Enzyme-containing detergent compositions

Abstract

A method for enhancing the enzyme-containing detergent properties of an enzyme-containing detergent composition is disclosed, the method comprising the step of adding an amphoteric polysaccharide to the composition.

Description

[0001] This invention relates to an enzyme-containing detergent composition that can be used in a variety of applications, particularly in personal care and household care detergents; and a method for enhancing the enzyme-containing detergent composition by means of adding an amphoteric polysaccharide to the composition. Background Technology

[0002] The following discussion of prior art is provided to place the invention within a suitable technical context and to allow its advantages to be more fully understood. However, it should be understood that any discussion of prior art throughout the specification should not be construed as an explicit or implicit admission that such prior art is widely known or forms part of common general knowledge in the art.

[0003] The use of enzymes in detergent formulations is now common in developed countries, with more than half of all currently available detergents containing enzymes.

[0004] Dirt can appear in many forms and includes proteins, starches, and lipids. Furthermore, starched clothes must be starch-free. Using detergent in water at high temperatures and with vigorous mixing can remove most types of dirt, but heating the water is expensive, and prolonged mixing or beating will shorten the lifespan of clothes and other materials. The use of enzymes allows for lower temperatures and typically requires shorter agitation cycles after an initial soaking period. Generally, enzyme-containing detergents are far more effective at removing proteins from clothes stained with blood, milk, sweat, or grass than enzyme-free detergents.

[0005] In the field of liquid detergent formulations, there is a constant need to deliver improved cleaning technologies, especially as consumers move toward more eco-friendly processes, such as reducing water use per wash cycle. Various methods have been used to improve catalytic efficiency and / or better stability to temperature, oxidants, and different washing conditions, significantly through site-directed and / or randomly mutagenic enzymes, such as proteases.

[0006] Despite the fact that numerous patent publications, reviews, and articles have been published on enzymes from various microorganisms, such as low-temperature alkaline proteases from actinomycetes (Nocardiopsis dassonvillei) and fungi (Paecilomyces marquandii), there remains a significant need for alternative enzyme-containing detergent compositions that are suitable for and effective in modifying, degrading, and removing materials with diverse stains, particularly in low or medium temperature ranges, and stable in the presence of detergents with highly variable properties. Stability during storage is also crucial due to the autocatalytic properties of some enzymes.

[0007] Therefore, formulators need to provide detergent formulations that deliver excellent enzymatic cleaning properties during and after the formulation's storage, and provide excellent dissolution and release of active ingredients during the wash cycle. Summary of the Invention

[0008] This invention provides a method for enhancing the detergent properties of enzyme-containing compositions, which effectively modifies, degrades, and removes materials with various stains, particularly in low or medium temperature ranges, and delivers excellent enzymatic cleaning properties. This invention also allows for the production of enzyme-containing compositions that are cost-effectively processed downstream.

[0009] Therefore, the present invention relates to a method for enhancing the enzyme-containing detergent properties of an enzyme-containing detergent composition, the method comprising the step of adding an amphoteric polysaccharide to the composition.

[0010] The present invention also relates to the use of amphoteric polysaccharides in enhancing the enzyme-detergent properties of enzyme-containing detergent compositions.

[0011] The present invention further relates to a composition comprising at least:

[0012] -Detergent,

[0013] - Enzymes with detergent properties, and

[0014] - Amphoteric polysaccharides that significantly enhance the detergent properties of this enzyme.

[0015] The methods and compositions described herein can be used in a variety of applications, particularly in laundry, fabric care, shower gels, hand soaps, shampoos, hard surface cleaners, and kitchenware detergents.

[0016] The method of the present invention significantly allows for the removal of protein, starch, and grease or oil stains from fabrics, keratinous materials (such as hair and skin), hard surfaces, kitchenware and glassware, floors and walls.

[0017] In the context of this invention, the detergent properties of an enzyme refer specifically to its stain removal performance, which enables the enzyme to hydrolyze or remove stains, such as protein stains, particularly insoluble substances or materials on a substrate. Typically, the washing performance under different conditions and exposure to different treatments is measured as “stain removal efficiency” or “stain removal effect” or “degree of cleaning properties,” meaning a visible and measurable increase in lightness or color change of the stained material (e.g., in a small, artificially soiled sample or test fabric). Lightness or color change values ​​can be measured, for example, by measuring color as a reflectance value using L*a*b* color space coordinates with a spectrophotometer. The fading or removal of stains, indicating enzyme performance (stain removal efficiency), is calculated, for example, as ΔL*, which means the lightness value L* of the enzyme-treated fabric minus the lightness value L* of the fabric treated with a buffer or detergent solution without the enzyme (enzyme blank or control).

[0018] In the context of this invention, the method for enhancing the detergent properties of an enzyme refers to an improvement in detergent performance, meaning that the enzyme performs better or significantly better in the presence of the amphoteric polysaccharide than it does in the absence of the amphoteric polysaccharide.

[0019] The term "detergent" is used to refer to a substance or material intended to aid in cleaning or possessing cleaning properties. The term "detergent power" indicates the presence or extent of cleaning properties. The degree of cleaning properties can be tested on various stained substrates or stains or stain mixtures bonded to solid, water-insoluble carriers (such as textile fibers or glass). Typical staining materials include blood, milk, ink, eggs, grass, and sauces. Stain mixtures used for testing purposes are commercially available.

[0020] Other features, details and advantages of the invention will become more apparent upon reading the following description.

[0021] definition

[0022] For convenience, certain terms used in the specification and examples are compiled herein before further description of this disclosure. These definitions should be read and understood by those skilled in the art in accordance with the remainder of this disclosure. The terms used herein have meanings that are generally accepted and known to those skilled in the art; however, for convenience and completeness, specific terms and their meanings are listed below.

[0023] The use of the articles "a / an" and "the" refers to one or more (i.e., at least one) of the grammatical objects.

[0024] The term “and / or” includes the meaning of “and”, “or”, and also includes all other possible combinations of the elements associated with the term.

[0025] The terms “comprise” and “comprising” are used in a sense of inclusion and openness, meaning that they may include additional elements. Throughout this specification, unless the context otherwise specifies, the words “comprise” and variations such as “comprises” and “comprising” should be understood to mean including the stated element or step or group of elements or steps, but not excluding any other element or step or group of elements or steps.

[0026] Ratios, concentrations, quantities, and other numerical data may be expressed in range form here. It should be understood that this range form is used only for convenience and brevity and should be interpreted flexibly to include not only the values ​​explicitly stated as the limits of the range, but also all individual values ​​or subranges encompassed within that range, just as each individual value and subrange is explicitly stated. For example, a temperature range of approximately 120°C to approximately 150°C should be understood to include not only the explicitly stated limits of approximately 120°C to approximately 150°C, but also subranges such as 125°C to 145°C, 130°C to 150°C, etc., and individual quantities within the specified range, including small quantities such as 122.2°C, 140.6°C, and 141.3°C.

[0027] The term “between” should be understood to include the limit value.

[0028] It should be noted that, for the sake of continuity in this specification, unless otherwise indicated, limit values ​​are included within a range of given values. It should be noted that when specifying any concentration range, any specific upper limit concentration can be associated with any specific lower limit concentration.

[0029] As used herein, the term "hydrocarbon group" refers to a group consisting primarily of carbon and hydrogen atoms, which may be saturated or unsaturated, straight-chain, branched or cyclic, aliphatic or aromatic. The term "hydrocarbon group" as used in the specification and claims describes a group based on a hydrocarbon having the stated number of carbon atoms and may be a pure hydrocarbon group but may also have substituents. The hydrocarbon group of the present invention may be alkyl, alkenyl, alkynyl, aryl, alkylaryl, aralkyl, heterocyclic, and / or alkyl heterocyclic.

[0030] The hydrocarbon group of the present invention can be alkyl, alkenyl, alkynyl, aryl, alkylaryl, aralkyl, heterocyclic group, and / or alkyl heterocyclic group.

[0031] As used herein, the term "(C)" refers to an organic group. n -C m ")", where n and m are integers, indicating that the group can contain from n to m carbon atoms per group.

