Pneumatic siphon valves and reaction chambers for sample analysis.

The siphon valve structure and centrifugal device address inefficiencies in healthcare diagnostics by decoupling pressure from radial position and enabling compact, reusable fluid handling, enhancing rapid testing capabilities.

BR112025019115A2Pending Publication Date: 2026-07-14VITAL BIOSCIENCES INC
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Patent Information

Authority / Receiving Office
BR · BR
Patent Type
Applications
Current Assignee / Owner
VITAL BIOSCIENCES INC
Filing Date
2024-03-09
Publication Date
2026-07-14

AI Technical Summary

Technical Problem

Current diagnostic processes in healthcare are disconnected from care delivery, leading to inefficiencies and poor patient outcomes, especially in rural areas, and existing centrifugal microfluidic devices lack a comprehensive, rapid testing solution due to unsatisfactory valve designs that depend on radial position and require space-consuming flushing steps.

Method used

A siphon valve structure that decouples pressure change from radial position, occupies less space, and is reusable, combined with a centrifugal device that retains and homogenizes magnetic particles for efficient sample analysis.

Benefits of technology

Enables compact, efficient, and reusable fluid handling in centrifugal microfluidics, allowing for rapid, comprehensive test results without the need for external magnetic fields, reducing waste and improving healthcare delivery.

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Abstract

A rotatable device includes a vent port, a siphon and a ballast chamber. The siphon has a crest positioned radially outwards of the vent port with respect to the rotational axis. The ballast chamber has a first outlet connected to the vent port and a second outlet connected to an inlet of the siphon. The first outlet of the ballast chamber is positioned radially inwards of the second outlet of the ballast chamber and radially outwards of the crest of the siphon with respect to the rotational axis. As such, the first outlet of the ballast chamber divides the ballast chamber into an unvented ballast portion radially inwards of the first outlet and a vented ballast portion radially outwards of the first outlet, and thus decouples the pressure change inside the ballast chamber from the radial position of the siphon inlet at the ballast chamber.
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