Fast-dissolving softgel capsules containing ibuprofen

Abstract

The invention describes in certain embodiments a soft gel capsule including a filler material including ibuprofen or a pharmaceutically acceptable salt thereof, and a shell composition comprising a non-gelatinous bio-based polymer, the film dissolving completely in less than 30 minutes when subjected to dissolution with a USP Apparatus I at 75-200 rpm basket speed or a USP Apparatus II with paddle speed at 75 RPM in 900 ml of 50 mM phosphate buffer (pH 7.2) and deionized water at 37 degrees C.