Specimen analyzer and specimen collection method
The specimen analyzer optimizes specimen handling through separate paths and mechanisms for biochemical and electrolyte detection, enhancing overall efficiency and detection capabilities.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- SHENZHEN NEW INDS BIOMEDICAL ENG CO LTD
- Filing Date
- 2025-01-27
- Publication Date
- 2026-06-19
AI Technical Summary
Conventional specimen analyzers with integrated electrolyte detection mechanisms face efficiency issues in supplying specimens to reaction disks, affecting detection efficiency.
A specimen analyzer design with separate rails and addition mechanisms for biochemical and electrolyte detection, featuring independent sample and reagent transfer paths, and a sample rack transfer mechanism to optimize specimen handling within a limited space.
Enhances specimen transfer efficiency for both biochemical and electrolyte detection without interference, allowing simultaneous and efficient performance of both types of analyses.
Smart Images

Figure 0007876651000001 
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Figure 0007876651000003
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of analytical instruments, and particularly to an analytical apparatus for specimens and a method for collecting specimens.
Background Art
[0002] Biochemical analyzers, immunoassays, and cell analyzers all belong to specimen analyzers, which are instruments for performing qualitative and quantitative analysis on specimens.
[0003] With the diversification of functions, in addition to performing liver function tests, kidney function tests, fasting blood glucose tests, uric acid tests, etc. on reaction disks, many specimen analyzers also integrate an electrolyte detection mechanism for electrolyte detection.
[0004] Among conventional specimen analyzers, a specimen analyzer integrated with an electrolyte detection mechanism needs to also serve as a supply of specimens to the electrolyte detection mechanism, so the efficiency of supplying specimens to the reaction disk decreases, affecting the detection efficiency of the reaction disk.
Summary of the Invention
Problems to be Solved by the Invention
[0005] The present invention provides a specimen analyzer and a specimen collection method that can solve, or at least partially alleviate or reduce, the above problems.
Means for Solving the Problems
[0006] The specimen analyzer according to one aspect of the present application includes a first rail, a second rail, a reaction disk on which reaction vessels are placed, an electrolyte detection mechanism on which detection vessels are placed, a first specimen addition mechanism for transferring a specimen located on the first rail into the reaction vessel, and a second specimen addition mechanism for transferring a specimen located on the second rail into the detection vessel.
[0007] Furthermore, the reaction disk has a horizontal symmetry line and a vertical symmetry line, The electrolyte detection mechanism, the first rotation center of the second sample addition mechanism, and the second rail are provided between the first rail and the horizontal symmetry line and are located on the same side of the vertical symmetry line.
[0008] Furthermore, when the second sample addition mechanism transfers the sample on the second rail to the detection container, the second sample rack is placed on the second rail, and the second sample addition mechanism moves into a different sample container supported on the second sample rack to collect the sample.
[0009] Furthermore, the second sample addition mechanism includes a folding arm and a sampling needle, the folding arm moves the sampling needle into different sample containers supported by the second sample rack, and collects a sample with the sampling needle, or The second sample addition mechanism includes an extendable arm and a sampling needle, the extendable arm moves the sampling needle into different sample containers supported by the second sample rack, and the sampling needle collects the sample.
[0010] Furthermore, the first sample addition mechanism includes a first sample addition arm and a second sample addition arm, which are independent of each other. The first sample-adding arm rotates around the second rotation center, and the second sample-adding arm rotates around the third rotation center. The first and second rotation centers are provided on opposite sides of the vertical symmetry line, The third center of rotation and the second center of rotation are located on the same side of the vertical symmetry line, The second pivot center is located between the first pivot center and the third pivot center.
[0011] Furthermore, the reaction disc includes an outer reaction tray and an inner reaction tray provided inside the outer reaction tray. The first sample addition arm is used to transfer the sample located on the first rail into the reaction vessel placed on the reaction inner tray. The second sample addition arm is used to transfer the sample located on the first rail into the reaction vessel placed on the reaction outer tray.
[0012] Here, both the first sample-adding arm and the second sample-adding arm sample at a common sampling point on the first rail. The first sample rack moves along the first rail so that each of the sample containers in the first sample rack sequentially reaches the common sampling point.
[0013] Furthermore, the reaction disk includes a first reagent dispensing position and a second reagent dispensing position. The aforementioned sample analyzer further comprises a reagent container storage mechanism, The reagent container storage mechanism is for placing the reagent container and is located outside the reaction disk, and is located on the side away from the electrolyte detection mechanism along the horizontal line of symmetry. The reagent container storage mechanism includes a first reagent aspiration position and a second reagent aspiration position. The sample analyzer further comprises a reagent injection mechanism, the reagent injection mechanism further includes an independently controlled first reagent needle and a second reagent needle. The first reagent needle is used to aspirate a reagent from the reagent container located at the first reagent aspiration position, and to transfer and discharge the reagent along a first straight line into the reaction vessel located at the first reagent discharge position. The second reagent needle is used to aspirate a reagent from the reagent container located at the second reagent aspiration position, and to transfer and discharge the reagent along the second straight line into the reaction vessel located at the second reagent discharge position.
[0014] Furthermore, the samples located on the first rail and the samples located on the second rail enter the sample analyzer via the first rail.
[0015] Here, the sample transferred only to the reaction vessel is accommodated in the sample container carried on the first sample rack. At least the sample transferred into the detection container is accommodated in the sample container carried on the second sample rack. The sample analyzer further includes a sample rack transfer mechanism, and the second sample rack is transferred from the first rail to the second rail through the sample rack transfer mechanism.
[0016] Furthermore, it further includes a third rail. The first rail, the second rail, and the third rail are parallel to each other. The first sample rack and the second sample rack are separated from the sample analyzer through the third rail. The sample rack transfer mechanism is further used to transfer the first sample rack on the first rail or the second sample rack on the second rail to the third rail.
[0017] Here, the sample rack transfer mechanism includes a relay rail and a first driving device. The first driving device drives the relay rail so that the relay rail is connected to the first discharge end on the first rail, and the relay rail is respectively connected to the input / output end of the second rail or the third supply end of the third rail. Alternatively, the sample rack transfer mechanism includes a second driving device and a gripper. Under the driving of the second driving device, the gripper transfers the second sample rack on the first rail to the second rail, and transfers the second sample rack on the second rail and the first sample rack on the second rail to the third rail.
[0018] Furthermore, the first rail is used to transport the first sample rack and the second sample rack. The first sample rack places the sample that requires biochemical testing. The second specimen rack is for placing specimens that require electrolyte detection, or the second specimen rack is for placing specimens that require electrolyte detection and specimens that require biochemical tests. The second specimen rack is transferred from the first rail to the second rail and places specimens that require electrolyte detection. The reaction tray is used to perform biochemical tests on the specimens in the reaction vessel.
[0019] In another aspect, the present invention further provides a method for collecting specimens of a specimen analyzer. The specimen collection method is as follows: In the first sampling zone, the first specimen adding mechanism transfers the specimen in the specimen container carried on the first specimen rack to the reaction container placed on the reaction disk. In the second sampling zone, the second specimen adding mechanism transfers the specimen in the specimen container carried on the second specimen rack to the detection container placed on the electrolyte detection mechanism. The second specimen rack passes through the first sampling zone in the process of being transferred to the second sampling zone.
[0020] Furthermore, the first sampling zone is located on the first rail, the second sampling zone is located on the second rail, The second rail and the first rail are parallel to each other. The second specimen rack is transferred from the first rail to the specimen rack transfer mechanism and then from the specimen rack transfer mechanism to the second rail.
[0021] Furthermore, when the second specimen rack reaches the first sampling zone, the first specimen adding mechanism transfers the specimen in the specimen container carried on the second specimen rack to the reaction container. When the second specimen rack reaches the second sampling zone, the second specimen adding mechanism transfers the specimen in the specimen container carried on the second specimen rack to the detection container.
[0022] Here, after the first sample addition mechanism transfers the sample from the sample container supported on the second sample rack to the reaction vessel, the second sample rack moves from the first sampling zone to the first discharge end of the first rail, and then moves from the first discharge end to the sample rack transfer mechanism. The specimen rack transfer mechanism moves the second specimen rack to the inlet / outlet end of the second rail, The second sample rack extends from the input / output end to the second sampling zone, and the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container placed on the electrolyte detection mechanism. After the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container, the second sample rack moves from the second sampling zone to the input / output end, and from the input / output end to the sample rack transfer mechanism.
[0023] Furthermore, in the process of transferring the sample from the sample container supported on the second sample rack to the detection container, the second sample addition mechanism can move into a different sample container supported on the second sample rack and collect the sample.
[0024] Furthermore, in the process by which the first sample addition mechanism transfers samples from the sample containers supported on the first sample rack to the reaction vessel, the sample containers supported on the first sample rack sequentially pass through common sampling points, and the first sample addition mechanism transfers samples from the sample containers located at the common sampling points to the reaction vessel.
[0025] Here, the first sample addition mechanism includes a first sample addition arm and a second sample addition arm, which are independent of each other. The reaction disc includes an outer reaction tray and an inner reaction tray provided inside the outer reaction tray. In the process by which the first sample addition mechanism transfers a sample from a sample container supported on the first sample rack to a reaction vessel supported on the reaction disk, the first sample addition arm aspirates the first sample from one of the sample containers located at the common sampling point and transfers the first sample into the reaction vessel placed on the reaction inner tray, and in the process by which the first sample is transferred by the first sample addition arm to the reaction vessel placed on the reaction inner tray, the second sample addition arm aspirates the first sample from one of the sample containers located at the common sampling point and transfers the first sample into the reaction vessel placed on the reaction outer tray, Alternatively, during the process in which the first sample is transferred by the first sample addition arm to the reaction vessel placed on the reaction inner tray, the second sample addition arm aspirates a second sample from another sample container located at the common sampling point and transfers the second sample into the reaction vessel placed on the reaction outer tray. [Effects of the Invention]
[0026] In this invention, the first sample addition mechanism transfers the sample from the first rail into the reaction vessel placed on the reaction disk, and the second sample addition mechanism transfers the sample from the second rail into the detection container supported by the electrolyte detection mechanism, thereby efficiently achieving both the transfer of the sample necessary for detection to the reaction vessel placed on the reaction disk and the transfer of the sample necessary for electrolyte detection without affecting the transfer of the sample necessary for detection to the reaction vessel placed on the reaction disk. [Brief explanation of the drawing]
[0027] The drawings described herein are used to provide a further understanding of the present application and constitute part of the present application. Exemplary embodiments and descriptions thereof are used to interpret the present application and do not constitute an unreasonable limitation thereto. In the drawings, [Figure 1] This is a schematic diagram of the sample analyzer in one embodiment disclosed in this application. [Figure 2] This is a partial diagram of the first reagent injection mechanism disclosed in this application. [Figure 3] This is a flowchart of the sample transport method in one embodiment disclosed in this application. [Figure 4] This is a flowchart of the sample transport method in another embodiment disclosed in this application. [Figure 5] This is a flowchart of the sample collection method in one embodiment disclosed in this application. [Modes for carrying out the invention]
[0028] Furthermore, the embodiments and features described herein can be combined with each other, as long as they do not contradict each other. The present invention will now be described in detail with reference to the drawings, in accordance with the embodiments.
[0029] The terms used herein are used solely to describe specific embodiments and are not intended to limit the exemplary embodiments provided herein. As used herein, the singular form is also intended to include the plural form unless the context specifically indicates otherwise. Furthermore, when the terms “include” and / or “contain” are used herein, it should be understood that they also indicate the presence of features, steps, actions, devices, components, and / or combinations thereof.
[0030] The relative arrangements, numerical expressions, and numerical values of the components and steps described in these embodiments do not limit the scope of this application unless otherwise specified. It should be understood that, for ease of explanation, the dimensions of the parts shown in the drawings are not based on actual proportional relationships. While technologies, methods, and apparatus known to the general articulate to the art may not be discussed in detail, where appropriate, such technologies, methods, and apparatus should be considered part of the patented specification. In all examples shown and discussed herein, any specific values should be interpreted as illustrative only, not as limitations. Therefore, other examples of the exemplary embodiments may have different values. Similar reference numerals and letters represent similar items in subsequent drawings; therefore, once an item is defined in a drawing, it does not need to be discussed further in subsequent drawings.
