Subpackaging protection box for medical isotopes and medicines thereof

By designing the multi-functional partitioning and automated control of the packaged protective box, the operational needs of medical isotope drug partitioning in different cleanliness environments are solved, and safe and efficient multi-step automated partitioning is achieved to meet GMP requirements.

CN223188907UActive Publication Date: 2025-08-05YANTAI DONGCHENG HEJU PHARMACEUTICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422495905.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-16
Publication Date
2025-08-05
Estimated Expiration
2034-10-16

AI Technical Summary

Technical Problem

The existing packing boxes cannot meet the multi-step operation requirements of medical isotopes and their drugs in different cleanliness environments, and the degree of manual participation is high, making it impossible to achieve automation and insufficient safety.

Method used

A separate protective box is designed, including the material front room, the main room and the rear room of the packaging, with a buffer room and a clean ventilation, sterilization and disinfection system, equipped with automatic packaging of lead cans and solid waste collection functions, and automatic control is achieved through the PLC system to meet the GMP requirements.

Benefits of technology

Environmental control at different cleanliness levels is realized, radiation damage to operators is reduced, operation convenience and safety is improved, and multiple batches are supported to continuously disassemble and use efficiency is improved.

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Abstract

The utility model provides a sub-packaging protection box for medical isotopes and drugs thereof, which comprises a material front chamber, a sub-packaging main chamber and a packaging rear chamber, the packaging rear chamber is divided into an upper layer space and a lower layer space, the lower layer space comprises a lead tank automatic packaging cabin and a radioactive solid waste temporary storage cabin, a buffer chamber I is arranged between the material front chamber and the sub-packaging main chamber, and a buffer chamber II is arranged between the material front chamber and the sub-packaging main chamber. And a buffer chamber II is arranged between the sub-packaging main chamber and the upper-layer space of the packaging rear chamber. According to the split charging protection box provided by the utility model, each functional zone can keep a reasonable differential pressure gradient, and the split charging protection box has the functions of clean ventilation, sterilization and disinfection, on-line monitoring and the like, and meets the requirements of relevant laws and regulations such as GMP (Good Manufacturing Practice) in China on clean environment, on-line monitoring, data auditing and tracking and the like in the production process. And meanwhile, the automatic lead tank packaging and solid waste collecting and storing functions are achieved, operation convenience and safety are improved, and radiation damage to operators is reduced to the minimum.
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Description

Technical Field

[0001] The utility model belongs to the technical field of radioactive medicine, in particular to a packaging protection box for medical isotopes and medicines thereof. Background Art

[0002] Existing packaging boxes can only meet the requirements of a single cleanliness level. However, the packaging of medical isotopes and their drugs involves multiple links, such as material preparation, liquid medicine packaging, and packaging. These operations require completion in different cleanliness environments. Therefore, existing protective boxes cannot meet such requirements.

[0003] In addition, the packaging of medical isotopes and their drugs is usually only automated through a packaging instrument in the step of liquid medicine packaging. Other steps still need to be completed manually by technicians, such as product packaging and solid waste disposal, and the human participation is relatively high. Utility Model Content

[0004] In order to solve the above-mentioned technical problems, the present invention provides a packaging and protection box for medical isotopes and their medicines. The functional areas of the packaging and protection box provided by the present invention can maintain a reasonable pressure gradient. Through functions such as clean ventilation, sterilization and disinfection, and online monitoring, it meets the requirements of relevant regulations such as China's GMP for clean environment, online monitoring, and data audit tracking during the production process. At the same time, it also has the functions of automatic packaging of lead cans and solid waste collection and storage, which improves the convenience and safety of operation and minimizes the radiation damage to operators. In addition, it can also be equipped with an automatic packaging instrument to realize multiple batches of continuous packaging of medical isotopes and their medicines, thereby improving the utilization efficiency of the packaging and protection box.

