Structure capable of improving paroxetine hydrochloride tablet wet granulation efficiency
By introducing an electric push rod and an arc-shaped scraper into the wet granulator, the problem of adhesion to the inner wall during granulation is solved, achieving automated cleaning and efficient mixing, and improving the granulation efficiency of paroxetine hydrochloride tablets.
Patent Information
- Application Number
- CN202421282964.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-06
- Publication Date
- 2025-12-23
- Estimated Expiration
- 2034-06-06
AI Technical Summary
In existing wet granulation machines, the material and binder tend to adhere to the inner wall of the granulation chamber during the granulation process, resulting in uneven mixing, requiring manual handling, and reducing granulation efficiency.
The combination of electric push rod and arc scraper automatically cleans the deposits on the inner wall of the granulation box, and the design of automatic stirring rod and scraper improves mixing efficiency.
It achieves automated cleaning of deposits on the inner wall, avoiding manual intervention and improving the efficiency and mixing effect of wet granulation of paroxetine hydrochloride tablets.
Smart Images
Figure CN223696364U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to hydrochloric acid paroxetine tablet production technical field, more particularly to a structure that can promote hydrochloric acid paroxetine tablet wet granulation efficiency. BACKGROUND
[0002] Hydrochloric acid paroxetine tablet is a kind of drug for treating various mental diseases, it can relieve depressive symptoms, such as fatigue, sleep disorder, lack of interest and pleasure in daily activities, anorexia etc.
[0003] In the production process of hydrochloric acid paroxetine tablet, granulator is needed to form, and existing granulator is divided into dry method and wet method two, for hydrochloric acid paroxetine tablet production, wet granulator is needed, and wet granulator is a kind of equipment for making powder or granular material into granular or spherical particle. Its main working principle is to use wet granulation technology, under the environment of wetting, by adding binder (such as liquid) to make material form good fluidity mixture, then through the mixer and movement device in wet granulator, material forms granular, but there is certain deficiency in the use of existing wet granulator, for example, material needs to be added in the granulation process, and certain viscosity will appear when material combines with binder, then the mixture of viscosity is easy to adhere to the inner wall of granulation box in the stirring process, if not timely processing, it will be stirred and mixed, so more time is needed for stirring, if processing, manual operation is mostly adopted, at this time, the stirring speed needs to be reduced to avoid injury to manual operation, and the occurrence of the two conditions will reduce mixing effect, increase stirring mixing time, lead to the reduction of subsequent granulation efficiency. UTILITY MODEL CONTENTS
[0004] The utility model aims at providing a structure that can promote hydrochloric acid paroxetine tablet wet granulation efficiency, to solve the above-mentioned equipment in prior art when using, material needs to be added in the granulation process, and certain viscosity will appear when material combines with binder, then the mixture of viscosity is easy to adhere to the inner wall of granulation box in the stirring process, if not timely processing, it will be stirred and mixed, so more time is needed for stirring, if processing, manual operation is mostly adopted, at this time, the stirring speed needs to be reduced to avoid injury to manual operation, and the occurrence of the two conditions will reduce mixing effect, increase stirring mixing time, lead to the reduction of subsequent granulation efficiency.
[0005] To achieve the above object, the utility model provides the following technical scheme: A structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted, including granulator body, the top of granulator body is installed control panel, the top of granulator body and the side of control panel are connected with granulating box, the top of granulating box is connected with first feed inlet and second feed inlet correspondingly, the bottom of granulating box outside wall is connected with discharge gate, the inside of granulating box is provided with stirring assembly, the outside wall close to the top of granulating box is connected with mounting plate, the top of mounting plate is installed with electric push rod, the inside of granulating box is provided with arc scraper, stirring assembly includes motor and stirring rod, the bottom of granulating box is installed with motor, the inside of granulating box is provided with stirring rod.
[0006] As a structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted of the utility model, the output shaft of motor extends to the inside of granulating box and is connected with stirring rod outside wall, and stirring rod is connected with rotating between motor and granulating box.
[0007] As a structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted of the utility model, the size of arc scraper is same with the size of the inside of granulating box, and the top of arc scraper is connected with the telescopic end of electric push rod, and arc scraper is connected with lifting between electric push rod and granulating box.
[0008] As a structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted of the utility model, the bottom of the side wall of granulator body and discharge gate is provided with receiving box, the side wall of granulator body is installed with butt joint block, the outside wall of receiving box is integrally connected with protruding block, the bottom of butt joint block is integrally connected with fixed block.
[0009] As a structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted of the utility model, the inside of fixed block is inserted with fixed rod, and the surface of fixed rod is sleeved with spring.
