Filtering device and method for manufacturing thereof
The filter membrane and chip module prepared by photolithography lift-off process solve the problems of low CTC enrichment efficiency and severe cell damage in the existing technology, and realize high-purity and high-efficiency CTC capture, which is suitable for biomedical detection.
Patent Information
- Application Number
- CN202610555071.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-04-24
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies struggle to efficiently and effectively enrich circulating tumor cells (CTCs) from blood. This is because CTCs are present in extremely low concentrations and are mixed with a large number of red and white blood cells, resulting in low filtration efficiency and severe cell damage.
The filter membrane is prepared using a photolithography lift-off process to ensure that the size, shape, and array distribution of the filter pores are precisely controlled at the micron or even nanometer level. Combined with the chip module and one-way valve, it enables efficient capture of CTCs and effective interception of red blood cells and white blood cells.
It significantly improves the capture purity and capture rate of CTCs, reduces the risk of filter membrane clogging, maintains cell viability and filtration efficiency, and is suitable for high-throughput blood sample processing.
Smart Images
Figure CN122399567A_ABST