A cell culture flask in-vivo monitoring patch assembly

Abstract

The utility model discloses a cell culture bottle inner environment parameter visual monitoring patch assembly, including operation platform and moving plate, the utility model discloses a moving plate is set up in the operation platform lateral wall, and one lateral wall of moving plate is provided with monitoring device, and the other lateral wall is installed with the monitoring probe that is connected with monitoring device, and the lateral wall of moving plate is installed with the extension spring, and the other end of extension spring is connected with operation platform, when using, the moving plate is pulled away from operation platform, and the cell culture bottle that is attached with the patch is placed in the operation platform top, and the extension spring pulls the moving plate and moves to the operation platform direction, and the monitoring probe is extruded in the cell culture bottle outer wall, and the cell culture bottle of different size can be monitored conveniently.

Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, specifically to a patch assembly for visual monitoring of environmental parameters inside a cell culture flask. Background Technology

[0002] Cell culture refers to a method of enabling organisms to survive, grow, reproduce, and maintain their main structures and functions by simulating the in vivo environment (sterile, suitable temperature, pH, and certain nutritional conditions, etc.) outside the body. Cell culture is also called cell cloning technology, and the formal term in biology is cell culture technique. Whether for bioengineering as a whole or for biological cloning technology, cell culture is an indispensable process; cell culture itself is the large-scale cloning of cells.

[0003] Oxygen monitoring patches are often used to monitor the internal environment of cell culture flasks. However, existing cell culture flask patch monitoring devices have the following problems: 1. Due to the different sizes of cell culture flasks, the monitoring probe of the monitoring device is fixed in position, which is inconvenient to attach to cell culture flasks of different sizes; 2. Existing monitoring devices lack a fixing structure for cell culture flasks. If the position of the cell culture flask changes during monitoring, it can easily affect the monitoring effect. Summary of the Invention

[0004] The purpose of this section is to outline some aspects of the embodiments of this utility model and to briefly introduce some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be used to limit the scope of this utility model.

[0005] In view of the problems existing in the above and / or the existing cell culture flask environmental parameter visualization monitoring patch assembly, this utility model is proposed.

[0006] Therefore, the purpose of this utility model is to provide a visual monitoring patch assembly for environmental parameters inside cell culture flasks. By setting a movable plate on the side wall of the operating table, a monitoring device is set on one side wall of the movable plate, and a monitoring probe connected to the monitoring device is installed on the other side wall. A tension spring is installed on the side wall of the movable plate, and the other end of the tension spring is connected to the operating table. In use, the movable plate is pulled away from the operating table, and the cell culture flask with the patch attached is placed on the top of the operating table. The tension spring pulls the movable plate towards the operating table, pressing the monitoring probe against the outer wall of the cell culture flask. This allows for convenient monitoring of cell culture flasks of different sizes.

[0007] To solve the above-mentioned technical problems, according to one aspect of the present invention, the present invention provides the following technical solution:

[0008] A visualization and monitoring patch component for environmental parameters within a cell culture flask, comprising:

[0009] The operating table has guide grooves on its symmetrical sidewalls, which extend to both sides of the operating table.

[0010] A movable plate is located on the side wall of the operating table. A monitoring device is installed on the side wall of the movable plate. A monitoring probe is installed on the other side wall of the movable plate above the operating table. The monitoring probe is connected to the monitoring device. Multiple tension springs are installed on the side wall of the movable plate at positions corresponding to the operating table. The other end of each tension spring is connected to the side wall of the operating table. Side plates are installed on the symmetrical side walls of the movable plate. The side plates are located on the side wall of the operating table. A ring of rubber blocks is installed on the outer wall of the monitoring probe. Multiple rubber blocks are evenly distributed on the outer wall of the monitoring probe. A guide plate is installed on the inner wall of the side plate. The guide plate is located inside the guide groove.

[0011] As a preferred embodiment of the cell culture flask internal environmental parameter visualization monitoring patch assembly described in this utility model, two fixing plates are symmetrically installed on the top of the operating table, one of the fixing plates has a knob rotatably connected to its side wall, and a threaded rod with positive and negative threads is rotatably connected between the two fixing plates, and the threaded rod with positive and negative threads is coaxially and fixedly connected to the knob.

[0012] As a preferred embodiment of the cell culture flask internal environmental parameter visualization monitoring patch assembly described in this utility model, it further includes clamps, wherein there are two clamps symmetrically located between the two fixed plates, anti-slip pads are installed on the side walls of the clamps, and threaded holes are opened on the side walls of the clamps, through which the positive and negative threaded rods rotate.

[0013] As a preferred embodiment of the cell culture flask internal environmental parameter visualization monitoring patch assembly described in this utility model, a guide rod guide hole is installed between the two fixed plates.