[0032] As used herein, "alkyl" should be interpreted in its ordinary sense. Alkyl groups include saturated hydrocarbons having one or more carbon atoms, including straight-chain alkyl groups such as methyl, ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, nonyl, and decyl; cyclic alkyl groups (or "cycloalkyl" or "alicyclic" or "carbocyclic" groups), such as cyclopropyl, cyclopentyl, cyclohexyl, cycloheptyl, and cyclooctyl; branched alkyl groups such as isopropyl, tert-butyl, sec-butyl, and isobutyl; and alkyl-substituted alkyl groups, such as alkyl-substituted cycloalkyl groups and cycloalkyl-substituted alkyl groups. The term "aliphatic group" includes organic parts characterized as straight-chain or branched, typically having between 1 and 22 carbon atoms. In complex structures, these chains can be branched, bridged, or cross-linked. Aliphatic groups include alkyl, alkenyl, and ynyl groups.

[0033] As used herein, "alkenyl" or "alkenyl" refers to an aliphatic hydrocarbon group, which may be straight-chain or branched and contains at least one carbon-carbon double bond. Examples of alkenyl groups include, but are not limited to, vinyl, propenyl, n-butenyl, isobutenyl, 3-methylbut-2-enyl, n-pentenyl, heptenyl, octenyl, decenyl, etc. The term "alkynyl" refers to a straight-chain or branched hydrocarbon group having at least one carbon-carbon triple bond, such as ethynyl.

[0034] The term "aryl" includes unsaturated and aromatic cyclic hydrocarbons as well as unsaturated and aromatic heterocycles (containing one or more rings). Aryl groups can also be fused or bridged with alicyclic rings or non-aromatic heterocycles to form polycyclic compounds, such as tetrahydronaphthalene. "Arylene" is a divalent analogue of an aryl group.

[0035] The term "heterocyclic group" includes closed-ring structures similar to carbocyclic groups, wherein one or more carbon atoms in the ring are elements other than carbon, such as nitrogen, sulfur, or oxygen. Heterocyclic groups can be saturated or unsaturated. Furthermore, heterocyclic groups, such as pyrrole, pyridinyl, isoquinolinyl, quinolinyl, purine, and furanyl, can have aromatic characteristics; in this case, they can be referred to as "heteroaryl" or "heteroaromatic" groups.

[0036] It should be noted that a chemical part that forms part of a larger compound may be described here using the name that usually corresponds to it, when it exists as a single molecule or the name that usually corresponds to its group. For example, the terms "pyridine" and "pyridyl" have the same meaning when used to describe a part attached to another chemical part. Detailed Implementation

[0037] Those skilled in the art will appreciate that variations and modifications have been made to this disclosure in addition to those specifically described. It should be understood that this disclosure includes all such variations and modifications. This disclosure also includes all such steps, features, compositions, and compounds, as well as any one or more of any combination of such steps or features, individually or collectively mentioned or indicated in this specification.

[0038] Amphoteric polysaccharides

[0039] Suitable, non-limiting examples of polysaccharides include, for example, galactomannan, chitosan, pectin, alginate, hyaluronic acid, agar, xanthan gum, dextrin, starch, amylose, amylopectin, alternan, extracellular polysaccharides, mutans, dextran, pullulan, fructan, gum arabic, carrageenan, glycogen, glycosaminoglycans, cell wall material, xyloglucan, and bacterial capsular polysaccharides.

[0040] In some embodiments, the polysaccharide includes, for example, galactomannan such as guar gum, including guar gum derivatives; xanthan gum; polyfructose and fructose; starch, including starch derivatives such as amylopectin; xyloglucan such as tamarind gum and tamarind gum derivatives such as hydroxypropyl tamarind gum; and cellulose, including cellulose derivatives such as methylcellulose, ethylcellulose, carboxymethylcellulose, hydroxyethylcellulose, cellulose acetate, cellulose acetate butyrate, and cellulose acetate propionate.

[0041] Galactomannan is a polysaccharide primarily composed of the monosaccharides mannose and galactose. The mannose elements form chains of hundreds of (1,4)-β-D-galactopyranosyl residues, depending on the plant source, with 1,6-linked β-D-galactopyranosyl residues at varying distances. Naturally occurring galactomannans are available from numerous sources, including guar gum, guar split, locust bean gum, tara gum, regalangal, and cassia gum. Furthermore, galactomannans can be obtained through classical synthetic routes or through chemical modification of naturally occurring galactomannans.

[0042] Guar gum is specifically the mucilage found in the seeds of the legume *Cyamopsis tetragonolobus*. The water-soluble portion (85%) is referred to as "guar sugar," and it consists of a straight chain of (1,4)-β-D-mannopyranosyl units linked by (1,6) bonds to α-D-galactopyranosyl units. The ratio of D-galactose to D-mannose in guar sugar is approximately 1:2. Guar gum typically has a weight-average molecular weight between 2,000,000 and 5,000,000 Daltons. Guar gum with decreasing molecular weights, such as from about 2,000 to about 2,500,000 Daltons, is also known.

[0043] Guar seeds consist of a pair of tough, non-brittle endosperm portions (hereinafter referred to as "guar flakes") with a brittle embryo (germinator) sandwiched between them. After dehulling, the seeds are split open, the germ (43%-47% of the seed) is removed by sieving, and the split seeds are ground. These ground, split seeds have been reported to contain approximately 78%-82% galactomannan polysaccharides, as well as small amounts of protein material, inorganic non-surfactant salts, water-insoluble gum, and cell membranes, along with some residual seed coat and embryo.

[0044] Carob gum, or locust bean gum, is the refined endosperm of the seeds of the carob tree (Ceratonia siliqua). For this type of gum, the ratio of galactose to mannose is approximately 1:4. Carob gum is commercially available.

[0045] Tara gum is a refined seed gum derived from the tara tree. The ratio of galactose to mannose is approximately 1:3. Tara gum is also commercially available.

[0046] Xanthan gum of interest is both xanthan gum and xanthan gum gel. Xanthan gum is a polysaccharide gum produced by Xanthomonas campestris and contains D-glucose, D-mannose, and D-glucuronic acid as the main hexose units, as well as pyruvate, which is partially acetylated.

[0047] Fructose is a polyfructose consisting of 5-membered rings linked by β-2,6 bonds and branched by β-2,1 bonds. Fructose exhibits a glass transition temperature of 138 °C and is available in particulate form. At molecular weights of 1-2 million, the diameter of closely packed spherical particles is approximately 85 nm.

[0048] Tamarind (Tamahndus indica) is a tall, evergreen legume native to the tropics. Tamarind gum (tamarind powder or tamarind kernel powder) (xyglucan polysaccharide) is obtained by extracting and purifying seed powder (obtained by grinding tamarind seeds). The polysaccharide molecule of tamarind gum consists of a linear backbone of polydextrose molecules with xylose and galactoxylose substituents.

[0049] In the context of this invention, the term "amphoteric polysaccharide" means a polysaccharide derivative comprising at least one anionic substituent and at least one cationic substituent, as well as a polysaccharide that can be made amphoteric, for example, comprising quaternizable amine groups and / or acid groups.

[0050] Amphoteric polysaccharides can be specifically selected from:

[0051] The grafted polysaccharide has units A and B, where A represents a cationic unit derived from a monomeric or polymeric group containing at least one nitrogen atom belonging to a primary, secondary, tertiary, or quaternary amine functional group, and B represents an anionic unit derived from a monomeric or polymeric group containing one or more carboxylic acid, phosphoric acid, phosphonic acid, sulfate, or sulfonic acid functional groups.

[0052] Grafted polysaccharides have one or more units C, where C represents a unit derived from a monomeric or polymeric group containing at least one zwitterionic group or a carboxybetaine or sulfobetaine;

[0053] A polysaccharide grafted with one or more units D, wherein D represents a unit derived from a monomeric or polymeric group containing at least one anionic group and at least one cationic group, the anionic group being derived from a monomeric or polymeric group containing one or more functional groups of carboxylic acid, phosphoric acid, phosphonic acid, sulfate or sulfonic acid, and the cationic group containing primary, secondary, tertiary or quaternary amine functional groups.