[0031] As shown in Figures 1 and 2, the sample analyzer 100 provided by the present invention includes a first rail 21, a second rail 22, a reaction disk 10, an electrolyte detection mechanism 30, a first sample addition mechanism, and a second sample addition mechanism.
[0032] The reaction disk 10 is located on a stage and has reaction vessels on which specimens requiring biochemical testing are placed.
[0033] The electrolyte detection mechanism 30 is mounted on the aforementioned stage and located outside the reaction disk 10. A detection container for containing a sample requiring electrolyte detection is placed on the electrolyte detection mechanism 30.
[0034] The first sample addition mechanism is installed on the aforementioned stage and located outside the reaction disk 10, and transfers the sample located on the first rail 21 into the aforementioned reaction vessel, and performs biochemical testing on the sample.
[0035] The second sample addition mechanism is installed on the aforementioned stage and located outside the reaction disk 10, and transfers the sample located on the second rail 22 into the aforementioned detection container, and performs electrolyte detection on the sample.
[0036] In this embodiment, the second sample addition mechanism described above transfers the sample from the second rail 22 to the detection container on which the electrolyte detection mechanism 30 is placed, while the first sample addition mechanism described above transfers the sample from the first rail 21 to the reaction vessel on which the reaction disk 10 is placed, independently. By performing the transfer of the sample to the detection container and the transfer of the sample to the reaction vessel independently in this way, it is possible to efficiently transfer the samples necessary for electrolyte detection without affecting the dispensing of the sample into the reaction vessel placed on the reaction disk 10.
[0037] Furthermore, the reaction disk 10 is configured to form an ejection position. The aforementioned first sample addition mechanism draws a sample from the first rail 21 and transfers the sample into the reaction vessel located at the aforementioned ejection position for ejection.
[0038] Furthermore, the reaction disk 10 can accommodate multiple reaction vessels. The reaction disk 10 can be rotated to move the multiple reaction vessels along a third rotation path. As the multiple reaction vessels rotate along the third rotation path, they sequentially pass through the discharge positions.
[0039] Furthermore, the reaction disk 10 has a horizontal symmetry line 102 and a vertical symmetry line 104 passing through the third rotation center 15. The horizontal symmetry line 102 and the vertical symmetry line 104 divide the reaction disk 10 into the first quadrant, the second quadrant, the third quadrant, and the fourth quadrant.
[0040] The electrolyte detection mechanism 30, the first rotation center 421 of the aforementioned second sample addition mechanism, and the second rail 22 are provided between the first rail 21 and the horizontal symmetry line 102, and are located on the same side of the vertical symmetry line 104. This allows the electrolyte module, including the electrolyte detection mechanism 30, the second sample addition mechanism, and the second rail 22, to be integrated within the limited space of the aforementioned stage. Therefore, the sample analyzer 100 can efficiently perform biochemical analysis and efficiently detect electrolytes simultaneously within a limited space.
[0041] In one embodiment, the aforementioned electrolyte module is located outside the reaction disk 10 and within the first quadrant.
[0042] In another embodiment, the aforementioned electrolyte module is located outside the reaction disk 10 and within the second quadrant.
[0043] In other embodiments, the aforementioned electrolyte module may be located outside the reaction disk 10 and within the third quadrant, or it may be located outside the reaction disk 10 and within the fourth quadrant.
[0044] Furthermore, only the samples transferred to the aforementioned reaction vessel are placed in the sample containers carried on the first sample rack. That is, after the first sample loading mechanism has completed the collection of samples from the sample containers carried on the first sample rack, the first sample rack is directly retrieved.
[0045] At least the samples transferred into the detection container are placed in the sample containers supported on the second sample rack. That is, when the second sample addition mechanism finishes collecting samples from the sample containers supported on the second sample rack, the second sample rack is retrieved.
[0046] In one embodiment, an electrolyte sampling point is formed at the intersection of the sampling needle of the second sample addition mechanism and the second rail 22. The sampling needle of the second sample addition mechanism samples from the sample container located at the aforementioned electrolyte sampling point.
[0047] When the second sample addition mechanism transfers the sample from the second rail 22 to the aforementioned detection container, that is, when the second sample addition mechanism transfers the sample from the sample containers supported on the second sample rack to the aforementioned detection container, the second rail 22 moves so that each sample container supported on the second sample rack passes sequentially through the aforementioned electrolyte sampling point, thereby facilitating sampling by the sampling needle of the second sample addition mechanism.
[0048] Specifically, the sampling needle of the aforementioned second sample addition mechanism rotates around the first rotation center 421 between the aforementioned electrolyte sampling point and the aforementioned detection container to transfer and inject the sample.
[0049] In another embodiment, because the available space for installing the second rail 22 is limited, the second sample rack on the second rail 22 cannot move along the second rail 22 to sequentially pass each sample container it carries through to the aforementioned electrolyte sampling point.
[0050] Therefore, after the second sample rack is transferred to the second rail 22, the second sample rack is placed on the second rail 22, and the aforementioned second sample addition mechanism moves into the different sample containers supported by the second sample rack, allowing for sample collection.
[0051] Specifically, the sampling needle of the aforementioned second sample addition mechanism can move into different sample containers supported by the second sample rack, which is placed on the second rail 22, and perform sampling.
[0052] In one embodiment, the aforementioned second sample addition mechanism includes a folding arm and a sampling needle. The folding arm can move the aforementioned sampling needle into different sample containers supported by the second sample rack, and sample can be collected with the aforementioned sampling needle.
[0053] Specifically, the aforementioned folding arm includes a first sub-folding arm 422 and a second sub-folding arm 423. The first sub-folding arm 422 is rotatably mounted at one end around a first pivot center 421, and its other end is connected to one end of the second sub-folding arm 423. The second sub-folding arm 423 is rotatable relative to the first sub-folding arm 422. The other end of the second sub-folding arm 423 is connected to a sampling needle.
[0054] By positioning the sampling needle on a folding arm, the sampling needle can sample within the second sampling zone on the second rail 22. Since the second sampling zone can accommodate at least one second sample rack, the sampling needle can sample from any sample container in the second sample rack placed in the second sampling zone.
[0055] In another embodiment, the aforementioned second sample addition mechanism includes an extendable arm and a sampling needle. The extendable arm can move the sampling needle into different sample containers supported by the second sample rack, thereby allowing the sampling needle to collect samples.
[0056] Specifically, the aforementioned telescopic arm includes at least a first sub-telescopic arm and a second sub-telescopic arm. The first sub-folding arm is rotatably mounted at one end around a first pivot center 421, and its other end is connected to one end of the second sub-telescopic arm. The second sub-telescopic arm is extendable relative to the first sub-telescopic arm. The other end of the second sub-telescopic arm is connected to a sampling needle.
[0057] By mounting the sampling needle on the aforementioned telescopic arm, the sampling needle can sample within the second sampling zone on the second rail 22. Since the second sampling zone can accommodate at least one second sample rack, the sampling needle can sample from any of the sample containers in the second sample rack placed in the second sampling zone.
[0058] Furthermore, the electrolyte detection mechanism 30 includes at least one sample injection position for injecting an electrolyte detection sample.
[0059] In one particular embodiment, the electrolyte detection mechanism 30 includes a first sample injection position 31 and a second sample injection position 32. The aforementioned second sample addition mechanism can transfer the aforementioned sample to the aforementioned detection container at the first sample injection position 31 or the second sample injection position 32.
[0060] Furthermore, the aforementioned first sample addition mechanism comprises a first sample addition arm 411 and a second sample addition arm 412, which are independent of each other. The first sample addition arm 411 and the second sample addition arm 412 each transfer the sample from the sample container supported by the first sample rack on the first rail 21 into the reaction vessel on which the reaction disk 10 is placed.
[0061] In one embodiment, the sampling needle in the first sample-adding arm 411 and the sampling needle in the second sample-adding arm 412 move along a straight line to transport the sample.
[0062] In another embodiment, the first sample-adding arm 411 rotates around a second pivot center 413, and the second sample-adding arm 412 rotates around a third pivot center 414.
[0063] Furthermore, in one embodiment, the reaction disk 10 has a single-ring structure and has a plurality of third mounting positions formed along the aforementioned third rotation path. Each third mounting position can accommodate one reaction vessel. The reaction disk 10 is rotatable and moves the plurality of third mounting positions to sequentially pass through the aforementioned discharge positions.
[0064] In another embodiment, the reaction disk 10 has a double-ring structure, namely, it includes an outer reaction tray 11 and an inner reaction tray 12 located inside the outer reaction tray 11.
[0065] The sampling needle of the first sample addition arm 411 is used to transfer the sample located on the first rail 21 into the reaction vessel placed on the reaction inner tray 12. The sampling needle of the second sample addition arm 412 is used to transfer the sample located on the first rail 21 into the reaction vessel placed on the reaction outer tray 11.
[0066] Specifically, the reaction inner tray 12 is configured to form an inner sample discharge position 121, and the reaction outer tray 11 is configured to form an outer sample discharge position 111.
[0067] The reaction inner tray 12 has a plurality of third internal mounting positions 122 formed along a third internal rotation path. Each third internal mounting position 122 can accommodate one of the reaction vessels.
[0068] The reaction inner tray 12 can rotate so that multiple third internal mounting positions 122 move in conjunction to sequentially pass through the internal sample dispensing position 121.
[0069] The reaction outer tray 11 has multiple third external mounting positions 112 formed along the third external rotation path. Each third external mounting position 112 can accommodate one reaction vessel.
[0070] The reaction outer tray 11 can rotate so that multiple third external mounting positions 112 move in conjunction to sequentially pass through the external sample dispensing position 111.
[0071] Furthermore, both the first sample-adding arm 411 and the second sample-adding arm 412 sample at the common sampling point 211 on the first rail 21. The first sample rack moves along the first rail 21 so that each sample container in the first sample rack sequentially reaches the common sampling point 211.
[0072] Specifically, the motion trajectories of the sampling needle of the first sample-adding arm 411 and the motion trajectory of the sampling needle of the second sample-adding arm 412 intersect at the first rail 21 and the common sampling point 211, respectively, so that both the sampling needle of the first sample-adding arm 411 and the sampling needle of the second sample-adding arm 412 sample at the common sampling point 211.
[0073] By providing the aforementioned common sampling point 211, each sample container carried on the first sample rack will be sampled by the sampling needle of the first sampling arm 411 or the sampling needle of the second sampling arm 412 as it sequentially passes through the common sampling point 211. This efficiently shortens the movement path of the first sample rack on the first rail 21, reduces the difficulty of controlling the movement of the first sample rack on the first rail 21, and improves the transport efficiency and sampling efficiency of the sample containers.
[0074] In addition, by providing the aforementioned common sampling point 211, the motion path of the sampling needle of the first sampling arm 411 and the motion path of the sampling needle of the second sampling arm 412 can be calibrated using the common sampling point 211 as a reference point, and the calibration efficiency is high. Furthermore, by bringing the first sampling arm 411 and the second sampling arm 412 closer together, the space occupied by the first sampling arm 411 and the second sampling arm 412 can be reduced, thereby increasing the integration density of the first sampling arm 411 and the second sampling arm 412.
[0075] In the single-ring reaction disk 10, the sampling needle of the first sample addition arm 411 and the sampling needle of the second sample addition arm 412 each transfer the sample collected from the common sampling point 211 into the reaction vessel placed on the reaction disk 10.
[0076] In the double-ring reaction disk 10, the sampling needle of the first sample addition arm 411 can transfer the sample collected from the common sampling point 211 into the reaction vessel placed on the inner reaction tray 12 or the outer reaction tray 11. The sampling needle of the second sample addition arm 412 can also transfer the sample collected from the common sampling point 211 into the reaction vessel placed on the inner reaction tray 12 or the outer reaction tray 11.
