Glucose, cortisol, sodium ion and pH detection sensors and their preparation methods

By designing sensors for detecting glucose, cortisol, sodium ions, and pH, and utilizing biomimetic microfluidic units and sweat-wicking fabric layers to achieve unidirectional moisture-wicking transmission of sweat, the problem of real-time multi-parameter detection in existing technologies is solved, improving the accuracy and efficiency of detection, and making it suitable for wearable applications.

CN122296876APending Publication Date: 2026-06-30HUAZHONG UNIV OF SCI & TECH
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Patent Information

Application Number
CN202610761190.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-29
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing technologies struggle to achieve real-time multi-parameter detection of glucose, cortisol, sodium ions, and pH in sweat, and traditional detection devices are bulky and complex to operate, making them unsuitable for wearable applications.

Method used

A sensor for detecting glucose, cortisol, sodium ions, and pH was designed, comprising a base layer, a detection module, and a biomimetic microfluidic unit. Combined with a biomimetic sweat-guiding fabric layer, it enables unidirectional moisture-wicking transport of sweat and performs synchronous detection through a multi-parameter detection module.

Benefits of technology

It enables real-time synchronous detection of multiple parameters in sweat, improving detection accuracy and efficiency, making it suitable for wearable applications, and providing good comfort and resistance to sweat interference.

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Abstract

This invention discloses a sensor for detecting glucose, cortisol, sodium ions, and pH, and its preparation method, belonging to the field of sensor technology. It includes a substrate layer, a detection module disposed above the substrate layer, and the detection module comprising a glucose detection module, a cortisol detection module, a sodium ion detection module, and a pH detection module; as well as a biomimetic microfluidic unit and a biomimetic sweat-guiding fabric layer. This invention achieves simultaneous real-time detection of multiple parameters in sweat, including glucose, cortisol, sodium ion concentrations, and pH, through the glucose, cortisol, sodium ion, and pH detection modules. Simultaneously, the biomimetic sweat-guiding fabric layer constructs a wettability gradient between the hydrophilic and hydrophobic sides, enabling unidirectional moisture-guiding transport of sweat from the skin side to the detection side. This effectively improves sweat collection efficiency, inhibits sweat backflow, and enhances the accuracy of glucose, cortisol, sodium ion concentration, and pH detection in sweat.
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