Third-order targeted yang-warming and kidney-tonifying composition as well as preparation method and application thereof
By utilizing a three-stage targeted warming and kidney-tonifying composition, and taking advantage of the synergistic effect of rapid activation, intermediate-acting consolidation, and long-acting nourishment, this product rapidly improves men's sub-health status, solving the problems of slow onset of action and rebound after discontinuation of existing products, and achieving significant long-term effects.
Patent Information
- Application Number
- CN202610366391.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-24
- Publication Date
- 2026-05-15
AI Technical Summary
Existing male kidney tonics suffer from slow onset of action, difficulty in maintaining the regimen, and rebound effects after discontinuation, making it difficult to effectively improve men's sub-health status.
The formula employs a three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition. These compositions are composed of ingredients such as deer antler peptide, epimedium extract, and clove extract. Through the synergistic effect of different stages, the formula rapidly activates kidney yang, tonifies both yin and yang, and replenishes essence and marrow, achieving a progressive conditioning effect.
Within 1-2 treatment cycles, it significantly improves symptoms such as fatigue, lower back and knee pain, and aversion to cold, with stable effects for more than three months. It solves the problems of slow onset of action and rebound after discontinuation of medication, with a total improvement rate of 93.3%.
Smart Images
Figure SMS_1 
Figure SMS_2 
Figure SMS_3
Abstract
Description
Technical Field
[0001] This invention belongs to the field of health product technology, specifically relating to a three-stage targeted warming and kidney-tonifying composition, its preparation method, and its application. Background Technology
[0002] The fast pace and high pressure of modern life, coupled with unhealthy lifestyle habits, have led to a sub-healthy state for many men, manifesting as lack of energy, lower back and knee pain, cold limbs, and fatigue. Traditional Chinese medicine theory often attributes this to kidney yang deficiency and insufficient essence and blood. Currently, the market is flooded with products claiming to tonify the kidneys for men, but most suffer from two major drawbacks: firstly, they are slow to take effect, often requiring 1-3 months of continuous use before users experience any noticeable changes, making it difficult to maintain consistency; secondly, the effects are not lasting, with rapid decline and rebound after discontinuation. In view of this, this invention is proposed. Summary of the Invention
[0003] In view of the shortcomings of the prior art, the technical problem to be solved by the present invention is to provide a three-stage targeted warming and kidney-tonifying composition that can effectively improve the sub-health status of men.
[0004] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is: a three-stage targeted warming and kidney-tonifying composition, which consists of a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition. The effective components of the fast-acting activating composition include deer antler peptide, epimedium extract, and clove extract. The effective components of the medium-acting consolidation composition include cistanche tubulosa extract, cuscuta chinensis extract, mulberry extract, wolfberry extract, and angelica sinensis extract. The effective components of the long-acting nourishing composition include rehmannia glutinosa extract, prepared polygonum multiflorum extract, euryale ferox extract, walnut peptide, black sesame extract, and morinda officinalis extract.
[0005] The fast-acting activating composition uses deer antler peptide as the principal ingredient to tonify kidney yang and replenish essence and blood; epimedium extract as the assistant ingredient to warm and unblock the kidney meridian, stimulate internal yang qi, and enhance efficacy; and clove extract as the adjuvant ingredient to warm the middle jiao, dispel cold, promote qi circulation, and facilitate absorption. These three ingredients work synergistically to quickly activate kidney yang, addressing the issue of slow onset of action. The medium-acting consolidation composition uses cistanche tubulosa extract and dodder seed extract as the principal ingredients to achieve dual yin and yang tonification; mulberry extract and wolfberry extract as the assistant ingredients to nourish yin and blood, strengthening and consolidating the effect; and angelica extract as the adjuvant ingredient to promote smooth qi and blood flow, synergistically consolidating kidney yang while replenishing essence and blood, addressing the issue of tonification without effective consolidation. The long-acting nourishing composition uses rehmannia glutinosa extract and prepared polygonum multiflorum extract as the principal ingredients to replenish essence and marrow; euryale ferox extract as the assistant ingredient to strengthen the kidneys and astringe essence; walnut peptide and black sesame extract as the adjuvant ingredients to tonify the kidneys and invigorate the brain; and morinda officinalis extract as the adjuvant ingredient to gently promote metabolism, synergistically replenish essence and marrow, repair the root cause, and address the issue of rebound after discontinuation of treatment. The above three stages work together organically, with both micro-level synergy within each stage and macro-level temporal synergy between the three stages, forming a complete and dynamic conditioning system.