[0054] Amphoteric polysaccharides may additionally contain nonionic functional groups, which can be selected from:

[0055] -Hydroxyl groups, such as hydroxyethylated groups and hydroxypropylated groups

[0056] -Hydroxyalkyl, such as hydroxymethyl hydroxyethyl, hydroxypropyl or hydroxybutyl.

[0057] Methods for producing amphoteric polysaccharides are known. In particular, methods for producing derivatives of guar gum are generally known. Typically, guar gum is reacted with one or more derivatizing agents under suitable reaction conditions to produce guar gum polysaccharides with desired substituents. Suitable derivatizing agents are commercially available and typically contain reactive functional groups, such as epoxy groups, chloroethanol groups, or olefinically unsaturated groups, and at least one other substituent per molecule, such as cationic, nonionic, or anionic substituents, or precursors of such substituents, wherein the substituents can be linked to the reactive functional groups of the derivatizing agent via divalent linking groups (such as alkylene or oxoalkylene groups). Suitable cationic substituents include primary, secondary, or tertiary amine groups, or quaternary ammonium, thionium, or phosphonium groups. Suitable nonionic substituents include hydroxyalkyl groups, such as hydroxypropyl groups. Suitable anionic groups include carboxylalkyl groups, such as carboxymethyl groups. These cationic, nonionic, and / or anionic substituents can be introduced into the polysaccharide chain through a series of reactions or by simultaneous reaction with appropriate derivatizing reagents.

[0058] To introduce substituents into polysaccharide polymers, the polymers (e.g., guar gum) can be treated with crosslinking agents. For example, borax (sodium tetraborate) is commonly used as a processing aid in the reaction steps of the water-splits process to partially crosslink the surface of these guar gum sheets and thereby reduce the amount of water absorbed by these guar gum sheets during processing. Other crosslinking agents, such as glyoxal or titanate compounds, are known.

[0059] According to each embodiment of the invention, the amphoteric polysaccharide is preferably a polysaccharide grafted with cationic and anionic units, wherein the cationic units are derived from monomeric or polymeric groups containing at least one nitrogen atom belonging to a primary, secondary, tertiary, or quaternary amine functional group, and the anionic units are derived from monomeric or polymeric groups containing one or more carboxylic acid, phosphoric acid, phosphonic acid, sulfate, or sulfonic acid functional groups, and the amphoteric polysaccharide optionally contains nonionic functional groups.

[0060] Advantageously, the amphoteric polysaccharides are amphoteric galactomannans, particularly amphoteric guar gum. Advantageously, the amphoteric polysaccharides are selected from:

[0061] Carboxymethyl hydroxypropyl trimethylammonium chloride galactomannan, especially carboxymethyl hydroxypropyl trimethylammonium chloride galactomannan guar gum;

[0062] Carboxymethyl hydroxypropyl hydroxypropyl trimethylammonium chloride galactomannan, especially carboxymethyl hydroxypropyl hydroxypropyl trimethylammonium chloride guar gum.

[0063] As used herein, the term "degree of substitution" (DS) with respect to a given type of derivatized group and a given polysaccharide polymer refers to the average number of such derivatized groups attached to each monomer unit of the polysaccharide polymer. In some embodiments, amphoteric polysaccharides exhibit a total degree of substitution ("DST") from about 0.001 to about 3.0, wherein:

[0064] DST is DS with cationic substituents (“DS”). 阳离子 DS with nonionic substituents (“DS”) 非离子 DS with anionic substituents (“DS”) 阴离子 The sum of () can be measured, for example, by 1H-NMR. 阳离子 DS 非离子 and DS 阴离子 .

[0065] In the amphoteric polysaccharide of the present invention,

[0066] -DS 阳离子Preferably, the stoichiometry is from 0.001 to 3, more typically from about 0.001 to about 1.0, and even more typically from about 0.001 to about 0.5, particularly from about 0.001 to about 0.1. Preferably, the DS cation is equal to 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, and 0.1, or any range including these values.

[0067] -DS 阴离子 It can be from about 0.01 to about 3.0, more typically from about 0.001 to about 1.0, and even more typically from about 0.1 to about 0.6, particularly from about 0.01 to about 0.2. Preferably, DS 阴离子 It equals 0.1, 0.12, 0.14, 0.16, 0.18, and 0.2, or any range between these values.

[0068] -DS 非离子 It can range from about 0 to about 3.0, more typically from about 0.001 to about 2.5, and even more typically from about 0.001 to about 1.0.

[0069] As used herein, the term "molar degree of substitution" or "MS" refers to the number of moles of the derivative groups of the monosaccharide monomer per mole of the polysaccharide. The molar degree of substitution can be determined by the Zeisel-GC method. The molar degree of substitution used in this invention is typically in the range of about 0.001 to about 3.

[0070] Preferably, the amphoteric polysaccharide of the present invention has a DS greater than or equal to its DS. 阳离子 DS value 阴离子 Value. More preferably, amphoteric polysaccharides have a value greater than their DS. 阳离子 DS value 阴离子 In other words, the amphoteric polysaccharide exhibits a net negative charge.

[0071] Preferably, the DS of amphoteric polysaccharides 阴离子 With DS 阳离子 The ratio (absolute value) between them is from 1:1 to 10:1, more preferably from 1:1 to 5:1.

[0072] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have a DS greater than or equal to their DS values. 阳离子 DS value 阴离子 Value, and DS 阳离子 It is in the range of 0.01 to 1.0, more preferably from 0.01 to 0.5, and even more preferably from 0.01 to 0.1.

[0073] Amphoteric polysaccharides, such as amphoteric galactomannan, preferably have an average molecular weight (Mw) between 100,000 Daltons and 3,500,000 Daltons, more preferably between 500,000 Daltons and 2,500,000 Daltons, and even more preferably between 1,000,000 Daltons and 2,500,000 Daltons.

[0074] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have an average molecular weight from 1,000,000 Daltons to 2,500,000 Daltons and a DS ratio of 0.001 to 0.1. 阳离子 .

[0075] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have an average molecular weight from 1,000,000 Daltons to 2,500,000 Daltons and a DS ratio of 0.001 to 0.1. 阳离子 And DS from 0.01 to 0.2 阴离子 .

[0076] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have an average molecular weight from 1,000,000 Daltons to 2,500,000 Daltons, and the amphoteric polysaccharides have a molecular weight greater than their DS. 阳离子 DS value 阴离子 value.

[0077] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have an average molecular weight from 1,000,000 Daltons to 2,500,000 Daltons and a DS ratio of 0.001 to 0.1. 阳离子 Furthermore, amphoteric polysaccharides have a higher DS value than their DS content. 阳离子 DS value 阴离子 value.

[0078] In some embodiments, amphoteric polysaccharides such as amphoteric galactomannan have an average molecular weight from 1,000,000 Daltons to 2,500,000 Daltons and a DS ratio of 0.001 to 0.1. 阳离子 And DS from 0.01 to 0.2 阴离子 Among them, amphoteric polysaccharides have a higher DS value than their DS content. 阳离子 DS value 阴离子 value.

[0079] Based on the total weight of the detergent composition, the amphoteric polysaccharide may be present in an amount from 0.01 to 5 wt%, preferably 0.1 to 1 wt%, more preferably from 0.3 to 0.8 wt%.

[0080] Detergent

[0081] Detergent compositions may contain one or more surfactants as active detergent ingredients, which may be anionic and / or cationic and / or nonionic and / or semipolar and / or zwitterionic, or mixtures thereof.

[0082] In some embodiments, the detergent composition comprises a mixture of one or more nonionic surfactants and one or more anionic surfactants. The one or more surfactants are typically present at levels ranging from about 0.1% to 60% by weight, such as about 1% to about 40%, or about 1% to about 20%, or about 3% to about 10%. The one or more surfactants are selected based on the desired cleaning application, and the one or more surfactants may include any conventional one or more surfactants known in the art. Preferably, the active ingredient in the detergent is an anionic surfactant.

[0083] When included in a detergent composition, the detergent composition may typically contain from about 1% to about 40% by weight of anionic surfactant, such as from about 5% to about 30%, including from about 5% to about 15%, or from about 15% to about 20%, or from about 20% to about 25% of anionic surfactant.