[0005] To achieve the above objectives, the present invention provides the following technical solutions:

[0006] A packaging and protective box for medical isotopes and medicines thereof comprises a material front chamber, a packaging main chamber and a packaging rear chamber; wherein the packaging rear chamber is divided into an upper space and a lower space, the upper space is provided with a material discharge port and a solid waste port; the lower space comprises an automatic packaging compartment for lead cans below the material discharge port, and a temporary storage compartment for radioactive solid waste below the solid waste port; a buffer chamber 1 is provided between the material front chamber and the packaging main chamber, and a buffer chamber 2 is provided between the packaging main chamber and the upper space of the packaging rear chamber; the material front chamber, the packaging main chamber and the packaging rear chamber are installed in a lead shielding box with protective function.

[0007] Furthermore, a front left door is provided between the buffer chamber 1 and the material front chamber, a front right door is provided between the buffer chamber 1 and the main packaging chamber, a rear right door is provided between the buffer chamber 2 and the main packaging chamber, and a rear left door is provided between the buffer chamber 2 and the upper space of the packaging rear chamber; a track is provided inside the buffer chamber 1, and a material tray sliding along the track is installed on the track.

[0008] Furthermore, the front left door, front right door, rear left door and rear right door are tempered glass doors or lead shielding doors, and can play a sealing role.

[0009] Furthermore, a sunken activity well is installed in the main packaging chamber, and the connection between the two is sealed to ensure the air tightness of the main packaging chamber.

[0010] Specifically, an automatic lifting mechanism is provided in the activity well, and the vial containing the drug solution can be sunk to the bottom of the activity well through the automatic lifting mechanism to complete the activity detection.

[0011] Furthermore, an opening and closing mechanism and a channel are provided at the bottom of the discharge port, and the channel is connected to the automatic packaging cabin of the lead cans; the opening and closing mechanism also has a sealing function to ensure the airtightness of the upper space of the packaging chamber.

[0012] Furthermore, there may be multiple discharge ports, each of which is provided with a corresponding number of channels. The inner diameters of the discharge ports and the corresponding channels are matched, and the discharge ports can be suitable for the transmission of vials of different specifications and volumes.

[0013] Furthermore, the automatic packaging cabin for lead cans includes a hatch 1, a translation mechanism 1, a lifting mechanism 1 and a lifting mechanism 2; the translation mechanism 1 includes a limiting slide 1, a track 1 and a drive assembly 1; the lifting mechanism 1 includes a plug-in 1 and a drive assembly 2, the plug-in 1 has a bayonet adapted to the lead can cover, which can act on the bottom of the lead can cover and move up and down to separate the lead can cover and the lead can body; the lifting mechanism 2 includes a U-shaped tray, multiple auxiliary slides and a drive assembly 3, the U-shaped tray is parallel to the translation mechanism 1, and is open at one end facing the hatch 1, the auxiliary slides are fixed inside the automatic packaging cabin for lead cans, and pass through both ends of the opening direction of the U-shaped tray; the outer ring of the limiting slide 1 has an annular groove that can engage the U-shaped tray.

[0014] Furthermore, the driving component 1 is installed at the bottom of the limiting slide 1, and can drive the limiting slide 1 to move on the track 1; the plug-in 1 of the lifting mechanism 1 is fixed at the lower end of the driving component 2, and moves up and down under the action of the driving component 2; the driving component 3 of the lifting mechanism 2 can drive the U-shaped pallet to move up and down.

[0015] Specifically, the driving assembly 1, driving assembly 2 and driving assembly 3 are selected from pneumatic cylinders or electric cylinders. The auxiliary sliding rods are symmetrically arranged. Preferably, there can be two auxiliary sliding rods, which are respectively installed at both ends of the opening of the U-shaped tray.

[0016] More specifically, when the lead can is placed on the limiting slide 1 and the hatch 1 is closed, the plug-in 1 is located in the gap between the lead can lid and the lead can body. The lifting mechanism 1 drives the plug-in 1 to lift the lead can lid, thereby realizing the separation operation of the lead can lid and the lead can body. The limiting slide 1 is driven by a pneumatic cylinder or an electric cylinder to move the lead can body on the track 1. When the limiting slide 1 enters the U-shaped tray, the annular groove is engaged on the U-shaped tray. When it moves to the bottom of the corresponding discharge port, the pneumatic cylinder or electric cylinder of the lifting mechanism 2 drives the U-shaped tray to move the lead can body in the limiting slide 1 up and down along the auxiliary slide bar, thereby realizing the up and down movement of the lead can body.

