Agent

Abstract

To provide an agent which does not utilize the toxicity of metal ions and exhibits one or two or more of high antibacterial, antifungal and antiviral properties in spite of a light color tone.SOLUTION: An agent comprising La (OH) 3, La2O2CO3, and ZnO, wherein a ratio (I (384) / I (560)) of a fluorescence emission intensity (I (560)) at a wave length of 365nm to a fluorescence emission intensity (I (384)) at a wave length of 560nm is 0.40 or more when the agent is irradiated with light having a wave length of 384nm and subjected to spectrofluorometric analysis, and the agent is selected from antibacterial agents, antifungal agents, and antiviral agents.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an agent, particularly to an agent that exhibits one or more of antibacterial, antifungal, and antiviral properties. [Background technology]

[0002] In recent years, from the viewpoint of hygiene, various products that have been subjected to antibacterial treatment have been distributed. There is a growing need for antibacterial, antifungal, antiviral, etc. properties not only for products that are directly used by consumers but also for, for example, exterior and interior walls of buildings, building materials, air filters, packings, etc.

[0003] Known compounds that exhibit antibacterial effects include phenols, organotin compounds, triazines, halogenated sulfonylpyridines, captans, organocuppers, chloronaphthalenes, and chlorophenylpyritazines (see Patent Document 1).

[0004] Silver ions, copper ions, zinc ions, etc. are known as ions that exhibit antibacterial effects. For example, metal powders such as silver, copper, zinc, etc., or alloys or compounds thereof are supported on a carrier, and trace amounts of these metal ions are eluted to utilize their toxicity. Patent Document 2 discloses a dispersion having deodorizing, antibacterial, and antifungal properties, in which a metal carboxylate formed from a carboxyl group-containing polymer and a metal compound is dispersed.

[0005] However, recently, pharmaceutical antibacterial agents, antifungal agents, etc., or antibacterial agents, antifungal agents, etc. that utilize the toxicity of metal ions have come to be viewed as problematic in terms of environmental pollution and safety.

[0006] Therefore, in recent years, ferrite compounds have been proposed as algae control agents that are less harmful to the environment and are highly safe.

[0007] For example, Patent Documents 3 and 4 disclose an anti-algae additive whose main component is orthoferrite containing a rare earth element selected from lanthanum (La), praseodymium (Pr), neodymium (Nd), and yttrium (Y), iron, and oxygen, an anti-algae paint using the additive, and an anti-algae product in which the paint is applied to the surface of a substrate, respectively.

[0008] Furthermore, Patent Document 5 discloses the antifungal effect of lanthanum ferrite, and Patent Document 6 discloses the antibacterial effect of lanthanum ferrite. [Prior art documents] [Patent documents]

[0009] [Patent Document 1] Japanese Patent Application Publication No. 17249 / 1983 [Patent Document 2] Japanese Patent Application Publication No. 2-288804 [Patent Document 3] Japanese Patent Application Laid-Open No. 2005-272320 [Patent Document 4] International Publication No. 2021 / 193644 [Patent Document 5] International Publication No. 2022 / 176743 [Patent Document 6] International Publication No. 2022 / 176742 Summary of the Invention [Problem to be solved by the invention]

[0010] The lanthanum ferrites disclosed in Patent Documents 5 and 6 exhibit excellent antifungal and antibacterial effects. However, lanthanum ferrite is dark brown in color. Therefore, materials containing lanthanum ferrite are brown in color, which imposes design restrictions and limits their applications.

[0011] The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an agent that does not utilize the toxicity of metal ions, has a light color tone, and yet exhibits one or more of high antibacterial, antifungal, and antiviral properties. [Means for solving the problem]

[0012] The present invention is as follows.

