 10 parts Phyllanthus emblica extract, 8 parts Cistanche deserticola extract, 5 parts Lycium barbarum powder, 3 parts Dioscorea opposita powder, 15 parts maltodextrin, 5 parts sorbitol, and 1 part magnesium stearate.

[0017] Its preparation method includes the following steps: (1) Raw material pretreatment: Phyllanthus emblica extract, Cistanche deserticola extract, Lycium barbarum powder, Dioscorea opposita powder, maltodextrin and sorbitol were passed through an 80-mesh sieve and set aside. (2) Mixing: According to the above weight ratio, put the pretreated raw materials into the mixer and mix for 15 minutes to obtain mixed powder; (3) Granulation: Add 10% of purified water by weight of the mixed powder to the mixed powder, adjust the material moisture to 20%, and granulate using a swing granulator (16 mesh screen) to obtain wet granules; (4) Drying: Place the wet granules in a hot air circulating drying oven, dry them at 50°C for 1 hour, and then at 55°C for 1 hour, controlling the moisture content of the granules to 3% to obtain dry granules; (5) Granulation: The dry granules are granulated using a 16-mesh sieve; (6) Total mixing: Add magnesium stearate to the granulated dry granules and mix in a mixer for 5 minutes to obtain total mixed granules; (7) Tableting: The total mixed granules are put into a tableting machine, and the tablet weight is controlled at 0.5g / tablet and the hardness is 3kg to obtain compressed candy; (8) Packaging: Pack the compressed candy in aluminum-plastic blister packaging to obtain the finished product.

[0018] Example 3 A kidney-tonifying and aphrodisiac compressed candy made from Phyllanthus emblica and Cistanche deserticola is composed of the following ingredients in parts by weight: 20 parts Phyllanthus emblica extract, 15 parts Cistanche deserticola extract, 12 parts Lycium barbarum powder, 8 parts Dioscorea opposita powder, 25 parts maltodextrin, 10 parts sorbitol, and 3 parts magnesium stearate.

[0019] Its preparation method includes the following steps: (1) Raw material pretreatment: Phyllanthus emblica extract, Cistanche deserticola extract, Lycium barbarum powder, Dioscorea opposita powder, maltodextrin and sorbitol were passed through a 100-mesh sieve and set aside; (2) Mixing: According to the above weight ratio, put the pretreated raw materials into the mixer and mix for 25 minutes to obtain mixed powder; (3) Granulation: Add 15% of purified water by weight of the mixed powder to the mixed powder, adjust the material moisture to 25%, and granulate using a swing granulator (20 mesh screen) to obtain wet granules; (4) Drying: Place the wet granules in a hot air circulating drying oven, dry them at 55°C for 1.5 hours, and then at 60°C for 1.5 hours, controlling the moisture content of the granules to 5% to obtain dry granules; (5) Granulation: The dry granules are granulated using a 20-mesh sieve; (6) Total mixing: Add magnesium stearate to the granulated dry granules and mix in a mixer for 10 minutes to obtain total mixed granules; (7) Tableting: The total mixed granules are put into a tableting machine, and the tablet weight is controlled at 1.0g / tablet and the hardness is 5kg to obtain compressed candy; (8) Packaging: Pack the compressed candy in aluminum-plastic blister packaging to obtain the finished product.

[0020] Effect verification experiment To verify the kidney-tonifying and aphrodisiac effects of the compressed candy of this invention, 60 volunteers with symptoms of kidney deficiency such as lower back and knee pain, lack of energy, and decreased sexual function were randomly divided into 3 groups of 20 each. Each group took the compressed candy prepared according to Examples 1, 2, and 3 of this invention, twice daily, 2 tablets each time, for 30 consecutive days. During the experiment, the volunteers maintained normal diet and rest, and avoided taking other tonic products.

[0021] Efficacy evaluation criteria Significant effect: Core symptoms such as lower back and knee pain, lack of energy, and decreased sexual function disappear or improve by ≥80%, resulting in abundant energy in daily work and life, and no discomfort. Effective: Core symptoms improved by 30%-79%, energy was restored, the quality of sexual life was significantly improved compared to before the experiment, and there was occasional mild abdominal bloating (which was relieved on its own after stopping the medication). Ineffective: The improvement of core symptoms is less than 30%, or the symptoms do not change or even worsen, with obvious discomfort such as fever and constipation.

[0022] Group Effective (person) Effective (person) Invalid (person) Overall effectiveness (%) Number of people experiencing mild discomfort Example 1 12 7 1 95 0 Example 2 8 10 2 90 1 (Mild abdominal bloating, relieved after 1 day) Example 3 13 6 1 95 0 control group 0 2 18 10 0 The control group consisted of 20 volunteers of the same type who took placebo tablets without Phyllanthus emblica extract or Cistanche deserticola extract (the raw materials were 25 parts maltodextrin, 8 parts sorbitol, and 2 parts magnesium stearate, and the preparation process was the same as in Example 1). The administration method and cycle were the same as in the experimental group.

