Intrinsic antibacterial nylon 66 material for large trauma surgery suture and preparation method thereof

Abstract

This invention belongs to the field of polymer materials technology and discloses an intrinsically antibacterial nylon 66 material for large-scale surgical sutures and its preparation method. The material possesses excellent mechanical properties, a high melting point, and good wear resistance, while also exhibiting excellent antibacterial properties. Furthermore, the preparation method uses fewer raw materials, has a simple production process, and is suitable for large-scale production, making it well-suited for applications in the medical field.

Description

Technical Field

[0001] This invention belongs to the field of polymer materials technology, specifically relating to an intrinsic antibacterial nylon 66 material for use in large trauma surgery sutures and its preparation method. Background Technology

[0002] With the rapid development of the medical industry, the performance requirements for materials used in specific scenarios are becoming increasingly stringent, especially for sutures in major surgical procedures. These suture materials require high strength and toughness, as well as certain temperature and weather resistance. Nylon 66 is one of the most widely used synthetic resins and also one of the most wear-resistant, possessing excellent strength, toughness, good temperature resistance, and a certain degree of weather resistance, making it an ideal material for sutures in major surgical procedures. However, Nylon 66 is prone to contamination with pathogens during its production process, and direct application in the medical field could negatively impact patient health. Therefore, copolymerizing Nylon 66 with other antibacterial structures to impart intrinsic antibacterial properties is currently a key research focus.

[0003] Chinese invention patent CN202310149892.0 discloses "An intrinsically antibacterial nylon and its preparation method and application." This method utilizes copolymerization, dissolving raw materials A, B, C, and D in a specific molar ratio in the same solvent system (the solvent is any one or more combinations of diethyl ether, tetrahydrofuran, dimethyl sulfoxide, ethylene glycol dimethyl ether, anisole, m-nitrobenzene, p-chloroanisole, methyl isobutyl ketone, acetophenone, p-chloroacetophenone, o-nitrobenzene, sulfolane, dichloromethane, chloroform, 1,2-dichloroethane, chlorobenzene, α-chloronaphthalene, acetonitrile, propionitrile, benzene, toluene, cyanobenzene, nitrobenzene, nitrobenzene, ethyl acetate, and methyl benzoate). The structural formula of raw material A is... (R1 is a benzene ring, a C1-C10 straight-chain hydrocarbon group), raw material B is furan dicarboxaldehyde, and the structural formula of raw material C is... (R3 is a benzene ring, a C1-C10 straight-chain hydrocarbon group) or (R 3i (A C5 straight-chain hydrocarbon group), the structural formula of the raw material D is: (R4 is a furan ring, benzene ring, pyrazine ring, or a C1-C3 straight-chain hydrocarbon group; however, when R1 and R3 are the same, R4 is a benzene ring, pyrazine ring, or a C1-C3 straight-chain hydrocarbon group). The raw materials are then poured into a reaction vessel and stirred until homogeneous. The reaction is carried out at 50–70°C for 12–24 hours. After the reaction, the mixture is filtered from the reaction system to obtain the target intrinsic antibacterial nylon product. This method involves a variety of raw materials, requires the reaction to be carried out in an organic solvent system, resulting in high costs. The solvent also poses certain health risks. Furthermore, it cannot produce high-molecular-weight intrinsic antibacterial nylon polymer products, making industrial production difficult and hindering subsequent processing.

[0004] Chinese invention patent CN202310181452.3 discloses "An intrinsic antibacterial nylon and its preparation method and application". The intrinsic antibacterial nylon provided by this invention is prepared by homopolymerization. The intrinsic antibacterial nylon is prepared by polymerization, wherein R1 is a benzene ring or a C1-C10 straight-chain hydrocarbon group, and R2 is a furan ring, a benzene ring, a pyrazine ring, or a C1-C3 straight-chain hydrocarbon group. This nylon, after being uniformly mixed with additives or modifiers, is injection molded and exhibits long-lasting antibacterial properties. However, this method requires the addition of organic additives or modifiers, and the resulting intrinsic antibacterial nylon has a relatively low molecular weight, still posing some harm to the human body and making industrial production and subsequent processing difficult. Summary of the Invention

[0005] To overcome the shortcomings of existing technologies, this invention provides an intrinsic antibacterial nylon 66 material for large trauma surgery sutures and its preparation method. The patented raw materials are few in number and the process is simple; no organic solvents are required during preparation, making it safe and environmentally friendly; it can produce high molecular weight polymer products, facilitating subsequent processing; and it provides mechanical properties and melting point parameters, making its application scenarios more extensive.