[0077] Preferably, the sampling needle of the first sample addition arm 411 is used to transfer the sample taken from the common sampling point 211 into the reaction vessel placed on the reaction inner tray 12, and the sampling needle of the second sample addition arm 412 is used to transfer the sample taken from the common sampling point 211 into the reaction vessel placed on the reaction outer tray 11.
[0078] Furthermore, the first rotation center 421 and the second rotation center 413 are located on opposite sides of the vertical symmetry line 104, respectively. The third rotation center 414 and the second rotation center 413 are located on the same side of the vertical symmetry line 104. This ensures that the first and second sample addition mechanisms are positioned on opposite sides of the vertical symmetry line 104, preventing interference between them when injecting biochemical test samples and electrolyte detection samples, respectively.
[0079] Furthermore, the second rotation center 413 is located between the first rotation center 421 and the third rotation center 414. In one specific embodiment, the sampling needle of the first sample addition arm 411 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction inner tray 12, and the sampling needle of the second sample addition arm 412 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction outer tray 11.
[0080] In one embodiment, the sample located on the first rail 21 and the sample located on the second rail 22 enter the sample analyzer 100 via the aforementioned first rail 21.
[0081] Furthermore, the sample analyzer 100 is further equipped with a sample rack transfer mechanism 23. The second sample rack is transferred from the first rail 21 to the second rail 22 via the sample rack transfer mechanism 23 to facilitate sampling by the second sample addition mechanism on the second rail 22. This avoids the second sample addition mechanism sampling on the first rail 21 and also enables independent sampling by the first and second sample addition mechanisms, allowing the sample analyzer 100 to efficiently perform biochemical sampling while simultaneously performing electrolyte detection sampling without reducing speed.
[0082] Furthermore, the sample analyzer 100 further includes a third rail 24 used for retrieving the sample racks. After the first and second sample racks have completed their corresponding sampling, the sample rack transfer mechanism 23 transfers the first and second sample racks to the aforementioned third rail 24. The first and second sample racks then move away from the sample analyzer 100 via the third rail 24.
[0083] In one embodiment, the first rail 21, the second rail 22, and the third rail 24 are parallel to each other. The specimen rack transfer mechanism 23 can also be used to transfer the first specimen rack on the first rail 21, or the second specimen rack on the second rail 22, to the third rail 24.
[0084] Specifically, the specimen rack transfer mechanism 23 can transfer specimen racks between the first rail 21 and the second rail 22, between the first rail 21 and the third rail 24, and between the second rail 22 and the third rail 24.
[0085] Furthermore, in one embodiment, the specimen rack transfer mechanism 23 includes a relay rail 231 and a first drive unit 232. The first drive unit 232 can be driven so that the relay rail 231 is connected to a first discharge end 213 of the first rail 21 in order to facilitate the transfer of a first specimen rack or a second specimen rack on the first rail 21 to the relay rail 231.
[0086] The first drive unit 232 is also used to drive the relay rail 231 so that it connects to the input / output end 221 of the second rail 22, in order to facilitate the transfer of the second sample rack on the relay rail 231 to the second rail 22 or the transfer of the second sample rack on the second rail 22 to the relay rail 231.
[0087] The first drive unit 232 can further drive the relay rail 231 so that it connects to the third supply end 241 of the third rail 24, thereby transferring the first or second sample rack on the relay rail 231 to the third rail 24, and facilitating the first or second sample rack to move away from the sample analyzer 100 by the third rail 24.
[0088] In another embodiment, the sample rack transfer mechanism 23 includes a second drive unit and a gripper. Under the drive of the aforementioned second drive unit, the aforementioned gripper transfers the second sample rack on the first rail 21 to the second rail 22, facilitating the second sample addition mechanism to collect the sample necessary for electrolyte detection from the second sample rack.
[0089] Under the operation of the aforementioned second drive device, the aforementioned gripper transfers the first sample rack on the first rail 21 to the third rail 24, and also transfers the second sample rack on the second rail 22 to the third rail 24, thereby facilitating the removal of the first or second sample rack from the sample analyzer 100 by the third rail 24.
[0090] In some more specific embodiments, the second drive device may be a drive mechanism, such as a three-dimensional mobile module or a robotic arm, for driving the aforementioned gripper to transport the specimen rack between the first rail 21, the second rail 22, and the third rail 24.
[0091] Furthermore, in one embodiment, the first rail 21 can be used to transport the first sample rack and the second sample rack. Here, the sample containers carried on the first sample rack contain samples that require biochemical testing.
[0092] After the first sample addition mechanism completes the collection of samples necessary for biochemical testing in the sample containers supported on the first sample rack, the first sample rack moves along the first rail 21 toward the sample rack transfer mechanism 23 and is transferred to the relay rail 231. Subsequently, the first drive unit 232 drives the relay rail 231 to connect it to the third supply end 241 of the third rail 24, thereby transferring the first sample rack to the third rail 24. Finally, the aforementioned first sample rack moves along the third rail 24 away from the sample analyzer 100.
[0093] Alternatively, after the first sample addition mechanism collects the sample necessary for biochemical testing in the sample container supported on the first sample rack, the aforementioned second drive device drives the aforementioned gripper to clamp the first sample frame and transfer it to the third rail 24.
[0094] Furthermore, the aforementioned second sample rack is transported from the first rail 21 to the second rail 22 and is used to place samples that require electrolyte detection.
[0095] In one embodiment, the sample containers supported on the aforementioned second sample rack contain samples requiring electrolyte detection.
[0096] Specifically, after the second sample rack enters the sample analyzer 100 from the first rail 21, the second sample rack moves along the first rail 21 to the first discharge end 213 of the first rail 21, and then moves from the first discharge end 213 to the relay rail 231.
[0097] Subsequently, the first drive unit 232 drives the relay rail 231 on which the second sample rack is placed so that it connects to the input / output end 221 of the second rail 22, and after the connection is made, it transfers the second sample rack to the second rail 22, facilitating the second sample addition mechanism to collect the sample necessary for electrolyte detection.
[0098] Once the second sample addition mechanism has finished collecting samples requiring electrolyte detection from the second sample rack, the second sample rack moves to the inlet / outlet end 221 of the second rail 22 and is transferred to the relay rail 231.
[0099] Next, the first drive unit 232 drives the relay rail 231 so that it connects to the third supply end 241 of the third rail 24, and transfers the second sample rack to the third rail 24. Finally, the aforementioned second sample rack moves away from the sample analyzer 100 via the third rail 24.
[0100] Alternatively, after the second sample rack enters the sample analyzer 100 from the first rail 21, the aforementioned second drive device drives the gripper to grasp the second sample rack and move it to the second rail 22. Then, the second sample addition mechanism collects the sample necessary for electrolyte detection from the sample container carried on the second sample rack.
[0101] Once the aforementioned second sample addition mechanism has finished collecting the sample requiring electrolyte detection from the second sample rack, the second drive unit drives the second sample rack again to grip it with the aforementioned gripper and move it to the third rail 24. Subsequently, the aforementioned second sample rack moves away from the sample analyzer 100 via the third rail 24.
[0102] In another embodiment, the sample containers supported on the second sample rack contain samples requiring electrolyte detection and samples requiring biochemical testing. The samples contained in the sample containers supported on the second sample rack are sampled by the sampling needle of the first sampling arm 411 or by the sampling needle of the second sampling arm 412 as they pass the common sampling point 211 on the first rail 21, and then move to the second rail 22 where they are sampled by the sampling needle of the second sample addition mechanism. As a result, the sample containers supported on the second sample rack efficiently combine sampling by the first sample addition mechanism and sampling by the second sample addition mechanism along their movement path, improving sample transport efficiency while also improving sample collection efficiency.
[0103] Specifically, after the first sample addition mechanism completes the collection of samples necessary for biochemical testing within the sample containers supported on the second sample rack, the second sample rack moves along the first rail 21 toward the sample rack transfer mechanism 23 and is transferred onto the relay rail 231.
[0104] Next, the first drive unit 232 drives the relay rail 231 so that it connects to the input / output end 221 of the second rail 22, and after the connection is made, it transfers the second sample rack to the second rail 22 to facilitate the collection of sample material necessary for electrolyte detection by the second sample addition mechanism.
[0105] Once the second sample addition mechanism has completed collecting the sample necessary for electrolyte detection in the second sample rack, the second sample rack moves to the inlet / outlet end 221 of the second rail 22 and is transferred onto the relay rail 231.
[0106] Subsequently, the first drive unit 232 drives the relay rail 231 to connect to the third supply end 241 of the third rail 24 and transfers the second sample rack to the third rail 24. Finally, the second sample rack moves away from the sample analyzer 100 via the third rail 24.
[0107] Alternatively, after the second sample rack enters the sample analyzer 100 from the first rail 21, the first sample addition mechanism collects the sample necessary for biochemical testing from the sample containers carried on the second sample rack located on the first rail 21. After the first sample addition mechanism has completed sampling, the aforementioned second drive device drives the aforementioned gripper to grasp the aforementioned second sample rack and move the second sample rack onto the second rail 22.
[0108] After the second sample rack is transferred onto the second rail 22, the second sample addition mechanism collects the sample necessary for electrolyte detection from the sample container supported on the second sample rack.
[0109] After the second sample addition mechanism has completed sampling, the aforementioned second drive device drives the aforementioned gripper again so that the gripper clamps the second sample rack and moves it onto the third rail 24, and the second sample rack moves away from the sample analyzer 100 via the third rail 24.
[0110] Furthermore, the specimen analyzer 100 further includes a fourth rail 25 that can be used to transport at least the third specimen rack. The specimen containers carried on the aforementioned third specimen rack contain emergency specimens.
[0111] Specifically, the fourth rail 25 is parallel to the first rail 21, the second rail 22, and the third rail 24. Moreover, the intermediate rail 231 can be connected to the fourth rail 25. Alternatively, the aforementioned second drive device can drive the aforementioned gripper so as to grip the third sample rack on the fourth rail 25.
[0112] The aforementioned first sample addition mechanism can also collect emergency samples necessary for biochemical analysis from the third sample rack on the fourth rail 25.
[0113] Specifically, the first sample-adding arm 411 rotates around the second rotation center 413 such that the sampling needle of the first sample-adding arm 411 intersects with the fourth rail 25, forming the first emergency sampling point 251. The second sample-adding arm 412 rotates around the third rotation center 414 such that the sampling needle of the second sample-adding arm 412 intersects with the fourth rail 25, forming the second emergency sampling point 252.
[0114] The third sample rack moves along the fourth rail 25 such that the multiple sample containers carried on the third sample rack pass sequentially through the second emergency sampling point 252 and the first emergency sampling point 251.
[0115] In the single-ring reaction disk 10, the aforementioned first sample addition mechanism samples from a sample container located at the first emergency sampling point 251 and transfers and injects it into the reaction vessel located at the discharge position.
[0116] In the double-ring reaction disk 10, the sampling needle of the first sample addition arm 411 samples from the sample container located at the first emergency sampling point 251 and transfers it to the reaction vessel located at the inner sample discharge position 121. The sampling needle of the second sample addition arm 412 samples from the sample container located at the second emergency sampling point 252 and transfers it to the reaction vessel located at the outer sample discharge position 111.
[0117] Furthermore, a first washing position 415 is provided below the trajectory of the sampling needle of the first sample-adding arm 411. This first washing position 415 is located between the common sampling point 211 and the inner sample discharge position 121 along the trajectory of the sampling needle, and is far from the second rotation center 413. A second washing position 416 is provided below the trajectory of the sampling needle of the second sample-adding arm 412. This second washing position 416 is located between the common sampling point 211 and the outer sample discharge position 111 along the aforementioned trajectory of the sampling needle, and is far from the second rotation center 413.
[0118] In one embodiment, a second sample rack, which is transported solely for biochemical testing, can also enter the sample analyzer 100 via the fourth rail 25 and be transferred from the fourth rail 25 to the second rail 22 via the sample rack transfer mechanism 23.