[0010] As a structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted of the utility model, fixed rod is connected with elastic extension between spring and fixed block.
[0011] Compared with the prior art, the utility model has the beneficial effects that:
[0012] The utility model discloses a cooperation of electric push rod and arc scraper, makes arc scraper be movable in the inside of granulating box, and then the material adhered to the inside wall of granulating box is cleaned, personnel cleaning needs to reduce the mixing speed, and the material adhered to the inside wall of granulating box also influences the mixing effect, needs to stir mixes longer time, and then the cleaning of the material adhered to the inside wall of granulating box is cleaned, improves the wet granulation efficiency of paroxetine hydrochloride tablet, and then utilizes the receiving box and can receive the paroxetine hydrochloride tablet of forming, thereby the convenient effect of receiving material is played. BRIEF DESCRIPTION OF DRAWINGS
[0013] The accompanying drawings are included to provide a further understanding of the present application and are incorporated in and constitute a part of this specification, illustrate embodiments of the present application and are used to explain the present application, and do not constitute a limitation on the present application. In the drawings:
[0014] Figure 1 It is the main body structure schematic diagram of the utility model;
[0015] Figure 2 It is the main body overhead structure schematic diagram of the utility model;
[0016] Figure 3 It is the granulating box section structure schematic diagram of the utility model;
[0017] Figure 4 It is the receiving box connection split structure schematic diagram of the utility model;
[0018] Figure 5 It is the fixed block section structure schematic diagram of the utility model.
[0019] In the drawing: 1, granulator body;2, control panel;3, granulating box;4, first feed inlet;5, second feed inlet;6, discharge port;7, motor;8, stirring rod;9, mounting plate;10, electric push rod;11, arc scraper;12, receiving box;13, lug;14, butt joint block;15, fixed block;16, fixed rod;17, spring. DETAILED DESCRIPTION
[0020] The technical scheme in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.
[0021] Embodiment one
[0022] Please refer to Figures 1-5The utility model provides the following technical scheme: A structure of wet granulation efficiency of paroxetine hydrochloride tablet can be promoted, including granulator body 1, the top of granulator body 1 is equipped with control panel 2, the model of control panel 2 is SIEMENS / Siemens, and the top of granulator body 1 is connected with granulating box 3 on the side of control panel 2, and the top of granulating box 3 is connected with first feed inlet 4 and second feed inlet 5 correspondingly, and the bottom of the outer wall of granulating box 3 is connected with discharge gate 6, and the inside of granulating box 3 is provided with stirring subassembly, and the outer wall close to the top of granulating box 3 is connected with mounting plate 9, and the top of mounting plate 9 is equipped with electric push rod 10, and the inside of granulating box 3 is provided with arc scraper 11, and stirring subassembly includes motor 7 and stirring rod 8, and motor 7 is installed at the bottom of granulating box 3, and stirring rod 8 is arranged in the inside of granulating box 3.
[0023] Preferably: the output shaft of motor 7 extends to the inside of granulating box 3 and is connected with stirring rod 8 on the outer wall, and stirring rod 8 is rotatably connected between motor 7 and granulating box 3.
[0024] Preferably: the size of arc scraper 11 is same with the size of the inside of granulating box 3, and the top of arc scraper 11 is connected with the telescopic end of electric push rod 10, and arc scraper 11 is liftably connected between electric push rod 10 and granulating box 3.
[0025] In the embodiment, the use of arc scraper 11 is described, first, the granulator body 1 is started through the control panel 2, then the material of paroxetine hydrochloride tablet is sent into the granulating box 3 through the first feed inlet 4, then the motor 7 is started to work, then the output shaft of motor 7 drives the stirring rod 8 to rotate in the inside of the granulating box 3, and then the material of paroxetine hydrochloride tablet is stirred, then the binder is sent from the second feed inlet 5, and then mixed with the material of paroxetine hydrochloride tablet to form paroxetine hydrochloride tablet, at this time, if it is needed to clean the inner wall of the granulating box 3, the electric push rod 10 is started to work, and then the telescopic end of the electric push rod 10 is extended to push the arc scraper 11 to move downward, then the arc scraper 11 moves downward to scrape off the material of paroxetine hydrochloride tablet attached to the inner wall of the granulating box 3, thereby avoiding the increase of stirring and mixing time and the influence of stirring effect caused by the existing processing of the material of paroxetine hydrochloride tablet attached to the inner wall of the granulating box 3, thereby improving the wet granulation efficiency of paroxetine hydrochloride tablet.
