MACROCYCLES AS MODULATORS OF TRANSMEMBRANE CONDUCTANCE REGULATOR IN CYSTIC FIBROSUS, PHARMACEUTICAL COMPOSITIONS THEREOF, THEIR USE IN THE TREATMENT OF CYSTIC FIBROSUS, AND METHOD FOR MANUFACTURING THEM

CY1125845T1Undetermined Publication Date: 2026-04-17VERTEX PHARMACEUTICALS INC
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Patent Information

Application Number
CY20231100087T
Authority / Receiving Office
CY · CY
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-02-15
Filing Date
2023-02-21
Publication Date
2026-04-17
Estimated Expiration
2043-02-21
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Abstract

Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Also disclosed are pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same.
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