[0119] Specifically, if a sample in a sample container carried on the first or second sample rack on the first rail 21 is sampled by the first sample addition mechanism, and no emergency samples for biochemical analysis are being transported to the fourth rail 25, the second sample rack, which contains only electrolyte detection samples, enters the sample analyzer 100 along the fourth rail 25 and is transferred to the second rail 22 via the sample rack transfer mechanism 23, facilitating sampling by the second sample addition mechanism.
[0120] Furthermore, the sample analyzer 100 further comprises a reagent container storage mechanism and a reagent injection mechanism. The aforementioned reagent container storage mechanism includes a first reagent container storage mechanism and a second reagent container storage mechanism. The aforementioned reagent injection mechanism includes a first reagent injection mechanism 62 and a second reagent injection mechanism 63.
[0121] The aforementioned first reagent container storage mechanism is provided on the outside of the reaction disk 10 and can accommodate multiple reagent containers. Furthermore, the aforementioned first reagent container storage mechanism is rotatable so as to move the multiple reagent containers along the first rotation path.
[0122] The aforementioned first reagent container storage mechanism has multiple first mounting positions formed along the aforementioned first rotational path. Each of the aforementioned first mounting positions can accommodate one reagent container.
[0123] The aforementioned first reagent container storage mechanism includes a first reagent aspiration position 51 and a second reagent aspiration position 52. By rotating around a first rotation center 535, the aforementioned first reagent container storage mechanism can move multiple first mounting positions, allowing the first reagent aspiration position 51 and the second reagent aspiration position 52 to pass through them sequentially.
[0124] The reaction disk 10 can accommodate multiple reaction vessels. The reaction disk 10 is rotatable to move the multiple reaction vessels along the third rotation path.
[0125] Specifically, if the reaction disk 10 has a single-ring structure, the reaction disk 10 has multiple third mounting positions formed along the aforementioned third rotational path. Each of the aforementioned third mounting positions can accommodate one reaction vessel.
[0126] The reaction disk 10 includes a first reagent dispensing position 13 and a second reagent dispensing position 14. By rotating the reaction disk 10 around a third rotation center 15, multiple third mounting positions can be moved so that they sequentially pass through the aforementioned first reagent dispensing position 13 and second reagent dispensing position 14.
[0127] The first reagent injection mechanism 62 includes a first reagent needle 61 and a second reagent needle, both of which operate independently. The first reagent needle 61 is used to aspirate a reagent from a reagent container located at either the first reagent aspiration position 51 or the second reagent aspiration position 52, and to transfer and discharge the reagent along the first straight line 551 into a reaction vessel located at either the first reagent discharge position 13 or the second reagent discharge position 14. The second reagent needle is used to aspirate a reagent from a reagent container located at the other of the first reagent aspiration position 51 or the second reagent aspiration position 52, and to transfer and discharge the reagent along the second straight line 552 into a reaction vessel located at the other of the first reagent discharge position 13 or the second reagent discharge position 14.
[0128] After the reaction disk 10 rotates to move the two target reaction vessels to the first reagent dispensing position 13 and the second reagent dispensing position 14, respectively, and after the aforementioned first reagent container storage mechanism rotates to move the two target reagent containers to the first reagent aspiration position 51 and the second reagent aspiration position 52, respectively, the first reagent needle 61 aspirates a reagent from the target reagent container located at either the first reagent aspiration position 51 or the second reagent aspiration position 52, and transfers the aspirated reagent along the first straight line 551 to inject it into the target reaction vessel located at either the first reagent dispensing position 13 or the second reagent dispensing position 14.
[0129] The second reagent needle aspirates reagent from the target reagent container located at the other of the first reagent aspiration position 51 or the second reagent aspiration position 52, and transfers the aspirated reagent along the second straight line 552 to inject it into the target reaction vessel located at the other of the first reagent discharge position 13 or the second reagent discharge position 14.
[0130] Compared to the reagent injection method of the conventional sample analyzer 100, this embodiment transfers reagents along the first straight line 551 using an independently operating first reagent needle 61, and transports reagents along the second straight line 552 using an independently operating second reagent needle. As a result, the efficiency of reagent injection into the reaction vessel is significantly improved, the aspiration and injection of reagents by the first reagent needle 61 and the second reagent needle are avoided, the rotation and reset of the aspiration reagent are avoided, the time the reaction disk 10 has to wait for the first reagent needle 61 and the second reagent needle to inject the reagent is effectively reduced, the time the first reagent container storage mechanism has to wait for the first reagent needle 61 and the second reagent needle to aspiration the reagent is reduced, and the reagent transfer time and the reset time of the first reagent needle 61 and the second reagent needle are reduced. In addition, the independently operating first reagent needle 61 and the second reagent needle can be controlled to transfer reagents by controlling only the first reagent needle 61 or the second reagent needle as needed.
[0131] In one embodiment, the first reagent container storage mechanism is a single-ring structure. The aforementioned plurality of first mounting positions transport the reaction vessel along the aforementioned first rotational path around the first rotation center 535.
[0132] In another embodiment, the aforementioned first reagent container storage mechanism has a double-ring structure and includes a first reagent container storage inner plate 531 and a first reagent container storage outer plate 533. The aforementioned first reagent container storage inner plate 531 is located inside the first reagent container storage outer plate 533.
[0133] Multiple first internal mounting positions 532 are formed in the first reagent container storage inner panel 531 along the first internal rotation path. Each first internal mounting position 532 can accommodate one reagent container.
[0134] The outer panel 533 for storing the first reagent container has a plurality of first external mounting positions 534 formed along the first external rotation path. Each first external mounting position 534 can accommodate one reagent container.
[0135] Furthermore, in one more specific embodiment, the first reagent aspiration position 51 is provided in the first internal rotation path of the first reagent container storage inner plate 531, and a plurality of first internal mounting positions 532 move along the aforementioned first internal rotation path and sequentially pass the first reagent aspiration position 51, and the second reagent aspiration position 52 is provided in the first external rotation path of the first reagent container storage outer plate 533, and a plurality of first external mounting positions 534 move along the aforementioned first external rotation path and sequentially pass the second reagent aspiration position 52.
[0136] In another, more specific embodiment, the first reagent aspiration position 51 is located in the aforementioned first external rotation path of the first reagent container storage outer plate 533, and a plurality of first external mounting positions 534 move along the aforementioned first external rotation path, sequentially passing the first reagent aspiration position 51. The second reagent aspiration position 52 is located in the aforementioned first internal rotation path of the first reagent container storage inner plate 531. A plurality of the aforementioned first internal mounting positions 532 move along the aforementioned first internal rotation path, sequentially passing the second reagent aspiration position 52.
[0137] In one embodiment, the inner plate 531 for storing the first reagent container and the outer plate 533 for storing the first reagent container maintain synchronous rotation.
[0138] In another embodiment, the inner plate 531 for storing the first reagent container is rotatable independently of the outer plate 533 for storing the first reagent container. That is, when the inner plate 531 for storing the first reagent container rotates, the outer plate 533 for storing the first reagent container may remain stationary or rotate with the same number of rotations as the inner plate 531 or a different number of rotations. Alternatively, when the outer plate 533 for storing the first reagent container rotates, the inner plate 531 for storing the first reagent container may remain stationary or rotate with the same number of rotations as the outer plate 533 or a different number of rotations.
[0139] Furthermore, the independently rotatable first reagent container storage inner plate 531 can be controlled so that the target reagent container, depending on the type of reagent to be aspirated from the reagent container placed in the first inner mounting position 532, moves directly to the first reagent aspiration position 51 or the second reagent aspiration position 52 corresponding to the first reagent needle 61.
[0140] The independently rotatable first reagent container storage outer plate 533 can be controlled so that the target reagent container, placed on the first external mounting position 534, moves directly to the second reagent aspiration position 52 or the first reagent aspiration position 51, which corresponds to the second reagent needle, depending on the type of reagent to be aspirated in the reagent container.
[0141] To maintain the synchronous rotation of the first reagent container storage inner plate 531 and the first reagent container storage outer plate 533, the independently rotatable first reagent container storage inner plate 531 and first reagent container storage outer plate 533 facilitate the aspiration of reagents by the first reagent needle 61 and the second reagent needle. Specifically, when the first reagent needle 61 aspirates a reagent from a target reagent container, the target reagent container corresponding to the second reagent needle cannot simultaneously reach the second reagent aspiration position 52. As a result, after the first reagent needle 61 aspirates the reagent from the target reagent container, the reaction disk 10 rotates again to move the target reagent container corresponding to the second reagent needle to the second reagent aspiration position 52, thereby avoiding the second reagent needle from performing aspiration. In this process, the target reagent container corresponding to the second reagent needle needs to stop twice due to the rotation of the reaction disk 10 in order to reach the second reagent aspiration position 52.
[0142] Furthermore, in a more specific embodiment, the first reagent dispensing position 13 is located in the aforementioned third internal rotation path of the reaction inner tray 12. Multiple third internal mounting positions 122 move along the aforementioned third internal rotation path and sequentially pass the first reagent dispensing position 13.
[0143] The second reagent dispensing position 14 is located in the aforementioned third external rotation path of the reaction outer tray 11. Multiple third external mounting positions 112 move along the aforementioned third external rotation path and sequentially pass through the second reagent dispensing position 14.
[0144] In another, more specific embodiment, the first reagent dispensing position 13 is located in the aforementioned third external rotation path of the reaction outer tray 11, and a plurality of third external mounting positions 112 move along the aforementioned third external rotation path and sequentially pass the first reagent dispensing position 13.
[0145] The second reagent dispensing position 14 is located in the aforementioned third internal rotation path of the reaction inner tray 12, and the multiple third internal mounting positions 122 move along the aforementioned third internal rotation path and sequentially pass through the second reagent dispensing position 14.
[0146] In one embodiment, the reaction inner tray 12 and the reaction outer tray 11 maintain synchronous rotation.
[0147] In another embodiment, the reaction inner tray 12 is rotatable independently of the reaction outer tray 11. That is, when the reaction inner tray 12 rotates, the reaction outer tray 11 may remain stationary or rotate by the same number of rotations as the reaction inner tray 12 or a different number of rotations. Alternatively, when the reaction outer tray 11 rotates, the reaction inner tray 12 may remain stationary or rotate by the same number of rotations as the reaction outer tray 11 or a different number of rotations.
[0148] Furthermore, the independently rotatable reaction inner tray 12 can be controlled to move directly to the first reagent dispensing position 13 or the second reagent dispensing position 14, which corresponds to the first reagent needle 61, depending on the type of reagent to be injected into the reaction vessel placed in the third internal mounting position 122.
[0149] The independently rotatable reaction outer tray 11 can be controlled so that the target reaction vessel, placed on the third external mounting position 112, moves directly to the second reagent dispensing position 14 or the first reagent dispensing position 13, which corresponds to the second reagent needle, depending on the type of reagent to be injected into the reaction vessel.
[0150] Compared to the synchronous rotation of the inner reaction tray 12 and the outer reaction tray 11, the independent rotation of the inner reaction tray 12 and the outer reaction tray 11 makes it easier to inject reagents using the first reagent needle 61 and the second reagent needle.
[0151] Furthermore, by providing an independently rotatable inner reaction tray 12 and outer reaction tray 11, and an independently rotatable inner first reagent container storage plate 531 and outer first reagent container storage plate 533, and by injecting reagents placed on the outer first reagent container storage plate 533 into reaction vessels placed on the inner reaction tray 12 or outer reaction tray 11 via an independently operating first reagent needle 61, and injecting reagents placed on the inner first reagent container storage plate 531 into reaction vessels placed on the outer reaction tray 11 or inner reaction tray 12 via an independently operating second reagent needle, the sample analyzer 100 integrates two independent parallel reagent supply, dispensing, and detection systems, effectively improving detection efficiency.
[0152] Furthermore, in one embodiment, a first center connection is formed between the first rotation center 535 and the third rotation center 15. The first straight line 551 is either parallel to the aforementioned first center connection, intersects the aforementioned first center connection directly, or intersects with the extension of the aforementioned first center connection. The second straight line 552 is either parallel to the aforementioned first center connection, intersects the aforementioned first center connection directly, or intersects with the extension of the aforementioned first center connection.
