Antigen response enhancer
An antigen response enhancer using Euglena and β-1,3-glucan increases naive T cells and enhances immune markers to improve immune function and counteract aging-related immune decline.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- KOBELCO ECO SOLUTIONS CO LTD
- Filing Date
- 2026-04-23
- Publication Date
- 2026-06-25
AI Technical Summary
As organisms age, the immune system declines due to an increase in senescent T cells and a decrease in naive T cells, leading to reduced antigen responsiveness, which compromises the immune defense mechanism.
An antigen response enhancer containing Euglena, paramylon, or β-1,3-glucan is developed to promote the increase in naive T cells, enhance CD28 expression, and increase other immune markers such as CD80, CD86, and HLA-DR in monocytes, thereby boosting the immune response.
The enhancer effectively increases the number and activity of naive T cells and regulatory T cells, enhances antigen presentation, and improves overall immune function, counteracting immunosenescence.
Smart Images

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Abstract
Citation Information
Patent Citations
Cosmetic or dermatological pharmaceutical composition containing Euglena extract
JP2008526954A