A method for correcting for concentration effect induced isotope ratio bias
By establishing a linear relationship model between concentration ratio and isotope ratio, the problem of isotope ratio deviation caused by concentration effect is solved, and high-precision isotope ratio correction is achieved. This model is applicable to various isotope systems, especially for accurate analysis of low-content samples.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- INSTITUTE OF GEOLOGY AND GEOPHYSICS CHINESE ACADEMY OF SCIENCES
- Filing Date
- 2026-05-20
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies are unable to effectively correct isotope ratio deviations caused by concentration effects, especially in low-content samples where multiple concentration matchings cannot be performed, leading to inaccurate analytical results and limiting the widespread application of isotope analysis techniques.
By establishing a linear relationship model between concentration ratio and isotope ratio, the concentration ratio of sample to standard solution is measured using a mass spectrometer. The linear relationship equation is obtained by fitting the equation using the least squares method. The corrected isotope ratio is then calculated, and the corrected isotope composition data is output.
It achieves high-precision isotope ratio correction under large concentration gradients, ensuring the accuracy and scientific rigor of low-content sample analysis, filling the technological gap in low-content sample research, and is applicable to various isotope systems.
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