[0017] Furthermore, the solid waste outlet is equipped with a sealing cover, which is connected to a radioactive solid waste temporary storage chamber below, and the sealing cover is used to ensure the airtightness of the upper space.

[0018] Specifically, the sealing cover is made of lead.

[0019] Furthermore, the radioactive solid waste temporary storage chamber includes a hatch 2, a translation mechanism 2, and a lifting mechanism 3; the translation mechanism 2 includes a limiting slide 2, a track 2, and a drive assembly 4; the lifting mechanism 3 also includes a plug-in 2 and a drive assembly 5. The drive assembly 4 of the translation mechanism 2 drives the limiting slide 2 to move on the track 2; the plug-in 2 of the lifting mechanism 3 is fixed to the lower end of the drive assembly 5, which drives the plug-in 2 to move up and down.

[0020] Specifically, the drive component four and the drive component five are selected from pneumatic cylinders or electric cylinders.

[0021] More specifically, when the lead trash can is placed on the limiting slide seat 2, the hatch 2 is closed. At this time, the plug-in 2 is exactly located on the protrusion on the lead trash can cover. The lifting mechanism 3 drives the plug-in 2 to lift the lead trash can cover, thereby realizing the separation operation of the lead trash can cover and the barrel body.

[0022] Furthermore, the opening and closing mechanism at the bottom of the discharge port, hatch one and hatch two are all controlled to open and close by cylinders.

[0023] The packaging protection box is equipped with a clean ventilation system and an online monitoring system, which is suitable for controlling the indoor air pressure to maintain an appropriate pressure gradient. The clean ventilation system includes a high-efficiency filter, a wind speed sensor, etc. The online monitoring system includes a pressure monitor, a radiation monitor, a temperature and humidity monitor, a suspended particle sampling head, and a planktonic bacteria sampler; wherein, the radiation monitor, the temperature and humidity monitor, the suspended particle sampling head, and the planktonic bacteria sampler are installed in the main packaging room, and each functional area is equipped with a pressure monitor; the main packaging room is also provided with a sterilization and disinfection system 1, and the sterilization and disinfection system 1 can be a VHP (vaporized hydrogen peroxide) sterilization system; the material front room and the packaging rear room are also provided with a sterilization and disinfection system 2, and the sterilization and disinfection system 2 includes an ultraviolet lamp.

[0024] Specifically, the packaging protective box is designed to maintain an overall negative pressure, with the air pressure in the main packaging chamber being greater than that in the material front chamber, which in turn is greater than that in the upper space of the rear packaging chamber. The air pressures in the first and second buffer chambers maintain a reasonable pressure gradient with the connected material front chamber, main packaging chamber, and upper space of the rear packaging chamber, typically controlled within a range of 10-50 Pa. The air pressure in the automatic packaging compartment for lead cans and the temporary storage compartment for radioactive solid waste is slightly lower than that in the upper space of the rear packaging chamber.

[0025] Furthermore, the main packaging chamber is also provided with reserved holes suitable for pipeline installation, such as liquid medicine transmission pipelines, reagent transmission pipelines, etc.

[0026] Furthermore, the material front chamber, the main packaging chamber, and the upper space of the packaging rear chamber are all equipped with a double-door structure, the inner layer is a plexiglass door for sealing, and the outer layer is a lead shielding door for radiation protection; the double doors are both provided with operating hand holes, which can cover the indoor operating area, and the lead shielding door is also provided with a lead glass observation window; the packaging protection box is also provided with an inspection door.

[0027] Specifically, an inspection door 1 is provided on the back of the main packaging chamber, an inspection door 2 is provided below the inspection door 1, and an inspection door 3 is provided below the material front chamber.

[0028] The packaging protection box of the utility model realizes automatic control through a PLC system.