[0006] Optionally, the fast-acting activating composition contains 0.4-1.6 parts by weight of deer antler peptide, 1-12 parts by weight of epimedium extract, and 0.2-1 parts by weight of clove extract. The content of epimedium glycoside in the epimedium extract is ≥1.2%.
[0007] Optionally, the medium-efficacy consolidation composition contains 0.5-1 parts by weight of Cistanche tubulosa extract, 2-8 parts by weight of Cuscuta chinensis extract, 1-6 parts by weight of Morus alba extract, 1-6 parts by weight of Lycium barbarum extract, and 0.5-3 parts by weight of Angelica sinensis extract. The content of echinacoside in the extract of Cistanche tubulosa is ≥1.0%.
[0008] Optionally, the long-acting nourishing composition contains 2-12 parts by weight of Rehmannia glutinosa extract, 0.5-16 parts by weight of Polygonum multiflorum extract, 0.5-12 parts by weight of Euryale ferox extract, 0.2-8 parts by weight of walnut peptide, 1-6 parts by weight of black sesame extract, and 0.5-4 parts by weight of Morinda officinalis extract.
[0009] Optionally, the fast-acting activating composition can be prepared into fast-acting dosage forms such as sublingual granules, orally disintegrating tablets, and sprays, preferably sublingual granules, each weighing 0.2-1g; The medium-efficacy consolidation composition can be prepared into conventional dosage forms such as granules, tablets, and capsules, preferably granules, each weighing 18g. The long-acting nourishing composition can be prepared into sustained-release dosage forms such as sustained-release pills, sustained-release tablets, and implants, preferably sustained-release pills, each weighing 6g.
[0010] Without altering the raw material composition of this invention, those skilled in the art can choose dry granulation, wet granulation, direct tableting, melt molding, or other conventional pharmaceutical techniques to prepare sublingual, oral infusion, and sustained-release dosage forms, all of which are expected to achieve the intended preparation.
[0011] Optionally, the sublingual granules of the fast-acting activating composition may further contain excipients: 0.05-1 parts by weight of menthol and 0.5-2 parts by weight of fructooligosaccharides.
[0012] Optionally, the infusion granules of the medium-strengthening composition may further contain auxiliary ingredients: 0.5-3 parts by weight of yam and 0.5-3 parts by weight of honey.
[0013] Optionally, the sustained-release pills of the long-acting nourishing composition may further contain excipients: 0.5-4 parts by weight of Poria cocos and 0.2-2 parts by weight of maltitol.
[0014] Optionally, the three-stage targeted warming and kidney-tonifying composition is packaged as a conditioning cycle, the package containing: 3 units of the fast-acting activating composition, 4 units of the medium-acting consolidation composition, and at least 14 units of the long-acting nourishing composition.
[0015] A method for preparing the above-mentioned three-stage targeted warming and kidney-tonifying composition includes: Sublingual granules of the fast-acting activating composition, infusion granules of the intermediate-acting consolidation composition, and sustained-release pills of the long-acting nourishing composition were prepared separately. The three prepared compositions were packaged according to the dosage for one conditioning cycle.
[0016] Among them, sublingual granules are prepared by dry granulation, infusion granules are prepared by wet granulation, and sustained-release pills are prepared by melt molding.
[0017] The application of the above-mentioned three-stage targeted warming and kidney-tonifying composition in the preparation of a medicinal and edible dietary supplement for improving male sub-health conditions. This product is a medicinal and edible dietary supplement, not a drug, and cannot replace drug treatment.
[0018] In response to the problems raised in the background technology, the industry's common practice is to adjust the types or dosages of medicinal materials in a single formula. For example, CN106334041A discloses a male external aphrodisiac composition of deer antler polypeptide, and CN104887980B discloses a traditional Chinese medicine composition for kidney deficiency, both attempting to explore a solution that can achieve both rapid and long-term stability. However, this one-size-fits-all approach may fall into the contradiction of rapid tonification leading to intolerance of the body's deficiencies, and gentle tonification resulting in slow effects. Therefore, a new conditioning logic is urgently needed to overcome this contradiction and better address the issue of male sub-health conditioning.