[0013] Aspect 1: An agent containing La(OH)3, La2O2CO3, and ZnO, When the agent is irradiated with light of a wavelength of 365 nm and analyzed with a spectrofluorometer, the ratio (I(560) / I(384)) of the fluorescence emission intensity at a wavelength of 384 nm (I(384)) to the fluorescence emission intensity at a wavelength of 560 nm (I(560)) is 0.40 or more; the agent is selected from antibacterial agents, antifungal agents, and antiviral agents; Agent. Aspect 2: The agent according to Aspect 1, wherein the ratio of lanthanum atoms to the total of lanthanum atoms and zinc atoms is 30 mol% or more and 95 mol% or less. Aspect 3: The agent according to Aspect 2, wherein the ratio of lanthanum atoms to the total of lanthanum atoms and zinc atoms is 50 mol % or more and 90 mol % or less. Aspect 4: The agent according to aspect 1, wherein the ratio (I(560) / I(384)) is 0.60 or greater. Aspect 5: The agent described in Aspect 1, wherein the ratio (I(560) / I(384)) is 0.80 or greater. Aspect 6: The agent according to any one of Aspects 1 to 5, which is an antibacterial agent. Aspect 7: An antibacterial article comprising the agent described in aspect 6. <<Aspect 8>> The antibacterial article according to Aspect 7, which is a printed matter, a card, a building material, fixtures, home appliances, stationery, information display equipment, toys, textile products, packaging supplies, sanitary products, filters, gaskets, or ceramics. Aspect 9: The agent according to any one of Aspects 1 to 5, which is an antifungal agent. Aspect 10: An antifungal article comprising the agent according to aspect 9. <<Embodiment 11>> The mold-resistant article according to embodiment 10, which is a printed matter, a card, a building material, fixtures, home appliances, stationery, information display equipment, toys, textile products, packaging supplies, sanitary products, filters, gaskets, or ceramics. Aspect 12: The agent according to any one of Aspects 1 to 5, which is an antiviral agent. Aspect 13: An antiviral article comprising the agent according to aspect 12. Aspect 14: The antiviral article according to Aspect 13, which is a printed matter, a card, a building material, fixtures, home appliances, stationery, information display equipment, a toy, a textile product, packaging supplies, sanitary products, a filter, a packing, or ceramics. Aspect 15: A method for producing the agent according to any one of aspects 1 to 5, comprising: Mixing lanthanum oxide and zinc oxide to obtain a lanthanum oxide-zinc oxide mixture; and The lanthanum oxide-zinc oxide mixture is calcined to obtain a calcined product. A manufacturing method comprising: Aspect 16: The method of aspect 15, wherein the firing temperature is 400°C or higher and 1,000°C or lower. Aspect 17: The method of aspect 15, further comprising treating the fired product with water. [Effects of the Invention]

[0014] According to the present invention, there is provided an agent that does not utilize the toxicity of metal ions, has a light color, and yet exhibits one or more of high antibacterial, antifungal, and antiviral properties. DETAILED DESCRIPTION OF THE INVENTION

[0015] The agent of the present invention is an agent containing La(OH)3, La2O2CO3, and ZnO, When the agent is irradiated with light of a wavelength of 365 nm and analyzed with a spectrofluorometer, the ratio (I(560) / I(384)) of the fluorescence emission intensity at a wavelength of 384 nm (I(384)) to the fluorescence emission intensity at a wavelength of 560 nm (I(560)) is 0.40 or more; the agent is selected from antibacterial agents, antifungal agents, and antiviral agents; It is a drug.

[0016] Lanthanum oxide is white, but its antibacterial, antifungal, and antiviral properties are insufficient. As mentioned above, lanthanum ferrite has high antibacterial and antifungal properties, but its dark brown color imposes design restrictions and limits its applications.

[0017] In response to these problems, the present inventors have discovered that a fired mixture of lanthanum oxide and zinc oxide is white and has high antibacterial, antifungal, and antiviral properties. The present invention was made based on this finding. The agent of the present invention is white under visible light, but emits yellow-green to orange fluorescence when irradiated with 365 nm ultraviolet light.

[0018] Agent The agent of the present invention comprises La(OH)3, La2O2CO3, and ZnO.

[0019] The La(OH)3, La2O2CO3, and ZnO contained in the agent of the present invention are not simply a mixture of these components, but it is believed that at least a portion of the ZnO (zinc oxide) is complexed with one or two lanthanum components selected from La(OH)3 and La2O2CO3. This is verified by the ultraviolet fluorescence properties of the agent of the present invention.

[0020] Specifically, when pure zinc oxide is irradiated with 365 nm light, it emits fluorescence with a wavelength of approximately 400 nm (purple). When this ZnO is combined with other oxides, its ultraviolet fluorescence properties may change. When irradiated with ultraviolet light with a wavelength of 365 nm, the agent of the present invention emits yellow-green to orange ultraviolet fluorescence.