[0029] The beneficial effects of the present invention are: 1. Each functional zone of the packaging protection box provided by the present invention can maintain a reasonable pressure difference gradient, and through functions such as clean ventilation, sterilization and disinfection, and online monitoring, each functional zone can reach different cleanliness levels, meeting the requirements of relevant regulations such as China's GMP for clean environment, online monitoring, and data audit tracking in the production process; 2. It has the functions of automatic packaging of lead cans and solid waste collection and storage, which improves the convenience and safety of operation and minimizes the radiation damage to operators; 3. It can also be equipped with an automatic packaging instrument to realize multi-batch continuous packaging of medical isotopes and drugs, thereby improving the utilization efficiency of the packaging protection box. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is an overall schematic diagram of the packaging protection box of Example 1 of the present utility model (left: front, right: back);

[0031] Figure 2 This is a top sectional view of the packaging protection box of Example 1 of the present utility model;

[0032] Figure 3 This is a schematic diagram of the discharge port in Example 1 of the present utility model;

[0033] Figure 4This is a cross-sectional view of the automatic packaging compartment for lead cans in Example 1 of the present utility model;

[0034] Figure 5 This is a partial schematic diagram of the lifting mechanism 1 in Example 1 of the present utility model;

[0035] Figure 6 This is a cross-sectional view of the radioactive solid waste temporary storage chamber in Example 1 of the present utility model;

[0036] Figure 7 This is a top sectional view of the lower space of the packaging rear chamber in Example 1 of the present utility model;

[0037] Wherein, the reference numerals represent:

[0038] 1-Material front room; 2-Main packaging room; 3a-Upper space of the packaging back room; 3b-Lower space of the packaging back room; 4-Buffer room 1; 5-Buffer room 2; 6-Lead glass observation window; 7-Operation hand hole; 81-Inspection door 1; 82-Inspection door 2; 83-Inspection door 3; 9-Plexiglas door; 10-Lead shielding box;

[0039] 21-activity well;

[0040] 31-discharge port; 31a and 31b-discharge ports; 311-opening and closing mechanism; 312-channel;

[0041] 32-Automatic packaging compartment for lead cans; 320-Can body; 3201-Can lid; 321-Hatch door 1; 323-Translation mechanism 1; 3231-Limiting slide 1; 32311-Annular groove; 3232-Track 1; 3241-Plug-in 1; 3242-Drive assembly 2; 3251-U-shaped tray; 3252-Auxiliary slide; 3253-Drive assembly 3;

[0042] 33-Solid waste outlet;

[0043] 34- Radioactive solid waste temporary storage cabin; 340- Lead trash can body; 3401- Lead trash can lid; 341- Hatch door 2; 343- Translation mechanism 2; 3431- Limiting slide 2; 3432- Track 2; 3441- Plug-in 2; 3442- Drive assembly 5;

[0044] 41-front left door; 42-front right door; 51-rear left door; 52-rear right door. DETAILED DESCRIPTION

[0045] The following further illustrates the technical solutions and effects of the present invention with reference to the accompanying drawings and examples, so that those skilled in the art can implement the invention accordingly with reference to the description. It should be understood that the specific embodiments described herein are intended only to illustrate the present invention and are not intended to limit the present invention. The preferred embodiments described below are intended only as examples, and those skilled in the art will readily appreciate other obvious variations.

[0046] In the description of the present invention, it should be noted that the terms "up", "down", "left", "right", "front", "back", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, they cannot be understood as limitations on the present invention.

[0047] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections, electrical connections; direct connections, indirect connections through an intermediate medium, and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on the specific circumstances.

[0048] Example 1

[0049] Combine Figure 1-Figure 7 , the utility model provides the following technical solutions:

[0050] This protective packaging box for medical isotopes and their pharmaceuticals includes a material antechamber 1, a main packaging chamber 2, and a rear packaging chamber. The rear packaging chamber is divided into an upper space 3a and a lower space 3b. The upper space 3a is equipped with a material discharge port 31 and a solid waste outlet 33. The lower space 3b includes an automatic lead can packaging compartment 32 below the discharge port 31 and a radioactive solid waste temporary storage compartment 34 below the solid waste outlet 33. A buffer chamber 1 4 is located between the material antechamber 1 and the main packaging chamber 2, and a buffer chamber 2 5 is located between the main packaging chamber 2 and the upper space 3a of the rear packaging chamber. The material antechamber 1, main packaging chamber 2, and rear packaging chamber are installed within a protective lead shielding box 10.