[0006] The above-mentioned objective of this invention is achieved through the following technical solution: an intrinsically antibacterial nylon 66 material, comprising adipic acid, hexamethylenediamine, and a material with the structural formula […]. Diamines (where R represents benzene ring, naphthalene ring, or furan ring) are mixed with deionized water in a certain proportion and added to a reaction vessel. Through copolymerization, the intrinsic antibacterial structure and the rigid benzene ring structure are copolymerized into the nylon 66 macromolecule, thereby increasing the temperature resistance and antibacterial properties of the material while maintaining the excellent mechanical properties of nylon 66.

[0007] Furthermore, the adipic acid:hexamethylenediamine: structural formula is as follows: The mass ratio of diamines (where R represents a benzene ring, naphthalene ring, or furan ring) is (1.5-2.0):(1.0-1.5):(0.5-1.0); hexamethylenediamine and the structural formula is The total number of moles of diamines (where R represents benzene ring, naphthalene ring, or furan ring) added is the same as the number of moles of adipic acid added as the raw material.

[0008] Another object of the present invention is to protect the preparation method of the above-mentioned intrinsic antibacterial nylon 66 material, the steps of which include:

[0009] Step 1: Select adipic acid as raw material X, hexamethylenediamine as raw material Y, and a compound with the following structural formula: The diamine (R represents a benzene ring, naphthalene ring, or furan ring) was prepared using deionized water as a solvent. Raw materials X, Y, and Z were mixed with the solvent in a specific ratio. After mixing, a copolymerization salt formation reaction was carried out for 1-2 hours under an inert atmosphere, at normal pressure, with a stirring speed of 100-180 rpm and a temperature of 50-90℃. The pH of the resulting copolymer salt solution was measured. When the pH was within the range of 6.8-8.5, the salt formation reaction was considered complete, yielding the amide salt W with the structural formula [structural formula would be inserted here].

[0010] (R represents a benzene ring, naphthalene ring, or furan ring);

[0011] Step 2: Add the prepared amide salt solution to the reaction vessel, raise the temperature to 120-180℃, maintain the pressure inside the reaction vessel at 0.1-0.5MPa, and stir at 30-80rpm for 0.5-3 hours. Concentration is complete when the salt solution concentration reaches 70-90%.

[0012] Step 3: Increase the temperature to 180-240℃, increase the pressure to 1.5-1.9MPa, and stir at 30-80rpm for 1-4 hours;

[0013] Step 4: Increase the temperature to 240-270℃, increase the pressure to 1.7-2.0MPa, and stir at 30-80rpm for 1-3 hours;

[0014] Step 5: Release the pressure inside the reactor to atmospheric pressure, raise the temperature to 270-320℃, stir at 30-80 rpm, and depressurize for 0.6-2.5 hours;

[0015] Step Six: Vacuum for 0.6-2.5 hours, maintaining the temperature at 270-320℃. Finally, use nitrogen to equalize the pressure, discharge and cool the material, then pelletize to obtain the product. The product structure is as follows:

[0016]

[0017] Furthermore, in step one, the mass ratio of raw materials X:Y:Z is (1.5-2.0):(1.0-1.5):(0.5-1.0). The total number of moles of raw materials Y and Z added is the same as the number of moles of raw material adipic acid added.

[0018] Furthermore, in step one, the stirring speed is preferably 145-155 rpm, the temperature is preferably 70-85℃, the reaction time is preferably 0.6-1.5 h, and the pH of the copolysalt solution in step one is preferably 7.6-7.9.

[0019] Furthermore, in step two, the reaction temperature is preferably 140-155℃, the pressure inside the reaction vessel is preferably 0.2-0.4MPa, the stirring speed is preferably 45-55rpm, the concentration of the concentrated salt solution is preferably 75-85%, and the concentration time is preferably 1-2h.

