A method for improving quality and yield of target herbs and strengthening anticancer activity based on meteorite powder and meteorite water
By preparing and applying nano or micron-sized meteorite powder and meteorite water, the problems of insufficient anti-cancer activity and trace element imbalance in the existing cultivation of Chinese herbal medicines have been solved, thereby improving the yield and quality of herbs. Moreover, there is no chemical pollution, making it suitable for large-scale application.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Filing Date
- 2026-03-03
- Publication Date
- 2026-07-14
AI Technical Summary
Existing cultivation techniques for anti-cancer Chinese herbal medicines have drawbacks such as limited increase in anti-cancer active ingredients, imbalance in trace element supply, easy soil compaction or excessive heavy metals, and complex and costly operation. Meteorite-related materials have not been systematically integrated for targeted quality improvement, yield increase, and enhancement of anti-cancer activity of target herbs.
Nano or micron-sized meteorite powder is prepared from natural stony meteorites that are non-radioactive and meet heavy metal standards. Combined with meteorite water, it is used to promote the growth of herb seeds and plants through seed dressing, irrigation, and foliar spraying, and to provide a balanced supply of macroelements such as Fe, Mg, Si, and Ca, as well as microelements such as Se, Zn, Mo, Co, and Ni.
It significantly enhances the anti-cancer active ingredients, increases the yield and quality of medicinal materials, balances the distribution of trace elements, improves soil structure, is easy to operate and environmentally friendly, and is suitable for large-scale promotion.
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Figure CN122375423A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the interdisciplinary field of traditional Chinese medicine cultivation and functional agriculture, specifically a method for improving the quality and yield of target herbs and enhancing their anti-cancer activity based on meteorite powder and meteorite water. Background Technology
[0002] Anti-cancer Chinese herbal medicines are core raw materials for traditional Chinese medicine and modern anti-cancer drug research and development. Their active ingredients, such as paclitaxel, polysaccharides, and alkaloids, are widely used in clinical anti-cancer treatment and health preservation. Current cultivation techniques for anti-cancer Chinese herbal medicines mainly aim to increase the yield and activity of these active ingredients by applying chemical fertilizers, spraying plant growth regulators, and optimizing environmental parameters. However, these methods have drawbacks, including limited increases in the amount of active anti-cancer ingredients, imbalances in micronutrient supply, potential for soil compaction or heavy metal contamination, and complex and costly operations.
[0003] Meteorites, as natural cosmic mineral resources, are rich in macroelements such as Fe, Mg, Si, and Ca, as well as functional trace elements such as Se, Zn, Mo, Co, and Ni. Their powder and extracts (meteorite water) possess unique physicochemical properties that can promote the absorption and transformation of nutrients by plants. Currently, meteorite-related materials have not been systematically integrated for targeted quality improvement, yield enhancement, and anti-cancer activity enhancement of medicinal herbs, failing to address the core pain points of existing cultivation techniques. Summary of the Invention
[0004] To address the shortcomings of existing technologies, this invention provides a method for improving the quality and yield of targeted medicinal herbs and enhancing their anti-cancer activity based on meteorite powder and meteorite water. This method solves the problem that existing meteorite-related materials have not yet been systematically integrated into the targeted improvement, yield enhancement, and anti-cancer activity enhancement of anti-cancer Chinese herbal medicines.
[0005] To achieve the above objectives, the present invention provides the following technical solution: a method for improving the quality and yield of target herbal medicines and enhancing their anticancer activity based on meteorite powder and meteorite water, comprising the following steps:
[0006] S1. Preparation of meteorite powder: Select natural stony meteorites that are free of radioactivity and meet the standards for heavy metals, and clean, dry, crush, and ball mill them to the nanoscale (10-100nm) or microscale (1-10μm) size. Then, pass them through a 100-200 mesh sieve to obtain meteorite powder.
[0007] S2. Preparation of meteorite water: Add the meteorite powder obtained in step S1 to water at a ratio of 50-100g / L, and obtain meteorite water by ultrasonic treatment, magnetic stirring, standing, and filtration.
[0008] S3. Meteorite powder seed dressing: After disinfecting the target herb seeds, add 20-30% of the seed weight of the meteorite powder obtained in step S1, mix evenly to coat the seed surface with meteorite powder, dry and then sow.
