Anti-shaking fluorescent immunochromatographic kit
By designing a shake-resistant fluorescence immunochromatographic reagent kit, the problems of shaking and impurities were solved by using a limiting and sealing structure, which enhanced the stability of detection and chromatography efficiency, and achieved high-efficiency fluorescence immunochromatographic detection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- ZHENGZHOU DONGGE BIOENGINEERING TECH RES INST CO LTD
- Filing Date
- 2025-05-08
- Publication Date
- 2026-06-09
AI Technical Summary
Fluorescent immunochromatographic reagent kits are prone to shaking during use, which can lead to solution leakage and affect the detection results due to impurities, resulting in insufficient stability and detection efficiency.
A shake-resistant fluorescence immunochromatographic reagent kit was designed, comprising a placement box, a detection box, a limiting seat, a support seat, an anti-slip pad, and a limiting groove. The detection box is fixed by limiting the movement, and combined with a cover plate and sealing structure, it prevents shaking and impurities from entering, thereby enhancing stability and protection. Furthermore, the chromatography efficiency is improved by using a hydrophilic modified membrane.
This achieves stability and protection in detection, avoids the influence of shaking and impurities, and improves the stability and chromatography efficiency of detection.
Smart Images

Figure CN224341542U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of immunoassay technology, specifically to a shake-resistant fluorescent immunochromatographic reagent kit. Background Technology
[0002] Fluorescent immunochromatography is a novel immunoassay technique that combines multiple disciplines such as immunology, fluorescence, and biochemistry. It has the advantages of high sensitivity, high specificity, speed, and simplicity. Fluorescent immunochromatography kits combine the speed of immunochromatography with the high sensitivity of fluorescent labeling and are widely used in fields such as medical diagnostics, food safety, and environmental monitoring.
[0003] Most fluorescent immunochromatographic reagent kits are used by hand or placed flat on a table. It is inconvenient to limit the position of the kit during use. When the fluorescent immunoassay solution is dropped into the inside of the kit, the excess solution can easily leak out and cause contamination. Kits exposed to the outside for chromatography are prone to impurities entering and affecting the test results.
[0004] There is an urgent need for a shake-resistant fluorescence immunochromatographic reagent kit to address the technical deficiencies mentioned above. Utility Model Content
[0005] The purpose of this invention is to provide a shake-resistant fluorescence immunochromatographic reagent kit to solve the problem of poor stability mentioned in the background art.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a shake-resistant fluorescence immunochromatographic reagent kit, comprising a placement box and a detection box. The detection box contains a test strip, a sample pad, and an absorption pad. The top of the detection box is provided with a sample dispensing port and a display area. A support base is installed at the center of the top of the placement box. A limiting seat is installed at the edge of the interior of the placement box. Six sets of limiting grooves are provided at the top of both the support base and the limiting seat. A first cover plate is installed on the left side of the top of the placement box, and a second cover plate is installed on the right side of the top of the placement box. An anti-slip pad is fixedly connected to the bottom of the placement box.
[0007] As a further technical solution of this utility model, the detection box is provided in six sets, and the detection box is embedded in the limiting groove.
[0008] As a further technical solution of this utility model, the anti-slip pad is made of silicone material, and the bottom of the anti-slip pad is uniformly provided with anti-slip texture.
[0009] As a further technical solution of this utility model, the display area is disposed above the test strip, and the test strip is made of nitrocellulose membrane.
[0010] As a further technical solution of this utility model, the surface of the test strip is provided with a hydrophilic modified film, and the test strip is provided with detection lines and quality control lines.
[0011] As a further technical solution of this utility model, the sample application port is located above the sample pad.
[0012] As a further technical solution of this utility model, the first cover plate is provided with a splicing slot inside, and the second cover plate is fixedly connected with a splicing block, and a handle is installed on the top of the splicing block.
[0013] As a further technical solution of this utility model, the splicing block is embedded inside the splicing slot in a fitted connection, and both the splicing block and the splicing slot are provided with sealing strips on their exteriors.
[0014] Compared with the prior art, the beneficial effects of this utility model are: the anti-shaking fluorescent immunochromatographic reagent kit not only achieves the function of avoiding shaking and improving stability, and the function of enhancing the protective effect, but also the function of enhancing the chromatography efficiency;
[0015] (1) By setting up a placement box, a limiting seat, a detection box, a support seat, an anti-slip pad, and a limiting groove, six sets of detection boxes are placed inside the placement box before detection. The detection boxes can be tightly embedded inside the limiting groove to achieve limiting and fixing. When adding fluorescent immunoassay solution, excess liquid can fall into the placement box and be collected to prevent outflow. The anti-slip pad at the bottom of the placement box can improve the stability of the placement box. The detection boxes embedded inside the placement box can prevent shaking, thereby achieving a stable detection effect. After the detection is completed, the detection boxes can be removed and the inside of the placement box can be cleaned. This structure realizes the function of facilitating stable detection.