[0020] Furthermore, in step three, the preferred reaction temperature is 190-210℃, the preferred reaction pressure is 1.7-1.8MPa, the preferred stirring speed is 45-55rpm, and the preferred reaction time is 2-3h.

[0021] Furthermore, in step four, the preferred reaction temperature is 250-260℃, the preferred reaction pressure is 1.7-1.8MPa, the preferred stirring speed is 45-55rpm, and the preferred reaction time is 1-1.5h.

[0022] Furthermore, in step five, the preferred reaction temperature is 270-300℃, the preferred pressure relief time is 0.6-1.5h, and the preferred stirring speed is 45-55rpm.

[0023] Furthermore, in step six, the vacuuming time is preferably 0.6-1.5 h, and the reaction temperature is preferably 270-300 °C.

[0024] Another object of the present invention is to protect the application of the above-mentioned intrinsic antibacterial nylon 66 material, specifically in the application of sutures for large trauma surgeries.

[0025] The beneficial effects of this invention compared to the prior art are:

[0026] This patented technology requires fewer types of raw materials and involves a simpler process; it eliminates the need for organic solvents during preparation, making it safe and environmentally friendly; it can produce high molecular weight polymer products, facilitating subsequent processing; and it provides mechanical properties and melting point parameters, enabling a wider range of applications.

[0027] The novel intrinsically antibacterial nylon 66 material obtained by this invention has a tensile strength of over 90 MPa, an elongation at break of over 100%, a melting point of over 270°C, and a friction and wear limit PV value greater than 2100 kg / cm². 2 The antibacterial activity against *Escherichia coli* and *Staphylococcus aureus* is above 98% in m / min. The novel intrinsically antibacterial nylon 66 material prepared according to the preferred conditions exhibits a tensile strength above 98 MPa, an elongation at break above 110%, a melting point above 290°C, and a friction and wear limit PV value greater than 2200 kg / cm².2 With a concentration of m / min, the antibacterial activity against Escherichia coli and Staphylococcus aureus is over 100%. Detailed Implementation

[0028] The present invention is described in detail below through specific embodiments, but this does not limit the scope of protection of the present invention. Unless otherwise specified, the experimental methods used in the present invention are all conventional methods, and the experimental equipment, materials, reagents, etc. used can all be obtained commercially.

[0029] The following raw material X is adipic acid, raw material Y is hexamethylenediamine, and raw material Z has the following structural formula: (R is a diamine of benzene ring, naphthalene ring, or furan ring).

[0030] Example 1

[0031] Weigh 1.5 mol of raw material X, 1 mol of raw material Y, 0.5 mol of raw material Z, and 1000 g of deionized water. Add the weighed raw materials to the reaction vessel and purge with nitrogen three times. Set the reaction temperature to 50℃ and the stirring speed to 155 rpm. After 1.5 h of reaction, take a sample to measure the pH. When the pH is between 7.6 and 7.9, the salt formation reaction is complete.

[0032] The reaction temperature was increased to 120℃, the pressure inside the vessel was increased to 0.2MPa, the stirring speed was set to 45rpm, and after 2 hours of concentration, the amount of water discharged was weighed. The concentration of the salt solution was calculated based on the amount of water discharged and concentrated to 80%. The concentration was then completed.

[0033] The reaction temperature was increased to 180℃ and the reaction pressure was increased to 1.75MPa. The reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve. The stirring speed was set to 45rpm and the reaction was carried out for 3 hours.

[0034] The reaction temperature was increased to 240℃, the reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve, the stirring speed was maintained at 45rpm, and the reaction was carried out for 1.5h.

[0035] The pressure in the reactor is slowly released to atmospheric pressure over a period of approximately 1.5 hours. During this process, the temperature inside the reactor will continue to rise. The temperature control is adjusted to maintain the temperature inside the reactor at 270°C. As the viscosity of the polymer inside the reactor increases, the stirring speed will gradually decrease. When the pressure is released to atmospheric pressure, the stirring speed will decrease to approximately 45 rpm.