[0014] As a preferred embodiment of the cell culture flask internal environmental parameter visualization monitoring patch assembly described in this utility model, the side wall of the clamping plate is provided with a guide hole, and the guide rod passes through the guide hole.

[0015] As a preferred embodiment of the cell culture flask internal environmental parameter visualization monitoring patch assembly described in this utility model, it further includes a base, which is installed at the bottom of the operating table. The base has mounting plates installed on its symmetrical side walls, and the mounting plates have screw holes on their tops.

[0016] Compared with existing technologies: By installing a movable plate on the side wall of the operating table, with a monitoring device on one side wall and a monitoring probe connected to the monitoring device on the other side wall, and a tension spring installed on the side wall of the movable plate, with the other end of the tension spring connected to the operating table, the movable plate is pulled away from the operating table during use. The cell culture flask with the patch attached is placed on top of the operating table, and the tension spring pulls the movable plate towards the operating table, pressing the monitoring probe against the outer wall of the cell culture flask. This allows for convenient monitoring of cell culture flasks of different sizes. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the present utility model will be described in detail below with reference to the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them:

[0018] Figure 1 This is an overall structural diagram of a cell culture flask internal environmental parameter visualization monitoring patch assembly according to the present invention;

[0019] Figure 2 This is a partial structural diagram of a patch assembly for visual monitoring of environmental parameters inside a cell culture flask according to the present invention;

[0020] Figure 3 This is a partial structural diagram of a patch assembly for visual monitoring of environmental parameters inside a cell culture flask, according to the present invention. Detailed Implementation

[0021] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0022] Secondly, this utility model is described in detail with reference to the schematic diagrams. When describing the embodiments of this utility model, for ease of explanation, the cross-sectional views showing the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of this utility model. In addition, in actual manufacturing, the three-dimensional spatial dimensions of length, width, and depth should be included.

[0023] To make the objectives, technical solutions, and advantages of this utility model clearer, the embodiments of this utility model will be described in further detail below with reference to the accompanying drawings.

[0024] This invention provides a visual monitoring patch assembly for environmental parameters inside cell culture flasks. A movable plate is installed on the side wall of the operating table. A monitoring device is mounted on one side wall of the movable plate, and a monitoring probe connected to the monitoring device is installed on the other side wall. A tension spring is installed on the side wall of the movable plate, with the other end of the spring connected to the operating table. In use, the movable plate is pulled away from the operating table, and the cell culture flask with the patch attached is placed on top of the operating table. The tension spring pulls the movable plate towards the operating table, pressing the monitoring probe against the outer wall of the cell culture flask. This allows for convenient monitoring of cell culture flasks of different sizes.

[0025] Example 1

[0026] Regarding the problem 1 mentioned above: Since different cell culture flasks have different sizes, the monitoring probe of the monitoring device has a fixed position, which is inconvenient to attach to cell culture flasks of different sizes.

[0027] The solution is as follows: This embodiment of a cell culture flask internal environmental parameter visualization monitoring patch component includes an operating table 100 and a moving plate 200.

[0028] The operating table 100 has guide grooves 110 on its symmetrical sidewalls. The guide grooves 110 extend to both sides of the operating table 100. Not shown in the figure, the top of the operating table 100 is provided with an anti-slip pad, which can increase the friction between the bottom of the cell culture flask and the top of the operating table 100, and at the same time buffer the bottom of the operating table 100 and the culture flask to prevent collisions.

[0029] A movable plate 200 is located on the side wall of the operating table 100. A monitoring device is installed on the side wall of the movable plate 200. A monitoring probe 210 is installed on the other side wall of the movable plate 200 above the operating table 100. The monitoring probe 210 is connected to the monitoring device. Multiple tension springs 220 are installed on the side wall of the movable plate 200 at positions corresponding to those on the operating table 100. The other end of each tension spring 220 is connected to the side wall of the operating table 100. Side plates 230 are installed on the symmetrical side walls of the movable plate 200, located on the side walls of the operating table 100. A ring of rubber blocks 240 is installed on the outer wall of the monitoring probe 210. Multiple rubber blocks 240 are evenly distributed on the outer wall of the monitoring probe 210. A guide plate 250 is installed on the inner wall of the side plate 230. Located inside the guide groove 110, when in use, first pull the moving plate 200 to move the monitoring probe 210 away from the operating table 100. When the moving plate 200 moves, the tension spring 220 is stretched. After placing the cell culture flask with the oxygen-measuring patch attached on top of the operating table 100, the moving plate 200 is released. The tension spring 220 rebounds and pushes the moving plate 200 and the monitoring probe 210 towards the operating table 100 until the rubber block 240 abuts against the outer wall of the cell culture flask. The monitoring probe 210 then performs monitoring. The rubber block 240 is used to prevent the monitoring probe 210 from directly contacting the wall of the cell culture flask. When the moving plate 200 slides, the guide plate 250 slides inside the guide groove 110 to guide the moving plate 200.