[0019] Compared with the prior art, the beneficial effects of the present invention are as follows: This invention proposes a three-stage targeted warming and kidney-tonifying composition, consisting of a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition. These are used sequentially, moving beyond the single-formula approach and incorporating the principles of time-based therapy. Through this three-stage design—fast-acting activation, medium-acting consolidation, and long-acting nourishment—it addresses three core issues: kidney yang deficiency, insufficient essence and blood, and weak kidney essence, progressively enhancing efficacy. Clinical trials have shown that this invention significantly improves overall symptoms such as fatigue, lower back and knee weakness, and cold intolerance within 1-2 treatment cycles compared to single-formula compositions.
[0020] In the rapid-acting activating composition of this invention, deer antler peptides are absorbed directly through the sublingual vein without requiring gastrointestinal digestion, quickly entering the bloodstream and stimulating kidney yang. Icariin targets the kidney meridian, and combined with clove extract, it warms and unblocks the meridians, significantly improving symptoms such as aversion to cold and morning lethargy within three days. In the medium-acting consolidation composition, Cistanche deserticola and Cuscuta chinensis extracts warm and tonify kidney yang without causing heat, while mulberry and wolfberry extracts nourish kidney yin, achieving a dual tonification of yin and yang. Angelica sinensis extract invigorates blood circulation, addressing the issue of insufficient flow after tonification, improving symptoms such as lower back and knee weakness and decreased bodily function within four days. In the long-acting nourishing composition, Rehmannia glutinosa extract and Polygonum multiflorum extract replenish essence and marrow, addressing the root cause of kidney essence deficiency; walnut peptides and black sesame extract supplement the brain and kidneys with nutrients from the same source, combined with Euryale ferox extract to strengthen the kidneys and astringe essence; Morinda officinalis extract gently warms yang, and long-term use can improve symptoms such as fatigue and difficulty maintaining energy, with stable effects lasting for more than three months.
[0021] This invention provides optimal dosage forms for different stages: The first stage consists of sublingual granules, utilizing the rich sublingual venous plexus to avoid the first-pass effect of the liver, allowing small-molecule active ingredients such as deer antler peptides to quickly enter the bloodstream, with effects felt within minutes, addressing the issue of slow onset of action. The second stage consists of infused granules, facilitating large-dose replenishment of the complex ingredients that nourish both essence and blood, and are easily absorbed. The third stage consists of sustained-release pills, using sustained-release coating technology to allow the active ingredients to be released slowly and persistently in the body, providing gentle nourishment and achieving the long-term goal of replenishing essence and marrow, strengthening the body's foundation, and solving the problem of rebound effects after discontinuation. This product needs to be taken in the order of the stages. Detailed Implementation
[0022] To better understand the present invention, the following embodiments further illustrate the content of the invention, but the scope of protection of the present invention is not limited to the following embodiments. Numerous specific details are set forth in the following description to provide a more thorough understanding of the invention. However, it will be apparent to those skilled in the art that the present invention can be practiced without one or more of these details.
[0023] To make the objectives and advantages of the present invention clearer, the following detailed description, in conjunction with specific embodiments, provides a further detailed explanation of the three-stage targeted warming and kidney-tonifying composition, its preparation method, its application, and its technical effects. It should be understood that the specific embodiments described herein are merely illustrative of the invention and should not be construed as limiting the invention. Unless otherwise specified, the following embodiments do not include components other than unavoidable impurities. Unless otherwise specified, the raw materials used in the embodiments are commercially available. Experimental methods not specified in the embodiments are implemented under conventional conditions, such as those described in literature, books, or methods recommended by the manufacturer.