[0009] S4. Meteorite water irrigation: After the target herb is sown or transplanted and has recovered from transplanting, irrigate with the meteorite water obtained in step S2 every 7-15 days. Each irrigation should be 200-500 mL / plant or 1500-3000 mL / m². Irrigate a total of 3-8 times from the seedling stage to the harvest stage.
[0010] S5. Meteorite water foliar spraying: During the vigorous growth period of the target herb, spray the foliage with the meteorite water obtained in step S2 every 5-10 days, with a spraying volume of 100-300mL / m² each time.
[0011] In some embodiments, the preparation conditions of the meteorite powder in step S1 are as follows: drying temperature 60-80℃, time 8-12h; ball milling using a planetary ball mill, ball-to-material ratio 8:1, rotation speed 300-500r / min, time 2-4h.
[0012] In some embodiments, the main element content (mass fraction) of the meteorite powder in step S1 is: Fe 15-30%, Mg 5-15%, Si 10-25%, Ca 2-8%, and the trace element content is: Se 0.01-0.1%, Zn 0.1-0.5%, Mo 0.001-0.01%, Co 0.005-0.05%, Ni 0.05-0.2%.
[0013] In some embodiments, the ultrasonic treatment in step S2 is performed with a power of 200-500W for 30-60 minutes; the magnetic stirring speed is 1000-2000 r / min for 1-2 hours; the settling time is 24-48 hours; and a 0.22μm organic filter membrane is used for filtration.
[0014] In some embodiments, the meteorite water in step S2 is further enriched with 0.05-0.2% (v / v) of surfactant or 0.1-0.5% (w / v) of humic acid.
[0015] In some embodiments, the seed disinfection in step S3 involves soaking the seeds in a 5% sodium hypochlorite solution for 10-15 minutes, followed by rinsing with deionized water until neutral.
[0016] In some embodiments, the key periods for meteorite water irrigation in step S4 are the seedling stage, flowering stage, fruiting stage, or 30 days before the harvest of medicinal materials, and the irrigation frequency during the key periods is once every 7 days.
[0017] In some embodiments, the meteorite water used for foliar spraying in step S5 contains 0.01-0.05% (w / v) potassium dihydrogen phosphate or 0.05-0.1% (w / v) amino acid foliar fertilizer; spraying should be avoided during high temperatures (>35°C) and rainy days.
[0018] A compound cultivation preparation comprising meteorite powder and meteorite water;
[0019] The meteorite powder has a particle size of 10nm-10μm and mainly contains elements such as Fe, Mg, Si, and Ca.
[0020] The meteorite water is a suspension or solution formed by dispersing the meteorite powder in water.
[0021] This invention provides a method for improving the quality and yield of target herbal medicines and enhancing their anticancer activity based on meteorite powder and meteorite water, which has the following beneficial effects:
[0022] Significantly increased anti-cancer active ingredients: Trace elements in meteorites activate the activity of key enzymes in plants, promoting the biosynthesis of anti-cancer active ingredients, resulting in higher content compared to conventional cultivation.
[0023] Significantly increased yield per unit area: Balanced mineral nutrition promotes root development and photosynthesis.
[0024] Balanced enrichment of trace elements: The content of macroelements and anti-cancer functional trace elements is significantly increased, and the elements are evenly distributed.
[0025] The quality of Chinese herbal medicines has been comprehensively optimized: there are no chemical residues, the resistance to adverse conditions is enhanced, the rate of deformed plants is reduced, the appearance and internal quality of the medicinal materials are improved simultaneously, and the shelf life is extended.
[0026] Green, environmentally friendly and sustainable: Natural mineral materials are free of chemical pollution, and long-term use can improve soil structure and achieve ecological and sustainable cultivation.
[0027] Easy to operate and cost controllable: The technical process is simple, no complicated equipment is required, it is compatible with a variety of cultivation modes, and it is easy to promote on a large scale. Attached Figure Description
[0028] Figure 1 This is a flowchart of the present invention. Detailed Implementation
[0029] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0030] Example 1
[0031] Please see Figure 1 This invention provides a technical solution: a method for improving the quality and yield of target herbal medicines and enhancing their anti-cancer activity based on meteorite powder and meteorite water, comprising the following steps:
[0032] S1. Preparation of meteorite powder: Select natural stony meteorites that are free of radioactivity and meet the standards for heavy metals, and clean, dry, crush, and ball mill them to the nanoscale (10-100nm) or microscale (1-10μm) size. Then, pass them through a 100-200 mesh sieve to obtain meteorite powder.