[0084] Non-limiting examples of anionic surfactants include sulfates and sulfonates, particularly linear alkylbenzene sulfonates (LAS), isomers of LAS, branched alkylbenzene sulfonates (BABS), phenyl alkyl sulfonates, α-olefin sulfonates (AOS), olefin sulfonates, chain olefin sulfonates, alkyl-2,3-dimethylbis(sulfate), hydroxyalkyl sulfonates and disulfonates, alkyl sulfates (AS) such as sodium dodecyl sulfate (SDS), fatty alcohol sulfates (FAS), primary alcohol sulfates (PAS), and alcohol ethers. Sulfates (AES or AEOS or FES, also known as alcohol ethoxy sulfates or fatty alcohol ether sulfates), secondary alkyl sulfonates (SAS), paraffin sulfonates (PS), ester sulfonates, sulfonated fatty acid glycerides, α-sulfonated fatty acid methyl esters (α-SFMe or SES) (including methyl sulfonate (MES)), alkyl- or alkenyl succinic acids, dodecenyl / tetradecenyl succinic acids (DTSA), fatty acid derivatives of amino acids, diesters and monoesters or fatty acid salts (soaps) of sulfosuccinic acids, and combinations thereof.

[0085] Anionic surfactants can include alkyl ether sulfates, soaps, fatty acid ester sulfonates, alkylamide sulfates, alkylbenzene sulfonates, sulfosuccinates, primary alkyl sulfates, olefin sulfonates, alkane sulfonates, and organophosphates. Preferred anionic surfactants are alkali metal and alkaline earth metal salts of the following: fatty acid carboxylates, fatty alcohol sulfates, preferably primary alkyl sulfates, more preferably ethoxylated, such as alkyl ether sulfates; alkylbenzene sulfonates, alkyl ester fatty acid sulfonates, especially methyl ester fatty acid sulfonates, and mixtures thereof.

[0086] The specific anionic surfactants that can be mentioned are:

[0087] - Alkyl ester sulfonates having the formula R'-CH(SO3M)-COOR”, where R' represents C8-C 20 And C is preferred 10 -C 16 The alkyl group, R”, represents a C1-C6 alkyl group, preferably a C1-C3 alkyl group, and M represents an alkali metal (sodium, potassium, or lithium) cation, a substituted or unsubstituted ammonium (methyl-, dimethyl-, trimethyl-, or tetramethylammonium, dimethylpiperidinium, etc.) or an alkanolamine derivative (monoethanolamine, diethanolamine, triethanolamine, etc.). Most notably, the group R’ is C… 14 -C 16 Methyl ester sulfonate;

[0088] - Alkyl sulfates having the formula R'OSO3M, where R' represents C5-C 24 And C is preferred 10 -C 18 Alkyl or hydroxyalkyl groups, M representing a hydrogen atom or a cation as defined above, and also ethoxylated (EO) and / or propoxylated (PO) derivatives thereof, containing an average of 0.5 to 30, and preferably 0.5 to 10 EO and / or PO units;

[0089] - Alkylamide sulfates having the formula R'CONHR”OSO3M, where R' represents C2-C 22 And C6-C is preferred. 20 Alkyl groups, where R” represents a C2-C3 alkyl group, M represents a hydrogen atom or a cation as defined above, and also its ethoxylated (EO) and / or propoxylated (PO) derivatives, containing an average of 0.5 to 60 EO and / or PO units;

[0090] -Saturated or unsaturated C8-C 24 And C is preferred 14 -C 20 Fatty acid salts, C9-C 20 Alkylbenzene sulfonates, primary or secondary C8-C 22Alkyl sulfonates, alkyl glycerol sulfonates, sulfonated polycarboxylic acids, paraffin sulfonates, N-acyl-N-alkyl taurine, alkyl phosphates, hydroxyethyl sulfonates, alkyl succinates, alkyl sulfosuccinates, sulfosuccinate monoesters or diesters, N-acyl sarcosinates, alkyl glycoside sulfates, polyethoxycarboxylates; the cation is an alkali metal (sodium, potassium, or lithium), substituted or unsubstituted ammonium residues (methyl-, dimethyl-, trimethyl- or tetramethylammonium, dimethylpiperidinium, etc.) or alkanolamine derivatives (monoethanolamine, diethanolamine, triethanolamine, etc.).

[0091] When included in a detergent composition, the detergent composition may typically contain, by weight, from about 0.1% to about 20%, for example from about 0.1% to about 10%, particularly from about 0.1% to about 5%, from about 0.1% to about 2% of a cationic surfactant.

[0092] Various quaternary ammonium cationic surfactants can be used as the cationic surfactants of this invention; however, acyclic quaternary surfactants are preferred. For example, useful acyclic synthetic quaternary surfactants include linear alkyl, branched alkyl, hydroxyalkyl, oleylalkyl, acyloxyalkyl, diamidoamine, or diester quaternary ammonium compounds. Preferred quaternary surfactants used in this invention are waxy solids or highly viscous at ambient temperature, allowing the material to be melted and thermally applied to a substrate, and these can include conventional tetraalkyl materials or ester quaternary ammonium salts, or a combination of both. Preferably, the quaternary ammonium cationic surfactant is a fabric softener. Also preferably, the quaternary ammonium cationic surfactant is an antistatic agent.

[0093] Non-limiting examples of cationic surfactants include alkyl dimethyl ethanolamine quaternary ammonium salt (ADMEAQ), hexadecyl trimethyl ammonium bromide (CTAB), dimethyl distearate ammonium chloride (DSDMAC), and alkyl benzyl dimethyl ammonium, alkyl quaternary ammonium compounds, alkoxylated quaternary ammonium (AQA) compounds, ester quaternary ammonium salts, and combinations thereof.

[0094] When included in a detergent composition, the detergent composition may typically contain from about 0.2% to about 40% by weight, for example from about 0.5% to about 30%, particularly from about 1% to about 20%, from about 3% to about 10%, such as from about 3% to about 5%, from about 8% to about 12%, or from about 10% to about 12% of a nonionic surfactant. Non-limiting examples of nonionic surfactants include alcohol ethoxylates (AE or AEO), alcohol propoxylates, propoxylated fatty alcohols (PFA), alkoxylated fatty acid alkyl esters (such as ethoxylated and / or propoxylated fatty acid alkyl esters), alkylphenol ethoxylates (APE), nonylphenol ethoxylates (NPE), alkyl polysaccharides (APG), alkoxylated amines, fatty acid monoethanolamides (FAM), fatty acid diethanolamides (FADA), ethoxylated fatty acid monoethanolamides (EFAM), propoxylated fatty acid monoethanolamides (PFAM), polyhydroxyalkyl fatty acid amides, or / V-acyl / V-alkyl derivatives of glucosamine (glucosamide GA, or fatty acid glucosamide FAGA), as well as products available under the trade names SPAN and TWEEN, and combinations thereof.

[0095] When included in a detergent composition, the detergent composition may typically contain from about 0% to about 20% by weight of a semi-polar surfactant. Non-limiting examples of semi-polar surfactants include amine oxides (AOs), such as alkyl dimethylamine oxides, / V-(cocoylalkyl)- / V, / V-dimethylamine oxides, and N-(tallow-alkyl)- / V, / V-bis(2-hydroxyethyl)amine oxides, and combinations thereof.

[0096] When included in a detergent composition, the detergent composition may typically contain from about 0% to about 20% by weight of an amphoteric surfactant. Non-limiting examples of amphoteric surfactants include betaines, such as alkyl dimethyl betaine, sulfobetaine, and combinations thereof.

[0097] enzymes

[0098] According to the present invention, the detergent composition contains an enzyme. The enzyme plays two main roles in the detergent composition: stain removal and providing color and fabric care.

[0099] The enzyme is preferably selected from the group consisting of: hemicellulase, peroxidase, protease, cellulase, xylanase, lipase, phospholipase, esterase, keratinase, pectinase, keratinase, reductase, oxidase, phenol oxidase, lipoxygenase, ligninase, amylopectinase, tanninase, pentosanase, malanases, β-glucanase, arabinosidase, hyaluronidase, chondroitinase, laccase, and amylase, or mixtures thereof. Preferably, the enzyme is protease, amylase, and lipase.

[0100] The most commonly used enzymes are proteases (which break down proteins), amylases (which break down starch – a type of carbohydrate), and lipases (which break down fats).