[0024] Deer antler peptide is derived from the unossified, densely haired young antlers of male red deer, with a peptide content ≥98%; Epimedium extract is derived from the dried aerial parts of Epimedium (Berberis thunbergii), with an epimedin content ≥1.2%; Clove extract is derived from the dried flower buds of Clove (Syzygium aromaticum), Myrtaceae; Cistanche tubulosa extract is derived from the dried fleshy stems with scaly leaves of Cistanche deserticola (Orobanche deserticola), with an echinacoside content ≥1.0%; Cuscuta chinensis extract is derived from the dried mature seeds of Cuscuta chinensis (Convolvulaceae); Mulberry extract is derived from the dried fruit spikes of Morus alba (Morus alba), Moraceae; and Lycium barbarum extract is derived from Solanaceae. The ingredients are: dried, mature fruit of *Lycium barbarum* (Ningxia wolfberry); Angelica sinensis extract derived from the dried root of *Angelica sinensis* (Apiaceae); Rehmannia glutinosa extract derived from the dried tuberous root of *Rehmannia glutinosa* (Scrophulariaceae); Polygonum multiflorum extract derived from the dried tuberous root of *Polygonum multiflorum* (Polygonaceae); Euryale ferox extract derived from the dried, mature seed kernel of *Euryale ferox* (Nymphaeaceae); walnut peptide derived from the dried, mature seed of *Juglans regia* (Juglans regia), with a peptide content ≥85%; black sesame extract derived from the dried, mature seed of *Sesamum indicum* (Pedaliaceae); and Morinda officinalis extract derived from the dried root of *Morinda officinalis* (Rubiaceae). All the above ingredients are commercially available 10:1 extracts, and all are in powder form.
[0025] Example 1: A three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition; The fast-acting activating composition is made from the following raw materials: 1.0 part by weight of deer antler peptide, 6 parts by weight of epimedium extract, 0.6 parts by weight of clove extract, 0.5 parts by weight of menthol and 1.2 parts by weight of fructooligosaccharides; The intermediate-strengthening composition is made from the following raw materials: 0.8 parts by weight of Cistanche tubulosa extract, 5 parts by weight of Cuscuta chinensis extract, 3 parts by weight of mulberry extract, 3 parts by weight of wolfberry extract, 1.8 parts by weight of Angelica sinensis extract, 1.7 parts by weight of yam powder, and 1.8 parts by weight of honey; The long-lasting nourishing composition is made from the following raw materials: 7 parts by weight of Rehmannia glutinosa extract, 8 parts by weight of Polygonum multiflorum extract, 6 parts by weight of Euryale ferox extract, 4 parts by weight of walnut peptide, 4 parts by weight of black sesame extract, 2 parts by weight of Morinda officinalis extract, 2 parts by weight of Poria cocos powder, and 1.1 parts by weight of maltitol.
[0026] The preparation method of the above-mentioned three-stage targeted warming and kidney-tonifying composition includes: Mix all the raw materials of the fast-acting activating composition evenly, add 0.5% magnesium stearate, and dry granulate to make 0.6g / capsule sublingual granules; The raw materials of the medium-efficiency consolidation composition are mixed with 35% lactose, 10% sucrose and 2% citric acid, wet granulated, dried and packaged into 18g / packet instant granules. Mix the ingredients of the long-acting nourishing composition with 20% beeswax, melt and mold to make 6g / pill sustained-release pills.
[0027] The three prepared compositions were packaged according to the dosage for one conditioning cycle.
[0028] The percentages mentioned above are all by weight, representing the percentage of each excipient in the total weight of the raw materials in the corresponding composition.
[0029] One treatment cycle package contains: 3 units of fast-acting activating composition, 4 units of medium-acting consolidation composition, and 14 units of long-acting nourishing composition.
[0030] Example 2: A three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition; differing from Example 1 in that: The fast-acting activating composition is made from the following raw materials: 0.4 parts by weight of deer antler peptide, 1 part by weight of epimedium extract, 0.2 parts by weight of clove extract, 0.05 parts by weight of menthol, and 0.5 parts by weight of fructooligosaccharide; it is made into granules, each granule weighing 1g (i.e., one unit), and is taken sublingually. The intermediate-acting consolidation composition is made from the following raw materials: 0.5 parts by weight of Cistanche tubulosa extract, 2 parts by weight of Cuscuta chinensis extract, 1 part by weight of mulberry extract, 1 part by weight of wolfberry extract, 0.5 parts by weight of Angelica sinensis extract, 0.5 parts by weight of yam powder, and 0.5 parts by weight of honey; it is made into granules, each packet weighing 18g (i.e., one unit); it is taken by brewing. The long-acting nourishing composition is made from the following raw materials: 2 parts by weight of Rehmannia glutinosa extract, 0.5 parts by weight of Polygonum multiflorum extract, 0.5 parts by weight of Euryale ferox extract, 0.2 parts by weight of walnut peptide, 1 part by weight of black sesame extract, 0.5 parts by weight of Morinda officinalis extract, 0.5 parts by weight of Poria cocos powder, and 0.2 parts by weight of maltitol; it is made into sustained-release pills, each weighing 6g (i.e., one unit).