[0033] S2. Preparation of meteorite water: Add the meteorite powder obtained in step S1 to water at a ratio of 50-100g / L, and obtain meteorite water by ultrasonic treatment, magnetic stirring, standing, and filtration.
[0034] S3. Meteorite powder seed dressing: After disinfecting the target herb seeds, add 20-30% of the seed weight of the meteorite powder obtained in step S1, mix evenly to coat the seed surface with meteorite powder, dry and then sow.
[0035] S4. Meteorite water irrigation: After the target herb is sown or transplanted and has recovered from transplanting, irrigate with the meteorite water obtained in step S2 every 7-15 days. Each irrigation should be 200-500 mL / plant or 1500-3000 mL / m². Irrigate a total of 3-8 times from the seedling stage to the harvest stage.
[0036] S5. Meteorite water foliar spraying: During the vigorous growth period of the target herb, spray the foliage with the meteorite water obtained in step S2 every 5-10 days, with a spraying volume of 100-300mL / m² each time.
[0037] Among them, natural meteorites that are non-radioactive (meeting the basic standards for ionizing radiation protection and radiation source safety in GB 18871-2002) and free of excessive heavy metals (meeting the requirements for raw materials of traditional Chinese medicine in GB 2762-2022 National Food Safety Standard for Limits of Contaminants in Food) were selected.
[0038] In this embodiment, the preparation conditions of the meteorite powder in step S1 are as follows: drying temperature 60-80℃, time 8-12h; ball milling is carried out using a planetary ball mill with a ball-to-material ratio of 8:1, rotation speed 300-500r / min, and time 2-4h.
[0039] The stony meteorite is rinsed with deionized water 3-5 times to remove surface impurities. It is then dried in an oven at 60-80℃ for 8-12 hours until the moisture content is less than 5%. The meteorite is first crushed into particles with a diameter ≤1cm, and then fed into a planetary ball mill with agate balls as the grinding medium. The ball-to-material ratio is 8:1, the grinding speed is 300-500r / min, and the grinding time is 2-4 hours to obtain nano-sized (10-100nm) or micro-sized (1-10μm) powder.
[0040] In this embodiment, the main element content (mass fraction) of the meteorite powder in step S1 is: Fe 15-30%, Mg 5-15%, Si 10-25%, Ca 2-8%, and the trace element content is: Se 0.01-0.1%, Zn 0.1-0.5%, Mo 0.001-0.01%, Co 0.005-0.05%, Ni 0.05-0.2%.
[0041] In this embodiment, the ultrasonic treatment power in step S2 is 200-500W, the time is 30-60min; the magnetic stirring speed is 1000-2000r / min, the time is 1-2h; the standing time is 24-48h; and the filtration uses a 0.22μm organic filter membrane.
[0042] The ground powder is passed through a 100-200 mesh standard sieve, and the sieve-underfill material is collected to obtain meteorite powder. The above meteorite powder is slowly added to deionized water or natural water that meets the GB 5084-2021 "Standards for Irrigation Water Quality" at a ratio of 50-100 g / L, while stirring until it is evenly dispersed. Then, it is ultrasonically treated for 30-60 minutes with a power of 200-500W and a frequency of 40kHz to promote the dissolution of elements. Then, it is stirred with a magnetic stirrer at a speed of 1000-2000 r / min for 1-2 hours to ensure that the elements are fully dissolved. After standing and filtering, it is left to stand in a cool place for 24-48 hours. The supernatant is then filtered through a 0.22μm organic filter membrane to obtain pure meteorite water.
[0043] In this embodiment, the meteorite water in step S2 is further provided with 0.05-0.2% (v / v) of surfactant or 0.1-0.5% (w / v) of humic acid.
[0044] Adding 0.05-0.2% (v / v) of surfactant (such as Tween-80) or 0.1-0.5% (w / v) of humic acid can improve absorption efficiency.
[0045] In this embodiment, the seed disinfection in step S3 is performed by soaking the seeds in a 5% sodium hypochlorite solution for 10-15 minutes, and then rinsing them with deionized water until neutral.