[0023] Experimental conclusion: Significant efficacy: The total effective rates of groups 1-3 in Examples were 95%, 90%, and 95%, respectively, which were much higher than the 10% of the control group. The significant efficacy rates of groups 1 and 3 in Examples were 60% and 65%, respectively, indicating that the compressed candy of the present invention can effectively improve symptoms such as soreness and weakness of the waist and knees, lack of energy, and decreased sexual function caused by kidney deficiency. Moreover, the ratio of the core active ingredients (Phyllanthus amla extract and Cistanche deserticola extract) has a direct impact on efficacy. When the ratio of Phyllanthus amla extract to Cistanche deserticola extract is 15-20 parts and the ratio of Cistanche deserticola extract to 12-15 parts, the significant efficacy rate is higher. This is consistent with the previous conclusion that "the synergistic effect is best when the weight ratio of Phyllanthus amla extract to Cistanche deserticola extract is 1.2-2.5:1".

[0024] Safety: Only one case of mild abdominal distension occurred in the second example group (accounting for 5% of the group), which was relieved spontaneously within a short period of time. No adverse reactions were observed in the other experimental groups. This indicates that the compressed candy of the present invention, by using yam powder to balance the nourishing and greasy nature of Cistanche deserticola, effectively reduces the side effects such as internal heat and constipation that are easily caused by traditional kidney-tonifying products. It has a high safety profile and is suitable for long-term use.

[0025] Synergistic effect of excipients: Comparison between the experimental group and the control group shows that the addition of wolfberry powder and yam powder not only did not affect the core efficacy, but also further improved the overall conditioning effect through the synergistic effect of "nourishing the liver and kidneys + tonifying the spleen and kidneys", while improving the taste of the product (the volunteers in the experimental group reported that the taste was slightly sweet and there was no obvious bitter taste of Chinese medicine, while the taste of the control group was monotonous).

[0026] In addition, to verify the product stability, an accelerated stability test was conducted on the compressed candy prepared in Example 1 (temperature 40℃±2℃, relative humidity 75%±5%, sealed storage for 6 months). The results showed that the product appearance did not change color, absorb moisture, or crack, and the hardness was maintained at 3.8-4.2kg (meeting the quality standard of 3-5kg). The total phenol content retention rate of amla was ≥92%, and the echinacea glycoside content retention rate was ≥90%, indicating that the compressed candy of the present invention has good physical stability and active ingredient stability, and can meet the requirements for long-term storage.

[0027] The above description is merely one embodiment of the present invention and is not intended to limit the invention. Those skilled in the art will recognize that the present invention can be modified and varied in various ways. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A kidney-tonifying and aphrodisiac compressed candy containing Phyllanthus emblica and Cistanche deserticola, characterized in that... It is composed of the following raw materials in parts by weight: 10-20 parts of Phyllanthus emblica extract, 8-15 parts of Cistanche deserticola extract, 5-12 parts of Lycium barbarum powder, 3-8 parts of Dioscorea opposita powder, 15-25 parts of maltodextrin, 5-10 parts of sorbitol and 1-3 parts of magnesium stearate.

2. The kidney-tonifying and aphrodisiac compound candy containing Phyllanthus emblica and Cistanche deserticola according to claim 1, characterized in that, The preparation method of Phyllanthus emblica extract is as follows: fresh Phyllanthus emblica fruits are washed, dried and pulverized, and 6-8 times their weight of 70%-80% ethanol solution is added. The mixture is refluxed at 60-70℃ for 2-3 times, each time for 2-3 hours. The extracts are combined and concentrated under reduced pressure to a paste with a relative density of 1.10-1.

20. The paste is then spray-dried to obtain Phyllanthus emblica extract, wherein the total phenol content of Phyllanthus emblica is ≥25%.

3. The kidney-tonifying and aphrodisiac compound candy containing Phyllanthus emblica and Cistanche deserticola according to claim 2, characterized in that, The preparation method of Cistanche deserticola extract is as follows: Select dried Cistanche deserticola tubers, pulverize them, add 5-7 times their weight of 60%-70% ethanol solution, and extract by ultrasonication at 55-65℃ for 1.5-2.5 hours. Extract twice, combine the extracts, filter, concentrate under reduced pressure until there is no alcohol odor, vacuum dry, and pulverize to obtain Cistanche deserticola extract, in which the echinacoside content is ≥15%.

4. The kidney-tonifying and aphrodisiac compound candy containing Phyllanthus emblica and Cistanche deserticola according to claim 3, characterized in that, The goji berry powder is made from Ningxia goji berries through washing, drying, and ultra-fine grinding, with a particle size of 80-120 mesh; the yam powder is made from iron yam through peeling, slicing, drying, and grinding, with a particle size of 80-120 mesh.