[0036] Turn on the vacuum pump to make the pressure inside the reactor < -50KPa. During this process, the temperature inside the reactor will continue to rise. Adjust the temperature control to maintain the temperature inside the reactor at 270℃. After 1.5 hours, observe the stirring speed. When the stirring speed drops to about 30 rpm, stop the vacuuming and introduce nitrogen into the reactor to equalize the pressure. After standing for 0.5 hours, open the discharge valve. After the material is discharged and cooled, it is pelletized to obtain the product Nylon 1#.

[0037] Example 2

[0038] Weigh 1.5 mol of raw material X, 1 mol of raw material Y, 0.5 mol of raw material Z, and 1000 g of deionized water. Add the weighed raw materials to the reaction vessel and purge with nitrogen three times. Set the reaction temperature to 55℃ and the stirring speed to 155 rpm. After reacting for 1 hour, take a sample to measure the pH. When the pH is between 7.6 and 7.9, the salt formation reaction is complete.

[0039] The reaction temperature was increased to 130℃, the pressure inside the vessel was increased to 0.3MPa, the stirring speed was set to 45rpm, and after concentration for 1.5h, the amount of water discharged was weighed. The concentration of the salt solution was calculated based on the amount of water discharged and concentrated to 85%. The concentration was then completed.

[0040] The reaction temperature was increased to 190℃ and the reaction pressure was increased to 1.75MPa. The reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve. The stirring speed was set to 45rpm and the reaction was carried out for 2.5h.

[0041] The reaction temperature was increased to 245℃, the reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve, the stirring speed was maintained at 45rpm, and the reaction was carried out for 1 hour.

[0042] The pressure in the reactor is slowly released to atmospheric pressure over a period of approximately 1 hour. During this process, the temperature inside the reactor will continue to rise. The temperature control is adjusted to maintain the temperature inside the reactor at 270°C. As the viscosity of the polymer inside the reactor increases, the stirring speed will gradually decrease. When the pressure is released to atmospheric pressure, the stirring speed will decrease to approximately 45 rpm.

[0043] Turn on the vacuum pump to make the pressure inside the reactor < -50KPa. During this process, the temperature inside the reactor will continue to rise. Adjust the temperature control to maintain the temperature inside the reactor at 270℃. After 1 hour, observe the stirring speed. When the stirring speed drops to about 30rpm, stop the vacuuming and introduce nitrogen into the reactor to equalize the pressure. After standing for 0.5 hours, open the discharge valve. After the material is discharged and cooled, it is granulated to obtain the product Nylon 2#.

[0044] Example 3

[0045] Weigh 1.5 mol of raw material X, 1 mol of raw material Y, 0.5 mol of raw material Z, and 1000 g of deionized water. Add the weighed raw materials to the reaction vessel and purge with nitrogen three times. Set the reaction temperature to 60℃ and the stirring speed to 155 rpm. After 0.6 h of reaction, take a sample to measure the pH. When the pH is between 7.6 and 7.9, the salt formation reaction is complete.

[0046] The reaction temperature was increased to 140℃, the pressure inside the vessel was increased to 0.4MPa, the stirring speed was set to 45rpm, and after concentration for 1 hour, the amount of water discharged was weighed. The concentration of the salt solution was calculated based on the amount of water discharged and concentrated to 85%. The concentration was then completed.

[0047] The reaction temperature was increased to 200℃ and the reaction pressure was increased to 1.75MPa. The reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve. The stirring speed was set to 45rpm and the reaction was carried out for 2 hours.

[0048] The reaction temperature was raised to 250℃, the reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve, the stirring speed was maintained at 45rpm, and the reaction was carried out for 1 hour.

[0049] The pressure in the reactor is slowly released to atmospheric pressure over a period of approximately 0.6 hours. During this process, the temperature inside the reactor will continue to rise. The temperature control is adjusted to maintain the temperature at 270°C. As the viscosity of the polymer inside the reactor increases, the stirring speed will decrease. When the pressure is released to atmospheric pressure, the stirring speed will decrease to approximately 45 rpm.

[0050] Turn on the vacuum pump to make the pressure inside the reactor < -50KPa. During this process, the temperature inside the reactor will continue to rise. Adjust the temperature control to maintain the temperature inside the reactor at 270℃. After 0.6h, observe the stirring speed. When the stirring speed drops to about 30rpm, stop the vacuuming and introduce nitrogen into the reactor to equalize the pressure. After standing for 0.5h, open the discharge valve. After the material is discharged and cooled, it is granulated to obtain the product Nylon 3#.