[0046] Select plump, disease-free target herb seeds, such as ginseng, Ganoderma lucidum, and Astragalus membranaceus. Soak them in a 5% sodium hypochlorite solution for 10-15 minutes for disinfection, rinse with deionized water until neutral, and air dry the surface moisture.
[0047] In this embodiment, the key periods for the meteorite water irrigation in step S4 are the seedling stage, flowering stage, fruiting stage, or 30 days before the harvest of medicinal materials, and the irrigation frequency during the key periods is once every 7 days.
[0048] Weigh out 20-30% of the seed weight of meteorite powder, sprinkle it evenly on the seed surface, and stir quickly for 5-10 minutes until it is evenly coated. You can spray a small amount of deionized water to enhance the coating effect. After drying the seeds in a ventilated and shady place (avoid direct sunlight), you can sow or raise seedlings. The timing of irrigation is to start the first irrigation 7-10 days after sowing or transplanting and allow the seedlings to recover. Irrigate once every 7-15 days, and irrigate a total of 3-8 times from the seedling stage to the harvest stage. The seedling stage, flowering stage, and fruiting stage (or 30 days before harvest) are the key periods. The frequency is adjusted to once every 7 days. The irrigation amount is 200-500 mL / plant (potted plants) or 1500-3000 mL / m² (field) each time. Ensure that the soil moisture reaches 60-80% of the field water holding capacity. The irrigation method can be drip irrigation or furrow irrigation. Avoid flood irrigation.
[0049] In this embodiment, the meteorite water sprayed on the leaves in step S5 contains 0.01-0.05% (w / v) potassium dihydrogen phosphate or 0.05-0.1% (w / v) amino acid foliar fertilizer; spraying should be avoided during high temperatures (>35℃) and rainy days.
[0050] Spraying should begin during the vigorous growth period (from seedling stage to flowering stage), with a focus on spraying during the fruiting body formation stage or the rapid expansion stage of the medicinal material. Spraying frequency should be once every 5-10 days, for a total of 3-6 sprays. The spraying amount is 100-300mL / m², ideally wetting both sides of the leaves without dripping water. Avoid spraying during high temperatures (>35℃) or rainy days. If it rains within 4 hours after spraying, re-spraying is necessary.
[0051] A compound cultivation preparation comprising meteorite powder and meteorite water.
[0052] The meteorite powder has a particle size of 10nm-10μm and mainly contains elements such as Fe, Mg, Si, and Ca.
[0053] The meteorite water is a suspension or solution formed by dispersing the meteorite powder in water.
[0054] Example 2
[0055] Please see Figure 1 This invention provides a technical solution: a method for improving the quality and yield of target herbal medicines and enhancing their anti-cancer activity based on meteorite powder and meteorite water, comprising the following steps:
[0056] S1. Preparation of meteorite powder: Select non-radioactive natural stony meteorites that meet the heavy metal standards, clean them, dry them at 70℃ for 10 hours, crush them into particles smaller than 1 cm, grind them in a planetary ball mill for 3 hours (speed 400 r / min, ball-to-material ratio 8:1), and pass them through a 150-mesh sieve to obtain nano- / micron-sized meteorite powder; after testing, the elemental content meets the standards of Fe 15-30%, Mg 5-15%, Si 10-25%, Ca 2-8%, and trace element content.
[0057] S2. Preparation of meteorite water: Take 80g of the above meteorite powder, add 1L of deionized water, sonicate (400W, 45min), stir magnetically (1500r / min, 1.5h), let stand for 36h, take the supernatant and filter it through a 0.22μm filter membrane, add 0.1% Tween-80 and 0.3% humic acid to obtain meteorite water.
[0058] S3. Meteorite powder seed dressing: Disinfect the target herb seeds with 5% sodium hypochlorite solution for 12 minutes, rinse with deionized water until neutral, dry, add meteorite powder at 25% of the seed weight, stir for 8 minutes until evenly coated, ventilate and dry before sowing.
[0059] S4. Meteorite water irrigation: Start watering with meteorite water after sowing or after transplanting and seedling establishment. The amount of watering each time is adjusted according to the cultivation mode, once every 10 days. During the critical period (seedling period and flowering period), adjust to once every 7 days, for a total of 6 irrigations.
[0060] S5. Meteorite water foliar spraying: Start spraying meteorite water after the seedling stage, 150mL / m² each time, once every 7 days, add 0.03% potassium dihydrogen phosphate, spray a total of 5 times, and stop 30 days before harvest.