[0101] Preferred enzymes may include proteases. Suitable proteases include proteases of bacterial, fungal, plant, viral, or animal origin, such as plant or microbial proteases. Microbial origin is preferred. This includes chemically modified or protein-engineered mutants. It can be an alkaline protease, such as a serine protease or a metalloproteinase. Serine proteases can be, for example, from the S1 family, such as trypsin, or from the S8 family, such as subtilisin. Metalloproteinases can be, for example, thermophilic bacterial proteases from the M4 family or other metalloproteinases such as those from the M5, M7, or M8 families.

[0102] Suitable proteases include metalloproteinases and serine proteases, including neutral or alkaline microbial serine proteases such as subtilisin (EC 3.4.21.62). In one aspect, such suitable proteases may be of microbial origin. Suitable proteases include chemically or genetically modified mutants of the aforementioned suitable proteases. In one aspect, suitable proteases may be serine proteases such as alkaline microbial proteases and / or trypsin-type proteases. Examples of suitable neutral or alkaline proteases include:

[0103] (a) Substance protease (EC 3.4.21.62), including those derived from the genus Bacillus, such as Bacillus tarda, Bacillus alkalophilus, Bacillus subtilis, Bacillus amyloliquefaciens, Bacillus pumilus, and Bacillus gibsonii.

[0104] (b) Trypsin-type or chymotrypsin-type proteases, such as trypsin (e.g., from pigs or cattle), including Fusarium proteases and chymotrypsin proteases derived from Celumonas.

[0105] (c) Metalloproteinases, including those derived from Bacillus amylolyticus.

[0106] (d) Bacillus subtilis protease derived from Bacillus TY-145 and NCIMB 40339.

[0107] Preferred proteases include those derived from Bacillus giganteus, Bacillus amyloliquefaciens, Bacillus TY-145, or Bacillus tarda.

[0108] Examples of useful proteases are in the following variants, which are described in: WO 92 / 19729, WO 96 / 034946, WO 98 / 20115, WO 98 / 20116, WO 99 / 011768, WO 01 / 44452, WO 03 / 006602, WO 04 / 03186, WO 04 / 041979, and WO 07 / 006305.

[0109] Suitable commercially available proteases include those from Novozymes A / S under the trade name. Liquanase Savinase and Those sold below are from DuPont International Biosciences under the trade name Purafect Purafect Purafect and Those sold under this series are produced by Solvay Enzymes under the brand name... and Those sold below, those available from BASF, namely all BLAP, BLAP R, BLAP X and BLAP F49 from BASF; and KAP (Alkaliophilic Bacillus subtilis protease) from Kao.

[0110] Suitable α-amylases include those of bacterial or fungal origin. This includes chemically or genetically modified mutants (variants). Preferred alkaline α-amylases are derived from strains of the genus *Bacillus*, such as *Bacillus licheniformis*, *Bacillus amyloliquefaciens*, *Bacillus thermophilus*, *Bacillus subtilis*, or other *Bacillus* species such as NCIB 12289, NCIB 12512, NCIB 12513, DSM 9375, DSM 12368, DSMZ 12649, KSM AP1378, KSM K36, or KSM K38.

[0111] Suitable commercially available α-amylases include TERMAMYL STAINZYME and (Novozymes A / S), from Biozym Biotech Trading GmbH (USA) AT 9000 OPTISIZE HT and PURASTAR The S series includes the PREFERENZ S1000 and PREFERENZ S110 (DuPont), and (Kao Corporation). In one respect, suitable amylases include PREFERENZ and STAINZYME And its mixtures.

[0112] In some embodiments, the enzyme may be selected from the group consisting of: lipases, including "first-cycle lipases". In some embodiments, the lipase is a first-washed lipase, preferably a variant of a wild-type lipase from *Thermophilus spp.*

[0113] Preferred lipases will be included in the trade name and Those that are sold below.

[0114] Other preferred enzymes include fungal and microbial endoglucanases (EC 3.2.1.4) exhibiting endoglucanase activity. Suitable endoglucanases are listed under trade names. Carezyme and Sold under (Novozymes A / S).

[0115] Other preferred enzymes include those listed in the trade name. The pectic acid lyase sold under the product name, and the product listed under the product name The mannanases sold below (all from Novozymes A / S), and Preferenz and (DuPont)

[0116] Suitable perhydrolysins catalyze perhydrolysis reactions, which result in the production of peracids from carboxylic acid ester (acyl) substrates in the presence of a peroxide source (e.g., hydrogen peroxide). While many enzymes perform this reaction at low levels, perhydrolysins exhibit high perhydrolysis:hydrolysis ratios, typically greater than 1. Suitable perhydrolysins can be of plant, bacterial, or fungal origin. This includes chemically modified or protein-engineered mutants. Examples of useful perhydrolysins include naturally occurring mycobacterial perhydrolysins or variants thereof. An exemplary enzyme is derived from Mycobacterium smegmatis.

[0117] Suitable oxidases and peroxidases (or oxidoreductases) include various sugar oxidases, laccases, peroxidases, and halogen peroxidases. Suitable peroxidases include those included in the enzyme classification EC 1.11.1.7 as stated by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB), or any fragments derived therefrom exhibiting peroxidase activity. Suitable peroxidases include those of plant, bacterial, or fungal origin. This includes chemically modified or protein-engineered mutants. Examples of useful peroxidases include those from the genus *Coprinus*, such as peroxidases from *Coprinus spp.* and their variants.

[0118] The oxidases according to the invention specifically include any laccase included in enzyme classification EC 1.10.3.2, or any fragment derived therefrom exhibiting laccase activity, or compounds exhibiting similar activity, such as catechol oxidase (EC 1.10.3.1), o-aminophenol oxidase (EC 1.10.3.4), or bilirubin oxidase (EC 1.3.3.5).

[0119] Preferred laccases are microbial enzymes. These enzymes can be derived from plants, bacteria, or fungi (including filamentous fungi and yeasts).

[0120] Suitable examples of fungi include laccases derived from strains of the genera *Aspergillus*, *Neurospora* (e.g., *Neurospora crassa*), *Streptococcus*, *Botrytis*, *Flammulina*, *Laminaria*, *Lentinula*, *Pleurotus*, *Coralus* (e.g., *Coralus longifolius* and *Trametes versicolor*), *Rhizoctonia* (e.g., *Rhizoctonia solani*), *Coprinus* (*Coprinus gracilistylus*, *Coprinus comatus*, *Coprinus friesii*, and *Coprinus plicatilis*), *Pterocarya* (e.g., *Pterocarya condelleana*), *Lycopus* (e.g., *Lycopus macrosporus*), *Symplocos* (e.g., *Symplocos ferruginosa*), *Schytalidium* (e.g., *S. thermophilum*), *Schytalidium* (e.g., *S. thermophilum*), *Polyporus* (e.g., *P. pinsitus*), *Neurospora* (e.g., *Symplocos ferruginosa*), or *C. irsutus* (e.g., *C. irsutus*).

[0121] Suitable examples of bacteria include laccases derived from strains of the genus Bacillus. Laccases derived from the genera *Coprinus* or *Desmodium* are preferred; particularly laccases derived from *Coprinus gracilistylus*; or laccases derived from *Desmodium thermophilum*.

[0122] Examples of other oxidases include, but are not limited to, amino acid oxidases, glucose oxidases, lactate oxidases, galactose oxidases, polyol oxidases, and aldose oxidases. Oxidases and their corresponding substrates can be used as enzyme systems for producing hydrogen peroxide, and therefore can be used as sources of hydrogen peroxide. Several enzymes (such as peroxidases, halogen peroxidases, and perhydrolases) require a source of hydrogen peroxide.