[0016] (2) By setting a first cover plate, splicing block, second cover plate, splicing slot and handle, the fluorescent immunoassay solution is dripped into the six groups of test strips one by one, and then the first cover plate and second cover plate are closed and sealed to the top of the box. When the first cover plate and second cover plate are closed, the splicing block is embedded in the splicing slot to achieve splicing and fixation. The first cover plate and second cover plate can prevent external impurities from entering the sample port and affecting the test results. This structure realizes the function of facilitating the enhancement of protection effect.
[0017] (3) By setting up a detection box, test paper, sample pad, absorption pad and sample dispensing port, when performing fluorescence immunochromatographic detection, it is necessary to first use a dripper to drip the fluorescence immunoassay sample solution into the inside of the sample dispensing port. The fluorescence immunoassay solution enters the sample pad and gradually wets the test paper and absorption pad. The hydrophilic modified film added to the surface of the test paper can reduce non-specific adsorption, thereby enhancing the chromatographic efficiency of the test paper. This structure realizes the function of facilitating the enhancement of chromatographic efficiency. Attached Figure Description
[0018] Figure 1 This is a front view cross-sectional structural diagram of the present invention;
[0019] Figure 2 This is a top view cross-sectional structural diagram of the present invention;
[0020] Figure 3 This is a top view of the structure of this utility model;
[0021] Figure 4 This is a top view of the detection box of this utility model.
[0022] In the diagram: 1. Placement box; 2. Limiting seat; 3. Detection box; 4. Test paper; 5. First cover plate; 6. Sample pad; 7. Splicing block; 8. Second cover plate; 9. Support base; 10. Absorbent pad; 11. Anti-slip pad; 12. Sample dispensing port; 13. Display area; 14. Limiting groove; 15. Splicing slot; 16. Handle. Detailed Implementation
[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0024] Please see Figure 1-4 An embodiment of this utility model provides: a shake-resistant fluorescence immunochromatographic reagent kit, including a placement box 1 and a detection box 3. The detection box 3 is equipped with a test strip 4, a sample pad 6 and an absorption pad 10. The top of the detection box 3 is provided with a sample dispensing port 12 and a display area 13. A support seat 9 is installed at the middle position of the top of the placement box 1. A limiting seat 2 is installed at the edge of the inside of the placement box 1. The top of the support seat 9 and the top of the limiting seat 2 are provided with six sets of limiting grooves 14. A first cover plate 5 is installed on the left side of the top of the placement box 1. A second cover plate 8 is installed on the right side of the top of the placement box 1. An anti-slip pad 11 is fixedly connected to the bottom of the placement box 1.
[0025] The detection box 3 is set with six sets. The detection box 3 is embedded in the limiting groove 14. The anti-slip pad 11 is made of silicone material and the bottom of the anti-slip pad 11 is evenly provided with anti-slip texture.
[0026] Specifically, such as Figure 1 and Figure 2As shown, before testing, six test boxes 3 are placed inside the placement box 1. The test boxes 3 can be tightly embedded in the limiting groove 14 to achieve limiting and fixation. When adding the fluorescent immunoassay solution, excess liquid can fall into the placement box 1 for collection and to prevent leakage. The anti-slip pad 11 at the bottom of the placement box 1 can improve the stability of the placement box 1. The test boxes 3 embedded inside the placement box 1 can prevent shaking, thereby achieving a stable testing effect. After the test is completed, the test boxes 3 can be removed and the inside of the placement box 1 can be cleaned.
[0027] The display area 13 is located above the test strip 4. The test strip 4 is made of nitrocellulose membrane and has a hydrophilic modified membrane on its surface. The test strip 4 has detection lines and control lines. The sample application port 12 is located above the sample pad 6.
[0028] Specifically, such as Figure 1 and Figure 4 As shown, during fluorescence immunochromatographic detection, the fluorescence immunoassay sample solution needs to be dripped into the sample inlet 12 using a drip irrigation system. The fluorescence immunoassay solution then enters the sample pad 6 and gradually wets the test paper 4 and the absorption pad 10. The hydrophilic modified membrane added to the surface of the test paper 4 can reduce non-specific adsorption, thereby enhancing the chromatographic efficiency of the test paper 4.