[0021] Specifically, when the agent of the present invention is analyzed by a spectrofluorometer, in addition to a fluorescence emission peak at a wavelength of 384 nm, a fluorescence emission peak at a wavelength of 560 nm is observed. In this case, the ratio (I(560) / I(384)) of the fluorescence emission peak intensity at a wavelength of 384 nm (I(384)) to the fluorescence emission peak intensity at a wavelength of 560 nm (I(560)) is 0.40 or more. This ratio (I(560) / I(384)) may be 0.45 or more, 0.50 or more, 0.60 or more, 0.70 or more, 0.80 or more, 1.00 or more, 1.20 or more, or 1.50 or more, and may be 2.50 or less, 2.00 or less, 1.80 or less, or 1.50 or less.

[0022] In this specification, the term "ZnO" should be understood as a concept that encompasses not only pure zinc oxide but also zinc oxide at least partly composited with a La component.

[0023] In the agent of the present invention, the ratio of lanthanum atoms to the total of lanthanum atoms and zinc atoms may be 30 mol% or more, 40 mol% or more, 50 mol% or more, 60 mol% or more, or 65 mol% or more, and may be 95 mol% or less, 90 mol% or less, 85 mol% or less, 80 mol% or less, or 75 mol% or less, from the viewpoint of antibacterial activity.

[0024] In the agent of the present invention, a peak of La(OH)3, a peak of La2O2CO3, and a peak of ZnO may be observed in XRD measurement. Agents containing these crystalline phases are thought to exhibit one or more of high antibacterial, antifungal, and antiviral properties.

[0025] The XRD measurement may be carried out by the method described in the Examples below or by an appropriate method based thereon. In the obtained XRD chart, the peaks at the following scattering angles 2θ are attributed to La(OH)3, La2O2CO3, and ZnO, respectively. 2θ=27.958°(La(OH)3) 2θ=30.288°(La2O2CO3) 2θ=26.232°(ZnO)

[0026] The agent of the present invention may be in any form, such as powder, particulate, granular, etc., including La(OH)3, La2O2CO3, and ZnO. The agent may particularly be in powder form.

[0027] The particle size and specific surface area of ​​the agent of the present invention may be appropriately determined, for example, in the range of 0.01 μm or more and 10 μm or less, taking into account the balance between ensuring the probability of contact with bacteria, fungi, or viruses and ease of handling.

[0028] When the agent of the present invention is used as an antibacterial agent, antifungal agent, or antiviral agent, the 50% diameter (d50) in the volume cumulative distribution of the particle size distribution of the agent may be 0.1 μm or more and 2 μm or less.

[0029] The specific surface area of ​​the agent measured by the BET 1-point method in accordance with JIS Z8830 is 10m 2 / g or more 50m 2 / g or less.

[0030] <Optional ingredients> The agent of the present invention contains the above-mentioned La(OH)3, La2O2CO3, and ZnO, but may also contain other optional components.

[0031] Optional components that may be contained in the agent of the present invention include, for example, colorants, fillers, binders, dispersants, and other additives.

[0032] The proportion of the total mass of La(OH)3, La2O2CO3, and ZnO relative to the total mass of the agent of the present invention may be 50% by mass or more, 60% by mass or more, 70% by mass or more, 80% by mass or more, 85% by mass or more, 90% by mass or more, 95% by mass or more, 98% by mass or more, or 99% by mass or more, or the agent of the present invention may be composed only of La(OH)3, La2O2CO3, and ZnO without containing any optional components.

[0033] <<Manufacturing method of the agent>> According to another aspect of the present invention, there is provided a method for producing the agent.

[0034] The method for producing the agent of the present invention comprises the steps of: Mixing lanthanum oxide and zinc oxide to obtain a lanthanum oxide-zinc oxide mixture (lanthanum oxide-zinc oxide mixture forming step); and The lanthanum oxide and zinc oxide mixture is fired to obtain a fired product (firing step). Includes.

[0035] The method for producing the agent of the present invention may further include treating the baked product obtained above with water (water treatment step).

[0036] The lanthanum oxide-zinc oxide mixture forming step may be carried out by applying an appropriate stress to a mixture containing lanthanum oxide and zinc oxide in a predetermined ratio, followed by pulverizing and mixing.

[0037] Here, the "predetermined ratio" refers to a ratio that corresponds to the molar ratio of lanthanum atoms to zinc atoms in the desired agent.