[0051] A front left door 41 is located between buffer chamber 1 4 and the material front chamber 1, a front right door 42 is located between buffer chamber 1 4 and the main packaging chamber 2, a rear right door 52 is located between buffer chamber 2 5 and the main packaging chamber 2, and a rear left door 51 is located between buffer chamber 2 5 and the upper space 3a of the packaging rear chamber. A track is installed inside buffer chamber 1 4, on which a material tray is mounted, which slides along the track.

[0052] A sunken activity well 21 is installed in the main filling chamber 2.

[0053] The bottom of the discharge port 31 is provided with an opening and closing mechanism 311 and a channel 312. The discharge port can be adapted to vials of different volumes (e.g., 31a: 30 mL; 31b: 10 mL). Figure 3 As shown (the opening and closing mechanism 311 is in the closed state at this time).

[0054] The automatic packaging chamber 32 for lead cans includes a hatch 1 321, a translation mechanism 1 323, and a first and second lifting mechanism. The translation mechanism 1 323 includes a first limiting slide 1 3231, a track 1 3232, and a first drive assembly. The first lifting mechanism includes a first plug 1 3241 and a second drive assembly. The first plug 1 3241 has a latch that fits the can lid 3201. The second lifting mechanism includes a U-shaped tray 3251, an auxiliary slide 3252, and a third drive assembly. The end of the U-shaped tray 3251 facing the hatch 1 321 is open. The auxiliary slide 3252 is fixed within the automatic packaging chamber 32 and extends through both ends of the opening of the U-shaped tray 3251. The outer ring of the first limiting slide 3231 is an annular groove 32311.

[0055] The solid waste opening 33 is provided with a sealing cover, which is connected to a radioactive solid waste temporary storage chamber 34. When the sealing cover is placed on the solid waste opening 33, the sealing cover is in a closed state.

[0056] The radioactive solid waste temporary storage chamber 34 includes a second door 341, a second translation mechanism 343 and a third lifting mechanism; the second translation mechanism 343 includes a second limiting slide 3431, a second track 3432 and a fourth driving component; the third lifting mechanism includes a second plug-in 3441 and a fifth driving component.

[0057] The packaging protective box is equipped with a clean ventilation system and an online monitoring system. The online monitoring system includes a pressure monitor, a radiation monitor, a temperature and humidity monitor, a suspended particle sampling head, and a planktonic bacteria sampler. A VHP sterilization system is also provided in the main packaging chamber 2. Ultraviolet lamps are also provided in the material front chamber 1 and the upper space 3a of the packaging rear chamber.

[0058] The functional areas of the packaging protective box are divided into different zones to ensure different internal cleanliness requirements through clean ventilation systems and online monitoring systems. For example, the material front room 1 maintains a Class B environment, the packaging main room 2 maintains a Class A environment, and the upper space 3a of the packaging rear room maintains a Class B environment.

[0059] The material front chamber 1, the main packaging chamber 2, and the upper space 3a of the packaging rear chamber are all equipped with a double-door structure. The inner layer is a plexiglass door for sealing, and the outer layer is a lead shielding door for radiation protection. At the same time, a pressure leakage monitoring and alarm function is provided; both doors are provided with an operating hand hole 7, and the lead shielding door is also provided with a lead glass observation window 6; an inspection door 81 is provided on the back of the main packaging chamber 2, and an inspection door 82 is provided below the inspection door 81, and an inspection door 83 is provided below the material front chamber 1; the main packaging chamber 2 is also provided with a reserved hole suitable for installing pipelines.

[0060] Working principle:

[0061] Before using the packaging protective box, perform a self-check to ensure that the doors of hatch 1 321, hatch 2 341, and the double doors of the material antechamber 1, main packaging chamber 2, and upper space 3a of the rear packaging chamber are properly closed. The main packaging chamber 2 is sterilized using a VHP sterilization system. The material antechamber 1 and upper space 3a of the rear packaging chamber are sterilized by spraying disinfectant and then using ultraviolet light.