[0123] Enzymes can be in liquid form and can be dispersed in detergent compositions. Enzymes can also be added in solid form or as capsules. Solid forms will include particles, such as layered particles, that can be manufactured by fluidized bed coating. Preferably, the microcapsules and particles are coated with a polymer that provides triggered release via an ionic strength trigger, such that the particles and / or capsules are stable in the product but release their enzyme payload upon dilution in water. Examples of such polymer coatings include cellulose derivatives, such as hydroxypropyl methylcellulose derivatives, particularly hydroxypropyl methylcellulose phthalate and cellulose acetate phthalate. Another preferred polymer coating is polyvinyl alcohol. Further preferably, any capsules and / or particles are density-matched to the surrounding liquid matrix to promote stability and prevent the deposition of a visible phase. On the other hand, enzymes can be added as capsules and / or microcapsules derived from interfacial polymerization reactions of polyamines, preferably branched polyamines. The microcapsules can be manufactured by reacting polyamines, for example, those sold by BASF under the trade name Lupasol, with acyl chlorides.

[0124] For particles, the preferred particle size is from 50 to 1000 μm, more preferably from 50 to 500 μm, and most preferably from 100 to 250 μm. For capsules, the preferred particle size is from 1 to 1000 μm, more preferably from 5 to 200 μm, and most preferably from 10 to 100 μm.

[0125] Based on the total weight of the detergent composition, the enzyme may be present in an amount from 0.01 to 5 wt%, preferably 0.1 to 2 wt%, more preferably from 0.5 to 1.5 wt%.

[0126] Builders and co-builders

[0127] The detergent composition may further contain about 0% to 65% by weight, such as about 5% to about 50%, of detergent builders or co-builders, or mixtures thereof. In the detergent, the level of builders is typically 40% to 65%, particularly 50% to 65%. Builders and / or co-builders may be chelating agents, particularly, that form water-soluble complexes with Ca and Mg. Any builders and / or co-builders known in the art for use in laundry detergents may be used. Non-limiting examples of detergent builders include zeolites, diphosphates (pyrophosphates), triphosphates such as sodium triphosphate (STP or STPP), carbonates such as sodium carbonate, soluble silicates such as sodium metasilicate, layered silicates (e.g., SKS-6 from Hoechst), ethanolamines such as 2-aminoethanol (MEA), diethanolamine (DEA, also known as 2,2'-iminodiethanol), triethanolamine (TEA, also known as 2,2',2"-metaaminotriethanol), and (carboxymethyl)inulin (CMI), and combinations thereof.

[0128] The detergent composition may also contain 0% to 50% by weight, such as about 5% to about 30%, of a detergent co-agent. The detergent composition may contain a co-agent alone, or in combination with a builder such as a zeolite builder. Non-limiting examples of co-agents include homopolymers of polyacrylates or copolymers thereof, such as poly(acrylic acid) (PAA) or copolymers of (acrylic acid / maleic acid) (PAA PMA). Other non-limiting examples include citrates, chelating agents such as aminocarboxylates, aminopolycarboxylates, and phosphonates, as well as alkyl- or alkenyl succinic acids. Other specific examples include 2,2',2"-N-aminotriacetic acid (NTA), ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA), iminodisuccinic acid (IDS), ethylenediamine- / V, / V'-disuccinic acid (EDDS), methylglycine diacetic acid (MGDA), glutamic acid- / V, / V-diacetic acid (GLDA), 1-hydroxyethane-1,1-diphosphonic acid (HEDP), ethylenediaminetetra(methylenephosphonic acid) (EDTMPA), and diethylenetriaminepenta(methylenephosphonic acid) (DTMPA or DTPMP). A) N-(2-hydroxyethyl)iminodiacetic acid (EDG), aspartic acid- / V-monoacetic acid (ASMA), aspartic acid-Λ / , / V-diacetic acid (ASDA), aspartic acid- / V-monopropionic acid (ASMP), iminodisuccinic acid (IDA), / V-(2-sulfomethyl)-aspartic acid (SMAS), / V-(2-sulfoethyl)-aspartic acid (SEAS), / V-(2-sulfomethyl)-glutamic acid (SMGL), / V-(2-sulfoethyl)-glutamic acid (SEGL), / V-methyliminodiacetic acid (Ml) DA), α-alanine- / V, / V-diacetic acid (a-ALDA), serine- / V, / V-diacetic acid (SEDA), isoserine- / V, / V-diacetic acid (ISDA), phenylalanine- / V, / V-diacetic acid (PHDA), aminoanilic acid- / V, / V-diacetic acid (ANDA), sulfanilamide- / V, / V-diacetic acid (SLDA), taurine- / V, / V-diacetic acid (TUDA), and sulfonylmethyl- / V, / V-diacetic acid (SMDA), / V-(2-hydroxyethyl)ethylenediamine- / V, / V', / V"-triacetic acid (HEDTA), diethanolamine glycine (DEG), diethylenetriaminepenta (methylenephosphonic acid) (DTPMP), aminotris(methylenephosphonic acid) (ATMP), and combinations thereof and salts thereof. Other exemplary builders and / or co-builders are described, for example, in WO 09 / 102854 and US 5977053.

[0129] bleaching system

[0130] The detergent composition may contain 0%-30% by weight, such as about 1% to about 20%, of a bleaching system. Any bleaching system known in the art for use in laundry detergents may be used. Suitable bleaching system components include bleaching catalysts, photobleaching agents, bleaching activators, hydrogen peroxide sources (such as sodium percarbonate, sodium perborate, and hydrogen peroxide-urea (1:1)), pre-prepared peracids, and mixtures thereof. Suitable pre-prepared peracids include, but are not limited to, peroxycarboxylic acids and salts, disperoxydicarboxylic acids, perimino acids and salts, peroxymonosulfate and salts, for example... And mixtures thereof. Non-limiting examples of bleaching systems include peroxide-based bleaching systems, which may include, for example, inorganic salts combined with a bleaching activator that forms a peracid, including alkali metal salts such as perborates (typically monohydrates or tetrahydrates), percarbonates, persulfates, sodium salts of perphosphates, and persilicates. The term bleaching activator herein means a compound that reacts with hydrogen peroxide to form a peracid via perhydrolysis. The peracid thus formed constitutes the activated bleaching agent.

[0131] Preferably, in addition to the bleaching catalyst, particularly an organic bleaching catalyst, the bleaching component also includes a peracid source. The peracid source may be selected from (a) pre-prepared peracid; (b) percarbonate, perborate, or persulfate (hydrogen peroxide source), preferably in combination with a bleaching activator; and (c) perhydrolases and esters that form peracid in situ in the presence of water during textile or hard surface treatment steps.

[0132] polymer

[0133] The detergent composition may contain 0%-10% by weight, such as 0.5%-5%, 2%-5%, 0.5%-2%, or 0.2%-1% of a polymer. Any polymer known in the art for use in detergents may be used. The polymer may act as a co-adjuvant as mentioned above, or may provide anti-redeposition, fiber protection, stain removal, stain inhibition, grease removal, and / or defoaming properties. Some polymers may have more than one of the above-mentioned properties and / or more than one of the following characteristics. Exemplary polymers include (carboxymethyl) cellulose (CMC), polyvinyl alcohol (PVA), poly(vinylpyrrolidone) (PVP), poly(ethylene glycol) or poly(ethylene oxide) (PEG), ethoxylated poly(ethyleneimine), carboxymethyl inulin (CMI), and polycarboxylate esters (such as PAA, PAA PMA), polyaspartic acid, and lauryl methacrylate / acrylic acid copolymers, hydrophobically modified CMC (HM-CMC) and silicones, copolymers of terephthalic acid and oligomeric glycols, copolymers of poly(ethylene terephthalate) and poly(ethylene terephthalate) (PET-POET), PVP, poly(vinylimidazolium) (PVI), poly(vinylpyridine- / V-oxide) (PVPO or PVPNO), and polyvinylpyrrolidone-vinylimidazolium (PVPVI). Other exemplary polymers include sulfonated polycarboxylate salts, polyethylene oxide and polypropylene oxide (PEO-PPO), and ethoxylated sulfate bisquaternary ammonium salts. Other exemplary polymers are disclosed, for example, in WO 2006 / 130575. Salts of the above polymers are also considered.