[0038] The lanthanum oxide-zinc oxide mixture-forming process may be performed by dry or wet grinding. The stress applied to the mixture during the grinding and mixing process may be, for example, friction, shear, shear, or impact.

[0039] Examples of the method for applying the stress include wet pulverization in a ball mill. When wet pulverization is used, water, alcohol, or the like may be used as the liquid medium. After the mixture of lanthanum oxide and zinc oxide is pulverized and mixed by wet pulverization, the liquid medium may be removed by an appropriate method such as heat drying, if necessary, and then a firing step may be carried out.

[0040] The firing temperature and firing time in the firing step are not particularly limited, and can be set appropriately.

[0041] The calcination temperature may be, for example, 400° C. or higher, 500° C. or higher, 600° C., 700° C. or higher, 800° C. or higher, 900° C. or higher, or 1,000° C. or higher, and, for example, 1,300° C. or lower, 1,200° C. or lower, 1,100° C. or lower, or 1,000° C. The calcination temperature may in particular be 400° C. or higher and 1,000° C. or lower.

[0042] The firing time may be, for example, 1 hour or more, 2 hours or more, 3 hours or more, 4 hours or more, 6 hours or more, 8 hours or more, 12 hours or more, or 15 hours or more, and 72 hours or less, 48 ​​hours or less, 36 hours or less, 24 hours or less, 18 hours or less, or 15 hours or less.

[0043] The ambient atmosphere during firing may be an oxidizing atmosphere, for example, firing may be performed in air.

[0044] In the optional water treatment step, the calcined product obtained above may be brought into contact with water by any suitable method. The calcined product may be brought into contact with water by, for example, the following contact method. a method of adding liquid water to the fired product, bringing the fired product into contact with water, stirring the water as necessary, and then removing the water after contact; A method of supplying steam to the calcined product to bring it into contact with the calcined product, etc.

[0045] The contact of the baked product with liquid water may be carried out at a temperature of, for example, 0° C. or higher, 10° C. or higher, or 20° C. or higher, and 100° C. or lower, 60° C. or lower, or 40° C. or lower. This method may be repeated until the conductivity of the water after treatment becomes the same as that of tap water.

[0046] The contact of the calcined product with water vapor may be carried out at a temperature of 100°C or higher, 110°C or higher, or 120°C or higher, and 200°C or lower, 160°C or lower, or 140°C or lower.

[0047] In the water treatment step, contact with liquid water and contact with water vapor may be carried out in combination.

[0048] After the water treatment step, the treated product may be dried as desired before being used as the agent of the present invention. This drying may be carried out at a temperature of 100° C. or higher, 110° C. or higher, or 120° C. or higher and 200° C. or lower, 160° C. or lower, or 140° C. or lower, for 1 hour or longer, 2 hours or longer, 4 hours or longer, 6 hours or longer, or 8 hours or longer, and 72 hours or shorter, 48 hours or shorter, 24 hours or shorter, or 18 hours or shorter.

[0049] The reaction product obtained with or without the water treatment step may be mixed with any desired optional components as needed, and then pulverized as needed to adjust the particle size, and then used as the agent of the present invention.

[0050] <Application of the agent> The agent of the present invention exhibits one or more of high antibacterial, antifungal, and antiviral properties.Therefore, the agent of the present invention can be suitably used as an agent selected from antibacterial agents, antifungal agents, and antiviral agents.Specifically, the agent of the present invention can be used as, for example, an antibacterial agent, an antifungal agent, an antiviral agent, an antibacterial and antifungal agent, an antibacterial and antiviral agent, an antifungal and antiviral agent, or an antibacterial, antifungal, and antiviral agent.

[0051] The agent may be used, for example, in the form of a powder, or may be used in the form of a dispersion, paint, or the like.

[0052] The powdered agent can be used by being kneaded into the raw materials of desired antibacterial, antifungal, or antiviral products, and can also be used in the following applications: By placing the powdered agent in a suitable breathable bag and placing it in a room, toilet, etc., the surrounding area can be made into an antibacterial, antifungal, or antiviral environment. The powdered agent is added to water in air purifiers, water in cooling towers, aquaculture water, hydroponic water, etc. to suppress the growth of bacteria, mold, or viruses in the water, or to reduce the number of bacteria, mold, or viruses that have already grown. Mix the powdered agent into soil or sand (soil for plant cultivation, sandboxes in parks) to suppress the growth of bacteria, mold, or viruses in the soil or sand, or to reduce the number of bacteria, mold, or viruses that have already grown. etc.