[0026] Example two
[0027] Please refer to Figures 1-5 The side wall of the granulator body 1 and located at the bottom of the discharge gate 6 is provided with a receiving box 12, the side wall of the granulator body 1 is provided with a butt joint block 14, the outer side wall of the receiving box 12 is integrally connected with a protruding block 13, and the bottom of the butt joint block 14 is integrally connected with a fixed block 15.
[0028] Preferably, the inner part of the fixed block 15 is inserted with the fixed rod 16, and the surface of the fixed rod 16 is sleeved with the spring 17.
[0029] Preferably, the fixed rod 16 is elastically connected with the fixed block 15 through the spring 17.
[0030] In the embodiment, according to the description of the first embodiment, after the paroxetine hydrochloride tablets are completed by the wet method, the rotation speed of the stirring rod 8 is reduced, then the paroxetine hydrochloride tablets are sent into the discharge port 6 and then fall into the receiving box 12 for storage, thereby playing a convenient receiving role. When the receiving box 12 is full, the fixed rod 16 needs to be pulled, then the fixed rod 16 extrudes the spring 17 to shrink, then the fixed rod 16 is received in the inner part of the fixed block 15 from the inner part of the butt joint block 14, and the locking cooperation between the protruding block 13 and the butt joint block 14 is released, then the receiving box 12 is pulled outwards, and finally the paroxetine hydrochloride tablets in the inner part of the receiving box 12 are uniformly processed.
[0031] In summary, according to the description of the first and second embodiments, the cooperation of the electric push rod 10 and the arc-shaped scraper 11 allows the arc-shaped scraper 11 to move up and down in the inner part of the granulating box 3, thereby cleaning the materials attached to the inner wall of the granulating box 3, avoiding the need to reduce the stirring and mixing speed for personnel cleaning, and avoiding the situation that the materials attached to the inner wall of the granulating box 3 affect the mixing effect and need to stir and mix for a longer time, thereby improving the wet granulation efficiency of the paroxetine hydrochloride tablets through the cleaning of the materials attached to the inner wall of the granulating box 3, and then using the receiving box 12 to collect the formed paroxetine hydrochloride tablets, thereby playing a convenient receiving role.
[0032] Finally, it should be noted that the above description is only preferred embodiments of the present application and is not used to limit the present application. Although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or equivalently replace some technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.
Claims
1. A structure for improving the wet granulation efficiency of paroxetine hydrochloride tablets, comprising a granulator body (1), characterized in that: The top of the pelletizing machine body (1) is equipped with a control panel (2). The top of the pelletizing machine body (1) and one side of the control panel (2) are connected to a pelleting box (3). The top of the pelleting box (3) is connected to a first feed port (4) and a second feed port (5). The bottom of the outer wall of the pelleting box (3) is connected to a discharge port (6). The inside of the pelleting box (3) is equipped with a stirring assembly. The outer wall of the pelleting box (3) near the top is connected to a mounting plate (9). The top of the mounting plate (9) is equipped with an electric push rod (10). The inside of the pelleting box (3) is equipped with an arc-shaped scraper (11). The stirring assembly consists of a motor (7) and a stirring rod (8). The motor (7) is installed at the bottom of the granulation box (3), and the stirring rod (8) is located inside the granulation box (3).
2. The structure according to claim 1 that can improve the wet granulation efficiency of paroxetine hydrochloride tablets, characterized in that: The output axis of the motor (7) extends into the granulation box (3) and is connected to the stirring rod (8) on the outer side wall. The stirring rod (8) is rotatably connected to the granulation box (3) through the motor (7).
3. The structure according to claim 1 that can improve the wet granulation efficiency of paroxetine hydrochloride tablets, characterized in that: The size of the arc-shaped scraper (11) is the same as the size of the inside of the granulation box (3), and the top of the arc-shaped scraper (11) is connected to the telescopic end of the electric push rod (10), and the arc-shaped scraper (11) forms a lifting connection with the granulation box (3) through the electric push rod (10).
4. The structure according to claim 1 that can improve the wet granulation efficiency of paroxetine hydrochloride tablets, characterized in that: A receiving box (12) is provided on the side wall of the granulator body (1) and at the bottom of the discharge port (6). A docking block (14) is installed on the side wall of the granulator body (1). A protrusion (13) is integrally connected to the outer side wall of the receiving box (12). A fixing block (15) is integrally connected to the bottom of the docking block (14).
5. The structure according to claim 4 that can improve the wet granulation efficiency of paroxetine hydrochloride tablets, characterized in that: A fixing rod (16) is inserted inside the fixing block (15), and a spring (17) is sleeved on the surface of the fixing rod (16).
6. The structure according to claim 5 that can improve the wet granulation efficiency of paroxetine hydrochloride tablets, characterized in that: The fixed rod (16) is elastically telescopically connected to the fixed block (15) via a spring (17).