[0030] Example 2

[0031] Regarding the second problem to be solved above: the existing monitoring device lacks a fixing structure for the cell culture flask. If the position of the cell culture flask changes during monitoring, it can easily affect the monitoring effect.

[0032] The solution is as follows: The cell culture flask internal environmental parameter visualization monitoring patch assembly of this embodiment also includes a clamp 300 and a base 400.

[0033] Two fixed plates 120 are symmetrically mounted on the top of the operating table 100. A knob 130 is rotatably connected to the side wall of one of the fixed plates 120. A threaded rod 140 with both positive and negative threads is rotatably connected between the two fixed plates 120. The threaded rod 140 and the knob 130 are coaxially fixedly connected. Two clamping plates 300 are symmetrically located between the two fixed plates 120. Anti-slip pads 310 are installed on the side walls of the clamping plates 300. Threaded holes 320 are opened on the side walls of the clamping plates 300. The threaded rod 140 with both positive and negative threads rotates through the threaded holes 320. A guide rod 150 is installed between the two fixed plates 120. A guide hole 330 is provided on the side wall of the 300, and a guide rod 150 passes through the guide hole 330. During monitoring, the cell culture flask is first placed on top of the operating table 100 and between the two clamps 300. Rotating the knob 130 drives the threaded rod 140 to rotate. When the threaded rod 140 rotates, the screw structure pushes the two clamps 300 closer together and clamps the cell culture flask, fixing the cell culture flask in the middle position on top of the operating table 100. This can improve the stability of the operating table 100 during monitoring and prevent changes in the position of the operating table 100 from affecting the monitoring effect.

[0034] The base 400 is installed at the bottom of the operating table 100. The mounting plate 410 is installed on the symmetrical side wall of the base 400. The top of the mounting plate 410 has screw holes 420. By passing screws through the screw holes 420, the base 400 and the mounting plate 410 are fixed, which can further increase the stability during monitoring.

[0035] Although the present invention has been described above with reference to embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the features in the embodiments disclosed in this invention can be combined with each other in any way. The lack of an exhaustive description of these combinations in this specification is merely for the sake of brevity and resource conservation. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A patch assembly for visually monitoring environmental parameters within a cell culture flask, characterized in that, include: The operating table (100) has guide grooves (110) on its symmetrical sidewalls, and the guide grooves (110) extend to both sides of the operating table (100). A movable plate (200) is located on the side wall of the operating table (100). A monitoring device is installed on the side wall of the movable plate (200). A monitoring probe (210) is installed on the other side wall of the movable plate (200) above the operating table (100). The monitoring probe (210) is connected to the monitoring device. Multiple tension springs (220) are installed on the side wall of the movable plate (200) at positions corresponding to those on the operating table (100). The other end of each tension spring (220) is connected to a... The side wall of the operating table (100) is equipped with a side plate (230) on the symmetrical side wall of the moving plate (200). The side plate (230) is located on the side wall of the operating table (100). A ring of rubber blocks (240) is installed on the outer wall of the monitoring probe (210). There are multiple rubber blocks (240) evenly distributed on the outer wall of the monitoring probe (210). A guide plate (250) is installed on the inner wall of the side plate (230). The guide plate (250) is located inside the guide groove (110).

2. The cell culture flask internal environmental parameter visualization monitoring patch assembly according to claim 1, characterized in that, The top of the operating table (100) is symmetrically equipped with two fixing plates (120). A knob (130) is rotatably connected to the side wall of one of the fixing plates (120). A threaded rod (140) is rotatably connected between the two fixing plates (120). The threaded rod (140) is coaxially fixedly connected to the knob (130).

3. The cell culture flask internal environmental parameter visualization monitoring patch assembly according to claim 2, characterized in that, It also includes clamping plates (300), which are two and symmetrically located between the two fixing plates (120). Anti-slip pads (310) are installed on the side walls of the clamping plates (300), and threaded holes (320) are opened on the side walls of the clamping plates (300). The positive and negative threaded rods (140) rotate through the threaded holes (320).

4. The cell culture flask internal environmental parameter visualization monitoring patch assembly according to claim 3, characterized in that, A guide rod (150) is installed between the two fixing plates (120).

5. The cell culture flask internal environmental parameter visualization monitoring patch assembly according to claim 4, characterized in that, The side wall of the clamping plate (300) is provided with a guide hole (330), and the guide rod (150) passes through the guide hole (330).

6. The cell culture flask internal environmental parameter visualization monitoring patch assembly according to claim 5, characterized in that, It also includes a base (400), which is installed at the bottom of the operating table (100). The base (400) has mounting plates (410) installed on its symmetrical sidewalls, and the mounting plates (410) have screw holes (420) on their top.

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