[0153] Preferably, the first straight line 551 and the second straight line 552 are parallel to the first center connection described above. Moreover, the distance from the first straight line 551 to the first center connection is equal to the distance from the second straight line 552 to the first center connection.
[0154] Furthermore, the time required for the first reagent needle 61 to move along the first straight line 551 from the first reagent aspiration position 51 to the first reagent dispensing position 13 is the same as the time required for the second reagent needle to move along the second straight line 552 from the second reagent aspiration position 52 to the second reagent dispensing position 14.
[0155] Furthermore, in one embodiment, the first reagent needle 61 and the second reagent needle are each provided on the stand at a certain distance apart.
[0156] Furthermore, the first reagent needle 61 is moved vertically up and down by a lifting drive device. This allows the first reagent needle 61 to move vertically at either the first reagent aspiration position 51 or the second reagent aspiration position 52, and at either the first reagent dispensing position 13 or the second reagent dispensing position 14.
[0157] Furthermore, the first reagent needle 61 moves horizontally along the direction of the first straight line 551 by a horizontal drive device. This allows the first reagent needle 61 to move between the first reagent aspiration position 51 and the first reagent dispensing position 13 or the second reagent dispensing position 14, or between the second reagent aspiration position 52 and the second reagent dispensing position 14 or the first reagent dispensing position 13.
[0158] The aforementioned second reagent needle is moved vertically by a separate lifting drive device. This allows the aforementioned second reagent needle to move vertically between the first reagent aspiration position 51 and the second reagent aspiration position 52, and between the first reagent dispensing position 13 and the second reagent dispensing position 14.
[0159] Furthermore, the second reagent needle is moved horizontally along the direction of the second straight line 552 by another horizontal drive device. This allows the aforementioned second reagent needle to move between the first reagent aspiration position 51 and the first reagent dispensing position 13 or the second reagent dispensing position 14, or between the second reagent aspiration position 52 and the second reagent dispensing position 14 or the first reagent dispensing position 13.
[0160] In another embodiment, the first reagent needle 61 and the second reagent needle are mounted on the same stand. The first reagent needle 61 and the aforementioned second reagent needle are moved vertically by a lifting drive device and horizontally along the corresponding first straight line 551 and second straight line 552 by a horizontal drive device.
[0161] Furthermore, the reaction disk 10 further includes a third reagent dispensing position 16 and a fourth reagent dispensing position 17. In addition, by rotating the reaction disk 10 around the third rotation center 15, multiple third mounting positions can be sequentially passed through the third reagent dispensing position 16 and the fourth reagent dispensing position 17.
[0162] The second reagent injection mechanism 63 is used to inject reagents from the reagent containers placed on the second reagent container storage mechanism into the reaction vessel placed on the reaction disk 10.
[0163] The aforementioned second reagent container storage mechanism is located outside the reaction disk 10 and can accommodate multiple reagent containers. Furthermore, the aforementioned second reagent container storage mechanism is rotatable to move the multiple reagent containers along the second rotation path.
[0164] The aforementioned second reagent container storage mechanism has multiple second mounting positions formed along the aforementioned second rotational path. Each second mounting position can accommodate one reagent container.
[0165] The aforementioned second reagent container storage mechanism includes a third reagent aspiration position 57 and a fourth reagent aspiration position 58. By rotating around the second rotation center 545, the aforementioned second reagent container storage mechanism can sequentially pass through multiple second mounting positions to the third reagent aspiration position 57 and the fourth reagent aspiration position 58.
[0166] The second reagent injection mechanism 63 includes a third reagent needle and a fourth reagent needle that operate independently.
[0167] The aforementioned third reagent needle is used to aspirate a reagent from a reagent container located at either the third reagent aspiration position 57 or the fourth reagent aspiration position 58, and to transfer and discharge the reagent along the third straight line 561 into a reaction vessel located at either the third reagent discharge position 16 or the fourth reagent discharge position 17.
[0168] The aforementioned fourth reagent needle is used to aspirate a reagent from a reagent container located at the other of the third reagent aspiration position 57 or the fourth reagent aspiration position 58, and to transfer and discharge the reagent along the fourth straight line 562 into a reaction vessel located at the other of the third reagent discharge position 16 or the fourth reagent discharge position 17.
[0169] The reaction disk 10 rotates to move the two target reaction vessels to the third reagent dispensing position 16 and the fourth reagent dispensing position 17, respectively, and the second reagent container storage mechanism rotates to move the two target reagent containers to the third reagent aspiration position 57 and the fourth reagent aspiration position 58, respectively. Then, the third reagent needle aspirates a reagent from the target reagent container located at either the third reagent aspiration position 57 or the fourth reagent aspiration position 58, and transfers the aspirated reagent along the third straight line 561 to inject it into the target reaction vessel located at either the third reagent dispensing position 16 or the fourth reagent dispensing position 17.
[0170] The aforementioned fourth reagent needle aspirates a reagent from the target reagent container located at the other of the third reagent aspiration position 57 or the fourth reagent aspiration position 58, and transfers the aspirated reagent along the fourth straight line 562 to inject it into the target reaction vessel located at the other of the third reagent discharge position 16 or the fourth reagent discharge position 17.
[0171] In one embodiment, the aforementioned second reagent container storage mechanism is a single-ring structure. The aforementioned plurality of second mounting positions transport the reaction vessel along the aforementioned second rotational path around the second rotation center 545.
[0172] In another embodiment, the second reagent container storage mechanism described above has a double-ring structure and includes a second reagent container storage inner plate 541 and a second reagent container storage outer plate 543. The second reagent container storage inner plate 541 is located inside the second reagent container storage outer plate 543.
[0173] The second reagent container storage inner panel 541 has multiple second internal mounting positions 542 formed along the second internal rotation path. Each second internal mounting position 542 can accommodate one reagent container.
[0174] The aforementioned second reagent container storage outer plate 543 has multiple second external mounting positions 544 formed along the second external rotation path. Each second external mounting position 544 can accommodate one reagent container.
[0175] Furthermore, in one more specific embodiment, the third reagent aspiration position 57 is provided in the aforementioned second internal rotation path of the second reagent container storage inner plate 541, and the aforementioned plurality of second internal mounting positions 542 move along the aforementioned second internal rotation path and sequentially pass the third reagent aspiration position 57. The aforementioned fourth reagent aspiration position 58 is provided in the aforementioned second external rotation path of the second reagent container storage outer plate 543. The aforementioned plurality of second external mounting positions 544 move along the aforementioned second external rotation path and sequentially pass the fourth reagent aspiration position 58.
[0176] In another, more specific embodiment, the third reagent aspiration position 57 is located in the aforementioned second external rotation path of the second reagent container storage outer plate 543, and the aforementioned multiple second external mounting positions 544 move along the aforementioned first external rotation path and sequentially pass through the third reagent aspiration position 57.
[0177] The fourth reagent aspiration position 58 is located in the aforementioned second internal rotation path of the second reagent container storage inner plate 541, and the aforementioned multiple second internal mounting positions 542 move along the aforementioned second internal rotation path and sequentially pass through the fourth reagent aspiration position 58.
[0178] In one embodiment, the inner plate 541 and the outer plate 543 of the second reagent container maintain synchronous rotation.
[0179] In another embodiment, the second reagent container storage inner plate 541 is rotatable independently of the second reagent container storage outer plate 543. That is, when the second reagent container storage inner plate 541 rotates, the second reagent container storage outer plate 543 may remain stationary or rotate by the same number of rotations as the second reagent container storage inner plate 541 or a different number of rotations. Alternatively, when the second reagent container storage outer plate 543 rotates, the second reagent container storage inner plate 541 may remain stationary or rotate by the same number of rotations as the second reagent container storage outer plate 543 or a different number of rotations.
[0180] Furthermore, the independently rotatable second reagent container storage inner plate 541 can be controlled so that the aforementioned target reagent container moves directly to the third reagent aspiration position 57 or the fourth reagent aspiration position 58, which corresponds to the third reagent needle, depending on the type of reagent to be aspirated from the reagent container placed in the second inner mounting position 542.
[0181] The independently rotatable second reagent container storage outer plate 543 can be controlled so that the target reagent container, depending on the type of reagent to be aspirated from the reagent container placed on the second external mounting position 544, moves directly to the third reagent aspiration position 57 or the fourth reagent aspiration position 58, which corresponds to the fourth reagent needle.
[0182] Furthermore, in one embodiment, a second center connection is formed between the second center of rotation 545 and the third center of rotation 15. The third straight line 561 is either parallel to the aforementioned second center connection, intersects the aforementioned second center connection directly, or intersects with the extension of the aforementioned second center connection. The fourth straight line 562 is either parallel to the aforementioned second center connection, intersects the aforementioned second center connection directly, or intersects with the extension of the aforementioned second center connection.
[0183] Preferably, the third line 561 and the fourth line 562 are parallel to the second centerline. Moreover, the distance from the third line 561 to the second centerline is equal to the distance from the fourth line 562 to the second centerline.
[0184] Furthermore, the reaction disk 10 has a horizontal symmetry line 102 and a vertical symmetry line 104 passing through the third rotation center 15. The horizontal symmetry line 102 and the vertical symmetry line 104 divide the reaction disk 10 into the first quadrant, the second quadrant, the third quadrant, and the fourth quadrant.
[0185] In one embodiment, the first rotation center 535 and the second rotation center 545 are located on opposite sides of the vertical symmetry line 104 and on the same side of the horizontal symmetry line 102. As a result, the first reagent container storage mechanism and the second reagent container storage mechanism are arranged to be distributed within the first and second quadrants and located outside the reaction disk 10, or distributed within the third and fourth quadrants and located outside the reaction disk 10.
[0186] In another embodiment, the first rotation center 535 and the second rotation center 545 are located on opposite sides of the horizontal symmetry line 102 and on the same side of the vertical symmetry line 104. As a result, the first reagent container storage mechanism and the second reagent container storage mechanism are arranged to be distributed within the first and fourth quadrants and located outside the reaction disk 10, or distributed within the second and third quadrants and located outside the reaction disk 10.
[0187] Specifically, the reaction disk 10, the aforementioned first reagent container storage mechanism, and the aforementioned second reagent container storage mechanism are all located on the stage. Furthermore, in order to facilitate the attachment and detachment of reagent containers to and from the first and second reagent container storage mechanisms, the aforementioned first and second reagent container storage mechanisms are located on the same side of the aforementioned stage.
[0188] Furthermore, a center line 103 is formed between the first rotation center 535 of the aforementioned first reagent container storage mechanism and the second rotation center 545 of the aforementioned second reagent container storage mechanism.
[0189] The foot of the vertical symmetry line 104 and the center line 103 is located at the midpoint of the center line 103.
[0190] Specifically, the straight-line distance from the first rotation center 535 to the third rotation center 15 is equal to the straight-line distance from the second rotation center 545 to the third rotation center 15. As a result, the triangle formed by the lines connecting the three points of the first rotation center 535, the second rotation center 545, and the third rotation center 15 is an isosceles triangle. Moreover, the aforementioned first reagent container storage mechanism and the second reagent container storage mechanism are distributed symmetrically on both sides of the reaction disk 10 along the vertical symmetry line 104.
[0191] As shown in Figure 3, in another embodiment, the present invention further provides a method for transporting a sample using a sample analyzer 100. This sample transport method comprises the following steps.
[0192] In step S10, the sample rack enters the sample analyzer 100 from the first supply end 212 of the first rail 21.
[0193] In this step, the first rail 21 is located outside the reaction disk 10. The reaction disk 10 is located on a stage and supports a reaction vessel for containing a sample requiring biochemical testing.
[0194] The aforementioned sample rack holds the sample containers. The samples in these containers are used for biochemical testing and / or electrolyte detection.
[0195] The first rail 21 is located outside the reaction disk 10 and is used to transport the aforementioned sample racks. It includes a first supply end 212 and a first discharge end 213. The first supply end 212 is the entry end where the sample racks enter the first rail 21, and the first discharge end 213 is the end where the sample racks leave the first rail 21.