[0031] Example 3: A three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition; differing from Example 1 in that: The fast-acting activating composition is made from the following raw materials: 1.6 parts by weight of deer antler peptide, 12 parts by weight of epimedium extract, 1 part by weight of clove extract, 1 part by weight of menthol, and 2 parts by weight of fructooligosaccharides; it is made into granules, each weighing 0.2g (i.e., one unit), and is taken sublingually. The intermediate-acting consolidation composition is made from the following raw materials: 1 part by weight of Cistanche tubulosa extract, 8 parts by weight of Cuscuta chinensis extract, 6 parts by weight of Morus alba extract, 6 parts by weight of Lycium barbarum extract, 0.5-3 parts by weight of Angelica sinensis extract, 0.5-3 parts by weight of Dioscorea opposita powder, and 0.5-3 parts by weight of honey; it is made into granules, each packet weighing 18g (i.e., one unit); it is taken by brewing. The long-acting nourishing composition is made from the following raw materials: 12 parts by weight of Rehmannia glutinosa extract, 16 parts by weight of Polygonum multiflorum extract, 12 parts by weight of Euryale ferox extract, 8 parts by weight of walnut peptide, 6 parts by weight of black sesame extract, 4 parts by weight of Morinda officinalis extract, 4 parts by weight of Poria cocos powder, and 2 parts by weight of maltitol; it is made into sustained-release pills, each weighing 6g (i.e., one unit).
[0032] Example 4: A three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition; differing from Example 1 in that: The fast-acting activating composition is made from the following raw materials: 0.7 parts by weight of deer antler peptide, 4 parts by weight of epimedium extract, 0.4 parts by weight of clove extract, 0.25 parts by weight of menthol, and 0.8 parts by weight of fructooligosaccharides; The intermediate-strengthening composition is made from the following raw materials: 0.6 parts by weight of Cistanche tubulosa extract, 5 parts by weight of Cuscuta chinensis extract, 2 parts by weight of mulberry extract, 2 parts by weight of wolfberry extract, 1.1 parts by weight of Angelica sinensis extract, 1.1 parts by weight of yam powder, and 1.1 parts by weight of honey; The long-lasting nourishing composition is made from the following raw materials: 4 parts by weight of Rehmannia glutinosa extract, 4 parts by weight of Polygonum multiflorum extract, 3.5 parts by weight of Euryale ferox extract, 2.1 parts by weight of walnut peptide, 2 parts by weight of black sesame extract, 1.2 parts by weight of Morinda officinalis extract, 1.3 parts by weight of Poria cocos powder, and 0.6 parts by weight of maltitol.
[0033] Example 5: A three-stage targeted warming and kidney-tonifying composition, comprising a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition; differing from Example 1 in that: The fast-acting activating composition is made from the following raw materials: 2.3 parts by weight of deer antler peptide, 9 parts by weight of epimedium extract, 0.8 parts by weight of clove extract, 0.7 parts by weight of menthol, and 1.6 parts by weight of fructooligosaccharides; The intermediate-strengthening composition is made from the following raw materials: 0.9 parts by weight of Cistanche tubulosa extract, 7 parts by weight of Cuscuta chinensis extract, 5 parts by weight of mulberry extract, 5 parts by weight of wolfberry extract, 2.4 parts by weight of Angelica sinensis extract, 2.5 parts by weight of yam powder, and 2.4 parts by weight of honey; The long-lasting nourishing composition is made from the following raw materials: 9 parts by weight of Rehmannia glutinosa extract, 12 parts by weight of processed Polygonum multiflorum extract, 9.5 parts by weight of Euryale ferox extract, 6 parts by weight of walnut peptide, 4.5 parts by weight of black sesame extract, 3 parts by weight of Morinda officinalis extract, 3.2 parts by weight of Poria cocos powder, and 1.6 parts by weight of maltitol.