[0053] The dispersion liquid contains, for example, the agent of the present invention and a solvent, and may contain other optional components. The solvent may be appropriately selected from water and organic solvents. The optional components may be components that are normally contained in dispersion liquids, such as dispersants, thickeners, pH adjusters, pigments, etc. The dispersion liquid containing the agent of the present invention may be added to the raw materials of a desired article, or may be applied to the surface of an appropriate article. Furthermore, by adding the dispersion liquid containing the agent of the present invention to a liquid (e.g., water in a fish tank, etc.), the liquid can be made into an antibacterial environment, an antifungal environment, or an antiviral environment.

[0054] The paint contains, for example, the agent of the present invention, a resin, and a solvent, and may contain other optional components. The solvent may be appropriately selected from water and organic solvents. The optional components may be components that are normally contained in paint, such as dispersants, thickeners, pH adjusters, pigments, etc. The paint containing the agent of the present invention may be used, for example, by applying it to the surface of an appropriate article.

[0055] 《Articles》 According to yet another aspect of the present invention, there is provided an article comprising the agent of the present invention. The article may be, for example, an antibacterial article, an antifungal article, or an antiviral article.

[0056] The agent of the present invention has low environmental pollution, excellent safety, and a light color tone. Therefore, articles containing the agent of the present invention are suitable for use in, for example, printed matter, cards, building materials, fixtures, home appliances, stationery, information display devices, toys, textile products, packaging supplies, sanitary products, filters, packing, ceramics, etc.

[0057] Examples of building materials include materials constituting the framework, exterior, and interior of a building, as well as sealants and joint materials. Fixtures are a concept that includes, for example, tools used in daily life, as well as store fixtures and office furniture. Examples of tools used in daily life include furniture and tableware. Examples of store fixtures include display stands, showcases, carts, wagons, stands, hangers, tables, and counters. Examples of office furniture include desks, chairs, whiteboards, cabinets, printers, and photocopiers. Examples of home appliances include refrigerators, washing machines, air conditioners, dishwashers, cooking appliances (microwave ovens, rice cookers, mixers, toasters, and the like), television sets, video players, personal computers (including peripherals), audio equipment, mobile phones, and switches. Examples of stationery include paper, notebooks, writing implements, drafting tools, rulers, and sealing paper. The information display device may be, for example, a poster, a sticker, a panel, a digital signage, etc. The toy may be, for example, a baby toy, a doll, a stuffed animal, a model, an acoustic toy, a practice toy, a puzzle, a ball, a vehicle, etc. The textile product may be, for example, a lab coat, a bed sheet, a curtain, clothing, a decorative item, etc. The nonwoven fabric product may be, for example, a gown (for medical care, nursing care, disasters, etc.), a storage bag, etc. The packaging product may be, for example, a packaging film, a packaging bag, etc. The hygiene product may be, for example, a mask, a diaper, a sanitary product, a bandage, a gauze, a bandage, etc. The filter may be, for example, an air filter, a water purification filter, etc. The packing may be, for example, a gasket, etc. The printed matter may be, for example, a banknote, a coupon, a security, etc. The ceramic may be, for example, a toilet, a sink, a tile, etc. The card may be, for example, a credit card, a bank card, an insurance card, a driver's license, etc. [Example]

[0058] Example 1 1. Synthesis of LaZn(agent) 0.45 mol parts of La2O3, 0.1 mol parts of ZnO, and water were charged into a ball mill using 10 mm diameter alumina balls as the grinding media, and the mixture was ground and mixed for 5 hours. The resulting ground product was dried at 300°C for 15 hours and then crushed in a rotary crusher. The resulting crushed product was fired at 700°C for 15 hours and then crushed in a hammer mill to obtain a crushed product.

[0059] Next, the crushed material was subjected to water treatment. In this water treatment, the crushed material obtained was placed in a washing tank, tap water was added and stirred, the treated water was removed by filtration, and then new tap water was added, followed by repeated stirring and filtration. The end point of the water treatment was the point at which the treated water and tap water had the same conductivity.

[0060] The crushed product after the water treatment was dried at 130°C for 15 hours and then crushed again with a hammer mill to obtain LaZn (agent) with a La:Zn = 90:10 (molar ratio). This LaZn was used as the agent in Example 1.