[0196] In step S20, the aforementioned sample rack is moved from the first discharge end 213 of the first rail 21 to the sample rack transfer mechanism 23.
[0197] In this step, the specimen rack transfer mechanism 23 includes a relay rail 231 and a first drive unit 232. The first drive unit 232 drives the relay rail 231 to connect with the first discharge end 213 of the first rail 21 in order to facilitate the transfer of the first specimen rack or the second specimen rack on the first rail 21 to the relay rail 231.
[0198] Specifically, the aforementioned sample racks are transported via the first rail 21. Furthermore, after the relay rail 231 is connected to the first discharge end 213 of the first rail 21, the first rail 21 transports the sample racks so that they are transferred to the relay rail 231.
[0199] In step S30, the aforementioned sample rack is moved from the sample rack transfer mechanism 23 to the inlet / outlet end 221 of the second rail 22.
[0200] In this step, after the aforementioned sample rack is transferred to the relay rail 231, the first drive unit 232 drives the relay rail 231 on which the sample rack is placed to move it, so that the relay rail 231 is connected to the input / output end 221 of the second rail 22, and thereafter the aforementioned sample rack is transferred to the input / output end 221 of the second rail 22 via the relay rail 231.
[0201] In step S40, the aforementioned sample rack extends from the input / output end 221 to the second sampling zone of the second rail 22.
[0202] In this step, after the aforementioned sample rack reaches the inlet / outlet end 221 of the second rail 22, the sample rack is transported by the second rail 22 until it moves to the second sampling zone of the second rail 22.
[0203] In step S50, the second sample addition mechanism transfers the sample from the sample container supported on the aforementioned sample rack into the detection container supported on the electrolyte detection mechanism 30.
[0204] After the aforementioned sample rack moves to the aforementioned second sampling zone, the aforementioned second sample addition mechanism collects the sample necessary for electrolyte detection from the sample containers supported on the sample rack located in the second sampling zone, and injects the collected sample into the detection container located at the first sample injection position 31 or the second sample injection position 32.
[0205] After injecting the electrolyte detection sample into the aforementioned detection container, the electrolyte detection mechanism 30 performs electrolyte detection on the aforementioned sample.
[0206] In step S60, the second sample addition mechanism transfers the sample from the sample container supported on the aforementioned sample rack into the detection container supported on the electrolyte detection mechanism 30. After this, the sample rack moves from the second sampling zone to the inlet / outlet end 221 and then from the inlet / outlet end 221 to the sample rack transfer mechanism 23.
[0207] In this step, once the second sample addition mechanism has completed collecting samples from the sample containers supported on the aforementioned sample rack, the sample rack moves from the aforementioned second sampling zone toward the inlet / outlet end 221 until it reaches the inlet / outlet end 221.
[0208] Before or after the aforementioned sample rack reaches the input / output end 221, the first drive unit 232 drives the relay rail 231 to connect with the input / output end 221 of the second rail 22.
[0209] The second rail 22 transports the aforementioned sample rack after the relay rail 231 is connected to the input / output end 221, and moves it to the relay rail 231. After that, the sample rack is moved away from the sample analyzer 100 by the relay rail 231 and the second drive unit.
[0210] Furthermore, during the process in which the second sample addition mechanism transfers the sample from the sample container supported on the sample rack to the detection container, the aforementioned sample rack is placed on the second rail 22, and the aforementioned second sample addition mechanism moves into a different sample container supported by the said sample rack to collect the aforementioned sample.
[0211] Specifically, the sampling needle of the second sample addition mechanism can move into different sample containers supported by a sample rack placed on the second rail 22, and perform sampling.
[0212] In one embodiment, the second sample addition mechanism includes a folding arm and a sampling needle. The aforementioned folding arm can move the aforementioned sampling needle into different sample containers supported on the aforementioned sample rack to collect samples.
[0213] Specifically, the aforementioned folding arm includes at least a first sub-folding arm 422 and a second sub-folding arm 423. The first sub-folding arm 422 is rotatably mounted at one end around a first pivot center 421, and its other end is connected to one end of the second sub-folding arm 423. The second sub-folding arm 423 is rotatable relative to the first sub-folding arm 422. The other end of the second sub-folding arm 423 is connected to a sampling needle.
[0214] By positioning the aforementioned sampling needle on a folding arm, the sampling needle can sample within the second sampling zone on the second rail 22. Since the second sampling zone can accommodate at least one second sample rack, the aforementioned sampling needle can sample from any sample container in the second sample rack placed in the second sampling zone.
[0215] In another embodiment, the aforementioned second sample addition mechanism includes an extendable arm and a sampling needle. The extendable arm can move the sampling needle into different sample containers supported by the second sample rack, thereby allowing the sampling needle to collect samples.
[0216] Specifically, the aforementioned telescopic arm includes at least a first sub-telescopic arm and a second sub-telescopic arm. The first sub-folding arm is rotatably mounted at one end around a first pivot center 421, and its other end is connected to one end of the second sub-telescopic arm. The second sub-telescopic arm is extendable relative to the first sub-telescopic arm. The other end of the second sub-telescopic arm is connected to a sampling needle.
[0217] By mounting the sampling needle on the aforementioned telescopic arm, the sampling needle can sample within the second sampling zone on the second rail 22. Since the second sampling zone can accommodate at least one second sample rack, the sampling needle can sample from any of the sample containers in the second sample rack placed in the second sampling zone.
[0218] As shown in Figure 4, the aforementioned sample rack entering the sample analyzer 100 from the first supply end 212 of the first rail 21 further includes the following steps.
[0219] In step S11, the aforementioned sample rack extends from the first supply end 212 to the first sampling zone of the first rail 21, and the multiple sample containers carried on the sample rack sequentially pass through the common sampling point 211.
[0220] In this step, the aforementioned first sampling zone is located between the first supply end 212 and the first discharge end 213 on the first rail 21. The aforementioned sample rack moves along the first rail 21 so that each sample container in the sample rack sequentially reaches the common sampling point 211.
[0221] In step S12, as multiple sample containers sequentially pass through the common sampling point 211, the first sample addition mechanism transfers the samples from the sample containers located at the common sampling point 211 to the reaction containers placed on the reaction disk 10.
[0222] Specifically, the sample injected into the reaction vessel placed on the reaction disk 10 is used for biochemical testing.
[0223] In step S13, the first sample addition mechanism transfers the sample from the sample container located at the common sampling point 211 into the reaction vessel placed on the reaction disk 10. After this, the aforementioned sample rack moves from the first sampling zone to the first discharge end 213.
[0224] In this step, after the first sample addition mechanism has completed sampling from the sample containers carried on the sample rack located in the first sampling zone, the first rail 21 transports the sample rack and moves it from the first sampling zone to the first discharge end 213 in order to facilitate the transfer of the sample rack from the first discharge end 213 of the first rail 21 to the relay rail 231.
[0225] Furthermore, the first sample addition mechanism includes a first sample addition arm 411 and a second sample addition arm 412, both of which are independent of each other.
[0226] In this embodiment, the reaction disk 10 includes an outer reaction tray 11 and an inner reaction tray 12 provided inside the outer reaction tray 11.
[0227] In the process by which the aforementioned first sample addition mechanism transfers a sample from a sample container supported on the first sample rack to a reaction container supported on the reaction disk, the first sample addition arm 411 aspirates the first sample from one of the sample containers located at the common sampling point 211 and transfers the first sample into the reaction container placed on the reaction inner tray 12. In the process by which the first sample is transferred by the first sample addition arm 411 to the reaction container placed on the reaction inner tray 12, the second sample addition arm 412 aspirates the first sample from one of the sample containers located at the common sampling point 211 and transfers the first sample into the reaction container placed on the reaction outer tray 11. Alternatively, during the process in which the first sample is transferred by the first sample addition arm 411 to the reaction vessel placed on the reaction inner tray 12, the second sample addition arm 412 aspirates the second sample from another sample container located at the common sampling point 211 and transfers the second sample into the reaction vessel placed on the reaction outer tray 11.
[0228] Specifically, the aforementioned first sample addition mechanism includes a first sample addition arm 411 and a second sample addition arm 412. In the double-ring reaction disk 10, the sampling needle of the first sample addition arm 411 can transfer the sample collected from the common sampling point 211 into the reaction vessel placed on the inner reaction tray 12 or the outer reaction tray 11. The sampling needle of the second sample addition arm 412 can also transfer the sample collected from the common sampling point 211 into the reaction vessel placed on the inner reaction tray 12 or the outer reaction tray 11.
[0229] Preferably, the sampling needle of the first sample addition arm 411 is used to transfer the sample taken from the common sampling point 211 to the reaction vessel placed on the reaction inner tray 12, and the sampling needle of the second sample addition arm 412 is used to transfer the sample taken from the common sampling point 211 to the reaction vessel placed on the reaction outer tray 11.
[0230] In one specific embodiment, the sampling needle of the first sample addition arm 411 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction inner tray 12. The sampling needle of the second sample addition arm 412 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction outer tray 11.
[0231] As shown in Figure 3, after the aforementioned sample rack moves from the second sampling zone to the input / output end 221 and is transferred from the input / output end 221 to the sample rack transfer mechanism 23, the aforementioned sample transport method further comprises the following steps.
[0232] In step S70, the first drive unit 232 of the specimen rack transfer mechanism 23 drives the relay rail 231 to connect with the third supply end 241 of the third rail 24.
[0233] In this step, the sample analyzer 100 further includes a third rail 24 used for retrieving the sample rack. After the aforementioned second sample addition mechanism completes sampling with the sample rack, the sample rack transfer mechanism 23 transfers the sample rack to the third rail 24, and the sample rack moves away from the sample analyzer 100 through the third rail 24.
[0234] The first drive unit 232 drives the relay rail 231 so that it is connected to the first discharge end 213 of the first rail 21, the input / output end 221 of the second rail 22, and the third supply end 241 of the third rail 24, respectively. After the aforementioned second sample addition mechanism completes sampling from the sample rack, the second rail 22 moves to transport the sample rack to the relay rail 231. Subsequently, the first drive unit 232 drives the relay rail 231 on which the sample rack is placed so that it is connected to the third supply end 241 of the third rail 24.
[0235] In step S80, the aforementioned sample rack extends from the relay rail 231 to the third supply end 241.
[0236] In this step, after the relay rail 231 on which the aforementioned sample rack is placed is connected to the third supply end 241 of the third rail 24, the relay rail 231 moves to transport the sample rack to the third supply end 241 of the third rail 24.
[0237] In step S90, the aforementioned sample rack moves from the third supply end 241 to the third discharge end 242 of the third rail 24 and away from the sample analyzer 100.
[0238] In this step, the relay rail 231 moves to transport the aforementioned sample rack to the third supply end 241 of the third rail 24, after which the third rail 24 transports the sample rack away from the sample analyzer 100.
[0239] Referring to Figure 5, in yet another embodiment, the present invention provides a method for collecting a sample for a sample analyzer 100. This sample collection method comprises the following steps.
[0240] In step S100, in the first sampling zone, the first sample addition mechanism transfers the sample from the sample container supported on the first sample rack into the reaction vessel placed on the reaction disk 10.
[0241] In this step, the sample analyzer 100 includes a reaction disk 10, a first rail 21, and a first sample addition mechanism. The first rail 21 and the first sample addition mechanism are each located outside the reaction disk 10.
[0242] The aforementioned first sampling zone is located on the first rail 21. The aforementioned first sample addition mechanism is used to transfer the sample from the sample container, which is supported on the first sample rack located in the aforementioned first sampling zone, to the reaction vessel placed on the reaction disk 10, and to perform biochemical detection on the sample.
[0243] In step S200, in the second sampling zone, the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container supported on the electrolyte detection mechanism 30.
[0244] In this step, the sample analyzer 100 further includes a second rail 22 and a second sample addition mechanism, which are provided on the outside of the reaction disk 10. The second sampling zone is provided on the second rail 22.