[0034] Comparative Example 1: The difference from Example 1 is that only the fast-acting activating composition was selected.
[0035] Comparative Example 2: The difference from Example 1 is that only the medium-strength consolidation composition was selected.
[0036] Comparative Example 3: The difference from Example 1 is that only a long-lasting nourishing composition was selected.
[0037] The following provides a detailed explanation of the relevant experimental content for effect evaluation.
[0038] 1. General information of the subjects This trial included 120 eligible male participants, aged 28–55 years, with a mean age of 40.6 ± 5.3 years. All participants exhibited sub-health conditions such as lack of energy, lower back and knee pain, cold limbs, and fatigue. They were randomly divided into four groups, with 30 participants in each group. Statistical analysis showed no significant differences in baseline data such as age, physical condition, and lifestyle habits among the groups (P > 0.05), indicating comparability.
[0039] 2. Subject inclusion criteria 2.1 Inclusion criteria (1) Adult males, aged 28 to 55 years; (2) Having sub-health symptoms related to kidney yang deficiency, including decreased energy, soreness and weakness of the waist and knees, fear of cold, fatigue and weakness, and poor sleep quality; (3) Willing to participate in this observation, able to take the medication as required and cooperate with the recording; (4) No other similar food and medicine conditioning products have been taken in the past month.
[0040] 2.2 Exclusion Criteria (1) Those suffering from serious organic diseases of the heart, liver, kidneys, endocrine system, etc.; (2) Individuals who are allergic to or have an allergic constitution to any of the ingredients in this product formulation; (3) Those who have used other conditioning products or hormone products within the past month; (4) Those with poor compliance who are unable to complete the entire observation period.
[0041] 3. How to use Experimental group: The three-stage targeted warming and kidney-tonifying composition prepared in Example 1 was administered, wherein the fast-acting activating composition was taken 1 capsule daily before bedtime for 3 consecutive days starting from day 1; the intermediate-acting consolidation composition was taken 1 packet daily after breakfast for 4 consecutive days starting from day 4; and the long-acting nourishing composition was taken 1 pill daily after dinner for 14 consecutive days starting from day 8. One cycle (21 days) was administered according to the above method.
[0042] Control groups 1-3: Each group was given the same single-component formula as the experimental group in terms of dosage, frequency of administration, route of administration, and observation period.
[0043] Both groups maintained normal diet and rest during the observation period and did not use any other conditioning products.
[0044] 4. Scoring Method A quantitative scoring method for sub-health status was used to comprehensively score energy level, lower back and knee comfort, cold intolerance, fatigue level, and sleep quality. Each indicator was graded as mild, moderate, or severe with a score of 3, 6, or 9, respectively, as shown in Table 1.
[0045] Table 1 Grading and Quantification Table 5. Efficacy criteria The calculation formula is: Score decline rate = [(Initial quantitative score - Quantitative score at the end of observation) / Initial quantitative score] × 100%; (1) Significant improvement: score reduction rate ≥70%; (2) Improvement: The rate of score reduction was 30% to 70%; (3) No improvement: score decline rate <30%.
[0046] 6. Comparison Table of Treatment Effects (1) The statistical results of the improvement rate of each indicator are shown in Table 2.
[0047] Table 2. Statistical results of improvement rate for a single indicator Note: Improvement rate of a single indicator = (Number of cases with significant improvement in a single indicator + Number of cases with some improvement in a single indicator) / Total number of cases × 100%.
[0048] As shown in Table 2, the improvement rate of the three-stage targeted composition of the present invention for each single indicator is above 85%, while the performance of single-component formulations for each single indicator is significantly inferior to that of the present invention.
[0049] (2) The overall improvement statistics are shown in Table 3.
[0050] Table 3 Overall Improvement Statistics Note: Overall improvement rate = (Number of cases with significant improvement in overall indicators + Number of cases with some improvement in overall indicators) / Total number of cases × 100%.
[0051] As shown in Table 3, the experimental group that took the three-stage targeted warming and kidney-tonifying composition of the present invention had a total improvement rate of 93.3% in sub-health status, which was significantly better than the control group that took the single formula, and the difference was statistically significant (P<0.05).