[0061] 2. XRD analysis of LaZn XRD analysis of the obtained LaZn was carried out under the following conditions. Measurement equipment: Rigaku Corporation, desktop X-ray diffraction equipment, model "MiniFlex600" Tube:CuK α (Wavelength 1.541862Å) Output: 40kV-15mA Measurement angle range (2θ): 10 to 80° Sampling interval: 0.01°

[0062] The resulting XRD chart was examined for the presence or absence of the following peaks. The crystal species to which the peaks belong is indicated in parentheses. 2θ=27.958°(La(OH)3) 2θ=30.288°(La2O2CO3) 2θ=36.232°(ZnO)

[0063] When the obtained XRD spectrum was examined for the presence or absence of peaks of La(OH)3, La2O2CO3, and ZnO, all three peaks were observed, confirming that the obtained LaZn contained a mixture of these three types of crystals.

[0064] 3. Specific surface area of ​​LaZn The specific surface area of ​​LaZn was measured by the BET single-point method in accordance with JIS Z8830 and found to be 26.9 m 2 / g.

[0065] 4. Antibacterial evaluation A 30 mL glass container with a lid was charged with 9.9 g of a diluted solution prepared by diluting Yakult Honsha's lactic acid bacteria drink "New Yakult" 10 times with purified water, and 0.1 g of LaZn was added. The container was then immediately shaken in an IntelliMixer for 24 hours. 30 minutes, 1 hour, and 24 hours after the start of shaking, 0.1 mL of the solution was sampled, and the ATP reduction rate (%) of the solution was measured. Specifically, the following method was used.

[0066] The collected solution was made to glow using an ATP measurement kit, "Lucifer AT100," manufactured by Kikkoman Biochemifa Corporation, and the amount of ATP luminescence was measured using a luminometer, "Lumitester C-110," manufactured by the same company.

[0067] Separately, a diluted solution without LaZn was also shaken in an Intellimixer for 24 hours in the same manner as above, and the solution was sampled 30 minutes, 1 hour, and 24 hours after the start of shaking. The ATP luminescence intensity of the sampled solution was measured, and the obtained values ​​were used as blank values ​​for each sampling time.

[0068] Then, the ATP luminescence level of the collected solution at each sampling time and the blank value were used to calculate the following formula: ATP reduction rate (%) = {(blank value - ATP luminescence amount of collected solution) / blank value} × 100 The ATP reduction rate (%) was calculated by the following.

[0069] 5. Hue evaluation A small amount of the obtained LaZn was placed on a glass petri dish, and the hue was visually examined under fluorescent lighting, and it was found to be white.

[0070] A small amount of the obtained LaZn was placed on a glass petri dish, the lights were turned off, and a black light (wavelength 365 nm) was shone on it. The presence or absence of fluorescence and the color of the fluorescence were visually examined, and yellow fluorescence was observed.

[0071] 6. Analysis of Fluorescence Wavelength The resulting LaZn was irradiated with light at a wavelength of 365 nm and the fluorescence intensity was measured using a Hitachi High-Tech Science F-7100 spectrofluorometer. The fluorescence emission peak intensity at a wavelength of 384 nm (I(384)) and the fluorescence emission peak intensity at a wavelength of 560 nm (I(560)) were measured, and the ratio of the two (I(560) / I(384)) was calculated, which was 0.702.

[0072] Examples 2 to 9 and Comparative Example 1 LaZn was synthesized in the same manner as in Example 1, except that the La:Zn ratio during the synthesis of LaZn and the firing temperature of the crushed material using the rotary crusher were changed as shown in Table 1, and this was evaluated as an agent for each example or comparative example.

[0073] Comparative Examples 2 to 6 A mixture of La2O3 and ZnO was obtained in the same manner as in Example 1, except that the La:Zn ratio was as shown in Table 1 and the crushed material was not fired using a rotary crusher, and this mixture was used as the agent for each comparative example.

[0074] Evaluation was carried out in the same manner as in Example 1, except that the above agents were used.

[0075] Comparative Example 7 Lanthanum iron oxide (LaFe) with a molar ratio of La:Fe=70:30 was obtained in the same manner as in Example 1, except that 0.35 molar parts of LaO and 0.3 molar parts of FeOOH were used instead of 0.45 molar parts of LaO and 0.1 molar parts of ZnO. This LaFe was used as the agent of Comparative Example 7 and evaluated in the same manner as in Example 1.