[0245] The second sample addition mechanism and the first sample addition mechanism operate independently of each other. The aforementioned second sample addition mechanism is used to transfer a sample from a sample container supported on the second sample rack located in the aforementioned second sampling zone to a detection container supported on the electrolyte detection mechanism 30, and to perform electrolyte detection on the sample.
[0246] In step S300, the aforementioned second sample rack passes through the aforementioned first sampling zone in the process of being transferred to the second sampling zone.
[0247] In this step, the second rail 22 and the first rail 21 are parallel to each other. The sample analyzer 100 further includes a sample rack transfer mechanism 23 for transferring the second sample rack from the first rail 21 to the second rail 22.
[0248] Specifically, the second sample rack enters the first rail 21 from the first supply end 212 of the first rail 21, and then the second sample rack moves along the first rail 21 to the first discharge end 213 of the first rail 21, and is then transferred from the first discharge end 213 to the sample rack transfer mechanism 23.
[0249] Furthermore, in one embodiment, when the aforementioned second sample rack reaches the aforementioned first sampling zone, the aforementioned first sample addition mechanism transfers the sample from the sample container carried on the second sample rack to the aforementioned reaction vessel. Alternatively, when the aforementioned second sample rack reaches the aforementioned second sampling zone, the aforementioned second sample addition mechanism transfers the sample from the sample container carried on the second sample rack to the aforementioned detection vessel.
[0250] Specifically, in this embodiment, the specimens contained in the specimen containers supported on the second specimen rack need to undergo both biochemical testing and electrolyte detection.
[0251] Therefore, after the second sample rack moves to the first sampling zone on the first rail 21, the first sample addition mechanism samples the second sample rack for biochemical testing.
[0252] Once the first sample addition mechanism has completed sampling, the second sample rack is transferred to the second rail 22 under the action of the sample rack transfer mechanism 23, and moves along the second rail 22 to the second sampling zone.
[0253] After the second sample rack reaches the second sampling zone, the second sample addition mechanism samples the rack for electrolyte detection.
[0254] Furthermore, after the first sample addition mechanism transfers the sample from the sample container supported on the second sample rack to the aforementioned reaction vessel, the second sample rack moves from the first sampling zone to the first discharge end 213 of the first rail 21, and then from the first discharge end 213 to the sample rack transfer mechanism 23.
[0255] Specifically, the specimen rack transfer mechanism 23 includes a first drive unit 232 and a relay rail 231. The first drive unit 232 drives the relay rail 231 to connect to the first discharge end 213 of the first rail 21 and the inlet / outlet end 221 of the second rail 22, respectively.
[0256] After the relay rail 231 is connected to the first discharge end 213 of the first rail 21, the first rail 21 moves to transport the second sample rack from the first sampling zone to the first discharge end 213 of the first rail 21, and then transfers it from the first discharge end 213 to the relay rail 231.
[0257] The specimen rack transfer mechanism 23 transfers the aforementioned second specimen rack to the inlet / outlet end 221 of the second rail 22.
[0258] After the second sample rack is moved to the relay rail 231, the first drive unit 232 drives the relay rail 231, which is carrying the second sample rack, to move until it is connected to the input / output end 221 of the second rail 22.
[0259] After the relay rail 231 is connected to the input / output end 221 of the second rail 22, the relay rail 231 moves to transport the second sample rack to the input / output end 221 of the second rail 22.
[0260] After the aforementioned second sample rack reaches the aforementioned second sampling zone from the input / output end 221, the aforementioned second sample addition mechanism transfers the sample from the sample container placed on the second sample rack into the detection container placed on the electrolyte detection mechanism 30.
[0261] After the second sample rack is transported to the inlet / outlet end 221 of the second rail 22, the second rail 22 continues to transport the second sample rack to the second sampling zone, so that the second sample addition mechanism can collect the sample necessary for electrolyte detection.
[0262] After the second sample addition mechanism transfers the sample from the sample container carried on the second sample rack to the aforementioned detection container, the second sample rack reaches the aforementioned inlet / outlet end 221 from the second sampling zone and then moves from the inlet / outlet end 221 to the sample rack transfer mechanism 23.
[0263] Specifically, once the second sample addition mechanism has completed collecting the sample necessary for electrolyte detection, the second sample rack moves to the inlet / outlet end 221 of the second rail 22.
[0264] After the second sample rack reaches the inlet / outlet end 221 of the second rail 22, the second rail 22 moves to transfer the second sample rack to the relay rail 231.
[0265] Furthermore, in the process of transferring the sample from the sample containers supported on the second sample rack to the aforementioned detection container, the second sample addition mechanism can move into different sample containers supported on the second sample rack in order to collect samples, since the second sample rack is placed in the second sampling zone.
[0266] In this embodiment, the sampling needle of the second sample addition mechanism described above can move to different sample containers supported by the second sample rack, which is placed on the second rail 22, and sample can be taken from there.
[0267] In one embodiment, the second sample addition mechanism includes a folding arm and a sampling needle. The aforementioned folding arm can move the aforementioned sampling needle into different sample containers supported on the aforementioned second sample rack to collect samples.
[0268] Specifically, the aforementioned folding arm includes at least a first sub-folding arm 422 and a second sub-folding arm 423. One end of the first sub-folding arm 422 is rotatably mounted around a first pivot center 421, and the other end of the first sub-folding arm 422 is connected to one end of the second sub-folding arm 423. The second sub-folding arm 423 is rotatable relative to the first sub-folding arm 422. The other end of the second sub-folding arm 423 is connected to a sampling needle.
[0269] By positioning the sampling needle on a folding arm, the sampling needle can be made to sample within a second sampling zone on the second rail 22. The second sampling zone can accommodate at least one second sample rack. This allows the aforementioned sampling needle to sample from any of the sample containers in the second sample rack placed in the second sampling zone.
[0270] In another embodiment, the aforementioned second sample addition mechanism includes a telescopic arm and a sampling needle. The telescopic arm can move the sampling needle and move it into different sample containers supported by the second sample rack to sample a sample.
[0271] Specifically, the aforementioned telescopic arm includes at least a first sub-telescopic arm and a second sub-telescopic arm. One end of the first sub-telescopic arm is rotatably mounted around a first pivot center 421, and the other end of the first sub-telescopic arm is connected to one end of the second sub-telescopic arm. The second sub-telescopic arm is also extendable relative to the first sub-telescopic arm. The other end of the second sub-telescopic arm is connected to a sampling needle.
[0272] By positioning the aforementioned sampling needle on the aforementioned telescopic arm, the aforementioned sampling needle can be used to sample within the second sampling zone on the second rail 22. Since the second sampling zone can accommodate at least one second sample rack, the aforementioned sampling needle can sample from any of the sample containers in the second sample rack placed in the second sampling zone.
[0273] Furthermore, in the process of transferring samples from sample containers carried on the first sample rack to the reaction vessel, the first sample addition mechanism transfers the samples from the sample containers carried on the first sample rack to the common sampling point 211 located in the first sampling zone, and the first sample addition mechanism transfers the samples from the sample containers located at the common sampling point 211 to the reaction vessel.
[0274] In one embodiment, the aforementioned first sample addition mechanism includes a first sample addition arm 411 and a second sample addition arm 412, which are independent of each other.
[0275] The reaction disk 10 includes a reaction outer tray 11 and a reaction inner tray 12 provided inside the reaction outer tray 11. The aforementioned first sample addition mechanism includes a first sample addition arm 411 and a second sample addition arm 412. Both the first sample addition arm 411 and the second sample addition arm 412 sample at the common sampling point 211 in the aforementioned first sampling zone. The first sample rack moves on the first rail 21 so that each sample container in the first sample rack reaches the aforementioned common sampling point 211.
[0276] Specifically, the movement trajectories of the sampling needles of the first sample addition arm 411 and the second sample addition arm 412 intersect at the aforementioned common sampling point 211 on the first rail 21 such that the sampling needles of both the first sample addition arm 411 and the second sample addition arm 412 sample at the aforementioned common sampling point 211.
[0277] For the reaction disk 10 with a double-ring structure, the sample collected at the common sampling point 211 can be transferred into the reaction container placed on the reaction inner tray 12 or the reaction outer tray 11 using the sampling needle of the first sample addition arm 411. The sampling needle of the second sample addition arm 412 can also be used to transfer the sample collected at the common sampling point 211 into the reaction container placed on the reaction inner tray 12 or the reaction outer tray 11.
[0278] Preferably, the sampling needle of the first sample addition arm 411 is used to transfer the sample collected at the common sampling point 211 into the reaction container placed on the reaction inner tray 12, and the sampling needle of the second sample addition arm 412 is used to transfer the sample collected at the common sampling point 211 into the reaction container placed on the reaction outer tray 11.
[0279] Furthermore, the first rotation center 421 and the second rotation center 413 are located on opposite sides of the vertical symmetry line 104, respectively. The third rotation center 414 and the second rotation center 413 are located on the same side of the vertical symmetry line 104. As a result, the first sample addition mechanism and the second sample addition mechanism are positioned on opposite sides of the vertical symmetry line 104, respectively. Therefore, the first sample addition mechanism and the second sample addition mechanism can avoid interfering with each other when injecting biochemical test samples and electrolyte detection samples, respectively.
[0280] Furthermore, the second rotation center 413 is located between the first rotation center 421 and the third rotation center 414. In one specific embodiment, the sampling needle of the first sample addition arm 411 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction inner tray 12, and the sampling needle of the second sample addition arm 412 is used to inject the sample from the sample container at the common sampling point 211 into the reaction vessel placed on the reaction outer tray 11.
[0281] For the sake of clarity, spatial relative terms such as "above," "above," "on the top surface," and "on the top" can be used here to describe the spatial positional relationship between one element or feature shown in the drawing and another element or feature. It should be understood that spatial relative terms are intended to include different orientations of use or operation of the element other than the orientation described in the drawing. For example, if the element in the drawing is upside down, an element described as "above another element or structure" or "on top of another element or structure" would then be positioned as "below the other element or structure" or "below the other element or structure." Thus, the exemplary term "above" can include two orientations: "above" and "below." This element may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used here should be interpreted accordingly.
[0282] Furthermore, using terms such as "first" and "second" to specify parts is merely to make it easier to distinguish the relevant parts, and unless specifically declared, these terms have no special meaning and cannot be understood as a limitation on the scope of protection of this application.