[0062] Then, the can with the can lid 3201 unscrewed (the can lid is still on the can body) is placed into the limit slide 3231 of the can automatic packaging cabin 32, and the cabin door 321 is closed. Figure 4 As shown, the plug-in 1 3241 is located in the gap between the lead can cover 3201 and the lead can body 320, which is the starting position of the lead can.

[0063] When it is necessary to dispense into 10 mL syringe bottles, the lifting mechanism drives the lead can cover 3201 to rise and separate from the lead can body 320, and the translation mechanism 323 drives the lead can body 320 to move to the bottom of the corresponding discharge port 31b. At this time, the lead can body 320 is in a waiting position.

[0064] Materials enter through the material front chamber 1. Open the front left door 41 and place the materials on the material tray in the buffer chamber 1 4. Then close the front left door 41. After the clean ventilation system in the buffer chamber 1 4 has been operating for a period of time, open the front right door 42 through the operating hand hole 7 of the main filling chamber 2. Remove the materials and place them in the main filling chamber 2 for later use. After closing the front right door 42, start the automatic filling machine to start the liquid medicine filling operation.

[0065] After the subpackaging is completed, the product bottle is moved to the top of the discharge port 31b after the activity is detected by the activity well 21. The lifting mechanism 2 drives the lead can body 320 to rise to the bottom of the discharge port 31b. At this time, the lead can body 320 is in the receiving position. The opening and closing mechanism 311 automatically opens, and the product bottle falls into the lead can body 320. The opening and closing mechanism 311 automatically closes. The lifting mechanism 2 drives the lead can body 320 to descend back to the waiting position. The translation mechanism 1 323 drives the lead can body 320 back to the starting position. The plug-in 1 3241 descends, and the lead can cover 3201 is buckled onto the lead can body, completing the automatic cover drop. The hatch 1 321 automatically opens, tightens the lead can cover 3201, and completes the packaging operation.

[0066] When handling solid waste, Figure 6 As shown, the lead waste bin is placed on the second limiting slide 3431, the second hatch 341 is closed, and the second plug-in 3441 drives the lead waste bin lid 3401 to rise and separate from the lead waste bin body 340, which now represents the starting position of the lead waste bin body 340. The second translation mechanism 343 drives the lead waste bin body 340 to below the solid waste opening 33, which represents the use position of the lead waste bin body 340. When solid waste needs to be discarded during the repackaging operation, the sealing lid automatically opens, and the solid waste falls into the lead waste bin body 340, and the sealing lid automatically closes. After the repackaging operation is completed, when the solid waste needs to be disposed of, the second translation mechanism 343 drives the lead waste bin body 340 back to the starting position, and the second plug-in 3441 drives the lead waste bin lid 3401 to descend, completing the automatic lid drop. The second hatch 341 automatically opens, and the lead waste bin is transferred to the temporary storage room for radioactive solid waste.

[0067] In summary, the present invention provides a protective packaging box for medical isotopes and their pharmaceuticals, with each functional area capable of maintaining a reasonable pressure gradient. Furthermore, it features automatic packaging of lead cans and solid waste collection and storage, improving operational convenience and safety while minimizing radiation exposure to operators.

[0068] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A protective box for packaging medical isotopes and their medicines, characterized in that: It includes a material front chamber (1), a main packaging chamber (2) and a packaging back chamber, wherein: The packaging rear chamber is divided into an upper space (3a) and a lower space (3b), wherein the upper space (3a) is provided with a discharge port (31) and a solid waste port (33); the lower space (3b) includes a lead can automatic packaging chamber (32) below the discharge port (31) and a radioactive solid waste temporary storage chamber (34) below the solid waste port (33); A buffer chamber 1 (4) is provided between the material front chamber (1) and the sub-packaging main chamber (2), and a buffer chamber 2 (5) is provided between the sub-packaging main chamber (2) and the upper space (3a) of the packaging rear chamber; The material front chamber (1), the subpackaging main chamber (2), and the packaging rear chamber are installed in a lead shielding box (10) with a protective function.