[0134] Fabric colorant

[0135] The detergent compositions of the present invention may further comprise fabric colorants, such as dyes or pigments, which, when formulated in the detergent composition, can deposit onto the fabric when the fabric comes into contact with a washing liquid containing the detergent composition, thereby altering the hue of the fabric by absorbing / reflecting visible light. Fluorescent whitening agents emit at least some visible light. In contrast, fabric colorants alter the hue of surfaces because they absorb at least a portion of the visible spectrum. Suitable fabric colorants include dyes and dye-clay conjugates, and may also include pigments. Suitable dyes include small molecule dyes and polymer dyes. Suitable small molecule dyes include those selected from the group consisting of dyes falling into the color index (CI) classification of direct blue, direct red, direct violet, acid blue, acid red, acid violet, basic blue, basic violet and basic red, or mixtures thereof, such as those described in WO 2005 / 03274, WO 2005 / 03275, WO 2005 / 03276 and EP 1876226 (incorporated hereby by reference). The detergent composition preferably contains from about 0.00003 wt% to about 0.2 wt%, from about 0.00008 wt% to about 0.05 wt%, or even from about 0.0001 wt% to about 0.04 wt% of a fabric toner. The composition may contain from 0.0001 wt% to 0.2 wt% of a fabric toner, which may be particularly preferred when the composition is in the form of unit dose sachets. Suitable toners are also disclosed, for example, in WO2007 / 087257 and WO 2007 / 087243.

[0136] auxiliary materials

[0137] Any detergent component known in the art for use in laundry detergents may also be used. Other optional detergent components include, alone or in combination, corrosion inhibitors, shrinkage inhibitors, anti-fouling agents, anti-redeposition agents, wrinkle inhibitors, bactericides, adhesives, corrosion inhibitors, disintegrants / disintegrants, dyes, enzyme stabilizers (including boric acid, borates, CMC, and / or polyols such as propylene glycol), fabric conditioners (including clay), fillers / processing aids, optical brighteners / foam enhancers, foam promoters, foam (soap foam) regulators, fragrances, soil suspenders, fabric softeners, defoamers, dulling inhibitors, and wicking agents. Any ingredient known in the art for use in laundry detergents may be used. The selection of such ingredients is well within the skill of a person skilled in the art.

[0138] The detergent compositions of the present invention may also contain dispersants. In particular, powdered detergents may contain dispersants. Suitable water-soluble organic materials include homopolymer or copolymer acids or salts thereof, wherein the polycarboxylic acid comprises at least two carboxyl groups separated from each other by no more than two carbon atoms. Suitable dispersants are described, for example, in Powdered Detergents, Surfactant Science Series Volume 71, Marcel Dekker, Inc.

[0139] The detergent compositions of the present invention may further comprise one or more stain inhibitors. Suitable polymer stain inhibitors include, but are not limited to, polyvinylpyrrolidone polymers, polyamine / V-oxide polymers, copolymers of N-vinylpyrrolidone and / or V-vinylimidazole, polyvinyloxazolidinone and polyvinylimidazole, or mixtures thereof. When present in the subject composition, the stain inhibitor may be present at a level from about 0.0001% to about 10%, from about 0.01% to about 5%, or even from about 0.1% to about 3% by weight of the composition.

[0140] The detergent compositions of the present invention may preferably contain additional components that can color the articles to be cleaned, such as optical brighteners or fluorescent whitening agents. When present, the brightening agent is preferably at a level of about 0.01% to about 0.5%. Any optical brightener suitable for laundry detergent compositions may be used in the compositions of the present invention. The most commonly used optical brighteners are those belonging to the categories of diaminostilbene-sulfonic acid derivatives, diarylpyrazoline derivatives, and bisphenyl-stilbene derivatives.

[0141] The detergent compositions of the present invention may also contain one or more detergency polymers that facilitate the removal of dirt from fabrics such as cotton and polyester-based fabrics, particularly hydrophobic dirt from polyester-based fabrics. The detergency polymers may be, for example, polymers based on nonionic or anionic terephthalates, polyvinylcaprolactam and related copolymers, vinyl graft copolymers, polyester polyamides, see, for example, Chapter 7 of *Powdered Detergents*, *Surfactantscience series*, volume 71, Marcel Dekker, Inc. Another type of detergency polymer is an amphiphilic alkoxylated grease-cleaning polymer comprising a core structure and a plurality of alkoxylated groups attached to the core structure. As described in detail in WO 2009 / 087523, the core structure may comprise a polyalkylimide structure or a polyalkanolamine structure. Furthermore, random graft copolymers are suitable detergency polymers. Suitable graft copolymers are described in more detail in WO 2007 / 138054, WO 2006 / 108856 and WO 2006 / 113314.

[0142] The detergent compositions of the present invention may further comprise one or more anti-redeposition agents, such as carboxymethyl cellulose (CMC), polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), polyoxyethylene and / or polyethylene glycol (PEG), homopolymers of acrylic acid, copolymers of acrylic acid and maleic acid, and ethoxylated polyethyleneimine. Cellulose-based polymers described below under the detergency polymers can also be used as anti-redeposition agents.

[0143] The detergent compositions of the present invention may further comprise one or more rheology modifiers, structural agents, or thickeners, different from viscosity reducers. Rheology modifiers are selected from the group consisting of: non-polymer crystalline hydroxyl-functionalized materials, and polymeric rheology modifiers that impart shear-thinning characteristics to the aqueous liquid matrix of the liquid detergent composition. The rheology and viscosity of the detergent can be modified and adjusted by methods known in the art, for example as shown in EP 2169040.

[0144] Other suitable auxiliary materials include, but are not limited to, anti-shrinkage agents, anti-wrinkle agents, bactericides, adhesives, carriers (such as oily materials and water), dyes, enzyme stabilizers, fabric softeners, fillers, foam regulators, water-soluble solvents, fragrances, pigments, defoamers, solvents, and structural agents and / or structural elastic agents from liquid detergents.

[0145] application

[0146] The detergent compositions of the present invention can be in any convenient form, such as strips, uniform tablets, tablets having two or more layers, pouches having one or more compartments, regular or dense powders, granules, pastes, gels, or regular, dense or concentrated liquids. Preferably, the detergent composition is in liquid form, such as a gel, a regular, dense or concentrated liquid.

[0147] The pouch can be configured as a single-compartment or multi-compartment pouch. It can have any form, shape, and material suitable for retaining the composition, for example, preventing release of the composition from the pouch before contact with water. The pouch is made of a water-soluble membrane that surrounds an internal volume. This internal volume can be divided into compartments within the pouch. Preferred membranes are polymeric materials, preferably polymers forming membranes or sheets. Preferred polymers, copolymers, or derivatives thereof are selected from polyacrylates, as well as water-soluble acrylate copolymers, methylcellulose, carboxymethylcellulose, sodium dextrin, ethylcellulose, hydroxyethylcellulose, hydroxypropyl methylcellulose, maltodextrin, polymethyl acrylate, most preferably polyvinyl alcohol copolymers, and hydroxypropyl methylcellulose (HPMC). Preferably, the level of a polymer, such as PVA, in the membrane is at least about 60%. The preferred average molecular weight will typically be from about 20,000 to about 150,000. The membrane may also have blend compositions comprising hydrolyzable and water-soluble polymer blends, such as polylactide and polyvinyl alcohol (as known under trade reference M8630, sold by MonoSol LLC, Indiana, USA), plus plasticizers, such as glycerin, ethylene glycerin, propylene glycol, sorbitol, and mixtures thereof. The pouch may contain a solid laundry detergent composition or portions thereof separated by a water-soluble membrane and / or a liquid detergent composition or portions thereof. The composition of the liquid component compartment may differ from that of the solid-containing compartment: US 2009 / 0011970 A1.

[0148] Detergent components can be physically separated from each other by compartments in different layers of water-soluble sachets or tablets. This avoids negative storage interactions between components. The different solubility profiles of each compartment may also result in delayed dissolution of the selected components in the washing solution.

[0149] When in liquid form, the detergent composition may be aqueous, typically containing at least 20% and up to 95% water by weight, such as up to about 70%, up to about 65%, up to about 55%, up to about 45%, or up to about 35%. Other types of liquid carriers may be included in the liquid detergent composition, including but not limited to alkanols, amines, glycols, ethers, and polyols. The liquid detergent composition may contain from 0% to 30% organic solvents.

[0150] Liquid detergent compositions can also be non-aqueous.