[0283] The foregoing are merely preferred embodiments of the present application and are not intended to limit it, and to those skilled in the art, the present application may be subject to various modifications and changes. Any modifications, equivalent substitutions, improvements, etc., made in the spirit and principles of the present application should be included within the scope of protection. [Explanation of Symbols]
[0284] 100: Sample analyzer 102: Horizontal Symmetry 103: Center line 104: Vertical Symmetry Line 10: Reaction Disk 11: Reaction outer tray 111: External sample ejection position 112: 3rd external placement position 12: Reaction inner tray 121: Internal sample ejection position 122: 3rd inner placement position 13: First reagent dispensing position 14: Second reagent dispensing position 15: Center of the third rotation 16: Third reagent dispensing position 17: Fourth reagent dispensing position 21: First Rail 211: Common sampling point 212: 1st supply end 213: 1st discharge end 22: Second rail 221: Input / Output Terminal 23: Specimen rack transfer mechanism 231: Relay Rail 232: First drive unit 24: Third Rail 241: 3rd supply end 242: 3rd discharge end 25: Fourth rail 251: First emergency sampling point 252: Second emergency sampling point 30: Electrolyte detection mechanism 31: First specimen injection position 32: Second specimen injection position 411: First specimen addition arm 412: Second specimen addition arm 413: Second rotation center 414: Third rotation center 415: First washing position 416: Second washing position 421: First rotation center 422: First sub-foldable arm 423: Second sub-foldable arm 51: First reagent suction position 52: Second reagent suction position 531: First reagent container storage inner plate 532: First inner placement position 533: First reagent container storage outer plate 534: First outer placement position 535: First rotation center 541: Second reagent container storage inner plate 542: Second inner placement position 543: Second reagent container storage outer plate 544: Second outer placement position 545: Second rotation center 551: First straight line 552: Second straight line 561: Third straight line 562: Fourth straight line 57: Third reagent suction position 58: Fourth reagent suction position 61: First reagent needle 62: First reagent injection mechanism 63: Second reagent injection mechanism
Claims
1. A specimen analysis device, A first rail (21) including a first supply end (212) and a first discharge end (213) arranged opposite each other, The second rail (22) includes the input / output end (221), A third rail (24) including a third supply end (241) and a third discharge end (242) arranged opposite each other, The reaction disk (10) on which the reaction vessel is placed, The electrolyte detection mechanism (30) on which the detection container is placed, A first sample addition mechanism for transferring the sample located on the first rail (21) into the reaction vessel, The system includes a second sample addition mechanism for transferring the sample located on the second rail (22) into the detection container, The first discharge end (213), the input / output end (221), and the third supply end (241) are located at the same end of the sample analyzer, while the first supply end (212) and the third discharge end (242) are both located at the other end opposite to the aforementioned end. The samples located on the first rail (21) and the samples located on the second rail (22) enter the sample analyzer via the first supply end (212) of the first rail (21). Here, the samples contained in the sample containers supported on the first sample rack are transferred only to the reaction vessel. The sample contained in the sample container supported on the second sample rack is transferred to the detection container, or transferred to both the reaction container and the detection container. The sample analyzer further comprises a sample rack transfer mechanism (23), and the second sample rack is transferred from the first rail (21) to the second rail (22) via the sample rack transfer mechanism (23). The first sample rack and the second sample rack are separated from the sample analyzer via the third discharge end (242) of the third rail (24). The specimen analyzer is characterized in that the specimen rack transfer mechanism (23) is used to transfer the first specimen rack on the first rail (21) or the second specimen rack on the second rail (22) to the third rail (24).
2. The reaction disk (10) has a horizontal symmetry line (102) and a vertical symmetry line (104), The sample analyzer according to claim 1, characterized in that the electrolyte detection mechanism (30), the first rotation center (421) of the second sample addition mechanism, and the second rail (22) are provided between the first rail (21) and the horizontal symmetry line (102) and are located on the same side of the vertical symmetry line (104).
3. When the second sample addition mechanism transfers the sample on the second rail (22) to the detection container, the second sample rack is placed on the second rail (22), and the second sample addition mechanism moves into a different sample container supported on the second sample rack to collect a sample. The sample analyzer according to claim 1 or 2, characterized in that the second sample addition mechanism takes a sample from only one of the different sample containers each time.
4. The second sample addition mechanism includes a folding arm and a sampling needle, the folding arm moves the sampling needle into different sample containers supported by the second sample rack, and collects a sample with the sampling needle, or The specimen analyzer according to claim 3, wherein the second specimen addition mechanism includes an extendable arm and a sampling needle, the extendable arm moves the sampling needle into different specimen containers supported by the second specimen rack, and the sampling needle collects a sample.
5. The first sample addition mechanism includes a first sample addition arm (411) and a second sample addition arm (412), which are independent of each other. The first sample-adding arm (411) rotates around the second rotation center (413), and the second sample-adding arm (412) rotates around the third rotation center (414). The first pivot center (421) and the second pivot center (413) are provided on both sides of the vertical symmetry line (104), The sample analyzer according to claim 2, characterized in that the third rotation center (414) and the second rotation center (413) are located on the same side of the vertical symmetry line (104), and the second rotation center (413) is located between the first rotation center (421) and the third rotation center (414).
6. The reaction disc (10) includes an outer reaction tray (11) and an inner reaction tray (12) provided inside the outer reaction tray (11). The first sample addition arm (411) is used to transfer the sample located on the first rail (21) into the reaction vessel placed on the reaction inner tray (12). The second sample addition arm (412) transfers the sample located on the first rail (21) into the reaction vessel supported on the reaction outer tray (11), Here, both the first sample-adding arm (411) and the second sample-adding arm (412) sample at the common sampling point (211) on the first rail. The specimen analyzer according to claim 5, characterized in that the first specimen rack moves along the first rail (21) so that each specimen container in the first specimen rack sequentially reaches the common sampling point (211).
7. The reaction disk (10) includes a first reagent dispensing position (13) and a second reagent dispensing position (14). The aforementioned sample analyzer further comprises a reagent container storage mechanism, The reagent container storage mechanism is for placing reagent containers and is located outside the reaction disk (10) and on the side of the horizontal symmetry line (102) away from the electrolyte detection mechanism (30). The reagent container storage mechanism includes a first reagent aspiration position (51) and a second reagent aspiration position (52). The sample analyzer further comprises a reagent injection mechanism, the reagent injection mechanism further includes an independently controlled first reagent needle (61) and a second reagent needle. The first reagent needle (61) is used to aspirate a reagent from the reagent container located at the first reagent aspiration position (51), and to transfer and discharge the reagent along a first straight line into the reaction vessel located at the first reagent discharge position (13). The sample analyzer according to claim 2, characterized in that the second reagent needle is used to aspirate a reagent in the reagent container located at the second reagent aspiration position (52) and to transfer and discharge the reagent along the second straight line into the reaction vessel located at the second reagent discharge position (14).
8. The first rail (21), the second rail (22), and the third rail (24) are parallel to each other, The first sample rack and the second sample rack are separated from the sample analyzer via the third rail (24). The specimen rack transfer mechanism (23) is further used to transfer the first specimen rack on the first rail (21) or the second specimen rack on the second rail (22) to the third rail (24). Here, the sample rack transfer mechanism (23) includes a relay rail (231) and a first drive device (232), The first drive unit (232) drives the intermediate rail (231) to connect with the first discharge end (213) of the first rail (21), or drives the intermediate rail (231) to connect with the front output end (221) of the second rail (22), or drives the intermediate rail (231) to connect with the third supply end (241) of the third rail (24), Alternatively, the specimen rack transfer mechanism (23) includes a second drive unit and a gripper, The specimen analyzer according to claim 1, characterized in that, under the drive of the second drive device, the gripper moves the second specimen rack on the first rail (21) to the second rail (22), and moves the second specimen rack on the second rail (22) and the first specimen rack on the second rail (21) to the third rail (24).
9. The first rail (21) is used to transport the first sample rack and the second sample rack. The first sample rack is for placing samples that require biochemical testing, and the second sample rack is for placing samples that require electrolyte detection. Alternatively, the second sample rack may be used to place samples requiring electrolyte detection and biochemical testing. The specimen analyzer according to claim 1, characterized in that the second specimen rack is transferred from the first rail (21) to the second rail (22) and on which specimens requiring electrolyte detection are placed.
10. A method for collecting a specimen, The first sampling zone is located on the first rail (21), and the second sampling zone is located on the second rail (22). In the first sampling zone, the first sample addition mechanism transfers the sample from the sample container supported on the first sample rack to the reaction container placed on the reaction disk (10). In the second sampling zone, the second sample addition mechanism transfers the sample from the sample containers supported on the second sample rack to the detection containers placed on the electrolyte detection mechanism (30). The first rail (21) includes a first supply end (212) and a first discharge end (213) arranged opposite each other, the second rail (22) includes an inlet / outlet end (221), and the third rail (24) includes a third supply end (241) and a third discharge end (242) arranged opposite each other. The first discharge end (213), the input / output end (221), and the third supply end (241) are located at the same end of the sample analyzer, while the first supply end (212) and the third discharge end (242) are both located at the other end opposite to the aforementioned end. The first sample rack or the second sample rack enters the sample analyzer via the first supply end (212). Before transferring the sample from the sample container supported on the second sample rack into the detection container placed on the electrolyte detection mechanism (30), the sample collection method further includes the step of transferring the second sample rack to the second sampling zone. The second sample rack passes through the first sampling zone in the process of being transferred to the second sampling zone. The second sample rack is transferred from the first discharge end (213) of the first rail (21) to the sample rack transfer mechanism (23), and further transferred from the sample rack transfer mechanism (23) to the pre-entry discharge end (221) of the second rail (22). After the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container, the second sample rack is transferred from the second sampling zone to the input / output end (221) and from the input / output end (221) to the sample rack transfer mechanism (23), the second sample rack is transferred from the sample rack transfer mechanism (23) to the third supply end (241) of the third rail (24), and the second sample rack is separated from the sample analyzer via the third discharge end (242) of the third rail (24). A method for collecting samples for a sample analyzer, characterized in that, after the first sample addition mechanism transfers a sample from a sample container supported on the first sample rack to a reaction container placed on the reaction disk (10), the sample collection method further includes the steps of: the first sample rack being transferred from the first discharge end (213) of the first rail (21) to the sample rack transfer mechanism (23); the first sample rack being transferred from the sample rack transfer mechanism (23) to the third supply end (241) of the third rail (24); and the first sample rack being moved away from the sample analyzer via the third discharge end (242) of the third rail (24).
11. The first sampling zone is located on the first rail (21), and the second sampling zone is located on the second rail (22). The second rail (22) and the first rail (21) are parallel to each other. The method for collecting a sample from a sample analyzer according to claim 10, characterized in that the second sample rack is transferred from the first rail (21) to the sample rack transfer mechanism (23), and then transferred from the sample rack transfer mechanism (23) to the second rail (22).
12. When the second sample rack reaches the first sampling zone, the first sample addition mechanism transfers the sample in the sample container carried on the second sample rack to the reaction vessel. When the second sample rack reaches the second sampling zone, the second sample addition mechanism transfers the sample from the sample container carried on the second sample rack to the detection container, and here, after the first sample addition mechanism transfers the sample from the sample container carried on the second sample rack to the reaction container, the second sample rack moves from the first sampling zone to the first discharge end (213) of the first rail (21), and then transfers from the first discharge end (213) to the sample rack transfer mechanism (23). The specimen rack transfer mechanism (23) transfers the second specimen rack to the inlet / outlet end (221) of the second rail (22). The second sample rack extends from the input / output end (221) to the second sampling zone, and the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container placed on the electrolyte detection mechanism (30). The method for collecting a sample in a sample analyzer according to claim 11, characterized in that, after the second sample addition mechanism transfers the sample from the sample container supported on the second sample rack into the detection container, the second sample rack moves from the second sampling zone to the inlet / outlet end (221) and then moves from the inlet / outlet end (221) to the sample rack transfer mechanism (23).
13. The method for collecting samples in a sample analyzer according to claim 10, characterized in that, in the process of transferring a sample from a sample container supported on the second sample rack to the detection container, the second sample rack is placed in the second sampling zone, and the second sample addition mechanism can move into a different sample container supported on the second sample rack to collect a sample.
14. In the process by which the first sample addition mechanism transfers samples from sample containers supported on the first sample rack to the reaction vessel, the sample containers supported on the first sample rack sequentially pass through the common sampling point (211), and the first sample addition mechanism transfers samples from the sample containers located at the common sampling point (211) to the reaction vessel. Here, the first sample addition mechanism includes a first sample addition arm (411) and a second sample addition arm (412), which are independent of each other. The reaction disc (10) includes an outer reaction tray (11) and an inner reaction tray (12) provided inside the outer reaction tray (11). In the process by which the first sample addition mechanism transfers a sample from a sample container supported on the first sample rack to a reaction vessel supported on the reaction disk (10), the first sample addition arm (411) aspirates a first sample from one of the sample containers located at the common sampling point (211) and transfers the first sample into the reaction vessel placed on the reaction inner tray (12). In the process of transferring the first sample to the reaction vessel placed on the reaction inner tray (12) by the first sample addition arm (411), the second sample addition arm (412) aspirates the first sample from one of the sample containers located at the common sampling point (211) and transfers the first sample into the reaction vessel placed on the reaction outer tray (11). Alternatively, the method for collecting a sample in a sample analyzer according to claim 10, characterized in that, during the process in which the first sample is transferred by the first sample adding arm (411) to the reaction vessel placed on the reaction inner tray (12), the second sample adding arm (412) aspirates a second sample from another sample container located at the common sampling point (211) and transfers the second sample into the reaction vessel placed on the reaction outer tray (11).