[0051] Example 4

[0052] Weigh 1.5 mol of raw material X, 1 mol of raw material Y, 0.5 mol of raw material Z, and 1000 g of deionized water. Add the weighed raw materials to the reaction vessel and purge with nitrogen three times. Set the reaction temperature to 70℃ and the stirring speed to 155 rpm. After 1.5 h of reaction, take a sample to measure the pH. When the pH is between 7.6 and 7.9, the salt formation reaction is complete.

[0053] The reaction temperature was increased to 155℃, the pressure inside the vessel was increased to 0.2MPa, the stirring speed was set to 45rpm, and after 2 hours of concentration, the amount of water discharged was weighed. The concentration of the salt solution was calculated based on the amount of water discharged and concentrated to 83%. The concentration was then completed.

[0054] The reaction temperature was increased to 190℃ and the reaction pressure was increased to 1.75MPa. The reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve. The stirring speed was set to 45rpm and the reaction was carried out for 2 hours.

[0055] The reaction temperature was increased to 255℃, the reaction pressure was maintained at 1.75MPa by adjusting the exhaust valve, the stirring speed was maintained at 45rpm, and the reaction was carried out for 1 hour.

[0056] The pressure in the reactor is slowly released to atmospheric pressure over a period of approximately 0.6 hours. During this process, the temperature inside the reactor will continue to rise. The temperature control is adjusted to maintain the temperature at 290°C. As the viscosity of the polymer inside the reactor increases, the stirring speed will gradually decrease. When the pressure is released to atmospheric pressure, the stirring speed will decrease to approximately 45 rpm.

[0057] Turn on the vacuum pump to make the pressure inside the reactor < -50KPa. During this process, the temperature inside the reactor will continue to rise. Adjust the temperature control to maintain the temperature inside the reactor at 290℃. After 0.6h, observe the stirring speed. When the stirring speed drops to about 30rpm, stop the vacuuming and introduce nitrogen into the reactor to equalize the pressure. After standing for 0.5h, open the discharge valve. After the material is discharged and cooled, it is granulated to obtain the product Nylon 4#.

[0058] Comparative Example 1

[0059] Using malonyl hydrazide, furanyl dicarboxaldehyde, octanediamine, and terephthalaldehyde as raw materials, the raw material addition ratio was malonyl hydrazide: furanyl dicarboxaldehyde: octanediamine: terephthalaldehyde (molar ratio) of 1:1:9:9. The weighed raw materials were mixed and dissolved in the organic solvent dimethyl sulfoxide, and reacted at 70°C for 24 hours. After the reaction was completed, the reaction system was filtered to obtain the comparative product, nylon 5#, with the following structural formula:

[0060]

[0061] Comparative Example 2

[0062] Using adipic acid dihydrazide, furanyl dicarboxaldehyde, pentanediamine, and furanyl dicarboxaldehyde as raw materials, the raw material addition ratio was adipic acid dihydrazide: furanyl dicarboxaldehyde: pentanediamine: furanyl dicarboxaldehyde (molar ratio) of 1:1:1:1. The weighed raw materials were mixed and dissolved in the organic solvent chloroform, and reacted at 70°C for 24 hours. After the reaction was completed, the reaction system was filtered to obtain the comparative product, nylon 6#, with the following structural formula:

[0063]

[0064] Table 1 Performance testing standards for examples and comparative examples

[0065] Testing items Test Standards Tensile strength GB / T1040.2 Determination of tensile properties of plastics Elongation at break GB / T1040-79 Plastics Tensile Testing Method Friction and wear limit PV value ISO6601 Plastics Sliding Friction and Wear Melting point GB / T19466.3 Determination of melting and crystallization temperature and enthalpy Antibacterial GB / T31402 Test Method for Antibacterial Properties of Plastic Surfaces

[0066] Table 2 Performance test results of Examples 1-4 and Comparative Examples 1-2

[0067]

[0068] The present invention discloses an intrinsically antibacterial nylon 66 material for large trauma surgical sutures, which possesses excellent mechanical properties, a high melting point, and good wear resistance, while also exhibiting excellent antibacterial properties. Furthermore, the preparation method of this material uses fewer raw materials, has a simple production process, is suitable for large-scale production, and can be well applied in the medical field.