[0052] The three-stage targeted warming and kidney-tonifying composition of this invention adopts a three-stage compatibility system. Through multi-target, multi-pathway, and multi-level synergistic effects, it has technical advantages over single-component formulas, such as higher absorption rate, faster onset of action, stronger effect, longer duration of action, and better safety. The overall efficacy is 1.5 to 3 times higher than that of single-component formulas, with significant effects.
[0053] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Any other modifications or equivalent substitutions made by those skilled in the art to the technical solutions of the present invention, as long as they do not depart from the spirit and scope of the technical solutions of the present invention, should be covered within the scope of the claims of the present invention.
Claims
1. A three-stage targeted warming and kidney-tonifying composition, characterized in that: The product comprises a fast-acting activating composition, a medium-acting consolidation composition, and a long-acting nourishing composition. The active ingredients of the fast-acting activating composition include deer antler peptide, epimedium extract, and clove extract. The active ingredients of the medium-acting consolidation composition include cistanche tubulosa extract, cuscuta chinensis extract, mulberry extract, wolfberry extract, and angelica sinensis extract. The active ingredients of the long-acting nourishing composition include rehmannia glutinosa extract, prepared polygonum multiflorum extract, euryale ferox extract, walnut peptide, black sesame extract, and morinda officinalis extract.
2. The three-stage targeted warming and kidney-tonifying composition as described in claim 1, characterized in that: The fast-acting activating composition contains 0.4-1.6 parts by weight of deer antler peptide, 1-12 parts by weight of epimedium extract, and 0.2-1 parts by weight of clove extract.
3. The three-stage targeted warming and kidney-tonifying composition as described in claim 2, characterized in that: The medium-efficacy consolidation composition contains 0.5-1 parts by weight of Cistanche tubulosa extract, 2-8 parts by weight of Cuscuta chinensis extract, 1-6 parts by weight of Morus alba extract, 1-6 parts by weight of Lycium barbarum extract, and 0.5-3 parts by weight of Angelica sinensis extract.
4. The three-stage targeted warming and kidney-tonifying composition as described in claim 3, characterized in that: The long-acting nourishing composition contains 2-12 parts by weight of Rehmannia glutinosa extract, 0.5-16 parts by weight of Polygonum multiflorum extract, 0.5-12 parts by weight of Euryale ferox extract, 0.2-8 parts by weight of walnut peptide, 1-6 parts by weight of black sesame extract, and 0.5-4 parts by weight of Morinda officinalis extract.
5. The three-stage targeted warming and kidney-tonifying composition as described in claim 4, characterized in that: The fast-acting activating composition is a sublingual granule; the medium-acting consolidation composition is an infusion granule; and the long-acting nourishing composition is a sustained-release pill.
6. The three-stage targeted warming and kidney-tonifying composition as described in claim 5, characterized in that: The fast-acting activating composition also contains auxiliary ingredients: 0.05-1 parts by weight of menthol and 0.5-2 parts by weight of fructooligosaccharides.
7. The three-stage targeted warming and kidney-tonifying composition as described in claim 5, characterized in that: The intermediate-strengthening composition also contains auxiliary ingredients: 0.5-3 parts by weight of yam and 0.5-3 parts by weight of honey.
8. The three-stage targeted warming and kidney-tonifying composition as described in claim 5, characterized in that: The long-acting nourishing composition also contains auxiliary ingredients: 0.5-4 parts by weight of Poria cocos and 0.2-2 parts by weight of maltitol.
9. A method for preparing a three-stage targeted warming and kidney-tonifying composition according to any one of claims 1-8, characterized in that: include: Sublingual granules of the fast-acting activating composition, infusion granules of the intermediate-acting consolidation composition, and sustained-release pills of the long-acting nourishing composition were prepared separately. The three prepared compositions are packaged according to the dosage of one conditioning cycle; the dosage package of one conditioning cycle contains: 3 units of the fast-acting activating composition, 4 units of the medium-acting consolidation composition and at least 14 units of the long-acting nourishing composition.
10. The use of the three-stage targeted warming and kidney-tonifying composition according to any one of claims 1-9 in the preparation of a food-medicine supplement for improving male sub-health conditions.