[0061] The rest is the same as in Example 1.
[0062] The method described in this application significantly enhances the anti-cancer active ingredients in medicinal herbs. Trace elements in meteorites activate the activity of key enzymes in plants, promoting the biosynthesis of anti-cancer active ingredients. Unit yield is significantly increased, balanced mineral nutrition promotes root development and photosynthesis, and trace elements are evenly enriched. The quality of medicinal herbs is comprehensively optimized, with no chemical residues, enhanced stress resistance, reduced rate of deformed plants, and simultaneous improvement in both appearance and internal quality, extending shelf life. It is green, environmentally friendly, and sustainable, with natural mineral materials free of chemical pollution. Long-term use can improve soil structure, achieving ecological and sustainable cultivation. The operation is simple, cost is controllable, the technical process is simple, no complex equipment is required, it is adaptable to various cultivation models, and it is easy to scale up.
[0063] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, the phrase "comprising an element defined as..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.
[0064] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A method for improving the quality, increasing the yield, and enhancing the anticancer activity of target medicinal herbs based on meteorite powder and meteorite water, characterized in that, Includes the following steps: S1. Preparation of meteorite powder: Select natural stony meteorites that are non-radioactive and meet the heavy metal standards, clean, dry, crush, and ball mill them to nanoscale or microscale, and pass them through a sieve with a preset mesh size to obtain meteorite powder; S2. Preparation of meteorite water: The meteorite powder obtained in step S1 is added to water in a preset ratio, and then subjected to ultrasonic treatment, magnetic stirring, standing, and filtration to obtain meteorite water. S3. Meteorite powder seed coating: After disinfecting the target herb seeds, add the meteorite powder obtained in step S1 according to the first preset weight of the seeds, mix evenly to coat the seed surface with meteorite powder, dry and then sow. S4. Meteorite water irrigation: After the target herb is sown or transplanted and has recovered from transplanting, irrigate it with the meteorite water obtained in step S2 once every first preset time. S5. Meteorite water foliar spraying: During the vigorous growth period of the target herb, spray the meteorite water obtained in step S2 onto the leaf surface once every first preset time.
2. The method according to claim 1, characterized in that, The preparation conditions for the meteorite powder in step S1 are: appropriate drying temperature and appropriate time; the ball milling uses a planetary ball mill with appropriate ball-to-material ratio, appropriate rotation speed, and appropriate time.
3. The method according to claim 1, characterized in that, The main elemental contents of the meteorite powder mentioned in step S1 are: Fe: 15%-30%, Mg 5%-15%, Si 10%-25%, Ca 2%-8%, and the trace element contents are: Se 0.01%-0.1%, Zn 0.1%-0.5%, Mo 0.001%-0.01%, Co 0.005%-0.05%, Ni 0.05%-0.2%.
4. The method according to claim 1, characterized in that, In step S2, the appropriate ultrasonic treatment power and time are rotated; the appropriate magnetic stirring speed and time are rotated; an appropriate settling time is selected for settling; and an organic filter membrane is used for filtration.
5. The method according to claim 1, characterized in that, The meteorite water described in step S2 also contains 0.05-0.2% (v / v) of surfactant or 0.1-0.5% (w / v) of humic acid.
6. The method according to claim 1, characterized in that, In step S3, the seeds are disinfected by soaking them in a 5% sodium hypochlorite solution at first preset intervals, and then rinsed with deionized water until neutral.
7. The method according to claim 1, characterized in that, The key periods for meteorite water irrigation in step S4 are the seedling stage, flowering stage, fruiting stage, or a preset number of days before the harvest of medicinal materials, and the irrigation frequency during the key periods is once every preset number of days.
8. The method according to claim 1, characterized in that, The meteorite water used for foliar spraying in step S5 contains 0.01-0.05% (w / v) potassium dihydrogen phosphate or 0.05-0.1% (w / v) amino acid foliar fertilizer; spraying should be avoided during high temperatures (>35℃) and rainy days.
9. A compound cultivation preparation, characterized in that, Including meteorite powder and meteorite water; The meteorite powder has a particle size of 10nm-10μm and mainly contains elements such as Fe, Mg, Si, and Ca. The meteorite water is a suspension or solution formed by dispersing the meteorite powder in water.