[0069] The embodiments described above are merely preferred embodiments of the present invention, and not all feasible embodiments of the present invention. Any obvious modifications made by those skilled in the art without departing from the principles and spirit of the present invention should be considered to be included within the scope of protection of the claims of the present invention.

Claims

1. An intrinsically antibacterial nylon 66 material, characterized in that, The components include adipic acid, hexamethylenediamine, and a compound with the following structural formula: The diamine, wherein R is a benzene ring, a naphthalene ring, or a furan ring.

2. The intrinsically antibacterial nylon 66 material according to claim 1, characterized in that, The adipic acid and hexamethylenediamine have the following structural formula: The mass ratio of the diamines is (1.5-2.0):(1.0-1.5):(0.5-1.0); hexamethylenediamine and the structural formula is The total number of moles of diamine added is the same as the number of moles of adipic acid added as the raw material.

3. A method for preparing an intrinsically antibacterial nylon 66 material, characterized in that the step... include: S1. Select adipic acid as raw material X, hexamethylenediamine as raw material Y, and a compound with the following structural formula: The diamine was obtained by using deionized water as a solvent. Raw materials X, Y, and Z were mixed with the solvent in a specific ratio. After mixing, a copolymerization salt formation reaction was carried out for 1-2 hours under an inert atmosphere, at normal pressure, with a stirring speed of 100-180 rpm and a temperature of 50-90℃. The pH of the resulting copolymer salt solution was measured. When the pH was within the range of 6.8-8.5, the salt formation reaction was considered complete, yielding the amide salt W with the structural formula [structure omitted]. Where R represents a benzene ring, a naphthalene ring, or a furan ring; S2. Add the prepared amide salt solution to the reaction vessel, raise the temperature to 120-180℃, maintain the pressure inside the reaction vessel at 0.1-0.5MPa, stir at 30-80rpm, concentrate for 0.5-3h, and stop the concentration when the salt solution concentration reaches 70-90%. S3. Increase the temperature to 180-240℃, increase the pressure to 1.5-1.9MPa, and stir at 30-80rpm for 1-4 hours; S4. Heat to 240-270℃, increase pressure to 1.7-2.0MPa, stir at 30-80rpm, and react for 1-3 hours; S5. Release the pressure inside the reactor to atmospheric pressure, raise the temperature to 270-320℃, stir at 30-80 rpm, and depressurize for 0.6-2.5 hours; S6. Vacuum for 0.6-2.5 hours, maintain temperature at 270-320℃, finally apply nitrogen pressure, discharge, cool, and pelletize to obtain the product. The product structure is as follows:

4. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S1, the mass ratio of raw materials X:Y:Z is (1.5-2.0):(1.0-1.5):(0.5-1.0). The total number of moles of raw materials Y and Z added is the same as the number of moles of raw material adipic acid added.

5. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S1, the stirring speed is 145-155 rpm, the temperature is 70-85℃, the reaction time is 0.6-1.5 h, and the pH of the copolysalt solution in step one is 7.6-7.

9.

6. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S2, the reaction temperature is 140-155℃, the pressure inside the reactor is 0.2-0.4MPa, the stirring speed is 45-55rpm, the concentration of the concentrated salt solution is 75-85%, and the concentration time is 1-2h.

7. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S3, the reaction temperature is 190-210℃, the reaction pressure is 1.7-1.8MPa, the stirring speed is 45-55rpm, and the reaction time is 2-3h.

8. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S4, the reaction temperature is 250-260℃, the reaction pressure is 1.7-1.8MPa, the stirring speed is 45-55rpm, and the reaction time is 1-1.5h.

9. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S5, the reaction temperature is 270-300℃, the depressurization time is 0.6-1.5h, and the stirring speed is 45-55rpm.

10. The method for preparing the intrinsic antibacterial nylon 66 material according to claim 3, characterized in that, In step S6, the vacuuming time is 0.6-1.5 hours and the reaction temperature is 270-300°C.

11. The application of the intrinsically antibacterial nylon 66 material as described in claim 1, characterized in that, Specifically used in sutures for major trauma surgeries.

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