[0029] The first cover plate 5 has a splicing slot 15 inside, and a splicing block 7 is fixedly connected to the second cover plate 8. A handle 16 is installed on the top of the splicing block 7. The splicing block 7 is embedded in the splicing slot 15 and is connected in a fitted manner. Both the splicing block 7 and the splicing slot 15 are provided with sealing strips on the outside.
[0030] Specifically, such as Figure 1 and Figure 3 As shown, after the fluorescent immunoassay solution is dripped into the six test strips 4 one by one, the first cover plate 5 and the second cover plate 8 are closed and sealed to the top of the placement box 1. When the first cover plate 5 and the second cover plate 8 are closed, the splicing block 7 is embedded in the splicing slot 15 to achieve splicing and fixation. The first cover plate 5 and the second cover plate 8 can prevent external impurities from entering the sample inlet 12 and affecting the test results.
[0031] Working principle: In use, before fluorescence immunochromatographic detection, the six test boxes 3 are placed inside the placement box 1. The test boxes 3 are tightly embedded in the limiting groove 14 for positioning and fixation. The anti-slip pad 11 at the bottom of the placement box 1 improves the stability of the placement box 1. The test boxes 3 are embedded inside the placement box 1 to prevent shaking. The fluorescence immunochromatographic sample solution needs to be dripped into the sample inlet 12 using a drip applicator. When adding the fluorescence immunochromatographic solution, excess liquid can fall into the placement box 1 for collection to prevent outflow. The fluorescence immunochromatographic solution enters the sample pad 6 and gradually wets the test paper 4 and the absorption pad. 10. The hydrophilic modified membrane added to the surface of the test strip 4 can reduce non-specific adsorption, thereby enhancing the chromatography efficiency of the test strip 4. After the fluorescent immunoassay solution is dripped into the six sets of test strips 4 one by one, the first cover plate 5 and the second cover plate 8 are closed and sealed to the top of the placement box 1. When the first cover plate 5 and the second cover plate 8 are closed, the splicing block 7 is embedded in the splicing slot 15 to achieve splicing and fixation. The first cover plate 5 and the second cover plate 8 can prevent external impurities from entering the sample port 12 and affecting the test results, thereby achieving a stable test effect. After the test is completed, the test box 3 can be removed and the inside of the placement box 1 can be cleaned.
[0032] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.
Claims
1. A shake-resistant fluorescence immunochromatographic assay kit, comprising a placement box (1) and a detection box (3), characterized in that: The test box (3) is equipped with a test strip (4), a sample pad (6) and an absorption pad (10) respectively. The top of the test box (3) is provided with a sample inlet (12) and a display area (13). A support base (9) is installed at the middle position of the top of the placement box (1). A limiting seat (2) is installed at the edge of the inside of the placement box (1). The top of the support base (9) and the top of the limiting seat (2) are provided with six sets of limiting grooves (14). A first cover plate (5) is installed on the left side of the top of the placement box (1). A second cover plate (8) is installed on the right side of the top of the placement box (1). An anti-slip pad (11) is fixedly connected to the bottom of the placement box (1).
2. The anti-shake fluorescent immunochromatographic assay kit according to claim 1, characterized in that: The detection box (3) is provided in six sets, and the detection box (3) is embedded in the limiting groove (14).
3. The anti-shake fluorescent immunochromatographic reagent kit according to claim 1, characterized in that: The anti-slip mat (11) is made of silicone material, and the bottom of the anti-slip mat (11) is uniformly provided with anti-slip texture.
4. The anti-shake fluorescent immunochromatographic reagent kit according to claim 1, characterized in that: The display area (13) is positioned above the test strip (4), which is made of nitrocellulose membrane.
5. The anti-shake fluorescence immunochromatographic assay kit according to claim 1, characterized in that: The surface of the test strip (4) is provided with a hydrophilic modified film, and the test strip (4) is provided with a detection line and a quality control line.
6. The anti-shake fluorescence immunochromatographic reagent kit according to claim 1, characterized in that: The sample inlet (12) is located above the sample pad (6).
7. The anti-shake fluorescence immunochromatographic reagent kit according to claim 1, characterized in that: The first cover plate (5) has a splicing slot (15) inside, and the second cover plate (8) is fixedly connected to a splicing block (7), and a handle (16) is installed on the top of the splicing block (7).
8. The anti-shake fluorescence immunochromatographic reagent kit according to claim 7, characterized in that: The splicing block (7) is embedded inside the splicing slot (15) in a fitted connection, and both the splicing block (7) and the splicing slot (15) are provided with sealing strips on the outside.