[0076] All the above results are shown in Table 1.

[0077] [Table 1]

[0078] The results in Table 1 reveal the following.

[0079] The agent of Comparative Example 1, which contained La but did not contain Zn, had low ATP reduction rates after 1 hour and 3 hours, and thus had poor initial antibacterial properties. The agents of Comparative Examples 2 to 5, which contained La and Zn but were not calcined and did not contain ZnO, and the agent of Comparative Example 6, which did not contain La, also had poor initial antibacterial properties. The fact that ZnO was not complexed in the agents of Comparative Examples 2 to 6 can be understood from the fact that these agents had small fluorescence intensity ratios (I(560) / I(384)) in spectrofluorophotometric analysis measured by irradiating these agents with light at a wavelength of 365 nm, and the color of the fluorescence was mainly purple around a wavelength of 384 nm, thereby maintaining the fluorescent properties of ZnO.

[0080] The color of the agents in Comparative Examples 1 to 6 was all white.

[0081] In contrast, the agents of Examples 1 to 9, which contained La and Zn and were calcined, showed excellent ATP reduction rates after 1 hour, 3 hours, and 24 hours, and the agent color was white.

[0082] In the formulations of Examples 1 to 9, the fluorescence intensity ratio (I(560) / I(384)) was large in spectrofluorophotometric analysis measured by irradiating with light of a wavelength of 365 nm, and in addition to purple fluorescence around a wavelength of 384 nm, yellow fluorescence around a wavelength of 560 nm was observed, which was significantly different from the fluorescent properties of pure zinc oxide. This verified that in the formulations of Examples 1 to 9, at least a portion of the ZnO was composited with the lanthanum component.

Claims

1. La(OH) ３ , La ２ O ２ CO ３ and ZnO, When the agent is irradiated with light of a wavelength of 365 nm and analyzed with a spectrofluorometer, the ratio (I(560) / I(384)) of the fluorescence emission intensity at a wavelength of 384 nm (I(384)) to the fluorescence emission intensity at a wavelength of 560 nm (I(560)) is 0.40 or more, the agent is selected from antibacterial agents, antifungal agents, and antiviral agents; Agent.

2. 2. The agent according to claim 1, wherein the ratio (mol %) of lanthanum atoms to the total of lanthanum atoms and zinc atoms is 30 mol % or more and 95 mol % or less.

3. The agent according to claim 2, wherein the ratio (mol %) of lanthanum atoms to the total of lanthanum atoms and zinc atoms is 50 mol % or more and 90 mol % or less.

4. The agent according to claim 1, wherein the ratio (I(560) / I(384)) is 0.60 or more.

5. The agent according to claim 1, wherein the ratio (I(560) / I(384)) is 0.80 or more.

6. The agent according to any one of claims 1 to 5, which is an antibacterial agent.

7. An antimicrobial article comprising the agent of claim 6.

8. The antibacterial article according to claim 7, which is a printed matter, a card, a building material, a fixture, a home appliance, stationery, a notice board, a toy, a textile product, a packaging product, a sanitary product, a filter, a packing, or ceramics.

9. The agent according to any one of claims 1 to 5, which is an antifungal agent.

10. An antifungal article comprising the agent according to claim 9.

11. The mold-proof article according to claim 10, which is a printed matter, a card, a building material, a fixture, a home appliance, stationery, a notice board, a toy, a textile product, a packaging product, a sanitary product, a filter, a packing, or ceramics.

12. The agent according to any one of claims 1 to 5, which is an antiviral agent.

13. An antiviral article comprising the agent of claim 12.

14. The antiviral article according to claim 13, which is a printed matter, a card, a building material, a fixture, a home appliance, stationery, an information display device, a toy, a textile product, a packaging product, a sanitary product, a filter, a packing, or ceramics.

15. A method for producing the agent according to any one of claims 1 to 5, comprising: Mixing lanthanum oxide and zinc oxide to obtain a lanthanum oxide-zinc oxide mixture; and Firing the lanthanum oxide / zinc oxide mixture to obtain a fired product. Including, Manufacturing method.

16. The method according to claim 15, wherein the firing temperature is 400°C or higher and 1,000°C or lower.

17. The method according to claim 15, further comprising treating the fired product with water.

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