2. The packaging protection box according to claim 1, characterized in that: A front left door (41) is provided between the buffer chamber 1 (4) and the material front chamber (1), a front right door (42) is provided between the buffer chamber 1 (4) and the sub-packaging main chamber (2), a rear right door (52) is provided between the buffer chamber 2 (5) and the sub-packaging main chamber (2), and a rear left door (51) is provided between the buffer chamber 2 (5) and the upper space (3a) of the packaging rear chamber; a track is provided in the buffer chamber 1 (4), and a material tray is installed on the track to slide along the track.

3. The packaging protection box according to claim 1, characterized in that: A sunken activity well (21) is installed in the main packaging chamber (2).

4. The packaging protection box according to claim 1, characterized in that: An opening and closing mechanism (311) and a channel (312) are provided at the bottom of the discharge port (31), and the channel (312) is connected to the lead can automatic packaging cabin (32).

5. The packaging protection box according to claim 4, characterized in that: The lead can automatic packaging cabin (32) includes a cabin door (321), a translation mechanism (323), a lifting mechanism (1) and a lifting mechanism (2); the translation mechanism (323) includes a limiting slide (3231), a track (3232) and a driving component (1), and the driving component (1) is installed at the bottom of the limiting slide (3231) and can drive the limiting slide (3231) to move on the track (3232); the lifting mechanism (1) includes a plug-in (3241) and a driving component (2) (3242), and the plug-in (3241) has a bayonet adapted to the lead can cover and can act on the lead can cover. The bottom moves up and down to separate the lead can cover and the lead can body; the lifting mechanism 2 includes a U-shaped tray (3251), an auxiliary slide bar (3252) and a drive component 3 (3253), the U-shaped tray (3251) is parallel to the translation mechanism 1 (323), and is open at one end facing the hatch 1 (321), the auxiliary slide bar (3252) is fixed in the lead can automatic packaging cabin (32), and passes through both ends of the opening direction of the U-shaped tray (3251); the outer ring of the limiting slide seat 1 (3231) has an annular groove (32311) that can engage the U-shaped tray (3251).

6. The packaging protection box according to claim 1, characterized in that: The solid waste outlet (33) is provided with a sealing cover, and is connected to a radioactive solid waste temporary storage chamber (34) below.

7. The packaging protection box according to claim 6, characterized in that: The radioactive solid waste temporary storage cabin (34) includes a hatch 2 (341), a translation mechanism 2 (343) and a lifting mechanism 3; the translation mechanism 2 (343) includes a limiting slide 2 (3431), a track 2 (3432) and a driving component 4, and the driving component 4 is installed at the bottom of the limiting slide 2 (3431) and can drive the limiting slide 2 (3431) to move on the track 2 (3432); the lifting mechanism 3 includes a plug-in 2 (3441) and a driving component 5 (3442), and the plug-in 2 (3441) acts on the lead trash can cover and moves up and down to separate the lead trash can cover and the barrel body.

8. The packaging protection box according to claim 1, characterized in that: A clean ventilation system and an online monitoring system are installed in the packaging protection box, and the online monitoring system includes a pressure monitor, a radiation monitor, a temperature and humidity monitor, a suspended particle sampling head, and a planktonic bacteria sampler; a sterilization and disinfection system 1 is also provided in the packaging main chamber (2); and a sterilization and disinfection system 2 is also provided in the material front chamber (1) and the upper space (3a) of the packaging rear chamber.

9. The packaging protection box according to claim 1, characterized in that: The main packaging chamber (2) is also provided with a reserved hole suitable for pipeline installation.

10. The packaging protection box according to claim 1, characterized in that: The material front chamber (1), the main packaging chamber (2) and the upper space (3a) of the packaging rear chamber are all equipped with a double-door structure, the inner layer of which is a plexiglass door and the outer layer is a lead shielding door; the double doors are both provided with an operating hand hole (7), and the lead shielding door is also provided with a lead glass observation window (6); the packaging protective box is also provided with an inspection door.

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