[0151] The detergent composition may be a laundry soap bar. The enzyme preparations of the present invention may be added to the laundry soap bar and used for hand washing clothes, fabrics, and / or textiles. The term laundry soap bar includes laundry bars, soap bars, combination bars, synthetic detergent bars, and detergent bars. The types of bars generally differ in the types of surfactants they contain; the term laundry soap bar includes those containing soaps derived from fatty acids and / or synthetic soaps. Laundry soap bars have a physical form that is solid at room temperature rather than liquid, gel, or powder. The term solid is defined as a physical form that does not change significantly over time; that is, if a solid object (e.g., a laundry soap bar) is placed inside a container, the solid object does not change to fill the container in which it is placed. A bar is generally a solid in bar form, but may be in other solid shapes, such as round or oval.

[0152] Laundry soap bars may contain one or more additional enzymes, protease inhibitors such as peptide aldehydes (or bisulfite adducts or hemiacetal adducts), boric acid, borates, borax and / or phenylboronic acid derivatives such as 4-formylphenylboronic acid, one or more soaps or synthetic surfactants, polyols (such as glycerol), pH-controlling compounds (such as fatty acids, citric acid, acetic acid and / or formic acid), and / or salts of monovalent cations and organic anions, wherein the monovalent cation may be, for example, Na+. + K + or NH4 + Furthermore, the organic anion can be, for example, formate, acetate, citrate, or lactate, such that the salt of the monovalent cation and the organic anion can be, for example, sodium formate.

[0153] Laundry soap bars may also contain coordinating agents (like EDTA and HEDP), fragrances and / or different types of fillers, surfactants (e.g., anionic synthetic surfactants), builders, polymer detergents, detergent chelators, stabilizers, fillers, dyes, colorants, dyeing inhibitors, alkoxylated polycarbonates, defoamers, structural agents, binders, solvents, bleaching activators, clay detergents, anti-redeposition agents, polymer dispersants, brighteners, fabric softeners, fragrances and / or other compounds known in the art.

[0154] Laundry soap bars can be processed in conventional laundry soap bar manufacturing equipment, such as, but not limited to, mixers, pressing machines (e.g., two-stage vacuum pressing machines), extruders, cutters, logo molds, cooling channels, and packaging devices. The invention is not limited to preparing laundry soap bars by any single method. The premix of the invention can be added to the soap at different stages of the method. For example, a premix containing soap, an enzyme preparation, optionally one or more additional enzymes, a protease inhibitor, and salts of monovalent cations and organic anions can be prepared, and the mixture is then pressed into bars. The enzyme preparation and optionally additional enzymes can be added simultaneously with the protease inhibitor, for example, in liquid form. In addition to the mixing and pressing steps, the method may further include milling, extrusion, cutting, molding, cooling, and / or packaging steps.

[0155] The detergent compositions of the present invention can be used in cosmetic formulations, which can be in the form of mousse, gel, spray or varnish, and can be used in rinse-off or leave-on applications.

[0156] Detergent compositions can be used as hair products, especially rinse-out or leave-on products, and are particularly used for washing, conditioning and / or conditioning hair, maintaining hairstyles, and shaping, coloring, bleaching, permanently reshaping or loosening hair.

[0157] The detergent compositions of the present invention can also be used as care or hygiene products, such as protective, therapeutic or care creams for the face, hands or body, protective or care body lotions, gels or mousses for caring for or cleansing the skin, or alternatively as products for makeup or removing makeup from the skin, lips, nails and eyelashes.

[0158] Experimental Section

[0159] This disclosure will now be illustrated with working examples, which are intended to illustrate the work of this disclosure and are not intended to restrictively imply any limitation on the scope of this disclosure. Other examples are also possible within the scope of this disclosure.

[0160] Material:

[0161] -Standard liquid laundry detergent base (prepared in a laboratory)

[0162] -Different types of guar gum

[0163] -250ppm hard water

[0164] -Savinase Ultra 16L (Protein)

[0165] - Cut the standard stain from the supplier into small 5cm x 5cm fabric samples.

[0166] Experimental procedure:

[0167] Step 1. Preparation of standard liquid laundry detergent base and guar gum solution

[0168] Pre-prepared standard liquid laundry detergent base using the following formulation:

[0169]

[0170]

[0171] The hydrated guar gum solution is prepared as follows: First, disperse the guar gum in water by adding guar gum powder to distilled water while continuously stirring at 25°C. Then, adjust the pH to 4-5 using HCl. Continue stirring for another 10 minutes. Add the calculated amounts of detergent, enzyme, and guar gum solution to a basin for washing.

[0172] Step 2. Measure reflectance (before washing)

[0173] After calibration, the reflectance of the fabric was measured using a CIELAB (L*a*b*) spectrophotometer. For each fabric, five measurement points were taken at different spots.

[0174] Step 3. Wash the fabric

[0175] instrument Water wash resistance tester (SDL Atlas Rotawash M228) temperature 30℃ Washing time 60min Dosage per basin 500g Detergent Standard liquid detergent base Detergent dosage 1.5g / L stain Egg yolk, chocolate soy milk, coffee with milk

[0176] Wash the following fabrics:

[0177] 1. Based on these parameters, add the calculated amounts of standard liquid laundry detergent base, enzymes, and guar gum solution to the basin.

[0178] 2. Adjust the final pH of all washing solutions to 8-9 to optimize enzyme efficiency.

[0179] 3. After washing, squeeze the fabric.

[0180] 4. To rinse, place the fabric in a clean beaker containing approximately 500 mL of tap water and stir by hand for 10 seconds. Repeat twice.

[0181] 5. After rinsing, squeeze the fabric.

[0182] 6. Dry on aluminum foil overnight at room temperature.

[0183] Step 4. Measure reflectance (after drying)

[0184] As in step 2, a CIELAB (L*a*b*) spectrophotometer has been used.

[0185] Step 5. Calculate color difference / stain removal percentage / whiteness index

[0186] The average L*, a*, and b* values ​​for each textile sample before and after washing have been calculated. Color difference (ΔE), stain removal percentage (SRP), and whiteness index (SRI) have been calculated using the average L*, a*, and b values ​​in the following equations:

[0187]

[0188]

[0189]

[0190] result

[0191] The results are shown in the table below:

[0192] Table 1

[0193]

[0194] Amphoteric PS (polysaccharide) 1 is carboxymethyl hydroxypropyl trimethylammonium chloride guar gum with an average molecular weight of about 2,000,000 Daltons and a cationic degree of substitution of 0.09 and an anionic degree of substitution of 0.17, and is available from Solvay.

[0195] Amphoteric PS2 is carboxymethyl hydroxypropyl trimethylammonium chloride guar gum with an average molecular weight of about 2,000,000 Daltons and a cationic degree of substitution of 0.045 and an anionic degree of substitution of 0.17, and is available from Solvay.

[0196] The cationic PS is guar hydroxypropyltrimethylammonium chloride, which has an average molecular weight of about 500,000 Daltons and a cationic substitution degree of about 0.13, and is available from Solvay.

[0197] Anionic PS is carboxymethyl hydroxypropyl guar gum with an average molecular weight of about 2,000,000 Daltons and an anionic substitution degree of about 0.17, and is available from Solvay.

[0198] The results showed that, compared with a baseline (without any guar gum) or a comparative composition containing cationic or anionic guar gum, the amphoteric guar gum according to the invention resulted in a more significant ΔE. This demonstrates that amphoteric guar gum can enhance the detergent properties of enzymes used on fabrics, which in turn leads to enhanced cleaning performance of enzyme-containing detergent compositions.

Claims

1. Use of an amphoteric polysaccharide for enhancing the detergent properties of an enzyme of an enzyme-containing detergent composition, wherein the detergent properties of the enzyme refer to the stain removal performance of the enzyme to hydrolyze or remove a stain, and wherein, said enzyme is selected from proteases, and the amphoteric polysaccharide is an amphoteric galactomannan having an average molecular weight between 1,000,000 and 2,500,000 Dalton, a DS value greater than or equal to its DS 阳离子 value 阴离子 value and a DS 阳离子 value from 0.001 to 0.

1.

2. Use according to claim 1, wherein, The amphoteric polysaccharide is amphoteric guar.

3. Use according to any one of claims 1 to 2, wherein, The amphoteric polysaccharide is present in an amount from 0.01 to 5 wt% based on the total weight of the detergent composition.

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